Guide to the Human Genome
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Search of human proteins with 4504789

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo
sapiens]
         (461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo sapiens]    934   0.0  
gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo sapi...   423   e-118
gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens]    389   e-108
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    40   0.004
gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]      39   0.010
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]             39   0.010
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]    39   0.013
gi|41349454 proline arginine-rich end leucine-rich repeat protei...    38   0.017
gi|4506041 proline arginine-rich end leucine-rich repeat protein...    38   0.017
gi|145309320 forkhead box Q1 [Homo sapiens]                            38   0.022
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]           38   0.022
gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Ho...    37   0.029
gi|57222570 codanin 1 [Homo sapiens]                                   37   0.038
gi|50428940 mediator complex subunit 25 [Homo sapiens]                 37   0.038
gi|58530845 zyxin [Homo sapiens]                                       37   0.038
gi|4508047 zyxin [Homo sapiens]                                        37   0.038
gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo ...    37   0.049
gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo ...    37   0.049
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    37   0.049
gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]            37   0.049
gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]            37   0.049
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     37   0.049
gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens]             36   0.064
gi|239753371 PREDICTED: hypothetical protein [Homo sapiens]            36   0.064
gi|239747938 PREDICTED: hypothetical protein XP_002346476 [Homo ...    36   0.064
gi|239741833 PREDICTED: hypothetical protein XP_002342339 [Homo ...    36   0.064
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]       36   0.064
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       36   0.064
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       36   0.064
gi|22726201 inositol polyphosphate multikinase [Homo sapiens]          36   0.064

>gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo sapiens]
          Length = 461

 Score =  934 bits (2415), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAK 60
           MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAK
Sbjct: 1   MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAK 60

Query: 61  RRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRL 120
           RRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRL
Sbjct: 61  RRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRL 120

Query: 121 STSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVIS 180
           STSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVIS
Sbjct: 121 STSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVIS 180

Query: 181 PFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVER 240
           PFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVER
Sbjct: 181 PFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVER 240

Query: 241 DGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAP 300
           DGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAP
Sbjct: 241 DGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAP 300

Query: 301 TEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFE 360
           TEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFE
Sbjct: 301 TEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFE 360

Query: 361 EFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKT 420
           EFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKT
Sbjct: 361 EFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKT 420

Query: 421 TPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER 461
           TPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER
Sbjct: 421 TPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER 461


>gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo
           sapiens]
          Length = 946

 Score =  423 bits (1088), Expect = e-118
 Identities = 227/399 (56%), Positives = 276/399 (69%), Gaps = 7/399 (1%)

Query: 67  PNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQP-RRLSTSSV 125
           P  LP+ P  P + +    +  P V  T  G  E +       GS     P R+LS+SS 
Sbjct: 545 PELLPQDPDKPFLRKACSPSNIPAVIITDMGTQE-DGALEETQGSPRGNLPLRKLSSSSA 603

Query: 126 SSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQ---KNHWQKIRTMVNL-PVISP 181
           SSTG SS  EDSE+D+ SD E     N       D  +      W+KI+ MV+  P +  
Sbjct: 604 SSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMS 663

Query: 182 FKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVERD 241
           FKK+Y W+QLAGH GSFKAA  +G ILK+  E E+ CL RLM D LR  VPA+HG V +D
Sbjct: 664 FKKKYPWIQLAGHAGSFKAAA-NGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKD 722

Query: 242 GESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPT 301
           GE Y Q+ DLL  FD PCV+DCKMG+RTYLEEELTKAR++P LRKDMY+KM+ VDPEAPT
Sbjct: 723 GERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPT 782

Query: 302 EEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEE 361
           EEE AQRAVTKPRYMQWRE ISS+ TLGFRIEGIKK DG+ + DFK T++REQV   F E
Sbjct: 783 EEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFRE 842

Query: 362 FVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTT 421
           F +G+  +L  Y +RL+ IR TLEVS FF+ HEVIGSSLLF+HD   +A VW+IDFGKTT
Sbjct: 843 FTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTT 902

Query: 422 PLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAE 460
           PLP+GQ L H  PW+EGNREDGYL GL+NL+ IL  +++
Sbjct: 903 PLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQ 941


>gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens]
          Length = 683

