Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 13027644

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13027644 small nuclear ribonucleoprotein polypeptide N [Homo
sapiens]
         (240 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13027650 small nuclear ribonucleoprotein polypeptide N [Homo ...   504   e-143
gi|13027648 small nuclear ribonucleoprotein polypeptide N [Homo ...   504   e-143
gi|13027646 small nuclear ribonucleoprotein polypeptide N [Homo ...   504   e-143
gi|13027644 small nuclear ribonucleoprotein polypeptide N [Homo ...   504   e-143
gi|4507135 small nuclear ribonucleoprotein polypeptide N [Homo s...   504   e-143
gi|38150007 small nuclear ribonucleoprotein polypeptide B/B' iso...   481   e-136
gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isof...   454   e-128
gi|169216044 PREDICTED: similar to hCG2041320 [Homo sapiens]          240   9e-64
gi|169215838 PREDICTED: similar to hCG2041320 [Homo sapiens]          240   9e-64
gi|169215637 PREDICTED: similar to hCG2041320 [Homo sapiens]          240   9e-64
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               77   2e-14
gi|160707881 formin 2 [Homo sapiens]                                   74   1e-13
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    73   2e-13
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     72   3e-13
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                71   7e-13
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 71   1e-12
gi|4557317 annexin A11 [Homo sapiens]                                  68   6e-12
gi|22165433 annexin A11 [Homo sapiens]                                 68   6e-12
gi|22165431 annexin A11 [Homo sapiens]                                 68   6e-12
gi|157168329 formin 1 [Homo sapiens]                                   67   1e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni...    67   2e-11
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    65   4e-11
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    65   4e-11
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    65   4e-11
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    65   4e-11
gi|210032580 SET domain containing 1B [Homo sapiens]                   65   4e-11
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    65   4e-11
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 64   9e-11
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    64   1e-10
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    64   2e-10

>gi|13027650 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  504 bits (1298), Expect = e-143
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
           RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240


>gi|13027648 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  504 bits (1298), Expect = e-143
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
           RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240


>gi|13027646 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  504 bits (1298), Expect = e-143
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
           RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240


>gi|13027644 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  504 bits (1298), Expect = e-143
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
           RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240


>gi|4507135 small nuclear ribonucleoprotein polypeptide N [Homo
           sapiens]
          Length = 240

 Score =  504 bits (1298), Expect = e-143
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180

Query: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
           RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP
Sbjct: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240


>gi|38150007 small nuclear ribonucleoprotein polypeptide B/B'
           isoform B' [Homo sapiens]
          Length = 240

 Score =  481 bits (1237), Expect = e-136
 Identities = 223/240 (92%), Positives = 233/240 (97%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180

Query: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RGPPPPGMRPPRP
Sbjct: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP 240


>gi|4507125 small nuclear ribonucleoprotein polypeptide B/B' isoform
           B [Homo sapiens]
          Length = 231

 Score =  454 bits (1167), Expect = e-128
 Identities = 212/229 (92%), Positives = 222/229 (96%)

Query: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPE 60
           MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKN+KQ E
Sbjct: 1   MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAE 60

Query: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPI 120
           REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG+GRAAGRG+PAGVP+
Sbjct: 61  REEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPM 120

Query: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVG 180
           PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA AATASIAGAPTQYPPGRG PPPP+G
Sbjct: 121 PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMG 180

Query: 181 RATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRG 229
           R  PPPG+M PPPGMRPPMGPP+G+PP RGTP+GMPPPGMRPPPPG+RG
Sbjct: 181 RGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRG 229


>gi|169216044 PREDICTED: similar to hCG2041320 [Homo sapiens]
          Length = 318

 Score =  240 bits (612), Expect = 9e-64
 Identities = 118/141 (83%), Positives = 124/141 (87%)

Query: 7   SKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRV 66
           +++ QHIDYRM+CILQ+G IF G FKAFDKH+NLILCDCDEFRKIKPKN KQPE EEK  
Sbjct: 152 ARLQQHIDYRMKCILQEGTIFFGIFKAFDKHVNLILCDCDEFRKIKPKNVKQPELEEKHF 211

Query: 67  LGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAG 126
            GLVLL GENLVSMTVEG PPK TGIARVPLAGAAGGPGV RAAGRGV AGVPIPQAP G
Sbjct: 212 WGLVLLHGENLVSMTVEGLPPKYTGIARVPLAGAAGGPGVVRAAGRGVSAGVPIPQAPGG 271

Query: 127 LAGPVRGVGGPSQQVMTPQGR 147
           LAGPV GVGGPSQQVMTPQ R
Sbjct: 272 LAGPVPGVGGPSQQVMTPQRR 292



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 4/67 (5%)

Query: 173 GTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPP 232
           G PP   G A  P    A  PG+    G  +    + G PI   P G+  P PG+ GP  
Sbjct: 229 GLPPKYTGIARVPLAGAAGGPGVVRAAGRGV----SAGVPIPQAPGGLAGPVPGVGGPSQ 284

Query: 233 PGMRPPR 239
             M P R
Sbjct: 285 QVMTPQR 291


>gi|169215838 PREDICTED: similar to hCG2041320 [Homo sapiens]
          Length = 318

 Score =  240 bits (612), Expect = 9e-64
 Identities = 118/141 (83%), Positives = 124/141 (87%)

Query: 7   SKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRV 66
           +++ QHIDYRM+CILQ+G IF G FKAFDKH+NLILCDCDEFRKIKPKN KQPE EEK  
Sbjct: 152 ARLQQHIDYRMKCILQEGTIFFGIFKAFDKHVNLILCDCDEFRKIKPKNVKQPELEEKHF 211

Query: 67  LGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAG 126
            GLVLL GENLVSMTVEG PPK TGIARVPLAGAAGGPGV RAAGRGV AGVPIPQAP G
Sbjct: 212 WGLVLLHGENLVSMTVEGLPPKYTGIARVPLAGAAGGPGVVRAAGRGVSAGVPIPQAPGG 271

Query: 127 LAGPVRGVGGPSQQVMTPQGR 147
           LAGPV GVGGPSQQVMTPQ R
Sbjct: 272 LAGPVPGVGGPSQQVMTPQRR 292



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 4/67 (5%)

Query: 173 GTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPP 232
           G PP   G A  P    A  PG+    G  +    + G PI   P G+  P PG+ GP  
Sbjct: 229 GLPPKYTGIARVPLAGAAGGPGVVRAAGRGV----SAGVPIPQAPGGLAGPVPGVGGPSQ 284

Query: 233 PGMRPPR 239
             M P R
Sbjct: 285 QVMTPQR 291


>gi|169215637 PREDICTED: similar to hCG2041320 [Homo sapiens]
          Length = 318

 Score =  240 bits (612), Expect = 9e-64
 Identities = 118/141 (83%), Positives = 124/141 (87%)

Query: 7   SKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRV 66
           +++ QHIDYRM+CILQ+G IF G FKAFDKH+NLILCDCDEFRKIKPKN KQPE EEK  
Sbjct: 152 ARLQQHIDYRMKCILQEGTIFFGIFKAFDKHVNLILCDCDEFRKIKPKNVKQPELEEKHF 211

Query: 67  LGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAG 126
            GLVLL GENLVSMTVEG PPK TGIARVPLAGAAGGPGV RAAGRGV AGVPIPQAP G
Sbjct: 212 WGLVLLHGENLVSMTVEGLPPKYTGIARVPLAGAAGGPGVVRAAGRGVSAGVPIPQAPGG 271

Query: 127 LAGPVRGVGGPSQQVMTPQGR 147
           LAGPV GVGGPSQQVMTPQ R
Sbjct: 272 LAGPVPGVGGPSQQVMTPQRR 292



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 4/67 (5%)

Query: 173 GTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPP 232
           G PP   G A  P    A  PG+    G  +    + G PI   P G+  P PG+ GP  
Sbjct: 229 GLPPKYTGIARVPLAGAAGGPGVVRAAGRGV----SAGVPIPQAPGGLAGPVPGVGGPSQ 284

Query: 233 PGMRPPR 239
             M P R
Sbjct: 285 QVMTPQR 291


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 54/149 (36%), Positives = 67/149 (44%), Gaps = 20/149 (13%)

Query: 101 AGGPGVGRAAG---RGVPAGVPIPQA-----PAGLAGPVRGVGGPSQQVMTPQGRGTVAA 152
           AG PGV R       G+P   P+P++     P GL  P     GP+     P G      
Sbjct: 225 AGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPA-----PSGPPGPPQ 279

Query: 153 AAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGL-PPARGT 211
               A      AP  +PP  G  PP  G   P PG+  P PG+ PP     G+ PPA G 
Sbjct: 280 LPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTS---GVHPPAPG- 335

Query: 212 PIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
            +  P PG+ PP PG+  PP PG+ PP P
Sbjct: 336 -VHPPAPGVHPPAPGVH-PPAPGVHPPAP 362



 Score = 67.8 bits (164), Expect = 8e-12
 Identities = 55/173 (31%), Positives = 72/173 (41%), Gaps = 24/173 (13%)

Query: 85  PPPKDTGIARVPLAGAA--GGPGVGRAA--GRGVPAGVPIPQAPA-GLAGPVRGVGGPSQ 139
           PPP    +  +P  G A  G PG  +      GV    P+   PA G+  P  GV  P+ 
Sbjct: 254 PPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAP 313

Query: 140 QVMTPQGRGTVAAAAVAATASI-AGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPP 198
            V  P      A      T+ +   AP  +PP  G  PP  G   P PG+  P PG+ PP
Sbjct: 314 GVHPP------APGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPP 367

Query: 199 MGPPI-----GLPPA------RGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
               +     G+ PA      +   +  P PGM P  PG+  P PPG+ P  P
Sbjct: 368 PSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVH-PQPPGVHPSAP 419



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 45/130 (34%), Positives = 52/130 (40%), Gaps = 14/130 (10%)

Query: 109 AAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAA---VAATASIAGAP 165
           A G   PA    P AP G+  P  GV  P+  V  P   G    A     AA A    AP
Sbjct: 333 APGVHPPAPGVHPPAP-GVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAP 391

Query: 166 TQYPPGRGTPPPPVGRATPPPGIMAPPPGMRP-PMG---------PPIGLPPARGTPIGM 215
             +PP  G  P   G    PPG+    PG+ P P G         PP  +PP    P+  
Sbjct: 392 GVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPS 451

Query: 216 PPPGMRPPPP 225
             PG  PPPP
Sbjct: 452 EGPGNIPPPP 461



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 10/76 (13%)

Query: 175 PPPPVGRATPPPGIMAPPPGM------RPPMGPPIGLPPARGTPI-GMPPPG---MRPPP 224
           PP P      PPG+  PPP +      RPP+   +  PP  G P+  MPP G     PP 
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPG 276

Query: 225 PGIRGPPPPGMRPPRP 240
           P    PP PG+ PP P
Sbjct: 277 PPQLPPPAPGVHPPAP 292



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 36/102 (35%), Positives = 41/102 (40%), Gaps = 31/102 (30%)

Query: 169 PPGRGTPPPPVGRATP------------PPGIMAPPPGMRP-------------PMGPPI 203
           PP     PP V R  P            P  +  PPPG  P             P GPP 
Sbjct: 220 PPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQ 279

Query: 204 GLPPARG----TPIGMPP-PGMRPPPPGIRGPPPPGMRPPRP 240
             PPA G     P+  PP  G+ PP PG+  PP PG+ PP P
Sbjct: 280 LPPPAPGVHPPAPVVHPPASGVHPPAPGVH-PPAPGVHPPAP 320


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 65/178 (36%), Positives = 76/178 (42%), Gaps = 33/178 (18%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI  +P    AG P      G  +P   P+P A   L  P+ G G P    +  
Sbjct: 924  PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP- 982

Query: 145  QGRGTVAAAAVAATASIAGAPTQYP-PGRGTPPPPV--GRATPPP------GIMAPPP-- 193
             G G      +      AG P   P PG G PPPP   G   PPP      GI  PPP  
Sbjct: 983  -GAGIPPPPPLPG----AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037

Query: 194  --GMRPPMGPPI---GLPPARGTP-IGMPPPGMRPPPPGIRGPPPP-----GMRPPRP 240
              G+ PP  PP+   G+PP    P  G+PPP   PP PG   PPPP     G+ PP P
Sbjct: 1038 GAGIPPP--PPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPP 1090



 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 63/181 (34%), Positives = 75/181 (41%), Gaps = 28/181 (15%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P    AG P      G G+P   P+P A      P+ G G P    +  
Sbjct: 968  PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027

Query: 145  QG---RGTVAAAAVAATASIAGAPTQYPP---GRGTPPPPV--GRATPPP------GIMA 190
             G      +  A +     + GA    PP   G G PPPP   G   PPP      GI  
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087

Query: 191  PPP----GMRPPMG-PPIGLPPARGTP-IGMPPPGMRPPPPGIRGPPPP-----GMRPPR 239
            PPP    G+ PP   P +G+PP    P  G+PPP   PP PG   PPPP     G+ PP 
Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPP 1144

Query: 240  P 240
            P
Sbjct: 1145 P 1145



 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 67/186 (36%), Positives = 79/186 (42%), Gaps = 36/186 (19%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P    AG P      G G+P   P+P A      P+ GVG P    +  
Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP- 1114

Query: 145  QGRGTVAAAAVAATASIAGAPTQYP-PGRGTPPPP----VGRATPPP----GIMAPPP-- 193
             G G      +      AG P   P PG G PPPP    VG   PPP    GI  PPP  
Sbjct: 1115 -GAGIPPPPPLPG----AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP 1169

Query: 194  --GMRPPMG-PPIGLPPARGTP-IGMPPP------GMRPPPP--GIRGPP-------PPG 234
              G+ PP   P +G+PP    P +G+PPP      G+ PPPP  G+  PP       PPG
Sbjct: 1170 GAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPG 1229

Query: 235  MRPPRP 240
               P P
Sbjct: 1230 TGIPPP 1235



 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 64/178 (35%), Positives = 76/178 (42%), Gaps = 33/178 (18%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P    AG P      G G+P   P+P A      P+ G G P    +  
Sbjct: 957  PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP- 1015

Query: 145  QGRGTVAAAAVAATASIAGAPTQYP-PGRGTPPPPVGRATPPPGIMAPPP----GMRPPM 199
             G G      +      AG P   P PG G PPPP     P  GI  PPP    G+ PP 
Sbjct: 1016 -GAGIPPPPPLPG----AGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPP- 1066

Query: 200  GPPI---GLPPARGTP-IGMPPP------GMRPPP--PGIRGPPPP-----GMRPPRP 240
             PP+   G+PP    P  G+PPP      G+ PPP  PG+  PPPP     G+ PP P
Sbjct: 1067 -PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1123



 Score = 67.8 bits (164), Expect = 8e-12
 Identities = 58/169 (34%), Positives = 70/169 (41%), Gaps = 24/169 (14%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P    AG P      G G+P   P+P A      P+ G G P    +  
Sbjct: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1137

Query: 145  QG---RGTVAAAAVAATASIAGAPTQYPP---GRGTPPPP----VGRATPPP----GIMA 190
             G      +    +     + GA    PP   G G PPPP    VG   PPP    GI  
Sbjct: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP 1197

Query: 191  PPP----GMRPPMG-PPIGLPPARGTPIGMPPPGMRPPPP---GIRGPP 231
            PPP    G+ PP   P +G+PPA   P+  PPPG   PPP    + GPP
Sbjct: 1198 PPPLPGAGIPPPPPLPGMGIPPAPAPPL--PPPGTGIPPPPLLPVSGPP 1244



 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 61/180 (33%), Positives = 74/180 (41%), Gaps = 40/180 (22%)

Query: 77   LVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGG 136
            L S  +  PPP   G   +P       P      G G+P   P+P A      P+ G G 
Sbjct: 891  LPSTAIPQPPPLQ-GTEMLP-------PPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGI 942

Query: 137  PSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPP---GRGTPPPPVGRATPPPGIMAPPP 193
            P    +          AA+     + GA    PP   G G PPPP     P  GI  PPP
Sbjct: 943  PPPPPLP--------GAAIPPPPPLPGAGIPLPPPLPGAGIPPPP---PLPGAGIPPPPP 991

Query: 194  ----GMRPPMGPPI---GLPPARGTP-IGMPPPGMRPPPPGIRGPPPP-----GMRPPRP 240
                G+ PP  PP+   G+PP    P  G+PPP   PP PG   PPPP     G+ PP P
Sbjct: 992  LPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPP 1046



