Guide to the Human Genome
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Search of human proteins with 4503053

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503053 hyaluronan and proteoglycan link protein 1 [Homo
sapiens]
         (354 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503053 hyaluronan and proteoglycan link protein 1 [Homo sapi...   751   0.0  
gi|30102948 hyaluronan and proteoglycan link protein 3 [Homo sap...   375   e-104
gi|30794472 hyaluronan and proteoglycan link protein 4 [Homo sap...   353   1e-97
gi|11141887 brain link protein-1 [Homo sapiens]                       313   1e-85
gi|38372931 brevican isoform 2 [Homo sapiens]                         224   7e-59
gi|38372935 brevican isoform 1 [Homo sapiens]                         224   7e-59
gi|187607300 versican isoform 2 [Homo sapiens]                        217   1e-56
gi|21361116 versican isoform 1 [Homo sapiens]                         217   1e-56
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]              212   4e-55
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]              212   4e-55
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]        210   2e-54
gi|61743978 stabilin 1 precursor [Homo sapiens]                        66   4e-11
gi|61743980 stabilin 2 precursor [Homo sapiens]                        65   7e-11
gi|26051243 tumor necrosis factor, alpha-induced protein 6 precu...    63   5e-10
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]     45   8e-05
gi|40549451 lymphatic vessel endothelial hyaluronan receptor 1 [...    43   5e-04
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho...    40   0.002
gi|154426280 V-set and immunoglobulin domain containing 4 isofor...    39   0.005
gi|6005958 V-set and immunoglobulin domain containing 4 isoform ...    39   0.005
gi|11386199 poliovirus receptor-related 3 [Homo sapiens]               39   0.009
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s...    35   0.078
gi|9055238 voltage-gated sodium channel beta-3 subunit precursor...    33   0.39 
gi|93587332 voltage-gated sodium channel beta-3 subunit precurso...    33   0.39 
gi|148664224 adhesion molecule, interacts with CXADR antigen 1 i...    33   0.51 
gi|148664207 adhesion molecule, interacts with CXADR antigen 1 i...    33   0.51 
gi|63054855 erythroblast membrane-associated protein precursor [...    32   0.66 
gi|19923536 erythroblast membrane-associated protein precursor [...    32   0.66 
gi|110349719 titin isoform N2-A [Homo sapiens]                         32   0.86 
gi|110349717 titin isoform novex-2 [Homo sapiens]                      32   0.86 
gi|110349713 titin isoform novex-1 [Homo sapiens]                      32   0.86 

>gi|4503053 hyaluronan and proteoglycan link protein 1 [Homo
           sapiens]
          Length = 354

 Score =  751 bits (1938), Expect = 0.0
 Identities = 354/354 (100%), Positives = 354/354 (100%)

Query: 1   MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLP 60
           MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLP
Sbjct: 1   MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLP 60

Query: 61  CKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDS 120
           CKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDS
Sbjct: 61  CKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDS 120

Query: 121 DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQA 180
           DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQA
Sbjct: 121 DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQA 180

Query: 181 CLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF 240
           CLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF
Sbjct: 181 CLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF 240

Query: 241 WDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILG 300
           WDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILG
Sbjct: 241 WDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILG 300

Query: 301 YDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN 354
           YDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN
Sbjct: 301 YDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN 354


>gi|30102948 hyaluronan and proteoglycan link protein 3 [Homo
           sapiens]
          Length = 360

 Score =  375 bits (963), Expect = e-104
 Identities = 175/318 (55%), Positives = 220/318 (69%), Gaps = 2/318 (0%)

Query: 36  NGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVF 95
           NG  L+VE  +  +F+++G +V LPC++  +P        ++R+KW KL+ +   E DV 
Sbjct: 45  NGVKLVVETPEETLFTYQGASVILPCRYRYEPALVSP--RRVRVKWWKLSENGAPEKDVL 102

Query: 96  VSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALD 155
           V++G   +++G YQGRV L+   + D SL I DL LEDYGRY+CEVI+GLED++ +V L+
Sbjct: 103 VAIGLRHRSFGDYQGRVHLRQDKEHDVSLEIQDLRLEDYGRYRCEVIDGLEDESGLVELE 162

Query: 156 LQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSV 215
           L+GVVFPY    GRY  NFHE QQ C +Q AV+ASF+QL+ AW  GLDWCNAGWL D +V
Sbjct: 163 LRGVVFPYQSPNGRYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATV 222

Query: 216 QYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEA 275
           QYPI  PR+PCGG    PGVR+YG   +   RYDVFCF +   GR YYL HP KLT  EA
Sbjct: 223 QYPIMLPRQPCGGPGLAPGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEA 282

Query: 276 VQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV 335
            +AC  D A IAKVGQ+FAAWK  G DRCDAGWLADGSVRYP+  P   C P E  VR  
Sbjct: 283 REACQEDDATIAKVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSF 342

