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Search of human proteins with 4503285
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503285 aldo-keto reductase family 1, member C2 [Homo
sapiens]
(323 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] 659 0.0
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] 659 0.0
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] 644 0.0
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens] 579 e-165
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] 548 e-156
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens] 395 e-110
gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens] 320 8e-88
gi|223468663 aldo-keto reductase family 1, member B10 [Homo sapi... 307 9e-84
gi|122937516 aldo-keto reductase family 1, member B10-like [Homo... 294 8e-80
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens] 270 1e-72
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens] 270 1e-72
gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo ... 270 2e-72
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens] 251 8e-67
gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s... 54 2e-07
gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s... 54 2e-07
gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens] 52 5e-07
gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens] 49 6e-06
gi|27436964 potassium voltage-gated channel, shaker-related subf... 42 7e-04
gi|27436962 potassium voltage-gated channel, shaker-related subf... 42 7e-04
gi|27436966 potassium voltage-gated channel, shaker-related subf... 42 7e-04
gi|4504825 potassium voltage-gated channel, shaker-related subfa... 38 0.011
gi|27436969 potassium voltage-gated channel, shaker-related subf... 38 0.011
gi|27436971 potassium voltage-gated channel, shaker-related subf... 35 0.12
gi|4503503 eukaryotic translation initiation factor 2B, subunit ... 31 1.7
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 30 2.9
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s... 29 4.9
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap... 29 4.9
>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 659 bits (1700), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
Sbjct: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
RNVRYLTLDIFAGPPNYPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 659 bits (1700), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
Sbjct: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
RNVRYLTLDIFAGPPNYPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
Length = 323
Score = 644 bits (1662), Expect = 0.0
Identities = 316/323 (97%), Positives = 318/323 (98%)
Query: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEA KLAIEAGF HIDSAH+YNNEEQ
Sbjct: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
VGLAIRSKIADGSVKREDIFYTSKLW NSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
SVKPGEEVIPKDENGKILFDTVDLCATWEA+EKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
RNVRYLTLDIFAGPPNYPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
Length = 323
Score = 579 bits (1492), Expect = e-165
Identities = 281/323 (86%), Positives = 297/323 (91%)
Query: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
MDSK+QCVKLNDGHFMPVLGFGTYAP EVP+SKALE KLAIEAGF HIDSAH+YNNEEQ
Sbjct: 1 MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
VGLAIRSKIADGSVKREDIFYTSKLWS HRPELVRPALE SLK QLDYVDLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
S+KPGEE+ P DENGK++FD VDLC TWEAMEKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
GLKYKPVCNQVECHPYFN+ KLLDFCKSKDIVLVAYSALGS R++ WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT+E+MKAIDGL+
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300
Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
RN+ Y D FA PNYP+SDEY
Sbjct: 301 RNLHYFNSDSFASHPNYPYSDEY 323
>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
Length = 323
Score = 548 bits (1412), Expect = e-156
Identities = 263/323 (81%), Positives = 292/323 (90%)
Query: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
MD KYQ V+LNDGHFMPVLGFGTYAP EVP+++A+E KLAIEAGF HIDSA++YNNEEQ
Sbjct: 1 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
VGLAIRSKIADGSVKREDIFYTSKLW +P++V+PALE SLK LQLDYVDLYL+HFP+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
++KPGE +PKDENGK++FDTVDL ATWE MEKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
GLKYKPVCNQVECHPY NQ KLLDFCKSKDIVLVA+SALG+ R + WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
