Search of human proteins with 12707577

Search of human proteins with 12707577

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
         (245 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi...   486   e-138
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]   397   e-111
gi|7706659 paired related homeobox 2 [Homo sapiens]                   260   7e-70
gi|189083681 paired box gene 6 isoform a [Homo sapiens]               108   4e-24
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                 108   4e-24
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                 108   4e-24
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...   105   4e-23
gi|46249382 paired-like homeobox 2a [Homo sapiens]                    104   8e-23
gi|12707580 paired-like homeobox 2b [Homo sapiens]                    103   1e-22
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                103   2e-22
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                 103   2e-22
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                 103   2e-22
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                 103   2e-22
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                 103   2e-22
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                  103   2e-22
gi|24497589 aristaless related homeobox [Homo sapiens]                103   2e-22
gi|122937484 dorsal root ganglia homeobox [Homo sapiens]              102   2e-22
gi|55743092 aristaless-like homeobox 4 [Homo sapiens]                 102   3e-22
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap...   100   1e-21
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                       99   3e-21
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                       99   3e-21
gi|207029223 paired box 7 isoform 3 [Homo sapiens]                     99   3e-21
gi|113204604 aristaless-like homeobox 3 [Homo sapiens]                 99   3e-21
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]          96   2e-20
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]      96   3e-20
gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens]         95   5e-20
gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]         95   5e-20
gi|24234708 paired-like homeodomain transcription factor 2 isofo...    94   1e-19
gi|87044888 short stature homeobox 2 isoform b [Homo sapiens]          94   1e-19
gi|21361183 paired-like homeodomain transcription factor 2 isofo...    92   4e-19

>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
           sapiens]
          Length = 245

 Score =  486 bits (1251), Expect = e-138
 Identities = 245/245 (100%), Positives = 245/245 (100%)

Query: 1   MTSSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADENVGEA 60
           MTSSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADENVGEA
Sbjct: 1   MTSSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADENVGEA 60

Query: 61  GRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPD 120
           GRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPD
Sbjct: 61  GRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPD 120

Query: 121 AFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIV 180
           AFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIV
Sbjct: 121 AFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIV 180

Query: 181 PRPAPRPTDYLSWGTASPYSAMATYSATCANNSPAQGINMANSIANLRLKAKEYSLQRNQ 240
           PRPAPRPTDYLSWGTASPYSAMATYSATCANNSPAQGINMANSIANLRLKAKEYSLQRNQ
Sbjct: 181 PRPAPRPTDYLSWGTASPYSAMATYSATCANNSPAQGINMANSIANLRLKAKEYSLQRNQ 240

Query: 241 VPTVN 245
           VPTVN
Sbjct: 241 VPTVN 245


>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
          Length = 217

 Score =  397 bits (1021), Expect = e-111
 Identities = 199/199 (100%), Positives = 199/199 (100%)

Query: 1   MTSSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADENVGEA 60
           MTSSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADENVGEA
Sbjct: 1   MTSSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADENVGEA 60

Query: 61  GRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPD 120
           GRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPD
Sbjct: 61  GRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPD 120

Query: 121 AFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIV 180
           AFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIV
Sbjct: 121 AFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIV 180

Query: 181 PRPAPRPTDYLSWGTASPY 199
           PRPAPRPTDYLSWGTASPY
Sbjct: 181 PRPAPRPTDYLSWGTASPY 199


>gi|7706659 paired related homeobox 2 [Homo sapiens]
          Length = 253

 Score =  260 bits (665), Expect = 7e-70
 Identities = 154/244 (63%), Positives = 179/244 (73%), Gaps = 25/244 (10%)

Query: 13  PALGGRLDSPGNLDTLQAKKNFSVSHLLDLEE---AGDMVA---AQADENVGEAGRSLLE 66
           PALG     PG  D  QA+KNFSVSHLLDLEE   AG + A   A+A+   G A     E
Sbjct: 24  PALG-----PG--DCAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAREGAAR----E 72

Query: 67  SPGLTSGSDTPQQDND----QLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAF 122
             G +SGS+   QD +       S  K+K+KQRRNRTTFNSSQLQALERVFERTHYPDAF
Sbjct: 73  PSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAF 132

