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Search of human proteins with 4503101
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503101 cysteine and glycine-rich protein 2 [Homo sapiens]
(193 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503101 cysteine and glycine-rich protein 2 [Homo sapiens] 428 e-120
gi|4758086 cysteine and glycine-rich protein 1 isoform 1 [Homo s... 350 6e-97
gi|189083753 cysteine and glycine-rich protein 3 [Homo sapiens] 290 5e-79
gi|4502893 cysteine and glycine-rich protein 3 [Homo sapiens] 290 5e-79
gi|221316627 cysteine and glycine-rich protein 1 isoform 2 [Homo... 241 4e-64
gi|4503049 cysteine-rich protein 2 [Homo sapiens] 118 3e-27
gi|116517305 cysteine-rich protein 3 [Homo sapiens] 112 3e-25
gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens] 80 1e-15
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 69 2e-12
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 68 6e-12
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 68 6e-12
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 68 6e-12
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 68 6e-12
gi|194272207 actin binding LIM protein family, member 2 isoform ... 66 2e-11
gi|153792514 actin binding LIM protein family, member 2 isoform ... 66 2e-11
gi|194272204 actin binding LIM protein family, member 2 isoform ... 66 2e-11
gi|194272202 actin binding LIM protein family, member 2 isoform ... 66 2e-11
gi|194272200 actin binding LIM protein family, member 2 isoform ... 66 2e-11
gi|194272198 actin binding LIM protein family, member 2 isoform ... 66 2e-11
gi|194272196 actin binding LIM protein family, member 2 isoform ... 66 2e-11
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 65 3e-11
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 65 3e-11
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 65 3e-11
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 65 3e-11
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 65 3e-11
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 64 6e-11
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 63 1e-10
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 63 1e-10
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 63 1e-10
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 60 1e-09
>gi|4503101 cysteine and glycine-rich protein 2 [Homo sapiens]
Length = 193
Score = 428 bits (1100), Expect = e-120
Identities = 193/193 (100%), Positives = 193/193 (100%)
Query: 1 MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKS 60
MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKS
Sbjct: 1 MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKS 60
Query: 61 CYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCS 120
CYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCS
Sbjct: 61 CYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCS 120
Query: 121 RCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGF 180
RCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGF
Sbjct: 121 RCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGF 180
Query: 181 GYGQGAGALVHAQ 193
GYGQGAGALVHAQ
Sbjct: 181 GYGQGAGALVHAQ 193
>gi|4758086 cysteine and glycine-rich protein 1 isoform 1 [Homo
sapiens]
Length = 193
Score = 350 bits (897), Expect = 6e-97
Identities = 153/193 (79%), Positives = 169/193 (87%)
Query: 1 MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKS 60
MP WGGG KCG C +TVY AEEVQC+G SFH+ CFLCMVC+KNLDSTTVA+H EEIYCKS
Sbjct: 1 MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKS 60
Query: 61 CYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCS 120
CYGKKYGPKGYGYGQGAGTL+ D+GE LGIK E HRPTTNPN SKFAQK GG+E+C
Sbjct: 61 CYGKKYGPKGYGYGQGAGTLSTDKGESLGIKHEEAPGHRPTTNPNASKFAQKIGGSERCP 120
Query: 121 RCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGF 180
RC +VYAAEK+IGAGK WHK CFRCAKCGK LESTTL +K+GEIYCKGCYAKNFGPKGF
Sbjct: 121 RCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLADKDGEIYCKGCYAKNFGPKGF 180
Query: 181 GYGQGAGALVHAQ 193
G+GQGAGALVH++
Sbjct: 181 GFGQGAGALVHSE 193
>gi|189083753 cysteine and glycine-rich protein 3 [Homo sapiens]
Length = 194
Score = 290 bits (742), Expect = 5e-79
Identities = 127/184 (69%), Positives = 148/184 (80%), Gaps = 1/184 (0%)
Query: 1 MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKS 60
MP WGGG KCGAC +TVYHAEE+QC+GRSFH+ CF CM CRK LDSTTVA H+ EIYCK
Sbjct: 1 MPNWGGGAKCGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYCKV 60
Query: 61 CYGKKYGPKGYGYGQGAGTLNMDRGERLGIK-PESVQPHRPTTNPNTSKFAQKYGGAEKC 119
CYG++YGPKG GYGQGAG L+ D GE LG++ +S +P R T N SKF K+G +EKC
Sbjct: 61 CYGRRYGPKGIGYGQGAGCLSTDTGEHLGLQFQQSPKPARSVTTSNPSKFTAKFGESEKC 120
Query: 120 SRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKG 179
RCG SVYAAEK++G GKPWHK CFRCA CGKSLEST +T+K+GE+YCK CYAKNFGP G
Sbjct: 121 PRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAKNFGPTG 180
Query: 180 FGYG 183
G+G
Sbjct: 181 IGFG 184
Score = 98.6 bits (244), Expect = 3e-21
Identities = 42/77 (54%), Positives = 52/77 (67%)
Query: 113 YGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYA 172
+GG KC C +VY AE+I G+ +HK CF C C K+L+STT+ E EIYCK CY
Sbjct: 4 WGGGAKCGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYCKVCYG 63
Query: 173 KNFGPKGFGYGQGAGAL 189
+ +GPKG GYGQGAG L
Sbjct: 64 RRYGPKGIGYGQGAGCL 80
>gi|4502893 cysteine and glycine-rich protein 3 [Homo sapiens]
Length = 194
Score = 290 bits (742), Expect = 5e-79
Identities = 127/184 (69%), Positives = 148/184 (80%), Gaps = 1/184 (0%)
Query: 1 MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKS 60
MP WGGG KCGAC +TVYHAEE+QC+GRSFH+ CF CM CRK LDSTTVA H+ EIYCK
Sbjct: 1 MPNWGGGAKCGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYCKV 60
Query: 61 CYGKKYGPKGYGYGQGAGTLNMDRGERLGIK-PESVQPHRPTTNPNTSKFAQKYGGAEKC 119
CYG++YGPKG GYGQGAG L+ D GE LG++ +S +P R T N SKF K+G +EKC
Sbjct: 61 CYGRRYGPKGIGYGQGAGCLSTDTGEHLGLQFQQSPKPARSVTTSNPSKFTAKFGESEKC 120
Query: 120 SRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKG 179
RCG SVYAAEK++G GKPWHK CFRCA CGKSLEST +T+K+GE+YCK CYAKNFGP G
Sbjct: 121 PRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAKNFGPTG 180
Query: 180 FGYG 183
G+G
Sbjct: 181 IGFG 184
Score = 98.6 bits (244), Expect = 3e-21
Identities = 42/77 (54%), Positives = 52/77 (67%)