 Score =  389 bits (998), Expect = e-108
 Identities = 201/390 (51%), Positives = 265/390 (67%), Gaps = 28/390 (7%)

Query: 72  RAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSSTGSS 131
           +  P   +P+L +T E P+      GPP R        G S                 S+
Sbjct: 320 KCSPLCPVPRLIITPETPEPEAQPVGPPSR------VEGGS-------------GGFSSA 360

Query: 132 SLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNL-PVISPFKKRYAWVQ 190
           S  ++SEDD+++     S         ED      W+K++T++   P +  F+K Y WVQ
Sbjct: 361 SSFDESEDDVVAGGGGASDP-------EDRSGSKPWKKLKTVLKYSPFVVSFRKHYPWVQ 413

Query: 191 LAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVERDGESYLQLQD 250
           L+GH G+F+A G  G ILKR  + E+  L +LM D LR  VPA++G+V +DG+++ Q++D
Sbjct: 414 LSGHAGNFQA-GEDGRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMED 472

Query: 251 LLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAV 310
           LL  F+GP ++DCKMG RTYLEEEL KARERP+ RKDMY+KM+AVDP APT EEHAQ AV
Sbjct: 473 LLADFEGPSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAV 532

Query: 311 TKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVL 370
           TKPRYMQWRE +SS++TLGFRIEGIKKADG+C+T+FK T++ EQV +V E+FV GD  +L
Sbjct: 533 TKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVIL 592

Query: 371 RRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILD 430
           ++Y+  L+++R+ LE+S FF+ HEV+GSSLLFVHDH   A VW+IDFGKT  LPD Q L 
Sbjct: 593 QKYVACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLS 652

Query: 431 HRRPWEEGNREDGYLLGLDNLIGILASLAE 460
           HR PW EGNREDGYL GLDN+I +L  LA+
Sbjct: 653 HRLPWAEGNREDGYLWGLDNMICLLQGLAQ 682


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 5/70 (7%)

Query: 54  PRARGAKRRGG---QVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAG 110
           P+A G+  + G    VP   P+APP+  +PQ    A++P  PPT    P  +   LPA  
Sbjct: 400 PQAAGSSNQPGLLASVPQPKPQAPPSQPLPQ--TQAKQPQAPPTPQQTPSTQAQGLPAQA 457

Query: 111 SSHLQQPRRL 120
            +  Q  ++L
Sbjct: 458 QATPQHQQQL 467


>gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]
          Length = 1159

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 43/137 (31%), Positives = 54/137 (39%), Gaps = 8/137 (5%)

Query: 6   GPTGMARPGG--ARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRG 63
           GP+  ++  G  AR  SPG    PR       LL      A  AA  + EP   G   + 
Sbjct: 5   GPSRASKGPGPTARAPSPGAPPPPRSPRSRPLLLLLLLLGACGAAGRSPEPGRLGPHAQL 64

Query: 64  GQVPNGLP--RAPPAPVIPQLTVTAEEPDVPPTSPGP-PERERDCLPAAGSSHLQQPRRL 120
            +VP   P  RA P            EP  P  SPGP P    D  PAAG  + +  R  
Sbjct: 65  TRVPRSPPAGRAEPGGG-EDRQARGTEPGAPGPSPGPAPGPGEDGAPAAG--YRRWERAA 121

Query: 121 STSSVSSTGSSSLLEDS 137
             + V+S    SL+  S
Sbjct: 122 PLAGVASRAQVSLISTS 138


>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
          Length = 363

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 37/111 (33%), Positives = 44/111 (39%), Gaps = 11/111 (9%)

Query: 46  AAAAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERER-D 104
           AAAAAA    AR     GG+ P G   A       +L    E+   PP  P P   E   
Sbjct: 123 AAAAAAAATAARNNPEPGGRRPEGGLEA------DELLPAREKVAEPPPPPPPHFSETFP 176

Query: 105 CLPAAGSSHLQQPRRLSTSSVSSTGSSSLLE----DSEDDLLSDSESRSRG 151
            LPA G  +     +L  S+    GS    E    DSEDD   DS +   G
Sbjct: 177 SLPAEGKVYSSDEEKLEASAGDPAGSEQEEEGSGGDSEDDGFLDSSAGGPG 227