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 48/142 (33%), Positives = 57/142 (40%), Gaps = 10/142 (7%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    GI   P     G P      G G+P   P+P A      P+ GVG P    +  
Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP- 1191

Query: 145  QGRGTVAAAAVAATASIAGAPTQYP-PGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPI 203
             G G      +      AG P   P PG G PP P     PPPG   PPP + P  GPP+
Sbjct: 1192 -GVGIPPPPPLPG----AGIPPPPPLPGMGIPPAPAP-PLPPPGTGIPPPPLLPVSGPPL 1245

Query: 204  GLPPARGTPIGMPPP-GMRPPP 224
             LP    + +  P   G  PPP
Sbjct: 1246 -LPQVGSSTLPTPQVCGFLPPP 1266



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 49/162 (30%), Positives = 66/162 (40%), Gaps = 38/162 (23%)

Query: 114  VPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPP--- 170
            +P+  P+P   +  + P  G+  P    +      T+ + A+     + G     PP   
Sbjct: 855  IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP 914

Query: 171  --GRGT-PPPPV------------GRATPP----PGIMAPPPGMRP----PMGPPI---G 204
              G G  PPPP+            G   PP    PG   PPP   P    P+ PP+   G
Sbjct: 915  LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG 974

Query: 205  LPPARGTP-IGMPPPGMRPPPPGIRGPPPP-----GMRPPRP 240
            +PP    P  G+PPP   PP PG   PPPP     G+ PP P
Sbjct: 975  IPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPP 1013


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 64/185 (34%), Positives = 68/185 (36%), Gaps = 47/185 (25%)

Query: 86  PPKDTGIARVPLAGAAGG------PGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQ 139
           PP  +  A  P  G   G      PG  R  G   P G P P  PAG   P   +G P  
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP-PPFPAGQTPPRPPLGPP-- 244

Query: 140 QVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGT-PPPPV----------GRATPPPGI 188
                   G            +   P   PP RG  PPPPV               PPG 
Sbjct: 245 --------GPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296

Query: 189 MAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPP-PPGIRGPP------------PPGM 235
             P PG  PP GPP   PP +G P   PPPG  PP PPG  GPP            PPG 
Sbjct: 297 PPPVPGYGPPPGPP---PPQQGPP---PPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGA 350

Query: 236 RPPRP 240
            PP P
Sbjct: 351 PPPAP 355



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 63/174 (36%), Positives = 70/174 (40%), Gaps = 32/174 (18%)

Query: 85  PPPKDTGIA--RVPLAGAAGGPGVGRAAGRGVPAGVPIPQA--PAGLAGPVRGVGGPSQQ 140
           PPP   G    R PL G  G PG         P G P P    P  LAGP      P   
Sbjct: 227 PPPFPAGQTPPRPPL-GPPGPPG---------PPGPPPPGQVLPPPLAGPPNRGDRPPPP 276

Query: 141 VMTPQ---GRGTVAAAAVAATASIAG--APTQYPPGRGTPPPPVGRATP-PPGIMAPPPG 194
           V+ P    G+  +          + G   P   PP +  PPPP G   P PPG + PP  
Sbjct: 277 VLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT 336

Query: 195 MRPP---MGPPIGLPP--ARGTPIGMPPP---GMRPPPPGIRGPPP--PGMRPP 238
           + PP    GPP G PP      P   PPP   GM  P    RGPPP  P  RPP
Sbjct: 337 LAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGM--PTSDSRGPPPTDPYGRPP 388


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 62/204 (30%), Positives = 75/204 (36%), Gaps = 39/204 (19%)

Query: 49  RKIKPKNAKQPEREEKRVLGLVLLRGENLVSM--------TVEGPPPKDTGIARVPLAGA 100
           R ++ ++  +PER    +  L+  R    VS              PP+       P    
Sbjct: 56  RMVRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAP 115

Query: 101 AGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATAS 160
            G P    AA        P P AP   A P R                   AAA AATA 
Sbjct: 116 RGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAP----------------RAAAAAATAP 159

Query: 161 IAGAPTQYPPGRGTPPPPVGRATP---PPGIMAPPPGMRPPMGPPIGLPPA---RGTPIG 214
            +  P Q       P P   RA P   PP   A PP + PP GP    PPA   R  P  
Sbjct: 160 PSPGPAQ-------PGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPP-- 210

Query: 215 MPPPGMRPPPPGIRGPPPPGMRPP 238
           +PPP   P PP  + PPPP  +PP
Sbjct: 211 LPPPPQPPAPPQQQQPPPPQPQPP 234



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 39/120 (32%), Positives = 45/120 (37%), Gaps = 24/120 (20%)

Query: 137 PSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATP------------ 184
           P ++  TP         A AA A+ A  PT  PP    PP PV  A P            
Sbjct: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPP---PPPAPVAAAAPARAPRAAAAAAT 157

Query: 185 -PPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGM---RPPRP 240
            PP      PG R     P+  PP    P    PP + PP  G R  PPP +    PP P
Sbjct: 158 APPSPGPAQPGPRAQRAAPLAAPP----PAPAAPPAVAPPA-GPRRAPPPAVAAREPPLP 212



 Score = 35.8 bits (81), Expect = 0.034
 Identities = 32/113 (28%), Positives = 35/113 (30%), Gaps = 35/113 (30%)

Query: 163 GAPTQYPPG--RGTPPPPVGRATPPPGIMAPPPG-------------------MRPPMGP 201
           GA    PP   RG P      A PP     PPP                      P  GP
Sbjct: 105 GATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGP 164

Query: 202 PIGLPPA-RGTPIGMPPPG-------------MRPPPPGIRGPPPPGMRPPRP 240
               P A R  P+  PPP               R PPP +    PP   PP+P
Sbjct: 165 AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQP 217



 Score = 35.8 bits (81), Expect = 0.034
 Identities = 37/120 (30%), Positives = 41/120 (34%), Gaps = 13/120 (10%)

Query: 85  PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAP-----AGLAGPVRGVGGPSQ 139
           PPP     A V  A  A  P    AA    P+  P    P     A LA P      P  
Sbjct: 135 PPP-----APVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPA 189

Query: 140 QVMTPQGRGTVAAAAVAATASIAGAPTQ--YPPGRGTPPPPVGRATPPPGIMAPPPGMRP 197
            V  P G       AVAA       P Q   PP +  PPPP  +  P  G +      RP
Sbjct: 190 -VAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARP 248



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 18/44 (40%), Positives = 20/44 (45%), Gaps = 2/44 (4%)

Query: 180 GRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPP 223
           G A+   G  +P P   PP  P   LP A GTP G PP     P
Sbjct: 415 GTASVATGPDSPSPVPLPPGKP--ALPGADGTPFGCPPGRKEKP 456


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 71.2 bits (173), Expect = 7e-13
 Identities = 65/179 (36%), Positives = 70/179 (39%), Gaps = 54/179 (30%)

Query: 85  PPPKDTGIAR--VPLAGA--AGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQ 140
           PPP   G A    P AG   AG PG G +         P P  P G+  P     G SQ 
Sbjct: 263 PPPMPPGAAGHGPPSAGTPGAGHPGHGHSH--------PHPFPPGGMPHP-----GMSQM 309

Query: 141 VMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIM--APPPGMRPP 198
            +   G   +            G P   PPG G  PPP     PPPG+    PPP   PP
Sbjct: 310 QLAHHGPHGL------------GHPHAGPPGSGGQPPP----RPPPGMPHPGPPPMGMPP 353

Query: 199 MGPPIGLPPARGTPIGMPPPGMRPPPP-----GIRGPP------------PPGMRPPRP 240
            GPP G P   G P  MPP GMR PPP     G  GPP            PP    PRP
Sbjct: 354 RGPPFGSP--MGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRP 410



 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 56/157 (35%), Positives = 63/157 (40%), Gaps = 35/157 (22%)

Query: 113 GVPAGVPIPQAPAGLAG--------PVRGVGGPSQQVMTPQGRGTVAAAAVAATASI--- 161
           G+P  +P P  P G AG        P  G  G       P   G +    ++        
Sbjct: 256 GIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHG 315

Query: 162 ---AGAPTQYPPGRGTPPPPVGRATPPPGI--MAPPPGMRPPMGPPIGLPPARGTPIGMP 216
               G P   PPG G  PPP     PPPG+    PPP   PP GPP G P   G P  MP
Sbjct: 316 PHGLGHPHAGPPGSGGQPPP----RPPPGMPHPGPPPMGMPPRGPPFGSP--MGHPGPMP 369

Query: 217 PPGMRPPPP-----GIRGPPPP--------GMRPPRP 240
           P GMR PPP     G  GPP P         + PPRP
Sbjct: 370 PHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRP 406



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 9/97 (9%)

Query: 148 GTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMA-----PPPGMRPPMGPP 202
           G+ A   +AA   ++ A   +      PPPP   + P P + +     PPPGM PP   P
Sbjct: 188 GSAAERLLAAQNPLSQADRPHQLFADAPPPP---SAPNPVVSSLGSGLPPPGMPPPGSFP 244

Query: 203 IGLPPARGTPIGMPPPGMRPP-PPGIRGPPPPGMRPP 238
             +PP    P G+PP    PP PPG  G  PP    P
Sbjct: 245 PPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTP 281



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 37/83 (44%), Positives = 41/83 (49%), Gaps = 15/83 (18%)

Query: 162 AGAPTQYPPGRGTPPPPVGRATPPPGIMAP--PPGMRPPMGPPIGL---PPARGTP-IGM 215
           +G P    P  G+ PPPV    PPPG + P  PP M PP  PP      PP+ GTP  G 
Sbjct: 230 SGLPPPGMPPPGSFPPPV----PPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGH 285

Query: 216 PPPGMRPP---PPGIRGPPPPGM 235
           P  G   P   PPG  G P PGM
Sbjct: 286 PGHGHSHPHPFPPG--GMPHPGM 306



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 178 PVGRATPPPGIMA---PPPGMRPPMGPPIG--LPPARGTPIGMPPPGMRPPPPGIRGPPP 232
           P+ +A  P  + A   PPP    P+   +G  LPP       MPPPG  PPP    G  P
Sbjct: 200 PLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPG-----MPPPGSFPPPVPPPGALP 254

Query: 233 PGMRPPRP 240
           PG+ P  P
Sbjct: 255 PGIPPAMP 262


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 39/81 (48%), Positives = 44/81 (54%), Gaps = 4/81 (4%)

Query: 163 GAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPA--RGTPIGMPP-PG 219
           G PT  PPG     PP  R    PG+  P P + PP GPP G PP    G P G+PP P 
Sbjct: 425 GPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPP-GPPPGRPPGPPPGPPPGLPPGPP 483

Query: 220 MRPPPPGIRGPPPPGMRPPRP 240
            R PPP +  P PPG+ PPRP
Sbjct: 484 PRGPPPRLPPPAPPGIPPPRP 504



 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 60/161 (37%), Positives = 69/161 (42%), Gaps = 46/161 (28%)

Query: 84  GPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGP-VRGVGGPSQQVM 142
           GPPP   G    P     G P        G+P G P P AP  L  P + G+ GP  +++
Sbjct: 409 GPPP--LGPPPAPPLRPPGPP-------TGLPPGPP-PGAPPFLRPPGMPGLRGPLPRLL 458

Query: 143 TPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP 202
            P                        PPGR   PPP     PPPG+   PPG  PP GPP
Sbjct: 459 PPGP----------------------PPGRPPGPPP----GPPPGL---PPGP-PPRGPP 488

Query: 203 IGLPPARGTPIGMPPPG---MRPPPPGIRGPPPPGMRPPRP 240
             LPP    P G+PPP    MRPP     GP PPG+ PP P
Sbjct: 489 PRLPPP--APPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAP 527



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 12/54 (22%)

Query: 191 PPPGMRPPM--------GPP---IGLPPARGTPIGMPPPGMRPPPPGIRGPPPP 233
           P PG +PP         GPP   + + P  G  +   PPG +PP P   GPPPP
Sbjct: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPP-PGPPPP 209



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 13/98 (13%)

Query: 118 VPIPQAPAGLAG------PVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPG 171
           +P+P  P   +       P+ G   PS  ++           AV+    +     + PPG
Sbjct: 139 IPLPDMPHAPSNILIQDIPLPGAQPPS--ILKKTSAYGPPTRAVSILPLLGHGVPRLPPG 196

Query: 172 RGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPAR 209
           R  P PP G   PPP  +    G +  +G  + LPP R
Sbjct: 197 RKPPGPPPG---PPPPQVVQMYGRK--VGFALDLPPRR 229


>gi|4557317 annexin A11 [Homo sapiens]
          Length = 505

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 59/163 (36%), Positives = 65/163 (39%), Gaps = 41/163 (25%)

Query: 115 PAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVA--------------AAAVAATAS 160
           P G P P AP G  GP  G   P    M P G   VA              AA ++ T  
Sbjct: 10  PGGYP-PAAPGG--GPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFG 66

Query: 161 IAGAPTQYP--PGRGTPP--------PPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARG 210
            A  P  YP  PG G PP        PP  +   PP  M PPPG  PP   P   PP  G
Sbjct: 67  GANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMP-SYPPYPG 125

Query: 211 TPI---GMPPPGMRP-------PPPGIRGPPP---PGMRPPRP 240
            P+    MPPPG +P       PP    G PP   PG + P P
Sbjct: 126 APVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVP 168



 Score = 34.3 bits (77), Expect = 0.099
 Identities = 31/115 (26%), Positives = 32/115 (27%), Gaps = 47/115 (40%)

Query: 168 YPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGL---------------------- 205
           YPP  G  PP      P  G   PPP    P  PPIGL                      
Sbjct: 6   YPPPPGGYPPAAPGGGPWGGAAYPPP----PSMPPIGLDNVATYAGQFNQDYLSGMAANM 61

Query: 206 ---------------------PPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPR 239
                                PP      G PP   +P PP    PPP G  P R
Sbjct: 62  SGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSR 116


>gi|22165433 annexin A11 [Homo sapiens]
          Length = 505

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 59/163 (36%), Positives = 65/163 (39%), Gaps = 41/163 (25%)

Query: 115 PAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVA--------------AAAVAATAS 160
           P G P P AP G  GP  G   P    M P G   VA              AA ++ T  
Sbjct: 10  PGGYP-PAAPGG--GPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFG 66

Query: 161 IAGAPTQYP--PGRGTPP--------PPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARG 210
            A  P  YP  PG G PP        PP  +   PP  M PPPG  PP   P   PP  G
Sbjct: 67  GANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMP-SYPPYPG 125

Query: 211 TPI---GMPPPGMRP-------PPPGIRGPPP---PGMRPPRP 240
            P+    MPPPG +P       PP    G PP   PG + P P
Sbjct: 126 APVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVP 168



 Score = 34.3 bits (77), Expect = 0.099
 Identities = 31/115 (26%), Positives = 32/115 (27%), Gaps = 47/115 (40%)

Query: 168 YPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGL---------------------- 205
           YPP  G  PP      P  G   PPP    P  PPIGL                      
Sbjct: 6   YPPPPGGYPPAAPGGGPWGGAAYPPP----PSMPPIGLDNVATYAGQFNQDYLSGMAANM 61

Query: 206 ---------------------PPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPR 239
                                PP      G PP   +P PP    PPP G  P R
Sbjct: 62  SGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSR 116


>gi|22165431 annexin A11 [Homo sapiens]
          Length = 505

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 59/163 (36%), Positives = 65/163 (39%), Gaps = 41/163 (25%)

Query: 115 PAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVA--------------AAAVAATAS 160
           P G P P AP G  GP  G   P    M P G   VA              AA ++ T  
Sbjct: 10  PGGYP-PAAPGG--GPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFG 66

Query: 161 IAGAPTQYP--PGRGTPP--------PPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARG 210
            A  P  YP  PG G PP        PP  +   PP  M PPPG  PP   P   PP  G
Sbjct: 67  GANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMP-SYPPYPG 125

Query: 211 TPI---GMPPPGMRP-------PPPGIRGPPP---PGMRPPRP 240
            P+    MPPPG +P       PP    G PP   PG + P P
Sbjct: 126 APVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVP 168



 Score = 34.3 bits (77), Expect = 0.099
 Identities = 31/115 (26%), Positives = 32/115 (27%), Gaps = 47/115 (40%)