Query: 113 YGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYA 172
+GG KC C +VY AE+I G+ +HK CF C C K+L+STT+ E EIYCK CY
Sbjct: 4 WGGGAKCGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYCKVCYG 63
Query: 173 KNFGPKGFGYGQGAGAL 189
+ +GPKG GYGQGAG L
Sbjct: 64 RRYGPKGIGYGQGAGCL 80
>gi|221316627 cysteine and glycine-rich protein 1 isoform 2 [Homo
sapiens]
Length = 140
Score = 241 bits (614), Expect = 4e-64
Identities = 106/137 (77%), Positives = 117/137 (85%)
Query: 1 MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKS 60
MP WGGG KCG C +TVY AEEVQC+G SFH+ CFLCMVC+KNLDSTTVA+H EEIYCKS
Sbjct: 1 MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKS 60
Query: 61 CYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCS 120
CYGKKYGPKGYGYGQGAGTL+ D+GE LGIK E HRPTTNPN SKFAQK GG+E+C
Sbjct: 61 CYGKKYGPKGYGYGQGAGTLSTDKGESLGIKHEEAPGHRPTTNPNASKFAQKIGGSERCP 120
Query: 121 RCGDSVYAAEKIIGAGK 137
RC +VYAAEK+IGAGK
Sbjct: 121 RCSQAVYAAEKVIGAGK 137
Score = 96.7 bits (239), Expect = 1e-20
Identities = 41/77 (53%), Positives = 53/77 (68%)
Query: 113 YGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYA 172
+GG +KC C +VY AE++ G +HK+CF C C K+L+STT+ EIYCK CY
Sbjct: 4 WGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKSCYG 63
Query: 173 KNFGPKGFGYGQGAGAL 189
K +GPKG+GYGQGAG L
Sbjct: 64 KKYGPKGYGYGQGAGTL 80
>gi|4503049 cysteine-rich protein 2 [Homo sapiens]
Length = 208
Score = 118 bits (296), Expect = 3e-27
Identities = 68/190 (35%), Positives = 91/190 (47%), Gaps = 15/190 (7%)
Query: 8 NKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYC-KSCYGKKY 66
+KC C +TVY AE+V G+ +H+ C C C K L A HD + +C K CY +
Sbjct: 3 SKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYATLF 62
Query: 67 GPKGYGYGQGAGTLNMDRGERLG-----------IKPESVQPHRPTTNPNTSKFAQKYGG 115
GPKG G GAG+ ++ G + E + P P+ + + G
Sbjct: 63 GPKGVNIG-GAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTG 121
Query: 116 AEK-CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYC-KGCYAK 173
C RC VY AEK+ GK WH+ C RC +CGK+L E +G+ YC K CY
Sbjct: 122 EPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYGI 181
Query: 174 NFGPKGFGYG 183
FGPKG G
Sbjct: 182 LFGPKGVNTG 191
Score = 75.5 bits (184), Expect = 3e-14
Identities = 35/77 (45%), Positives = 47/77 (61%), Gaps = 2/77 (2%)
Query: 116 AEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYC-KGCYAKN 174
A KC +C +VY AEK+ GK WHK C +C +C K+L E +G+ +C K CYA
Sbjct: 2 ASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYATL 61
Query: 175 FGPKGFGYGQGAGALVH 191
FGPKG G GAG+ ++
Sbjct: 62 FGPKGVNIG-GAGSYIY 77
Score = 62.0 bits (149), Expect = 3e-10
Identities = 35/89 (39%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 5 GGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYC-KSCYG 63
G N C C + VY AE+V G+ +HR C C C K L A HD + YC K CYG
Sbjct: 121 GEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYG 180
Query: 64 KKYGPKGYGYGQGAGTLNMDRGERLGIKP 92
+GPKG G G+ DR ++P
Sbjct: 181 ILFGPKGVNTG-AVGSYIYDRDPEGKVQP 208
>gi|116517305 cysteine-rich protein 3 [Homo sapiens]
Length = 204
Score = 112 bits (279), Expect = 3e-25
Identities = 65/186 (34%), Positives = 88/186 (47%), Gaps = 13/186 (6%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYC-KSCYGKKYGP 68
C C + V+ AE+V G+++HR C C C L A H+ YC K CYG +GP
Sbjct: 5 CPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGP 64
Query: 69 KGYGYGQGAGTL-----NMDRGERLGIKPESVQPHRPTTNPNTSKFAQKY-----GGAEK 118
+G G G G+ G + P S P RP T K + + G
Sbjct: 65 RGVNIG-GVGSYLYNPPTPSPGCTTPLSPSSFSPPRPRTGLPQGKKSPPHMKTFTGETSL 123
Query: 119 CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK-GCYAKNFGP 177
C CG+ VY AEK++ G+ WH+ C RC +C K+L + + E +G YC CY FGP
Sbjct: 124 CPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCHVPCYGYLFGP 183
Query: 178 KGFGYG 183
KG G
Sbjct: 184 KGVNIG 189
Score = 62.4 bits (150), Expect = 2e-10
Identities = 31/71 (43%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Query: 5 GGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCK-SCYG 63
G + C CG VY AE+V GR++HR C C C K L + + A HD YC CYG
Sbjct: 119 GETSLCPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCHVPCYG 178
Query: 64 KKYGPKGYGYG 74
+GPKG G
Sbjct: 179 YLFGPKGVNIG 189
>gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens]
Length = 77
Score = 80.1 bits (196), Expect = 1e-15
Identities = 35/67 (52%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Query: 118 KCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK-GCYAKNFG 176
KC +C VY AE++ GK WH+ C +C KCGK+L S E EG+ YC CYA FG
Sbjct: 3 KCPKCNKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCNHPCYAAMFG 62
Query: 177 PKGFGYG 183
PKGFG G
Sbjct: 63 PKGFGRG 69
Score = 60.5 bits (145), Expect = 9e-10
Identities = 29/67 (43%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 9 KCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCK-SCYGKKYG 67
KC C + VY AE V G+ +HR C C C K L S A H+ + YC CY +G
Sbjct: 3 KCPKCNKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCNHPCYAAMFG 62
Query: 68 PKGYGYG 74
PKG+G G
Sbjct: 63 PKGFGRG 69
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 69.3 bits (168), Expect = 2e-12
Identities = 40/173 (23%), Positives = 64/173 (36%), Gaps = 51/173 (29%)
Query: 8 NKCGACGRTVYH-AEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C C + + H + E+ + R FH CF C C+++L D E+ C CY +
Sbjct: 38 NTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAF 97
Query: 67 GPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSV 126
+ +CS CG++V
Sbjct: 98 -------------------------------------------------SSQCSACGETV 108
Query: 127 Y-AAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
+ K+ G+ WH++CF C+ C + L S + +G YC CY F P+
Sbjct: 109 MPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPR 161
Score = 67.4 bits (163), Expect = 7e-12
Identities = 48/185 (25%), Positives = 77/185 (41%), Gaps = 30/185 (16%)
Query: 8 NKCGACGRTVYH-AEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
++C ACG TV + +++ G+++H CFLC C + L S + YC CY K+
Sbjct: 99 SQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKF 158
Query: 67 GPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRP---TTNPNTSKFAQKYGGAEK---CS 120
P+ + + TL G+ HR T T Q++ ++ C
Sbjct: 159 APR---CARCSKTLTQG-----GVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCV 210