>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
          Length = 663

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 35/99 (35%), Positives = 37/99 (37%), Gaps = 15/99 (15%)

Query: 2   TLPGGPTGMARPG--GARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGA 59
           T P GP  MA+    G  P S      P           EA  AA  AAA    P A G+
Sbjct: 88  TTPLGPEHMAQASTLGLSPPSQAFPAHP-----------EAPAAAARAAALVAHPGA-GS 135

Query: 60  KRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGP 98
              GG      P APP P  P L  T   P  PP  P P
Sbjct: 136 YPCGGGSSGAQPSAPPPPA-PPLPPTPSPPPPPPPPPPP 173


>gi|41349454 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 4/63 (6%)

Query: 45  VAAAAAAGEPRARGAKRRG-GQVPNGLPRAPPAPVIPQLTVTAEEPDV-PPTSPGPPERE 102
           + A+ A G+P  R     G G+ P   PR  P P  PQ    AE  D+ PP  PGPP   
Sbjct: 13  ILASVAQGQPTRRPRPGTGPGRRPR--PRPRPTPSFPQPDEPAEPTDLPPPLPPGPPSIF 70

Query: 103 RDC 105
            DC
Sbjct: 71  PDC 73


>gi|4506041 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 4/63 (6%)

Query: 45  VAAAAAAGEPRARGAKRRG-GQVPNGLPRAPPAPVIPQLTVTAEEPDV-PPTSPGPPERE 102
           + A+ A G+P  R     G G+ P   PR  P P  PQ    AE  D+ PP  PGPP   
Sbjct: 13  ILASVAQGQPTRRPRPGTGPGRRPR--PRPRPTPSFPQPDEPAEPTDLPPPLPPGPPSIF 70

Query: 103 RDC 105
            DC
Sbjct: 71  PDC 73


>gi|145309320 forkhead box Q1 [Homo sapiens]
          Length = 403

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 40/108 (37%), Positives = 46/108 (42%), Gaps = 29/108 (26%)

Query: 15  GARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAA--AGEPRARGAKRRGGQVPNGLPR 72
           GA PC P L   P        LL  A C A+    A  AGEP   GA  R  +VP   P 
Sbjct: 298 GAAPCPP-LPAFPA-------LLPAAPCRALLPLCAYGAGEPARLGA--REAEVP---PT 344

Query: 73  APPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRL 120
           APP  + P          +P  +P  P R     PAAG +HL  P RL
Sbjct: 345 APPLLLAP----------LPAAAPAKPLRG----PAAGGAHLYCPLRL 378


>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
          Length = 1006

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 5/70 (7%)

Query: 71  PRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSSTGS 130
           P+APP P        AE PD P +SPGP  RE      AG +   +       S  S   
Sbjct: 615 PKAPPGPARAPPGQPAE-PDAPRSSPGPGAREE----GAGGAATPEDGAGGRGSEGSQSP 669

Query: 131 SSLLEDSEDD 140
            S ++D+EDD
Sbjct: 670 GSSVDDAEDD 679



 Score = 32.3 bits (72), Expect = 0.93
 Identities = 25/86 (29%), Positives = 33/86 (38%), Gaps = 12/86 (13%)

Query: 73  APPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSSTGSSS 132
           AP AP  P   V +  P  PPTSPG P+              Q+P    T      GS  
Sbjct: 39  APEAPSPPSADVNSPPPLPPPTSPGGPKELEG----------QEPEPRPTE--EEPGSPW 86

Query: 133 LLEDSEDDLLSDSESRSRGNVQLEAG 158
              D  + ++ D + R R  + L  G
Sbjct: 87  SGPDELEPVVQDGQRRIRARLSLATG 112



 Score = 29.6 bits (65), Expect = 6.0
 Identities = 29/99 (29%), Positives = 36/99 (36%), Gaps = 11/99 (11%)

Query: 4   PGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRG 63
           P GP G A P    P +P   R  RR     R L+E   A        G   A  + R G
Sbjct: 720 PPGPPGPAAPPAPSPAAP--VRTRRR-----RKLYELHAAGAPPPPPPGHAPAPESPRPG 772