Query: 336 GFPDKKHKLYGVYCFRAY 353
           GFPD + +LYGVYC+R +
Sbjct: 343 GFPDPQSRLYGVYCYRQH 360


>gi|30794472 hyaluronan and proteoglycan link protein 4 [Homo
           sapiens]
          Length = 402

 Score =  353 bits (906), Expect = 1e-97
 Identities = 169/335 (50%), Positives = 221/335 (65%), Gaps = 13/335 (3%)

Query: 28  RAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSD 87
           + +H+       ++V+    +V SHRGG + LPC+++ +  A G     +R+KWTK+  D
Sbjct: 35  KVVHVLEGESGSVVVQTAPGQVVSHRGGTIVLPCRYHYEAAAHGHD--GVRLKWTKVV-D 91

Query: 88  YLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLED 147
            L   DVFV++G   + +G Y+GR  L+G    DASLV+ ++TL+DYGRY+CEV   LED
Sbjct: 92  PLAFTDVFVALGPQHRAFGSYRGRAELQGDGPGDASLVLRNVTLQDYGRYECEVTNELED 151

Query: 148 DTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNA 207
           D  +V LDL+GVVFPY PR GRY L F EAQ+AC +QD ++AS +QL+ AWR GLDWCNA
Sbjct: 152 DAGMVKLDLEGVVFPYHPRGGRYKLTFAEAQRACAEQDGILASAEQLHAAWRDGLDWCNA 211

Query: 208 GWLSDGSVQYPITKPREPC----------GGQNTVPGVRNYGFWDKDKSRYDVFCFTSNF 257
           GWL DGSVQYP+ +PREPC          GG +   G+RNYG+    + RYD FCFTSN 
Sbjct: 212 GWLRDGSVQYPVNRPREPCGGLGGTGSAGGGGDANGGLRNYGYRHNAEERYDAFCFTSNL 271

Query: 258 NGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYP 317
            GR ++L     + +  A +AC   GA +AKVGQ+FAAWK+   DRC AGWLADGS RYP
Sbjct: 272 PGRVFFLKPLRPVPFSGAARACAARGAAVAKVGQLFAAWKLQLLDRCTAGWLADGSARYP 331

Query: 318 ISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRA 352
           I  PR RC      VR +GFPD   +L+GVYC+RA
Sbjct: 332 IVNPRARCGGRRPGVRSLGFPDATRRLFGVYCYRA 366


>gi|11141887 brain link protein-1 [Homo sapiens]
          Length = 340

 Score =  313 bits (803), Expect = 1e-85
 Identities = 151/330 (45%), Positives = 207/330 (62%), Gaps = 11/330 (3%)

Query: 22  YTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKW 81
           +T+ H       +  GPH L+      + SHRG   TLPC     P ++       +++W
Sbjct: 18  FTIFHKAQGDPASHPGPHYLLPPIHEVIHSHRGATATLPCVLGTTPPSY-------KVRW 70

Query: 82  TKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEV 141
           +K+    L+E  + ++ G H + YG   GR  ++ G   DASLVI  + LED GRY+CE+
Sbjct: 71  SKVEPGELRETLILITNGLHARGYGPLGGRARMRRGHRLDASLVIAGVRLEDEGRYRCEL 130

Query: 142 IEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGG 201
           I G+ED++V + L L+GVVFPY P  GRY  N++EA+QAC +QD  +A++ QLY AW  G
Sbjct: 131 INGIEDESVALTLSLEGVVFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEG 190

Query: 202 LDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRF 261
           LDWCNAGWL +GSV+YP+   R PCGG+   PG+R+YG  D+ + RYD FCFTS   G+ 
Sbjct: 191 LDWCNAGWLLEGSVRYPVLTARAPCGGRGR-PGIRSYGPRDRMRDRYDAFCFTSALAGQV 249

Query: 262 YYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRP 321
           +++  P +LT  EA  AC   GA +AKVG ++AAWK  G D+CD GWLADGSVR+PI+ P
Sbjct: 250 FFV--PGRLTLSEAHAACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTP 307

Query: 322 RRRCSP-TEAAVRFVGFPDKKHKLYGVYCF 350
           R RC    +  VR  GFP  +   YG YC+
Sbjct: 308 RPRCGGLPDPGVRSFGFPRPQQAAYGTYCY 337



 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 40/86 (46%), Positives = 53/86 (61%), Gaps = 2/86 (2%)

Query: 172 LNFHEAQQACLDQDAVIASFDQLYDAWR-GGLDWCNAGWLSDGSVQYPITKPREPCGGQN 230
           L   EA  AC  + AV+A    LY AW+  GLD C+ GWL+DGSV++PIT PR  CGG  
Sbjct: 256 LTLSEAHAACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLP 315

Query: 231 TVPGVRNYGFWDKDKSRYDVFCFTSN 256
             PGVR++GF    ++ Y  +C+  N
Sbjct: 316 D-PGVRSFGFPRPQQAAYGTYCYAEN 340


