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Search of human proteins with 12738831
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12738831 PRAME family member 1 [Homo sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|12738831 PRAME family member 1 [Homo sapiens] 963 0.0
gi|66954681 PRAME family member 13 [Homo sapiens] 931 0.0
gi|12738834 PRAME family member 2 [Homo sapiens] 900 0.0
gi|153792140 PRAME family member 14 [Homo sapiens] 818 0.0
gi|194306635 PRAME family member 19 [Homo sapiens] 565 e-161
gi|154800493 PRAME family member 22 [Homo sapiens] 561 e-160
gi|153791443 PRAME family member 18 [Homo sapiens] 561 e-160
gi|194306638 PRAME family member 3 [Homo sapiens] 555 e-158
gi|194018546 PRAME family member 10 [Homo sapiens] 555 e-158
gi|157426839 PRAME family member 17 [Homo sapiens] 553 e-157
gi|113865933 PRAME family member 16 [Homo sapiens] 551 e-157
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ... 514 e-146
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ... 513 e-145
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 469 e-132
gi|124249372 PRAME family member 12 [Homo sapiens] 464 e-130
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 450 e-126
gi|59676587 PRAME family member 8 [Homo sapiens] 450 e-126
gi|59676593 PRAME family member 7 [Homo sapiens] 447 e-125
gi|153792112 PRAME family member 20 [Homo sapiens] 426 e-119
gi|153945800 PRAME family member 21 [Homo sapiens] 426 e-119
gi|148356236 PRAME family member 15 [Homo sapiens] 409 e-114
gi|61102721 PRAME family member 9 [Homo sapiens] 409 e-114
gi|61696142 PRAME family member 5 [Homo sapiens] 409 e-114
gi|58219004 PRAME family member 6 [Homo sapiens] 409 e-114
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 406 e-113
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 402 e-112
gi|59958373 PRAME family member 4 [Homo sapiens] 400 e-111
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 352 3e-97
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 352 3e-97
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 352 3e-97
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 963 bits (2489), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 931 bits (2405), Expect = 0.0
Identities = 458/474 (96%), Positives = 464/474 (97%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAF RRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPET SKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIK+LRKSLKIIYLNSIQ+LEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
RCHH SDNEL+GRLV KFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL
Sbjct: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL+TLILEGCQ
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILP LS CSQLTTFYFGRNCMS+ ALKDLLRHTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRV+WEIF LRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 900 bits (2326), Expect = 0.0
Identities = 444/474 (93%), Positives = 452/474 (95%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLF EAFSRRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPL SLMKTLHLE LKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPE SKRQTAEDCPR GEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIKYLRKSLKIIY+NSI ELEI N WP LIRKL CYLKEMK L KLVFS
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
RCHHYTSDNEL+G LV +F+SVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL
Sbjct: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
T G LLEED+KCLSQ+PSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL+TL+LEGCQ
Sbjct: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILP LS CSQLTTFYFG NCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN
Sbjct: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRVNWEIFTPLRAELMCTLRE RQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|153792140 PRAME family member 14 [Homo sapiens]
Length = 426
Score = 818 bits (2114), Expect = 0.0
Identities = 413/474 (87%), Positives = 418/474 (88%), Gaps = 48/474 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAF RRHFQTLTVMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSCFPET SKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSKLVNYLTPIK+LRKSLKIIYLNSIQ+LEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
R CLQNPLENLEL
Sbjct: 241 R------------------------------------------------CLQNPLENLEL 252
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL+TLILEGCQ
Sbjct: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
IHYSQLSAILP LS CSQLTTFYFGRNCMS+ ALKDLL HTSGLSKLSLETYPAPEESLN
Sbjct: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
SLVRV+WEIF LRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC
Sbjct: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 426
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 565 bits (1457), Expect = e-161
Identities = 297/473 (62%), Positives = 348/473 (73%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF+EAF+ R + L VMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE SKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I R L+ +Y +SIQ LEI NM WP ++ ++ YL +MKNLRKL S
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Y E QG+LVA+FSSVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
TYG L EED+KCL YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I YS+L ILPALSRCS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
