Guide to the Human Genome
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Search of human proteins with 4505343

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505343 nuclear cap binding protein subunit 1, 80kDa [Homo
sapiens]
         (790 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505343 nuclear cap binding protein subunit 1, 80kDa [Homo sa...  1615   0.0  
gi|31377634 guanylate binding protein 4 [Homo sapiens]                 43   0.001
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap...    37   0.093
gi|34878777 ring finger protein 20 [Homo sapiens]                      36   0.12 
gi|24308229 protein kinase C and casein kinase substrate in neur...    36   0.12 
gi|239753269 PREDICTED: upstream binding transcription factor, R...    36   0.16 
gi|239747816 PREDICTED: upstream binding transcription factor, R...    36   0.16 
gi|239741686 PREDICTED: upstream binding transcription factor, R...    36   0.16 
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     36   0.16 
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]          36   0.16 
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]              35   0.27 
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]              35   0.27 
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     35   0.27 
gi|46249349 homer 2 isoform 1 [Homo sapiens]                           35   0.27 
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    35   0.27 
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    35   0.27 
gi|239047795 pleckstrin homology domain containing, family A mem...    35   0.35 
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    35   0.35 
gi|10880975 hypothetical protein LOC57821 [Homo sapiens]               35   0.35 
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ...    34   0.46 
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]            34   0.46 
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]            34   0.46 
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]            34   0.46 
gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho...    34   0.46 
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            34   0.60 
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    34   0.60 
gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-l...    34   0.60 
gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-l...    34   0.60 
gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-l...    34   0.60 
gi|169208016 PREDICTED: similar to golgi autoantigen, golgin sub...    34   0.60 

>gi|4505343 nuclear cap binding protein subunit 1, 80kDa [Homo
           sapiens]
          Length = 790

 Score = 1615 bits (4181), Expect = 0.0
 Identities = 790/790 (100%), Positives = 790/790 (100%)

Query: 1   MSRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGEKSACSLESNLEGLAGVLEAD 60
           MSRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGEKSACSLESNLEGLAGVLEAD
Sbjct: 1   MSRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGEKSACSLESNLEGLAGVLEAD 60

Query: 61  LPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN 120
           LPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN
Sbjct: 61  LPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN 120

Query: 121 YNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWV 180
           YNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWV
Sbjct: 121 YNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWV 180

Query: 181 GKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLK 240
           GKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLK
Sbjct: 181 GKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLK 240

Query: 241 KDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEG 300
           KDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEG
Sbjct: 241 KDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEG 300

Query: 301 PVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELF 360
           PVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELF
Sbjct: 301 PVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELF 360

Query: 361 QLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHH 420
           QLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHH
Sbjct: 361 QLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHH 420

Query: 421 LSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPAN 480
           LSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPAN
Sbjct: 421 LSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPAN 480

Query: 481 PTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNPNQDDDDDEGFSFN 540
           PTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNPNQDDDDDEGFSFN
Sbjct: 481 PTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNPNQDDDDDEGFSFN 540

Query: 541 PLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQM 600
           PLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQM
Sbjct: 541 PLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQM 600

Query: 601 IAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELE 660
           IAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELE
Sbjct: 601 IAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELE 660

Query: 661 EAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMI 720
           EAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMI
Sbjct: 661 EAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMI 720

Query: 721 LTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILA 780
           LTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILA
Sbjct: 721 LTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILA 780

Query: 781 VFQQFCALQA 790
           VFQQFCALQA
Sbjct: 781 VFQQFCALQA 790


>gi|31377634 guanylate binding protein 4 [Homo sapiens]
          Length = 640

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 25/93 (26%), Positives = 52/93 (55%), Gaps = 9/93 (9%)

Query: 639 EILHSTIRKMNKHVLKIQKELEEAKEKLARQHKR--------RSDDDDRSSDRKDGVLEE 690
           +++ +  R   +++ +++K+LEE +E L R+H+R        + +       +K   L +
Sbjct: 529 QMMEAQERSFQEYMAQMEKKLEEERENLLREHERLLKHKLKVQEEMLKEEFQKKSEQLNK 588

Query: 691 QIERLQEKVESAQSEQKNLFLVI-FQRFIMILT 722
           +I +L+EK+ES ++EQ  L  ++     IMI+T
Sbjct: 589 EINQLKEKIESTKNEQLRLLKILDMASNIMIVT 621


