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Search of human proteins with 4502813
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
(459 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 942 0.0
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 877 0.0
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 702 0.0
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 454 e-128
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 139 7e-33
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 139 7e-33
gi|23510413 sorting nexin 26 [Homo sapiens] 136 3e-32
gi|156119615 myosin IXA [Homo sapiens] 135 6e-32
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 135 8e-32
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 134 2e-31
gi|188497642 ARHGAP15 [Homo sapiens] 132 7e-31
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 129 4e-30
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 129 4e-30
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 129 4e-30
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 128 9e-30
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 128 9e-30
gi|91208437 GEM interacting protein [Homo sapiens] 128 1e-29
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 127 3e-29
gi|229094128 active breakpoint cluster region-related protein i... 126 4e-29
gi|38679957 active breakpoint cluster region-related protein is... 126 4e-29
gi|38679954 active breakpoint cluster region-related protein is... 126 4e-29
gi|208022687 GTPase regulator associated with the focal adhesion... 126 4e-29
gi|7662208 GTPase regulator associated with the focal adhesion k... 126 4e-29
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 126 5e-29
gi|186910302 Rac GTPase activating protein 1 [Homo sapiens] 125 8e-29
gi|186910300 Rac GTPase activating protein 1 [Homo sapiens] 125 8e-29
gi|21361397 Rac GTPase activating protein 1 [Homo sapiens] 125 8e-29
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 125 8e-29
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 123 4e-28
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 123 4e-28
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 942 bits (2435), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD 60
MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD
Sbjct: 1 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD 60
Query: 61 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG 120
QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG
Sbjct: 61 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG 120
Query: 121 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS 180
LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS
Sbjct: 121 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS 180
Query: 181 EKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCG 240
EKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCG
Sbjct: 181 EKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCG 240
Query: 241 LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE 300
LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE
Sbjct: 241 LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE 300
Query: 301 GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY 360
GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY
Sbjct: 301 GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY 360
Query: 361 PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI 420
PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI
Sbjct: 361 PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI 420
Query: 421 VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
Sbjct: 421 VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 877 bits (2266), Expect = 0.0
Identities = 433/459 (94%), Positives = 433/459 (94%), Gaps = 26/459 (5%)
Query: 1 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD 60
MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD
Sbjct: 1 MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAAD 60
Query: 61 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG 120
QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG
Sbjct: 61 QLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDG 120
Query: 121 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS 180
LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS
Sbjct: 121 LITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVS 180
Query: 181 EKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCG 240