Query: 123 VREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVPR 182
           VRE+LARRVNL+EARVQVWFQNRRAKFRRNERAMLA+++ASLLKSYS +  A+EQP+ PR
Sbjct: 133 VREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQE-AAIEQPVAPR 191

Query: 183 PAPRPTDYLSWGTASPYSAMATYSATCANNSPA-QGINMANSIANLRLKAKEYSLQRNQV 241
           P     DYLSW  +SPYS +  YS    ++ PA  G+NMANSIA+LRLKAKE+SL  +QV
Sbjct: 192 PTALSPDYLSWTASSPYSTVPPYSP--GSSGPATPGVNMANSIASLRLKAKEFSLHHSQV 249

Query: 242 PTVN 245
           PTVN
Sbjct: 250 PTVN 253


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  108 bits (270), Expect = 4e-24
 Identities = 66/159 (41%), Positives = 91/159 (57%), Gaps = 14/159 (8%)

Query: 71  TSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARR 130
           T+   +  +D+D+     + KRK +RNRT+F   Q++ALE+ FERTHYPD F RE LA +
Sbjct: 187 TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAK 246

Query: 131 VNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSY----SGDVTAVEQPIVPRPAPR 186
           ++L EAR+QVWF NRRAK+RR E+     + AS   S+    S   T+V QPI P+P   
Sbjct: 247 IDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPI-PQPTTP 305

Query: 187 PTDYLS--------WGTASPYSAMATY-SATCANNSPAQ 216
            + + S            + YSA+    S T ANN P Q
Sbjct: 306 VSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQ 344


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score =  108 bits (270), Expect = 4e-24
 Identities = 66/159 (41%), Positives = 91/159 (57%), Gaps = 14/159 (8%)

Query: 71  TSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARR 130
           T+   +  +D+D+     + KRK +RNRT+F   Q++ALE+ FERTHYPD F RE LA +
Sbjct: 201 TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAK 260

Query: 131 VNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSY----SGDVTAVEQPIVPRPAPR 186
           ++L EAR+QVWF NRRAK+RR E+     + AS   S+    S   T+V QPI P+P   
Sbjct: 261 IDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPI-PQPTTP 319

Query: 187 PTDYLS--------WGTASPYSAMATY-SATCANNSPAQ 216
            + + S            + YSA+    S T ANN P Q
Sbjct: 320 VSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQ 358


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score =  108 bits (270), Expect = 4e-24
 Identities = 66/159 (41%), Positives = 91/159 (57%), Gaps = 14/159 (8%)

Query: 71  TSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARR 130
           T+   +  +D+D+     + KRK +RNRT+F   Q++ALE+ FERTHYPD F RE LA +
Sbjct: 187 TNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAK 246

Query: 131 VNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSY----SGDVTAVEQPIVPRPAPR 186
           ++L EAR+QVWF NRRAK+RR E+     + AS   S+    S   T+V QPI P+P   
Sbjct: 247 IDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPI-PQPTTP 305

Query: 187 PTDYLS--------WGTASPYSAMATY-SATCANNSPAQ 216
            + + S            + YSA+    S T ANN P Q
Sbjct: 306 VSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQ 344


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score =  105 bits (262), Expect = 4e-23
 Identities = 52/88 (59%), Positives = 64/88 (72%), Gaps = 3/88 (3%)

Query: 67  SPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVRED 126
           SPGL  G   P     +L+ EE+ K+K RRNRTTF + QL  LER FE++HYPD + RE+
Sbjct: 112 SPGLPVG---PATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREE 168

Query: 127 LARRVNLTEARVQVWFQNRRAKFRRNER 154
           LA +VNL E RVQVWFQNRRAK+RR E+
Sbjct: 169 LAGKVNLPEVRVQVWFQNRRAKWRRQEK 196


>gi|46249382 paired-like homeobox 2a [Homo sapiens]
          Length = 284

 Score =  104 bits (259), Expect = 8e-23
 Identities = 51/82 (62%), Positives = 62/82 (75%)

Query: 90  KKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKF 149
           +KRKQRR RTTF S+QL+ LERVF  THYPD + RE+LA +++LTEARVQVWFQNRRAKF
Sbjct: 86  EKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKF 145