>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
           sapiens]
          Length = 955

 Score = 36.6 bits (83), Expect = 0.093
 Identities = 32/160 (20%), Positives = 71/160 (44%), Gaps = 17/160 (10%)

Query: 549 QTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKM 608
           Q  +H   ++       L +  EV +  A+  +  L   +   E+  N  ++ A + ++M
Sbjct: 568 QKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVEL--NSEKVYAEMKEQM 625

Query: 609 IRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLAR 668
            + +       A+   S  L    ++ F+W+ L    ++  + +++++ E E+ K  L +
Sbjct: 626 EKVE-------ADLTRSKSLREKQSKEFLWQ-LEDIRQRYEQQIVELKLEHEQEKTHLLQ 677

Query: 669 QHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKN 708
           QH    D   R  +R       +IE L++++ +A  E +N
Sbjct: 678 QHNAEKDSLVRDHER-------EIENLEKQLRAANMEHEN 710


>gi|34878777 ring finger protein 20 [Homo sapiens]
          Length = 975

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 19/64 (29%), Positives = 41/64 (64%), Gaps = 3/64 (4%)

Query: 646 RKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSE 705
           +K    +  +++ L++ ++K  +++K+ +D+D   + RK   +EEQIE LQ+K+  A+ E
Sbjct: 668 KKSKAELEDLRQRLKDLEDKEKKENKKMADED---ALRKIRAVEEQIEYLQKKLAMAKQE 724

Query: 706 QKNL 709
           ++ L
Sbjct: 725 EEAL 728



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 3/61 (4%)

Query: 656 QKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQ---IERLQEKVESAQSEQKNLFLV 712
           +KE E  K+KL    K R    D+   + D   +++   I++L+ +++ AQ  QK + L+
Sbjct: 587 EKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLL 646

Query: 713 I 713
           +
Sbjct: 647 L 647


>gi|24308229 protein kinase C and casein kinase substrate in neurons
           1 [Homo sapiens]
          Length = 444

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 18/126 (14%)

Query: 646 RKMNKHVLKIQKELEEAKEK--LARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQ 703
           RK  K   K  KELE AK+   LA + ++ +   + +S  +  V  EQ ++LQ+KV+  +
Sbjct: 140 RKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTEQSVTPEQQKKLQDKVDKCK 199

Query: 704 SEQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMV 763
            + +              T+       +     TP Y   +E ++Q+F Q  Q  ++ +V
Sbjct: 200 QDVQK-------------TQEKYEKVLEDVGKTTPQY---MENMEQVFEQCQQFEEKRLV 243

Query: 764 TLENLL 769
            L+ +L
Sbjct: 244 FLKEVL 249


>gi|239753269 PREDICTED: upstream binding transcription factor, RNA
           polymerase I-like 6 [Homo sapiens]
          Length = 400

 Score = 35.8 bits (81), Expect = 0.16
 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 13/120 (10%)

Query: 595 RNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKM-----N 649
           RNHP     L+   IR          NW   S++        V +IL    +++      
Sbjct: 101 RNHPDFPKRLLTAYIRF------FKENWPQYSQMYPGMRSQEVTKILSKKYKELPEQMKQ 154

Query: 650 KHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNL 709
           KH+   +KE +E +EKLAR  +   D D +   +K  + +    ++Q+KV+    E ++L
Sbjct: 155 KHIQDFRKEKQEFEEKLARFREEHPDLDQKG--KKSDICKRVQTKVQKKVQKNIEEVRSL 212


>gi|239747816 PREDICTED: upstream binding transcription factor, RNA
           polymerase I-like 6 [Homo sapiens]
          Length = 400

 Score = 35.8 bits (81), Expect = 0.16
 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 13/120 (10%)

Query: 595 RNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKM-----N 649
           RNHP     L+   IR          NW   S++        V +IL    +++      
Sbjct: 101 RNHPDFPKRLLTAYIRF------FKENWPQYSQMYPGMRSQEVTKILSKKYKELPEQMKQ 154

Query: 650 KHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNL 709
           KH+   +KE +E +EKLAR  +   D D +   +K  + +    ++Q+KV+    E ++L
Sbjct: 155 KHIQDFRKEKQEFEEKLARFREEHPDLDQKG--KKSDICKRVQTKVQKKVQKNIEEVRSL 212