Query: 64  ---GQVPNGLPRAPPAPVIPQLTVTAEEPDVP-PTSPGP 98
              G  P   P   P P        +++P  P P +P P
Sbjct: 773 SGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAP 811


>gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Homo
            sapiens]
          Length = 1288

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 45/186 (24%), Positives = 76/186 (40%), Gaps = 24/186 (12%)

Query: 46   AAAAAAGEPRARGAKR-------RGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGP 98
            +A    G+P  +  KR       R    P+  P A P P     T +   P     S  P
Sbjct: 896  SAQTLLGDPFLQPGKRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQTFPCPQAPSQHP 955

Query: 99   PERERDCLPAAGSSHLQQPRRLS----TSSVSSTGSSSLLEDS----------EDDLLSD 144
            P   + CL   G+S L+ P   +     S   S+G S L ++S          E +L + 
Sbjct: 956  PSPPKRCLSYGGTSQLRVPEEPAAEEPASPEESSGLSLLHQESKRRAMLAAVLEQELPAL 1015

Query: 145  SESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVISPFKKRYAWVQLAGHTGSFKAAGTS 204
            +E+  +   Q E G  +G +NH +++   +   + +P +++ A  +L    G  +A G  
Sbjct: 1016 AENLHQEQKQ-EQGARLG-RNHVEELLRCLGAHIHTPNRRQLA-QELRALQGRLRAQGLG 1072

Query: 205  GLILKR 210
              +L R
Sbjct: 1073 PALLHR 1078


>gi|57222570 codanin 1 [Homo sapiens]
          Length = 1227

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 50/162 (30%), Positives = 61/162 (37%), Gaps = 32/162 (19%)

Query: 3   LPGGPTGMARPGGARPCSPGLERA-PRRSVGELRLLF---EARCAAVAAAAAAGEPRARG 58
           LP GP   A+  GA    PG     PR S G    LF   EA+  A  A  A    R RG
Sbjct: 65  LPQGPPTPAKTPGASAALPGRPGGPPRGSRGARSQLFPPTEAQSTAAEAPLARRGGRRRG 124

Query: 59  ---AKRRGGQ------VPNGLP-------RAPPAPVIPQLTVT--------AEEPDVPPT 94
              A+ RGG+          LP       R   +P  P LT++         E P V   
Sbjct: 125 PGPARERGGRGLEEGVSGESLPGAGGRRLRGSGSPSRPSLTLSDPPNLSNLEEFPPVGSV 184

Query: 95  SPGP----PERERDCLPAAGSSHLQQPRRLSTSSVSSTGSSS 132
            PGP    P R  +  P +    L +P+   TS   S   SS
Sbjct: 185 PPGPTGTKPSRRINPTPVSEERSLSKPKTCFTSPPISCVPSS 226


>gi|50428940 mediator complex subunit 25 [Homo sapiens]
          Length = 747

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 34/125 (27%), Positives = 47/125 (37%), Gaps = 14/125 (11%)

Query: 6   GPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQ 65
           G  G   P G  P      R P +++ +LR         V A+ A G+P+ +G  +    
Sbjct: 558 GMGGQQAPPGLGPILEDQAR-PSQNLLQLRPPQPQPQGTVGASGATGQPQPQGTAQPPPG 616

Query: 66  VPNGLPRA-----PPAPVI--------PQLTVTAEEPDVPPTSPGPPERERDCLPAAGSS 112
            P G P A     PP P++        PQL      P  P T   PP+     L   G+ 
Sbjct: 617 APQGPPGAASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAP 676

Query: 113 HLQQP 117
            L  P
Sbjct: 677 ALLPP 681


>gi|58530845 zyxin [Homo sapiens]
          Length = 572

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 39/127 (30%), Positives = 52/127 (40%), Gaps = 11/127 (8%)

Query: 12  RPGGARPC-SPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGL 70
           RPG + P  +PG +RA    VGE+               A     A GA   GG  P   
Sbjct: 40  RPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGAL--GGAFP--- 94

Query: 71  PRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPR-RLSTSSVSSTG 129
              PP P+         E ++ P+ P PPE E    P A      QPR ++S+  +    
Sbjct: 95  --PPPPPIEESFPPAPLEEEIFPSPPPPPEEEGG--PEAPIPPPPQPREKVSSIDLEIDS 150

