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Search of human proteins with 12738834
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12738834 PRAME family member 2 [Homo sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|12738834 PRAME family member 2 [Homo sapiens] 974 0.0
gi|12738831 PRAME family member 1 [Homo sapiens] 900 0.0
gi|66954681 PRAME family member 13 [Homo sapiens] 887 0.0
gi|153792140 PRAME family member 14 [Homo sapiens] 777 0.0
gi|154800493 PRAME family member 22 [Homo sapiens] 545 e-155
gi|194306635 PRAME family member 19 [Homo sapiens] 545 e-155
gi|153791443 PRAME family member 18 [Homo sapiens] 541 e-154
gi|194306638 PRAME family member 3 [Homo sapiens] 540 e-154
gi|157426839 PRAME family member 17 [Homo sapiens] 531 e-151
gi|194018546 PRAME family member 10 [Homo sapiens] 531 e-151
gi|113865933 PRAME family member 16 [Homo sapiens] 529 e-150
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ... 492 e-139
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 459 e-129
gi|124249372 PRAME family member 12 [Homo sapiens] 448 e-126
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ... 446 e-125
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 437 e-122
gi|59676587 PRAME family member 8 [Homo sapiens] 437 e-122
gi|59676593 PRAME family member 7 [Homo sapiens] 434 e-122
gi|153792112 PRAME family member 20 [Homo sapiens] 407 e-114
gi|153945800 PRAME family member 21 [Homo sapiens] 407 e-114
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 401 e-112
gi|148356236 PRAME family member 15 [Homo sapiens] 397 e-110
gi|61102721 PRAME family member 9 [Homo sapiens] 397 e-110
gi|61696142 PRAME family member 5 [Homo sapiens] 397 e-110
gi|58219004 PRAME family member 6 [Homo sapiens] 396 e-110
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 390 e-108
gi|59958373 PRAME family member 4 [Homo sapiens] 387 e-107
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 341 7e-94
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 341 7e-94
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 341 7e-94
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 974 bits (2519), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL
Sbjct: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ
Sbjct: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 900 bits (2326), Expect = 0.0
Identities = 444/474 (93%), Positives = 452/474 (95%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLF EAFSRRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPL SLMKTLHLE LKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPE SKRQTAEDCPR GEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CCSKLVNYLTPIKYLRKSLKIIY+NSI ELEI N WP LIRKL CYLKEMK L KLVFS
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
RCHHYTSDNEL+G LV +F+SVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
T G LLEED+KCLSQ+PSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL+TL+LEGCQ
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILP LS CSQLTTFYFG NCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRVNWEIFTPLRAELMCTLRE RQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 887 bits (2292), Expect = 0.0
Identities = 439/474 (92%), Positives = 449/474 (94%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLF EAF RRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPL SLMKTLHLE LKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPE MSKRQTAEDCPR GEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CCSKLVNYLTPIK+LRKSLKIIY+NSI +LEI N WP LIRKL CYLKEMK L KLVFS
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
RCHH SDNELEG LVT+F+SVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL
Sbjct: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
T G LLEED+KCLSQ+PSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETL+LEGCQ
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILPGLS CSQLTTFYFG NCMS+ ALKDLLRHTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRV+WEIF LRAELMCTLRE RQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|153792140 PRAME family member 14 [Homo sapiens]
Length = 426
Score = 777 bits (2007), Expect = 0.0
Identities = 395/474 (83%), Positives = 403/474 (85%), Gaps = 48/474 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLF EAF RRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPL SLMKTLHLE LKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPE MSKRQTAEDCPR GEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CCSKLVNYLTPIK+LRKSLKIIY+NSI +LEI N WP LIRKL CYLKEMK L KLVFS
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
R CLQNPLENLEL
Sbjct: 241 R------------------------------------------------CLQNPLENLEL 252
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
T G LLEED+KCLSQ+PSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETL+LEGCQ
Sbjct: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILPGLS CSQLTTFYFG NCMS+ ALKDLL HTSGLSKLSLETYPAPEESLN
Sbjct: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRV+WEIF LRAELMCTLRE RQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 545 bits (1405), Expect = e-155
Identities = 287/473 (60%), Positives = 340/473 (71%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF EAF+ R + L VMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPL SLMKT LE L +++G+ LL QK RPRRWKLQVL+LRDVDENFW W GA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PEAMSKRQT EDCPRTGE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC+K+VNY I R L+ +Y +SI LEI N CWP +I + YL +M+ L KL S
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Y ++ + LV F+SV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L L
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