EKR VHTFRGPHWCEYCANFMWGLIAQGVKCADCG
Sbjct: 181 EKR--------------------------VHTFRGPHWCEYCANFMWGLIAQGVKCADCG 214
Query: 241 LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE 300
LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE
Sbjct: 215 LNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSE 274
Query: 301 GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY 360
GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY
Sbjct: 275 GLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAY 334
Query: 361 PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI 420
PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI
Sbjct: 335 PKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGI 394
Query: 421 VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
Sbjct: 395 VFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 702 bits (1812), Expect = 0.0
Identities = 333/453 (73%), Positives = 390/453 (86%), Gaps = 1/453 (0%)
Query: 7 DTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVA 66
D +EY+PP+WKSYLYQLQQEAP P+RI C EVENRPKYYGREFHG+ISRE AD+LL
Sbjct: 17 DAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGV 76
Query: 67 EGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYI 126
EG+Y++RESQRQPG YTLALRFG+QT N+RL++DGKHFVGEKRFESIHDLVTDGLITLYI
Sbjct: 77 EGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYI 136
Query: 127 ETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTS 186
ETKAAEYI+KMT NPIYEH+GY TL RE ++ + K + + T ++ + ++++S
Sbjct: 137 ETKAAEYISKMTTNPIYEHIGYATLLREKVSRR-LSRSKNEPRKTNVTHEEHTAVEKISS 195
Query: 187 LVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQ 246
LVRRA L N+ YEK HNFKVHTFRGPHWCEYCANFMWGLIAQGV+C+DCGLNVHKQ
Sbjct: 196 LVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQ 255
Query: 247 CSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVS 306
CSK VPNDC+PDLK +KKVY CDLTTLVKAH T+RPMVVD+CIREIE+RGL SEGLYRVS
Sbjct: 256 CSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVS 315
Query: 307 GFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIES 366
GF++ IEDVKMAFDRDGEKADIS N+Y DINIITGALKLYFRDLPIP+ITYD Y KFI++
Sbjct: 316 GFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 375
Query: 367 AKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTL 426
AKI + DE+LE +HE L LLPPAH ETLRYLM HLK+VT++EK+N MNAENLGIVFGPTL
Sbjct: 376 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 435
Query: 427 MRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
MR PE + L+D+RYQ+L+V++LI+NED+LF
Sbjct: 436 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 454 bits (1169), Expect = e-128
Identities = 212/277 (76%), Positives = 245/277 (88%)
Query: 183 RLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLN 242
+++SLVRRA L N+ YEK HNFKVHTFRGPHWCEYCANFMWGLIAQGV+C+DCGLN
Sbjct: 56 QISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLN 115
Query: 243 VHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGL 302
VHKQCSK VPNDC+PDLK +KKVY CDLTTLVKAH T+RPMVVD+CIREIE+RGL SEGL
Sbjct: 116 VHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGL 175
Query: 303 YRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPK 362
YRVSGF++ IEDVKMAFDRDGEKADIS N+Y DINIITGALKLYFRDLPIP+ITYD Y K
Sbjct: 176 YRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSK 235
Query: 363 FIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVF 422
FI++AKI + DE+LE +HE L LLPPAH ETLRYLM HLK+VT++EK+N MNAENLGIVF
Sbjct: 236 FIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVF 295
Query: 423 GPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
GPTLMR PE + L+D+RYQ+L+V++LI+NED+LF
Sbjct: 296 GPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 139 bits (349), Expect = 7e-33
Identities = 71/190 (37%), Positives = 119/190 (62%), Gaps = 2/190 (1%)
Query: 264 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDG 323
+V+ C L L + ++ P V CIR +E+RGL+ +GLYR+SG I+ ++ D D
Sbjct: 325 QVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD- 383
Query: 324 EKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
E+ D+ +ED+++ITGALKL+FR+LP PL + + +FI + K+ D + + + +
Sbjct: 384 ERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLV 443
Query: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRY 443
+ LP + +TLR L HL RV H ++N M+ +++ IVFGPTL+R PE++ + + +
Sbjct: 444 RSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLR-PEVEETSMPMTMVF 502
Query: 444 QRLVVELLIK 453
Q VVEL+++
Sbjct: 503 QNQVVELILQ 512