>gi|239741686 PREDICTED: upstream binding transcription factor, RNA
           polymerase I-like 6 [Homo sapiens]
          Length = 400

 Score = 35.8 bits (81), Expect = 0.16
 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 13/120 (10%)

Query: 595 RNHPQMIAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKM-----N 649
           RNHP     L+   IR          NW   S++        V +IL    +++      
Sbjct: 101 RNHPDFPKRLLTAYIRF------FKENWPQYSQMYPGMRSQEVTKILSKKYKELPEQMKQ 154

Query: 650 KHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNL 709
           KH+   +KE +E +EKLAR  +   D D +   +K  + +    ++Q+KV+    E ++L
Sbjct: 155 KHIQDFRKEKQEFEEKLARFREEHPDLDQKG--KKSDICKRVQTKVQKKVQKNIEEVRSL 212


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 35.8 bits (81), Expect = 0.16
 Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 2/115 (1%)

Query: 646  RKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSE 705
            RK  + +  I+K+L    E+   Q+K+ ++      + K    E ++  L+EK++S +S 
Sbjct: 1642 RKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESS 1701

Query: 706  QKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQ 760
            Q    +V   R    +  +  + E D    +   Y+  I  LQ+   +  +++Q+
Sbjct: 1702 QSETLIV--PRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQR 1754


>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
          Length = 1711

 Score = 35.8 bits (81), Expect = 0.16
 Identities = 18/83 (21%), Positives = 41/83 (49%)

Query: 627 ELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDG 686
           ++ RD       E     IR++ +  L++ ++L+E+ + +   H       + + D++  
Sbjct: 429 DVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKEIK 488

Query: 687 VLEEQIERLQEKVESAQSEQKNL 709
            L E+IERL+ K+  +   ++ L
Sbjct: 489 KLNEEIERLKNKIADSNRLERQL 511


>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
          Length = 284

 Score = 35.0 bits (79), Expect = 0.27
 Identities = 19/66 (28%), Positives = 39/66 (59%), Gaps = 2/66 (3%)

Query: 639 EILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDD--DDRSSDRKDGVLEEQIERLQ 696
           + L   ++     V K  + ++EA+EKL +  K+ +D   D  S +R+  ++EE+++R Q
Sbjct: 44  QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103

Query: 697 EKVESA 702
           E++ +A
Sbjct: 104 ERLATA 109



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 18/56 (32%), Positives = 32/56 (57%), Gaps = 3/56 (5%)

Query: 657 KELEEAKEKLARQHKRRSDDDDRSSD---RKDGVLEEQIERLQEKVESAQSEQKNL 709
           +E  E +E   ++ K  ++D DR  +   RK  +LE ++ER +E+ E A+S  + L
Sbjct: 138 EEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQL 193



 Score = 30.0 bits (66), Expect = 8.7
 Identities = 14/65 (21%), Positives = 38/65 (58%), Gaps = 2/65 (3%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDG--VLEEQIERLQEKVESA 702
           +  +N+ +  +++EL+ A+E+LA   ++  + +  + + + G  V+E +  + +EK+E  
Sbjct: 85  VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQ 144

Query: 703 QSEQK 707
           + + K
Sbjct: 145 EMQLK 149


>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
          Length = 284

 Score = 35.0 bits (79), Expect = 0.27
 Identities = 19/66 (28%), Positives = 39/66 (59%), Gaps = 2/66 (3%)

Query: 639 EILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDD--DDRSSDRKDGVLEEQIERLQ 696
           + L   ++     V K  + ++EA+EKL +  K+ +D   D  S +R+  ++EE+++R Q
Sbjct: 44  QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103

Query: 697 EKVESA 702
           E++ +A
Sbjct: 104 ERLATA 109



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 10/98 (10%)

Query: 657 KELEEAKEKLARQHKRRSDDDDRSSD---RKDGVLEEQIERLQEKVESAQSEQKNLFLVI 713
           +E  E +E   ++ K  ++D DR  +   RK  +LE ++ER +E+ E A+S+  +L    
Sbjct: 138 EEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDL---- 193

Query: 714 FQRFIMILTEHL--VRCETDGTSVLTPWYKNCIERLQQ 749
            +  + I+T +L  +  + D  S     Y+  I+ L++
Sbjct: 194 -EEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEE 230