Query: 168 YPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGL---------------------- 205
           YPP  G  PP      P  G   PPP    P  PPIGL                      
Sbjct: 6   YPPPPGGYPPAAPGGGPWGGAAYPPP----PSMPPIGLDNVATYAGQFNQDYLSGMAANM 61

Query: 206 ---------------------PPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPR 239
                                PP      G PP   +P PP    PPP G  P R
Sbjct: 62  SGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSR 116


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 55/162 (33%), Positives = 68/162 (41%), Gaps = 38/162 (23%)

Query: 76  NLVSMTVEGPPP--KDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRG 133
           N+ S++   PP   KD   A  P+ G A      + A    PA +P P            
Sbjct: 611 NISSLSQLSPPNDHKDIHAALQPMEGMASNQ---QKALPPPPASIPPPPP---------- 657

Query: 134 VGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPP 193
                     P G G+++ A      S AG P   PP    PPPP+    PPP    PPP
Sbjct: 658 ---------LPSGLGSLSPAPPMPPVS-AGPPLPPPP---PPPPPL----PPPSSAGPPP 700

Query: 194 GMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGM 235
              PP  PP+   PA   P G PP    PPPPG+  PPPPG+
Sbjct: 701 ---PPPPPPLPNSPAPPNPGGPPPA---PPPPGLAPPPPPGL 736



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 34/87 (39%), Positives = 38/87 (43%), Gaps = 15/87 (17%)

Query: 169 PPGRGTPPPP--------VGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPP-- 218
           PP    PPPP        +  A P P + A PP   PP  PP   PP+   P   PPP  
Sbjct: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPP 706

Query: 219 ---GMRPPPPG--IRGPPPPGMRPPRP 240
                 PP PG     PPPPG+ PP P
Sbjct: 707 LPNSPAPPNPGGPPPAPPPPGLAPPPP 733


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 63/196 (32%), Positives = 76/196 (38%), Gaps = 52/196 (26%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRG---VPAGVPIPQAPAGLA-GPVRGVGGPSQQ 140
            PP    G+A  P  GA   P     + +G    P+    P  PA     P  G+  PS  
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS-- 1213

Query: 141  VMTPQGRGTVAAAAVA------ATASIAGAPTQ-------------YPPGRGTPPPPV-- 179
               P+G  T  AA         AT S  GAPT               PP +G P PP   
Sbjct: 1214 ---PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270

Query: 180  ------GRATPP------PGIMAPP-----PGMRPPMG---PPIGLPPA-RGTPIGMPPP 218
                  G ATPP      P ++ PP     P   PP G   PP   PP+ +G+P G PPP
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP-GTPPP 1329

Query: 219  GMRPPPPGIRGPPPPG 234
               P PP +  P P G
Sbjct: 1330 KGAPTPPAVTPPSPKG 1345



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 53/179 (29%), Positives = 66/179 (36%), Gaps = 21/179 (11%)

Query: 82   VEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQ-AP----AGLAGPVRGVGG 136
            V  P PK +  A     GA+  P     + +G PA  P+P+ AP    A L  P  G   
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073

Query: 137  PSQQ-VMTPQGRGTVAAAAVAATASIAGAPTQ-------------YPPGRGTPPPPVGRA 182
            PS +   TP      +     AT S  GAP                PP +G P  P    
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133

Query: 183  TPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPP-GMRPPRP 240
              P G +A PP    P   P   PP+    +  PPP   P  P    P P  G+  P P
Sbjct: 1134 PSPKGGLATPPPKGAPT-TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSP 1191



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 47/157 (29%), Positives = 56/157 (35%), Gaps = 9/157 (5%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    G+A     GA   P     + +G PA  P   AP   A     + G    + TP
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG---LATP 1281

Query: 145  QGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIG 204
              +G     AV    S  G P   PP +G P PP      P G    PP    P  P + 
Sbjct: 1282 PHKGA-PNPAVVTPPSPKGGPATSPP-KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339

Query: 205  LPPARGTPI--GMPPPGMRPP--PPGIRGPPPPGMRP 237
             P  +GTP      P     P  P    GP PP   P
Sbjct: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 54/175 (30%), Positives = 65/175 (37%), Gaps = 30/175 (17%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPA-----GVPIPQAPAGLAGPVRGVGGPSQ 139
            P PK  G A   L GA   P     + +G PA     G P+P A    A P    GG   
Sbjct: 1065 PSPKG-GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA----ATPPSPKGG--- 1116

Query: 140  QVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPM 199
             + TP  +G     A    +   G  T  PP +G P  P      P G +A PP    P 
Sbjct: 1117 -LATPPHKGAPTTPAATPPSPKGGLAT--PPPKGAPTTPAATPPSPKGGLATPPPKGAPT 1173

Query: 200  GPPIGLPPARG-----TPIGMP-PPGMRPPPP--GIRGPPP------PGMRPPRP 240
             P    P  +G     +P G P  P   PP P  G+  P P      P   PP P
Sbjct: 1174 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 52/185 (28%), Positives = 65/185 (35%), Gaps = 22/185 (11%)

Query: 68   GLVLLRGENLVSMTVEGPPPKDTGIARVP-----LAGAAGGPGVGRA--AGRGVPA---- 116
            G+ L   E      V  P PK+      P     L+  +  P   RA  A +G+PA    
Sbjct: 877  GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936

Query: 117  -GVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTP 175
             G P P A    A P    GGP+    TP  +      A    +   G  T  P  +G P
Sbjct: 937  KGAPTPPA----ATPPSPKGGPA----TPSPKWAPTPPAATPPSPKGGPATPSP--KGAP 986

Query: 176  PPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGM 235
             PP      P G  A P     P  P +  P  +G+P   P P     PP    P P G 
Sbjct: 987  TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046

Query: 236  RPPRP 240
                P
Sbjct: 1047 PAATP 1051



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 57/173 (32%), Positives = 66/173 (38%), Gaps = 28/173 (16%)

Query: 84   GPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMT 143
            GP       A  P A     P  G A     P G P P A    A P    GGP+    T
Sbjct: 953  GPATPSPKWAPTPPAATPPSPKGGPATPS--PKGAPTPPA----ATPPSPKGGPA----T 1002

Query: 144  PQGRGTVAAAAVAATASIAGAP--TQYPPGRGTPP---PPVGRATP-----PPGIMAPPP 193
            P  +G     AV    S  G+P  T +P G  TPP   PP  + +P     P G    P 
Sbjct: 1003 PSPKGAPTPPAVTPP-SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA 1061

Query: 194  GMRP-PMGPPIGLPPARG--TPIGMPPPGMR--PPPPGIRGPP-PPGMRPPRP 240
               P P G P   P  +G  TP    PP  +  P  P  +G P PP   PP P
Sbjct: 1062 ATLPSPKGGP-ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113



 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 44/162 (27%), Positives = 53/162 (32%), Gaps = 25/162 (15%)

Query: 102  GGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVG---------GPSQQVMTPQGRGTVAA 152
            GGP      G  +P     P    GLA P               P   + TP  +G    
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151

Query: 153  AAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARG-- 210
             A    +   G  T  PP +G P  P      P G +A P     P  P    P  +G  
Sbjct: 1152 PAATPPSPKGGLAT--PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1209

Query: 211  ---TPIGMP-PPGMRPPPP--GIRGPPP------PGMRPPRP 240
               +P G P  P   PP P  G+  P P      P   PP P
Sbjct: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1251



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 59/216 (27%), Positives = 76/216 (35%), Gaps = 28/216 (12%)

Query: 53   PKNAKQPEREEKRVL--GLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAA 110
            PK A  P       L  GL     +   +  V  PP    G A  P  GA   P     +
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319

Query: 111  GRGVPAGVPIPQAPAGLA-GPVRGVGGPSQQVMTPQGRGTVAAAAV-------AATASIA 162
             +G P   P   AP   A  P    G P+    TP  +G     +        AAT S  
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379

Query: 163  GAPTQYPPG--RGTP-PPPVGRATPPPGI-MAPPPGMRPPMGPPIGLPPARG--TPIGMP 216
            G P   PP   RG   P P G  T P  I ++P      P+       P++G  TP  + 
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439

Query: 217  PPGMRPPP-----------PGIRGPPP-PGMRPPRP 240
            P  ++  P           P  +G P  P + PP P
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSP 1475



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 38/147 (25%), Positives = 48/147 (32%), Gaps = 11/147 (7%)

Query: 104  PGVGRAAGRGVPAGVPIPQAPAGLAG-PVRGVGGPSQQVMTPQGRG-----TVAAAAVAA 157
            P   + A    P   P   AP G    P      P +   TP  R      T    +   
Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538

Query: 158  TASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPA-RGTPIG-- 214
             A++A      PP    P P    A P P      P  +    PP   P   +G P    
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598

Query: 215  -MPPPGMRPPPPGIRGPPPPGMRPPRP 240
             + PP +  P P    P PP + PP P
Sbjct: 1599 LLIPPAVTSPSPK-EAPTPPAVTPPSP 1624



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 42/170 (24%), Positives = 64/170 (37%), Gaps = 27/170 (15%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVP-----IPQAPAGLAGPVRGVGGP 137
            E P PK    +  P    A    +G      +PA +P     +P  P+    P+     P
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPT---LPAVIPSSPKEVPATPSSRRDPI----AP 1529

Query: 138  SQQVMTPQGRGTVAAA-AVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMR 196
            +  +++ +   T+A   A+   A    +P + P     P P    ATP     + PP + 
Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSPKKTP---AIPTPKEAPATPSSKEASSPPAVT 1586

Query: 197  P------PMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
            P      P    + +PPA    +  P P   P PP +  PP P   P  P
Sbjct: 1587 PSTYKGAPSPKELLIPPA----VTSPSPKEAPTPPAVT-PPSPEKGPATP 1631



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 45/168 (26%), Positives = 61/168 (36%), Gaps = 28/168 (16%)

Query: 85  PPPKDTGIARVPLAGA-AGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMT 143
           PPP      + PL+ A    P    +     P  VP PQ+ +G A P+     P      
Sbjct: 46  PPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLG--TAPEAPTFL 103

Query: 144 PQGRGTVAAAAVAATASIAGAPTQYPPGRGTP------------PPPVGRATP-PPGIMA 190
           P   G   + A  A AS   APT     +GTP            P  V +++  PP ++ 
Sbjct: 104 PNLIGPPISPAALALASPMIAPTL----KGTPSSSAPLALVALAPHSVQKSSAFPPNLLT 159

Query: 191 PPP-------GMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPP 231
            PP       G    +  PI  P    T +   P  + P P G   PP
Sbjct: 160 SPPSVAVAESGSVITLSAPIA-PSEPKTNLNKVPSEVVPNPKGTPSPP 206



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 33/128 (25%), Positives = 40/128 (31%), Gaps = 6/128 (4%)

Query: 119  PIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPP 178
            P   AP G        G P+   +TP       A    AT+S        P   G P  P
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506

Query: 179  VGRATPPPGIMAPPPGMRPPMGPPIGL-----PPARGTPIGMPPPGMR-PPPPGIRGPPP 232
                + P  + A P   R P+ P   L     P        + PP M  P P      P 
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566

Query: 233  PGMRPPRP 240
            P   P  P
Sbjct: 1567 PKEAPATP 1574



 Score = 28.5 bits (62), Expect = 5.4
 Identities = 33/136 (24%), Positives = 46/136 (33%), Gaps = 23/136 (16%)

Query: 115 PAGVPI------PQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQY 168
           P GV +      P    G AGP   +G  S  V +P     +   +++   S     T +
Sbjct: 796 PLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPV-SPVEASFLPENSLSFQGSKDSPATTH 854

Query: 169 PPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTP----IGMPPPGMRPPP 224
            P            TPP    AP P    P+ P     P + TP    + +P P   P  
Sbjct: 855 SP------------TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902

Query: 225 PGIRGPPPPGMRPPRP 240
           P  +  P   M    P
Sbjct: 903 PAPKQAPALSMTSSSP 918



 Score = 28.1 bits (61), Expect = 7.1
 Identities = 36/157 (22%), Positives = 48/157 (30%), Gaps = 25/157 (15%)

Query: 75   ENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGV 134
            E L+   +  P PK T     P    A             P+       PA      +G 
Sbjct: 1546 EALIPPAMTVPSPKKTPAIPTPKEAPA------------TPSSKEASSPPAVTPSTYKGA 1593

Query: 135  GGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATP-PPGIMAPPP 193
              P + ++ P             + S   APT  PP    P P  G ATP P G    PP
Sbjct: 1594 PSPKELLIPP----------AVTSPSPKEAPT--PPAVTPPSPEKGPATPAPKGTPTSPP 1641

Query: 194  GMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGP 230
                 +      P +    +G   P      P  +GP
Sbjct: 1642 VTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
           sapiens]
          Length = 1424

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 60/177 (33%), Positives = 71/177 (40%), Gaps = 20/177 (11%)

Query: 72  LRGENLVSMTVEGPP--PKDTGIARVP----LAGAAGGPGVGRAAGRGVPAGVPIPQAPA 125
           L+GE   ++  EG    P D G+   P    L G  G PGV    G   P G        
Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG---PKGELALSGEK 592

Query: 126 GLAGPVRGVGGPSQQVMT----PQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGR 181
           G  GP    G P          P G G      +  T  + GAP   PPG   P   +  
Sbjct: 593 GDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG--PPGEAGPRGELSV 650

Query: 182 ATPPPGIMAPP--PGMRPPMGPPIGLPPARGT--PIGMPPPGMRPPPPGIRGPPPPG 234
           +TP PG   PP  PG   P GPP G+P + G     G+P P   P  PGI  P PPG
Sbjct: 651 STPVPGPPGPPGPPGHPGPQGPP-GIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPG 706



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 61/183 (33%), Positives = 69/183 (37%), Gaps = 34/183 (18%)

Query: 86   PPKDTGIARVPLAGAAGGPGV---GRAAGRGVPAGVPIPQAPAGLAGP----VRGVGGPS 138
            P   TGI   P  G  G PG    G+   RG P     P AP G  GP    V G+ G  
Sbjct: 1214 PRGPTGIEGFP--GPPGLPGAIIPGQTGNRGPPGSRGSPGAP-GPPGPPGSHVIGIKGDK 1270

Query: 139  QQVMTPQGRGTVAAAAVAATASIAGAP-TQYPPG-RGTPP----PPVGRATPPPGIMAP- 191
              +  P  +G    A         GAP T   PG RG P     P V      PG +   
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 192  -PPGMRPPMGPP-----------IGLPPARGTPIGMPPPGMR-----PPPPGIRGPPPPG 234
             PPG   P GPP           I LP + G P     PGM+     P PPG  GP  P 
Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390

Query: 235  MRP 237
             +P
Sbjct: 1391 GKP 1393



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/196 (29%), Positives = 68/196 (34%), Gaps = 63/196 (32%)

Query: 97   LAGAAGGPGVGRAAGRGVPA--------GVPIPQAPAGLAGP-----------VRGVGGP 137
            L G AG PG      RGVP         G+P P  P G  G            +RG+ G 
Sbjct: 959  LKGFAGNPG--EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 138  SQQVMTPQGRGTVAAAAVAATASIAGAP-------TQYPPG--RGTPPPPVGRATPP--P 186
               +  P  +G          A   G P        +  PG   GT P P G    P  P
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 187  GIMAP--------PPGMRPPMGPPIGLPPARGTPIGMP-------------------PPG 219
            G M          PPG   P GP  G P + G+P G+P                   PPG
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPE-GAPGSPGSP-GLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 220  MRPPP--PGIRGPPPP 233
            +R PP  PG  G P P
Sbjct: 1135 IRGPPGLPGFPGSPGP 1150



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 56/183 (30%), Positives = 66/183 (36%), Gaps = 23/183 (12%)

Query: 72   LRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG---VGRAAGRGVPAGVPIPQAPAGLA 128
            L G  +   T    PP   G    P  G  G PG   +G    +G   G P P+ P G A
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAP--GPPGPPGSHVIGIKGDKG-SMGHPGPKGPPGTA 1285

Query: 129  ---GPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPP 185
               GP   +G P    + P  RG              G P     G   PP P+G    P
Sbjct: 1286 GDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGVKGEKGNPGFL--GSIGPPGPIG-PKGP 1341