LCALAKKHK+TPALIALRYQLQRGVVVLAKSYNEQRIR+N+QVFEFQLTSE+MK +DGLN
Sbjct: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300
Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
RN RY+ +D P+YPFSDEY
Sbjct: 301 RNYRYVVMDFLMDHPDYPFSDEY 323
>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
Length = 326
Score = 395 bits (1014), Expect = e-110
Identities = 185/317 (58%), Positives = 243/317 (76%), Gaps = 1/317 (0%)
Query: 8 VKLNDGHFMPVLGFGTYA-PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIR 66
+ L+DG+ +P++G GTY+ P PK +VK+AI+ G+ HID A++Y NE +VG AIR
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 67 SKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
KIA+G V+REDIFY KLW+ +H PE+VRP LER+L+ LQLDYVDLY+I P++ KPG+
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 127 EVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKP 186
E+ P+DENGK L+ +LCATWEAME CKDAGL KS+GVSNFN R LE+ILNKPGLK+KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAK 246
V NQVECHPYF Q KLL FC+ DIV+ AYS LG+ R WV+ +SP LL+D +L +L K
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249
Query: 247 KHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYL 306
++ +T A I LR+ +QRGVVV+ KS+N +RI++N Q+F+F LT EEMK I+ LN+NVR++
Sbjct: 250 RYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFV 309
Query: 307 TLDIFAGPPNYPFSDEY 323
L ++ P YPF DEY
Sbjct: 310 ELLMWRDHPEYPFHDEY 326
>gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]
Length = 316
Score = 320 bits (821), Expect = 8e-88
Identities = 154/314 (49%), Positives = 214/314 (68%), Gaps = 4/314 (1%)
Query: 10 LNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKI 69
LN+G MP+LG GT+ + P + EAVK+AI+ G+ HID AHVY NE +VG+AI+ K+
Sbjct: 7 LNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63
Query: 70 ADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI 129
+ VKRE++F SKLW H LV+ A +++L +L+LDY+DLYLIH+P KPG+E
Sbjct: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123
Query: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCN 189
P DE+G ++ ++ TW AME+ D GL K+IG+SNFNH +EMILNKPGLKYKP N
Sbjct: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183
Query: 190 QVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHK 249
Q+ECHPY Q KL+ +C+SK IV+ AYS LGS + PW P P LLEDP + A+A KH
Sbjct: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHN 242
Query: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD 309
+T A + +R+ +QR +VV+ KS +RI +N +VF+F+L+S++M + NRN R L
Sbjct: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302
Query: 310 IFAGPPNYPFSDEY 323
+YPF +E+
Sbjct: 303 SCTSHKDYPFHEEF 316
>gi|223468663 aldo-keto reductase family 1, member B10 [Homo
sapiens]
Length = 316
Score = 307 bits (786), Expect = 9e-84
Identities = 154/316 (48%), Positives = 209/316 (66%), Gaps = 4/316 (1%)
Query: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
V+L+ MP++G GT+ + P K EAVK+AI+AG+ HID A+VY NE +VG AI+
Sbjct: 5 VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61
Query: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
KI + +VKRED+F SKLW LVR A E++LK+L+L Y+D+YLIH+P K G++
Sbjct: 62 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121
Query: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
+ PKD+ G + WEAME+ D GL K++GVSNF+H +E +LNKPGLKYKPV
Sbjct: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181
Query: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
NQVECHPY Q KL+ +C SK I + AYS LGS + PW P P LLEDP + +A K
Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAK 240
Query: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLT 307
HK+T A + +R+ +QR V+V+ KS RI +N+QVF+F+L+ EEM I NRN R
Sbjct: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300
Query: 308 LDIFAGPPNYPFSDEY 323
+ + +YPF+ EY
Sbjct: 301 VLQSSHLEDYPFNAEY 316
>gi|122937516 aldo-keto reductase family 1, member B10-like [Homo
sapiens]
Length = 316
Score = 294 bits (752), Expect = 8e-80
Identities = 148/316 (46%), Positives = 201/316 (63%), Gaps = 4/316 (1%)
Query: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
V+L+ MP++G GT+ K EAVK+AI+A + HID A+ Y N+ +VG AI+
Sbjct: 5 VELSTKAKMPIVGLGTWRSL---LGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQE 61
Query: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
KI + +V RED+F SK+W LVR A E++LK+L+L Y+D+YLIH+P K G++
Sbjct: 62 KIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDD 121
Query: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
PKD+ G ++ WEAME+ D GL K++GVSNFNH +E +LNKPGLKYKPV
Sbjct: 122 FFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPV 181