>gi|38372931 brevican isoform 2 [Homo sapiens]
          Length = 671

 Score =  224 bits (572), Expect = 7e-59
 Identities = 132/310 (42%), Positives = 178/310 (57%), Gaps = 17/310 (5%)

Query: 54  GGNVTLPCK--FYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGR 111
           GG +T+PC   + R P +  + +   R+KWT L+    +E +V V+ G   K    Y+ R
Sbjct: 50  GGALTIPCHVHYLRPPPSRRAVLGSPRVKWTFLSRG--REAEVLVARGVRVKVNEAYRFR 107

Query: 112 VFLKG--GSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGR 169
           V L     S +D SL +++L   D G Y+CEV  G++D +  V + ++GVVF Y     R
Sbjct: 108 VALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSAR 167

Query: 170 YNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPC-GG 228
           Y  +F  AQ+AC    A IA+ +QLY A+ GG + C+AGWLSD +V+YPI  PRE C G 
Sbjct: 168 YAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGD 227

Query: 229 QNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAK 288
            +  PGVRNYG  D D   YDV+C+  + NG  +    P KLT +EA   C   GA+IA 
Sbjct: 228 MDGFPGVRNYGVVDPD-DLYDVYCYAEDLNGELFLGDPPEKLTLEEARAYCQERGAEIAT 286

Query: 289 VGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV-------GFPDKK 341
            GQ++AAW   G D C  GWLADGSVRYPI  P +RC      V+ +       GFP+ K
Sbjct: 287 TGQLYAAWD-GGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPN-K 344

Query: 342 HKLYGVYCFR 351
           H  + VYCFR
Sbjct: 345 HSRFNVYCFR 354


>gi|38372935 brevican isoform 1 [Homo sapiens]
          Length = 911

 Score =  224 bits (572), Expect = 7e-59
 Identities = 132/310 (42%), Positives = 178/310 (57%), Gaps = 17/310 (5%)

Query: 54  GGNVTLPCK--FYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGR 111
           GG +T+PC   + R P +  + +   R+KWT L+    +E +V V+ G   K    Y+ R
Sbjct: 50  GGALTIPCHVHYLRPPPSRRAVLGSPRVKWTFLSRG--REAEVLVARGVRVKVNEAYRFR 107

Query: 112 VFLKG--GSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGR 169
           V L     S +D SL +++L   D G Y+CEV  G++D +  V + ++GVVF Y     R
Sbjct: 108 VALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSAR 167

Query: 170 YNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPC-GG 228
           Y  +F  AQ+AC    A IA+ +QLY A+ GG + C+AGWLSD +V+YPI  PRE C G 
Sbjct: 168 YAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGD 227

Query: 229 QNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAK 288
            +  PGVRNYG  D D   YDV+C+  + NG  +    P KLT +EA   C   GA+IA 
Sbjct: 228 MDGFPGVRNYGVVDPD-DLYDVYCYAEDLNGELFLGDPPEKLTLEEARAYCQERGAEIAT 286

Query: 289 VGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV-------GFPDKK 341
            GQ++AAW   G D C  GWLADGSVRYPI  P +RC      V+ +       GFP+ K
Sbjct: 287 TGQLYAAWD-GGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPN-K 344

Query: 342 HKLYGVYCFR 351
           H  + VYCFR
Sbjct: 345 HSRFNVYCFR 354


>gi|187607300 versican isoform 2 [Homo sapiens]
          Length = 655

 Score =  217 bits (553), Expect = 1e-56
 Identities = 126/313 (40%), Positives = 182/313 (58%), Gaps = 19/313 (6%)

Query: 55  GNVTLPCKFYRDPTAFGS--GIHKIRIKWTKLTSDY----LKEVDVFVSMGYHKKTYGGY 108
           G V+LPC F   PT   S      +RIKW+K+  D     LKE  V V+   + K    Y
Sbjct: 38  GKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDY 97

Query: 109 QGRVFLKGGSDS--DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPR 166
           +GRV +    ++  DASL +  L   D G Y+C+V+ G+ED    V+L + GVVF Y   
Sbjct: 98  KGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAA 157

Query: 167 LGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPC 226
             RY LNF  AQ+ACLD  AVIA+ +QL+ A+  G + C+AGWL+D +V+YPI  PR  C
Sbjct: 158 TSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGC 217

Query: 227 -GGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQ 285
            G +    GVR YGF    ++ YDV+C+  + +G  ++L  P+K T++EA + C N  A+
Sbjct: 218 YGDKMGKAGVRTYGFRSPQET-YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDAR 276

Query: 286 IAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV-------GFP 338
           +A VG++ AAW+  G+D+CD GWL+D SVR+P++  R +C      VR +       GFP
Sbjct: 277 LATVGELQAAWR-NGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFP 335

Query: 339 DKKHKLYGVYCFR 351
               + +  YCF+
Sbjct: 336 PPDSR-FDAYCFK 347