Query: 186  PGIMAPP--------PGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRP 237
            PG+   P        PG   P G P G P  +G P G P P     P G RG P    +P
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTP-GEPGMQGEP-GPPGPPGNLGPCGPRGKPGKDGKP 1399

Query: 238  PRP 240
              P
Sbjct: 1400 GTP 1402



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 54/194 (27%), Positives = 71/194 (36%), Gaps = 43/194 (22%)

Query: 82  VEGPPPKDTGIARVP-LAGAAGGPGVGRAAG-RGVPA-----GVP-IPQAPAGLAGPVRG 133
           + GPP    G+  +P L G  G PG   AAG +G P      G+P  P  P     P  G
Sbjct: 482 IPGPP----GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP--G 535

Query: 134 VGGPSQQVMTPQGR-------------GTVAAAAVAATASIAGAPTQYPPG--------- 171
           + G   + + P+G+             G      +  T  + G P   P G         
Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG--PKGELALSGEKG 593

Query: 172 -RGTPPPPVGRATPPPGIMAPPPGMRPPMGPPI----GLPPARGTPIGMPPPGMRPPPPG 226
            +G P  P    +P P   A PPG  P   P +    G+P A G P    P G       
Sbjct: 594 DQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTP 653

Query: 227 IRGPPPPGMRPPRP 240
           + GPP P   P  P
Sbjct: 654 VPGPPGPPGPPGHP 667



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 54/174 (31%), Positives = 61/174 (35%), Gaps = 38/174 (21%)

Query: 86  PPKDTGIARVP-LAGAAGGPGVGRAAGRGVPA--GVPIPQAPAGLAGPVRG-------VG 135
           PP D G    P  AG AG PG G     G+    GVP    P G AGP RG       V 
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGP-RGELSVSTPVP 655

Query: 136 GPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPP--- 192
           GP      P   G      +  +    G P       G P P      P  G   PP   
Sbjct: 656 GPPGPPGPPGHPGPQGPPGIPGSLGKCGDP-------GLPGPDGEPGIPGIGFPGPPGPK 708

Query: 193 -----PGMRPPMGPP-----------IGLPPARGTP-IGMPPPGMRPPPPGIRG 229
                PG +  +G P            GLP A+G P + MP     P  PG RG
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERG 762



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 44/149 (29%), Positives = 52/149 (34%), Gaps = 22/149 (14%)

Query: 99   GAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGP-----VRGVGGPSQQVMTPQGRGTVAAA 153
            G  G PG+    G   PAG P P+   G  G      +RG+ G    +  P  +G     
Sbjct: 973  GVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032

Query: 154  AVAATASIAGAPTQY--PPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGT 211
                 A   G P  +     +G P    G    PPG          P G P GLP   G 
Sbjct: 1033 GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG----------PTGDP-GLPGDMGK 1081

Query: 212  PIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
               M  PG    PPG  GP  P   P  P
Sbjct: 1082 KGEMGQPG----PPGHLGPAGPEGAPGSP 1106



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 54/165 (32%), Positives = 66/165 (40%), Gaps = 43/165 (26%)

Query: 89   DTGIARVPLAGAAGGPGVGRAAG-RGVPA--GVPIPQAPAGLAGPVRGVGGPSQQVMTPQ 145
            +TG+ R P  G  G PG   A G RG P   G+P  +   G AGP RG  G         
Sbjct: 1171 ETGLLRAP-PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP-RGPTG--------- 1219

Query: 146  GRGTVAAAAVAATASIAGAPTQYPPGR-GTPPPPVGRATP-PPGIMAPPPGMRPPMGPPI 203
                     +       G P    PG+ G   PP  R +P  PG    PPG  PP    I
Sbjct: 1220 ---------IEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG----PPG--PPGSHVI 1264

Query: 204  GLPPARGTPIGMPPPGMRPPP--PGIRGPP-------PPGMRPPR 239
            G+   +G+   M  PG + PP   G  GPP        PG+  PR
Sbjct: 1265 GIKGDKGS---MGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPR 1306



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 30/171 (17%)

Query: 84   GPPPKDTGIARVPLAGAAGGPG----VGRAAGRGVPAGVPIPQAPAGLAGPV-----RGV 134
            GPP +D  I  +   GA G PG     G    RG P G+P  +   G  G       +G 
Sbjct: 883  GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSP-GIPGVKGQRGTPGAKGEQGDKGN 941

Query: 135  GGPSQ--QVMTPQG----RGTVAAAAVAATASIAGAP----TQYPPGRGTPPPPVG--RA 182
             GPS+   V+  +G    +G            + G P     +  PG   PP P G   +
Sbjct: 942  PGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 183  TPPPGIMAPPPGMR--PPMGPPIGLPPARGT--PIGMPPPGMRPPPPGIRG 229
            T  PG     PG+R  P     +G+P ++G    +G P    RP  PGI G
Sbjct: 1002 TGNPG----EPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 51/207 (24%), Positives = 67/207 (32%), Gaps = 57/207 (27%)

Query: 86  PPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPV-------------- 131
           P  + G+         G PG+    G     G+P  Q  AGL G                
Sbjct: 468 PKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGF 527

Query: 132 ------RGVGGPSQQVMTPQGR-------------GTVAAAAVAATASIAGAPTQYPPG- 171
                  G+ G   + + P+G+             G      +  T  + G P   P G 
Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG--PKGE 585

Query: 172 ---------RGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPG--- 219
                    +G P  P    +P P   A PPG  P   P  GL   +G P    PPG   
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP--GLQGTQGVPGAPGPPGEAG 643

Query: 220 ------MRPPPPGIRGPP-PPGMRPPR 239
                 +  P PG  GPP PPG   P+
Sbjct: 644 PRGELSVSTPVPGPPGPPGPPGHPGPQ 670



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 49/157 (31%), Positives = 57/157 (36%), Gaps = 26/157 (16%)

Query: 99  GAAGGPGV-GRAAGRGVPA-----GVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAA 152
           GA G PG+ G+    GVP      GV   +   GL G   G+ G    +  P  RG    
Sbjct: 288 GAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE-DGIKGQKGDIGPPGFRGPTEY 346

Query: 153 AAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLP------ 206
                     G P   PPG      P G  + PPG+   P   RP +    G P      
Sbjct: 347 YDTYQEKGDEGTPG--PPGPRGARGPQG-PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK 403

Query: 207 --------PARGTPIGMPPPGMRPPPPGIRGPP-PPG 234
                    A GTP G P     P  PG  GPP PPG
Sbjct: 404 GERGRPGKDAMGTP-GSPGCAGSPGLPGSPGPPGPPG 439



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 51/181 (28%), Positives = 63/181 (34%), Gaps = 32/181 (17%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVM 142
            +G P    G    P  G  G PG+    G+    G P P    G AGP    G P    +
Sbjct: 1053 KGEPGYSEGTRPGP-PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGL 1111

Query: 143  T----PQG-------RGTVAAAAVAATASIAGAPTQYPP-------GRGTPPPPVGRATP 184
                 P G       +G +    +     + G P    P       GR   P P G    
Sbjct: 1112 PGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE-KG 1170

Query: 185  PPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPP-PGMRPP--------PPGIRG-PPPPG 234
              G++  PPG R   G   G    RG P G P  PG +          P GI G P PPG
Sbjct: 1171 ETGLLRAPPGPRGNPGAQ-GAKGDRGAP-GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 235  M 235
            +
Sbjct: 1229 L 1229



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 47/162 (29%), Positives = 57/162 (35%), Gaps = 21/162 (12%)

Query: 95  VPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPV-RGVGGPSQQVMTPQGRGTVAAA 153
           + L G  G PG     G   P G P    P G  GP  R + GP      P   G     
Sbjct: 770 IGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 154 AVAATASIAGAP-------TQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP---- 202
                    G P       + +P   G+P  P  +    P      PG    +GPP    
Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 203 ----IGLPPARGTPIGMPPPGMRPPPPGIRGPPP-PGMRPPR 239
               +G P A G P    PPG  P  PG RG P  PG++  R
Sbjct: 890 VIGMMGFPGAIGPP---GPPG-NPGTPGQRGSPGIPGVKGQR 927



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 31/175 (17%)

Query: 87   PKDTGIARVPLAGAAGGPGV-------GRAAGRGVPA-----GVPIPQAPAGLAGPVRGV 134
            P   G+ R    G  G PG+       G    RG P      G P      G+ G    +
Sbjct: 841  PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900

Query: 135  G--GPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPP----VGRATPPPGI 188
            G  GP     TP  RG+     V       GA  +    +G P P     V      PG+
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD-KGNPGPSEISHVIGDKGEPGL 959

Query: 189  --MAPPPGMRPPMGPP--IGLPPARGTPIGMPPPGMR--------PPPPGIRGPP 231
               A  PG +   G P   GL   +G P    PPG R        P  PG+RG P
Sbjct: 960  KGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIP 1014



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 49/167 (29%), Positives = 60/167 (35%), Gaps = 32/167 (19%)

Query: 99  GAAGGPGVGRAAGRGVPAGVPIPQAPAGLAG--------PVRGVGGPSQQVMTPQGRGTV 150
           G  G PG     G   P G+P PQ P G  G         VRG+ G      +P   GT 
Sbjct: 52  GFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTP 111

Query: 151 AAAAVAATASIAG-APTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPI------ 203
                     + G + ++   G    P  +G     PGI     G++   G P       
Sbjct: 112 GNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGY----PGIPG-AAGLKGQKGAPAKEEDIE 166

Query: 204 -------GLPPARGTPIGMPPPGMRPPPPGIRGPPP----PGMRPPR 239
                  GLP A G P G+P P   P P G  GPP     PG   PR
Sbjct: 167 LDAKGDPGLPGAPG-PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 50/174 (28%), Positives = 59/174 (33%), Gaps = 35/174 (20%)

Query: 97  LAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVA 156
           L GA G P V    G G P G P  +  +G  G + G+ G      TP   G        
Sbjct: 737 LPGAKGEPAVAMPGGPGTP-GFPGERGNSGEHGEI-GLPGLPGLPGTPGNEGLDGPRGDP 794

Query: 157 ATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP----------IGLP 206
                 G   Q PPGR    P   +  P    +    G R   GP            G P
Sbjct: 795 GQPGPPG--EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFP 852

Query: 207 PARGTPIGMP-------PPGMR--PPPPGIRGPP-----------PPGMRPPRP 240
              G+P G+P       P G R  P  PGI GPP           P  + PP P
Sbjct: 853 GETGSP-GIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP 905



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 46/168 (27%), Positives = 57/168 (33%), Gaps = 38/168 (22%)

Query: 97  LAGAAGGPGVGRAAG----RGVPA----------------GVPIPQ---APAGLAGPVRG 133
           L G  G PG+  AAG    +G PA                G P PQ    P G  GPV  
Sbjct: 137 LPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196

Query: 134 VGGPS----QQVMTPQG-RGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGI 188
            G P        M P+G +G +    +             PPG   PP  V      P  
Sbjct: 197 PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG---PPGTVIVTLTGPDN 253

Query: 189 MAPPPGMRPPMGPPIGLPPARGTPIGMPPPGM-----RPPPPGIRGPP 231
                G +   G  +G P   G P G+P          P  PG++G P
Sbjct: 254 RTDLKGEKGDKG-AMGEPGPPG-PSGLPGESYGSEKGAPGDPGLQGKP 299



 Score = 27.7 bits (60), Expect = 9.2
 Identities = 46/188 (24%), Positives = 62/188 (32%), Gaps = 36/188 (19%)

Query: 86  PPKDTGIARVPLAGAAGGPG-------VGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPS 138
           PP   G    P A    GP        +G    RGV  G+  P  P G    +  + GP 
Sbjct: 196 PPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK-GLTGPPGPPGTV--IVTLTGPD 252

Query: 139 QQVMTPQGRGTVAAAAVAATASIAGAPTQ-YPPGRGTPPPPVGRATP-PPGIMAPP--PG 194
            +      +G   A         +G P + Y   +G P  P  +  P   G+   P   G
Sbjct: 253 NRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG 312

Query: 195 MRPPMGPP--IGLPPARGTPIGMPPPGMRPP--------------------PPGIRGPPP 232
           ++   G P  +G    +G    + PPG R P                    P G RGP  
Sbjct: 313 VKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQG 372

Query: 233 PGMRPPRP 240
           P   P  P
Sbjct: 373 PSGPPGVP 380


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
           sapiens]
          Length = 1494

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 60/177 (33%), Positives = 71/177 (40%), Gaps = 20/177 (11%)

Query: 72  LRGENLVSMTVEGPP--PKDTGIARVP----LAGAAGGPGVGRAAGRGVPAGVPIPQAPA 125
           L+GE   ++  EG    P D G+   P    L G  G PGV    G   P G        
Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG---PKGELALSGEK 592

Query: 126 GLAGPVRGVGGPSQQVMT----PQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGR 181
           G  GP    G P          P G G      +  T  + GAP   PPG   P   +  
Sbjct: 593 GDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG--PPGEAGPRGELSV 650

Query: 182 ATPPPGIMAPP--PGMRPPMGPPIGLPPARGT--PIGMPPPGMRPPPPGIRGPPPPG 234
           +TP PG   PP  PG   P GPP G+P + G     G+P P   P  PGI  P PPG
Sbjct: 651 STPVPGPPGPPGPPGHPGPQGPP-GIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPG 706



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 61/183 (33%), Positives = 69/183 (37%), Gaps = 34/183 (18%)

Query: 86   PPKDTGIARVPLAGAAGGPGV---GRAAGRGVPAGVPIPQAPAGLAGP----VRGVGGPS 138
            P   TGI   P  G  G PG    G+   RG P     P AP G  GP    V G+ G  
Sbjct: 1214 PRGPTGIEGFP--GPPGLPGAIIPGQTGNRGPPGSRGSPGAP-GPPGPPGSHVIGIKGDK 1270

Query: 139  QQVMTPQGRGTVAAAAVAATASIAGAP-TQYPPG-RGTPP----PPVGRATPPPGIMAP- 191
              +  P  +G    A         GAP T   PG RG P     P V      PG +   
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 192  -PPGMRPPMGPP-----------IGLPPARGTPIGMPPPGMR-----PPPPGIRGPPPPG 234
             PPG   P GPP           I LP + G P     PGM+     P PPG  GP  P 
Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390

Query: 235  MRP 237
             +P
Sbjct: 1391 GKP 1393



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/196 (29%), Positives = 68/196 (34%), Gaps = 63/196 (32%)

Query: 97   LAGAAGGPGVGRAAGRGVPA--------GVPIPQAPAGLAGP-----------VRGVGGP 137
            L G AG PG      RGVP         G+P P  P G  G            +RG+ G 
Sbjct: 959  LKGFAGNPG--EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 138  SQQVMTPQGRGTVAAAAVAATASIAGAP-------TQYPPG--RGTPPPPVGRATPP--P 186
               +  P  +G          A   G P        +  PG   GT P P G    P  P
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 187  GIMAP--------PPGMRPPMGPPIGLPPARGTPIGMP-------------------PPG 219
            G M          PPG   P GP  G P + G+P G+P                   PPG
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPE-GAPGSPGSP-GLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 220  MRPPP--PGIRGPPPP 233
            +R PP  PG  G P P
Sbjct: 1135 IRGPPGLPGFPGSPGP 1150



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 56/183 (30%), Positives = 66/183 (36%), Gaps = 23/183 (12%)

Query: 72   LRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG---VGRAAGRGVPAGVPIPQAPAGLA 128
            L G  +   T    PP   G    P  G  G PG   +G    +G   G P P+ P G A
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAP--GPPGPPGSHVIGIKGDKG-SMGHPGPKGPPGTA 1285

Query: 129  ---GPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPP 185
               GP   +G P    + P  RG              G P     G   PP P+G    P
Sbjct: 1286 GDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGVKGEKGNPGFL--GSIGPPGPIG-PKGP 1341

Query: 186  PGIMAPP--------PGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRP 237
            PG+   P        PG   P G P G P  +G P G P P     P G RG P    +P
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTP-GEPGMQGEP-GPPGPPGNLGPCGPRGKPGKDGKP 1399

Query: 238  PRP 240
              P
Sbjct: 1400 GTP 1402



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 54/194 (27%), Positives = 71/194 (36%), Gaps = 43/194 (22%)

Query: 82  VEGPPPKDTGIARVP-LAGAAGGPGVGRAAG-RGVPA-----GVP-IPQAPAGLAGPVRG 133
           + GPP    G+  +P L G  G PG   AAG +G P      G+P  P  P     P  G
Sbjct: 482 IPGPP----GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP--G 535

