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Search of human proteins with 4503539
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
isoform 1 [Homo sapiens]
(907 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i... 1809 0.0
gi|110630018 eukaryotic translation initiation factor 4 gamma, 2... 1714 0.0
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 196 8e-50
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 196 8e-50
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 196 8e-50
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 196 8e-50
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 196 8e-50
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ... 190 5e-48
gi|7661744 basic leucine zipper and W2 domains 2 [Homo sapiens] 52 2e-06
gi|229577398 basic leucine zipper and W2 domains 2 [Homo sapiens] 52 2e-06
gi|21735598 programmed cell death 4 isoform 2 [Homo sapiens] 49 2e-05
gi|21735596 programmed cell death 4 isoform 1 [Homo sapiens] 49 2e-05
gi|83267879 eukaryotic translation initiation factor 2B, subunit... 45 4e-04
gi|34452730 poly(A) binding protein interacting protein 1 isofor... 43 0.002
gi|33386693 poly(A) binding protein interacting protein 1 isofor... 43 0.002
gi|17511255 poly(A) binding protein interacting protein 1 isofor... 43 0.002
gi|56549696 E1A binding protein p400 [Homo sapiens] 42 0.003
gi|41281429 basic leucine zipper and W2 domains 1 [Homo sapiens] 41 0.004
gi|7662112 hypothetical protein LOC9811 isoform 1 [Homo sapiens] 41 0.006
gi|169212085 PREDICTED: similar to poly(A) binding protein inter... 40 0.010
gi|239752553 PREDICTED: similar to poly(A) binding protein inter... 40 0.010
gi|89041275 PREDICTED: similar to poly(A) binding protein intera... 40 0.010
gi|215422401 hypothetical protein LOC9811 isoform 2 [Homo sapiens] 39 0.017
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 38 0.037
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 38 0.037
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 38 0.037
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 38 0.037
gi|50428940 mediator complex subunit 25 [Homo sapiens] 38 0.037
gi|21361337 eukaryotic translation initiation factor 5 [Homo sap... 38 0.049
gi|37537716 eukaryotic translation initiation factor 5 [Homo sap... 38 0.049
>gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
isoform 1 [Homo sapiens]
Length = 907
Score = 1809 bits (4685), Expect = 0.0
Identities = 907/907 (100%), Positives = 907/907 (100%)
Query: 1 MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDD 60
MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDD
Sbjct: 1 MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDD 60
Query: 61 NSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVD 120
NSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVD
Sbjct: 61 NSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVD 120
Query: 121 KALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTR 180
KALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTR
Sbjct: 121 KALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTR 180
Query: 181 NVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKK 240
NVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKK
Sbjct: 181 NVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKK 240
Query: 241 RVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQD 300
RVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQD
Sbjct: 241 RVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQD 300
Query: 301 TVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPR 360
TVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPR
Sbjct: 301 TVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPR 360
Query: 361 MKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQS 420
MKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQS
Sbjct: 361 MKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQS 420
Query: 421 QFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSF 480
QFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSF
Sbjct: 421 QFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSF 480
Query: 481 LMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPS 540
LMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPS
Sbjct: 481 LMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPS 540
Query: 541 KEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKA 600
KEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKA
Sbjct: 541 KEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKA 600
Query: 601 SSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISE 660
SSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISE
Sbjct: 601 SSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISE 660
Query: 661 LAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILE 720
LAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILE
Sbjct: 661 LAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILE 720
Query: 721 GKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYI 780
GKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYI
Sbjct: 721 GKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYI 780
Query: 781 SSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYN 840
SSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYN
Sbjct: 781 SSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYN 840
Query: 841 SNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEE 900
SNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEE
Sbjct: 841 SNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEE 900
Query: 901 ESEEEAD 907