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 139 bits (349), Expect = 7e-33
Identities = 71/190 (37%), Positives = 119/190 (62%), Gaps = 2/190 (1%)
Query: 264 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDG 323
+V+ C L L + ++ P V CIR +E+RGL+ +GLYR+SG I+ ++ D D
Sbjct: 352 QVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD- 410
Query: 324 EKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
E+ D+ +ED+++ITGALKL+FR+LP PL + + +FI + K+ D + + + +
Sbjct: 411 ERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLV 470
Query: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRY 443
+ LP + +TLR L HL RV H ++N M+ +++ IVFGPTL+R PE++ + + +
Sbjct: 471 RSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLR-PEVEETSMPMTMVF 529
Query: 444 QRLVVELLIK 453
Q VVEL+++
Sbjct: 530 QNQVVELILQ 539
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 136 bits (343), Expect = 3e-32
Identities = 74/202 (36%), Positives = 116/202 (57%), Gaps = 6/202 (2%)
Query: 263 KKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRD 322
++V+ CDL + P V+ C IE+ G+ +G+YR+SG S I+ ++ FD +
Sbjct: 310 QRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGV-VDGIYRLSGVSSNIQRLRHEFDSE 368
Query: 323 GEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEA 382
+DI+ ++ KLYFR+LP PL+TY Y KF E+ + +E+L +H+
Sbjct: 369 RIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDV 428
Query: 383 LKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAM-----AA 437
++ LPP H TL YL+ HL R+ H M+A NL IV+ P L+RS EL+++ AA
Sbjct: 429 IQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAA 488
Query: 438 LNDIRYQRLVVELLIKNEDILF 459
++R Q +VVE L+ + D+LF
Sbjct: 489 FREVRVQSVVVEFLLTHVDVLF 510
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 135 bits (341), Expect = 6e-32
Identities = 82/268 (30%), Positives = 139/268 (51%), Gaps = 10/268 (3%)
Query: 189 RRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCS 248
R+ K+ + + H FK + P +CEYC++ +W ++ + C C HK+C
Sbjct: 1983 RKKRRKKETDLVEEHNGHIFKATQYSIPTYCEYCSSLIW-IMDRASVCKLCKYACHKKCC 2041
Query: 249 KMVPNDC--KPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVS 306
C K D + + + +L+ L T P+VV+ I IE GL +EG+YR S
Sbjct: 2042 LKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTV-PLVVEKLINYIEMHGLYTEGIYRKS 2100
Query: 307 GFSDLIEDVKMAFDRDGEKADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIE 365
G ++ I++++ D D E SVN+ + +I++I K + RDLP PL+T++ Y +F+
Sbjct: 2101 GSTNKIKELRQGLDTDAE----SVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLR 2156
Query: 366 SAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPT 425
+ + + E + ++ + L H TL L+ HL R+ L E N M+A L IVF P
Sbjct: 2157 AMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPC 2216
Query: 426 LMRSPE-LDAMAALNDIRYQRLVVELLI 452
++R P+ D + ++ DI VEL++
Sbjct: 2217 ILRCPDTTDPLQSVQDISKTTTCVELIV 2244
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 135 bits (340), Expect = 8e-32
Identities = 72/178 (40%), Positives = 111/178 (62%), Gaps = 3/178 (1%)
Query: 284 VVDMCIREIESRGLNSEGLYRVSGFSDLIEDV-KMAFD-RDGEKADISVNMYEDINIITG 341
++ CI +E+RG+N +GLYRV G S ++ + M D + + D+ + ++ IT
Sbjct: 398 IIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITS 457
Query: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 401
ALK Y R LP PL+TY+ + FI AK P+ ++ +H + LP + E L L+ HL
Sbjct: 458 ALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHL 517
Query: 402 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
V+ H K+NLM NLG+VFGPTLMR P+ + +AAL D+++Q +VVE+LI+N + +F
Sbjct: 518 TNVSNHSKQNLMTVANLGVVFGPTLMR-PQEETVAALMDLKFQNIVVEILIENHEKIF 574
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 134 bits (336), Expect = 2e-31
Identities = 73/185 (39%), Positives = 110/185 (59%), Gaps = 1/185 (0%)
Query: 276 AHTTKR-PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYE 334
AHT + P++VD+C + +E RGL G+YRV G + I ++ ++ DI + +
Sbjct: 1155 AHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWR 1214
Query: 335 DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETL 394
D+N+I+ LK +FR LP PL T D Y FIE+ + DP ++L+TL + LP H ETL
Sbjct: 1215 DLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETL 1274
Query: 395 RYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKN 454
++L AHLK V + ++N M NL IVFGPTL+R+ E + + + Q +VE LI++
Sbjct: 1275 KFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQH 1334
Query: 455 EDILF 459
D F
Sbjct: 1335 HDWFF 1339
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 132 bits (332), Expect = 7e-31