Query: 134 VGGPSQQVMTPQGR-------------GTVAAAAVAATASIAGAPTQYPPG--------- 171
           + G   + + P+G+             G      +  T  + G P   P G         
Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG--PKGELALSGEKG 593

Query: 172 -RGTPPPPVGRATPPPGIMAPPPGMRPPMGPPI----GLPPARGTPIGMPPPGMRPPPPG 226
            +G P  P    +P P   A PPG  P   P +    G+P A G P    P G       
Sbjct: 594 DQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTP 653

Query: 227 IRGPPPPGMRPPRP 240
           + GPP P   P  P
Sbjct: 654 VPGPPGPPGPPGHP 667



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 54/174 (31%), Positives = 61/174 (35%), Gaps = 38/174 (21%)

Query: 86  PPKDTGIARVP-LAGAAGGPGVGRAAGRGVPA--GVPIPQAPAGLAGPVRG-------VG 135
           PP D G    P  AG AG PG G     G+    GVP    P G AGP RG       V 
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGP-RGELSVSTPVP 655

Query: 136 GPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPP--- 192
           GP      P   G      +  +    G P       G P P      P  G   PP   
Sbjct: 656 GPPGPPGPPGHPGPQGPPGIPGSLGKCGDP-------GLPGPDGEPGIPGIGFPGPPGPK 708

Query: 193 -----PGMRPPMGPP-----------IGLPPARGTP-IGMPPPGMRPPPPGIRG 229
                PG +  +G P            GLP A+G P + MP     P  PG RG
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERG 762



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 44/149 (29%), Positives = 52/149 (34%), Gaps = 22/149 (14%)

Query: 99   GAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGP-----VRGVGGPSQQVMTPQGRGTVAAA 153
            G  G PG+    G   PAG P P+   G  G      +RG+ G    +  P  +G     
Sbjct: 973  GVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032

Query: 154  AVAATASIAGAPTQY--PPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGT 211
                 A   G P  +     +G P    G    PPG          P G P GLP   G 
Sbjct: 1033 GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG----------PTGDP-GLPGDMGK 1081

Query: 212  PIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
               M  PG    PPG  GP  P   P  P
Sbjct: 1082 KGEMGQPG----PPGHLGPAGPEGAPGSP 1106



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 54/165 (32%), Positives = 66/165 (40%), Gaps = 43/165 (26%)

Query: 89   DTGIARVPLAGAAGGPGVGRAAG-RGVPA--GVPIPQAPAGLAGPVRGVGGPSQQVMTPQ 145
            +TG+ R P  G  G PG   A G RG P   G+P  +   G AGP RG  G         
Sbjct: 1171 ETGLLRAP-PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP-RGPTG--------- 1219

Query: 146  GRGTVAAAAVAATASIAGAPTQYPPGR-GTPPPPVGRATP-PPGIMAPPPGMRPPMGPPI 203
                     +       G P    PG+ G   PP  R +P  PG    PPG  PP    I
Sbjct: 1220 ---------IEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG----PPG--PPGSHVI 1264

Query: 204  GLPPARGTPIGMPPPGMRPPP--PGIRGPP-------PPGMRPPR 239
            G+   +G+   M  PG + PP   G  GPP        PG+  PR
Sbjct: 1265 GIKGDKGS---MGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPR 1306



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 30/171 (17%)

Query: 84   GPPPKDTGIARVPLAGAAGGPG----VGRAAGRGVPAGVPIPQAPAGLAGPV-----RGV 134
            GPP +D  I  +   GA G PG     G    RG P G+P  +   G  G       +G 
Sbjct: 883  GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSP-GIPGVKGQRGTPGAKGEQGDKGN 941

Query: 135  GGPSQ--QVMTPQG----RGTVAAAAVAATASIAGAP----TQYPPGRGTPPPPVG--RA 182
             GPS+   V+  +G    +G            + G P     +  PG   PP P G   +
Sbjct: 942  PGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 183  TPPPGIMAPPPGMR--PPMGPPIGLPPARGT--PIGMPPPGMRPPPPGIRG 229
            T  PG     PG+R  P     +G+P ++G    +G P    RP  PGI G
Sbjct: 1002 TGNPG----EPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 51/207 (24%), Positives = 67/207 (32%), Gaps = 57/207 (27%)

Query: 86  PPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPV-------------- 131
           P  + G+         G PG+    G     G+P  Q  AGL G                
Sbjct: 468 PKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGF 527

Query: 132 ------RGVGGPSQQVMTPQGR-------------GTVAAAAVAATASIAGAPTQYPPG- 171
                  G+ G   + + P+G+             G      +  T  + G P   P G 
Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG--PKGE 585

Query: 172 ---------RGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPG--- 219
                    +G P  P    +P P   A PPG  P   P  GL   +G P    PPG   
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP--GLQGTQGVPGAPGPPGEAG 643

Query: 220 ------MRPPPPGIRGPP-PPGMRPPR 239
                 +  P PG  GPP PPG   P+
Sbjct: 644 PRGELSVSTPVPGPPGPPGPPGHPGPQ 670



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 49/157 (31%), Positives = 57/157 (36%), Gaps = 26/157 (16%)

Query: 99  GAAGGPGV-GRAAGRGVPA-----GVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAA 152
           GA G PG+ G+    GVP      GV   +   GL G   G+ G    +  P  RG    
Sbjct: 288 GAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE-DGIKGQKGDIGPPGFRGPTEY 346

Query: 153 AAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLP------ 206
                     G P   PPG      P G  + PPG+   P   RP +    G P      
Sbjct: 347 YDTYQEKGDEGTPG--PPGPRGARGPQG-PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK 403

Query: 207 --------PARGTPIGMPPPGMRPPPPGIRGPP-PPG 234
                    A GTP G P     P  PG  GPP PPG
Sbjct: 404 GERGRPGKDAMGTP-GSPGCAGSPGLPGSPGPPGPPG 439



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 51/181 (28%), Positives = 63/181 (34%), Gaps = 32/181 (17%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVM 142
            +G P    G    P  G  G PG+    G+    G P P    G AGP    G P    +
Sbjct: 1053 KGEPGYSEGTRPGP-PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGL 1111

Query: 143  T----PQG-------RGTVAAAAVAATASIAGAPTQYPP-------GRGTPPPPVGRATP 184
                 P G       +G +    +     + G P    P       GR   P P G    
Sbjct: 1112 PGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE-KG 1170

Query: 185  PPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPP-PGMRPP--------PPGIRG-PPPPG 234
              G++  PPG R   G   G    RG P G P  PG +          P GI G P PPG
Sbjct: 1171 ETGLLRAPPGPRGNPGAQ-GAKGDRGAP-GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 235  M 235
            +
Sbjct: 1229 L 1229



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 47/162 (29%), Positives = 57/162 (35%), Gaps = 21/162 (12%)

Query: 95  VPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPV-RGVGGPSQQVMTPQGRGTVAAA 153
           + L G  G PG     G   P G P    P G  GP  R + GP      P   G     
Sbjct: 770 IGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 154 AVAATASIAGAP-------TQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP---- 202
                    G P       + +P   G+P  P  +    P      PG    +GPP    
Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 203 ----IGLPPARGTPIGMPPPGMRPPPPGIRGPPP-PGMRPPR 239
               +G P A G P    PPG  P  PG RG P  PG++  R
Sbjct: 890 VIGMMGFPGAIGPP---GPPG-NPGTPGQRGSPGIPGVKGQR 927



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 31/175 (17%)

Query: 87   PKDTGIARVPLAGAAGGPGV-------GRAAGRGVPA-----GVPIPQAPAGLAGPVRGV 134
            P   G+ R    G  G PG+       G    RG P      G P      G+ G    +
Sbjct: 841  PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900

Query: 135  G--GPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPP----VGRATPPPGI 188
            G  GP     TP  RG+     V       GA  +    +G P P     V      PG+
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD-KGNPGPSEISHVIGDKGEPGL 959

Query: 189  --MAPPPGMRPPMGPP--IGLPPARGTPIGMPPPGMR--------PPPPGIRGPP 231
               A  PG +   G P   GL   +G P    PPG R        P  PG+RG P
Sbjct: 960  KGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIP 1014



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 49/167 (29%), Positives = 60/167 (35%), Gaps = 32/167 (19%)

Query: 99  GAAGGPGVGRAAGRGVPAGVPIPQAPAGLAG--------PVRGVGGPSQQVMTPQGRGTV 150
           G  G PG     G   P G+P PQ P G  G         VRG+ G      +P   GT 
Sbjct: 52  GFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTP 111

Query: 151 AAAAVAATASIAG-APTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPI------ 203
                     + G + ++   G    P  +G     PGI     G++   G P       
Sbjct: 112 GNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGY----PGIPG-AAGLKGQKGAPAKEEDIE 166

Query: 204 -------GLPPARGTPIGMPPPGMRPPPPGIRGPPP----PGMRPPR 239
                  GLP A G P G+P P   P P G  GPP     PG   PR
Sbjct: 167 LDAKGDPGLPGAPG-PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 50/174 (28%), Positives = 59/174 (33%), Gaps = 35/174 (20%)

Query: 97  LAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVA 156
           L GA G P V    G G P G P  +  +G  G + G+ G      TP   G        
Sbjct: 737 LPGAKGEPAVAMPGGPGTP-GFPGERGNSGEHGEI-GLPGLPGLPGTPGNEGLDGPRGDP 794

Query: 157 ATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP----------IGLP 206
                 G   Q PPGR    P   +  P    +    G R   GP            G P
Sbjct: 795 GQPGPPG--EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFP 852

Query: 207 PARGTPIGMP-------PPGMR--PPPPGIRGPP-----------PPGMRPPRP 240
              G+P G+P       P G R  P  PGI GPP           P  + PP P
Sbjct: 853 GETGSP-GIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP 905



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 46/168 (27%), Positives = 57/168 (33%), Gaps = 38/168 (22%)

Query: 97  LAGAAGGPGVGRAAG----RGVPA----------------GVPIPQ---APAGLAGPVRG 133
           L G  G PG+  AAG    +G PA                G P PQ    P G  GPV  
Sbjct: 137 LPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196

Query: 134 VGGPS----QQVMTPQG-RGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGI 188
            G P        M P+G +G +    +             PPG   PP  V      P  
Sbjct: 197 PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG---PPGTVIVTLTGPDN 253

Query: 189 MAPPPGMRPPMGPPIGLPPARGTPIGMPPPGM-----RPPPPGIRGPP 231
                G +   G  +G P   G P G+P          P  PG++G P
Sbjct: 254 RTDLKGEKGDKG-AMGEPGPPG-PSGLPGESYGSEKGAPGDPGLQGKP 299



 Score = 27.7 bits (60), Expect = 9.2
 Identities = 46/188 (24%), Positives = 62/188 (32%), Gaps = 36/188 (19%)

Query: 86  PPKDTGIARVPLAGAAGGPG-------VGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPS 138
           PP   G    P A    GP        +G    RGV  G+  P  P G    +  + GP 
Sbjct: 196 PPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK-GLTGPPGPPGTV--IVTLTGPD 252

Query: 139 QQVMTPQGRGTVAAAAVAATASIAGAPTQ-YPPGRGTPPPPVGRATP-PPGIMAPP--PG 194
            +      +G   A         +G P + Y   +G P  P  +  P   G+   P   G
Sbjct: 253 NRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG 312

Query: 195 MRPPMGPP--IGLPPARGTPIGMPPPGMRPP--------------------PPGIRGPPP 232
           ++   G P  +G    +G    + PPG R P                    P G RGP  
Sbjct: 313 VKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQG 372

Query: 233 PGMRPPRP 240
           P   P  P
Sbjct: 373 PSGPPGVP 380


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1637

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 60/177 (33%), Positives = 71/177 (40%), Gaps = 20/177 (11%)

Query: 72  LRGENLVSMTVEGPP--PKDTGIARVP----LAGAAGGPGVGRAAGRGVPAGVPIPQAPA 125
           L+GE   ++  EG    P D G+   P    L G  G PGV    G   P G        
Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG---PKGELALSGEK 592

Query: 126 GLAGPVRGVGGPSQQVMT----PQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGR 181
           G  GP    G P          P G G      +  T  + GAP   PPG   P   +  
Sbjct: 593 GDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG--PPGEAGPRGELSV 650

Query: 182 ATPPPGIMAPP--PGMRPPMGPPIGLPPARGT--PIGMPPPGMRPPPPGIRGPPPPG 234
           +TP PG   PP  PG   P GPP G+P + G     G+P P   P  PGI  P PPG
Sbjct: 651 STPVPGPPGPPGPPGHPGPQGPP-GIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPG 706



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 61/183 (33%), Positives = 69/183 (37%), Gaps = 34/183 (18%)

Query: 86   PPKDTGIARVPLAGAAGGPGV---GRAAGRGVPAGVPIPQAPAGLAGP----VRGVGGPS 138
            P   TGI   P  G  G PG    G+   RG P     P AP G  GP    V G+ G  
Sbjct: 1214 PRGPTGIEGFP--GPPGLPGAIIPGQTGNRGPPGSRGSPGAP-GPPGPPGSHVIGIKGDK 1270

Query: 139  QQVMTPQGRGTVAAAAVAATASIAGAP-TQYPPG-RGTPP----PPVGRATPPPGIMAP- 191
              +  P  +G    A         GAP T   PG RG P     P V      PG +   
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 192  -PPGMRPPMGPP-----------IGLPPARGTPIGMPPPGMR-----PPPPGIRGPPPPG 234
             PPG   P GPP           I LP + G P     PGM+     P PPG  GP  P 
Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390

Query: 235  MRP 237
             +P
Sbjct: 1391 GKP 1393



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/196 (29%), Positives = 68/196 (34%), Gaps = 63/196 (32%)

Query: 97   LAGAAGGPGVGRAAGRGVPA--------GVPIPQAPAGLAGP-----------VRGVGGP 137
            L G AG PG      RGVP         G+P P  P G  G            +RG+ G 
Sbjct: 959  LKGFAGNPG--EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 138  SQQVMTPQGRGTVAAAAVAATASIAGAP-------TQYPPG--RGTPPPPVGRATPP--P 186
               +  P  +G          A   G P        +  PG   GT P P G    P  P
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 187  GIMAP--------PPGMRPPMGPPIGLPPARGTPIGMP-------------------PPG 219
            G M          PPG   P GP  G P + G+P G+P                   PPG
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPE-GAPGSPGSP-GLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 220  MRPPP--PGIRGPPPP 233
            +R PP  PG  G P P
Sbjct: 1135 IRGPPGLPGFPGSPGP 1150



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 56/183 (30%), Positives = 66/183 (36%), Gaps = 23/183 (12%)

Query: 72   LRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG---VGRAAGRGVPAGVPIPQAPAGLA 128
            L G  +   T    PP   G    P  G  G PG   +G    +G   G P P+ P G A
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAP--GPPGPPGSHVIGIKGDKG-SMGHPGPKGPPGTA 1285

Query: 129  ---GPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPP 185
               GP   +G P    + P  RG              G P     G   PP P+G    P
Sbjct: 1286 GDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGVKGEKGNPGFL--GSIGPPGPIG-PKGP 1341

Query: 186  PGIMAPP--------PGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRP 237
            PG+   P        PG   P G P G P  +G P G P P     P G RG P    +P
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTP-GEPGMQGEP-GPPGPPGNLGPCGPRGKPGKDGKP 1399

Query: 238  PRP 240
              P
Sbjct: 1400 GTP 1402



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 54/194 (27%), Positives = 71/194 (36%), Gaps = 43/194 (22%)

Query: 82  VEGPPPKDTGIARVP-LAGAAGGPGVGRAAG-RGVPA-----GVP-IPQAPAGLAGPVRG 133
           + GPP    G+  +P L G  G PG   AAG +G P      G+P  P  P     P  G
Sbjct: 482 IPGPP----GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP--G 535

Query: 134 VGGPSQQVMTPQGR-------------GTVAAAAVAATASIAGAPTQYPPG--------- 171
           + G   + + P+G+             G      +  T  + G P   P G         
Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG--PKGELALSGEKG 593

Query: 172 -RGTPPPPVGRATPPPGIMAPPPGMRPPMGPPI----GLPPARGTPIGMPPPGMRPPPPG 226
            +G P  P    +P P   A PPG  P   P +    G+P A G P    P G       
Sbjct: 594 DQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTP 653

