BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo sapiens] (461 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo sapiens] 934 0.0 gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo sapi... 423 e-118 gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens] 389 e-108 gi|148277037 AP2 associated kinase 1 [Homo sapiens] 40 0.004 gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] 39 0.010 gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 39 0.010 gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens] 39 0.013 gi|41349454 proline arginine-rich end leucine-rich repeat protei... 38 0.017 gi|4506041 proline arginine-rich end leucine-rich repeat protein... 38 0.017 gi|145309320 forkhead box Q1 [Homo sapiens] 38 0.022 gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 38 0.022 gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Ho... 37 0.029 gi|57222570 codanin 1 [Homo sapiens] 37 0.038 gi|50428940 mediator complex subunit 25 [Homo sapiens] 37 0.038 gi|58530845 zyxin [Homo sapiens] 37 0.038 gi|4508047 zyxin [Homo sapiens] 37 0.038 gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo ... 37 0.049 gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo ... 37 0.049 gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 37 0.049 gi|169213235 PREDICTED: hypothetical protein [Homo sapiens] 37 0.049 gi|169212744 PREDICTED: hypothetical protein [Homo sapiens] 37 0.049 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 37 0.049 gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens] 36 0.064 gi|239753371 PREDICTED: hypothetical protein [Homo sapiens] 36 0.064 gi|239747938 PREDICTED: hypothetical protein XP_002346476 [Homo ... 36 0.064 gi|239741833 PREDICTED: hypothetical protein XP_002342339 [Homo ... 36 0.064 gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 36 0.064 gi|19924099 synapsin I isoform Ia [Homo sapiens] 36 0.064 gi|19924097 synapsin I isoform Ib [Homo sapiens] 36 0.064 gi|22726201 inositol polyphosphate multikinase [Homo sapiens] 36 0.064 >gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo sapiens] Length = 461 Score = 934 bits (2415), Expect = 0.0 Identities = 461/461 (100%), Positives = 461/461 (100%) Query: 1 MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAK 60 MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAK Sbjct: 1 MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAK 60 Query: 61 RRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRL 120 RRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRL Sbjct: 61 RRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRL 120 Query: 121 STSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVIS 180 STSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVIS Sbjct: 121 STSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVIS 180 Query: 181 PFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVER 240 PFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVER Sbjct: 181 PFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVER 240 Query: 241 DGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAP 300 DGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAP Sbjct: 241 DGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAP 300 Query: 301 TEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFE 360 TEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFE Sbjct: 301 TEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFE 360 Query: 361 EFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKT 420 EFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKT Sbjct: 361 EFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKT 420 Query: 421 TPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER 461 TPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER Sbjct: 421 TPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER 461 >gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo sapiens] Length = 946 Score = 423 bits (1088), Expect = e-118 Identities = 227/399 (56%), Positives = 276/399 (69%), Gaps = 7/399 (1%) Query: 67 PNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQP-RRLSTSSV 125 P LP+ P P + + + P V T G E + GS P R+LS+SS Sbjct: 545 PELLPQDPDKPFLRKACSPSNIPAVIITDMGTQE-DGALEETQGSPRGNLPLRKLSSSSA 603 Query: 126 SSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQ---KNHWQKIRTMVNL-PVISP 181 SSTG SS EDSE+D+ SD E N D + W+KI+ MV+ P + Sbjct: 604 SSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMS 663 Query: 182 FKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVERD 241 FKK+Y W+QLAGH GSFKAA +G ILK+ E E+ CL RLM D LR VPA+HG V +D Sbjct: 664 FKKKYPWIQLAGHAGSFKAAA-NGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKD 722 Query: 242 GESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPT 301 GE Y Q+ DLL FD PCV+DCKMG+RTYLEEELTKAR++P LRKDMY+KM+ VDPEAPT Sbjct: 723 GERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPT 782 Query: 302 EEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEE 361 EEE AQRAVTKPRYMQWRE ISS+ TLGFRIEGIKK DG+ + DFK T++REQV F E Sbjct: 783 EEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFRE 842 Query: 362 FVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTT 421 F +G+ +L Y +RL+ IR TLEVS FF+ HEVIGSSLLF+HD +A VW+IDFGKTT Sbjct: 843 FTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTT 902 Query: 422 PLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAE 460 PLP+GQ L H PW+EGNREDGYL GL+NL+ IL +++ Sbjct: 903 PLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQ 941 >gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens] Length = 683 Score = 389 bits (998), Expect = e-108 Identities = 201/390 (51%), Positives = 265/390 (67%), Gaps = 28/390 (7%) Query: 72 RAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSSTGSS 131 + P +P+L +T E P+ GPP R G S S+ Sbjct: 320 KCSPLCPVPRLIITPETPEPEAQPVGPPSR------VEGGS-------------GGFSSA 360 Query: 132 SLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNL-PVISPFKKRYAWVQ 190 S ++SEDD+++ S ED W+K++T++ P + F+K Y WVQ Sbjct: 361 SSFDESEDDVVAGGGGASDP-------EDRSGSKPWKKLKTVLKYSPFVVSFRKHYPWVQ 413 Query: 191 LAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVERDGESYLQLQD 250 L+GH G+F+A G G ILKR + E+ L +LM D LR VPA++G+V +DG+++ Q++D Sbjct: 414 