Identities = 64/196 (32%), Positives = 119/196 (60%), Gaps = 2/196 (1%)
Query: 264 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDG 323
+++ L + + + P V CI +E RGL+ +G+YRVSG I+ ++ +++
Sbjct: 277 QIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQE- 335
Query: 324 EKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
EK ++ + +EDI+++TGALK++FR+LP PL Y + +F+E+ K D + ++E + +
Sbjct: 336 EKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLV 395
Query: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRY 443
+ LPP + +T++ L HL ++ +NLM+ ++LGIVFGPTL+R+ A++ + Y
Sbjct: 396 QKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMV-Y 454
Query: 444 QRLVVELLIKNEDILF 459
Q + EL++ +F
Sbjct: 455 QNQIAELMLSEYSKIF 470
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 129 bits (325), Expect = 4e-30
Identities = 71/208 (34%), Positives = 118/208 (56%), Gaps = 1/208 (0%)
Query: 253 NDCKPDLKHVKKVYSCDLTTLVKAHTTKR-PMVVDMCIREIESRGLNSEGLYRVSGFSDL 311
N K + K + + L A +R P++V C R +E+RGL S G+YRV G + +
Sbjct: 796 NIIKKNKKAAPRAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAV 855
Query: 312 IEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMD 371
+ ++ +R ++ ++D+N+I+ LK +FR LP PL T D Y FIE+ +I D
Sbjct: 856 VSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIED 915
Query: 372 PDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPE 431
E++ TL + ++ LP + ETL++L+ HLK + H ++N M NL +VFGPTL+R+ E
Sbjct: 916 ARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSE 975
Query: 432 LDAMAALNDIRYQRLVVELLIKNEDILF 459
+ + + + +VE LI++ D F
Sbjct: 976 DNMTDMVTHMPDRYKIVETLIQHSDWFF 1003
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 129 bits (325), Expect = 4e-30
Identities = 73/176 (41%), Positives = 100/176 (56%), Gaps = 3/176 (1%)
Query: 265 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 324
V+ + + K +K P +V C+ EIE RG+ G+YRVSG + I+ +K AFD + +
Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1066
Query: 325 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
D+SV M E D+N I G LKLYFR+LP PL T + YP F E + DP + + L
Sbjct: 1067 --DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLL 1124
Query: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALN 439
LP A+ T +L+ HLKRV E N M+ NL VFGPTL+R E ++ N
Sbjct: 1125 LSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPAN 1180
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 129 bits (325), Expect = 4e-30
Identities = 73/176 (41%), Positives = 100/176 (56%), Gaps = 3/176 (1%)
Query: 265 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 324
V+ + + K +K P +V C+ EIE RG+ G+YRVSG + I+ +K AFD + +
Sbjct: 1051 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1110
Query: 325 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
D+SV M E D+N I G LKLYFR+LP PL T + YP F E + DP + + L
Sbjct: 1111 --DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLL 1168
Query: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALN 439
LP A+ T +L+ HLKRV E N M+ NL VFGPTL+R E ++ N
Sbjct: 1169 LSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPAN 1224
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
Length = 1502
Score = 128 bits (322), Expect = 9e-30
Identities = 71/178 (39%), Positives = 104/178 (58%), Gaps = 3/178 (1%)
Query: 282 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 341
P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S+ + +N + G
Sbjct: 1275 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1332
Query: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 401
ALK +F DLP PLI Y +P+ +E+AKI D E+L L E +K P + + RY++ HL
Sbjct: 1333 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1392
Query: 402 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
RV+ K NLM A+NL I F PTLMR P+ + L+ + + VVE I+ F
Sbjct: 1393 NRVSQQHKINLMTADNLSICFWPTLMR-PDFENREFLSTTKIHQSVVETFIQQCQFFF 1449
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
Length = 1501
Score = 128 bits (322), Expect = 9e-30
Identities = 71/178 (39%), Positives = 104/178 (58%), Gaps = 3/178 (1%)
Query: 282 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 341
P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S+ + +N + G
Sbjct: 1274 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1331
Query: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 401
ALK +F DLP PLI Y +P+ +E+AKI D E+L L E +K P + + RY++ HL
Sbjct: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391