Query: 227 IRGPPPPGMRPPRP 240
           + GPP P   P  P
Sbjct: 654 VPGPPGPPGPPGHP 667



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 54/174 (31%), Positives = 61/174 (35%), Gaps = 38/174 (21%)

Query: 86  PPKDTGIARVP-LAGAAGGPGVGRAAGRGVPA--GVPIPQAPAGLAGPVRG-------VG 135
           PP D G    P  AG AG PG G     G+    GVP    P G AGP RG       V 
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGP-RGELSVSTPVP 655

Query: 136 GPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPP--- 192
           GP      P   G      +  +    G P       G P P      P  G   PP   
Sbjct: 656 GPPGPPGPPGHPGPQGPPGIPGSLGKCGDP-------GLPGPDGEPGIPGIGFPGPPGPK 708

Query: 193 -----PGMRPPMGPP-----------IGLPPARGTP-IGMPPPGMRPPPPGIRG 229
                PG +  +G P            GLP A+G P + MP     P  PG RG
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERG 762



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 44/149 (29%), Positives = 52/149 (34%), Gaps = 22/149 (14%)

Query: 99   GAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGP-----VRGVGGPSQQVMTPQGRGTVAAA 153
            G  G PG+    G   PAG P P+   G  G      +RG+ G    +  P  +G     
Sbjct: 973  GVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032

Query: 154  AVAATASIAGAPTQY--PPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGT 211
                 A   G P  +     +G P    G    PPG          P G P GLP   G 
Sbjct: 1033 GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG----------PTGDP-GLPGDMGK 1081

Query: 212  PIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
               M  PG    PPG  GP  P   P  P
Sbjct: 1082 KGEMGQPG----PPGHLGPAGPEGAPGSP 1106



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 54/165 (32%), Positives = 66/165 (40%), Gaps = 43/165 (26%)

Query: 89   DTGIARVPLAGAAGGPGVGRAAG-RGVPA--GVPIPQAPAGLAGPVRGVGGPSQQVMTPQ 145
            +TG+ R P  G  G PG   A G RG P   G+P  +   G AGP RG  G         
Sbjct: 1171 ETGLLRAP-PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP-RGPTG--------- 1219

Query: 146  GRGTVAAAAVAATASIAGAPTQYPPGR-GTPPPPVGRATP-PPGIMAPPPGMRPPMGPPI 203
                     +       G P    PG+ G   PP  R +P  PG    PPG  PP    I
Sbjct: 1220 ---------IEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG----PPG--PPGSHVI 1264

Query: 204  GLPPARGTPIGMPPPGMRPPP--PGIRGPP-------PPGMRPPR 239
            G+   +G+   M  PG + PP   G  GPP        PG+  PR
Sbjct: 1265 GIKGDKGS---MGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPR 1306



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 30/171 (17%)

Query: 84   GPPPKDTGIARVPLAGAAGGPG----VGRAAGRGVPAGVPIPQAPAGLAGPV-----RGV 134
            GPP +D  I  +   GA G PG     G    RG P G+P  +   G  G       +G 
Sbjct: 883  GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSP-GIPGVKGQRGTPGAKGEQGDKGN 941

Query: 135  GGPSQ--QVMTPQG----RGTVAAAAVAATASIAGAP----TQYPPGRGTPPPPVG--RA 182
             GPS+   V+  +G    +G            + G P     +  PG   PP P G   +
Sbjct: 942  PGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 183  TPPPGIMAPPPGMR--PPMGPPIGLPPARGT--PIGMPPPGMRPPPPGIRG 229
            T  PG     PG+R  P     +G+P ++G    +G P    RP  PGI G
Sbjct: 1002 TGNPG----EPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 51/207 (24%), Positives = 67/207 (32%), Gaps = 57/207 (27%)

Query: 86  PPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPV-------------- 131
           P  + G+         G PG+    G     G+P  Q  AGL G                
Sbjct: 468 PKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGF 527

Query: 132 ------RGVGGPSQQVMTPQGR-------------GTVAAAAVAATASIAGAPTQYPPG- 171
                  G+ G   + + P+G+             G      +  T  + G P   P G 
Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG--PKGE 585

Query: 172 ---------RGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPG--- 219
                    +G P  P    +P P   A PPG  P   P  GL   +G P    PPG   
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP--GLQGTQGVPGAPGPPGEAG 643

Query: 220 ------MRPPPPGIRGPP-PPGMRPPR 239
                 +  P PG  GPP PPG   P+
Sbjct: 644 PRGELSVSTPVPGPPGPPGPPGHPGPQ 670



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 49/157 (31%), Positives = 57/157 (36%), Gaps = 26/157 (16%)

Query: 99  GAAGGPGV-GRAAGRGVPA-----GVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAA 152
           GA G PG+ G+    GVP      GV   +   GL G   G+ G    +  P  RG    
Sbjct: 288 GAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE-DGIKGQKGDIGPPGFRGPTEY 346

Query: 153 AAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLP------ 206
                     G P   PPG      P G  + PPG+   P   RP +    G P      
Sbjct: 347 YDTYQEKGDEGTPG--PPGPRGARGPQG-PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK 403

Query: 207 --------PARGTPIGMPPPGMRPPPPGIRGPP-PPG 234
                    A GTP G P     P  PG  GPP PPG
Sbjct: 404 GERGRPGKDAMGTP-GSPGCAGSPGLPGSPGPPGPPG 439



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 51/181 (28%), Positives = 63/181 (34%), Gaps = 32/181 (17%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVM 142
            +G P    G    P  G  G PG+    G+    G P P    G AGP    G P    +
Sbjct: 1053 KGEPGYSEGTRPGP-PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGL 1111

Query: 143  T----PQG-------RGTVAAAAVAATASIAGAPTQYPP-------GRGTPPPPVGRATP 184
                 P G       +G +    +     + G P    P       GR   P P G    
Sbjct: 1112 PGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE-KG 1170

Query: 185  PPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPP-PGMRPP--------PPGIRG-PPPPG 234
              G++  PPG R   G   G    RG P G P  PG +          P GI G P PPG
Sbjct: 1171 ETGLLRAPPGPRGNPGAQ-GAKGDRGAP-GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 235  M 235
            +
Sbjct: 1229 L 1229



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 47/162 (29%), Positives = 57/162 (35%), Gaps = 21/162 (12%)

Query: 95  VPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPV-RGVGGPSQQVMTPQGRGTVAAA 153
           + L G  G PG     G   P G P    P G  GP  R + GP      P   G     
Sbjct: 770 IGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 154 AVAATASIAGAP-------TQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP---- 202
                    G P       + +P   G+P  P  +    P      PG    +GPP    
Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 203 ----IGLPPARGTPIGMPPPGMRPPPPGIRGPPP-PGMRPPR 239
               +G P A G P    PPG  P  PG RG P  PG++  R
Sbjct: 890 VIGMMGFPGAIGPP---GPPG-NPGTPGQRGSPGIPGVKGQR 927



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 31/175 (17%)

Query: 87   PKDTGIARVPLAGAAGGPGV-------GRAAGRGVPA-----GVPIPQAPAGLAGPVRGV 134
            P   G+ R    G  G PG+       G    RG P      G P      G+ G    +
Sbjct: 841  PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900

Query: 135  G--GPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPP----VGRATPPPGI 188
            G  GP     TP  RG+     V       GA  +    +G P P     V      PG+
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD-KGNPGPSEISHVIGDKGEPGL 959

Query: 189  --MAPPPGMRPPMGPP--IGLPPARGTPIGMPPPGMR--------PPPPGIRGPP 231
               A  PG +   G P   GL   +G P    PPG R        P  PG+RG P
Sbjct: 960  KGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIP 1014



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 49/167 (29%), Positives = 60/167 (35%), Gaps = 32/167 (19%)

Query: 99  GAAGGPGVGRAAGRGVPAGVPIPQAPAGLAG--------PVRGVGGPSQQVMTPQGRGTV 150
           G  G PG     G   P G+P PQ P G  G         VRG+ G      +P   GT 
Sbjct: 52  GFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTP 111

Query: 151 AAAAVAATASIAG-APTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPI------ 203
                     + G + ++   G    P  +G     PGI     G++   G P       
Sbjct: 112 GNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGY----PGIPG-AAGLKGQKGAPAKEEDIE 166

Query: 204 -------GLPPARGTPIGMPPPGMRPPPPGIRGPPP----PGMRPPR 239
                  GLP A G P G+P P   P P G  GPP     PG   PR
Sbjct: 167 LDAKGDPGLPGAPG-PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 50/174 (28%), Positives = 59/174 (33%), Gaps = 35/174 (20%)

Query: 97  LAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVA 156
           L GA G P V    G G P G P  +  +G  G + G+ G      TP   G        
Sbjct: 737 LPGAKGEPAVAMPGGPGTP-GFPGERGNSGEHGEI-GLPGLPGLPGTPGNEGLDGPRGDP 794

Query: 157 ATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP----------IGLP 206
                 G   Q PPGR    P   +  P    +    G R   GP            G P
Sbjct: 795 GQPGPPG--EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFP 852

Query: 207 PARGTPIGMP-------PPGMR--PPPPGIRGPP-----------PPGMRPPRP 240
              G+P G+P       P G R  P  PGI GPP           P  + PP P
Sbjct: 853 GETGSP-GIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP 905



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 46/168 (27%), Positives = 57/168 (33%), Gaps = 38/168 (22%)

Query: 97  LAGAAGGPGVGRAAG----RGVPA----------------GVPIPQ---APAGLAGPVRG 133
           L G  G PG+  AAG    +G PA                G P PQ    P G  GPV  
Sbjct: 137 LPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196

Query: 134 VGGPS----QQVMTPQG-RGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGI 188
            G P        M P+G +G +    +             PPG   PP  V      P  
Sbjct: 197 PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG---PPGTVIVTLTGPDN 253

Query: 189 MAPPPGMRPPMGPPIGLPPARGTPIGMPPPGM-----RPPPPGIRGPP 231
                G +   G  +G P   G P G+P          P  PG++G P
Sbjct: 254 RTDLKGEKGDKG-AMGEPGPPG-PSGLPGESYGSEKGAPGDPGLQGKP 299



 Score = 27.7 bits (60), Expect = 9.2
 Identities = 46/188 (24%), Positives = 62/188 (32%), Gaps = 36/188 (19%)

Query: 86  PPKDTGIARVPLAGAAGGPG-------VGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPS 138
           PP   G    P A    GP        +G    RGV  G+  P  P G    +  + GP 
Sbjct: 196 PPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK-GLTGPPGPPGTV--IVTLTGPD 252

Query: 139 QQVMTPQGRGTVAAAAVAATASIAGAPTQ-YPPGRGTPPPPVGRATP-PPGIMAPP--PG 194
            +      +G   A         +G P + Y   +G P  P  +  P   G+   P   G
Sbjct: 253 NRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG 312

Query: 195 MRPPMGPP--IGLPPARGTPIGMPPPGMRPP--------------------PPGIRGPPP 232
           ++   G P  +G    +G    + PPG R P                    P G RGP  
Sbjct: 313 VKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQG 372

Query: 233 PGMRPPRP 240
           P   P  P
Sbjct: 373 PSGPPGVP 380


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1670

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 60/177 (33%), Positives = 71/177 (40%), Gaps = 20/177 (11%)

Query: 72  LRGENLVSMTVEGPP--PKDTGIARVP----LAGAAGGPGVGRAAGRGVPAGVPIPQAPA 125
           L+GE   ++  EG    P D G+   P    L G  G PGV    G   P G        
Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG---PKGELALSGEK 592

Query: 126 GLAGPVRGVGGPSQQVMT----PQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGR 181
           G  GP    G P          P G G      +  T  + GAP   PPG   P   +  
Sbjct: 593 GDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG--PPGEAGPRGELSV 650

Query: 182 ATPPPGIMAPP--PGMRPPMGPPIGLPPARGT--PIGMPPPGMRPPPPGIRGPPPPG 234
           +TP PG   PP  PG   P GPP G+P + G     G+P P   P  PGI  P PPG
Sbjct: 651 STPVPGPPGPPGPPGHPGPQGPP-GIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPG 706



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 61/183 (33%), Positives = 69/183 (37%), Gaps = 34/183 (18%)

Query: 86   PPKDTGIARVPLAGAAGGPGV---GRAAGRGVPAGVPIPQAPAGLAGP----VRGVGGPS 138
            P   TGI   P  G  G PG    G+   RG P     P AP G  GP    V G+ G  
Sbjct: 1214 PRGPTGIEGFP--GPPGLPGAIIPGQTGNRGPPGSRGSPGAP-GPPGPPGSHVIGIKGDK 1270

Query: 139  QQVMTPQGRGTVAAAAVAATASIAGAP-TQYPPG-RGTPP----PPVGRATPPPGIMAP- 191
              +  P  +G    A         GAP T   PG RG P     P V      PG +   
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 192  -PPGMRPPMGPP-----------IGLPPARGTPIGMPPPGMR-----PPPPGIRGPPPPG 234
             PPG   P GPP           I LP + G P     PGM+     P PPG  GP  P 
Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390

Query: 235  MRP 237
             +P
Sbjct: 1391 GKP 1393



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/196 (29%), Positives = 68/196 (34%), Gaps = 63/196 (32%)

Query: 97   LAGAAGGPGVGRAAGRGVPA--------GVPIPQAPAGLAGP-----------VRGVGGP 137
            L G AG PG      RGVP         G+P P  P G  G            +RG+ G 
Sbjct: 959  LKGFAGNPG--EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 138  SQQVMTPQGRGTVAAAAVAATASIAGAP-------TQYPPG--RGTPPPPVGRATPP--P 186
               +  P  +G          A   G P        +  PG   GT P P G    P  P
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 187  GIMAP--------PPGMRPPMGPPIGLPPARGTPIGMP-------------------PPG 219
            G M          PPG   P GP  G P + G+P G+P                   PPG
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPE-GAPGSPGSP-GLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 220  MRPPP--PGIRGPPPP 233
            +R PP  PG  G P P
Sbjct: 1135 IRGPPGLPGFPGSPGP 1150



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 56/183 (30%), Positives = 66/183 (36%), Gaps = 23/183 (12%)

Query: 72   LRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPG---VGRAAGRGVPAGVPIPQAPAGLA 128
            L G  +   T    PP   G    P  G  G PG   +G    +G   G P P+ P G A
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAP--GPPGPPGSHVIGIKGDKG-SMGHPGPKGPPGTA 1285

Query: 129  ---GPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPP 185
               GP   +G P    + P  RG              G P     G   PP P+G    P
Sbjct: 1286 GDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGVKGEKGNPGFL--GSIGPPGPIG-PKGP 1341

Query: 186  PGIMAPP--------PGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRP 237
            PG+   P        PG   P G P G P  +G P G P P     P G RG P    +P
Sbjct: 1342 PGVRGDPGTLKIISLPGSPGPPGTP-GEPGMQGEP-GPPGPPGNLGPCGPRGKPGKDGKP 1399

Query: 238  PRP 240
              P
Sbjct: 1400 GTP 1402



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 54/194 (27%), Positives = 71/194 (36%), Gaps = 43/194 (22%)

Query: 82  VEGPPPKDTGIARVP-LAGAAGGPGVGRAAG-RGVPA-----GVP-IPQAPAGLAGPVRG 133
           + GPP    G+  +P L G  G PG   AAG +G P      G+P  P  P     P  G
Sbjct: 482 IPGPP----GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP--G 535

Query: 134 VGGPSQQVMTPQGR-------------GTVAAAAVAATASIAGAPTQYPPG--------- 171
           + G   + + P+G+             G      +  T  + G P   P G         
Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG--PKGELALSGEKG 593

Query: 172 -RGTPPPPVGRATPPPGIMAPPPGMRPPMGPPI----GLPPARGTPIGMPPPGMRPPPPG 226
            +G P  P    +P P   A PPG  P   P +    G+P A G P    P G       
Sbjct: 594 DQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTP 653

Query: 227 IRGPPPPGMRPPRP 240
           + GPP P   P  P
Sbjct: 654 VPGPPGPPGPPGHP 667



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 54/174 (31%), Positives = 61/174 (35%), Gaps = 38/174 (21%)

Query: 86  PPKDTGIARVP-LAGAAGGPGVGRAAGRGVPA--GVPIPQAPAGLAGPVRG-------VG 135
           PP D G    P  AG AG PG G     G+    GVP    P G AGP RG       V 
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGP-RGELSVSTPVP 655

