Guide to the Human Genome
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Search of human proteins with 4503285

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503285 aldo-keto reductase family 1, member C2 [Homo
sapiens]
         (323 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]    659   0.0  
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]     659   0.0  
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]     644   0.0  
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]    579   e-165
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]    548   e-156
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]     395   e-110
gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]     320   8e-88
gi|223468663 aldo-keto reductase family 1, member B10 [Homo sapi...   307   9e-84
gi|122937516 aldo-keto reductase family 1, member B10-like [Homo...   294   8e-80
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]    270   1e-72
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]     270   1e-72
gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo ...   270   2e-72
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]         251   8e-67
gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s...    54   2e-07
gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s...    54   2e-07
gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]     52   5e-07
gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]     49   6e-06
gi|27436964 potassium voltage-gated channel, shaker-related subf...    42   7e-04
gi|27436962 potassium voltage-gated channel, shaker-related subf...    42   7e-04
gi|27436966 potassium voltage-gated channel, shaker-related subf...    42   7e-04
gi|4504825 potassium voltage-gated channel, shaker-related subfa...    38   0.011
gi|27436969 potassium voltage-gated channel, shaker-related subf...    38   0.011
gi|27436971 potassium voltage-gated channel, shaker-related subf...    35   0.12 
gi|4503503 eukaryotic translation initiation factor 2B, subunit ...    31   1.7  
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    30   2.9  
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s...    29   4.9  
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap...    29   4.9  

>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  659 bits (1700), Expect = 0.0
 Identities = 323/323 (100%), Positives = 323/323 (100%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
           MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
           SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
           RNVRYLTLDIFAGPPNYPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  659 bits (1700), Expect = 0.0
 Identities = 323/323 (100%), Positives = 323/323 (100%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
           MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
           SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
           RNVRYLTLDIFAGPPNYPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
          Length = 323

 Score =  644 bits (1662), Expect = 0.0
 Identities = 316/323 (97%), Positives = 318/323 (98%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
           MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEA KLAIEAGF HIDSAH+YNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLW NSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
           SVKPGEEVIPKDENGKILFDTVDLCATWEA+EKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
           RNVRYLTLDIFAGPPNYPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
          Length = 323

 Score =  579 bits (1492), Expect = e-165
 Identities = 281/323 (86%), Positives = 297/323 (91%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
           MDSK+QCVKLNDGHFMPVLGFGTYAP EVP+SKALE  KLAIEAGF HIDSAH+YNNEEQ
Sbjct: 1   MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLWS  HRPELVRPALE SLK  QLDYVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
           S+KPGEE+ P DENGK++FD VDLC TWEAMEKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFN+ KLLDFCKSKDIVLVAYSALGS R++ WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT+E+MKAIDGL+
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
           RN+ Y   D FA  PNYP+SDEY
Sbjct: 301 RNLHYFNSDSFASHPNYPYSDEY 323


>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
          Length = 323

 Score =  548 bits (1412), Expect = e-156
 Identities = 263/323 (81%), Positives = 292/323 (90%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
           MD KYQ V+LNDGHFMPVLGFGTYAP EVP+++A+E  KLAIEAGF HIDSA++YNNEEQ
Sbjct: 1   MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLW    +P++V+PALE SLK LQLDYVDLYL+HFP+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120

Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
           ++KPGE  +PKDENGK++FDTVDL ATWE MEKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPY NQ KLLDFCKSKDIVLVA+SALG+ R + WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
           LCALAKKHK+TPALIALRYQLQRGVVVLAKSYNEQRIR+N+QVFEFQLTSE+MK +DGLN
Sbjct: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300

Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
           RN RY+ +D     P+YPFSDEY
Sbjct: 301 RNYRYVVMDFLMDHPDYPFSDEY 323


>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
          Length = 326

 Score =  395 bits (1014), Expect = e-110
 Identities = 185/317 (58%), Positives = 243/317 (76%), Gaps = 1/317 (0%)

Query: 8   VKLNDGHFMPVLGFGTYA-PAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIR 66
           + L+DG+ +P++G GTY+ P   PK     +VK+AI+ G+ HID A++Y NE +VG AIR
Sbjct: 10  IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69