+ RV E+ TPL+AELM LREVR+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 561 bits (1447), Expect = e-160
Identities = 293/473 (61%), Positives = 348/473 (73%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF+ R + L VMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL+LRDVDENFW W GA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE SKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Y ++ Q +LVA+FSSV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L L
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
TYG+L + D+KCL +YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I S+L ILPALS CS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
RV E+ TPL+AELM LREVR+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 561 bits (1447), Expect = e-160
Identities = 296/473 (62%), Positives = 347/473 (73%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF+EAF+ R + L VMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE SKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I R L+ +Y +SIQ LEI NM WP ++ ++ YL +MKNLRKL S
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Y E QG+LVA+FSSVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
TYG L EED+KCL YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I S+L ILPALSRCS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
+ RV E+ TPL+AELM LREVR+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 555 bits (1431), Expect = e-158
Identities = 292/473 (61%), Positives = 347/473 (73%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF+ R + L VMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE SKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Y ++ Q +LVA+FSSV LRLE+LQ+L ++ + FF GHL+QLIRCL++PLE L L
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
TYG+L + D+KCL +YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I S+L ILPALS CS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
RV E+ TPL+AELM LREVR+PKRIF GP CP CG+SP+E+LE + C
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 555 bits (1430), Expect = e-158
Identities = 288/473 (60%), Positives = 340/473 (71%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAFS R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKTLHLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE SKRQT EDCPRMGEHQPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSK+ NY P R L+ IY +SIQELE+ K YL +M NLR+L +
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
+ +Q + S FL L + Q+L IK I+ HLE L+R L+NPL
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
+ YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+AA+LKTL+L+ C+
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I QL +LPALS CSQLTTF F N S++ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
VNWEI TP+RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 553 bits (1426), Expect = e-157
Identities = 289/477 (60%), Positives = 345/477 (72%), Gaps = 8/477 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEA S RHF+ L +MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSC PE SKRQT ED PR GEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+ NY P R LK +Y +SIQELEI+ K YL +M NLRKL +
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 RCHHYTSDNEL----QGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
+ D+EL Q + V FL L + Q+L I+ I+ HLE L+RCL+NPL
Sbjct: 241 ----FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
Query: 297 NLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLIL 356
+ YL ++DM+CLSQYPSL LK L+L ++L++ +LEPLGALLEK+AA+L+ L L
Sbjct: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
Query: 357 EGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPE 416
+ CQI SQL +LPALSRCSQLTTFYF N S +ALKDLL HT GLSKL LE YPAP
Sbjct: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
Query: 417 ESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
E L++ VNWEI P+RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 551 bits (1421), Expect = e-157
Identities = 288/477 (60%), Positives = 344/477 (72%), Gaps = 8/477 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS+Q+P RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEA S RHF+ L +MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L+GL LL QK RPRRWKLQVLDLRDVD NFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALSC PE KRQT ED PR GEHQPLKVFID+C KE DECL YL +W++ RRGLVHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+ NY P R LK +Y +SIQELEI+ K YL +M NLRKL +
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 RCHHYTSDNEL----QGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLE 296
+ D+EL Q + V FL L + Q+L I+ I+ HLE L+RCL+NPL
Sbjct: 241 ----FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLG 296
Query: 297 NLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLIL 356
+ YL ++DM+CLSQYPSL LK L+L ++L++ +LEPLGALLEK+AA+L+ L L
Sbjct: 297 TFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTL 356
Query: 357 EGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPE 416
+ CQI SQL +LPALSRCSQLTTFYF N S +ALKDLL HT GLSKL LE YPAP
Sbjct: 357 KDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPL 416
Query: 417 ESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
E L++ VNWEI P+RAELMCTLREVRQPKRIF GP PCPSCGS PSE+++ HLC
Sbjct: 417 ECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 514 bits (1323), Expect = e-146