Query: 136 GPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPP--- 192
           GP      P   G      +  +    G P       G P P      P  G   PP   
Sbjct: 656 GPPGPPGPPGHPGPQGPPGIPGSLGKCGDP-------GLPGPDGEPGIPGIGFPGPPGPK 708

Query: 193 -----PGMRPPMGPP-----------IGLPPARGTP-IGMPPPGMRPPPPGIRG 229
                PG +  +G P            GLP A+G P + MP     P  PG RG
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERG 762



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 44/149 (29%), Positives = 52/149 (34%), Gaps = 22/149 (14%)

Query: 99   GAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGP-----VRGVGGPSQQVMTPQGRGTVAAA 153
            G  G PG+    G   PAG P P+   G  G      +RG+ G    +  P  +G     
Sbjct: 973  GVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032

Query: 154  AVAATASIAGAPTQY--PPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGT 211
                 A   G P  +     +G P    G    PPG          P G P GLP   G 
Sbjct: 1033 GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG----------PTGDP-GLPGDMGK 1081

Query: 212  PIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
               M  PG    PPG  GP  P   P  P
Sbjct: 1082 KGEMGQPG----PPGHLGPAGPEGAPGSP 1106



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 54/165 (32%), Positives = 66/165 (40%), Gaps = 43/165 (26%)

Query: 89   DTGIARVPLAGAAGGPGVGRAAG-RGVPA--GVPIPQAPAGLAGPVRGVGGPSQQVMTPQ 145
            +TG+ R P  G  G PG   A G RG P   G+P  +   G AGP RG  G         
Sbjct: 1171 ETGLLRAP-PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP-RGPTG--------- 1219

Query: 146  GRGTVAAAAVAATASIAGAPTQYPPGR-GTPPPPVGRATP-PPGIMAPPPGMRPPMGPPI 203
                     +       G P    PG+ G   PP  R +P  PG    PPG  PP    I
Sbjct: 1220 ---------IEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPG----PPG--PPGSHVI 1264

Query: 204  GLPPARGTPIGMPPPGMRPPP--PGIRGPP-------PPGMRPPR 239
            G+   +G+   M  PG + PP   G  GPP        PG+  PR
Sbjct: 1265 GIKGDKGS---MGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPR 1306



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 30/171 (17%)

Query: 84   GPPPKDTGIARVPLAGAAGGPG----VGRAAGRGVPAGVPIPQAPAGLAGPV-----RGV 134
            GPP +D  I  +   GA G PG     G    RG P G+P  +   G  G       +G 
Sbjct: 883  GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSP-GIPGVKGQRGTPGAKGEQGDKGN 941

Query: 135  GGPSQ--QVMTPQG----RGTVAAAAVAATASIAGAP----TQYPPGRGTPPPPVG--RA 182
             GPS+   V+  +G    +G            + G P     +  PG   PP P G   +
Sbjct: 942  PGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 183  TPPPGIMAPPPGMR--PPMGPPIGLPPARGT--PIGMPPPGMRPPPPGIRG 229
            T  PG     PG+R  P     +G+P ++G    +G P    RP  PGI G
Sbjct: 1002 TGNPG----EPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 51/207 (24%), Positives = 67/207 (32%), Gaps = 57/207 (27%)

Query: 86  PPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPV-------------- 131
           P  + G+         G PG+    G     G+P  Q  AGL G                
Sbjct: 468 PKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGF 527

Query: 132 ------RGVGGPSQQVMTPQGR-------------GTVAAAAVAATASIAGAPTQYPPG- 171
                  G+ G   + + P+G+             G      +  T  + G P   P G 
Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG--PKGE 585

Query: 172 ---------RGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPG--- 219
                    +G P  P    +P P   A PPG  P   P  GL   +G P    PPG   
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEP--GLQGTQGVPGAPGPPGEAG 643

Query: 220 ------MRPPPPGIRGPP-PPGMRPPR 239
                 +  P PG  GPP PPG   P+
Sbjct: 644 PRGELSVSTPVPGPPGPPGPPGHPGPQ 670



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 49/157 (31%), Positives = 57/157 (36%), Gaps = 26/157 (16%)

Query: 99  GAAGGPGV-GRAAGRGVPA-----GVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAA 152
           GA G PG+ G+    GVP      GV   +   GL G   G+ G    +  P  RG    
Sbjct: 288 GAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE-DGIKGQKGDIGPPGFRGPTEY 346

Query: 153 AAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLP------ 206
                     G P   PPG      P G  + PPG+   P   RP +    G P      
Sbjct: 347 YDTYQEKGDEGTPG--PPGPRGARGPQG-PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK 403

Query: 207 --------PARGTPIGMPPPGMRPPPPGIRGPP-PPG 234
                    A GTP G P     P  PG  GPP PPG
Sbjct: 404 GERGRPGKDAMGTP-GSPGCAGSPGLPGSPGPPGPPG 439



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 51/181 (28%), Positives = 63/181 (34%), Gaps = 32/181 (17%)

Query: 83   EGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVM 142
            +G P    G    P  G  G PG+    G+    G P P    G AGP    G P    +
Sbjct: 1053 KGEPGYSEGTRPGP-PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGL 1111

Query: 143  T----PQG-------RGTVAAAAVAATASIAGAPTQYPP-------GRGTPPPPVGRATP 184
                 P G       +G +    +     + G P    P       GR   P P G    
Sbjct: 1112 PGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE-KG 1170

Query: 185  PPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPP-PGMRPP--------PPGIRG-PPPPG 234
              G++  PPG R   G   G    RG P G P  PG +          P GI G P PPG
Sbjct: 1171 ETGLLRAPPGPRGNPGAQ-GAKGDRGAP-GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 235  M 235
            +
Sbjct: 1229 L 1229



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 47/162 (29%), Positives = 57/162 (35%), Gaps = 21/162 (12%)

Query: 95  VPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPV-RGVGGPSQQVMTPQGRGTVAAA 153
           + L G  G PG     G   P G P    P G  GP  R + GP      P   G     
Sbjct: 770 IGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQ 829

Query: 154 AVAATASIAGAP-------TQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP---- 202
                    G P       + +P   G+P  P  +    P      PG    +GPP    
Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889

Query: 203 ----IGLPPARGTPIGMPPPGMRPPPPGIRGPPP-PGMRPPR 239
               +G P A G P    PPG  P  PG RG P  PG++  R
Sbjct: 890 VIGMMGFPGAIGPP---GPPG-NPGTPGQRGSPGIPGVKGQR 927



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 31/175 (17%)

Query: 87   PKDTGIARVPLAGAAGGPGV-------GRAAGRGVPA-----GVPIPQAPAGLAGPVRGV 134
            P   G+ R    G  G PG+       G    RG P      G P      G+ G    +
Sbjct: 841  PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900

Query: 135  G--GPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPP----VGRATPPPGI 188
            G  GP     TP  RG+     V       GA  +    +G P P     V      PG+
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD-KGNPGPSEISHVIGDKGEPGL 959

Query: 189  --MAPPPGMRPPMGPP--IGLPPARGTPIGMPPPGMR--------PPPPGIRGPP 231
               A  PG +   G P   GL   +G P    PPG R        P  PG+RG P
Sbjct: 960  KGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIP 1014



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 49/167 (29%), Positives = 60/167 (35%), Gaps = 32/167 (19%)

Query: 99  GAAGGPGVGRAAGRGVPAGVPIPQAPAGLAG--------PVRGVGGPSQQVMTPQGRGTV 150
           G  G PG     G   P G+P PQ P G  G         VRG+ G      +P   GT 
Sbjct: 52  GFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTP 111

Query: 151 AAAAVAATASIAG-APTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPI------ 203
                     + G + ++   G    P  +G     PGI     G++   G P       
Sbjct: 112 GNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGY----PGIPG-AAGLKGQKGAPAKEEDIE 166

Query: 204 -------GLPPARGTPIGMPPPGMRPPPPGIRGPPP----PGMRPPR 239
                  GLP A G P G+P P   P P G  GPP     PG   PR
Sbjct: 167 LDAKGDPGLPGAPG-PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 50/174 (28%), Positives = 59/174 (33%), Gaps = 35/174 (20%)

Query: 97  LAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVA 156
           L GA G P V    G G P G P  +  +G  G + G+ G      TP   G        
Sbjct: 737 LPGAKGEPAVAMPGGPGTP-GFPGERGNSGEHGEI-GLPGLPGLPGTPGNEGLDGPRGDP 794

Query: 157 ATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP----------IGLP 206
                 G   Q PPGR    P   +  P    +    G R   GP            G P
Sbjct: 795 GQPGPPG--EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFP 852

Query: 207 PARGTPIGMP-------PPGMR--PPPPGIRGPP-----------PPGMRPPRP 240
              G+P G+P       P G R  P  PGI GPP           P  + PP P
Sbjct: 853 GETGSP-GIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP 905



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 46/168 (27%), Positives = 57/168 (33%), Gaps = 38/168 (22%)

Query: 97  LAGAAGGPGVGRAAG----RGVPA----------------GVPIPQ---APAGLAGPVRG 133
           L G  G PG+  AAG    +G PA                G P PQ    P G  GPV  
Sbjct: 137 LPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196

Query: 134 VGGPS----QQVMTPQG-RGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGI 188
            G P        M P+G +G +    +             PPG   PP  V      P  
Sbjct: 197 PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPG---PPGTVIVTLTGPDN 253

Query: 189 MAPPPGMRPPMGPPIGLPPARGTPIGMPPPGM-----RPPPPGIRGPP 231
                G +   G  +G P   G P G+P          P  PG++G P
Sbjct: 254 RTDLKGEKGDKG-AMGEPGPPG-PSGLPGESYGSEKGAPGDPGLQGKP 299



 Score = 27.7 bits (60), Expect = 9.2
 Identities = 46/188 (24%), Positives = 62/188 (32%), Gaps = 36/188 (19%)

Query: 86  PPKDTGIARVPLAGAAGGPG-------VGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPS 138
           PP   G    P A    GP        +G    RGV  G+  P  P G    +  + GP 
Sbjct: 196 PPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK-GLTGPPGPPGTV--IVTLTGPD 252

Query: 139 QQVMTPQGRGTVAAAAVAATASIAGAPTQ-YPPGRGTPPPPVGRATP-PPGIMAPP--PG 194
            +      +G   A         +G P + Y   +G P  P  +  P   G+   P   G
Sbjct: 253 NRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG 312

Query: 195 MRPPMGPP--IGLPPARGTPIGMPPPGMRPP--------------------PPGIRGPPP 232
           ++   G P  +G    +G    + PPG R P                    P G RGP  
Sbjct: 313 VKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQG 372

Query: 233 PGMRPPRP 240
           P   P  P
Sbjct: 373 PSGPPGVP 380


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 43/113 (38%), Positives = 53/113 (46%), Gaps = 14/113 (12%)

Query: 128 AGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPG 187
           + P+     P   V+TP G   VAA +V A       P  +PP    PPPP     P PG
Sbjct: 648 SAPITSADCPKPMVVTP-GAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPP----PPQPG 702

Query: 188 IMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
              PPP   PP  PP   PP     + +PPP + P PPG+   PPP + PP P
Sbjct: 703 FPMPPP--LPPPPPP---PPPAHPAVTVPPPPL-PAPPGV---PPPPILPPLP 746



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 39/116 (33%), Positives = 43/116 (37%), Gaps = 17/116 (14%)

Query: 124 PAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAG------APTQYPPGRGTPPP 177
           P G  G   G  GP  +   PQ   T A     A A+ A       +P Q P     PPP
Sbjct: 353 PFGAVGGTGGSSGPPFKAQ-PQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPP 411

Query: 178 PVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPP 233
               AT   G        R P  PP  LPPA   P+    PG  P      GPPPP
Sbjct: 412 EEPTATAAFGARDSGEFRRAPAPPP--LPPAE--PLAKEKPGTPP------GPPPP 457



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 54/203 (26%), Positives = 69/203 (33%), Gaps = 50/203 (24%)

Query: 79   SMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAG--------LAGP 130
            S     P     G+ R P    +  P     +G   P  +P+   P G        LA P
Sbjct: 1366 SYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSG---PLLLPVCPLPTGRRDERSGPLASP 1422

Query: 131  VRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTP----PPPVGRA---- 182
            V    G    +  P        A + A A    APT  PP    P    PPP+ R     
Sbjct: 1423 VLLETGLPLPLPLPLPLPLALPAVLRAQAR---APTPLPPLLPAPLASCPPPMKRKPGRP 1479

Query: 183  --TPPPGIMAPPPGMRPPMGPPIG-----LPPARGTP-------------------IGMP 216
              +PP  +    P +RPP G  +G     LP    TP                   I  P
Sbjct: 1480 RRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAP 1539

Query: 217  PPGMRPPPPGIRGPPPPGMRPPR 239
            PP + P PP    PPPP + P +
Sbjct: 1540 PPPLPPQPP--PPPPPPPVEPTK 1560



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 29/101 (28%), Positives = 36/101 (35%), Gaps = 10/101 (9%)

Query: 145 QGRGTVAAAAVAATASIAGAPTQYPPGRG-----TPPPPVGRATPPPGIMAPPPGMRPPM 199
           +G   +   AV  T   +G P +  P        TPPP   +ATP PG  +      P  
Sbjct: 347 RGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPP--AQATPAPGFKS---AFSPYQ 401

Query: 200 GPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
            P    PP    P      G R      R P PP + P  P
Sbjct: 402 TPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEP 442



 Score = 34.3 bits (77), Expect = 0.099
 Identities = 31/99 (31%), Positives = 37/99 (37%), Gaps = 22/99 (22%)

Query: 162  AGAPTQYPPGRGTPPPPVGRATPP--------PGI-------MAPPPGM-----RPPMGP 201
            A AP + P     PP PVG   P         PG+       ++P P       RPP+ P
Sbjct: 1197 AVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSP 1256

Query: 202  PIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
                 P     +   PP M P P     PPP   RPP P
Sbjct: 1257 ERA--PEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSP 1293



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 42/165 (25%), Positives = 55/165 (33%), Gaps = 34/165 (20%)

Query: 96   PLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGG----------PSQQVMTP- 144
            PL+G + G  +      G P   P P       G  R  G           PS  ++ P 
Sbjct: 1345 PLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPV 1404

Query: 145  ----QGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMG 200
                 GR    +  +A+       P     G   P P      P P  +A P  +R    
Sbjct: 1405 CPLPTGRRDERSGPLAS-------PVLLETGLPLPLP-----LPLPLPLALPAVLRAQAR 1452

Query: 201  PPIGLPPARGTPIGMPPPGMRPPPPGIRGPPP-------PGMRPP 238
             P  LPP    P+   PP M+  P   R  PP       P +RPP
Sbjct: 1453 APTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPP 1497



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 41/163 (25%), Positives = 57/163 (34%), Gaps = 19/163 (11%)

Query: 81  TVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVP-IPQAPAGLAGPVRGVGGPSQ 139
           T  GPPP DT    +      G P  G +       G P +  +PAG   P   +    +
Sbjct: 450 TPPGPPPPDTNSMEL-----GGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIE 504

Query: 140 QVMTPQGRGTVAAAAVAATASIA--GAPTQYPPGRGTPPPPVGRATPPPGIMAP-PPGMR 196
            ++  Q    +      +   +   G+P      + +P  P G     PG   P PP  R
Sbjct: 505 MLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFG-TNSQPGFRGPTPPSSR 563

Query: 197 PPMGPPIGLPPARGTPIGMPPP------GMRPPPPGIRGPPPP 233
           P      GL     TP+           G+ P PP   GPP P
Sbjct: 564 PSS---TGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDP 603



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 46/151 (30%), Positives = 57/151 (37%), Gaps = 20/151 (13%)

Query: 95   VPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAG-PVRGVGGPSQQVMTPQGRGTVAAA 153
            +PL      P V RA  R  P  +P P  PA LA  P      P +   +P    ++   
Sbjct: 1435 LPLPLPLALPAVLRAQARA-PTPLP-PLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP 1492

Query: 154  AVAATASIA-GAPTQYPPGRGTPPPPVGRATPPP----------GIMAPPPGMRPPMGPP 202
             V   A  A G      PG+  P  PV  +T  P          GI APPP + P   PP
Sbjct: 1493 LVRPPAGAALGRELLLLPGQ--PQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPP 1550