Query: 121 RCGDSVYAAE------KIIGAG---------KPWHKNCFRCAKCGKSLESTTLTEKEGEI 165
C ++A + I+G G + WH NCF CA+C SL ++
Sbjct: 211 ACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQV 270
Query: 166 YCKGC 170
C+GC
Sbjct: 271 LCQGC 275
Score = 43.9 bits (102), Expect = 9e-05
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 116 AEKCSRCGDSV-YAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174
A C+ C + + + ++ + +H+ CFRC +C +SL T ++ E+ C CY
Sbjct: 37 ANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSA 96
Query: 175 FGPKGFGYGQ 184
F + G+
Sbjct: 97 FSSQCSACGE 106
Score = 29.3 bits (64), Expect = 2.2
Identities = 12/32 (37%), Positives = 15/32 (46%)
Query: 144 FRCAKCGKSLESTTLTEKEGEIYCKGCYAKNF 175
F CAKC +SL + + YC CY F
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTF 36
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 67.8 bits (164), Expect = 6e-12
Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 14/187 (7%)
Query: 8 NKCGACGRTV-YHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C CG+ + +++ R +H CF C CR +L A ++++ C CY +Y
Sbjct: 38 NTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEY 97
Query: 67 GPKGYGYGQG--AGTLNMD-RG----ERLGI-----KPESVQPHRPTTNPNTSKFAQKYG 114
K + GT M+ +G E I +P + P N N +
Sbjct: 98 SSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQ 157
Query: 115 GAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174
A +C +C + + +PWHK CF C C K L T ++ YC C+
Sbjct: 158 HAMQCVQCKKPI-TTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDL 216
Query: 175 FGPKGFG 181
+ K G
Sbjct: 217 YAKKCAG 223
Score = 50.4 bits (119), Expect = 9e-07
Identities = 39/174 (22%), Positives = 54/174 (31%), Gaps = 57/174 (32%)
Query: 8 NKCGACGRTVYHAEEVQCDG-----------RSFHRCCFLCMVCRKNLDSTTVAIHDEEI 56
N C C + + VQC + +H+ CF+C CRK L D+
Sbjct: 148 NFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFA 207
Query: 57 YCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGA 116
YC +C+ Y K G TNP + KY
Sbjct: 208 YCLNCFCDLYAKKCAG----------------------------CTNPISGLGGTKYISF 239
Query: 117 EKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGC 170
E+ + WH +CF C KC SL + +I C C
Sbjct: 240 EE------------------RQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 45.4 bits (106), Expect = 3e-05
Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 116 AEKCSRCGDSVYAAEKIIG-AGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174
A C CG + K + + WH+ CF C++C SL KE ++ C CY+
Sbjct: 37 ANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNE 96
Query: 175 FGPK 178
+ K
Sbjct: 97 YSSK 100
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 67.8 bits (164), Expect = 6e-12
Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 14/187 (7%)
Query: 8 NKCGACGRTV-YHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C CG+ + +++ R +H CF C CR +L A ++++ C CY +Y
Sbjct: 38 NTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEY 97
Query: 67 GPKGYGYGQG--AGTLNMD-RG----ERLGI-----KPESVQPHRPTTNPNTSKFAQKYG 114
K + GT M+ +G E I +P + P N N +
Sbjct: 98 SSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQ 157
Query: 115 GAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174
A +C +C + + +PWHK CF C C K L T ++ YC C+
Sbjct: 158 HAMQCVQCKKPI-TTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDL 216
Query: 175 FGPKGFG 181
+ K G
Sbjct: 217 YAKKCAG 223
Score = 50.4 bits (119), Expect = 9e-07
Identities = 39/174 (22%), Positives = 54/174 (31%), Gaps = 57/174 (32%)
Query: 8 NKCGACGRTVYHAEEVQCDG-----------RSFHRCCFLCMVCRKNLDSTTVAIHDEEI 56
N C C + + VQC + +H+ CF+C CRK L D+
Sbjct: 148 NFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFA 207
Query: 57 YCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGA 116
YC +C+ Y K G TNP + KY
Sbjct: 208 YCLNCFCDLYAKKCAG----------------------------CTNPISGLGGTKYISF 239
Query: 117 EKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGC 170
E+ + WH +CF C KC SL + +I C C
Sbjct: 240 EE------------------RQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 45.4 bits (106), Expect = 3e-05
Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 116 AEKCSRCGDSVYAAEKIIG-AGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174
A C CG + K + + WH+ CF C++C SL KE ++ C CY+
Sbjct: 37 ANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNE 96
Query: 175 FGPK 178
+ K
Sbjct: 97 YSSK 100
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 67.8 bits (164), Expect = 6e-12
Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 14/187 (7%)
Query: 8 NKCGACGRTV-YHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C CG+ + +++ R +H CF C CR +L A ++++ C CY +Y
Sbjct: 38 NTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEY 97
Query: 67 GPKGYGYGQG--AGTLNMD-RG----ERLGI-----KPESVQPHRPTTNPNTSKFAQKYG 114
K + GT M+ +G E I +P + P N N +
Sbjct: 98 SSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQ 157
Query: 115 GAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174
A +C +C + + +PWHK CF C C K L T ++ YC C+
Sbjct: 158 HAMQCVQCKKPI-TTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDL 216
Query: 175 FGPKGFG 181
+ K G
Sbjct: 217 YAKKCAG 223
Score = 50.4 bits (119), Expect = 9e-07
Identities = 39/174 (22%), Positives = 54/174 (31%), Gaps = 57/174 (32%)
Query: 8 NKCGACGRTVYHAEEVQCDG-----------RSFHRCCFLCMVCRKNLDSTTVAIHDEEI 56
N C C + + VQC + +H+ CF+C CRK L D+
Sbjct: 148 NFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFA 207
Query: 57 YCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGA 116
YC +C+ Y K G TNP + KY
Sbjct: 208 YCLNCFCDLYAKKCAG----------------------------CTNPISGLGGTKYISF 239
Query: 117 EKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGC 170
E+ + WH +CF C KC SL + +I C C
Sbjct: 240 EE------------------RQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 45.4 bits (106), Expect = 3e-05
Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 116 AEKCSRCGDSVYAAEKIIG-AGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174
A C CG + K + + WH+ CF C++C SL KE ++ C CY+
Sbjct: 37 ANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNE 96
Query: 175 FGPK 178
+ K
Sbjct: 97 YSSK 100
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 67.8 bits (164), Expect = 6e-12
Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 14/187 (7%)
Query: 8 NKCGACGRTV-YHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C CG+ + +++ R +H CF C CR +L A ++++ C CY +Y