Query: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
NQVECHPY Q KL+ +C SK I + AYS LGS + PW P P LLEDP + +A K
Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAK 240
Query: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLT 307
HK+T A + +R+ +QR V V+ KS I +N+QVF+F+L+ EEM I NRN R
Sbjct: 241 HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD 300
Query: 308 LDIFAGPPNYPFSDEY 323
F+ ++PF EY
Sbjct: 301 FKEFSHLEDFPFDAEY 316
>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
Length = 325
Score = 270 bits (691), Expect = 1e-72
Identities = 144/327 (44%), Positives = 214/327 (65%), Gaps = 16/327 (4%)
Query: 7 CVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIR 66
CV L+ G MP++G GT+ +E + KA AVK A+ G+ HID A +Y NE ++G A++
Sbjct: 5 CVLLHTGQKMPLIGLGTWK-SEPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 67 SKIADG-SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
+ G +V RE++F TSKLW+ H PE V PAL ++L +LQL+Y+DLYL+H+P + + G
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
+ PK+ +G I +D+ TW+A+E GL +++G+SNFN R ++ IL+ + +
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179
Query: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALA 245
P QVECHPY Q +L+ C+++ + + AYS LGS + W DP+ PVLLE+PV+ ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS-SDRAWRDPDEPVLLEEPVVLALA 238
Query: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRY 305
+K+ R+PA I LR+Q+QR V+ + KS RI QN++VF+F + EEMK ++ LN+N RY
Sbjct: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298
Query: 306 ----LTLD-----IFAGPPNYPFSDEY 323
LT+D AG P YPF+D Y
Sbjct: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325
>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
Length = 325
Score = 270 bits (691), Expect = 1e-72
Identities = 144/327 (44%), Positives = 214/327 (65%), Gaps = 16/327 (4%)
Query: 7 CVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIR 66
CV L+ G MP++G GT+ +E + KA AVK A+ G+ HID A +Y NE ++G A++
Sbjct: 5 CVLLHTGQKMPLIGLGTWK-SEPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 67 SKIADG-SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
+ G +V RE++F TSKLW+ H PE V PAL ++L +LQL+Y+DLYL+H+P + + G
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
+ PK+ +G I +D+ TW+A+E GL +++G+SNFN R ++ IL+ + +
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179
Query: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALA 245
P QVECHPY Q +L+ C+++ + + AYS LGS + W DP+ PVLLE+PV+ ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS-SDRAWRDPDEPVLLEEPVVLALA 238
Query: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRY 305
+K+ R+PA I LR+Q+QR V+ + KS RI QN++VF+F + EEMK ++ LN+N RY
Sbjct: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298
Query: 306 ----LTLD-----IFAGPPNYPFSDEY 323
LT+D AG P YPF+D Y
Sbjct: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325
>gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo
sapiens]
Length = 320
Score = 270 bits (689), Expect = 2e-72
Identities = 139/327 (42%), Positives = 199/327 (60%), Gaps = 29/327 (8%)
Query: 16 MPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVK 75
+P +G ++ + K EAVK AI+AG+ H D A+ Y+NE +VG IR KI +G+V+
Sbjct: 4 IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
Query: 76 REDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE--------- 126
RED+F +KLW H+ LV A +SLK L+L+Y+DLYLIH+P+ KP
Sbjct: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120
Query: 127 ----------EVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMI 176
+ +P DE+ ++ D TWEAME GL K+IGVSNFNH LE +
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180
Query: 177 LNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLL 236
LNKPGL++KP+ NQ+ECHPY Q+ L+ FC+S+D+ + AY LG E VD L+
Sbjct: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE--GVD-----LI 233
Query: 237 EDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAI 296
++PV+ +AK+H ++PA I +R+Q+QR V+V+ S I++N+QVF+F+LT +M I
Sbjct: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293
Query: 297 DGLNRNVRYLTLDIFAGPPNYPFSDEY 323
LNRN+R I +YPF EY
Sbjct: 294 LSLNRNLRLAMFPITKNHKDYPFHIEY 320
>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
Length = 139
Score = 251 bits (640), Expect = 8e-67
Identities = 123/123 (100%), Positives = 123/123 (100%)
Query: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
Sbjct: 1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 121 SVK 123
SVK
Sbjct: 121 SVK 123
>gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
sapiens]
Length = 249