 Score = 30.0 bits (66), Expect = 8.7
 Identities = 14/65 (21%), Positives = 38/65 (58%), Gaps = 2/65 (3%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDG--VLEEQIERLQEKVESA 702
           +  +N+ +  +++EL+ A+E+LA   ++  + +  + + + G  V+E +  + +EK+E  
Sbjct: 85  VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQ 144

Query: 703 QSEQK 707
           + + K
Sbjct: 145 EMQLK 149


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 35.0 bits (79), Expect = 0.27
 Identities = 28/122 (22%), Positives = 58/122 (47%), Gaps = 4/122 (3%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQS 704
           I K+ +   K+Q+EL++  + L +    R   +++  DR  G ++E+   LQE++E  + 
Sbjct: 817 IEKLKERSSKLQEELDKYSQALRKNEILRQTIEEK--DRSLGSMKEENNHLQEELERLRE 874

Query: 705 EQKNLFLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVT 764
           EQ     V   + +  +TE  +  E    + +    +  I+  Q+I    +Q   Q + +
Sbjct: 875 EQSRTAPVADPKTLDSVTE--LASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQS 932

Query: 765 LE 766
           L+
Sbjct: 933 LQ 934


>gi|46249349 homer 2 isoform 1 [Homo sapiens]
          Length = 343

 Score = 35.0 bits (79), Expect = 0.27
 Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 10/149 (6%)

Query: 566 LAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQMIAVLVDKMIRTQIVDCAAVANWIFS 625
           L KF E F+ + E+ +      +   E   NH Q  +V        +    A  AN    
Sbjct: 96  LTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQASSV---NGTDDEKASHAGPANTHLK 152

Query: 626 SE-------LSRDFTRLFVWEILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDD 678
           SE       L++    +  WEI   T+R+ N  +    +E   + E+  RQ     D++D
Sbjct: 153 SENDKLKIALTQSAANVKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDEND 212

Query: 679 RSSDRKDGVLEEQIERLQEKVESAQSEQK 707
           R  ++ D + E+  E  +EK ++ Q +++
Sbjct: 213 RLRNKIDELEEQCSEINREKEKNTQLKRR 241


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
           b [Homo sapiens]
          Length = 1524

 Score = 35.0 bits (79), Expect = 0.27
 Identities = 15/54 (27%), Positives = 32/54 (59%)

Query: 656 QKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNL 709
           +++L+E ++K+  + ++  +D+ R+S     + EE+ E     +ES  +EQK L
Sbjct: 640 EEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKEL 693



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 641 LHSTIRKMNKHVLKIQKELEEAKEKLARQH-KRRSDDDDRSSDRKDGVLEEQIERLQEKV 699
           L ST   +  +V  +++  +E +E  A QH K R +   R   RK+  L+EQ ++++EK 
Sbjct: 595 LVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQ 654

Query: 700 ES-AQSEQKN 708
           E   + EQ+N
Sbjct: 655 EKLKEDEQRN 664


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
           a [Homo sapiens]
          Length = 1556

 Score = 35.0 bits (79), Expect = 0.27
 Identities = 15/54 (27%), Positives = 32/54 (59%)

Query: 656 QKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNL 709
           +++L+E ++K+  + ++  +D+ R+S     + EE+ E     +ES  +EQK L
Sbjct: 672 EEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKEL 725



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 641 LHSTIRKMNKHVLKIQKELEEAKEKLARQH-KRRSDDDDRSSDRKDGVLEEQIERLQEKV 699
           L ST   +  +V  +++  +E +E  A QH K R +   R   RK+  L+EQ ++++EK 
Sbjct: 627 LVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQ 686

Query: 700 ES-AQSEQKN 708
           E   + EQ+N
Sbjct: 687 EKLKEDEQRN 696


>gi|239047795 pleckstrin homology domain containing, family A member
           7 [Homo sapiens]
          Length = 1121

 Score = 34.7 bits (78), Expect = 0.35
 Identities = 44/231 (19%), Positives = 88/231 (38%), Gaps = 31/231 (13%)