Query: 67  SKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            KIA+G V+REDIFY  KLW+ +H PE+VRP LER+L+ LQLDYVDLY+I  P++ KPG+
Sbjct: 70  EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129

Query: 127 EVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKP 186
           E+ P+DENGK L+   +LCATWEAME CKDAGL KS+GVSNFN R LE+ILNKPGLK+KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189

Query: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAK 246
           V NQVECHPYF Q KLL FC+  DIV+ AYS LG+ R   WV+ +SP LL+D +L +L K
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249

Query: 247 KHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYL 306
           ++ +T A I LR+ +QRGVVV+ KS+N +RI++N Q+F+F LT EEMK I+ LN+NVR++
Sbjct: 250 RYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFV 309

Query: 307 TLDIFAGPPNYPFSDEY 323
            L ++   P YPF DEY
Sbjct: 310 ELLMWRDHPEYPFHDEY 326


>gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]
          Length = 316

 Score =  320 bits (821), Expect = 8e-88
 Identities = 154/314 (49%), Positives = 214/314 (68%), Gaps = 4/314 (1%)

Query: 10  LNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKI 69
           LN+G  MP+LG GT+   + P  +  EAVK+AI+ G+ HID AHVY NE +VG+AI+ K+
Sbjct: 7   LNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63

Query: 70  ADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI 129
            +  VKRE++F  SKLW   H   LV+ A +++L +L+LDY+DLYLIH+P   KPG+E  
Sbjct: 64  REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123

Query: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCN 189
           P DE+G ++    ++  TW AME+  D GL K+IG+SNFNH  +EMILNKPGLKYKP  N
Sbjct: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183

Query: 190 QVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHK 249
           Q+ECHPY  Q KL+ +C+SK IV+ AYS LGS  + PW  P  P LLEDP + A+A KH 
Sbjct: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHN 242

Query: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD 309
           +T A + +R+ +QR +VV+ KS   +RI +N +VF+F+L+S++M  +   NRN R   L 
Sbjct: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302

Query: 310 IFAGPPNYPFSDEY 323
                 +YPF +E+
Sbjct: 303 SCTSHKDYPFHEEF 316


>gi|223468663 aldo-keto reductase family 1, member B10 [Homo
           sapiens]
          Length = 316

 Score =  307 bits (786), Expect = 9e-84
 Identities = 154/316 (48%), Positives = 209/316 (66%), Gaps = 4/316 (1%)

Query: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
           V+L+    MP++G GT+   + P  K  EAVK+AI+AG+ HID A+VY NE +VG AI+ 
Sbjct: 5   VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61

Query: 68  KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
           KI + +VKRED+F  SKLW       LVR A E++LK+L+L Y+D+YLIH+P   K G++
Sbjct: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121

Query: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
           + PKD+ G  +         WEAME+  D GL K++GVSNF+H  +E +LNKPGLKYKPV
Sbjct: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181

Query: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
            NQVECHPY  Q KL+ +C SK I + AYS LGS  + PW  P  P LLEDP +  +A K
Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLT 307
           HK+T A + +R+ +QR V+V+ KS    RI +N+QVF+F+L+ EEM  I   NRN R   
Sbjct: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300

Query: 308 LDIFAGPPNYPFSDEY 323
           +   +   +YPF+ EY
Sbjct: 301 VLQSSHLEDYPFNAEY 316


>gi|122937516 aldo-keto reductase family 1, member B10-like [Homo
           sapiens]
          Length = 316

 Score =  294 bits (752), Expect = 8e-80
 Identities = 148/316 (46%), Positives = 201/316 (63%), Gaps = 4/316 (1%)

Query: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67
           V+L+    MP++G GT+        K  EAVK+AI+A + HID A+ Y N+ +VG AI+ 
Sbjct: 5   VELSTKAKMPIVGLGTWRSL---LGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQE 61

Query: 68  KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
           KI + +V RED+F  SK+W       LVR A E++LK+L+L Y+D+YLIH+P   K G++
Sbjct: 62  KIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDD 121

Query: 128 VIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPV 187
             PKD+ G ++         WEAME+  D GL K++GVSNFNH  +E +LNKPGLKYKPV
Sbjct: 122 FFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPV 181