Identities = 273/473 (57%), Positives = 318/473 (67%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAFS R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE SKRQT EDCPRMGE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSK+ NY P R L+ IY +SIQELE+ K YL +M NLR+L F
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
R L+NPL
Sbjct: 241 RY------------------------------------------------LKNPLGAFIF 252
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
+ YL + DM+CLSQYPSL LK L L ++L++ +LEPLG LLEK+AA+LKTL+L+ C+
Sbjct: 253 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I QL +LPALS CSQLTTF F N S++ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
VNWEI TP+RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 513 bits (1321), Expect = e-145
Identities = 273/473 (57%), Positives = 317/473 (67%), Gaps = 48/473 (10%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLLR+Q L+I ++ELPR ++ +FMEAFS R F+ L +MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMKT HLETL+A+L GL L+ QK RPRRWKLQVLDLRDVDENFW W GA
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE SKRQT EDCPRMGE QPLKVFID+CLKE DECL YLF W++ RRGLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CCSK+ NY P R L+ IY +SIQELE+ K YL +M NLR+L F
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
R L+NPL
Sbjct: 241 RY------------------------------------------------LKNPLGAFIF 252
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
+ YL + DM+CLSQYPSL LK L L ++L++ LEPLG LLEK+AA+LKTL+L+ C+
Sbjct: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I QL +LPALS CSQLTTF F N S++ALKDLLRHT GLSKL LE YPAP ESL+
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
VNWEI TP+RAELM TLREVRQPKRIF GP PCP+CGS PSE+++ HLC
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 469 bits (1208), Expect = e-132
Identities = 258/475 (54%), Positives = 321/475 (67%), Gaps = 2/475 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF+ R + L VMVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F CLPLGSLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
LSC PE SKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC+K+VNY I R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
Query: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Y ++ Q + +A F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L +
Sbjct: 241 DGCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
Query: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+ C
Sbjct: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
Query: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
I SQ++AILPALSRC +L TF F N +S+ L++LL HT L L LE YPAP ES
Sbjct: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
Query: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
+ + W FT +RAELM +R++R PKRI G CP CG+ +LE CC
Sbjct: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 464 bits (1193), Expect = e-130
Identities = 258/480 (53%), Positives = 327/480 (68%), Gaps = 8/480 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MS+QAPPRLLELA QSLLRD+AL+I +EELPR L+ PLFMEAF+RR +TLT MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FTCLPLGSLMK+ +LE +A+LEGL LL QK RPRRWKLQVLDLR+VDENFW W GA
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
ALS PE SKR+TA +CPR G QPL V +D+C K DECL + +W QR+GL+H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
CC +L + I + + L + L+ IQE+E+ ++ + YL +M+NLRKLV
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
Query: 241 RCHHYTS-DNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
H + + + V +F+S FL+L++ Q L + ++F GHL+QL+RCLQ PLE +
Sbjct: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
Query: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGC 359
+T L E D+K LS PS+ LK L+L + L S EPL LLE+ A+L+TL LE C
Sbjct: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
Query: 360 QIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESL 419
I SQLSAILPALSRCSQL+TF F N +S+ AL++LLRHT GLSKLSLE YPAP ES
Sbjct: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 420 NSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELE-----LHLCC 474
++ + W F+ L AELM TLR++RQPK I PCP CG S +LE L+ CC
Sbjct: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 450 bits (1157), Expect = e-126
Identities = 258/478 (53%), Positives = 327/478 (68%), Gaps = 11/478 (2%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAFSRR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPE S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVF- 239
CC +L + PI + + L ++ L+ IQE+E+ + K YL +M+NLRKLV
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 240 ----SRCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPL 295
S C DN+ G+ +A+F+S FL+L++ Q L + ++F GHL+QL+RCLQ L
Sbjct: 239 NIRASAC--IPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294
Query: 296 ENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLI 355
E + +T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL
Sbjct: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354
Query: 356 LEGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAP 415
LE C I SQLSAILP LSRCSQL+TF F N +S+ AL++LLRHT GLSKLSLE YPAP
Sbjct: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414
Query: 416 EESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
ES ++ + W F L AELM TLR++RQPK I PCP CG S +LE C
Sbjct: 415 LESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 450 bits (1157), Expect = e-126