>gi|21361116 versican isoform 1 [Homo sapiens]
          Length = 3396

 Score =  217 bits (553), Expect = 1e-56
 Identities = 126/313 (40%), Positives = 182/313 (58%), Gaps = 19/313 (6%)

Query: 55  GNVTLPCKFYRDPTAFGS--GIHKIRIKWTKLTSDY----LKEVDVFVSMGYHKKTYGGY 108
           G V+LPC F   PT   S      +RIKW+K+  D     LKE  V V+   + K    Y
Sbjct: 38  GKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDY 97

Query: 109 QGRVFLKGGSDS--DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPR 166
           +GRV +    ++  DASL +  L   D G Y+C+V+ G+ED    V+L + GVVF Y   
Sbjct: 98  KGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAA 157

Query: 167 LGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPC 226
             RY LNF  AQ+ACLD  AVIA+ +QL+ A+  G + C+AGWL+D +V+YPI  PR  C
Sbjct: 158 TSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGC 217

Query: 227 -GGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQ 285
            G +    GVR YGF    ++ YDV+C+  + +G  ++L  P+K T++EA + C N  A+
Sbjct: 218 YGDKMGKAGVRTYGFRSPQET-YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDAR 276

Query: 286 IAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV-------GFP 338
           +A VG++ AAW+  G+D+CD GWL+D SVR+P++  R +C      VR +       GFP
Sbjct: 277 LATVGELQAAWR-NGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFP 335

Query: 339 DKKHKLYGVYCFR 351
               + +  YCF+
Sbjct: 336 PPDSR-FDAYCFK 347


>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
          Length = 2416

 Score =  212 bits (540), Expect = 4e-55
 Identities = 129/343 (37%), Positives = 182/343 (53%), Gaps = 30/343 (8%)

Query: 23  TLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDP-----TAFGSGIHKI 77
           T DHD ++ +       L V           G ++T+PC F  DP     TA  +     
Sbjct: 22  TSDHDNSLSVSIPQPSPLRVLL---------GTSLTIPCYFI-DPMHPVTTAPSTAPLAP 71

Query: 78  RIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKG--GSDSDASLVITDLTLEDYG 135
           RIKW++++ +  KEV + V+     +    YQ +V L       SDA+L +  L   D G
Sbjct: 72  RIKWSRVSKE--KEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSG 129

Query: 136 RYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLY 195
            Y+CEV+ G+ED    + + ++G+VF Y     RY L+F  AQ+ACL   A+IA+ +QL 
Sbjct: 130 VYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQ 189

Query: 196 DAWRGGLDWCNAGWLSDGSVQYPITKPREPC-GGQNTVPGVRNYGFWDKDKSRYDVFCFT 254
            A+  G   C+AGWL+D +V+YPI  PRE C G ++  PGVR YG  D +++ YDV+CF 
Sbjct: 190 AAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNET-YDVYCFA 248

Query: 255 SNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSV 314
               G  +Y   P K T+ EA   C   GA++A  GQ++ AW+  G D C AGWLAD SV
Sbjct: 249 EEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQ-AGMDMCSAGWLADRSV 307

Query: 315 RYPISRPRRRCSPTEAAVRFV-------GFPDKKHKLYGVYCF 350
           RYPIS+ R  C      VR V       G+PD   + Y   C+
Sbjct: 308 RYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSR-YDAICY 349



 Score =  169 bits (429), Expect = 3e-42
 Identities = 91/202 (45%), Positives = 120/202 (59%), Gaps = 11/202 (5%)

Query: 158 GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQY 217
           GVVF Y P   RY+L F EAQQACL   AVIAS +QL  A+  G + C+AGWL D +V+Y
Sbjct: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536

Query: 218 PITKPREPC-GGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAV 276
           PI  PR PC G +++ PGVR YG     ++ YDV+CF     G  ++     + T+ EA+
Sbjct: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTET-YDVYCFVDRLEGEVFFATRLEQFTFQEAL 595

Query: 277 QACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV- 335
           + C +  A +A  GQ++AAW   G D+C AGWLADGS+RYPI  PR  C   +  VR V 
Sbjct: 596 EFCESHNATLATTGQLYAAWS-RGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVY 654

Query: 336 ------GFPDKKHKLYGVYCFR 351
                 G PD   + +  +CFR
Sbjct: 655 LYPNQTGLPDPLSR-HHAFCFR 675



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 44/111 (39%), Positives = 59/111 (53%), Gaps = 7/111 (6%)

Query: 148 DTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNA 207
           D    A +++G VF Y     ++   F EA   C    A +A+  QLY AW+ G+D C+A
Sbjct: 243 DVYCFAEEMEGEVF-YATSPEKFT--FQEAANECRRLGARLATTGQLYLAWQAGMDMCSA 299

Query: 208 GWLSDGSVQYPITKPREPCGGQ----NTVPGVRNYGFWDKDKSRYDVFCFT 254
           GWL+D SV+YPI+K R  CGG      TV    N   +    SRYD  C+T
Sbjct: 300 GWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYT 350