Query: 150 RRNERAMLANKNASLLKSYSGD 171
           R+ ERA  A   A    +  G+
Sbjct: 146 RKQERAASAKGAAGAAGAKKGE 167


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score =  103 bits (257), Expect = 1e-22
 Identities = 49/69 (71%), Positives = 58/69 (84%)

Query: 90  KKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKF 149
           +KRKQRR RTTF S+QL+ LERVF  THYPD + RE+LA +++LTEARVQVWFQNRRAKF
Sbjct: 94  EKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKF 153

Query: 150 RRNERAMLA 158
           R+ ERA  A
Sbjct: 154 RKQERAAAA 162


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score =  103 bits (256), Expect = 2e-22
 Identities = 57/116 (49%), Positives = 76/116 (65%), Gaps = 5/116 (4%)

Query: 43  EEAGDMVAAQADENVGEAGRSLLESPGLTSGSDTPQQDN-DQLNSEEKK--KRKQRRNRT 99
           EE  D+   +A+E+  +A  S+     L+  +  PQ D    ++SE     KRKQRR+RT
Sbjct: 166 EEEADLERKEAEESEKKAKHSI--DGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRT 223

Query: 100 TFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA 155
           TF + QL+ LER FERTHYPD + RE+LA+R  LTEARVQVWF NRRA++R+   A
Sbjct: 224 TFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGA 279


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score =  103 bits (256), Expect = 2e-22
 Identities = 57/116 (49%), Positives = 76/116 (65%), Gaps = 5/116 (4%)

Query: 43  EEAGDMVAAQADENVGEAGRSLLESPGLTSGSDTPQQDN-DQLNSEEKK--KRKQRRNRT 99
           EE  D+   +A+E+  +A  S+     L+  +  PQ D    ++SE     KRKQRR+RT
Sbjct: 167 EEEADLERKEAEESEKKAKHSI--DGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRT 224

Query: 100 TFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA 155
           TF + QL+ LER FERTHYPD + RE+LA+R  LTEARVQVWF NRRA++R+   A
Sbjct: 225 TFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGA 280


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score =  103 bits (256), Expect = 2e-22
 Identities = 57/116 (49%), Positives = 76/116 (65%), Gaps = 5/116 (4%)

Query: 43  EEAGDMVAAQADENVGEAGRSLLESPGLTSGSDTPQQDN-DQLNSEEKK--KRKQRRNRT 99
           EE  D+   +A+E+  +A  S+     L+  +  PQ D    ++SE     KRKQRR+RT
Sbjct: 167 EEEADLERKEAEESEKKAKHSI--DGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRT 224

Query: 100 TFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA 155
           TF + QL+ LER FERTHYPD + RE+LA+R  LTEARVQVWF NRRA++R+   A
Sbjct: 225 TFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGA 280


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score =  103 bits (256), Expect = 2e-22
 Identities = 57/116 (49%), Positives = 76/116 (65%), Gaps = 5/116 (4%)

Query: 43  EEAGDMVAAQADENVGEAGRSLLESPGLTSGSDTPQQDN-DQLNSEEKK--KRKQRRNRT 99
           EE  D+   +A+E+  +A  S+     L+  +  PQ D    ++SE     KRKQRR+RT
Sbjct: 167 EEEADLERKEAEESEKKAKHSI--DGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRT 224

Query: 100 TFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA 155
           TF + QL+ LER FERTHYPD + RE+LA+R  LTEARVQVWF NRRA++R+   A
Sbjct: 225 TFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGA 280


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score =  103 bits (256), Expect = 2e-22
 Identities = 57/116 (49%), Positives = 76/116 (65%), Gaps = 5/116 (4%)

Query: 43  EEAGDMVAAQADENVGEAGRSLLESPGLTSGSDTPQQDN-DQLNSEEKK--KRKQRRNRT 99
           EE  D+   +A+E+  +A  S+     L+  +  PQ D    ++SE     KRKQRR+RT
Sbjct: 167 EEEADLERKEAEESEKKAKHSI--DGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRT 224

Query: 100 TFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA 155
           TF + QL+ LER FERTHYPD + RE+LA+R  LTEARVQVWF NRRA++R+   A
Sbjct: 225 TFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGA 280