Query: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
            NQVECHPY  Q KL+ +C SK I + AYS LGS  + PW  P  P LLEDP +  +A K
Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLT 307
           HK+T A + +R+ +QR V V+ KS     I +N+QVF+F+L+ EEM  I   NRN R   
Sbjct: 241 HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD 300

Query: 308 LDIFAGPPNYPFSDEY 323
              F+   ++PF  EY
Sbjct: 301 FKEFSHLEDFPFDAEY 316


>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  270 bits (691), Expect = 1e-72
 Identities = 144/327 (44%), Positives = 214/327 (65%), Gaps = 16/327 (4%)

Query: 7   CVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIR 66
           CV L+ G  MP++G GT+  +E  + KA  AVK A+  G+ HID A +Y NE ++G A++
Sbjct: 5   CVLLHTGQKMPLIGLGTWK-SEPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61

Query: 67  SKIADG-SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
             +  G +V RE++F TSKLW+  H PE V PAL ++L +LQL+Y+DLYL+H+P + + G
Sbjct: 62  EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121

Query: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
           +   PK+ +G I +D+     TW+A+E     GL +++G+SNFN R ++ IL+   +  +
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179

Query: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALA 245
           P   QVECHPY  Q +L+  C+++ + + AYS LGS  +  W DP+ PVLLE+PV+ ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS-SDRAWRDPDEPVLLEEPVVLALA 238

Query: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRY 305
           +K+ R+PA I LR+Q+QR V+ + KS    RI QN++VF+F  + EEMK ++ LN+N RY
Sbjct: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298

Query: 306 ----LTLD-----IFAGPPNYPFSDEY 323
               LT+D       AG P YPF+D Y
Sbjct: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325


>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  270 bits (691), Expect = 1e-72
 Identities = 144/327 (44%), Positives = 214/327 (65%), Gaps = 16/327 (4%)

Query: 7   CVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIR 66
           CV L+ G  MP++G GT+  +E  + KA  AVK A+  G+ HID A +Y NE ++G A++
Sbjct: 5   CVLLHTGQKMPLIGLGTWK-SEPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61

Query: 67  SKIADG-SVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
             +  G +V RE++F TSKLW+  H PE V PAL ++L +LQL+Y+DLYL+H+P + + G
Sbjct: 62  EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121

Query: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
           +   PK+ +G I +D+     TW+A+E     GL +++G+SNFN R ++ IL+   +  +
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179

Query: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALA 245
           P   QVECHPY  Q +L+  C+++ + + AYS LGS  +  W DP+ PVLLE+PV+ ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS-SDRAWRDPDEPVLLEEPVVLALA 238

Query: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRY 305
           +K+ R+PA I LR+Q+QR V+ + KS    RI QN++VF+F  + EEMK ++ LN+N RY
Sbjct: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298

Query: 306 ----LTLD-----IFAGPPNYPFSDEY 323
               LT+D       AG P YPF+D Y
Sbjct: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325


>gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo
           sapiens]
          Length = 320

 Score =  270 bits (689), Expect = 2e-72
 Identities = 139/327 (42%), Positives = 199/327 (60%), Gaps = 29/327 (8%)

Query: 16  MPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVK 75
           +P +G  ++   +    K  EAVK AI+AG+ H D A+ Y+NE +VG  IR KI +G+V+
Sbjct: 4   IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60

Query: 76  REDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE--------- 126
           RED+F  +KLW   H+  LV  A  +SLK L+L+Y+DLYLIH+P+  KP           
Sbjct: 61  REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120

Query: 127 ----------EVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMI 176
                     + +P DE+  ++    D   TWEAME     GL K+IGVSNFNH  LE +
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180

Query: 177 LNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLL 236
           LNKPGL++KP+ NQ+ECHPY  Q+ L+ FC+S+D+ + AY  LG   E   VD     L+
Sbjct: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE--GVD-----LI 233

Query: 237 EDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAI 296
           ++PV+  +AK+H ++PA I +R+Q+QR V+V+  S     I++N+QVF+F+LT  +M  I
Sbjct: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293

Query: 297 DGLNRNVRYLTLDIFAGPPNYPFSDEY 323
             LNRN+R     I     +YPF  EY
Sbjct: 294 LSLNRNLRLAMFPITKNHKDYPFHIEY 320