Identities = 258/478 (53%), Positives = 327/478 (68%), Gaps = 11/478 (2%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAFSRR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPE S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVF- 239
CC +L + PI + + L ++ L+ IQE+E+ + K YL +M+NLRKLV
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 240 ----SRCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPL 295
S C DN+ G+ +A+F+S FL+L++ Q L + ++F GHL+QL+RCLQ L
Sbjct: 239 NIRASAC--IPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294
Query: 296 ENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLI 355
E + +T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL
Sbjct: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354
Query: 356 LEGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAP 415
LE C I SQLSAILP LSRCSQL+TF F N +S+ AL++LLRHT GLSKLSLE YPAP
Sbjct: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414
Query: 416 EESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
ES ++ + W F L AELM TLR++RQPK I PCP CG S +LE C
Sbjct: 415 LESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 447 bits (1150), Expect = e-125
Identities = 257/478 (53%), Positives = 326/478 (68%), Gaps = 11/478 (2%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+APPRLLELA Q LLRDQAL+IS MEELPR L+ LFMEAFSRR +TL MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
FT LPLGSLMK+ HLE+LK++LEG+ +LLTQ+ RPR+ KLQVLDLR+VDENF + GA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A FPE S++QTA++CP G QP VFID+CLK DECL +L +W QR+GL+H+
Sbjct: 121 A--SFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVF- 239
CC +L + PI + + L ++ L+ IQE+E+ + K YL +M+NLRKLV
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 240 ----SRCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPL 295
S C DN+ G+ +A+F+S FL+L++ Q L + ++F GHL+QL+RCLQ L
Sbjct: 239 NIRASAC--IPPDNK--GQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294
Query: 296 ENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLI 355
E + +T L E D+K LS PS+ LK L+L V L S EPL LLE++ A+L+TL
Sbjct: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354
Query: 356 LEGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAP 415
LE C I SQLSAILP LSRCSQL+TF F N +S+ AL++LLRHT GLSKLSLE YPAP
Sbjct: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414
Query: 416 EESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
ES ++ + W F L AELM T R++RQPK I PCP CG S +LE C
Sbjct: 415 LESYDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHC 472
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 426 bits (1095), Expect = e-119
Identities = 241/475 (50%), Positives = 304/475 (64%), Gaps = 2/475 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRD+AL+IS +EELP L+ PLFMEAFSRRH + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMK ET +A+L+GL LLT + R RRWKLQVLDL+DV ENFW W A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A C P R+ +DCPRM QPL VFID+CLK DE LF WV QR GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL +R LK + L+ IQE+E+ N +W ++ + YL +M+NLRKLV
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 240 SRCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
S E + V +F++ FL+L LQ L + ++F GHL+Q++ CL+ L L
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGC 359
+T LLE D+K LS+YPS+G LK L+LS L SL PL LLEK+AA+L+ L L+ C
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 360 QIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESL 419
I SQ++AILPALSRC +LTTF F N +S L++LL HT L+ L LE YPAP ES
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 420 NSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
+ V F L AELM +R +R+P+RI CP CG+ +LE+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCC 474
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 426 bits (1095), Expect = e-119
Identities = 241/475 (50%), Positives = 304/475 (64%), Gaps = 2/475 (0%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRD+AL+IS +EELP L+ PLFMEAFSRRH + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPLGSLMK ET +A+L+GL LLT + R RRWKLQVLDL+DV ENFW W A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A C P R+ +DCPRM QPL VFID+CLK DE LF WV QR GLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL +R LK + L+ IQE+E+ N +W ++ + YL +M+NLRKLV
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 240 SRCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
S E + V +F++ FL+L LQ L + ++F GHL+Q++ CL+ L L
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGC 359
+T LLE D+K LS+YPS+G LK L+LS L SL PL LLEK+AA+L+ L L+ C
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 360 QIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESL 419
I SQ++AILPALSRC +LTTF F N +S L++LL HT L+ L LE YPAP ES
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 420 NSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
+ V F L AELM +R +R+P+RI CP CG+ +LE+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCC 474
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 409 bits (1052), Expect = e-114
Identities = 234/478 (48%), Positives = 305/478 (63%), Gaps = 6/478 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAFSRR + L +MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L YL WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P + +R LK++ L+ IQE+E+ N W ++ + YL M+NL+KLV
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
Query: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
S Y S E + +V +F++ FL+L LQ L + ++F GHL+QL+ CL+ L+