T G L + DLKCL ++PSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I S+L ILP LSCCS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
RV E+ TPL+AELM LRE R+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 545 bits (1404), Expect = e-155
Identities = 289/473 (61%), Positives = 340/473 (71%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF EAF+ R + L VMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPL SLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PEAMSKRQT EDCPRTGE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC+K+VNY I R L+ +Y +SI LEI N CWP ++ ++ YL +MK L KL S
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Y E +G LV F+SVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
T G+L EEDLKCL +PSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I YS+L ILP LS CS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
+ RV E+ TPL+AELM LRE R+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 541 bits (1394), Expect = e-154
Identities = 288/473 (60%), Positives = 339/473 (71%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF EAF+ R + L VMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPL SLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PEAMSKRQT EDCPRTGE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC+K+VNY I R L+ +Y +SI LEI N CWP ++ ++ YL +MK L KL S
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Y E +G LV F+SVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
T G+L EEDLKCL +PSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I S+L ILP LS CS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
+ RV E+ TPL+AELM LRE R+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 540 bits (1392), Expect = e-154
Identities = 286/473 (60%), Positives = 339/473 (71%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF EAF+ R + L VMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPL SLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PEAMSKRQT EDCPRTGE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC+K+VNY I R L+ +Y +SI LEI N CWP +I + YL +M+ L KL S
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Y ++ + LV F+SV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L L
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
T G L + DLKCL ++PSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I S+L ILP LSCCS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
RV E+ TPL+AELM LRE R+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 531 bits (1368), Expect = e-151
Identities = 281/477 (58%), Positives = 337/477 (70%), Gaps = 8/477 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +F EA S RHF+ L +MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL SLMKT HLE L+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSC PEAMSKRQT ED PRTGEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC+K+ NY P R LK +Y +SI ELEI C + K YL +M L KL +
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 RCHHYTSDNEL----EGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
+ D+EL + V FL L + Q+L I+ I+ HLE L+RCL+NPL
Sbjct: 241 ----FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
Query: 297 NLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVL 356
L ++D++CLSQ+PSL LK L+L ++L++ +LEPLGALLEK+AA+LE L L
Sbjct: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
Query: 357 EGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPE 416
+ CQI SQL +LP LS CSQLTTFYF N S +ALKDLL HT GLSKL LE YPAP
Sbjct: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
Query: 417 ESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
E L++ VNWEI P+RAELMCTLRE RQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 531 bits (1367), Expect = e-151
Identities = 278/473 (58%), Positives = 334/473 (70%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +F EAFS R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL SLMKTLHLE L+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PEAMSKRQT EDCPR GEHQPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CCSK+ NY P R L+ IY +SI ELE+ C + K YL +M L +L +
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
+ ++ + S FL L + Q+L IK I+ HLE L+R L+NPL
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
+ L + D++CLSQ+PSL LK L L ++L++ LEPLG LLEK+AA+L+TLVL+ C+
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I QL +LP LS CSQLTTF F N S++ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
VNWEI TP+RAELM TLRE RQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 529 bits (1363), Expect = e-150
Identities = 280/477 (58%), Positives = 336/477 (70%), Gaps = 8/477 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +F EA S RHF+ L +MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL SLMKT HLE L+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSC PEAM KRQT ED PRTGEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC+K+ NY P R LK +Y +SI ELEI C + K YL +M L KL +
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 RCHHYTSDNEL----EGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
+ D+EL + V FL L + Q+L I+ I+ HLE L+RCL+NPL
Sbjct: 241 ----FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
Query: 297 NLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVL 356
L ++D++CLSQ+PSL LK L+L ++L++ +LEPLGALLEK+AA+LE L L
Sbjct: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
Query: 357 EGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPE 416
+ CQI SQL +LP LS CSQLTTFYF N S +ALKDLL HT GLSKL LE YPAP
Sbjct: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
Query: 417 ESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
E L++ VNWEI P+RAELMCTLRE RQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 492 bits (1267), Expect = e-139