Query: 489 DESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNPNQDDDDDEGFSFNPLKIEVFV 548
           D  S    G+      A +   K+ +D    + KD+   +      +      LK     
Sbjct: 628 DRRSMPSMGYMTHTVSAPSLHGKSADDTYLQLKKDLEYLDLKMTGRDLLKDRSLKPVKIA 687

Query: 549 QTLLHLAAKSFSHSFSALAKFHEVFKTLAESD---EGKLHVLRVMFEVWRNHPQMIAVLV 605
           ++   +    F      L    +  + L E+    E  L VL    E +R+ PQ +  + 
Sbjct: 688 ESDTDVKLSIFCEQDRVLQDLEDKIRALKENKDQLESVLEVLHRQMEQYRDQPQHLEKIA 747

Query: 606 --DKMIRTQIVDCAAVANWIFSSELSRDFTRLF-VWEILHSTIRKMNKHVLKIQKELEEA 662
              K+++  +V   A        ELSR+ T +   W              LK++ ++E+ 
Sbjct: 748 YQQKLLQEDLVHIRA--------ELSRESTEMENAWN-----------EYLKLENDVEQL 788

Query: 663 KEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNLFLVI 713
           K+ L  QH+R     ++S  +KD      + R+++      + ++N  +++
Sbjct: 789 KQTLQEQHRRAFFFQEKSQIQKD------LWRIEDVTAGLSANKENFRILV 833


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 34.7 bits (78), Expect = 0.35
 Identities = 16/57 (28%), Positives = 37/57 (64%)

Query: 653  LKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNL 709
            LK++KEL+  KE +  Q K++ +D +R  ++ +    ++ + +QEK+++ + E+ +L
Sbjct: 2099 LKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHL 2155


>gi|10880975 hypothetical protein LOC57821 [Homo sapiens]
          Length = 508

 Score = 34.7 bits (78), Expect = 0.35
 Identities = 16/47 (34%), Positives = 33/47 (70%), Gaps = 1/47 (2%)

Query: 654 KIQKELEEAKEKLARQHKRRSDDDDRSSDRK-DGVLEEQIERLQEKV 699
           ++QK+LEE +EKL R+ +RR  ++++   R+ D V +  +++ +E+V
Sbjct: 341 ELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQV 387


>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
           sapiens]
          Length = 1150

 Score = 34.3 bits (77), Expect = 0.46
 Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 4/55 (7%)

Query: 653 LKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQK 707
           LK++++ EE KE    + +   DDD +S D K    EE+  + QE++E  + E++
Sbjct: 670 LKVEEQKEEQKELEKSEKEEDEDDDRKSEDDK----EEEERKRQEEIERQRRERR 720


>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 34.3 bits (77), Expect = 0.46
 Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)

Query: 641 LHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVE 700
           LH +IR   + V +++K+L   + KL      +   DD S+D K+  L  +I++L E + 
Sbjct: 293 LHESIRYWEQEVSELKKDLAILEAKLCFFTDNKEKLDDISNDEKNEFL-NKIKQLVETLH 351

Query: 701 SAQSEQKNL 709
           +A+ E K+L
Sbjct: 352 AARMEYKDL 360


>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 34.3 bits (77), Expect = 0.46
 Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)

Query: 641 LHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVE 700
           LH +IR   + V +++K+L   + KL      +   DD S+D K+  L  +I++L E + 
Sbjct: 293 LHESIRYWEQEVSELKKDLAILEAKLCFFTDNKEKLDDISNDEKNEFL-NKIKQLVETLH 351

Query: 701 SAQSEQKNL 709
           +A+ E K+L
Sbjct: 352 AARMEYKDL 360


>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 34.3 bits (77), Expect = 0.46
 Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)

Query: 641 LHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVE 700
           LH +IR   + V +++K+L   + KL      +   DD S+D K+  L  +I++L E + 
Sbjct: 293 LHESIRYWEQEVSELKKDLAILEAKLCFFTDNKEKLDDISNDEKNEFL-NKIKQLVETLH 351

Query: 701 SAQSEQKNL 709
           +A+ E K+L
Sbjct: 352 AARMEYKDL 360


>gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo
           sapiens]
          Length = 864

 Score = 34.3 bits (77), Expect = 0.46
 Identities = 27/133 (20%), Positives = 58/133 (43%), Gaps = 15/133 (11%)