Query: 402 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
RV+ K NLM A+NL I F PTLMR P+ + L+ + + VVE I+ F
Sbjct: 1392 NRVSQQHKINLMTADNLSICFWPTLMR-PDFENREFLSTTKIHQSVVETFIQQCQFFF 1448
>gi|91208437 GEM interacting protein [Homo sapiens]
Length = 970
Score = 128 bits (321), Expect = 1e-29
Identities = 100/310 (32%), Positives = 147/310 (47%), Gaps = 35/310 (11%)
Query: 169 DERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWG 228
+ERD DG+ E L S + TL Q + ++ RGP C C FM
Sbjct: 464 EERDPDLGDGL-ENGLGSPFGKWTLSSAAQTHQLRRL--------RGPAKCRECEAFM-- 512
Query: 229 LIAQGVKCADCGLNVHKQCSKMVPNDC-KPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDM 287
G +C +C L HK+C + + C L ++ D L + + P VV
Sbjct: 513 --VSGTECEECFLTCHKRCLETLLILCGHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTK 570
Query: 288 CIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYF 347
C EIE R L+ +G+YRVSG +E + AF+ ++S N D++ + LK +
Sbjct: 571 CTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDVSSV---LKRFL 627
Query: 348 RDLPIPLITYDAYPKFIESAKIMDPD------------EQLETLHEALKLLPPAHCETLR 395
++L P+I + Y FI AK + D E + +L L LP ++ TLR
Sbjct: 628 QELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLR 687
Query: 396 YLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAA------LNDIRYQRLVVE 449
+L+AHL RV EN M+A NLGIVFGPTL+R P+ A+ L D +Q +VE
Sbjct: 688 HLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVE 747
Query: 450 LLIKNEDILF 459
LI + + +F
Sbjct: 748 FLIVHYEQIF 757
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 127 bits (318), Expect = 3e-29
Identities = 65/196 (33%), Positives = 122/196 (62%), Gaps = 3/196 (1%)
Query: 264 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDG 323
+V+ +L L + P V +CI +E GL+ +G+YRVSG +I+ ++ A + D
Sbjct: 652 QVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD- 710
Query: 324 EKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
EK D++ + +EDI++ITGALK++FR+LP PL T++ + F+ + K +P +++ + + +
Sbjct: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769
Query: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRY 443
+ LP + +T++ L HL+RV + ++N M +++ IVFGPTL++ + A++ + Y
Sbjct: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTV-Y 828
Query: 444 QRLVVELLIKNEDILF 459
Q +VEL++ +F
Sbjct: 829 QNQIVELILLELSSIF 844
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 126 bits (317), Expect = 4e-29
Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%)
Query: 265 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 324
V+ ++ + K +K P +V C+ E+E RG+ G+YR+SG + I+ +K FD + +
Sbjct: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657
Query: 325 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
DI + + + DIN I G LKLYFR+LP PL+T YP F+E + DP + + L
Sbjct: 658 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 715
Query: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 438
+ LP + T +L+ HLKRV E N M+ NL VFGPTL+R E+++ A L
Sbjct: 716 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 770
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 126 bits (317), Expect = 4e-29
Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%)
Query: 265 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 324
V+ ++ + K +K P +V C+ E+E RG+ G+YR+SG + I+ +K FD + +
Sbjct: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 703
Query: 325 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
DI + + + DIN I G LKLYFR+LP PL+T YP F+E + DP + + L
Sbjct: 704 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 761
Query: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 438
+ LP + T +L+ HLKRV E N M+ NL VFGPTL+R E+++ A L
Sbjct: 762 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 816
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 126 bits (317), Expect = 4e-29
Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%)
Query: 265 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 324
V+ ++ + K +K P +V C+ E+E RG+ G+YR+SG + I+ +K FD + +
Sbjct: 607 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 666
Query: 325 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
DI + + + DIN I G LKLYFR+LP PL+T YP F+E + DP + + L
Sbjct: 667 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 724
Query: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 438
+ LP + T +L+ HLKRV E N M+ NL VFGPTL+R E+++ A L
Sbjct: 725 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 779
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 126 bits (317), Expect = 4e-29