Identities = 264/473 (55%), Positives = 312/473 (65%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +F EAFS R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL SLMKT HLE L+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PEAMSKRQT EDCPR GE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CCSK+ NY P R L+ IY +SI ELE+ C + K YL +M L +L F
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
R L+NPL
Sbjct: 241 R------------------------------------------------YLKNPLGAFIF 252
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
+ L + D++CLSQ+PSL LK L L ++L++ +LEPLG LLEK+AA+L+TLVL+ C+
Sbjct: 253 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I QL +LP LS CSQLTTF F N S++ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
VNWEI TP+RAELM TLRE RQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 459 bits (1182), Expect = e-129
Identities = 258/476 (54%), Positives = 315/476 (66%), Gaps = 4/476 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF EAF+ R + L VMVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPL SLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PEAMSKRQT EDCPRTGE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC+K+VNY I R L+ +Y +SI LEI N CWP +I + YL +M+ L KL S
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
Query: 241 -RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
C + S + E + FT+ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 241 DGCRYLLSSDSQE--QIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 298
Query: 300 LTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGC 359
+T LLE DLK LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+ C
Sbjct: 299 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 358
Query: 360 QIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESL 419
I SQ++AILP LS C +L TF F N +S+ L++LL HT L L LE YPAP ES
Sbjct: 359 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESY 418
Query: 420 NSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W FT +RAELM +R+ R PKRI G CP CG+ +LE CC
Sbjct: 419 GADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 448 bits (1152), Expect = e-126
Identities = 255/483 (52%), Positives = 322/483 (66%), Gaps = 14/483 (2%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS+QAPPRLLELA QSLLRD+AL+I +EELPR L+ PLF EAF+RR +TLT MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPL SLMK+ +LE +A+LEGL LL QK RPRRWKLQVLDLR+VDENFW W GA
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALS PEA+SKR+TA +CPR G QPL V +D+C K DECL + +W QR+GL+H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWP---HLIRKLYCYLKEMKTLCKL 237
CC +L + I + + L + ++ I E+E+ C P ++ + YL +M+ L KL
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235
Query: 238 VFSRCHHYTS-DNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
V H + + V +FTS FL+L++ Q L + ++F GHL+QL+RCLQ PLE
Sbjct: 236 VLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLE 295
Query: 297 NLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVL 356
+ +T L E DLK LS PS+ LK L+L + L S EPL LLE+ A+L+TL L
Sbjct: 296 TVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDL 355
Query: 357 EGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPE 416
E C I SQLSAILP LS CSQL+TF F N +S+ AL++LLRHT GLSKLSLE YPAP
Sbjct: 356 EDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
Query: 417 ESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELE-----LH 471
ES ++ + W F+ L AELM TLR+ RQPK I PCP CG S +LE L+
Sbjct: 416 ESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLN 475
Query: 472 LCC 474
CC
Sbjct: 476 ACC 478
>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 446 bits (1148), Expect = e-125
Identities = 254/484 (52%), Positives = 300/484 (61%), Gaps = 70/484 (14%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +F EAFS R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL SLMKT HLE L+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PEAMSKRQT EDCPR GE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CCSK+ NY P R L+ IY +SI ELE+ C + K YL +M L +L F
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 R-----------CHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIR 289
R Y +D ++E S + L L+ L++ I ++ HLE L
Sbjct: 241 RYLKNPLGAFIFSDAYLADRDME------CLSQYPSLSQLKELRLIHILMWTTHLEPL-- 292
Query: 290 CLQNPLENLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAA 349
G LLE K+AA
Sbjct: 293 -------------GVLLE--------------------------------------KVAA 301
Query: 350 SLETLVLEGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSL 409
+L+TLVL+ C+I QL +LP LS CSQLTTF F N S++ALKDLLRHT GLSKL L
Sbjct: 302 TLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGL 361
Query: 410 ETYPAPEESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELE 469
E YPAP ESL+ VNWEI TP+RAELM TLRE RQPKRIF GP PCP+CGS PSE+++
Sbjct: 362 ELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVD 421
Query: 470 LHLC 473
HLC
Sbjct: 422 FHLC 425
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 437 bits (1123), Expect = e-122
Identities = 257/481 (53%), Positives = 322/481 (66%), Gaps = 17/481 (3%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LF EAFSRR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPL SLMK+ HLE LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPEA+S++QTA++CP TG QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWP---HLIRKLYCYLKEMKTLCKL 237
CC +L + PI + + L ++ ++ I E+E+ C P + K YL +M+ L KL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 238 VF-----SRCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQ 292
V S C DN+ G + RFTS FL+L++ Q L + ++F GHL+QL+RCLQ
Sbjct: 236 VLFNIRASAC--IPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQ 291