>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
          Length = 2317

 Score =  212 bits (540), Expect = 4e-55
 Identities = 129/343 (37%), Positives = 182/343 (53%), Gaps = 30/343 (8%)

Query: 23  TLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDP-----TAFGSGIHKI 77
           T DHD ++ +       L V           G ++T+PC F  DP     TA  +     
Sbjct: 22  TSDHDNSLSVSIPQPSPLRVLL---------GTSLTIPCYFI-DPMHPVTTAPSTAPLAP 71

Query: 78  RIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKG--GSDSDASLVITDLTLEDYG 135
           RIKW++++ +  KEV + V+     +    YQ +V L       SDA+L +  L   D G
Sbjct: 72  RIKWSRVSKE--KEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSG 129

Query: 136 RYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLY 195
            Y+CEV+ G+ED    + + ++G+VF Y     RY L+F  AQ+ACL   A+IA+ +QL 
Sbjct: 130 VYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQ 189

Query: 196 DAWRGGLDWCNAGWLSDGSVQYPITKPREPC-GGQNTVPGVRNYGFWDKDKSRYDVFCFT 254
            A+  G   C+AGWL+D +V+YPI  PRE C G ++  PGVR YG  D +++ YDV+CF 
Sbjct: 190 AAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNET-YDVYCFA 248

Query: 255 SNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSV 314
               G  +Y   P K T+ EA   C   GA++A  GQ++ AW+  G D C AGWLAD SV
Sbjct: 249 EEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQ-AGMDMCSAGWLADRSV 307

Query: 315 RYPISRPRRRCSPTEAAVRFV-------GFPDKKHKLYGVYCF 350
           RYPIS+ R  C      VR V       G+PD   + Y   C+
Sbjct: 308 RYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSR-YDAICY 349



 Score =  169 bits (429), Expect = 3e-42
 Identities = 91/202 (45%), Positives = 120/202 (59%), Gaps = 11/202 (5%)

Query: 158 GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQY 217
           GVVF Y P   RY+L F EAQQACL   AVIAS +QL  A+  G + C+AGWL D +V+Y
Sbjct: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536

Query: 218 PITKPREPC-GGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAV 276
           PI  PR PC G +++ PGVR YG     ++ YDV+CF     G  ++     + T+ EA+
Sbjct: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTET-YDVYCFVDRLEGEVFFATRLEQFTFQEAL 595

Query: 277 QACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV- 335
           + C +  A +A  GQ++AAW   G D+C AGWLADGS+RYPI  PR  C   +  VR V 
Sbjct: 596 EFCESHNATLATTGQLYAAWS-RGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVY 654

Query: 336 ------GFPDKKHKLYGVYCFR 351
                 G PD   + +  +CFR
Sbjct: 655 LYPNQTGLPDPLSR-HHAFCFR 675



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 44/111 (39%), Positives = 59/111 (53%), Gaps = 7/111 (6%)

Query: 148 DTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNA 207
           D    A +++G VF Y     ++   F EA   C    A +A+  QLY AW+ G+D C+A
Sbjct: 243 DVYCFAEEMEGEVF-YATSPEKFT--FQEAANECRRLGARLATTGQLYLAWQAGMDMCSA 299

Query: 208 GWLSDGSVQYPITKPREPCGGQ----NTVPGVRNYGFWDKDKSRYDVFCFT 254
           GWL+D SV+YPI+K R  CGG      TV    N   +    SRYD  C+T
Sbjct: 300 GWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYT 350


>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
          Length = 1321

 Score =  210 bits (534), Expect = 2e-54
 Identities = 135/363 (37%), Positives = 194/363 (53%), Gaps = 25/363 (6%)

Query: 4   LLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKF 63
           LL+L ++     +  + + T   +R +H+Q        V+A  A++       V LPC F
Sbjct: 11  LLMLQMLLFVAGEQGTQDITDASERGLHMQKLGSGS--VQAALAEL-------VALPCLF 61

Query: 64  YRDPTAFGSGIHKIRIKWTKL--TSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKG--GSD 119
              P    +     RIKWTK+   S   +++ + V+     +    +QGRV L       
Sbjct: 62  TLQPRP-SAARDAPRIKWTKVRTASGQRQDLPILVAKDNVVRVAKSWQGRVSLPSYPRRR 120

Query: 120 SDASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQ 179
           ++A+L++  L   D G Y+C+V+ G+ED+  +V L++ GVVF Y     RY L F EAQ+
Sbjct: 121 ANATLLLGPLRASDSGLYRCQVVRGIEDEQDLVPLEVTGVVFHYRSARDRYALTFAEAQE 180

Query: 180 ACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPC-GGQNTVPGVRNY 238
           AC    A+IA+   L  A+  G D C+AGWLSD +V+YPIT+ R  C G ++++PGVR+Y
Sbjct: 181 ACRLSSAIIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYPITQSRPGCYGDRSSLPGVRSY 240