Sbjct: 38 NTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEY 97
Query: 67 GPKGYGYGQG--AGTLNMD-RG----ERLGI-----KPESVQPHRPTTNPNTSKFAQKYG 114
K + GT M+ +G E I +P + P N N +
Sbjct: 98 SSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQ 157
Query: 115 GAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174
A +C +C + + +PWHK CF C C K L T ++ YC C+
Sbjct: 158 HAMQCVQCKKPI-TTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDL 216
Query: 175 FGPKGFG 181
+ K G
Sbjct: 217 YAKKCAG 223
Score = 50.4 bits (119), Expect = 9e-07
Identities = 39/174 (22%), Positives = 54/174 (31%), Gaps = 57/174 (32%)
Query: 8 NKCGACGRTVYHAEEVQCDG-----------RSFHRCCFLCMVCRKNLDSTTVAIHDEEI 56
N C C + + VQC + +H+ CF+C CRK L D+
Sbjct: 148 NFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFA 207
Query: 57 YCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGA 116
YC +C+ Y K G TNP + KY
Sbjct: 208 YCLNCFCDLYAKKCAG----------------------------CTNPISGLGGTKYISF 239
Query: 117 EKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGC 170
E+ + WH +CF C KC SL + +I C C
Sbjct: 240 EE------------------RQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 45.4 bits (106), Expect = 3e-05
Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 116 AEKCSRCGDSVYAAEKIIG-AGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174
A C CG + K + + WH+ CF C++C SL KE ++ C CY+
Sbjct: 37 ANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNE 96
Query: 175 FGPK 178
+ K
Sbjct: 97 YSSK 100
>gi|194272207 actin binding LIM protein family, member 2 isoform 7
[Homo sapiens]
Length = 470
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/188 (22%), Positives = 68/188 (36%), Gaps = 23/188 (12%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPK 69
C CG V E ++ + FH CF+C C +L + E C Y + YG +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 70 GYGYGQ---------------------GAGTLNMDRGERLGIKPESVQPHRPTTNPNTSK 108
+ Q L G+R+ + + + +
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 109 FAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
A G C CG + + ++ K WH CF+C CGK L + ++ K+G YC+
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCE 201
Query: 169 GCYAKNFG 176
Y FG
Sbjct: 202 ADYHAKFG 209
Score = 37.4 bits (85), Expect = 0.008
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 6 GGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKK 65
G CG CG + + + + + +H CF C C K L++ ++ D YC++ Y K
Sbjct: 149 GLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCEADYHAK 207
Query: 66 YG 67
+G
Sbjct: 208 FG 209
Score = 35.0 bits (79), Expect = 0.040
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 119 CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
C+ CG+ V E + K +H CF C CG L ++GE C Y + +G +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 179 GFGYGQ 184
F Q
Sbjct: 83 CFSCDQ 88
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/188 (22%), Positives = 68/188 (36%), Gaps = 23/188 (12%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPK 69
C CG V E ++ + FH CF+C C +L + E C Y + YG +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 70 GYGYGQ---------------------GAGTLNMDRGERLGIKPESVQPHRPTTNPNTSK 108
+ Q L G+R+ + + + +
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 109 FAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
A G C CG + + ++ K WH CF+C CGK L + ++ K+G YC+
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCE 201
Query: 169 GCYAKNFG 176
Y FG
Sbjct: 202 ADYHAKFG 209
Score = 37.4 bits (85), Expect = 0.008
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 6 GGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKK 65
G CG CG + + + + + +H CF C C K L++ ++ D YC++ Y K
Sbjct: 149 GLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCEADYHAK 207
Query: 66 YG 67
+G
Sbjct: 208 FG 209
Score = 35.0 bits (79), Expect = 0.040
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 119 CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
C+ CG+ V E + K +H CF C CG L ++GE C Y + +G +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 179 GFGYGQ 184
F Q
Sbjct: 83 CFSCDQ 88
>gi|194272204 actin binding LIM protein family, member 2 isoform 5
[Homo sapiens]
Length = 531
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/188 (22%), Positives = 68/188 (36%), Gaps = 23/188 (12%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPK 69
C CG V E ++ + FH CF+C C +L + E C Y + YG +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 70 GYGYGQ---------------------GAGTLNMDRGERLGIKPESVQPHRPTTNPNTSK 108
+ Q L G+R+ + + + +
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 109 FAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
A G C CG + + ++ K WH CF+C CGK L + ++ K+G YC+
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCE 201
Query: 169 GCYAKNFG 176
Y FG
Sbjct: 202 ADYHAKFG 209
Score = 37.4 bits (85), Expect = 0.008
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 6 GGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKK 65
G CG CG + + + + + +H CF C C K L++ ++ D YC++ Y K
Sbjct: 149 GLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCEADYHAK 207
Query: 66 YG 67
+G
Sbjct: 208 FG 209
Score = 35.0 bits (79), Expect = 0.040
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 119 CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
C+ CG+ V E + K +H CF C CG L ++GE C Y + +G +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 179 GFGYGQ 184
F Q
Sbjct: 83 CFSCDQ 88
>gi|194272202 actin binding LIM protein family, member 2 isoform 4
[Homo sapiens]
Length = 559
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/188 (22%), Positives = 68/188 (36%), Gaps = 23/188 (12%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPK 69
C CG V E ++ + FH CF+C C +L + E C Y + YG +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 70 GYGYGQ---------------------GAGTLNMDRGERLGIKPESVQPHRPTTNPNTSK 108
+ Q L G+R+ + + + +
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 109 FAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
A G C CG + + ++ K WH CF+C CGK L + ++ K+G YC+
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCE 201
Query: 169 GCYAKNFG 176
Y FG
Sbjct: 202 ADYHAKFG 209
Score = 37.4 bits (85), Expect = 0.008
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 6 GGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKK 65