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score =  103 bits (256), Expect = 2e-22
 Identities = 57/116 (49%), Positives = 76/116 (65%), Gaps = 5/116 (4%)

Query: 43  EEAGDMVAAQADENVGEAGRSLLESPGLTSGSDTPQQDN-DQLNSEEKK--KRKQRRNRT 99
           EE  D+   +A+E+  +A  S+     L+  +  PQ D    ++SE     KRKQRR+RT
Sbjct: 167 EEEADLERKEAEESEKKAKHSI--DGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRT 224

Query: 100 TFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA 155
           TF + QL+ LER FERTHYPD + RE+LA+R  LTEARVQVWF NRRA++R+   A
Sbjct: 225 TFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGA 280


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score =  103 bits (256), Expect = 2e-22
 Identities = 54/95 (56%), Positives = 68/95 (71%), Gaps = 9/95 (9%)

Query: 61  GRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPD 120
           G+   +S  L++GSD+          E   KRKQRR RTTF S QL+ LER F++THYPD
Sbjct: 304 GKDGEDSVCLSAGSDS---------EEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPD 354

Query: 121 AFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA 155
            F RE+LA R++LTEARVQVWFQNRRAK+R+ E+A
Sbjct: 355 VFTREELAMRLDLTEARVQVWFQNRRAKWRKREKA 389



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 17/39 (43%), Positives = 23/39 (58%)

Query: 203 ATYSATCANNSPAQGINMANSIANLRLKAKEYSLQRNQV 241
           A  S   A+ + A     A+SIA LRLKAKE++ Q  Q+
Sbjct: 511 AVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQL 549


>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
          Length = 268

 Score =  102 bits (255), Expect = 2e-22
 Identities = 47/64 (73%), Positives = 55/64 (85%)

Query: 91  KRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFR 150
           +RKQRRNRTTF   QL+ALE VF +THYPD F RE+LA ++NLTEARVQVWFQNRRAK+R
Sbjct: 35  RRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWR 94

Query: 151 RNER 154
           + ER
Sbjct: 95  KTER 98


>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
          Length = 411

 Score =  102 bits (254), Expect = 3e-22
 Identities = 80/229 (34%), Positives = 104/229 (45%), Gaps = 54/229 (23%)

Query: 56  NVGEAGRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFER 115
           +V EAG   ++ P   + SD P          E  K K+RRNRTTF S QL+ LE+VF++
Sbjct: 181 SVKEAG---VKGPQDRASSDLPSPLEKA--DSESNKGKKRRNRTTFTSYQLEELEKVFQK 235

Query: 116 THYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNER--------------------- 154
           THYPD + RE LA R +LTEARVQVWFQNRRAK+R+ ER                     
Sbjct: 236 THYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLT 295

Query: 155 -----AMLANKNASLLKSYSGDVTAVEQPIVPRP-------------APRPTDYLSWGTA 196
                A + N +       +  V A   P  P P             A   TD+LS   A
Sbjct: 296 RAENYAQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVSGA 355

Query: 197 SPYSAMATYSATCANNSPAQGIN----------MANSIANLRLKAKEYS 235
             +       +     S + G+N            +SIA LR+KAKE+S
Sbjct: 356 GSHVGQTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHS 404


>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
           sapiens]
          Length = 184

 Score =  100 bits (249), Expect = 1e-21
 Identities = 56/102 (54%), Positives = 65/102 (63%), Gaps = 11/102 (10%)

Query: 87  EEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRR 146
           EE  K+K RRNRTTF + QL  LER FE +HYPD + RE+LA +V+L E RVQVWFQNRR
Sbjct: 20  EEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRR 79

Query: 147 AKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVPR-PAPRP 187
           AK+RR ER          L+S SG V A   P  P  P  RP
Sbjct: 80  AKWRRQER----------LESGSGAVAAPRLPEAPALPFARP 111


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 76/216 (35%), Positives = 105/216 (48%), Gaps = 44/216 (20%)

Query: 43  EEAGDMVAAQADENV-GEAGRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTF 101
           E+ G+  A  + + + G+ G  L E   + S  D P             KRKQRR+RTTF
Sbjct: 177 EDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPL------------KRKQRRSRTTF 224