ESEEEAD
Sbjct: 901 ESEEEAD 907
>gi|110630018 eukaryotic translation initiation factor 4 gamma, 2
isoform 2 [Homo sapiens]
Length = 869
Score = 1714 bits (4440), Expect = 0.0
Identities = 869/907 (95%), Positives = 869/907 (95%), Gaps = 38/907 (4%)
Query: 1 MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDD 60
MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDD
Sbjct: 1 MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDD 60
Query: 61 NSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVD 120
NSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVD
Sbjct: 61 NSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVD 120
Query: 121 KALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTR 180
KALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTR
Sbjct: 121 KALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTR 180
Query: 181 NVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKK 240
NVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKK
Sbjct: 181 NVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKK 240
Query: 241 RVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQD 300
RVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQD
Sbjct: 241 RVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQD 300
Query: 301 TVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPR 360
TVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPR
Sbjct: 301 TVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPR 360
Query: 361 MKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQS 420
MKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQS
Sbjct: 361 MKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQS 420
Query: 421 QFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSF 480
QFGEMGGKFMKSQ ISLRPAQSF
Sbjct: 421 QFGEMGGKFMKSQ--------------------------------------ISLRPAQSF 442
Query: 481 LMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPS 540
LMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPS
Sbjct: 443 LMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPS 502
Query: 541 KEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKA 600
KEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKA
Sbjct: 503 KEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKA 562
Query: 601 SSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISE 660
SSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISE
Sbjct: 563 SSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISE 622
Query: 661 LAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILE 720
LAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILE
Sbjct: 623 LAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILE 682
Query: 721 GKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYI 780
GKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYI
Sbjct: 683 GKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYI 742
Query: 781 SSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYN 840
SSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYN
Sbjct: 743 SSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYN 802
Query: 841 SNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEE 900
SNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEE
Sbjct: 803 SNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEE 862
Query: 901 ESEEEAD 907
ESEEEAD
Sbjct: 863 ESEEEAD 869
>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 196 bits (498), Expect = 8e-50
Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)
Query: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80
G R P+ T +E + + A W P+ D A+ + D +FR+
Sbjct: 707 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 763
Query: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139
VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L
Sbjct: 764 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 823
Query: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192
A P + P + FR+LL+++ Q EFE + +V++K++ +
Sbjct: 824 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 875
Query: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247
L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+
Sbjct: 876 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 929
Query: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307
E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR
Sbjct: 930 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 988
Query: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359
+WVPR+ D GPKTI+QI ++A +++ I SD GP PP
Sbjct: 989 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 1039
Score = 113 bits (282), Expect = 9e-25
Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)
Query: 530 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589
P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + +
Sbjct: 1228 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1286
Query: 590 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649
L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+
Sbjct: 1287 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1346
Query: 650 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704
+ V + EL +PL G L L L L K + + L++++ ++ ++
Sbjct: 1347 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1406
Query: 705 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755
LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+
Sbjct: 1407 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1465
Query: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815
N+S + V V LMT+ S+ + L + +L + +
Sbjct: 1466 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1510