Identities = 63/178 (35%), Positives = 108/178 (60%), Gaps = 3/178 (1%)
Query: 284 VVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAF--DRDGEKADISVNMYEDINIITG 341
++ CI +E+RG+N +GLYR+ G + ++ + + + + + +I IT
Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITS 451
Query: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 401
ALK Y R LP PL+ Y FI++AK+ + + ++ +H + LP + + L+ LM HL
Sbjct: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
Query: 402 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
V + K+NLM NLG+VFGPTL+R P+ + +AA+ DI++Q +V+E+LI+N + +F
Sbjct: 512 ANVANNHKQNLMTVANLGVVFGPTLLR-PQEETVAAIMDIKFQNIVIEILIENHEKIF 568
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 126 bits (317), Expect = 4e-29
Identities = 63/178 (35%), Positives = 108/178 (60%), Gaps = 3/178 (1%)
Query: 284 VVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAF--DRDGEKADISVNMYEDINIITG 341
++ CI +E+RG+N +GLYR+ G + ++ + + + + + +I IT
Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITS 451
Query: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 401
ALK Y R LP PL+ Y FI++AK+ + + ++ +H + LP + + L+ LM HL
Sbjct: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
Query: 402 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
V + K+NLM NLG+VFGPTL+R P+ + +AA+ DI++Q +V+E+LI+N + +F
Sbjct: 512 ANVANNHKQNLMTVANLGVVFGPTLLR-PQEETVAAIMDIKFQNIVIEILIENHEKIF 568
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 126 bits (316), Expect = 5e-29
Identities = 71/194 (36%), Positives = 113/194 (58%), Gaps = 4/194 (2%)
Query: 266 YSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEK 325
+ LTT+V P+ ++ CI IE+ GL++EG+YRVSG +E ++ FD+D
Sbjct: 1247 FGVPLTTVVTPEKPI-PIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD-HN 1304
Query: 326 ADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKL 385
D++ + +N + GA+K +F +LP PL+ Y+ +E+ KI D +++L L E LK
Sbjct: 1305 LDLAEKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKK 1363
Query: 386 LPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQR 445
P + E +Y+++HL +V+ + K NLM +ENL I F PTLMR P+ M AL R +
Sbjct: 1364 FPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATRTYQ 1422
Query: 446 LVVELLIKNEDILF 459
++EL I+ F
Sbjct: 1423 TIIELFIQQCPFFF 1436
>gi|186910302 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 125 bits (314), Expect = 8e-29
Identities = 85/253 (33%), Positives = 129/253 (50%), Gaps = 9/253 (3%)
Query: 204 KIHNFKVHTFRGPHWCEYCAN-FMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHV 262
++H+F T P C C +G ++ +KC DC + H +C P C P L
Sbjct: 285 RLHDFVSKTVIKPESCVPCGKRIKFGKLS--LKCRDCRVVSHPECRDRCPLPCIPTLIGT 342
Query: 263 K-KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR 321
K+ L V + P +V C+ EIE RGL GLYR+SG ++++K F R
Sbjct: 343 PVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLR 402
Query: 322 DGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHE 381
K ++ +DI+ I LK + R+L PL+T+ F+E+A+I D D + +++
Sbjct: 403 --VKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQ 460
Query: 382 ALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRS--PELDAMAALN 439
A+ LP A+ +TL +LM HL+RV M+ NL VFGPT++ P D + L
Sbjct: 461 AVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQ 519
Query: 440 DIRYQRLVVELLI 452
DI+ Q VVE L+
Sbjct: 520 DIKRQPKVVERLL 532
>gi|186910300 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 125 bits (314), Expect = 8e-29
Identities = 85/253 (33%), Positives = 129/253 (50%), Gaps = 9/253 (3%)
Query: 204 KIHNFKVHTFRGPHWCEYCAN-FMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHV 262
++H+F T P C C +G ++ +KC DC + H +C P C P L
Sbjct: 285 RLHDFVSKTVIKPESCVPCGKRIKFGKLS--LKCRDCRVVSHPECRDRCPLPCIPTLIGT 342
Query: 263 K-KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR 321
K+ L V + P +V C+ EIE RGL GLYR+SG ++++K F R
Sbjct: 343 PVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLR 402
Query: 322 DGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHE 381
K ++ +DI+ I LK + R+L PL+T+ F+E+A+I D D + +++
Sbjct: 403 --VKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQ 460
Query: 382 ALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRS--PELDAMAALN 439
A+ LP A+ +TL +LM HL+RV M+ NL VFGPT++ P D + L
Sbjct: 461 AVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQ 519
Query: 440 DIRYQRLVVELLI 452
DI+ Q VVE L+
Sbjct: 520 DIKRQPKVVERLL 532
>gi|21361397 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 125 bits (314), Expect = 8e-29