LSGHAGNFQA-GEDGRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMED 472 Query: 251 LLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAV 310 LL F+GP ++DCKMG RTYLEEEL KARERP+ RKDMY+KM+AVDP APT EEHAQ AV Sbjct: 473 LLADFEGPSIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAV 532 Query: 311 TKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVL 370 TKPRYMQWRE +SS++TLGFRIEGIKKADG+C+T+FK T++ EQV +V E+FV GD +L Sbjct: 533 TKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVIL 592 Query: 371 RRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILD 430 ++Y+ L+++R+ LE+S FF+ HEV+GSSLLFVHDH A VW+IDFGKT LPD Q L Sbjct: 593 QKYVACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLS 652 Query: 431 HRRPWEEGNREDGYLLGLDNLIGILASLAE 460 HR PW EGNREDGYL GLDN+I +L LA+ Sbjct: 653 HRLPWAEGNREDGYLWGLDNMICLLQGLAQ 682 >gi|148277037 AP2 associated kinase 1 [Homo sapiens] Length = 961 Score = 40.0 bits (92), Expect = 0.004 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 5/70 (7%) Query: 54 PRARGAKRRGG---QVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAG 110 P+A G+ + G VP P+APP+ +PQ A++P PPT P + LPA Sbjct: 400 PQAAGSSNQPGLLASVPQPKPQAPPSQPLPQ--TQAKQPQAPPTPQQTPSTQAQGLPAQA 457 Query: 111 SSHLQQPRRL 120 + Q ++L Sbjct: 458 QATPQHQQQL 467 >gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] Length = 1159 Score = 38.9 bits (89), Expect = 0.010 Identities = 43/137 (31%), Positives = 54/137 (39%), Gaps = 8/137 (5%) Query: 6 GPTGMARPGG--ARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRG 63 GP+ ++ G AR SPG PR LL A AA + EP G + Sbjct: 5 GPSRASKGPGPTARAPSPGAPPPPRSPRSRPLLLLLLLLGACGAAGRSPEPGRLGPHAQL 64 Query: 64 GQVPNGLP--RAPPAPVIPQLTVTAEEPDVPPTSPGP-PERERDCLPAAGSSHLQQPRRL 120 +VP P RA P EP P SPGP P D PAAG + + R Sbjct: 65 TRVPRSPPAGRAEPGGG-EDRQARGTEPGAPGPSPGPAPGPGEDGAPAAG--YRRWERAA 121 Query: 121 STSSVSSTGSSSLLEDS 137 + V+S SL+ S Sbjct: 122 PLAGVASRAQVSLISTS 138 >gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] Length = 363 Score = 38.9 bits (89), Expect = 0.010 Identities = 37/111 (33%), Positives = 44/111 (39%), Gaps = 11/111 (9%) Query: 46 AAAAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERER-D 104 AAAAAA AR GG+ P G A +L E+ PP P P E Sbjct: 123 AAAAAAAATAARNNPEPGGRRPEGGLEA------DELLPAREKVAEPPPPPPPHFSETFP 176 Query: 105 CLPAAGSSHLQQPRRLSTSSVSSTGSSSLLE----DSEDDLLSDSESRSRG 151 LPA G + +L S+ GS E DSEDD DS + G Sbjct: 177 SLPAEGKVYSSDEEKLEASAGDPAGSEQEEEGSGGDSEDDGFLDSSAGGPG 227 >gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens] Length = 663 Score = 38.5 bits (88), Expect = 0.013 Identities = 35/99 (35%), Positives = 37/99 (37%), Gaps = 15/99 (15%) Query: 2 TLPGGPTGMARPG--GARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGA 59 T P GP MA+ G P S P EA AA AAA P A G+ Sbjct: 88 TTPLGPEHMAQASTLGLSPPSQAFPAHP-----------EAPAAAARAAALVAHPGA-GS 135 Query: 60 KRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGP 98 GG P APP P P L T P PP P P Sbjct: 136 YPCGGGSSGAQPSAPPPPA-PPLPPTPSPPPPPPPPPPP 173 >gi|41349454 proline arginine-rich end leucine-rich repeat protein precursor [Homo sapiens] Length = 382 Score = 38.1 bits (87), Expect = 0.017 Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 45 VAAAAAAGEPRARGAKRRG-GQVPNGLPRAPPAPVIPQLTVTAEEPDV-PPTSPGPPERE 102 + A+ A G+P R G G+ P PR P P PQ AE D+ PP PGPP Sbjct: 13 ILASVAQGQPTRRPRPGTGPGRRPR--PRPRPTPSFPQPDEPAEPTDLPPPLPPGPPSIF 70 Query: 103 RDC 105 DC Sbjct: 71 PDC 73 >gi|4506041 proline arginine-rich end leucine-rich repeat protein precursor [Homo sapiens] Length = 382 Score = 38.1 bits (87), Expect = 0.017 Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 45 VAAAAAAGEPRARGAKRRG-GQVPNGLPRAPPAPVIPQLTVTAEEPDV-PPTSPGPPERE 102 + A+ A G+P R G G+ P PR P P PQ AE D+ PP PGPP Sbjct: 13 ILASVAQGQPTRRPRPGTGPGRRPR--PRPRPTPSFPQPDEPAEPTDLPPPLPPGPPSIF 70 Query: 103 RDC 105 DC Sbjct: 71 PDC 73 >gi|145309320 forkhead box Q1 [Homo sapiens] Length = 403 Score = 37.7 bits (86), Expect = 0.022 Identities = 40/108 (37%), Positives = 46/108 (42%), Gaps = 29/108 (26%) Query: 15 GARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAA--AGEPRARGAKRRGGQVPNGLPR 72 GA PC P L P LL A C A+ A AGEP GA R +VP P Sbjct: 298 GAAPCPP-LPAFPA-------LLPAAPCRALLPLCAYGAGEPARLGA--REAEVP---PT 344 Query: 73 APPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRL 120 APP + P +P +P P R PAAG +HL P RL Sbjct: 345 APPLLLAP----------LPAAAPAKPLRG----PAAGGAHLYCPLRL 378 >gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] Length = 1006 Score = 37.7 bits (86), Expect = 0.022 Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 5/70 (7%) Query: 71 PRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSSTGS 130 P+APP P AE PD P +SPGP RE AG + + S S Sbjct: 615 PKAPPGPARAPPGQPAE-PDAPRSSPGPGAREE----GAGGAATPEDGAGGRGSEGSQSP 669 Query: 131 SSLLEDSEDD 140 S ++D+EDD Sbjct: 670 GSSVDDAEDD 679 Score = 32.3 bits (72), Expect = 0.93 Identities = 25/86 (29%), Positives = 33/86 (38%), Gaps = 12/86 (13%) Query: 73 APPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSSTGSSS 132 AP AP P V + P PPTSPG P+ Q+P T GS Sbjct: 39 APEAPSPPSADVNSPPPLPPPTSPGGPKELEG----------QEPEPRPTE--EEPGSPW 86 Query: 133 LLEDSEDDLLSDSESRSRGNVQLEAG 158 D + ++ D + R R + L G Sbjct: 87 SGPDELEPVVQDGQRRIRARLSLATG 112 Score = 29.6 bits (65), Expect = 6.0 Identities = 29/99 (29%), Positives = 36/99 (36%), Gaps = 11/99 (11%) Query: 4 PGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRG 63 P GP G A P P +P R RR R L+E A G A + R G Sbjct: 720 PPGPPGPAAPPAPSPAAP--VRTRRR-----RKLYELHAAGAPPPPPPGHAPAPESPRPG 772 Query: 64 ---GQVPNGLPRAPPAPVIPQLTVTAEEPDVP-PTSPGP 98 G P P P P +++P P P +P P Sbjct: 773 SGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAP 811 >gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Homo sapiens] Length = 1288 Score = 37.4 bits (85), Expect = 0.029 Identities = 45/186 (24%), Positives = 76/186 (40%), Gaps = 24/186 (12%) Query: 46 AAAAAAGEPRARGAKR-------RGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGP 98 +A G+P + KR R P+ P A P P T + P S P Sbjct: 896 SAQTLLGDPFLQPGKRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQTFPCPQAPSQHP 955 Query: 99 PERERDCLPAAGSSHLQQPRRLS----TSSVSSTGSSSLLEDS----------EDDLLSD 144 P + CL G+S L+ P + S S+G S L ++S E +L + Sbjct: 956 PSPPKRCLSYGGTSQLRVPEEPAAEEPASPEESSGLSLLHQESKRRAMLAAVLEQELPAL 