Query: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874
+QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+
Sbjct: 1511 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1569
Query: 875 QEFPGKGKALFQVNQWLTWLETAEEE 900
E GKG AL V + WL AEEE
Sbjct: 1570 AEQQGKGVALKSVTAFFKWLREAEEE 1595
>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
isoform 2 [Homo sapiens]
Length = 1512
Score = 196 bits (498), Expect = 8e-50
Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)
Query: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80
G R P+ T +E + + A W P+ D A+ + D +FR+
Sbjct: 620 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 676
Query: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139
VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L
Sbjct: 677 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 736
Query: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192
A P + P + FR+LL+++ Q EFE + +V++K++ +
Sbjct: 737 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 788
Query: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247
L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+
Sbjct: 789 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 842
Query: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307
E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR
Sbjct: 843 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 901
Query: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359
+WVPR+ D GPKTI+QI ++A +++ I SD GP PP
Sbjct: 902 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 952
Score = 113 bits (282), Expect = 9e-25
Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)
Query: 530 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589
P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + +
Sbjct: 1141 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1199
Query: 590 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649
L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+
Sbjct: 1200 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1259
Query: 650 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704
+ V + EL +PL G L L L L K + + L++++ ++ ++
Sbjct: 1260 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1319
Query: 705 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755
LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+
Sbjct: 1320 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1378
Query: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815
N+S + V V LMT+ S+ + L + +L + +
Sbjct: 1379 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1423
Query: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874
+QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+
Sbjct: 1424 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1482
Query: 875 QEFPGKGKALFQVNQWLTWLETAEEE 900
E GKG AL V + WL AEEE
Sbjct: 1483 AEQQGKGVALKSVTAFFKWLREAEEE 1508
>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
isoform 3 [Homo sapiens]
Length = 1435
Score = 196 bits (498), Expect = 8e-50
Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)
Query: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80
G R P+ T +E + + A W P+ D A+ + D +FR+
Sbjct: 543 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 599
Query: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139
VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L
Sbjct: 600 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 659
Query: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192
A P + P + FR+LL+++ Q EFE + +V++K++ +
Sbjct: 660 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 711
Query: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247
L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+
Sbjct: 712 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 765
Query: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307
E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR
Sbjct: 766 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 824
Query: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359
+WVPR+ D GPKTI+QI ++A +++ I SD GP PP
Sbjct: 825 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 875
Score = 113 bits (282), Expect = 9e-25
Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)
Query: 530 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589
P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + +
Sbjct: 1064 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1122
Query: 590 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649
L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+
Sbjct: 1123 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1182
Query: 650 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704
+ V + EL +PL G L L L L K + + L++++ ++ ++
Sbjct: 1183 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1242
Query: 705 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755
LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+
Sbjct: 1243 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1301
Query: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815
N+S + V V LMT+ S+ + L + +L + +
Sbjct: 1302 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1346
Query: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874
+QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+
Sbjct: 1347 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1405
Query: 875 QEFPGKGKALFQVNQWLTWLETAEEE 900
E GKG AL V + WL AEEE
Sbjct: 1406 AEQQGKGVALKSVTAFFKWLREAEEE 1431
>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 196 bits (498), Expect = 8e-50
Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)
Query: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80
G R P+ T +E + + A W P+ D A+ + D +FR+
Sbjct: 707 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 763
Query: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139
VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L
Sbjct: 764 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 823
Query: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192
A P + P + FR+LL+++ Q EFE + +V++K++ +
Sbjct: 824 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 875
Query: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247
L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+
Sbjct: 876 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 929
Query: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307
E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR
Sbjct: 930 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 988
Query: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359
+WVPR+ D GPKTI+QI ++A +++ I SD GP PP
Sbjct: 989 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 1039
Score = 113 bits (282), Expect = 9e-25
Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)
Query: 530 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589
P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + +
Sbjct: 1228 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1286
Query: 590 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649
L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+
Sbjct: 1287 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1346
Query: 650 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704
+ V + EL +PL G L L L L K + + L++++ ++ ++
Sbjct: 1347 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1406
Query: 705 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755
LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+
Sbjct: 1407 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1465
Query: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815
N+S + V V LMT+ S+ + L + +L + +
Sbjct: 1466 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1510
Query: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874
+QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+
Sbjct: 1511 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1569
Query: 875 QEFPGKGKALFQVNQWLTWLETAEEE 900
E GKG AL V + WL AEEE
Sbjct: 1570 AEQQGKGVALKSVTAFFKWLREAEEE 1595
>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
isoform 4 [Homo sapiens]
Length = 1403
Score = 196 bits (498), Expect = 8e-50
Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)
Query: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80
G R P+ T +E + + A W P+ D A+ + D +FR+
Sbjct: 511 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 567
Query: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139
VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L
Sbjct: 568 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 627
Query: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192
A P + P + FR+LL+++ Q EFE + +V++K++ +
Sbjct: 628 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 679
Query: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247
L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+
Sbjct: 680 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 733
Query: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307
E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR
Sbjct: 734 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 792
Query: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359
+WVPR+ D GPKTI+QI ++A +++ I SD GP PP
Sbjct: 793 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 843
Score = 113 bits (282), Expect = 9e-25
Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)
Query: 530 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589
P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + +
Sbjct: 1032 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1090
Query: 590 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649
L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+
Sbjct: 1091 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1150
Query: 650 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704
+ V + EL +PL G L L L L K + + L++++ ++ ++
Sbjct: 1151 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1210
Query: 705 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755
LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+
Sbjct: 1211 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1269
Query: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815
N+S + V V LMT+ S+ + L + +L + +
Sbjct: 1270 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1314
Query: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874
+QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+
Sbjct: 1315 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1373
Query: 875 QEFPGKGKALFQVNQWLTWLETAEEE 900
E GKG AL V + WL AEEE
Sbjct: 1374 AEQQGKGVALKSVTAFFKWLREAEEE 1399
>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo
sapiens]
Length = 1585
Score = 190 bits (483), Expect = 5e-48
Identities = 119/293 (40%), Positives = 179/293 (61%), Gaps = 34/293 (11%)
Query: 50 WIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKL 109
W P S +RD S A++ N K + +FRKVR ILNKLTP+ F++L ++ + V+++
Sbjct: 733 WKP--SQKRD--SQADDPENIKTQE--LFRKVRSILNKLTPQMFNQLMKQVSGLTVDTEE 786
Query: 110 ILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLIS 169
LKGVI L+ +KA++EP +S YA +C L P A+ +PG + FR+LL++
Sbjct: 787 RLKGVIDLVFEKAIDEPSFSVAYANMCRCLV----TLKVPMAD-KPGN--TVNFRKLLLN 839