Query: 293 NPLENLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 352
LE + +T L E DLK LS PS+ LK L+L V L S EPL LLE++ A+L+
Sbjct: 292 ASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQ 351
Query: 353 TLVLEGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETY 412
TL LE C I SQLSAILP LS CSQL+TF F N +S+ AL++LLRHT GLSKLSLE Y
Sbjct: 352 TLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELY 411
Query: 413 PAPEESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHL 472
PAP ES ++ + W F L AELM TLR+ RQPK I PCP CG S +LE
Sbjct: 412 PAPLESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSH 471
Query: 473 C 473
C
Sbjct: 472 C 472
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 437 bits (1123), Expect = e-122
Identities = 257/481 (53%), Positives = 322/481 (66%), Gaps = 17/481 (3%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LF EAFSRR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPL SLMK+ HLE LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPEA+S++QTA++CP TG QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWP---HLIRKLYCYLKEMKTLCKL 237
CC +L + PI + + L ++ ++ I E+E+ C P + K YL +M+ L KL
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 238 VF-----SRCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQ 292
V S C DN+ G + RFTS FL+L++ Q L + ++F GHL+QL+RCLQ
Sbjct: 236 VLFNIRASAC--IPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQ 291
Query: 293 NPLENLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 352
LE + +T L E DLK LS PS+ LK L+L V L S EPL LLE++ A+L+
Sbjct: 292 ASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQ 351
Query: 353 TLVLEGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETY 412
TL LE C I SQLSAILP LS CSQL+TF F N +S+ AL++LLRHT GLSKLSLE Y
Sbjct: 352 TLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELY 411
Query: 413 PAPEESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHL 472
PAP ES ++ + W F L AELM TLR+ RQPK I PCP CG S +LE
Sbjct: 412 PAPLESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSH 471
Query: 473 C 473
C
Sbjct: 472 C 472
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 434 bits (1116), Expect = e-122
Identities = 256/481 (53%), Positives = 321/481 (66%), Gaps = 17/481 (3%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LF EAFSRR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPL SLMK+ HLE LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPEA+S++QTA++CP TG QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWP---HLIRKLYCYLKEMKTLCKL 237
CC +L + PI + + L ++ ++ I E+E+ C P + K YL +M+ L KL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 238 VF-----SRCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQ 292
V S C DN+ G + RFTS FL+L++ Q L + ++F GHL+QL+RCLQ
Sbjct: 236 VLFNIRASAC--IPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQ 291
Query: 293 NPLENLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 352
LE + +T L E DLK LS PS+ LK L+L V L S EPL LLE++ A+L+
Sbjct: 292 ASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQ 351
Query: 353 TLVLEGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETY 412
TL LE C I SQLSAILP LS CSQL+TF F N +S+ AL++LLRHT GLSKLSLE Y
Sbjct: 352 TLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELY 411
Query: 413 PAPEESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHL 472
PAP ES ++ + W F L AELM T R+ RQPK I PCP CG S +LE
Sbjct: 412 PAPLESYDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSH 471
Query: 473 C 473
C
Sbjct: 472 C 472
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 407 bits (1047), Expect = e-114
Identities = 234/474 (49%), Positives = 295/474 (62%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRD+AL+IS +EELP L+ PLF EAFSRRH + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL SLMK E +A+L+GL LLT + R RRWKLQVLDL+DV ENFW W A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A C P AM R+ +DCPR QPL VFID+CLK DE LF WV QR GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC KL +R LK + ++ I E+E++ ++ + YL +M+ L KLV S
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
E + VT+FT+ FL+L LQ L + ++F GHL+Q++ CL+ L L +
Sbjct: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
T LLE DLK LS++PS+G LK L+LS L SL PL LLEK+AA+LE L L+ C
Sbjct: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I SQ++AILP LS C +LTTF F N +S L++LL HT L+ L LE YPAP ES +
Sbjct: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
V F L AELM +R R+P+RI CP CG+ +LE+ CC
Sbjct: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCC 474
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 407 bits (1047), Expect = e-114
Identities = 234/474 (49%), Positives = 295/474 (62%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRD+AL+IS +EELP L+ PLF EAFSRRH + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL SLMK E +A+L+GL LLT + R RRWKLQVLDL+DV ENFW W A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A C P AM R+ +DCPR QPL VFID+CLK DE LF WV QR GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC KL +R LK + ++ I E+E++ ++ + YL +M+ L KLV S
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
E + VT+FT+ FL+L LQ L + ++F GHL+Q++ CL+ L L +
Sbjct: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
Query: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
T LLE DLK LS++PS+G LK L+LS L SL PL LLEK+AA+LE L L+ C
Sbjct: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
Query: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I SQ++AILP LS C +LTTF F N +S L++LL HT L+ L LE YPAP ES +
Sbjct: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
V F L AELM +R R+P+RI CP CG+ +LE+ CC
Sbjct: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCC 474
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 401 bits (1030), Expect = e-112