Query: 239 GFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKI 298
           G     +  YDV+CF     G  +Y+    +LT   A   C   GA +A VGQ+  AW  
Sbjct: 241 G-RRNPQELYDVYCFARELGGEVFYVGPARRLTLAGARAQCRRQGAALASVGQLHLAWH- 298

Query: 299 LGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV-------GFPDKKHKLYGVYCFR 351
            G D+CD GWLADGSVRYPI  PRRRC      VR V       GFP    + +  YCFR
Sbjct: 299 EGLDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRFANRTGFPSPAER-FDAYCFR 357

Query: 352 AYN 354
           A++
Sbjct: 358 AHH 360


>gi|61743978 stabilin 1 precursor [Homo sapiens]
          Length = 2570

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 36/86 (41%), Positives = 47/86 (54%), Gaps = 2/86 (2%)

Query: 168  GRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCG 227
            G Y LNF EA+ AC  Q AV+ASF QL  A + G   C  GWL++GS  +P+  P   CG
Sbjct: 2217 GPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCG 2276

Query: 228  GQNTVPGVRNYGFWDKDKSRYDVFCF 253
              N   G+ + G       R+D +CF
Sbjct: 2277 --NGRVGIVSLGARKNLSERWDAYCF 2300



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 42/154 (27%), Positives = 63/154 (40%), Gaps = 21/154 (13%)

Query: 205  CNAGWLSDGSVQYPITKPR-EPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYY 263
            C+AG++ DG      ++P  + C GQ                   D  C   +F  +   
Sbjct: 2162 CHAGYVGDGLQCLEESEPPVDRCLGQ-------------PPPCHSDAMCTDLHFQEKRAG 2208

Query: 264  LIH------PTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYP 317
            + H      P  L + EA  AC   GA +A   Q+ AA + LG+  C  GWLA+GS  +P
Sbjct: 2209 VFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQ-LGFHLCLMGWLANGSTAHP 2267

Query: 318  ISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFR 351
            +  P   C      +  +G      + +  YCFR
Sbjct: 2268 VVFPVADCGNGRVGIVSLGARKNLSERWDAYCFR 2301


>gi|61743980 stabilin 2 precursor [Homo sapiens]
          Length = 2551

 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 2/94 (2%)

Query: 160  VFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPI 219
            VF     LG+Y L F +A++AC ++ A +A+++QL  A +     C+AGWL  G V YP 
Sbjct: 2199 VFHLRSPLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCSAGWLETGRVAYPT 2258

Query: 220  TKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCF 253
                + CG  + V G+ +YG        +DVFC+
Sbjct: 2259 AFASQNCG--SGVVGIVDYGPRPNKSEMWDVFCY 2290



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 29/83 (34%), Positives = 43/83 (51%), Gaps = 1/83 (1%)

Query: 269  KLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPT 328
            KLT+D+A +AC N+ A +A   Q+  A K   Y  C AGWL  G V YP +   + C   
Sbjct: 2210 KLTFDKAREACANEAATMATYNQLSYAQKAK-YHLCSAGWLETGRVAYPTAFASQNCGSG 2268

Query: 329  EAAVRFVGFPDKKHKLYGVYCFR 351
               +   G    K +++ V+C+R
Sbjct: 2269 VVGIVDYGPRPNKSEMWDVFCYR 2291


>gi|26051243 tumor necrosis factor, alpha-induced protein 6
           precursor [Homo sapiens]
          Length = 277

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 32/88 (36%), Positives = 47/88 (53%), Gaps = 2/88 (2%)

Query: 166 RLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREP 225
           R G+Y L + EA+  C  +   +A++ QL  A + G   C AGW++ G V YPI KP   
Sbjct: 43  RSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPN 102

Query: 226 CGGQNTVPGVRNYGFWDKDKSRYDVFCF 253
           CG   T  G+ +YG       R+D +C+
Sbjct: 103 CGFGKT--GIIDYGIRLNRSERWDAYCY 128



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 1/85 (1%)

Query: 269 KLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPT 328
           KLTY EA   C  +G  +A   Q+ AA KI G+  C AGW+A G V YPI +P   C   
Sbjct: 48  KLTYAEAKAVCEFEGGHLATYKQLEAARKI-GFHVCAAGWMAKGRVGYPIVKPGPNCGFG 106

Query: 329 EAAVRFVGFPDKKHKLYGVYCFRAY 353
           +  +   G    + + +  YC+  +
Sbjct: 107 KTGIIDYGIRLNRSERWDAYCYNPH 131


>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
          Length = 319

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 35/111 (31%), Positives = 56/111 (50%), Gaps = 8/111 (7%)

Query: 42  VEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYH 101
           VE  Q  + + +G +VTLPC  Y   T+   G+    I+W KL   + + V ++     +
Sbjct: 24  VETPQDVLRASQGKSVTLPCT-YHTSTSSREGL----IQWDKLLLTHTERVVIWPFSNKN 78