Query: 170 KLQDEFENRTRNVDVYDKRENPL----LPEE--------EEQRAIAKIKMLGNIKFIGEL 217
+ Q EFE + DV++K++ L PEE EE + A+ + +GNIKFIGEL
Sbjct: 840 RCQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGEL 899
Query: 218 GKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQY 277
KL ++ E+I+H C+ LL+ E LECLC+++ T+G LD E+AK MDQY
Sbjct: 900 FKLKMLTEAIMHDCVVKLLKNHDE-------ESLECLCRLLTTIGKDLDFEKAKPRMDQY 952
Query: 278 FARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDA 330
F +M ++ ++ +RIRF+LQD ++LR +WV R+A D GPKTI QI ++A
Sbjct: 953 FNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRA--DQGPKTIEQIHKEA 1003
Score = 103 bits (257), Expect = 7e-22
Identities = 95/385 (24%), Positives = 172/385 (44%), Gaps = 39/385 (10%)
Query: 540 SKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEK 599
S+EEL + +++++ E+L+ + EA+ V E+ A + L + + +L+RS ++
Sbjct: 1218 SEEELERKSKSIIDEFLHINDFKEAMQCVEELNA-QGLLHVFVRVGVESTLERSQITRDH 1276
Query: 600 ASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSIS 659
L+ L Q + +F + F L+ + +DIP + YLA+ + +S+
Sbjct: 1277 MGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMR 1336
Query: 660 EL----AQPL-ESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPE------- 707
EL ++PL G L L L K + + L++++ ++ + LPE
Sbjct: 1337 ELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNF 1396
Query: 708 --------IDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNIS 759
I+ + E L K LS +LEK +++ D + I+ W++ N+
Sbjct: 1397 LLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKAND---EQIFDWVEANLD 1453
Query: 760 PKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKF 819
+ + +FL+ + + V + DSS+ + ++ P++ K+
Sbjct: 1454 E--------IQMSSPTFLRALMTAVCKAAIIADSST------FRVDTAVIKQRVPILLKY 1499
Query: 820 LHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-ITQEFP 878
L + ++ ALYALQ + P +L FF YD E+I E+AF W+ E
Sbjct: 1500 LDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQN 1559
Query: 879 GKGKALFQVNQWLTWLETAEEEESE 903
GKG AL V + TWL AEEE +
Sbjct: 1560 GKGVALKSVTAFFTWLREAEEESED 1584
>gi|7661744 basic leucine zipper and W2 domains 2 [Homo sapiens]
Length = 419
Score = 52.4 bits (124), Expect = 2e-06
Identities = 91/431 (21%), Positives = 163/431 (37%), Gaps = 64/431 (14%)
Query: 520 KTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAV------NGVR-EMR 572
K P++ + KT K+ K E +T+V +G+ EAV G R + R
Sbjct: 3 KHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYR 62
Query: 573 APKHFLPEMLSKVIILSLDRS---DEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQC 629
L ++L +L+ + D DK K ++ E T N+ Q F ++ +
Sbjct: 63 RYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRY 122
Query: 630 PKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLC------------ 677
LE L F +E ++ L+ L P +L
Sbjct: 123 KYLEKAFEDEMKKLLLFLKAFSETEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGI 182
Query: 678 LQQLAKLQDREWLTELFQQS------KVNMQKMLPEI----DQNKDRMLEILEGKGLSFL 727
A + W+ E S K N+ K L E+ Q+ D + GL L
Sbjct: 183 AASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKEL 242
Query: 728 FPLLK----------LEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFL 777
L+ L+KEL +++ + + + ++K+ + + + +L T +
Sbjct: 243 SDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCIM 302
Query: 778 QYISSEVNPPSDETDSSSAPSKEQLEQEKQL--LLSFKPVMQKFLHDHVDLQVSALYALQ 835
+ KE+L E+ L L + P++ F ++ L +Q
Sbjct: 303 NAVEWN--------------KKEELVAEQALKHLKQYAPLLAVF-SSQGQSELILLQKVQ 347
Query: 836 VHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALF--QVNQWLTW 893
+CY++ + V FY +++ EEA L W + + KGK++F Q+ +++ W
Sbjct: 348 EYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYK---EAHVAKGKSVFLDQMKKFVEW 404
Query: 894 LETAEEEESEE 904
L+ AEEE E
Sbjct: 405 LQNAEEESESE 415
>gi|229577398 basic leucine zipper and W2 domains 2 [Homo sapiens]
Length = 419
Score = 52.4 bits (124), Expect = 2e-06
Identities = 91/431 (21%), Positives = 163/431 (37%), Gaps = 64/431 (14%)
Query: 520 KTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAV------NGVR-EMR 572
K P++ + KT K+ K E +T+V +G+ EAV G R + R
Sbjct: 3 KHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYR 62
Query: 573 APKHFLPEMLSKVIILSLDRS---DEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQC 629
L ++L +L+ + D DK K ++ E T N+ Q F ++ +
Sbjct: 63 RYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRY 122
Query: 630 PKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLC------------ 677
LE L F +E ++ L+ L P +L
Sbjct: 123 KYLEKAFEDEMKKLLLFLKAFSETEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGI 182
Query: 678 LQQLAKLQDREWLTELFQQS------KVNMQKMLPEI----DQNKDRMLEILEGKGLSFL 727
A + W+ E S K N+ K L E+ Q+ D + GL L
Sbjct: 183 AASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKEL 242
Query: 728 FPLLK----------LEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFL 777
L+ L+KEL +++ + + + ++K+ + + + +L T +
Sbjct: 243 SDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCIM 302
Query: 778 QYISSEVNPPSDETDSSSAPSKEQLEQEKQL--LLSFKPVMQKFLHDHVDLQVSALYALQ 835
+ KE+L E+ L L + P++ F ++ L +Q
Sbjct: 303 NAVEWN--------------KKEELVAEQALKHLKQYAPLLAVF-SSQGQSELILLQKVQ 347
Query: 836 VHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALF--QVNQWLTW 893
+CY++ + V FY +++ EEA L W + + KGK++F Q+ +++ W
Sbjct: 348 EYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYK---EAHVAKGKSVFLDQMKKFVEW 404
Query: 894 LETAEEEESEE 904
L+ AEEE E
Sbjct: 405 LQNAEEESESE 415
>gi|21735598 programmed cell death 4 isoform 2 [Homo sapiens]
Length = 458
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/119 (26%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Query: 540 SKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEK 599