Query: 102 NSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA-MLANK 160
            + QL+ LE+ FERTHYPD + RE+LA+R  LTEARVQVWF NRRA++R+   A  LA  
Sbjct: 225 TAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAF 284

Query: 161 NASL----------------LKSYSGDVTAVEQ---PIVPRPAPRPTDYLSWG------- 194
           N  L                L   +   T + Q     V RP P P   +  G       
Sbjct: 285 NHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAA 344

Query: 195 ---TASPYSAMATYSA-TCANNSPAQGINMANSIAN 226
              T+S Y A  ++S+ + +  +PA   N  N ++N
Sbjct: 345 AADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSN 380


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 76/216 (35%), Positives = 105/216 (48%), Gaps = 44/216 (20%)

Query: 43  EEAGDMVAAQADENV-GEAGRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTF 101
           E+ G+  A  + + + G+ G  L E   + S  D P             KRKQRR+RTTF
Sbjct: 175 EDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPL------------KRKQRRSRTTF 222

Query: 102 NSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA-MLANK 160
            + QL+ LE+ FERTHYPD + RE+LA+R  LTEARVQVWF NRRA++R+   A  LA  
Sbjct: 223 TAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAF 282

Query: 161 NASL----------------LKSYSGDVTAVEQ---PIVPRPAPRPTDYLSWG------- 194
           N  L                L   +   T + Q     V RP P P   +  G       
Sbjct: 283 NHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAA 342

Query: 195 ---TASPYSAMATYSA-TCANNSPAQGINMANSIAN 226
              T+S Y A  ++S+ + +  +PA   N  N ++N
Sbjct: 343 AADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSN 378


>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 76/216 (35%), Positives = 105/216 (48%), Gaps = 44/216 (20%)

Query: 43  EEAGDMVAAQADENV-GEAGRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTF 101
           E+ G+  A  + + + G+ G  L E   + S  D P             KRKQRR+RTTF
Sbjct: 177 EDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPL------------KRKQRRSRTTF 224

Query: 102 NSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERA-MLANK 160
            + QL+ LE+ FERTHYPD + RE+LA+R  LTEARVQVWF NRRA++R+   A  LA  
Sbjct: 225 TAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAF 284

Query: 161 NASL----------------LKSYSGDVTAVEQ---PIVPRPAPRPTDYLSWG------- 194
           N  L                L   +   T + Q     V RP P P   +  G       
Sbjct: 285 NHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAA 344

Query: 195 ---TASPYSAMATYSA-TCANNSPAQGINMANSIAN 226
              T+S Y A  ++S+ + +  +PA   N  N ++N
Sbjct: 345 AADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSN 380


>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
          Length = 343

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 45/66 (68%), Positives = 56/66 (84%)

Query: 89  KKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAK 148
           K K K+RRNRTTF++ QL+ LE+VF++THYPD + RE LA R +LTEARVQVWFQNRRAK
Sbjct: 148 KNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAK 207

Query: 149 FRRNER 154
           +R+ ER
Sbjct: 208 WRKRER 213


>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
          Length = 331

 Score = 96.3 bits (238), Expect = 2e-20
 Identities = 54/113 (47%), Positives = 70/113 (61%), Gaps = 11/113 (9%)

Query: 47  DMVAAQADENVGEAGRSLLESPGLTSGSDT---PQQDNDQLNSEEKKKRKQRRNRTTFNS 103
           DM AA+     G        SP LT  S      ++D   +  E + K KQRR+RT F  
Sbjct: 98  DMGAAERSREPG--------SPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTL 149

Query: 104 SQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAM 156
            QL  LER+F+ THYPDAF+RE+L++R+ L+EARVQVWFQNRRAK R+ E  +
Sbjct: 150 EQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQL 202


>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
          Length = 326

 Score = 95.9 bits (237), Expect = 3e-20
 Identities = 44/62 (70%), Positives = 53/62 (85%)

Query: 93  KQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRN 152
           K+RR+RTTF S QL+ LE+VF++THYPD +VRE LA R  LTEARVQVWFQNRRAK+R+ 
Sbjct: 131 KKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKR 190

Query: 153 ER 154
           ER
Sbjct: 191 ER 192


>gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens]
          Length = 225

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 59/153 (38%), Positives = 87/153 (56%), Gaps = 12/153 (7%)