Query: 102 KKTYGGYQGRVFLKGGSD-SDASLVITDLTLEDYGRYKCEV--IEGLEDDT 149
                 Y+ RV +   ++ SDAS+ I  LT+ D G Y+C V  +  LE +T
Sbjct: 79  YIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNT 129


>gi|40549451 lymphatic vessel endothelial hyaluronan receptor 1
           [Homo sapiens]
          Length = 322

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 8/112 (7%)

Query: 146 EDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWC 205
           E+ ++ V+  + G+      +     LNF EA++AC      +A  DQ+  A +   + C
Sbjct: 28  EELSIQVSCRIMGITL--VSKKANQQLNFTEAKEACRLLGLSLAGKDQVETALKASFETC 85

Query: 206 NAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSR-YDVFCFTSN 256
           + GW+ DG V      P   CG      GV     W    SR +  +C+ S+
Sbjct: 86  SYGWVGDGFVVISRISPNPKCGKNGV--GVL---IWKVPVSRQFAAYCYNSS 132



 Score = 36.2 bits (82), Expect = 0.046
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 269 KLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPT 328
           +L + EA +AC   G  +A   Q+  A K   ++ C  GW+ DG V      P  +C   
Sbjct: 51  QLNFTEAKEACRLLGLSLAGKDQVETALKA-SFETCSYGWVGDGFVVISRISPNPKCGKN 109

Query: 329 EAAVRFVGFPDKKHKLYGVYCFRA 352
              V     P  +   +  YC+ +
Sbjct: 110 GVGVLIWKVPVSRQ--FAAYCYNS 131


>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
           sapiens]
          Length = 365

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 11/108 (10%)

Query: 40  LLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMG 99
           L +   +  +   +G    LPCKF   P   G     + I+W    +D  K VD  + + 
Sbjct: 20  LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGP----LDIEWLISPADNQK-VDQVIILY 74

Query: 100 YHKKTYGGY----QGRVFLKGGS--DSDASLVITDLTLEDYGRYKCEV 141
              K Y  Y    +GRV          DAS+ +T+L L D G Y+C+V
Sbjct: 75  SGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKV 122


>gi|154426280 V-set and immunoglobulin domain containing 4 isoform 2
           [Homo sapiens]
          Length = 305

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 10/100 (10%)

Query: 55  GNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFV--SMGYHKKTYGGYQGRV 112
           G+V LPC +  DP     G  ++ +KW  L       V +F+  S G H +    YQGR+
Sbjct: 35  GDVNLPCTY--DPL---QGYTQVLVKW--LVQRGSDPVTIFLRDSSGDHIQQ-AKYQGRL 86

Query: 113 FLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVV 152
            +      D SL ++ L ++D   Y CEV     D   VV
Sbjct: 87  HVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVV 126


>gi|6005958 V-set and immunoglobulin domain containing 4 isoform 1
           [Homo sapiens]
          Length = 399

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 10/100 (10%)

Query: 55  GNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFV--SMGYHKKTYGGYQGRV 112
           G+V LPC +  DP     G  ++ +KW  L       V +F+  S G H +    YQGR+
Sbjct: 35  GDVNLPCTY--DPL---QGYTQVLVKW--LVQRGSDPVTIFLRDSSGDHIQQ-AKYQGRL 86

Query: 113 FLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVV 152
            +      D SL ++ L ++D   Y CEV     D   VV
Sbjct: 87  HVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVV 126


>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
          Length = 549

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 12/106 (11%)

Query: 37  GPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFV 96
           GP ++VE     V+   G NV+L C    + T         +I W K+     + V V  
Sbjct: 58  GP-IIVEPHVTAVW---GKNVSLKCLIEVNETI-------TQISWEKIHGKSSQTVAVHH 106

Query: 97  SMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVI 142
              Y     G YQGRV  K  S +DA++ + ++   D G+Y C+ +
Sbjct: 107 PQ-YGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAV 151


>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
           sapiens]
          Length = 414

 Score = 35.4 bits (80), Expect = 0.078
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 8/102 (7%)

Query: 46  QAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYL-KEVDVFVSMGYHKKT 104
           Q  ++   G NV L C +  DP  +G   + + I+W ++ SD      +VF+S    +  
Sbjct: 29  QEVLYLAEGDNVRLGCPYVLDPEDYGP--NGLDIEWMQVNSDPAHHRENVFLSYQDKRIN 86

Query: 105 YGG---YQGRVFLKGGSDS--DASLVITDLTLEDYGRYKCEV 141
           +G     Q RV       S  DAS+ + +L + D   Y+C V
Sbjct: 87  HGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRV 128


>gi|9055238 voltage-gated sodium channel beta-3 subunit precursor
           [Homo sapiens]
          Length = 215

 Score = 33.1 bits (74), Expect = 0.39
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 1/47 (2%)

Query: 101 HKKTYGGYQGRVFLKGGSD-SDASLVITDLTLEDYGRYKCEVIEGLE 146
           H++    +QGR+   G  D  D S+ + ++TL D G Y C V    E
Sbjct: 81  HQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFE 127