Query: 639 EILHSTIRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEK 698
           ++L    R   K  L+ +++  E + +   Q K+R ++++ +S  K+ ++ E++ER++  
Sbjct: 594 KMLSKQRRAQKKAKLEEERKHAERERQQKNQKKKRDEEEEEASGLKEELIPEKLERVENP 653

Query: 699 VESAQS---EQKNL-----------FLVIFQRFIMILTEHLVRCETDGTSVLTPWYKNCI 744
           +E A       KNL           F + F++   +L    V+      +   PW   C+
Sbjct: 654 LEEAVKFLIPLKNLVADNIDTHLLAFEIYFRKGKFLLMLQSVK-RAFAINSNNPWLHECL 712

Query: 745 ERLQQIFLQHHQI 757
            R  +    H  +
Sbjct: 713 IRFSKSVSNHSNL 725


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 33.9 bits (76), Expect = 0.60
 Identities = 17/65 (26%), Positives = 39/65 (60%), Gaps = 1/65 (1%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQS 704
           +R+  + + + ++ L E +E+L  Q +R  + ++R  ++++  L EQ ERL E+ E  + 
Sbjct: 236 LREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEER-LHEQEERLCEQEERLRE 294

Query: 705 EQKNL 709
           +++ L
Sbjct: 295 QEERL 299



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 17/71 (23%), Positives = 39/71 (54%), Gaps = 6/71 (8%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLE------EQIERLQEK 698
           +R+  + + + ++ L E +E+L  Q +R  + ++R  + ++ + E      EQ ERL+E+
Sbjct: 215 LREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQ 274

Query: 699 VESAQSEQKNL 709
            E    +++ L
Sbjct: 275 EERLHEQEERL 285



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 17/64 (26%), Positives = 37/64 (57%), Gaps = 1/64 (1%)

Query: 646 RKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSE 705
           R+  + + + ++ L E +E+L  Q +R  + ++R  ++++  L EQ ERL E+ E  +  
Sbjct: 195 RRQEERLREQEERLREQEERLREQEERLCEQEERLREQEER-LREQEERLCEQEERLREH 253

Query: 706 QKNL 709
           ++ L
Sbjct: 254 EERL 257



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 15/65 (23%), Positives = 39/65 (60%), Gaps = 1/65 (1%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQS 704
           +R+  + + + ++ L E +E+L  Q +R  + ++R  ++++ + E++ ERL+E  E    
Sbjct: 201 LREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQE-ERLREHEERLCE 259

Query: 705 EQKNL 709
           +++ L
Sbjct: 260 QEERL 264



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 17/65 (26%), Positives = 39/65 (60%), Gaps = 1/65 (1%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQS 704
           +R+  + + + ++ L E +E+L  Q +R  + ++R  ++++  L EQ ERL E+ E  + 
Sbjct: 250 LREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEER-LREQEERLCEQEERLRE 308

Query: 705 EQKNL 709
           +++ L
Sbjct: 309 QEERL 313



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 16/54 (29%), Positives = 33/54 (61%), Gaps = 1/54 (1%)

Query: 656 QKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNL 709
           ++ L E +E+L  Q +R  + ++R  ++++  L EQ ERL E+ E  + +++ L
Sbjct: 275 EERLHEQEERLCEQEERLREQEERLCEQEER-LREQEERLCEQEERLREQEERL 327



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 15/63 (23%), Positives = 39/63 (61%), Gaps = 1/63 (1%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQS 704
           +R+  + + + ++ L E +E+L  Q +R  + ++R  ++++ + E++ ERL+E+ E    
Sbjct: 271 LREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQE-ERLREQEERLCE 329

Query: 705 EQK 707
           ++K
Sbjct: 330 QEK 332



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 18/69 (26%), Positives = 39/69 (56%), Gaps = 5/69 (7%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRK----DGVLEEQIERLQEKVE 700
           +R+  + + + ++ L E +E+L  Q +R  + ++R  +++       L E++E+L E+ E
Sbjct: 292 LREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQ-E 350

Query: 701 SAQSEQKNL 709
             Q EQ+ L
Sbjct: 351 RRQEEQERL 359



 Score = 30.0 bits (66), Expect = 8.7
 Identities = 14/54 (25%), Positives = 34/54 (62%), Gaps = 1/54 (1%)