S L+K + ++ EYL SG+ +EA + ++E+ P HF E++ + II+ L+ + E K
Sbjct: 312 SVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVP-HFHHELVYEAIIMVLESTGESTFK 370
Query: 600 -ASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVS 657
L+ L + T D + + + ++ P + +D+P S L +F + ++S
Sbjct: 371 MILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIIS 429
Score = 43.1 bits (100), Expect = 0.001
Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 11/118 (9%)
Query: 539 PSKEELLKLTET-VVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDK 597
P E + T T ++ EY G+ NE +R++ L EM S V +L++ + E K
Sbjct: 147 PLDERAFEKTLTPIIQEYFEHGDTNEVAEMLRDLN-----LGEMKSGVPVLAVSLALEGK 201
Query: 598 ----EKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAI 651
E S L+S L ++T+D ++F +L P+L +D P + QF ARA+
Sbjct: 202 ASHREMTSKLLSDLCGTVMSTTD-VEKSFDKLLKDLPELALDTPRAPQLVGQFIARAV 258
>gi|21735596 programmed cell death 4 isoform 1 [Homo sapiens]
Length = 469
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/119 (26%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Query: 540 SKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEK 599
S L+K + ++ EYL SG+ +EA + ++E+ P HF E++ + II+ L+ + E K
Sbjct: 323 SVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVP-HFHHELVYEAIIMVLESTGESTFK 381
Query: 600 -ASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVS 657
L+ L + T D + + + ++ P + +D+P S L +F + ++S
Sbjct: 382 MILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIIS 440
Score = 43.1 bits (100), Expect = 0.001
Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 11/118 (9%)
Query: 539 PSKEELLKLTET-VVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDK 597
P E + T T ++ EY G+ NE +R++ L EM S V +L++ + E K
Sbjct: 158 PLDERAFEKTLTPIIQEYFEHGDTNEVAEMLRDLN-----LGEMKSGVPVLAVSLALEGK 212
Query: 598 ----EKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAI 651
E S L+S L ++T+D ++F +L P+L +D P + QF ARA+
Sbjct: 213 ASHREMTSKLLSDLCGTVMSTTD-VEKSFDKLLKDLPELALDTPRAPQLVGQFIARAV 269
>gi|83267879 eukaryotic translation initiation factor 2B, subunit 5
epsilon, 82kDa [Homo sapiens]
Length = 721
Score = 44.7 bits (104), Expect = 4e-04
Identities = 38/153 (24%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Query: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815
DN+ +++ K NI + +Q +S V + S S LL ++ PV
Sbjct: 572 DNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPLLKAWSPV 631
Query: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQ 875
+ ++ D + AL A++ + + + FY +EI+ EE L+W +
Sbjct: 632 FRNYIKRAAD-HLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQ--R 688
Query: 876 EFPGKGKALF---QVNQWLTWLETAEEEESEEE 905
+ KG+ L Q+ +++ WL+ AEEE SE++
Sbjct: 689 DTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD 721
>gi|34452730 poly(A) binding protein interacting protein 1 isoform 3
[Homo sapiens]
Length = 367
Score = 42.7 bits (99), Expect = 0.002
Identities = 60/250 (24%), Positives = 108/250 (43%), Gaps = 37/250 (14%)
Query: 72 ERHDAIFRKVRGILNKLT--PEKFD---KLCLELLNVGVESKLILKGVILLIVDKALEEP 126
E + + V+ LN LT P F+ + E LN V + L+ ++ LI +A P
Sbjct: 41 EDYPTLSEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIP 100
Query: 127 KYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYD 186
+S + A+LC L+ QS FR+LL+ + + E+E + D
Sbjct: 101 NFSYMGARLCNYLSHHLTI-----------SPQSGNFRQLLLQRCRTEYEVK----DQAA 145
Query: 187 KRENPLLPEEEEQRAIAKIKMLG----NIKFIGELGKLDLIHESILHKCIKTLLEKKKRV 242
K + E +R A + LG N++ G G++ IL ++ LL +
Sbjct: 146 KGD-----EVTRKRFHAFVLFLGELYLNLEIKGTNGQVT--RADILQVGLRELLNA---L 195
Query: 243 QLKDMGEDLECLCQIMRTVGPRLDH---ERAKSLMDQYFARMCSLMLSKELPARIRFLLQ 299
M ++L C ++++ G L+ E+ K M++ R+ +++L ++ +L
Sbjct: 196 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 255
Query: 300 DTVELREHHW 309
VELR +W
Sbjct: 256 KLVELRSSNW 265
>gi|33386693 poly(A) binding protein interacting protein 1 isoform 2
[Homo sapiens]
Length = 400
Score = 42.7 bits (99), Expect = 0.002
Identities = 60/250 (24%), Positives = 108/250 (43%), Gaps = 37/250 (14%)
Query: 72 ERHDAIFRKVRGILNKLT--PEKFD---KLCLELLNVGVESKLILKGVILLIVDKALEEP 126
E + + V+ LN LT P F+ + E LN V + L+ ++ LI +A P
Sbjct: 74 EDYPTLSEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIP 133
Query: 127 KYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYD 186
+S + A+LC L+ QS FR+LL+ + + E+E + D
Sbjct: 134 NFSYMGARLCNYLSHHLTI-----------SPQSGNFRQLLLQRCRTEYEVK----DQAA 178
Query: 187 KRENPLLPEEEEQRAIAKIKMLG----NIKFIGELGKLDLIHESILHKCIKTLLEKKKRV 242
K + E +R A + LG N++ G G++ IL ++ LL +
Sbjct: 179 KGD-----EVTRKRFHAFVLFLGELYLNLEIKGTNGQVT--RADILQVGLRELLNA---L 228
Query: 243 QLKDMGEDLECLCQIMRTVGPRLDH---ERAKSLMDQYFARMCSLMLSKELPARIRFLLQ 299
M ++L C ++++ G L+ E+ K M++ R+ +++L ++ +L
Sbjct: 229 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 288
Query: 300 DTVELREHHW 309
VELR +W
Sbjct: 289 KLVELRSSNW 298
>gi|17511255 poly(A) binding protein interacting protein 1 isoform 1
[Homo sapiens]
Length = 479
Score = 42.7 bits (99), Expect = 0.002
Identities = 60/250 (24%), Positives = 108/250 (43%), Gaps = 37/250 (14%)
Query: 72 ERHDAIFRKVRGILNKLT--PEKFD---KLCLELLNVGVESKLILKGVILLIVDKALEEP 126
E + + V+ LN LT P F+ + E LN V + L+ ++ LI +A P
Sbjct: 153 EDYPTLSEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIP 212
Query: 127 KYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYD 186
+S + A+LC L+ QS FR+LL+ + + E+E + D
Sbjct: 213 NFSYMGARLCNYLSHHLTI-----------SPQSGNFRQLLLQRCRTEYEVK----DQAA 257
Query: 187 KRENPLLPEEEEQRAIAKIKMLG----NIKFIGELGKLDLIHESILHKCIKTLLEKKKRV 242
K + E +R A + LG N++ G G++ IL ++ LL +