G CG CG + + + + + +H CF C C K L++ ++ D YC++ Y K
Sbjct: 149 GLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCEADYHAK 207
Query: 66 YG 67
+G
Sbjct: 208 FG 209
Score = 35.0 bits (79), Expect = 0.040
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 119 CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
C+ CG+ V E + K +H CF C CG L ++GE C Y + +G +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 179 GFGYGQ 184
F Q
Sbjct: 83 CFSCDQ 88
>gi|194272200 actin binding LIM protein family, member 2 isoform 3
[Homo sapiens]
Length = 572
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/188 (22%), Positives = 68/188 (36%), Gaps = 23/188 (12%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPK 69
C CG V E ++ + FH CF+C C +L + E C Y + YG +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 70 GYGYGQ---------------------GAGTLNMDRGERLGIKPESVQPHRPTTNPNTSK 108
+ Q L G+R+ + + + +
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 109 FAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
A G C CG + + ++ K WH CF+C CGK L + ++ K+G YC+
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCE 201
Query: 169 GCYAKNFG 176
Y FG
Sbjct: 202 ADYHAKFG 209
Score = 37.4 bits (85), Expect = 0.008
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 6 GGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKK 65
G CG CG + + + + + +H CF C C K L++ ++ D YC++ Y K
Sbjct: 149 GLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCEADYHAK 207
Query: 66 YG 67
+G
Sbjct: 208 FG 209
Score = 35.0 bits (79), Expect = 0.040
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 119 CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
C+ CG+ V E + K +H CF C CG L ++GE C Y + +G +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 179 GFGYGQ 184
F Q
Sbjct: 83 CFSCDQ 88
>gi|194272198 actin binding LIM protein family, member 2 isoform 2
[Homo sapiens]
Length = 611
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/188 (22%), Positives = 68/188 (36%), Gaps = 23/188 (12%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPK 69
C CG V E ++ + FH CF+C C +L + E C Y + YG +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 70 GYGYGQ---------------------GAGTLNMDRGERLGIKPESVQPHRPTTNPNTSK 108
+ Q L G+R+ + + + +
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 109 FAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
A G C CG + + ++ K WH CF+C CGK L + ++ K+G YC+
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCE 201
Query: 169 GCYAKNFG 176
Y FG
Sbjct: 202 ADYHAKFG 209
Score = 37.4 bits (85), Expect = 0.008
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 6 GGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKK 65
G CG CG + + + + + +H CF C C K L++ ++ D YC++ Y K
Sbjct: 149 GLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCEADYHAK 207
Query: 66 YG 67
+G
Sbjct: 208 FG 209
Score = 35.0 bits (79), Expect = 0.040
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 119 CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
C+ CG+ V E + K +H CF C CG L ++GE C Y + +G +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 179 GFGYGQ 184
F Q
Sbjct: 83 CFSCDQ 88
>gi|194272196 actin binding LIM protein family, member 2 isoform 1
[Homo sapiens]
Length = 645
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/188 (22%), Positives = 68/188 (36%), Gaps = 23/188 (12%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPK 69
C CG V E ++ + FH CF+C C +L + E C Y + YG +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 70 GYGYGQ---------------------GAGTLNMDRGERLGIKPESVQPHRPTTNPNTSK 108
+ Q L G+R+ + + + +
Sbjct: 83 CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
Query: 109 FAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
A G C CG + + ++ K WH CF+C CGK L + ++ K+G YC+
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCE 201
Query: 169 GCYAKNFG 176
Y FG
Sbjct: 202 ADYHAKFG 209
Score = 37.4 bits (85), Expect = 0.008
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 6 GGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKK 65
G CG CG + + + + + +H CF C C K L++ ++ D YC++ Y K
Sbjct: 149 GLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYIS-KDGLPYCEADYHAK 207
Query: 66 YG 67
+G
Sbjct: 208 FG 209
Score = 35.0 bits (79), Expect = 0.040
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 119 CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
C+ CG+ V E + K +H CF C CG L ++GE C Y + +G +
Sbjct: 24 CNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
Query: 179 GFGYGQ 184
F Q
Sbjct: 83 CFSCDQ 88
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 65.5 bits (158), Expect = 3e-11
Identities = 56/206 (27%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 8 NKCGACGRTV-YHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C C + + ++EV R +H CF C C L + T D +I C C ++
Sbjct: 38 NTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTRED 97
Query: 67 GPKGYGYGQG--AGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGD 124
PK G + AG N++ + K + T F K G C C +
Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHK-DCFTCSNCKQVIGTGSFFPK-GEDFYCVTCHE 155
Query: 125 SVYA-----AEKIIGAG------KPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAK 173
+ +A K I +G +PWH +CF C C K L T E + YC CY K
Sbjct: 156 TKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY-K 214
Query: 174 NFGPKG--------FGYGQGAGALVH 191
NF K G+G+G+ + +
Sbjct: 215 NFVAKKCAGCKNPITGFGKGSSVVAY 240
Score = 53.1 bits (126), Expect = 1e-07
Identities = 42/185 (22%), Positives = 70/185 (37%), Gaps = 25/185 (13%)
Query: 9 KCGACGRTVYHAEE-VQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYG 67
KC C + + ++ V+ G +H+ CF C C++ + + + E+ YC +C+ K+
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
Query: 68 PKGYGYGQG---AGTLNMDRGERLGI-------KPESVQPHRPTTNPNTSKFAQKYGGAE 117
+ G D+ K + Q + K A+
Sbjct: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
Query: 118 KCSRC---------GDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
KC+ C G SV A E G+ WH CF C KC +L + + ++YC
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYE-----GQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCP 274
Query: 169 GCYAK 173
C K
Sbjct: 275 DCAKK 279
Score = 46.6 bits (109), Expect = 1e-05
Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 14/84 (16%)