Sbjct: 242 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
Query: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357
L +T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417
C I SQ++AILPALSRC +L TF F N + + L++LL HT L L +E YPAP E
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
S + + W F +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 409 bits (1052), Expect = e-114
Identities = 234/478 (48%), Positives = 305/478 (63%), Gaps = 6/478 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAFSRR + L +MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L YL WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P + +R LK++ L+ IQE+E+ N W ++ + YL M+NL+KLV
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
Query: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
S Y S E + +V +F++ FL+L LQ L + ++F GHL+QL+ CL+ L+
Sbjct: 242 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
Query: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357
L +T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417
C I SQ++AILPALSRC +L TF F N + + L++LL HT L L +E YPAP E
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
S + + W F +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 409 bits (1052), Expect = e-114
Identities = 233/477 (48%), Positives = 305/477 (63%), Gaps = 5/477 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAFSRR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P + +R LK++ L+ IQE+E+ N W ++ + YL M+NL+KLV
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
S Y S E + +V +F++ FL+L LQ L + ++F GHL+QL+ CL+ L+
Sbjct: 240 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
Query: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357
L +T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
Query: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417
C I SQ++AILPALSRC +L TF F N +S+ L++LL HT L L +E YPAP E
Sbjct: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
Query: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
S ++ + W F +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 409 bits (1051), Expect = e-114
Identities = 233/477 (48%), Positives = 304/477 (63%), Gaps = 5/477 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAFSRR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF + +DCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P + +R LK++ L+ IQE+E+ N W ++ + YL M+NL+KLV
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
S Y S E + +V +F++ FL+L LQ L + ++F GHL+QL+ CL+ L+
Sbjct: 240 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
Query: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357
L +T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
Query: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417
C I SQ++AILPALSRC +L TF F N +S+ L++LL HT L L +E YPAP E
Sbjct: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
Query: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
S ++ + W F +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 406 bits (1043), Expect = e-113
Identities = 232/477 (48%), Positives = 304/477 (63%), Gaps = 5/477 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAFSRR + L +MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ PRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ +DCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P + +R LK++ L+ IQE+E+ N W ++ + YL M+NL+KLV
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
S Y S E + +V +F++ FL+L LQ L + ++F GHL+QL+ CL+ L+
Sbjct: 240 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
Query: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357
L +T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
Query: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417
C I SQ++AILPALS C +L TF F N +S+ L++LL HT L L +E YPAP E
Sbjct: 359 DCGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
Query: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
S ++ + W F +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 419 SYDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 402 bits (1034), Expect = e-112
Identities = 233/478 (48%), Positives = 301/478 (62%), Gaps = 6/478 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI+ PPRLLEL G+SLLRDQAL++S +EELP L+ PLFMEAFSRR + L +MVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF + +DCPRM E QPL VF+++ LK DE L L WV QRR L+HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSW-PRLIRKLRCYLKEMKNLRKLVF 239
CC KL P + +R LK++ L+ IQE+E+ N W ++ + YL ++NL+KLV
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276
Query: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
S Y S E + +V +F++ FL+L LQ L + ++F GHL+QL+ CL+ L+
Sbjct: 277 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335
Query: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357
L +T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+
Sbjct: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395
Query: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417
C I SQ++AILPALSRC +L TF F N + + L++LL HT L L LE YPAP+E
Sbjct: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455
Query: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
S + + W F +RAELM +R +R PKRI CP G +LE CC
Sbjct: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 400 bits (1027), Expect = e-111
Identities = 230/478 (48%), Positives = 301/478 (62%), Gaps = 6/478 (1%)
Query: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