>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
          Length = 139

 Score =  251 bits (640), Expect = 8e-67
 Identities = 123/123 (100%), Positives = 123/123 (100%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60
           MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SVK 123
           SVK
Sbjct: 121 SVK 123


>gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
           sapiens]
          Length = 249

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 48/146 (32%), Positives = 68/146 (46%), Gaps = 17/146 (11%)

Query: 28  EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A+   +  +E G   ID+A +Y++ +      GL +R   +D  VK   I   +
Sbjct: 24  DAPTSAAV--TRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78

Query: 84  KLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKIL 138
             W  NS +P+ VR  LE SLK LQ   VDL+ +H P    P EE +       + GK +
Sbjct: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138

Query: 139 FDTVDLCATWEAMEKCKDAGLAKSIG 164
              +   A WE  E C    L KS G
Sbjct: 139 ELGLSNYAAWEVAEICT---LCKSNG 161


>gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo
           sapiens]
          Length = 331

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 48/146 (32%), Positives = 68/146 (46%), Gaps = 17/146 (11%)

Query: 28  EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A+   +  +E G   ID+A +Y++ +      GL +R   +D  VK   I   +
Sbjct: 24  DAPTSAAV--TRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78

Query: 84  KLW-SNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKIL 138
             W  NS +P+ VR  LE SLK LQ   VDL+ +H P    P EE +       + GK +
Sbjct: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138

Query: 139 FDTVDLCATWEAMEKCKDAGLAKSIG 164
              +   A WE  E C    L KS G
Sbjct: 139 ELGLSNYAAWEVAEICT---LCKSNG 161


>gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]
          Length = 331

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 47/145 (32%), Positives = 67/145 (46%), Gaps = 15/145 (10%)

Query: 28  EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A+   +  +E G   ID+A VY+  +      GL +R   +D  VK +      
Sbjct: 24  DAPTSAAV--TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79

Query: 84  KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKILF 139
            L+ NS +P+ +R  LE SLK LQ   VDL+ +H P    P EE +       + GK + 
Sbjct: 80  PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139

Query: 140 DTVDLCATWEAMEKCKDAGLAKSIG 164
             +   A WE  E C    L KS G
Sbjct: 140 LGLSNYAAWEVAEICT---LCKSNG 161


>gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]
          Length = 359

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 47/146 (32%), Positives = 67/146 (45%), Gaps = 17/146 (11%)

Query: 28  EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A  AV+  +E G   +D+A +Y++ +      GL +     D  VK   I   +
Sbjct: 52  DAPASAA--AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKA 106

Query: 84  KLWSN-SHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPK----DENGKIL 138
             W   S +P+ VR  LE SLK LQ   VDL+ +H P    P EE +       + GK +
Sbjct: 107 NPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFV 166

Query: 139 FDTVDLCATWEAMEKCKDAGLAKSIG 164
              +   A+WE  E C    L KS G
Sbjct: 167 ELGLSNYASWEVAEICT---LCKSNG 189


>gi|27436964 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 3 [Homo sapiens]
          Length = 401

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%)

Query: 19  LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A   + +A E+G +  D+A VY     E  +G  I+ K     
Sbjct: 86  LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141

Query: 74  VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R  +  T+KL W      E       +   L+ SL+ LQL+YVD+   + P S  P E
Sbjct: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 201

Query: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
           E++       ++   + + T    + W AME  +   +A+   +                
Sbjct: 202 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 241

Query: 182 LKYKPVCNQVECHPYFNQR 200
               PVC Q E H +  ++
Sbjct: 242 --IPPVCEQAEYHLFQREK 258


>gi|27436962 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 2 [Homo sapiens]
          Length = 408

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%)

Query: 19  LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A   + +A E+G +  D+A VY     E  +G  I+ K     
Sbjct: 93  LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148

Query: 74  VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R  +  T+KL W      E       +   L+ SL+ LQL+YVD+   + P S  P E
Sbjct: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 208

Query: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
           E++       ++   + + T    + W AME  +   +A+   +                
Sbjct: 209 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 248