Query: 108 KFAQKYGGAEKCSRCGDSVYA-----AEKIIGAGKP--------WHKNCFRCAKCGKSLE 154
K+ QK G C +C D A K IGA WH CFRCAKC L
Sbjct: 18 KYVQK-DGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLA 76
Query: 155 STTLTEKEGEIYCKGCYAKNFGPK 178
+ T K+ +I C C + PK
Sbjct: 77 NETFVAKDNKILCNKCTTREDSPK 100
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 65.5 bits (158), Expect = 3e-11
Identities = 56/206 (27%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 8 NKCGACGRTV-YHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C C + + ++EV R +H CF C C L + T D +I C C ++
Sbjct: 38 NTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTRED 97
Query: 67 GPKGYGYGQG--AGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGD 124
PK G + AG N++ + K + T F K G C C +
Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHK-DCFTCSNCKQVIGTGSFFPK-GEDFYCVTCHE 155
Query: 125 SVYA-----AEKIIGAG------KPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAK 173
+ +A K I +G +PWH +CF C C K L T E + YC CY K
Sbjct: 156 TKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY-K 214
Query: 174 NFGPKG--------FGYGQGAGALVH 191
NF K G+G+G+ + +
Sbjct: 215 NFVAKKCAGCKNPITGFGKGSSVVAY 240
Score = 53.1 bits (126), Expect = 1e-07
Identities = 42/185 (22%), Positives = 70/185 (37%), Gaps = 25/185 (13%)
Query: 9 KCGACGRTVYHAEE-VQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYG 67
KC C + + ++ V+ G +H+ CF C C++ + + + E+ YC +C+ K+
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
Query: 68 PKGYGYGQG---AGTLNMDRGERLGI-------KPESVQPHRPTTNPNTSKFAQKYGGAE 117
+ G D+ K + Q + K A+
Sbjct: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
Query: 118 KCSRC---------GDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
KC+ C G SV A E G+ WH CF C KC +L + + ++YC
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYE-----GQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCP 274
Query: 169 GCYAK 173
C K
Sbjct: 275 DCAKK 279
Score = 46.6 bits (109), Expect = 1e-05
Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 14/84 (16%)
Query: 108 KFAQKYGGAEKCSRCGDSVYA-----AEKIIGAGKP--------WHKNCFRCAKCGKSLE 154
K+ QK G C +C D A K IGA WH CFRCAKC L
Sbjct: 18 KYVQK-DGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLA 76
Query: 155 STTLTEKEGEIYCKGCYAKNFGPK 178
+ T K+ +I C C + PK
Sbjct: 77 NETFVAKDNKILCNKCTTREDSPK 100
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 65.5 bits (158), Expect = 3e-11
Identities = 56/206 (27%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 8 NKCGACGRTV-YHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C C + + ++EV R +H CF C C L + T D +I C C ++
Sbjct: 67 NTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTRED 126
Query: 67 GPKGYGYGQG--AGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGD 124
PK G + AG N++ + K + T F K G C C +
Sbjct: 127 SPKCKGCFKAIVAGDQNVEYKGTVWHK-DCFTCSNCKQVIGTGSFFPK-GEDFYCVTCHE 184
Query: 125 SVYA-----AEKIIGAG------KPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAK 173
+ +A K I +G +PWH +CF C C K L T E + YC CY K
Sbjct: 185 TKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY-K 243
Query: 174 NFGPKG--------FGYGQGAGALVH 191
NF K G+G+G+ + +
Sbjct: 244 NFVAKKCAGCKNPITGFGKGSSVVAY 269
Score = 53.1 bits (126), Expect = 1e-07
Identities = 42/185 (22%), Positives = 70/185 (37%), Gaps = 25/185 (13%)
Query: 9 KCGACGRTVYHAEE-VQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYG 67
KC C + + ++ V+ G +H+ CF C C++ + + + E+ YC +C+ K+
Sbjct: 129 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 188
Query: 68 PKGYGYGQG---AGTLNMDRGERLGI-------KPESVQPHRPTTNPNTSKFAQKYGGAE 117
+ G D+ K + Q + K A+
Sbjct: 189 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 248
Query: 118 KCSRC---------GDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
KC+ C G SV A E G+ WH CF C KC +L + + ++YC
Sbjct: 249 KCAGCKNPITGFGKGSSVVAYE-----GQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCP 303
Query: 169 GCYAK 173
C K
Sbjct: 304 DCAKK 308
Score = 47.0 bits (110), Expect = 1e-05
Identities = 32/105 (30%), Positives = 40/105 (38%), Gaps = 14/105 (13%)
Query: 87 RLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYA-----AEKIIGAGKP--- 138
++G E H K+ QK G C +C D A K IGA
Sbjct: 26 KVGTMAEKFDCHYCRDPLQGKKYVQK-DGHHCCLKCFDKFCANTCVECRKPIGADSKEVH 84
Query: 139 -----WHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
WH CFRCAKC L + T K+ +I C C + PK
Sbjct: 85 YKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPK 129
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 65.5 bits (158), Expect = 3e-11
Identities = 56/206 (27%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 8 NKCGACGRTV-YHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C C + + ++EV R +H CF C C L + T D +I C C ++
Sbjct: 54 NTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTRED 113
Query: 67 GPKGYGYGQG--AGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGD 124
PK G + AG N++ + K + T F K G C C +
Sbjct: 114 SPKCKGCFKAIVAGDQNVEYKGTVWHK-DCFTCSNCKQVIGTGSFFPK-GEDFYCVTCHE 171
Query: 125 SVYA-----AEKIIGAG------KPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAK 173
+ +A K I +G +PWH +CF C C K L T E + YC CY K
Sbjct: 172 TKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY-K 230
Query: 174 NFGPKG--------FGYGQGAGALVH 191
NF K G+G+G+ + +
Sbjct: 231 NFVAKKCAGCKNPITGFGKGSSVVAY 256
Score = 53.1 bits (126), Expect = 1e-07
Identities = 42/185 (22%), Positives = 70/185 (37%), Gaps = 25/185 (13%)
Query: 9 KCGACGRTVYHAEE-VQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYG 67
KC C + + ++ V+ G +H+ CF C C++ + + + E+ YC +C+ K+
Sbjct: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175
Query: 68 PKGYGYGQG---AGTLNMDRGERLGI-------KPESVQPHRPTTNPNTSKFAQKYGGAE 117
+ G D+ K + Q + K A+
Sbjct: 176 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235
Query: 118 KCSRC---------GDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
KC+ C G SV A E G+ WH CF C KC +L + + ++YC
Sbjct: 236 KCAGCKNPITGFGKGSSVVAYE-----GQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCP 290
Query: 169 GCYAK 173
C K
Sbjct: 291 DCAKK 295
Score = 47.0 bits (110), Expect = 1e-05
Identities = 32/105 (30%), Positives = 40/105 (38%), Gaps = 14/105 (13%)
Query: 87 RLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYA-----AEKIIGAGKP--- 138