Query: 203  IGLPPARGTPIGMPPPGMRPP----PPGIRG 229
               PP   T +       + P    PPG RG
Sbjct: 1551 PPPPPVEPTKLPFKELDNQWPSEAIPPGPRG 1581



 Score = 28.9 bits (63), Expect = 4.2
 Identities = 32/142 (22%), Positives = 45/142 (31%), Gaps = 18/142 (12%)

Query: 115  PAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVA----AAAVAATASIAGAPTQYPP 170
            P+ +  P  P G+  P      P +  ++ +G   ++    A  V A   ++        
Sbjct: 1204 PSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHD 1263

Query: 171  GRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRG- 229
                P PP+    P    + PP   RPP  PP         P   P P     PP   G 
Sbjct: 1264 LEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGL 1323

Query: 230  -------------PPPPGMRPP 238
                         P  PG  PP
Sbjct: 1324 CGSLAKSQSTETVPATPGGEPP 1345


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 54/165 (32%), Positives = 60/165 (36%), Gaps = 25/165 (15%)

Query: 85  PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTP 144
           PPP+D+    V   G    PGVG A     PA    P A    +G   G           
Sbjct: 101 PPPQDSS-KPVVAQGPGPAPGVGSAP----PASSSAPPATPPTSGAPPG----------- 144

Query: 145 QGRGTVAAAAVAATASIAGAPTQYPPGRGTP-PPPVGRATPPPGIMAPPPGMRPPMGPPI 203
            G G       A T++  GAP   PP  G P  PP     PPP    P PG  P  GP  
Sbjct: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP 204

Query: 204 GLP--------PARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
           G P        P  G   G+  PG  P PP   G  P G R   P
Sbjct: 205 GGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP 249



 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 50/163 (30%), Positives = 58/163 (35%), Gaps = 34/163 (20%)

Query: 99  GAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAAT 158
           G  GG G G    R  P G+ + Q   G  GP  G  GP   +  P              
Sbjct: 20  GGGGGRG-GLHDFRSPPPGMGLNQN-RGPMGPGPGQSGPKPPIPPPPPHQQQQQP----- 72

Query: 159 ASIAGAPTQYPPGRGTP-------PPPVGRATPPP-------GIMAPPPGMRPPMG--PP 202
                 P Q PP +  P       P P  +  PPP        ++A  PG  P +G  PP
Sbjct: 73  ------PPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPP 126

Query: 203 I--GLPPARGTPIGMPP---PGMRPPPPGIRGPPPPGMRPPRP 240
                PPA     G PP   PG  P PP      PPG  PP P
Sbjct: 127 ASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTP 169



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 37/120 (30%), Positives = 41/120 (34%), Gaps = 32/120 (26%)

Query: 79  SMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPS 138
           S  V   PP+  G    P A    GPG  +  G G P G  +P       GP  G GGP 
Sbjct: 171 SSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMP------GGPKPG-GGPG 223

Query: 139 QQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPP----GIMAPPPG 194
             + TP G                      PP RG   P  GR   PP        PPPG
Sbjct: 224 --LSTPGGH-------------------PKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPG 262


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 64.3 bits (155), Expect = 9e-11
 Identities = 59/166 (35%), Positives = 67/166 (40%), Gaps = 24/166 (14%)

Query: 97  LAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGP--VRGVGGPSQQ-----VMTPQG-RG 148
           L GA G PG   A G   P G   P+   GL G   +RG  GPS       +  PQG +G
Sbjct: 729 LPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQG 788

Query: 149 TVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPP--PGMRPPMGPPIGLP 206
                         GAP +     G+    V     PPG M PP  PG   P GP  GLP
Sbjct: 789 LPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPA-GLP 847

Query: 207 -----------PARGTPIGMPPPGMRPPPPGIRGPPPPGM-RPPRP 240
                      P    P G P P + P PPG RGPP  G+  PP P
Sbjct: 848 GHQEVLNLQGPPGPPGPRGPPGPSI-PGPPGPRGPPGEGLPGPPGP 892



 Score = 54.3 bits (129), Expect = 9e-08
 Identities = 53/184 (28%), Positives = 67/184 (36%), Gaps = 47/184 (25%)

Query: 86  PPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGP-----VRGVGGPSQQ 140
           P  + G+  +P  G  G PG     G+    G+  PQ P GL G      ++G  G   +
Sbjct: 753 PRGEQGLTGMP--GIRGPPGPSGDPGK---PGLTGPQGPQGLPGTPGRPGIKGEPGAPGK 807

Query: 141 VMTPQGRGTVAAAAVAATASIAGAPTQYPPG-------------------RGTPPPPVGR 181
           ++T +G   +            G P   PPG                   +G P PP  R
Sbjct: 808 IVTSEGSSMLTVPGPPGPPGAMGPPG--PPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPR 865

Query: 182 ATPPPGIMAPPPGMRPPMGPP-IGLPPARGTP-----------IGMPPPGMRPPPPGIRG 229
             P P I  PP     P GPP  GLP   G P            G P P   P P G +G
Sbjct: 866 GPPGPSIPGPP----GPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQG 921

Query: 230 PPPP 233
           PP P
Sbjct: 922 PPGP 925



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 51/158 (32%), Positives = 58/158 (36%), Gaps = 28/158 (17%)

Query: 99  GAAGGPGVGRAAGRGV--------PAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTV 150
           G AG PG G    RG         P GVP    P G +G   G  GP   V     RG V
Sbjct: 633 GEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS-PGPQGPPGPVGLQGLRGEV 691

Query: 151 AAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARG 210
               V       G     PPG     P   +    P  +   PGMR   G  +G P A+G
Sbjct: 692 GLPGVKGDKGPMG-----PPG-----PKGDQGEKGPRGLTGEPGMRGLPG-AVGEPGAKG 740

Query: 211 TPIGMPPPGMRPP--------PPGIRGPPPPGMRPPRP 240
                 P G + P         PGIRGPP P   P +P
Sbjct: 741 AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKP 778



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 60/208 (28%), Positives = 69/208 (33%), Gaps = 56/208 (26%)

Query: 84  GPPPK----DTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAG---------- 129
           GPP      + G A  P  G  G PGV  + G    +G P PQ P G  G          
Sbjct: 636 GPPGSGEKGERGAAGEP--GPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGL 693

Query: 130 -PVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAP--TQYPPGRGT--PPPPVGRATP 184
             V+G  GP         +G      +     + G P     P  +G   P  P G   P
Sbjct: 694 PGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGP 753

Query: 185 --------PPGIMAPP--------PGMRPPMGPPIGLPPARGTPIGMPPPGM-------- 220
                    PGI  PP        PG+  P GP  GLP   G P     PG         
Sbjct: 754 RGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ-GLPGTPGRPGIKGEPGAPGKIVTSE 812

Query: 221 ---------RPPPPGIRGPP-PPGMRPP 238
                     P PPG  GPP PPG   P
Sbjct: 813 GSSMLTVPGPPGPPGAMGPPGPPGAPGP 840



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 53/181 (29%), Positives = 67/181 (37%), Gaps = 35/181 (19%)

Query: 86   PPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQ 145
            PP   G     L G  G PG   +      +G P P  P G  G  +G  GP       Q
Sbjct: 875  PPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD-QGPPGPRGH----Q 929

Query: 146  GRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPP--PGIM-------------- 189
            G   +   + + ++S  G   Q PPG   P  P G    P  PG +              
Sbjct: 930  GEQGLPGFSTSGSSSF-GLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSST 988

Query: 190  ---APPPGMRPPMGPPIGLPPARGTPIG------MPPPGMRPPPPGIRGPP-PPGMRPPR 239
               + PPG   P GPP G   + G  I       M    +R    G++GPP PPG  PP 
Sbjct: 989  MYVSGPPGPPGPPGPP-GSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPG--PPG 1045

Query: 240  P 240
            P
Sbjct: 1046 P 1046



 Score = 35.8 bits (81), Expect = 0.034
 Identities = 33/119 (27%), Positives = 47/119 (39%), Gaps = 17/119 (14%)

Query: 74   GENLVSMTVEGPP-------PK-DTGIARVPLA-GAAGGPGVGRAAGRGVPAGVPIPQAP 124
            G +   + ++GPP       PK D G   VP A G   GP  G ++     +G P P  P
Sbjct: 941  GSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGP 1000

Query: 125  AGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRAT 183
             G  G +   G   QQ ++   +     + ++          Q PPG   PP PV   T
Sbjct: 1001 PGPPGSISSSGQEIQQYISEYMQSDSIRSYLSG--------VQGPPGPPGPPGPVTTIT 1051



 Score = 35.8 bits (81), Expect = 0.034
 Identities = 40/141 (28%), Positives = 52/141 (36%), Gaps = 28/141 (19%)

Query: 113  GVPAGVPIPQAPAGLAG-------------PVRGVGGPSQQVMTPQGRGTVAAAAVAATA 159
            G+  G+P P  P GL G               RG+ GP      P   G V ++      
Sbjct: 1142 GISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDL 1201

Query: 160  S--IAGAPTQYPPGRGTPPPPVGRATPP--PGIMAP-----PPGMRPPMGPPIGLPPARG 210
            S  +  A   + PG   PP P G   PP   G +A          R  +   +  P  R 
Sbjct: 1202 SSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRS 1261

Query: 211  TPIGMPPPGMRPPPPGIRGPP 231
              +G  PPG    PPG +GPP
Sbjct: 1262 FIVG--PPG----PPGPQGPP 1276



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 46/165 (27%), Positives = 53/165 (32%), Gaps = 42/165 (25%)

Query: 98   AGAAGGPGV-GRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVA 156
            AG+ G  G  G AAG   P G  I        GP  G G  ++  M   G G +  A  A
Sbjct: 1318 AGSLGAGGAFGEAAGDRGPYGTDI--------GPGGGYGAAAEGGMYA-GNGGLLGADFA 1368

Query: 157  ATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP-------------- 202
                      +            G A    G    PPG   P GPP              
Sbjct: 1369 GDLDYNELAVRVSESMQRQGLLQGMAYTVQG----PPGQPGPQGPPGISKVFSAYSNVTA 1424

Query: 203  -----------IGLPPARGTPIGMP-PPGMRPP--PPGIRGPPPP 233
                       I  PP +   +G P P G R P  PPG  GPP P
Sbjct: 1425 DLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGP 1469


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 58/154 (37%), Positives = 67/154 (43%), Gaps = 18/154 (11%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTP 144
            PP    G   +P  GAAG P V   A    PA V +P APAG   P  G  GPS+Q+   
Sbjct: 962  PPALPPGSQPIPPTGAAGPPAVHGLAV--APASV-VP-APAGSGAPP-GSLGPSEQI--- 1013

Query: 145  QGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIG 204
               G   + A       AGAP       G PPP     +P P     PP M P   P  G
Sbjct: 1014 ---GQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPN-QQTPPSMMPGAVPGSG 1069

Query: 205  LPPARG-TPIGMPPPGMRPPPPGIRGPPPPGMRP 237
             P   G  P+G+ P GM PPPP    PP P + P
Sbjct: 1070 HPGVAGNAPLGL-PFGMPPPPP----PPAPSIIP 1098



 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 50/176 (28%), Positives = 68/176 (38%), Gaps = 17/176 (9%)

Query: 66   VLGLVLLRGENLVSMTVEGPPPKDTGIA-RVPLAGAAGGPGVGRAAGRGVPAGVPIPQAP 124
            V GL +     + +    G PP   G + ++  AG+  GP   + AG   P  VP    P
Sbjct: 983  VHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPP 1042

Query: 125  AGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATP 184
             G  GP      P+QQ       G V  +     A    AP   P G   PPPP   +  
Sbjct: 1043 PGPHGPSPF---PNQQTPPSMMPGAVPGSGHPGVAG--NAPLGLPFGMPPPPPPPAPSII 1097

Query: 185  PPGIMAPPPGMRPPMGPPI-----GLPPARGTPIGMPPPGMRPPPPGIRGPPPPGM 235
            P G +A    +  P  P +      LP A GT   +PPP +   P  +  P  P +
Sbjct: 1098 PFGSLADSISINLPAPPNLHGHHHHLPFAPGT---LPPPNL---PVSMANPLHPNL 1147



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 34/95 (35%), Positives = 38/95 (40%), Gaps = 25/95 (26%)

Query: 165  PTQYPPGRGTPPPPVGRATPPP--GIMAPPPGMRP-PMG---PPIGLPPA---------- 208
            P   PPG   P PP G A PP   G+   P  + P P G   PP  L P+          
Sbjct: 962  PPALPPG-SQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTA 1020

Query: 209  ---RGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP 240
               +  P G P PG  PP     G PPPG   P P
Sbjct: 1021 GPQQQQPAGAPQPGAVPP-----GVPPPGPHGPSP 1050



 Score = 37.0 bits (84), Expect = 0.015
 Identities = 37/136 (27%), Positives = 51/136 (37%), Gaps = 27/136 (19%)

Query: 85   PPPKDTGIARVPLAGAAGGPGVGRAAGRGV----------PAGVPIPQAPAGLAGPVRG- 133
            PPP     + +P    A    +   A   +          P  +P P  P  +A P+   
Sbjct: 1087 PPPPPPAPSIIPFGSLADSISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPN 1146

Query: 134  ----VGGPSQQVMTPQGRGTVAAAAVAATASIAG--APTQYP-PGRGTPPPPVGRATPPP 186
                   PS   + P G G+ AA + A  A++ G   P+  P P  GTP PP        
Sbjct: 1147 LPATTTMPSSLPLGP-GLGSAAAQSPAIVAAVQGNLLPSASPLPDPGTPLPP-------- 1197

Query: 187  GIMAPPPGMRPPMGPP 202
               AP PG   P+ PP
Sbjct: 1198 DPTAPSPGTVTPVPPP 1213


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 61/177 (34%), Positives = 66/177 (37%), Gaps = 25/177 (14%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVM 142
           +GPPP+       P  G  G    G     G P G P PQ      GP    G P     
Sbjct: 132 QGPPPRPGKPEGPPPQG--GNQSQGPPPRPGKPEGPP-PQGGNQSQGPPPHPGKPEGP-- 186

Query: 143 TPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGI-----MAPPPGMRP 197
            PQG G  +           G P Q       PPP  G+   PP         PPP    
Sbjct: 187 PPQG-GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGK 245

Query: 198 PMGPPIG------LPPARGTPIGMPPPGMRP----PPPG--IRGPPPP--GMRPPRP 240
           P GPP         PP  G P G PPPG  P    PPP    +GPPPP  G RP RP
Sbjct: 246 PQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRP 302



 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 54/163 (33%), Positives = 62/163 (38%), Gaps = 12/163 (7%)

Query: 83  EGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVM 142
           +GPPP+       P  G  G    G     G P G P PQ      GP    G P     
Sbjct: 153 QGPPPRPGKPEGPPPQG--GNQSQGPPPHPGKPEGPP-PQGGNQSQGPPPRPGKPEGP-- 207

Query: 143 TPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPP 202
            PQG G  +           G P+Q       PPP  G+   PP      P   PP G P
Sbjct: 208 PPQG-GNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRP 266

Query: 203 IGLPPARGTPIG-MPPP-----GMRPPPPGIRGPPPPGMRPPR 239
            G PP  G P   +PPP     G  PPP G R   PP  +PP+
Sbjct: 267 QGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ 309



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 52/162 (32%), Positives = 58/162 (35%), Gaps = 31/162 (19%)

Query: 106 VGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAP 165
           V +     V +G P  + P G   P R    P +    P+GR               G P
Sbjct: 23  VSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGK----PEGRPPQGGNQSQGPPPRPGKP 78

Query: 166 TQYPPGRGT----PPPPVGR--ATPPPG---IMAPPPGMRPPMGPP-------IGLPPAR 209
              PP  G     PPP  G+    PP G      PPP    P GPP        G PP  
Sbjct: 79  EGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP 138

Query: 210 GTPIGMPPPGMR-----PPPPG-IRGPPPPGMR-----PPRP 240
           G P G PP G       PP PG   GPPP G       PP P
Sbjct: 139 GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHP 180


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.142    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,112,677
Number of Sequences: 37866
Number of extensions: 1569859
Number of successful extensions: 40115
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 923
Number of HSP's successfully gapped in prelim test: 1727
Number of HSP's that attempted gapping in prelim test: 10048
Number of HSP's gapped (non-prelim): 13419
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press