1015 Query: 145 SESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVISPFKKRYAWVQLAGHTGSFKAAGTS 204 +E+ + Q E G +G +NH +++ + + +P +++ A +L G +A G Sbjct: 1016 AENLHQEQKQ-EQGARLG-RNHVEELLRCLGAHIHTPNRRQLA-QELRALQGRLRAQGLG 1072 Query: 205 GLILKR 210 +L R Sbjct: 1073 PALLHR 1078 >gi|57222570 codanin 1 [Homo sapiens] Length = 1227 Score = 37.0 bits (84), Expect = 0.038 Identities = 50/162 (30%), Positives = 61/162 (37%), Gaps = 32/162 (19%) Query: 3 LPGGPTGMARPGGARPCSPGLERA-PRRSVGELRLLF---EARCAAVAAAAAAGEPRARG 58 LP GP A+ GA PG PR S G LF EA+ A A A R RG Sbjct: 65 LPQGPPTPAKTPGASAALPGRPGGPPRGSRGARSQLFPPTEAQSTAAEAPLARRGGRRRG 124 Query: 59 ---AKRRGGQ------VPNGLP-------RAPPAPVIPQLTVT--------AEEPDVPPT 94 A+ RGG+ LP R +P P LT++ E P V Sbjct: 125 PGPARERGGRGLEEGVSGESLPGAGGRRLRGSGSPSRPSLTLSDPPNLSNLEEFPPVGSV 184 Query: 95 SPGP----PERERDCLPAAGSSHLQQPRRLSTSSVSSTGSSS 132 PGP P R + P + L +P+ TS S SS Sbjct: 185 PPGPTGTKPSRRINPTPVSEERSLSKPKTCFTSPPISCVPSS 226 >gi|50428940 mediator complex subunit 25 [Homo sapiens] Length = 747 Score = 37.0 bits (84), Expect = 0.038 Identities = 34/125 (27%), Positives = 47/125 (37%), Gaps = 14/125 (11%) Query: 6 GPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQ 65 G G P G P R P +++ +LR V A+ A G+P+ +G + Sbjct: 558 GMGGQQAPPGLGPILEDQAR-PSQNLLQLRPPQPQPQGTVGASGATGQPQPQGTAQPPPG 616 Query: 66 VPNGLPRA-----PPAPVI--------PQLTVTAEEPDVPPTSPGPPERERDCLPAAGSS 112 P G P A PP P++ PQL P P T PP+ L G+ Sbjct: 617 APQGPPGAASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAP 676 Query: 113 HLQQP 117 L P Sbjct: 677 ALLPP 681 >gi|58530845 zyxin [Homo sapiens] Length = 572 Score = 37.0 bits (84), Expect = 0.038 Identities = 39/127 (30%), Positives = 52/127 (40%), Gaps = 11/127 (8%) Query: 12 RPGGARPC-SPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGL 70 RPG + P +PG +RA VGE+ A A GA GG P Sbjct: 40 RPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGAL--GGAFP--- 94 Query: 71 PRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPR-RLSTSSVSSTG 129 PP P+ E ++ P+ P PPE E P A QPR ++S+ + Sbjct: 95 --PPPPPIEESFPPAPLEEEIFPSPPPPPEEEGG--PEAPIPPPPQPREKVSSIDLEIDS 150 Query: 130 SSSLLED 136 SSLL+D Sbjct: 151 LSSLLDD 157 >gi|4508047 zyxin [Homo sapiens] Length = 572 Score = 37.0 bits (84), Expect = 0.038 Identities = 39/127 (30%), Positives = 52/127 (40%), Gaps = 11/127 (8%) Query: 12 RPGGARPC-SPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGL 70 RPG + P +PG +RA VGE+ A A GA GG P Sbjct: 40 RPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGAL--GGAFP--- 94 Query: 71 PRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPR-RLSTSSVSSTG 129 PP P+ E ++ P+ P PPE E P A QPR ++S+ + Sbjct: 95 --PPPPPIEESFPPAPLEEEIFPSPPPPPEEEGG--PEAPIPPPPQPREKVSSIDLEIDS 150 Query: 130 SSSLLED 136 SSLL+D Sbjct: 151 LSSLLDD 157 >gi|110347459 MYC-associated zinc finger protein isoform 2 [Homo sapiens] Length = 493 Score = 36.6 bits (83), Expect = 0.049 Identities = 56/211 (26%), Positives = 78/211 (36%), Gaps = 35/211 (16%) Query: 13 PGGARPCSPGLERAPRRSVGELRLL-------FEARCAAVAAAAAAGEPRARGAKRRGGQ 65 P A P P +AP ++ LL A AA AAAAAA A A Sbjct: 62 PFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAAST 121 Query: 66 VPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSV 125 V + PPAP P V+A P + P + AA ++ + P TS+V Sbjct: 122 VDTAALKQPPAPPPPPPPVSA------PAAEAAPPASAATIAAAAATAVVAP----TSTV 171 Query: 126 SSTGSSSLLEDSEDD------LLSDSESRSRGNVQLEAGEDVGQK-----NHWQKIRTMV 174 + +S LE L E ++ N++ G K + K+ TMV Sbjct: 172 AVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMV 231 Query: 175 NLPVISPFKKRYAWVQLAGHTGSFKAAGTSG 205 L ++S QL+G G AG G Sbjct: 232 PLSLLSV-------PQLSGAGGGGGEAGAGG 255 >gi|110347461 MYC-associated zinc finger protein isoform 1 [Homo sapiens] Length = 477 Score = 36.6 bits (83), Expect = 0.049 Identities = 56/211 (26%), Positives = 78/211 (36%), Gaps = 35/211 (16%) Query: 13 PGGARPCSPGLERAPRRSVGELRLL-------FEARCAAVAAAAAAGEPRARGAKRRGGQ 65 P A P P +AP ++ LL A AA AAAAAA A A Sbjct: 62 PFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAAST 121 Query: 66 VPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSV 125 V + PPAP P V+A P + P + AA ++ + P TS+V Sbjct: 122 VDTAALKQPPAPPPPPPPVSA------PAAEAAPPASAATIAAAAATAVVAP----TSTV 171 Query: 126 SSTGSSSLLEDSEDD------LLSDSESRSRGNVQLEAGEDVGQK-----NHWQKIRTMV 174 + +S LE L E ++ N++ G K + K+ TMV Sbjct: 172 AVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMV 231 Query: 175 NLPVISPFKKRYAWVQLAGHTGSFKAAGTSG 205 L ++S QL+G G AG G Sbjct: 232 PLSLLSV-------PQLSGAGGGGGEAGAGG 255 >gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF isoform b [Homo sapiens] Length = 7968 Score = 36.6 bits (83), Expect = 0.049 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 7/91 (7%) Query: 64 GQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGP-----PERERDCLPAAGSSHLQQPR 118 G P G P P +T T+E P VPP P P PE+E + + A + P Sbjct: 6255 GPCPRGAPALQETGSQPPVTGTSEAPAVPPRVPQPLLHEGPEQEPEAI--ARAQEWTVPI 6312 Query: 119 RLSTSSVSSTGSSSLLEDSEDDLLSDSESRS 149 R+ ++ G+ LL D ++ ++ R+ Sbjct: 6313 RMEGAAWPGAGTGELLWDVHSHVVRETTQRT 6343 >gi|169213235 PREDICTED: hypothetical protein [Homo sapiens] Length = 308 Score = 36.6 bits (83), Expect = 0.049 Identities = 38/115 (33%), Positives = 45/115 (39%), Gaps = 13/115 (11%) Query: 10 MARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGE--PRARGAKRRGGQVP 67 MA GG R + GL+R P E L R AA A + R RGA G Sbjct: 1 MAISGGPRRLA-GLQRTPAAYANEAALAISGRADEEGAAGAGSKLWRRPRGAVSAGAPGS 59 Query: 68 -----NGLPRAPPAPVIPQLTVTAEEP--DVPP---TSPGPPERERDCLPAAGSS 112 + P APP P P +E P + P SPGP R C AGS+ Sbjct: 60 PLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSA 114 >gi|169212744 PREDICTED: hypothetical protein [Homo sapiens] Length = 308 Score = 36.6 bits (83), Expect = 0.049 Identities = 38/115 (33%), Positives = 45/115 (39%), Gaps = 13/115 (11%) Query: 10 MARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGE--PRARGAKRRGGQVP 67 MA GG R + GL+R P E L R AA A + R RGA G Sbjct: 1 MAISGGPRRLA-GLQRTPAAYANEAALAISGRADEEGAAGAGSKLWRRPRGAVSAGAPGS 59 Query: 68 -----NGLPRAPPAPVIPQLTVTAEEP--DVPP---TSPGPPERERDCLPAAGSS 112 + P APP P P +E P + P SPGP R C AGS+ Sbjct: 60 PLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSA 114 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 