Query: 130 SSSLLED 136
            SSLL+D
Sbjct: 151 LSSLLDD 157


>gi|4508047 zyxin [Homo sapiens]
          Length = 572

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 39/127 (30%), Positives = 52/127 (40%), Gaps = 11/127 (8%)

Query: 12  RPGGARPC-SPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGL 70
           RPG + P  +PG +RA    VGE+               A     A GA   GG  P   
Sbjct: 40  RPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGAL--GGAFP--- 94

Query: 71  PRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPR-RLSTSSVSSTG 129
              PP P+         E ++ P+ P PPE E    P A      QPR ++S+  +    
Sbjct: 95  --PPPPPIEESFPPAPLEEEIFPSPPPPPEEEGG--PEAPIPPPPQPREKVSSIDLEIDS 150

Query: 130 SSSLLED 136
            SSLL+D
Sbjct: 151 LSSLLDD 157


>gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo
           sapiens]
          Length = 493

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 56/211 (26%), Positives = 78/211 (36%), Gaps = 35/211 (16%)

Query: 13  PGGARPCSPGLERAPRRSVGELRLL-------FEARCAAVAAAAAAGEPRARGAKRRGGQ 65
           P  A P  P   +AP     ++ LL         A  AA AAAAAA    A  A      
Sbjct: 62  PFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAAST 121

Query: 66  VPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSV 125
           V     + PPAP  P   V+A      P +   P      + AA ++ +  P    TS+V
Sbjct: 122 VDTAALKQPPAPPPPPPPVSA------PAAEAAPPASAATIAAAAATAVVAP----TSTV 171

Query: 126 SSTGSSSLLEDSEDD------LLSDSESRSRGNVQLEAGEDVGQK-----NHWQKIRTMV 174
           +    +S LE            L   E ++  N++       G K     +   K+ TMV
Sbjct: 172 AVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMV 231

Query: 175 NLPVISPFKKRYAWVQLAGHTGSFKAAGTSG 205
            L ++S         QL+G  G    AG  G
Sbjct: 232 PLSLLSV-------PQLSGAGGGGGEAGAGG 255


>gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo
           sapiens]
          Length = 477

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 56/211 (26%), Positives = 78/211 (36%), Gaps = 35/211 (16%)

Query: 13  PGGARPCSPGLERAPRRSVGELRLL-------FEARCAAVAAAAAAGEPRARGAKRRGGQ 65
           P  A P  P   +AP     ++ LL         A  AA AAAAAA    A  A      
Sbjct: 62  PFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAAST 121

Query: 66  VPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSV 125
           V     + PPAP  P   V+A      P +   P      + AA ++ +  P    TS+V
Sbjct: 122 VDTAALKQPPAPPPPPPPVSA------PAAEAAPPASAATIAAAAATAVVAP----TSTV 171

Query: 126 SSTGSSSLLEDSEDD------LLSDSESRSRGNVQLEAGEDVGQK-----NHWQKIRTMV 174
           +    +S LE            L   E ++  N++       G K     +   K+ TMV
Sbjct: 172 AVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMV 231

Query: 175 NLPVISPFKKRYAWVQLAGHTGSFKAAGTSG 205
            L ++S         QL+G  G    AG  G
Sbjct: 232 PLSLLSV-------PQLSGAGGGGGEAGAGG 255


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 7/91 (7%)

Query: 64   GQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGP-----PERERDCLPAAGSSHLQQPR 118
            G  P G P        P +T T+E P VPP  P P     PE+E + +  A +     P 
Sbjct: 6255 GPCPRGAPALQETGSQPPVTGTSEAPAVPPRVPQPLLHEGPEQEPEAI--ARAQEWTVPI 6312

Query: 119  RLSTSSVSSTGSSSLLEDSEDDLLSDSESRS 149
            R+  ++    G+  LL D    ++ ++  R+
Sbjct: 6313 RMEGAAWPGAGTGELLWDVHSHVVRETTQRT 6343


>gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 38/115 (33%), Positives = 45/115 (39%), Gaps = 13/115 (11%)