Identities = 230/476 (48%), Positives = 299/476 (62%), Gaps = 3/476 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLF EAFSRR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF A ++ +DCPR QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC KL P + +R LK++ ++ I E+E++ ++ + YL M+ L KLV S
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 R--CHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
Y S E + +VT+FT+ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 241 HMDVSRYVSP-EQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 ELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEG 358
+T LLE DLK LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LSCC +L TF F N +S+ L++LL HT L L +E YPAP ES
Sbjct: 360 CGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
++ + W F +RAELM +R+ R PKRI CP CG+ +LE CC
Sbjct: 420 YDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 397 bits (1019), Expect = e-110
Identities = 230/477 (48%), Positives = 298/477 (62%), Gaps = 4/477 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLF EAFSRR + L +MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF A ++ +DCPR QPL VF+++ LK DE L YL WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC KL P + +R LK++ ++ I E+E++ ++ + YL M+ L KLV S
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 241 R--CHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
Y S E + +VT+FT+ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 243 HMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 299 ELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEG 358
+T LLE DLK LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N + + L++LL HT L L +E YPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W F +RAELM +R+ R PKRI CP CG+ +LE CC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 397 bits (1019), Expect = e-110
Identities = 230/477 (48%), Positives = 298/477 (62%), Gaps = 4/477 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLF EAFSRR + L +MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF A ++ +DCPR QPL VF+++ LK DE L YL WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC KL P + +R LK++ ++ I E+E++ ++ + YL M+ L KLV S
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 241 R--CHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
Y S E + +VT+FT+ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 243 HMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 299 ELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEG 358
+T LLE DLK LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N + + L++LL HT L L +E YPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W F +RAELM +R+ R PKRI CP CG+ +LE CC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 397 bits (1019), Expect = e-110
Identities = 229/476 (48%), Positives = 298/476 (62%), Gaps = 3/476 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLF EAFSRR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF A ++ +DCPR QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC KL P + +R LK++ ++ I E+E++ ++ + YL M+ L KLV S
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 R--CHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
Y S E + +VT+FT+ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 241 HMDVSRYVSP-EQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 ELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEG 358
+T LLE DLK LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N +S+ L++LL HT L L +E YPAP ES
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
++ + W F +RAELM +R+ R PKRI CP CG+ +LE CC
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 396 bits (1018), Expect = e-110
Identities = 229/476 (48%), Positives = 297/476 (62%), Gaps = 3/476 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLF EAFSRR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF A + +DCPR QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC KL P + +R LK++ ++ I E+E++ ++ + YL M+ L KLV S
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 R--CHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
Y S E + +VT+FT+ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 241 HMDVSRYVSP-EQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 299 ELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEG 358
+T LLE DLK LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 359 CQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N +S+ L++LL HT L L +E YPAP ES
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 419 LNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
++ + W F +RAELM +R+ R PKRI CP CG+ +LE CC
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 390 bits (1002), Expect = e-108
Identities = 229/477 (48%), Positives = 294/477 (61%), Gaps = 4/477 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLEL G+SLLRDQAL++S +EELP L+ PLF EAFSRR + L +MVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF A + +DCPR E QPL VF+++ LK DE L L WV QRR L+HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC KL P + +R LK++ ++ I E+E++ ++ + YL ++ L KLV S
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
Query: 241 R--CHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
Y S E + +VT+FT+ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 278 HMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
Query: 299 ELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEG 358
+T LLE DLK LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
Query: 359 CQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N + + L++LL HT L L LE YPAP+ES
Sbjct: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
Query: 419 LNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W F +RAELM +R R PKRI CP G +LE CC