Identities = 85/253 (33%), Positives = 129/253 (50%), Gaps = 9/253 (3%)
Query: 204 KIHNFKVHTFRGPHWCEYCAN-FMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHV 262
++H+F T P C C +G ++ +KC DC + H +C P C P L
Sbjct: 285 RLHDFVSKTVIKPESCVPCGKRIKFGKLS--LKCRDCRVVSHPECRDRCPLPCIPTLIGT 342
Query: 263 K-KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR 321
K+ L V + P +V C+ EIE RGL GLYR+SG ++++K F R
Sbjct: 343 PVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLR 402
Query: 322 DGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHE 381
K ++ +DI+ I LK + R+L PL+T+ F+E+A+I D D + +++
Sbjct: 403 --VKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQ 460
Query: 382 ALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRS--PELDAMAALN 439
A+ LP A+ +TL +LM HL+RV M+ NL VFGPT++ P D + L
Sbjct: 461 AVGELPQANRDTLAFLMIHLQRVA-QSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQ 519
Query: 440 DIRYQRLVVELLI 452
DI+ Q VVE L+
Sbjct: 520 DIKRQPKVVERLL 532
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 125 bits (314), Expect = 8e-29
Identities = 69/206 (33%), Positives = 116/206 (56%), Gaps = 8/206 (3%)
Query: 260 KHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAF 319
K + CDLT +++ P V+ C IE+ G+ +G+YR+SG + I+ ++ F
Sbjct: 13 KGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGI-VDGIYRLSGVTSNIQRLRQEF 71
Query: 320 DRDGEKADISVNMY-EDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLET 378
D + D++ +Y +DI+ + KLYFR+LP PL+TY+ Y KF E+ + QL
Sbjct: 72 GSD-QCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLAR 130
Query: 379 LHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAM--- 435
+ ++ LPP+H TL YL+ HL + + M+A NL +V+ P L+RS E++A
Sbjct: 131 IQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCN 190
Query: 436 --AALNDIRYQRLVVELLIKNEDILF 459
AA +R Q++V+E ++ + D +F
Sbjct: 191 GDAAFLAVRVQQVVIEFILNHVDQIF 216
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 123 bits (308), Expect = 4e-28
Identities = 79/271 (29%), Positives = 139/271 (51%), Gaps = 16/271 (5%)
Query: 194 KENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPN 253
++ E+ + H F + P CE C +++W L+ + + C+ C + HK+C + +
Sbjct: 1621 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIW-LMDKALLCSVCKMTCHKKCVHKIQS 1679
Query: 254 DC--------KPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRV 305
C +P ++ D T KA P+V++ + +E GL +EGLYR
Sbjct: 1680 HCSYTYGRKGEPGVEPGHFGVCVDSLTSDKASV---PIVLEKLLEHVEMHGLYTEGLYRK 1736
Query: 306 SGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIE 365
SG ++ +++ A D A + + + I+ ITG LK + R+LP PL+T+ Y F+
Sbjct: 1737 SGAANRTRELRQALQTD--PAAVKLENFP-IHAITGVLKQWLRELPEPLMTFAQYGDFLR 1793
Query: 366 SAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPT 425
+ ++ + EQL ++ L+ LP A+ +L L+ HL +V L E N M+ L I+F P
Sbjct: 1794 AVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPC 1853
Query: 426 LMRSPE-LDAMAALNDIRYQRLVVELLIKNE 455
L+R P+ D + ++ D+ VE+LIK +
Sbjct: 1854 LLRCPDNSDPLTSMKDVLKITTCVEMLIKEQ 1884
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 123 bits (308), Expect = 4e-28
Identities = 79/271 (29%), Positives = 139/271 (51%), Gaps = 16/271 (5%)
Query: 194 KENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPN 253
++ E+ + H F + P CE C +++W L+ + + C+ C + HK+C + +
Sbjct: 1621 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIW-LMDKALLCSVCKMTCHKKCVHKIQS 1679
Query: 254 DC--------KPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRV 305
C +P ++ D T KA P+V++ + +E GL +EGLYR
Sbjct: 1680 HCSYTYGRKGEPGVEPGHFGVCVDSLTSDKASV---PIVLEKLLEHVEMHGLYTEGLYRK 1736
Query: 306 SGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIE 365
SG ++ +++ A D A + + + I+ ITG LK + R+LP PL+T+ Y F+
Sbjct: 1737 SGAANRTRELRQALQTD--PAAVKLENFP-IHAITGVLKQWLRELPEPLMTFAQYGDFLR 1793
Query: 366 SAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPT 425
+ ++ + EQL ++ L+ LP A+ +L L+ HL +V L E N M+ L I+F P
Sbjct: 1794 AVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPC 1853
Query: 426 LMRSPE-LDAMAALNDIRYQRLVVELLIKNE 455
L+R P+ D + ++ D+ VE+LIK +
Sbjct: 1854 LLRCPDNSDPLTSMKDVLKITTCVEMLIKEQ 1884
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,422,191
Number of Sequences: 37866
Number of extensions: 772116
Number of successful extensions: 2954
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 109
Number of HSP's that attempted gapping in prelim test: 2502
Number of HSP's gapped (non-prelim): 399
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.