++G E H K+ QK G C +C D A K IGA
Sbjct: 13 KVGTMAEKFDCHYCRDPLQGKKYVQK-DGHHCCLKCFDKFCANTCVECRKPIGADSKEVH 71
Query: 139 -----WHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
WH CFRCAKC L + T K+ +I C C + PK
Sbjct: 72 YKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPK 116
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 65.5 bits (158), Expect = 3e-11
Identities = 56/206 (27%), Positives = 82/206 (39%), Gaps = 25/206 (12%)
Query: 8 NKCGACGRTV-YHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C C + + ++EV R +H CF C C L + T D +I C C ++
Sbjct: 38 NTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTRED 97
Query: 67 GPKGYGYGQG--AGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGD 124
PK G + AG N++ + K + T F K G C C +
Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHK-DCFTCSNCKQVIGTGSFFPK-GEDFYCVTCHE 155
Query: 125 SVYA-----AEKIIGAG------KPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAK 173
+ +A K I +G +PWH +CF C C K L T E + YC CY K
Sbjct: 156 TKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY-K 214
Query: 174 NFGPKG--------FGYGQGAGALVH 191
NF K G+G+G+ + +
Sbjct: 215 NFVAKKCAGCKNPITGFGKGSSVVAY 240
Score = 53.1 bits (126), Expect = 1e-07
Identities = 42/185 (22%), Positives = 70/185 (37%), Gaps = 25/185 (13%)
Query: 9 KCGACGRTVYHAEE-VQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYG 67
KC C + + ++ V+ G +H+ CF C C++ + + + E+ YC +C+ K+
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
Query: 68 PKGYGYGQG---AGTLNMDRGERLGI-------KPESVQPHRPTTNPNTSKFAQKYGGAE 117
+ G D+ K + Q + K A+
Sbjct: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
Query: 118 KCSRC---------GDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK 168
KC+ C G SV A E G+ WH CF C KC +L + + ++YC
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYE-----GQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCP 274
Query: 169 GCYAK 173
C K
Sbjct: 275 DCAKK 279
Score = 46.6 bits (109), Expect = 1e-05
Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 14/84 (16%)
Query: 108 KFAQKYGGAEKCSRCGDSVYA-----AEKIIGAGKP--------WHKNCFRCAKCGKSLE 154
K+ QK G C +C D A K IGA WH CFRCAKC L
Sbjct: 18 KYVQK-DGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLA 76
Query: 155 STTLTEKEGEIYCKGCYAKNFGPK 178
+ T K+ +I C C + PK
Sbjct: 77 NETFVAKDNKILCNKCTTREDSPK 100
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 64.3 bits (155), Expect = 6e-11
Identities = 53/185 (28%), Positives = 74/185 (40%), Gaps = 17/185 (9%)
Query: 8 NKCGACGRTV-YHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKY 66
N C C + + ++EV R +H CF C C L + T D +I C C ++
Sbjct: 38 NTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTRED 97
Query: 67 GPKGYGYGQG--AGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGD 124
PK G + AG N++ + K + T F K G C C +
Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHK-DCFTCSNCKQVIGTGSFFPK-GEDFYCVTCHE 155
Query: 125 SVYA-----AEKIIGAG------KPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAK 173
+ +A K I +G +PWH +CF C C K L T E + YC CY K
Sbjct: 156 TKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY-K 214
Query: 174 NFGPK 178
NF K
Sbjct: 215 NFVAK 219
Score = 46.6 bits (109), Expect = 1e-05
Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 14/84 (16%)
Query: 108 KFAQKYGGAEKCSRCGDSVYA-----AEKIIGAGKP--------WHKNCFRCAKCGKSLE 154
K+ QK G C +C D A K IGA WH CFRCAKC L
Sbjct: 18 KYVQK-DGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLA 76
Query: 155 STTLTEKEGEIYCKGCYAKNFGPK 178
+ T K+ +I C C + PK
Sbjct: 77 NETFVAKDNKILCNKCTTREDSPK 100
Score = 35.0 bits (79), Expect = 0.040
Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 17/89 (19%)
Query: 10 CGACGRTVYHAEEVQCD-----------GRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYC 58
C C T + V+C+ + +H CF+C+ C K L +++ YC
Sbjct: 150 CVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
Query: 59 KSCYGKKYGPKGYGYGQGAGTLNMDRGER 87
CY K + + AG N G+R
Sbjct: 210 VDCY------KNFVAKKCAGCKNPITGKR 232
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 63.2 bits (152), Expect = 1e-10
Identities = 42/173 (24%), Positives = 64/173 (36%), Gaps = 44/173 (25%)
Query: 7 GNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNL-DSTTVAIHDEEIYCKSCYGKK 65
G +C CG V E V G+++H CF C +C++ V + + C+ C
Sbjct: 95 GTRCHGCGEFV-EGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLC---- 149
Query: 66 YGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDS 125
+P S P T + N C+ CG
Sbjct: 150 ------------------------AQPMSSSPKETTFSSN-------------CAGCGRD 172
Query: 126 VYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
+ + ++ K WH CF+C CGK L ++ K+G YC+ Y FG K
Sbjct: 173 IKNGQALLALDKQWHLGCFKCKSCGKVLTGEYIS-KDGAPYCEKDYQGLFGVK 224
Score = 37.4 bits (85), Expect = 0.008
Identities = 24/88 (27%), Positives = 33/88 (37%), Gaps = 12/88 (13%)
Query: 97 PHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLEST 156
PH P+ P C +CG+ E + K +H CF C CG L
Sbjct: 28 PHHPSEKP-----------VIHCHKCGEPC-KGEVLRVQTKHFHIKCFTCKVCGCDLAQG 75
Query: 157 TLTEKEGEIYCKGCYAKNFGPKGFGYGQ 184
K GE C Y + +G + G G+
Sbjct: 76 GFFIKNGEYLCTLDYQRMYGTRCHGCGE 103
Score = 35.8 bits (81), Expect = 0.023
Identities = 31/140 (22%), Positives = 41/140 (29%), Gaps = 51/140 (36%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPK 69
C CG E ++ + FH CF C VC +L I + E C Y + YG
Sbjct: 39 CHKCGEPC-KGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGT- 96
Query: 70 GYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAA 129
+C CG+ V
Sbjct: 97 ------------------------------------------------RCHGCGEFV-EG 107
Query: 130 EKIIGAGKPWHKNCFRCAKC 149
E + GK +H NCF C C
Sbjct: 108 EVVTALGKTYHPNCFACTIC 127
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 63.2 bits (152), Expect = 1e-10
Identities = 42/173 (24%), Positives = 64/173 (36%), Gaps = 44/173 (25%)
Query: 7 GNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNL-DSTTVAIHDEEIYCKSCYGKK 65
G +C CG V E V G+++H CF C +C++ V + + C+ C
Sbjct: 95 GTRCHGCGEFV-EGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLC---- 149
Query: 66 YGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDS 125
+P S P T + N C+ CG
Sbjct: 150 ------------------------AQPMSSSPKETTFSSN-------------CAGCGRD 172
Query: 126 VYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
+ + ++ K WH CF+C CGK L ++ K+G YC+ Y FG K