Sbjct: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 387 bits (994), Expect = e-107
Identities = 226/477 (47%), Positives = 294/477 (61%), Gaps = 4/477 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
MSI PPRLLELAG+SLLRDQAL++S +EELP L+ PLF EAFSRR + L +MVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LL RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF A ++ EDCPR QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
CC KL P + +R LK++ ++ I E+E++ ++ + YL M+ L KL+ S
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
Query: 241 R--CHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
Y S E + +VT+FT+ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 243 HMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
Query: 299 ELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEG 358
+T LLE DLK LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 359 CQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEES 418
C I SQ++AILP LS C +L TF F N + + L++LL HT L L +E YPAP ES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 419 LNSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W F +RAELM +R+ R PKRI CP CG+ +LE CC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 341 bits (875), Expect = 7e-94
Identities = 213/483 (44%), Positives = 291/483 (60%), Gaps = 15/483 (3%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLF AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLVSLMKT--LHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PL LMK LHLE KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPEA-----MSKRQTAEDCPRTGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE M+K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKT 233
++ ++ LCC KL + P++ ++ LK++ ++SI +LE+ T + K YL +M
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LCKLVFSRCH--HYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCL 291
L +L+ S H Y S + E + + +FTS FL L+ LQ L + + F G L+QL+R +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQY-IAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 QNPLENLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL 351
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 ETLVLEGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLET 411
+ LV + C I QL A+LP LS CSQLTT F N +SI AL+ LL+H GLS L+
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPEESLNSL-VRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELEL 470
YP P ES + ++ E L A L L E +P +++ PCP CG + E
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 471 HLC 473
LC
Sbjct: 501 ILC 503
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 341 bits (875), Expect = 7e-94
Identities = 213/483 (44%), Positives = 291/483 (60%), Gaps = 15/483 (3%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLF AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLVSLMKT--LHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PL LMK LHLE KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPEA-----MSKRQTAEDCPRTGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE M+K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKT 233
++ ++ LCC KL + P++ ++ LK++ ++SI +LE+ T + K YL +M
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LCKLVFSRCH--HYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCL 291
L +L+ S H Y S + E + + +FTS FL L+ LQ L + + F G L+QL+R +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQY-IAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 QNPLENLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL 351
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 ETLVLEGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLET 411
+ LV + C I QL A+LP LS CSQLTT F N +SI AL+ LL+H GLS L+
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPEESLNSL-VRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELEL 470
YP P ES + ++ E L A L L E +P +++ PCP CG + E
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 471 HLC 473
LC
Sbjct: 501 ILC 503
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 341 bits (875), Expect = 7e-94
Identities = 213/483 (44%), Positives = 291/483 (60%), Gaps = 15/483 (3%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLF AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLVSLMKT--LHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PL LMK LHLE KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPEA-----MSKRQTAEDCPRTGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE M+K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKT 233
++ ++ LCC KL + P++ ++ LK++ ++SI +LE+ T + K YL +M
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LCKLVFSRCH--HYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCL 291
L +L+ S H Y S + E + + +FTS FL L+ LQ L + + F G L+QL+R +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQY-IAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 QNPLENLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL 351
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 ETLVLEGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLET 411
+ LV + C I QL A+LP LS CSQLTT F N +SI AL+ LL+H GLS L+
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPEESLNSL-VRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELEL 470
YP P ES + ++ E L A L L E +P +++ PCP CG + E
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 471 HLC 473
LC
Sbjct: 501 ILC 503
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,999,751
Number of Sequences: 37866
Number of extensions: 859969
Number of successful extensions: 2755
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2637
Number of HSP's gapped (non-prelim): 65
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.