Sbjct: 258 KGD-----EVTRKRFHAFVLFLGELYLNLEIKGTNGQVT--RADILQVGLRELLNA---L 307
Query: 243 QLKDMGEDLECLCQIMRTVGPRLDH---ERAKSLMDQYFARMCSLMLSKELPARIRFLLQ 299
M ++L C ++++ G L+ E+ K M++ R+ +++L ++ +L
Sbjct: 308 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 367
Query: 300 DTVELREHHW 309
VELR +W
Sbjct: 368 KLVELRSSNW 377
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 6/117 (5%)
Query: 428 KFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEI---SLRPAQSFLMNK 484
+ ++ Q Q Q Q Q Q Q + + + Q+ +I + PAQ + K
Sbjct: 2715 QLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGK 2774
Query: 485 ---NQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPP 538
+ K+Q Q +PP PP+ Q+ P T Q+ ++T+ P Q+ P T+ P
Sbjct: 2775 LTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAP 2831
>gi|41281429 basic leucine zipper and W2 domains 1 [Homo sapiens]
Length = 353
Score = 41.2 bits (95), Expect = 0.004
Identities = 24/60 (40%), Positives = 36/60 (60%), Gaps = 6/60 (10%)
Query: 850 RFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALF--QVNQWLTWLETAEEEESEEEAD 907
+ V FY E++ EE L W +D KGK++F Q+ +++ WL+ A EEESE EA+
Sbjct: 295 KIVVLFYKAEVLSEEPILKWYKDA---HVAKGKSVFLEQMKKFVEWLKNA-EEESESEAE 350
>gi|7662112 hypothetical protein LOC9811 isoform 1 [Homo sapiens]
Length = 598
Score = 40.8 bits (94), Expect = 0.006
Identities = 60/271 (22%), Positives = 104/271 (38%), Gaps = 55/271 (20%)
Query: 54 RSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFD---KLC--LELLNVGVESK 108
R + D A + ++ + D + ILN + D KL +E S+
Sbjct: 352 RRLKEKDEVAVETTTPQQNKMDKLIE----ILNSMRNNSSDVDTKLTTFMEEAQNSTNSE 407
Query: 109 LILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLI 168
+L ++ I KA+ + ++ A+LC ++A + T FR LL+
Sbjct: 408 EMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALF--------------MVEGTKFRSLLL 453
Query: 169 SKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGEL--------GKL 220
+ LQ +F R EE +Q+ + + LG I F+ E+ G+
Sbjct: 454 NMLQKDFTVR----------------EELQQQDVER--WLGFITFLCEVFGTMRSSTGEP 495
Query: 221 DLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFAR 280
+ ++ C++ LL Q +D+ ED C + RL E+ +M + A
Sbjct: 496 FRVLVCPIYTCLRELL------QSQDVKEDAVLCCSMELQSTGRLLEEQLPEMMTELLAS 549
Query: 281 MCSLMLSKELPARIRFLLQDTVELREHHWVP 311
ML R LL + +EL + W P
Sbjct: 550 ARDKMLCPSESMLTRSLLLEVIELHANSWNP 580
>gi|169212085 PREDICTED: similar to poly(A) binding protein
interacting protein 1 [Homo sapiens]
Length = 516
Score = 40.0 bits (92), Expect = 0.010
Identities = 59/241 (24%), Positives = 104/241 (43%), Gaps = 37/241 (15%)
Query: 81 VRGILNKLT--PEKFD---KLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQL 135
V+ LN LT P F+ + E LN V + L+ + LI +A P +S + A+L
Sbjct: 199 VQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELAELIYQQATSIPNFSYMGARL 258
Query: 136 CLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPE 195
C L+ QS FR+LL+ + + E+E + D K + E
Sbjct: 259 CNYLSHHLTI-----------SPQSGNFRQLLLQRCRTEYEVK----DQAAKGD-----E 298
Query: 196 EEEQRAIAKIKMLG----NIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDL 251
+R A + LG N++ G G++ IL ++ LL + M ++L
Sbjct: 299 VTRKRFHAFVFFLGELYLNLEIKGTNGQVT--RADILQVGLRELLNA---LFSNPMDDNL 353
Query: 252 ECLCQIMRTVGPRLDH---ERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHH 308
C ++++ G L+ E+ K M++ R+ +++L ++ +L VELR +
Sbjct: 354 ICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSN 413
Query: 309 W 309
W
Sbjct: 414 W 414
>gi|239752553 PREDICTED: similar to poly(A) binding protein
interacting protein 1 [Homo sapiens]
Length = 457
Score = 40.0 bits (92), Expect = 0.010
Identities = 59/241 (24%), Positives = 104/241 (43%), Gaps = 37/241 (15%)
Query: 81 VRGILNKLT--PEKFD---KLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQL 135
V+ LN LT P F+ + E LN V + L+ + LI +A P +S + A+L
Sbjct: 140 VQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELAELIYQQATSIPNFSYMGARL 199
Query: 136 CLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPE 195
C L+ QS FR+LL+ + + E+E + D K + E
Sbjct: 200 CNYLSHHLTI-----------SPQSGNFRQLLLQRCRTEYEVK----DQAAKGD-----E 239
Query: 196 EEEQRAIAKIKMLG----NIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDL 251
+R A + LG N++ G G++ IL ++ LL + M ++L
Sbjct: 240 VTRKRFHAFVFFLGELYLNLEIKGTNGQVT--RADILQVGLRELLNA---LFSNPMDDNL 294
Query: 252 ECLCQIMRTVGPRLDH---ERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHH 308
C ++++ G L+ E+ K M++ R+ +++L ++ +L VELR +
Sbjct: 295 ICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSN 354
Query: 309 W 309
W
Sbjct: 355 W 355
>gi|89041275 PREDICTED: similar to poly(A) binding protein
interacting protein 1 [Homo sapiens]
Length = 488
Score = 40.0 bits (92), Expect = 0.010
Identities = 59/241 (24%), Positives = 104/241 (43%), Gaps = 37/241 (15%)
Query: 81 VRGILNKLT--PEKFD---KLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQL 135
V+ LN LT P F+ + E LN V + L+ + LI +A P +S + A+L
Sbjct: 171 VQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELAELIYQQATSIPNFSYMGARL 230
Query: 136 CLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPE 195
C L+ QS FR+LL+ + + E+E + D K + E
Sbjct: 231 CNYLSHHLTI-----------SPQSGNFRQLLLQRCRTEYEVK----DQAAKGD-----E 270
Query: 196 EEEQRAIAKIKMLG----NIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDL 251
+R A + LG N++ G G++ IL ++ LL + M ++L
Sbjct: 271 VTRKRFHAFVFFLGELYLNLEIKGTNGQVT--RADILQVGLRELLNA---LFSNPMDDNL 325
Query: 252 ECLCQIMRTVGPRLDH---ERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHH 308
C ++++ G L+ E+ K M++ R+ +++L ++ +L VELR +
Sbjct: 326 ICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSN 385
Query: 309 W 309
W
Sbjct: 386 W 386
>gi|215422401 hypothetical protein LOC9811 isoform 2 [Homo sapiens]