Query: 10  MARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGE--PRARGAKRRGGQVP 67
           MA  GG R  + GL+R P     E  L    R     AA A  +   R RGA   G    
Sbjct: 1   MAISGGPRRLA-GLQRTPAAYANEAALAISGRADEEGAAGAGSKLWRRPRGAVSAGAPGS 59

Query: 68  -----NGLPRAPPAPVIPQLTVTAEEP--DVPP---TSPGPPERERDCLPAAGSS 112
                +  P APP P  P     +E P   + P    SPGP  R   C   AGS+
Sbjct: 60  PLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSA 114


>gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 38/115 (33%), Positives = 45/115 (39%), Gaps = 13/115 (11%)

Query: 10  MARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGE--PRARGAKRRGGQVP 67
           MA  GG R  + GL+R P     E  L    R     AA A  +   R RGA   G    
Sbjct: 1   MAISGGPRRLA-GLQRTPAAYANEAALAISGRADEEGAAGAGSKLWRRPRGAVSAGAPGS 59

Query: 68  -----NGLPRAPPAPVIPQLTVTAEEP--DVPP---TSPGPPERERDCLPAAGSS 112
                +  P APP P  P     +E P   + P    SPGP  R   C   AGS+
Sbjct: 60  PLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSA 114


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 40/147 (27%), Positives = 54/147 (36%), Gaps = 15/147 (10%)

Query: 8   TGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVP 67
           T    PG A+P  P  +RA             A  AA   A AA    A  A  R    P
Sbjct: 157 TAPPSPGPAQP-GPRAQRA-------------APLAAPPPAPAAPPAVAPPAGPRRAPPP 202

Query: 68  NGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSS 127
               R PP P  PQ     ++   PP  P PP  E   + A G++     R +      S
Sbjct: 203 AVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPP-EGGAVRAGGAARPVSLREVVRYLGGS 261

Query: 128 TGSSSLLEDSEDDLLSDSESRSRGNVQ 154
            G+   L       L + E+ +RG ++
Sbjct: 262 GGAGGRLTRGRVQGLLEEEAAARGRLE 288



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 35/123 (28%), Positives = 45/123 (36%), Gaps = 18/123 (14%)

Query: 11  ARPGGARPCSPGLER---APRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKR----RG 63
           ARP   R C     R    P R+  EL  L + R  AV   +  G    R A R    R 
Sbjct: 47  ARPDLERICRMVRRRHGPEPERTRAELEKLIQQR--AVLRVSYKGSISYRNAARVQPPRR 104

Query: 64  GQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTS 123
           G  P   PRAP     P     A  P  P   P P        P A ++  + PR  + +
Sbjct: 105 GATPPAPPRAPRG--APAAAAAAAPPPTPAPPPPP-------APVAAAAPARAPRAAAAA 155

Query: 124 SVS 126
           + +
Sbjct: 156 ATA 158


>gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens]
          Length = 340

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 1/72 (1%)

Query: 48  AAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLP 107
           A A G P A  A      +P G P AP  P    +        +   +PG P R  D  P
Sbjct: 55  AGALGTPAAAAANELNNNLPGGAPAAPAVPGPGGVNCAVGSAMLTRAAPG-PRRSEDEPP 113

Query: 108 AAGSSHLQQPRR 119
           AA +S    P+R
Sbjct: 114 AASASAAPPPQR 125


>gi|239753371 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 119

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 5/75 (6%)

Query: 23  LERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPA-----P 77
           L R PRR      L+  A   A A+AA  G P        GG +P    R   A     P
Sbjct: 40  LFRLPRRGADRAALVAAAAAVAAASAAPPGSPALGNRLHAGGPLPRSASRPTRAGQESGP 99

Query: 78  VIPQLTVTAEEPDVP 92
            +P     AE P +P
Sbjct: 100 FLPPPAARAELPKIP 114


>gi|239747938 PREDICTED: hypothetical protein XP_002346476 [Homo
           sapiens]
          Length = 119

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 5/75 (6%)

Query: 23  LERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPA-----P 77
           L R PRR      L+  A   A A+AA  G P        GG +P    R   A     P
Sbjct: 40  LFRLPRRGADRAALVAAAAAVAAASAAPPGSPALGNRLHAGGPLPRSASRPTRAGQESGP 99