Query: 16  GGRLDSPGNLDTLQA------KKNFSVSHLLDLEEAGDMVAAQADENVGEAGRSLLESPG 69
           GG+ DS    + L++      +   S S L D+ E G        ++  +  +  L+  G
Sbjct: 27  GGKKDSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFG 86

Query: 70  ---LTSGSDTPQQDNDQLNSEEKK---KRKQRRNRTTFNSSQLQALERVFERTHYPDAFV 123
              +  G    ++  + + SE++    K KQRR+RT F   QL  LER+F+ THYPDAF+
Sbjct: 87  TARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFM 146

Query: 124 REDLARRVNLTEARVQVWFQNRRAKFRRNERAM 156
           RE+L++R+ L+EARVQVWFQNRRAK R+ E  M
Sbjct: 147 REELSQRLGLSEARVQVWFQNRRAKCRKQENQM 179


>gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]
          Length = 292

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 59/153 (38%), Positives = 87/153 (56%), Gaps = 12/153 (7%)

Query: 16  GGRLDSPGNLDTLQA------KKNFSVSHLLDLEEAGDMVAAQADENVGEAGRSLLESPG 69
           GG+ DS    + L++      +   S S L D+ E G        ++  +  +  L+  G
Sbjct: 27  GGKKDSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFG 86

Query: 70  ---LTSGSDTPQQDNDQLNSEEKK---KRKQRRNRTTFNSSQLQALERVFERTHYPDAFV 123
              +  G    ++  + + SE++    K KQRR+RT F   QL  LER+F+ THYPDAF+
Sbjct: 87  TARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFM 146

Query: 124 REDLARRVNLTEARVQVWFQNRRAKFRRNERAM 156
           RE+L++R+ L+EARVQVWFQNRRAK R+ E  M
Sbjct: 147 REELSQRLGLSEARVQVWFQNRRAKCRKQENQM 179


>gi|24234708 paired-like homeodomain transcription factor 2 isoform
           b [Homo sapiens]
          Length = 317

 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 50/106 (47%), Positives = 67/106 (63%), Gaps = 5/106 (4%)

Query: 66  ESPGLTSGSDTPQQDNDQLNSEE-KKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVR 124
           + PG      + Q  N+ + +E+  KK++QRR RT F S QLQ LE  F+R  YPD   R
Sbjct: 56  QHPGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTR 115

Query: 125 EDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSG 170
           E++A   NLTEARV+VWF+NRRAK+R+ ER    N+ A L K+  G
Sbjct: 116 EEIAVWTNLTEARVRVWFKNRRAKWRKRER----NQQAELCKNGFG 157


>gi|87044888 short stature homeobox 2 isoform b [Homo sapiens]
          Length = 190

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 43/73 (58%), Positives = 56/73 (76%)

Query: 84  LNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQ 143
           +  E + K KQRR+RT F   QL  LER+F+ THYPDAF+RE+L++R+ L+EARVQVWFQ
Sbjct: 1   MEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQ 60

Query: 144 NRRAKFRRNERAM 156
           NRRAK R+ E  +
Sbjct: 61  NRRAKCRKQENQL 73


>gi|21361183 paired-like homeodomain transcription factor 2 isoform
           c [Homo sapiens]
          Length = 324

 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 50/105 (47%), Positives = 66/105 (62%), Gaps = 5/105 (4%)

Query: 67  SPGLTSGSDTPQQDNDQLNSEE-KKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVRE 125
           SP       + Q  N+ + +E+  KK++QRR RT F S QLQ LE  F+R  YPD   RE
Sbjct: 64  SPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTRE 123

Query: 126 DLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSG 170
           ++A   NLTEARV+VWF+NRRAK+R+ ER    N+ A L K+  G
Sbjct: 124 EIAVWTNLTEARVRVWFKNRRAKWRKRER----NQQAELCKNGFG 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.125    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,122,560
Number of Sequences: 37866
Number of extensions: 398145
Number of successful extensions: 1994
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 300
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 1574
Number of HSP's gapped (non-prelim): 452
length of query: 245
length of database: 18,247,518
effective HSP length: 100
effective length of query: 145
effective length of database: 14,460,918
effective search space: 2096833110
effective search space used: 2096833110
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.