Length = 600
Score = 39.3 bits (90), Expect = 0.017
Identities = 49/213 (23%), Positives = 85/213 (39%), Gaps = 46/213 (21%)
Query: 107 SKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRL 166
S+ +L ++ I KA+ + ++ A+LC ++A + T FR L
Sbjct: 408 SEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALF--------------MVEGTKFRSL 453
Query: 167 LISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGEL--------G 218
L++ LQ +F R EE +Q+ + + LG I F+ E+ G
Sbjct: 454 LLNMLQKDFTVR----------------EELQQQDVER--WLGFITFLCEVFGTMRSSTG 495
Query: 219 KLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYF 278
+ + ++ C++ LL Q +D+ ED C + RL E+ +M +
Sbjct: 496 EPFRVLVCPIYTCLRELL------QSQDVKEDAVLCCSMELQSTGRLLEEQLPEMMTELL 549
Query: 279 ARMCSLMLSKELPARIRFLLQDTVELREHHWVP 311
A ML R LL + +EL + W P
Sbjct: 550 ASARDKMLCPSESMLTRSLLLEVIELHANSWNP 582
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 38.1 bits (87), Expect = 0.037
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 7/68 (10%)
Query: 476 PAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAK--T 533
P QS +++ VP L I PS P RT PP Q+ + + PL Q+ PA+
Sbjct: 1050 PCQSPTISEGPVPSLP-----IRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLE 1104
Query: 534 SKKPPPSK 541
K+PPP +
Sbjct: 1105 PKRPPPPR 1112
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 38.1 bits (87), Expect = 0.037
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 7/68 (10%)
Query: 476 PAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAK--T 533
P QS +++ VP L I PS P RT PP Q+ + + PL Q+ PA+
Sbjct: 1089 PCQSPTISEGPVPSLP-----IRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLE 1143
Query: 534 SKKPPPSK 541
K+PPP +
Sbjct: 1144 PKRPPPPR 1151
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 38.1 bits (87), Expect = 0.037
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 7/68 (10%)
Query: 476 PAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAK--T 533
P QS +++ VP L I PS P RT PP Q+ + + PL Q+ PA+
Sbjct: 1089 PCQSPTISEGPVPSLP-----IRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLE 1143
Query: 534 SKKPPPSK 541
K+PPP +
Sbjct: 1144 PKRPPPPR 1151
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 38.1 bits (87), Expect = 0.037
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 7/68 (10%)
Query: 476 PAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAK--T 533
P QS +++ VP L I PS P RT PP Q+ + + PL Q+ PA+
Sbjct: 1045 PCQSPTISEGPVPSLP-----IRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLE 1099
Query: 534 SKKPPPSK 541
K+PPP +
Sbjct: 1100 PKRPPPPR 1107
>gi|50428940 mediator complex subunit 25 [Homo sapiens]
Length = 747
Score = 38.1 bits (87), Expect = 0.037
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 10/92 (10%)
Query: 457 MPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQ 516
+PP++ G L+A +++ + A KNQ L P+ + I P Q PP Q P
Sbjct: 268 VPPQYQVPGNLSAAQVAAQNAVEAA--KNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPA 325
Query: 517 LGLKTNPPLIQEKPAKTSKKPPPSKEELLKLT 548
L PP + KPPP+ + L T
Sbjct: 326 PQLPPGPP--------GAPKPPPASQPSLVST 349
Score = 31.2 bits (69), Expect = 4.6
Identities = 46/172 (26%), Positives = 63/172 (36%), Gaps = 43/172 (25%)
Query: 400 RHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQ--------GLLSQLQ 451
+ + Q G GG PP E + SQ L QL Q Q G Q Q
Sbjct: 549 QQKLEQQQRGMGGQQAPPGLGPILEDQAR--PSQNLLQLRPPQPQPQGTVGASGATGQPQ 606
Query: 452 GQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPP- 510
Q PP + +G A + P + + Q P PQ+ + + PP+T PP
Sbjct: 607 PQGTAQPPPGAPQGPPGA---ASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPP 663
Query: 511 ----------------------LGQTPQLGLKTNPPLIQEKPAKT--SKKPP 538
LGQ PQLG PPL+ PA++ ++ PP
Sbjct: 664 QASLHHLQPPGAPALLPPPHQGLGQ-PQLG----PPLLHPPPAQSWPAQLPP 710
>gi|21361337 eukaryotic translation initiation factor 5 [Homo
sapiens]
Length = 431
Score = 37.7 bits (86), Expect = 0.049
Identities = 26/114 (22%), Positives = 55/114 (48%), Gaps = 11/114 (9%)
Query: 803 EQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRF---FVHFYDME 859
E+ ++ + ++ +F H++ Q L+ L+ C + ++ + YD +
Sbjct: 287 EKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLE--CVVAMHQAQLISKIPHILKEMYDAD 344
Query: 860 IIEEEAFLAWKEDITQEFPGKGKA---LFQVNQWLTWLETAEEEES---EEEAD 907
++EEE ++W E ++++ K A + ++ WL+ AEEE S EE+ D
Sbjct: 345 LLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDED 398
>gi|37537716 eukaryotic translation initiation factor 5 [Homo
sapiens]
Length = 431
Score = 37.7 bits (86), Expect = 0.049
Identities = 26/114 (22%), Positives = 55/114 (48%), Gaps = 11/114 (9%)
Query: 803 EQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRF---FVHFYDME 859
E+ ++ + ++ +F H++ Q L+ L+ C + ++ + YD +
Sbjct: 287 EKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLE--CVVAMHQAQLISKIPHILKEMYDAD 344
Query: 860 IIEEEAFLAWKEDITQEFPGKGKA---LFQVNQWLTWLETAEEEES---EEEAD 907
++EEE ++W E ++++ K A + ++ WL+ AEEE S EE+ D
Sbjct: 345 LLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDED 398
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,886,602
Number of Sequences: 37866
Number of extensions: 1828966
Number of successful extensions: 8976
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 140
Number of HSP's that attempted gapping in prelim test: 8307
Number of HSP's gapped (non-prelim): 670
length of query: 907
length of database: 18,247,518
effective HSP length: 111
effective length of query: 796
effective length of database: 14,044,392
effective search space: 11179336032
effective search space used: 11179336032
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.