Query: 78  VIPQLTVTAEEPDVP 92
            +P     AE P +P
Sbjct: 100 FLPPPAARAELPKIP 114


>gi|239741833 PREDICTED: hypothetical protein XP_002342339 [Homo
           sapiens]
          Length = 119

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 5/75 (6%)

Query: 23  LERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPA-----P 77
           L R PRR      L+  A   A A+AA  G P        GG +P    R   A     P
Sbjct: 40  LFRLPRRGADRAALVAAAAAVAAASAAPPGSPALGNRLHAGGPLPRSASRPTRAGQESGP 99

Query: 78  VIPQLTVTAEEPDVP 92
            +P     AE P +P
Sbjct: 100 FLPPPAARAELPKIP 114


>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
          Length = 669

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 38  FEARCAAVAAAAAAGEPRAR--GAKRRGGQVPNGLPRAPPAP-VIPQLTVTAEEPDVPPT 94
           F +R        AAG PR R  G    GG  P   P  PP    +P  +     P  PP 
Sbjct: 400 FSSRHPLSPGFGAAGTPRWRSGGLVHSGGARPGLRPSHPPRRRPLPPASSLGHPPAKPPL 459

Query: 95  SPGPPERERDCLPAAGSSHLQQPR 118
            PGP + +    P+A S  L++ R
Sbjct: 460 PPGPVDMQSFRRPSAASIDLRRTR 483



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 17  RPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVP-NGLPRAPP 75
           +P  P +   P++SV +      A+       ++  +  +    ++  Q P +  P+ PP
Sbjct: 227 KPPQPQVGGLPKKSVPQPEFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKKPP 286

Query: 76  APVIPQLTVTAEEPDVP--PTSPGPPE 100
            P +  LT T+ EP+V   P  P P E
Sbjct: 287 QPELGDLTRTSSEPEVSVLPKRPRPAE 313


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 31/103 (30%), Positives = 41/103 (39%), Gaps = 14/103 (13%)

Query: 5   GGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGG 64
           GGP   A P    P SP    +P+R  G  +   +   +  A   A+G P        GG
Sbjct: 538 GGPG--APPAARPPASP----SPQRQAGPPQATRQTSVSGPAPPKASGAPP-------GG 584

Query: 65  QVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLP 107
           Q   G P+ PP P  P    +   P VP T P   ++ R   P
Sbjct: 585 QQRQGPPQKPPGPAGPTRQASQAGP-VPRTGPPTTQQPRPSGP 626


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 31/103 (30%), Positives = 41/103 (39%), Gaps = 14/103 (13%)

Query: 5   GGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGG 64
           GGP   A P    P SP    +P+R  G  +   +   +  A   A+G P        GG
Sbjct: 538 GGPG--APPAARPPASP----SPQRQAGPPQATRQTSVSGPAPPKASGAPP-------GG 584

Query: 65  QVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLP 107
           Q   G P+ PP P  P    +   P VP T P   ++ R   P
Sbjct: 585 QQRQGPPQKPPGPAGPTRQASQAGP-VPRTGPPTTQQPRPSGP 626


>gi|22726201 inositol polyphosphate multikinase [Homo sapiens]
          Length = 416

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 35/154 (22%), Positives = 67/154 (43%), Gaps = 32/154 (20%)

Query: 190 QLAGHTGSFKAAGT----SGLILKRCSEPERY--------------CLARLMADALRGCV 231
           Q+AGH       G      G +LK+   P R               C   ++ + LR  +
Sbjct: 52  QVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLE-LRKYL 110

Query: 232 PAFHGVVE---RDGESYLQLQDLLDGFDGPCVLDCKMGVRTY----LEEELTKARERPKL 284
           P ++G+        + YL+L+D+   F+ PC++D K+G ++Y      E++ +   +  L
Sbjct: 111 PKYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPL 170

Query: 285 RKDMYKKMLAV------DPEAPTEEEHAQRAVTK 312
            +++   +L +           TE +H  R++TK
Sbjct: 171 MEEIGFLVLGMRVYHVHSDSYETENQHYGRSLTK 204


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,624,630
Number of Sequences: 37866
Number of extensions: 1097240
Number of successful extensions: 8097
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 371
Number of HSP's that attempted gapping in prelim test: 7151
Number of HSP's gapped (non-prelim): 1147
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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