Sbjct: 173 IKNGQALLALDKQWHLGCFKCKSCGKVLTGEYIS-KDGAPYCEKDYQGLFGVK 224
Score = 39.7 bits (91), Expect = 0.002
Identities = 31/150 (20%), Positives = 53/150 (35%), Gaps = 25/150 (16%)
Query: 8 NKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYG 67
+ C CGR + + + + + +H CF C C K L ++ D YC+ Y +G
Sbjct: 164 SNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYIS-KDGAPYCEKDYQGLFG 222
Query: 68 PKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVY 127
K Q ++ G++ + +CSRC
Sbjct: 223 VKCEACHQFITGKVLEAGDK-----------------------HYHPSCARCSRCNQMFT 259
Query: 128 AAEKIIGAGKP-WHKNCFRCAKCGKSLEST 156
E++ G WH +C + K + L T
Sbjct: 260 EGEEMYLQGSTVWHPDCKQSTKTEEKLRPT 289
Score = 37.4 bits (85), Expect = 0.008
Identities = 24/88 (27%), Positives = 33/88 (37%), Gaps = 12/88 (13%)
Query: 97 PHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLEST 156
PH P+ P C +CG+ E + K +H CF C CG L
Sbjct: 28 PHHPSEKP-----------VIHCHKCGEPC-KGEVLRVQTKHFHIKCFTCKVCGCDLAQG 75
Query: 157 TLTEKEGEIYCKGCYAKNFGPKGFGYGQ 184
K GE C Y + +G + G G+
Sbjct: 76 GFFIKNGEYLCTLDYQRMYGTRCHGCGE 103
Score = 35.8 bits (81), Expect = 0.023
Identities = 31/140 (22%), Positives = 41/140 (29%), Gaps = 51/140 (36%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPK 69
C CG E ++ + FH CF C VC +L I + E C Y + YG
Sbjct: 39 CHKCGEPC-KGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGT- 96
Query: 70 GYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAA 129
+C CG+ V
Sbjct: 97 ------------------------------------------------RCHGCGEFV-EG 107
Query: 130 EKIIGAGKPWHKNCFRCAKC 149
E + GK +H NCF C C
Sbjct: 108 EVVTALGKTYHPNCFACTIC 127
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 63.2 bits (152), Expect = 1e-10
Identities = 42/173 (24%), Positives = 64/173 (36%), Gaps = 44/173 (25%)
Query: 7 GNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNL-DSTTVAIHDEEIYCKSCYGKK 65
G +C CG V E V G+++H CF C +C++ V + + C+ C
Sbjct: 155 GTRCHGCGEFV-EGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLC---- 209
Query: 66 YGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDS 125
+P S P T + N C+ CG
Sbjct: 210 ------------------------AQPMSSSPKETTFSSN-------------CAGCGRD 232
Query: 126 VYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
+ + ++ K WH CF+C CGK L ++ K+G YC+ Y FG K
Sbjct: 233 IKNGQALLALDKQWHLGCFKCKSCGKVLTGEYIS-KDGAPYCEKDYQGLFGVK 284
Score = 39.7 bits (91), Expect = 0.002
Identities = 31/150 (20%), Positives = 53/150 (35%), Gaps = 25/150 (16%)
Query: 8 NKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYG 67
+ C CGR + + + + + +H CF C C K L ++ D YC+ Y +G
Sbjct: 224 SNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYIS-KDGAPYCEKDYQGLFG 282
Query: 68 PKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVY 127
K Q ++ G++ + +CSRC
Sbjct: 283 VKCEACHQFITGKVLEAGDK-----------------------HYHPSCARCSRCNQMFT 319
Query: 128 AAEKIIGAGKP-WHKNCFRCAKCGKSLEST 156
E++ G WH +C + K + L T
Sbjct: 320 EGEEMYLQGSTVWHPDCKQSTKTEEKLRPT 349
Score = 37.4 bits (85), Expect = 0.008
Identities = 24/88 (27%), Positives = 33/88 (37%), Gaps = 12/88 (13%)
Query: 97 PHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLEST 156
PH P+ P C +CG+ E + K +H CF C CG L
Sbjct: 88 PHHPSEKP-----------VIHCHKCGEPC-KGEVLRVQTKHFHIKCFTCKVCGCDLAQG 135
Query: 157 TLTEKEGEIYCKGCYAKNFGPKGFGYGQ 184
K GE C Y + +G + G G+
Sbjct: 136 GFFIKNGEYLCTLDYQRMYGTRCHGCGE 163
Score = 35.8 bits (81), Expect = 0.023
Identities = 31/140 (22%), Positives = 41/140 (29%), Gaps = 51/140 (36%)
Query: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPK 69
C CG E ++ + FH CF C VC +L I + E C Y + YG
Sbjct: 99 CHKCGEPC-KGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGT- 156
Query: 70 GYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAA 129
+C CG+ V
Sbjct: 157 ------------------------------------------------RCHGCGEFV-EG 167
Query: 130 EKIIGAGKPWHKNCFRCAKC 149
E + GK +H NCF C C
Sbjct: 168 EVVTALGKTYHPNCFACTIC 187
>gi|7662330 actin binding LIM protein family, member 3 [Homo
sapiens]
Length = 683
Score = 60.1 bits (144), Expect = 1e-09
Identities = 40/173 (23%), Positives = 65/173 (37%), Gaps = 43/173 (24%)
Query: 7 GNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLD-STTVAIHDEEIYCKSCYGKK 65
G +C +C R E + GR++H CF+C +CRK V +E C++C
Sbjct: 79 GTRCDSC-RDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTC---- 133
Query: 66 YGPKGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDS 125
+S+ +P K G C+ C +
Sbjct: 134 --------------------------SQSMASSKPI----------KIRGPSHCAGCKEE 157
Query: 126 VYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPK 178
+ + ++ K WH +CF+C C L ++ K+G YC+ Y FG K
Sbjct: 158 IKHGQSLLALDKQWHVSCFKCQTCSVILTGEYIS-KDGVPYCESDYHAQFGIK 209
Score = 36.6 bits (83), Expect = 0.014
Identities = 36/163 (22%), Positives = 49/163 (30%), Gaps = 52/163 (31%)
Query: 9 KCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGP 68
+C CG T E V+ FH CF C VC L + ++E C
Sbjct: 22 QCYRCGDTC-KGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYIC---------- 70
Query: 69 KGYGYGQGAGTLNMDRGERLGIKPESVQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYA 128
T + Q YG +C C D +
Sbjct: 71 -------------------------------------TQDYQQLYG--TRCDSCRDFI-T 90
Query: 129 AEKIIGAGKPWHKNCFRCAKCGKSLE-STTLTEKEGEIYCKGC 170
E I G+ +H CF C+ C K +T E C+ C
Sbjct: 91 GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTC 133
Score = 33.5 bits (75), Expect = 0.12
Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Query: 118 KCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGP 177
+C RCGD+ E + +H CF C CG L + K E C Y + +G
Sbjct: 22 QCYRCGDTC-KGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGT 80
Query: 178 K 178
+
Sbjct: 81 R 81
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.464
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,189,737
Number of Sequences: 37866
Number of extensions: 468183
Number of successful extensions: 2602
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 1732
Number of HSP's gapped (non-prelim): 930
length of query: 193
length of database: 18,247,518
effective HSP length: 97
effective length of query: 96
effective length of database: 14,574,516
effective search space: 1399153536
effective search space used: 1399153536
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.