Query: 656 QKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNL 709
           ++ L E +E+L  Q +R  + ++R  ++++ + E++ ERL+E+ E    +++ L
Sbjct: 268 EERLREQEERLHEQEERLCEQEERLREQEERLCEQE-ERLREQEERLCEQEERL 320


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score = 33.9 bits (76), Expect = 0.60
 Identities = 17/64 (26%), Positives = 38/64 (59%), Gaps = 1/64 (1%)

Query: 646 RKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSE 705
           R+  + + + ++ L E +E+L  Q +R  + ++R  ++++  L EQ ERL+E+ E    +
Sbjct: 195 RRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEER-LREQEERLREQEERLHEQ 253

Query: 706 QKNL 709
           ++ L
Sbjct: 254 EERL 257



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 17/65 (26%), Positives = 38/65 (58%), Gaps = 1/65 (1%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQS 704
           +R+  + + + ++ L E +E+L  Q +R  + ++R  ++++  L EQ ERL E+ E    
Sbjct: 201 LREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEER-LREQEERLHEQEERLCE 259

Query: 705 EQKNL 709
           +++ L
Sbjct: 260 QEERL 264



 Score = 30.0 bits (66), Expect = 8.7
 Identities = 18/69 (26%), Positives = 39/69 (56%), Gaps = 5/69 (7%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRK----DGVLEEQIERLQEKVE 700
           +R+  + + + ++ L E +E+L  Q +R  + ++R  +++       L E++E+L E+ E
Sbjct: 236 LREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQ-E 294

Query: 701 SAQSEQKNL 709
             Q EQ+ L
Sbjct: 295 RRQEEQERL 303


>gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 2 [Homo sapiens]
          Length = 595

 Score = 33.9 bits (76), Expect = 0.60
 Identities = 22/68 (32%), Positives = 41/68 (60%), Gaps = 5/68 (7%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGV-LEEQIERLQEKV---- 699
           IR+  + + K ++ L+E  EKL +  K +S  ++ +++ K  + LE+Q++ LQEK+    
Sbjct: 335 IREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVK 394

Query: 700 ESAQSEQK 707
           E+  S QK
Sbjct: 395 ETETSAQK 402


>gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 2 [Homo sapiens]
          Length = 595

 Score = 33.9 bits (76), Expect = 0.60
 Identities = 22/68 (32%), Positives = 41/68 (60%), Gaps = 5/68 (7%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGV-LEEQIERLQEKV---- 699
           IR+  + + K ++ L+E  EKL +  K +S  ++ +++ K  + LE+Q++ LQEK+    
Sbjct: 335 IREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVK 394

Query: 700 ESAQSEQK 707
           E+  S QK
Sbjct: 395 ETETSAQK 402


>gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 595

 Score = 33.9 bits (76), Expect = 0.60
 Identities = 22/68 (32%), Positives = 41/68 (60%), Gaps = 5/68 (7%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGV-LEEQIERLQEKV---- 699
           IR+  + + K ++ L+E  EKL +  K +S  ++ +++ K  + LE+Q++ LQEK+    
Sbjct: 335 IREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVK 394

Query: 700 ESAQSEQK 707
           E+  S QK
Sbjct: 395 ETETSAQK 402


>gi|169208016 PREDICTED: similar to golgi autoantigen, golgin
           subfamily a, 8E isoform 1 [Homo sapiens]
          Length = 594

 Score = 33.9 bits (76), Expect = 0.60
 Identities = 22/68 (32%), Positives = 41/68 (60%), Gaps = 5/68 (7%)

Query: 645 IRKMNKHVLKIQKELEEAKEKLARQHKRRSDDDDRSSDRKDGV-LEEQIERLQEKV---- 699
           IR+  + + K ++ L+E  EKL +  K +S  ++ +++ K  + LE+Q++ LQEK+    
Sbjct: 334 IREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVK 393

Query: 700 ESAQSEQK 707
           E+  S QK
Sbjct: 394 ETETSAQK 401


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,708,376
Number of Sequences: 37866
Number of extensions: 1486079
Number of successful extensions: 6640
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 149
Number of HSP's that attempted gapping in prelim test: 6125
Number of HSP's gapped (non-prelim): 731
length of query: 790
length of database: 18,247,518
effective HSP length: 110
effective length of query: 680
effective length of database: 14,082,258
effective search space: 9575935440
effective search space used: 9575935440
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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