>gi|93587332 voltage-gated sodium channel beta-3 subunit precursor
           [Homo sapiens]
          Length = 215

 Score = 33.1 bits (74), Expect = 0.39
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 1/47 (2%)

Query: 101 HKKTYGGYQGRVFLKGGSD-SDASLVITDLTLEDYGRYKCEVIEGLE 146
           H++    +QGR+   G  D  D S+ + ++TL D G Y C V    E
Sbjct: 81  HQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFE 127


>gi|148664224 adhesion molecule, interacts with CXADR antigen 1
           isoform 2 [Homo sapiens]
          Length = 384

 Score = 32.7 bits (73), Expect = 0.51
 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 1/65 (1%)

Query: 78  RIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGS-DSDASLVITDLTLEDYGR 136
           +I WT    ++ K+  V           G +Q RV L G    +D SL++ D+   D G 
Sbjct: 44  KIDWTLSPGEHAKDEYVLYYYSNLSVPIGRFQNRVHLMGDILCNDGSLLLQDVQEADQGT 103

Query: 137 YKCEV 141
           Y CE+
Sbjct: 104 YICEI 108


>gi|148664207 adhesion molecule, interacts with CXADR antigen 1
           isoform 1 [Homo sapiens]
          Length = 394

 Score = 32.7 bits (73), Expect = 0.51
 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 1/65 (1%)

Query: 78  RIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGS-DSDASLVITDLTLEDYGR 136
           +I WT    ++ K+  V           G +Q RV L G    +D SL++ D+   D G 
Sbjct: 54  KIDWTLSPGEHAKDEYVLYYYSNLSVPIGRFQNRVHLMGDILCNDGSLLLQDVQEADQGT 113

Query: 137 YKCEV 141
           Y CE+
Sbjct: 114 YICEI 118


>gi|63054855 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score = 32.3 bits (72), Expect = 0.66
 Identities = 17/48 (35%), Positives = 29/48 (60%), Gaps = 3/48 (6%)

Query: 108 YQGR-VFLKGGSDSDASLVITDLTLEDYGRYKCEVIEG--LEDDTVVV 152
           Y+GR V ++   +   +L I D+ LED G Y+C +  G   ++DTV++
Sbjct: 94  YKGRTVLVRDAQEGSVTLQILDVRLEDQGSYRCLIQVGNLSKEDTVIL 141


>gi|19923536 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score = 32.3 bits (72), Expect = 0.66
 Identities = 17/48 (35%), Positives = 29/48 (60%), Gaps = 3/48 (6%)

Query: 108 YQGR-VFLKGGSDSDASLVITDLTLEDYGRYKCEVIEG--LEDDTVVV 152
           Y+GR V ++   +   +L I D+ LED G Y+C +  G   ++DTV++
Sbjct: 94  YKGRTVLVRDAQEGSVTLQILDVRLEDQGSYRCLIQVGNLSKEDTVIL 141


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 32.0 bits (71), Expect = 0.86
 Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 2/50 (4%)

Query: 119   DSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGV--VFPYFPR 166
             D  A L + D+T  D G Y+C+V+    +D+    L ++GV  V+ Y+ R
Sbjct: 31621 DGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCR 31670



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 13/31 (41%), Positives = 20/31 (64%)

Query: 119  DSDASLVITDLTLEDYGRYKCEVIEGLEDDT 149
            +S+A L ITD+ +ED G Y CE +  +  D+
Sbjct: 3790 NSEAILDITDVKVEDSGSYSCEAVNDVGSDS 3820



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 28/126 (22%), Positives = 52/126 (41%), Gaps = 28/126 (22%)

Query: 32   IQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKE 91
            +  +  P  + + E +KV + +G ++ L CK         SG  +I++ W      +  +
Sbjct: 6358 LSVKEPPKFVKKLEASKV-AKQGESIQLECKI--------SGSPEIKVSW------FRND 6402

Query: 92   VDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTVV 151
             ++  S  Y+                 +S A L I + + ED G Y CE   G+ D +  
Sbjct: 6403 SELHESWKYNMSFI-------------NSVALLTINEASAEDSGDYICEAHNGVGDASCS 6449

Query: 152  VALDLQ 157
             AL ++
Sbjct: 6450 TALTVK 6455


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 32.0 bits (71), Expect = 0.86
 Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 2/50 (4%)

Query: 119   DSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGV--VFPYFPR 166
             D  A L + D+T  D G Y+C+V+    +D+    L ++GV  V+ Y+ R
Sbjct: 25316 DGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCR 25365


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 32.0 bits (71), Expect = 0.86
 Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 2/50 (4%)

Query: 119   DSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGV--VFPYFPR 166
             D  A L + D+T  D G Y+C+V+    +D+    L ++GV  V+ Y+ R
Sbjct: 25249 DGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCR 25298


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.141    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,298,214
Number of Sequences: 37866
Number of extensions: 633011
Number of successful extensions: 1668
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 1399
Number of HSP's gapped (non-prelim): 231
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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