36.6 bits (83), Expect = 0.049 Identities = 40/147 (27%), Positives = 54/147 (36%), Gaps = 15/147 (10%) Query: 8 TGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVP 67 T PG A+P P +RA A AA A AA A A R P Sbjct: 157 TAPPSPGPAQP-GPRAQRA-------------APLAAPPPAPAAPPAVAPPAGPRRAPPP 202 Query: 68 NGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSS 127 R PP P PQ ++ PP P PP E + A G++ R + S Sbjct: 203 AVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPP-EGGAVRAGGAARPVSLREVVRYLGGS 261 Query: 128 TGSSSLLEDSEDDLLSDSESRSRGNVQ 154 G+ L L + E+ +RG ++ Sbjct: 262 GGAGGRLTRGRVQGLLEEEAAARGRLE 288 Score = 31.6 bits (70), Expect = 1.6 Identities = 35/123 (28%), Positives = 45/123 (36%), Gaps = 18/123 (14%) Query: 11 ARPGGARPCSPGLER---APRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKR----RG 63 ARP R C R P R+ EL L + R AV + G R A R R Sbjct: 47 ARPDLERICRMVRRRHGPEPERTRAELEKLIQQR--AVLRVSYKGSISYRNAARVQPPRR 104 Query: 64 GQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTS 123 G P PRAP P A P P P P P A ++ + PR + + Sbjct: 105 GATPPAPPRAPRG--APAAAAAAAPPPTPAPPPPP-------APVAAAAPARAPRAAAAA 155 Query: 124 SVS 126 + + Sbjct: 156 ATA 158 >gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens] Length = 340 Score = 36.2 bits (82), Expect = 0.064 Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 1/72 (1%) Query: 48 AAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLP 107 A A G P A A +P G P AP P + + +PG P R D P Sbjct: 55 AGALGTPAAAAANELNNNLPGGAPAAPAVPGPGGVNCAVGSAMLTRAAPG-PRRSEDEPP 113 Query: 108 AAGSSHLQQPRR 119 AA +S P+R Sbjct: 114 AASASAAPPPQR 125 >gi|239753371 PREDICTED: hypothetical protein [Homo sapiens] Length = 119 Score = 36.2 bits (82), Expect = 0.064 Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 5/75 (6%) Query: 23 LERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPA-----P 77 L R PRR L+ A A A+AA G P GG +P R A P Sbjct: 40 LFRLPRRGADRAALVAAAAAVAAASAAPPGSPALGNRLHAGGPLPRSASRPTRAGQESGP 99 Query: 78 VIPQLTVTAEEPDVP 92 +P AE P +P Sbjct: 100 FLPPPAARAELPKIP 114 >gi|239747938 PREDICTED: hypothetical protein XP_002346476 [Homo sapiens] Length = 119 Score = 36.2 bits (82), Expect = 0.064 Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 5/75 (6%) Query: 23 LERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPA-----P 77 L R PRR L+ A A A+AA G P GG +P R A P Sbjct: 40 LFRLPRRGADRAALVAAAAAVAAASAAPPGSPALGNRLHAGGPLPRSASRPTRAGQESGP 99 Query: 78 VIPQLTVTAEEPDVP 92 +P AE P +P Sbjct: 100 FLPPPAARAELPKIP 114 >gi|239741833 PREDICTED: hypothetical protein XP_002342339 [Homo sapiens] Length = 119 Score = 36.2 bits (82), Expect = 0.064 Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 5/75 (6%) Query: 23 LERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPA-----P 77 L R PRR L+ A A A+AA G P GG +P R A P Sbjct: 40 LFRLPRRGADRAALVAAAAAVAAASAAPPGSPALGNRLHAGGPLPRSASRPTRAGQESGP 99 Query: 78 VIPQLTVTAEEPDVP 92 +P AE P +P Sbjct: 100 FLPPPAARAELPKIP 114 >gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] Length = 669 Score = 36.2 bits (82), Expect = 0.064 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 3/84 (3%) Query: 38 FEARCAAVAAAAAAGEPRAR--GAKRRGGQVPNGLPRAPPAP-VIPQLTVTAEEPDVPPT 94 F +R AAG PR R G GG P P PP +P + P PP Sbjct: 400 FSSRHPLSPGFGAAGTPRWRSGGLVHSGGARPGLRPSHPPRRRPLPPASSLGHPPAKPPL 459 Query: 95 SPGPPERERDCLPAAGSSHLQQPR 118 PGP + + P+A S L++ R Sbjct: 460 PPGPVDMQSFRRPSAASIDLRRTR 483 Score = 32.0 bits (71), Expect = 1.2 Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 3/87 (3%) Query: 17 RPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVP-NGLPRAPP 75 +P P + P++SV + A+ ++ + + ++ Q P + P+ PP Sbjct: 227 KPPQPQVGGLPKKSVPQPEFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKKPP 286 Query: 76 APVIPQLTVTAEEPDVP--PTSPGPPE 100 P + LT T+ EP+V P P P E Sbjct: 287 QPELGDLTRTSSEPEVSVLPKRPRPAE 313 >gi|19924099 synapsin I isoform Ia [Homo sapiens] Length = 705 Score = 36.2 bits (82), Expect = 0.064 Identities = 31/103 (30%), Positives = 41/103 (39%), Gaps = 14/103 (13%) Query: 5 GGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGG 64 GGP A P P SP +P+R G + + + A A+G P GG Sbjct: 538 GGPG--APPAARPPASP----SPQRQAGPPQATRQTSVSGPAPPKASGAPP-------GG 584 Query: 65 QVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLP 107 Q G P+ PP P P + P VP T P ++ R P Sbjct: 585 QQRQGPPQKPPGPAGPTRQASQAGP-VPRTGPPTTQQPRPSGP 626 >gi|19924097 synapsin I isoform Ib [Homo sapiens] Length = 669 Score = 36.2 bits (82), Expect = 0.064 Identities = 31/103 (30%), Positives = 41/103 (39%), Gaps = 14/103 (13%) Query: 5 GGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGG 64 GGP A P P SP +P+R G + + + A A+G P GG Sbjct: 538 GGPG--APPAARPPASP----SPQRQAGPPQATRQTSVSGPAPPKASGAPP-------GG 584 Query: 65 QVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLP 107 Q G P+ PP P P + P VP T P ++ R P Sbjct: 585 QQRQGPPQKPPGPAGPTRQASQAGP-VPRTGPPTTQQPRPSGP 626 >gi|22726201 inositol polyphosphate multikinase [Homo sapiens] Length = 416 Score = 36.2 bits (82), Expect = 0.064 Identities = 35/154 (22%), Positives = 67/154 (43%), Gaps = 32/154 (20%) Query: 190 QLAGHTGSFKAAGT----SGLILKRCSEPERY--------------CLARLMADALRGCV 231 Q+AGH G G +LK+ P R C ++ + LR + Sbjct: 52 QVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLE-LRKYL 110 Query: 232 PAFHGVVE---RDGESYLQLQDLLDGFDGPCVLDCKMGVRTY----LEEELTKARERPKL 284 P ++G+ + YL+L+D+ F+ PC++D K+G ++Y E++ + + L Sbjct: 111 PKYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPL 170 Query: 285 RKDMYKKMLAV------DPEAPTEEEHAQRAVTK 312 +++ +L + TE +H R++TK Sbjct: 171 MEEIGFLVLGMRVYHVHSDSYETENQHYGRSLTK 204 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,624,630 Number of Sequences: 37866 Number of extensions: 1097240 Number of successful extensions: 8097 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 57 Number of HSP's successfully gapped in prelim test: 371 Number of HSP's that attempted gapping in prelim test: 7151 Number of HSP's gapped (non-prelim): 1147 length of query: 461 length of database: 18,247,518 effective HSP length: 106 effective length of query: 355 effective length of database: 14,233,722 effective search space: 5052971310 effective search space used: 5052971310 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.