Score = 53.5 bits (127), Expect = 2e-07
Identities = 48/146 (32%), Positives = 68/146 (46%), Gaps = 17/146 (11%)
Query: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
+ P S A+ + +E G ID+A +Y++ + GL +R +D VK I +
Sbjct: 24 DAPTSAAV--TRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78
Query: 84 KLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKIL 138
W NS +P+ VR LE SLK LQ VDL+ +H P P EE + + GK +
Sbjct: 79 NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138
Query: 139 FDTVDLCATWEAMEKCKDAGLAKSIG 164
+ A WE E C L KS G
Sbjct: 139 ELGLSNYAAWEVAEICT---LCKSNG 161
>gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo
sapiens]
Length = 331
Score = 53.5 bits (127), Expect = 2e-07
Identities = 48/146 (32%), Positives = 68/146 (46%), Gaps = 17/146 (11%)
Query: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
+ P S A+ + +E G ID+A +Y++ + GL +R +D VK I +
Sbjct: 24 DAPTSAAV--TRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78
Query: 84 KLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKIL 138
W NS +P+ VR LE SLK LQ VDL+ +H P P EE + + GK +
Sbjct: 79 NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138
Query: 139 FDTVDLCATWEAMEKCKDAGLAKSIG 164
+ A WE E C L KS G
Sbjct: 139 ELGLSNYAAWEVAEICT---LCKSNG 161
>gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]
Length = 331
Score = 52.4 bits (124), Expect = 5e-07
Identities = 47/145 (32%), Positives = 67/145 (46%), Gaps = 15/145 (10%)
Query: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
+ P S A+ + +E G ID+A VY+ + GL +R +D VK +
Sbjct: 24 DAPTSAAV--TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79
Query: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKILF 139
L+ NS +P+ +R LE SLK LQ VDL+ +H P P EE + + GK +
Sbjct: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139
Query: 140 DTVDLCATWEAMEKCKDAGLAKSIG 164
+ A WE E C L KS G
Sbjct: 140 LGLSNYAAWEVAEICT---LCKSNG 161
>gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]
Length = 359
Score = 48.9 bits (115), Expect = 6e-06
Identities = 47/146 (32%), Positives = 67/146 (45%), Gaps = 17/146 (11%)
Query: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
+ P S A AV+ +E G +D+A +Y++ + GL + D VK I +
Sbjct: 52 DAPASAA--AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKA 106
Query: 84 KLWSN-SHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPK----DENGKIL 138
W S +P+ VR LE SLK LQ VDL+ +H P P EE + + GK +
Sbjct: 107 NPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFV 166
Query: 139 FDTVDLCATWEAMEKCKDAGLAKSIG 164
+ A+WE E C L KS G
Sbjct: 167 ELGLSNYASWEVAEICT---LCKSNG 189
>gi|27436964 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 3 [Homo sapiens]
Length = 401
Score = 42.0 bits (97), Expect = 7e-04
Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%)
Query: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
LG GT+ ++ A + +A E+G + D+A VY E +G I+ K
Sbjct: 86 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141
Query: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
+R + T+KL W E + L+ SL+ LQL+YVD+ + P S P E
Sbjct: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 201
Query: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
E++ ++ + + T + W AME + +A+ +
Sbjct: 202 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 241
Query: 182 LKYKPVCNQVECHPYFNQR 200
PVC Q E H + ++
Sbjct: 242 --IPPVCEQAEYHLFQREK 258
>gi|27436962 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 2 [Homo sapiens]
Length = 408
Score = 42.0 bits (97), Expect = 7e-04
Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%)
Query: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
LG GT+ ++ A + +A E+G + D+A VY E +G I+ K
Sbjct: 93 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148
Query: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
+R + T+KL W E + L+ SL+ LQL+YVD+ + P S P E
Sbjct: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 208
Query: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
E++ ++ + + T + W AME + +A+ +
Sbjct: 209 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 248
Query: 182 LKYKPVCNQVECHPYFNQR 200
PVC Q E H + ++
Sbjct: 249 --IPPVCEQAEYHLFQREK 265
>gi|27436966 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 1 [Homo sapiens]
Length = 419
Score = 42.0 bits (97), Expect = 7e-04
Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%)
Query: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
LG GT+ ++ A + +A E+G + D+A VY E +G I+ K
Sbjct: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159