MSI PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAFSRR + L +MVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
F LPL L+K LE +A+L+GL LL RPRRWKLQVLDL+DV ENFW W A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
A CF ++ EDCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
CC KL P + +R LK++ L+ IQE+E+ N W ++ + YL M+NL+KL+
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241
Query: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
S Y S E + +V +F++ FL+L LQ L + ++F GHL+QL+ CL+ L+
Sbjct: 242 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
Query: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357
L +T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417
C I SQ++AILPALSRC +L TF F N + + L++LL HT L L +E YPAP E
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
S + + W F +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 352 bits (904), Expect = 3e-97
Identities = 216/483 (44%), Positives = 298/483 (61%), Gaps = 15/483 (3%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKT--LHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PLG LMK LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPETTS-----KRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE + K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKN 233
++ ++ LCC KL + P++ ++ LK++ L+SI++LE+ + K YL +M N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLVFSRCH--HYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCL 291
LR+L+ S H Y S E + + +A+F+S FL L+ LQ L + + F G L+QL+R +
Sbjct: 262 LRRLLLSHIHASSYISP-EKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 QNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL 351
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 KTLILEGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLET 411
+ L+ + C I QL A+LP+LS CSQLTT F N +SI AL+ LL+H GLS L+
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPEESLNSL-VRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL 470
YP P ES + ++ E L A L L E+ +P +++ PCP CG + E
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 471 HLC 473
LC
Sbjct: 501 ILC 503
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 352 bits (904), Expect = 3e-97
Identities = 216/483 (44%), Positives = 298/483 (61%), Gaps = 15/483 (3%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKT--LHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PLG LMK LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPETTS-----KRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE + K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKN 233
++ ++ LCC KL + P++ ++ LK++ L+SI++LE+ + K YL +M N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLVFSRCH--HYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCL 291
LR+L+ S H Y S E + + +A+F+S FL L+ LQ L + + F G L+QL+R +
Sbjct: 262 LRRLLLSHIHASSYISP-EKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 QNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL 351
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 KTLILEGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLET 411
+ L+ + C I QL A+LP+LS CSQLTT F N +SI AL+ LL+H GLS L+
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPEESLNSL-VRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL 470
YP P ES + ++ E L A L L E+ +P +++ PCP CG + E
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 471 HLC 473
LC
Sbjct: 501 ILC 503
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 352 bits (904), Expect = 3e-97
Identities = 216/483 (44%), Positives = 298/483 (61%), Gaps = 15/483 (3%)
Query: 5 APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWPFTCL 64
+P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF RH QTL MVQAWPFTCL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKT--LHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121
PLG LMK LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR + ++FW W G A
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 -LSCFPETTS-----KRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173
L FPE + K++ + E P++V +D+ LKE DE YL + V +
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGLVHLCCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKN 233
++ ++ LCC KL + P++ ++ LK++ L+SI++LE+ + K YL +M N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLVFSRCH--HYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCL 291
LR+L+ S H Y S E + + +A+F+S FL L+ LQ L + + F G L+QL+R +
Sbjct: 262 LRRLLLSHIHASSYISP-EKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 QNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL 351
NPLE L +T L E D+ LSQ PS+ L L+LS V+L +S EPL ALLE+ +A+L
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 KTLILEGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLET 411
+ L+ + C I QL A+LP+LS CSQLTT F N +SI AL+ LL+H GLS L+
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPEESLNSL-VRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL 470
YP P ES + ++ E L A L L E+ +P +++ PCP CG + E
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
Query: 471 HLC 473
LC
Sbjct: 501 ILC 503
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,376,670
Number of Sequences: 37866
Number of extensions: 815509
Number of successful extensions: 2775
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2648
Number of HSP's gapped (non-prelim): 64
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.