Query: 182 LKYKPVCNQVECHPYFNQR 200
               PVC Q E H +  ++
Sbjct: 249 --IPPVCEQAEYHLFQREK 265


>gi|27436966 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 1 [Homo sapiens]
          Length = 419

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%)

Query: 19  LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A   + +A E+G +  D+A VY     E  +G  I+ K     
Sbjct: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159

Query: 74  VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R  +  T+KL W      E       +   L+ SL+ LQL+YVD+   + P S  P E
Sbjct: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 219

Query: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
           E++       ++   + + T    + W AME  +   +A+   +                
Sbjct: 220 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 259

Query: 182 LKYKPVCNQVECHPYFNQR 200
               PVC Q E H +  ++
Sbjct: 260 --IPPVCEQAEYHLFQREK 276


>gi|4504825 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 1 [Homo sapiens]
          Length = 367

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 44/199 (22%), Positives = 80/199 (40%), Gaps = 43/199 (21%)

Query: 19  LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A + + LA + G +  D+A VY     E  +G  I+ K     
Sbjct: 52  LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----G 107

Query: 74  VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R  +  T+K+ W      E       +   L+ SL+ LQL+YVD+   + P    P E
Sbjct: 108 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPME 167

Query: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
           E +       ++   + + T    + W +ME  +   +A+   ++               
Sbjct: 168 ETVRAMTHVINQGMAMYWGT----SRWSSMEIMEAYSVARQFNLT--------------- 208

Query: 182 LKYKPVCNQVECHPYFNQR 200
               P+C Q E H +  ++
Sbjct: 209 ---PPICEQAEYHMFQREK 224


>gi|27436969 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 2 [Homo sapiens]
          Length = 353

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 44/199 (22%), Positives = 80/199 (40%), Gaps = 43/199 (21%)

Query: 19  LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A + + LA + G +  D+A VY     E  +G  I+ K     
Sbjct: 38  LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----G 93

Query: 74  VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R  +  T+K+ W      E       +   L+ SL+ LQL+YVD+   + P    P E
Sbjct: 94  WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPME 153

Query: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
           E +       ++   + + T    + W +ME  +   +A+   ++               
Sbjct: 154 ETVRAMTHVINQGMAMYWGT----SRWSSMEIMEAYSVARQFNLT--------------- 194

Query: 182 LKYKPVCNQVECHPYFNQR 200
               P+C Q E H +  ++
Sbjct: 195 ---PPICEQAEYHMFQREK 210


>gi|27436971 potassium voltage-gated channel, shaker-related
           subfamily, beta member 3 [Homo sapiens]
          Length = 404

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 16/123 (13%)

Query: 19  LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73
           LG GT+    +++    A + + +A E G +  D+A VY     E  +G  ++SK     
Sbjct: 93  LGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK----G 148

Query: 74  VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R     T+K+ W      E       +   L  SL+ LQL YVD+   +      P E
Sbjct: 149 WRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPME 208

Query: 127 EVI 129
           E++
Sbjct: 209 EIV 211


>gi|4503503 eukaryotic translation initiation factor 2B, subunit 1
           alpha, 26kDa [Homo sapiens]
          Length = 305

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 15/76 (19%)

Query: 176 ILNKPGLKYKPVCNQVECHPYF--------------NQRKLLDFCKSK-DIVLVAYSALG 220
           I+NK G     VC + +  P++              NQ+ + D  K K D + VA +   
Sbjct: 206 IINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQD 265

Query: 221 SHREEPWVDPNSPVLL 236
              E PWVD  +P L+
Sbjct: 266 LKEEHPWVDYTAPSLI 281


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)

Query: 66  RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
           R+ +   SV+ ED F+  +++S     EL+ P  E   +   +  +DL L+   +  KP 
Sbjct: 673 RTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLL-TRIPGKPY 731

Query: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAK 161
           +E  P     K + +     A  +A EK  + G  K
Sbjct: 732 KETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRK 767


>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSN 167
           P   N K LF  V+   T   +E CK+AG+ K I  S+
Sbjct: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145


>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSN 167
           P   N K LF  V+   T   +E CK+AG+ K I  S+
Sbjct: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,803,972
Number of Sequences: 37866
Number of extensions: 549022
Number of successful extensions: 1096
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1057
Number of HSP's gapped (non-prelim): 27
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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