Query: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
+R + T+KL W E + L+ SL+ LQL+YVD+ + P S P E
Sbjct: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 219
Query: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
E++ ++ + + T + W AME + +A+ +
Sbjct: 220 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 259
Query: 182 LKYKPVCNQVECHPYFNQR 200
PVC Q E H + ++
Sbjct: 260 --IPPVCEQAEYHLFQREK 276
>gi|4504825 potassium voltage-gated channel, shaker-related
subfamily, beta member 2 isoform 1 [Homo sapiens]
Length = 367
Score = 38.1 bits (87), Expect = 0.011
Identities = 44/199 (22%), Positives = 80/199 (40%), Gaps = 43/199 (21%)
Query: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
LG GT+ ++ A + + LA + G + D+A VY E +G I+ K
Sbjct: 52 LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----G 107
Query: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
+R + T+K+ W E + L+ SL+ LQL+YVD+ + P P E
Sbjct: 108 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPME 167
Query: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
E + ++ + + T + W +ME + +A+ ++
Sbjct: 168 ETVRAMTHVINQGMAMYWGT----SRWSSMEIMEAYSVARQFNLT--------------- 208
Query: 182 LKYKPVCNQVECHPYFNQR 200
P+C Q E H + ++
Sbjct: 209 ---PPICEQAEYHMFQREK 224
>gi|27436969 potassium voltage-gated channel, shaker-related
subfamily, beta member 2 isoform 2 [Homo sapiens]
Length = 353
Score = 38.1 bits (87), Expect = 0.011
Identities = 44/199 (22%), Positives = 80/199 (40%), Gaps = 43/199 (21%)
Query: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
LG GT+ ++ A + + LA + G + D+A VY E +G I+ K
Sbjct: 38 LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----G 93
Query: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
+R + T+K+ W E + L+ SL+ LQL+YVD+ + P P E
Sbjct: 94 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPME 153
Query: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
E + ++ + + T + W +ME + +A+ ++
Sbjct: 154 ETVRAMTHVINQGMAMYWGT----SRWSSMEIMEAYSVARQFNLT--------------- 194
Query: 182 LKYKPVCNQVECHPYFNQR 200
P+C Q E H + ++
Sbjct: 195 ---PPICEQAEYHMFQREK 210
>gi|27436971 potassium voltage-gated channel, shaker-related
subfamily, beta member 3 [Homo sapiens]
Length = 404
Score = 34.7 bits (78), Expect = 0.12
Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 16/123 (13%)
Query: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
LG GT+ +++ A + + +A E G + D+A VY E +G ++SK
Sbjct: 93 LGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK----G 148
Query: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
+R T+K+ W E + L SL+ LQL YVD+ + P E
Sbjct: 149 WRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPME 208
Query: 127 EVI 129
E++
Sbjct: 209 EIV 211
>gi|4503503 eukaryotic translation initiation factor 2B, subunit 1
alpha, 26kDa [Homo sapiens]
Length = 305
Score = 30.8 bits (68), Expect = 1.7
Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 15/76 (19%)
Query: 176 ILNKPGLKYKPVCNQVECHPYF--------------NQRKLLDFCKSK-DIVLVAYSALG 220
I+NK G VC + + P++ NQ+ + D K K D + VA +
Sbjct: 206 IINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQD 265
Query: 221 SHREEPWVDPNSPVLL 236
E PWVD +P L+
Sbjct: 266 LKEEHPWVDYTAPSLI 281
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 30.0 bits (66), Expect = 2.9
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Query: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
R+ + SV+ ED F+ +++S EL+ P E + + +DL L+ + KP
Sbjct: 673 RTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLL-TRIPGKPY 731
Query: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
+E P K + + A +A EK + G K
Sbjct: 732 KETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRK 767
>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 29.3 bits (64), Expect = 4.9
Identities = 15/38 (39%), Positives = 20/38 (52%)
Query: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSN 167
P N K LF V+ T +E CK+AG+ K I S+
Sbjct: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145
>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 29.3 bits (64), Expect = 4.9
Identities = 15/38 (39%), Positives = 20/38 (52%)
Query: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSN 167
P N K LF V+ T +E CK+AG+ K I S+
Sbjct: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,803,972
Number of Sequences: 37866
Number of extensions: 549022
Number of successful extensions: 1096
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1057
Number of HSP's gapped (non-prelim): 27
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.