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Search of human proteins with 4502483
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502483 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 7 isoform 1 [Homo sapiens]
(373 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502483 Ras association (RalGDS/AF-6) domain family (N-termin... 743 0.0
gi|221136876 Ras association (RalGDS/AF-6) domain family (N-term... 629 e-180
gi|221136872 Ras association (RalGDS/AF-6) domain family (N-term... 627 e-180
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi... 182 4e-46
gi|56549696 E1A binding protein p400 [Homo sapiens] 47 2e-05
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens] 47 3e-05
gi|4504063 golgin 97 [Homo sapiens] 47 4e-05
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 46 5e-05
gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isofo... 45 8e-05
gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isofor... 45 8e-05
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 45 8e-05
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 45 8e-05
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 45 8e-05
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 43 5e-04
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 43 5e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 43 5e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 43 5e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 43 5e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 43 5e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 43 5e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 43 5e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 43 5e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 43 5e-04
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 43 5e-04
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 43 5e-04
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 43 5e-04
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 42 7e-04
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 42 7e-04
gi|21735548 centrosomal protein 2 [Homo sapiens] 42 9e-04
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 42 9e-04
>gi|4502483 Ras association (RalGDS/AF-6) domain family (N-terminal)
member 7 isoform 1 [Homo sapiens]
Length = 373
Score = 743 bits (1917), Expect = 0.0
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL 60
MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL
Sbjct: 1 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL 60
Query: 61 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL 120
LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL
Sbjct: 61 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL 120
Query: 121 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 180
GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR
Sbjct: 121 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 180
Query: 181 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER 240
REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER
Sbjct: 181 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER 240
Query: 241 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG 300
LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG
Sbjct: 241 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG 300
Query: 301 AALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPA 360
AALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPA
Sbjct: 301 AALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPA 360
Query: 361 PEWCPLAAQPQAL 373
PEWCPLAAQPQAL
Sbjct: 361 PEWCPLAAQPQAL 373
>gi|221136876 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 7 isoform 3 [Homo sapiens]
Length = 320
Score = 629 bits (1621), Expect = e-180
Identities = 318/319 (99%), Positives = 318/319 (99%)
Query: 1 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL 60
MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL
Sbjct: 1 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL 60
Query: 61 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL 120
LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL
Sbjct: 61 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL 120
Query: 121 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 180
GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR
Sbjct: 121 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 180
Query: 181 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER 240
REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER
Sbjct: 181 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER 240
Query: 241 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG 300
LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG
Sbjct: 241 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG 300
Query: 301 AALPPPPRPDRGPPGTQGP 319
AALPPPPRPDRGPPGTQ P
Sbjct: 301 AALPPPPRPDRGPPGTQWP 319
>gi|221136872 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 7 isoform 2 [Homo sapiens]
Length = 337
Score = 627 bits (1616), Expect = e-180
Identities = 317/317 (100%), Positives = 317/317 (100%)
Query: 1 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL 60
MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL
Sbjct: 1 MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQL 60
Query: 61 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL 120
LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL
Sbjct: 61 LPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAAL 120
Query: 121 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 180
GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR
Sbjct: 121 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 180
Query: 181 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER 240
REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER
Sbjct: 181 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATER 240
Query: 241 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG 300
LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG
Sbjct: 241 LHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG 300
Query: 301 AALPPPPRPDRGPPGTQ 317
AALPPPPRPDRGPPGTQ
Sbjct: 301 AALPPPPRPDRGPPGTQ 317
>gi|23503243 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 8 [Homo sapiens]
Length = 392
Score = 182 bits (462), Expect = 4e-46
Identities = 138/372 (37%), Positives = 190/372 (51%), Gaps = 77/372 (20%)
Query: 8 MELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPV 67
MELKVWVDG+QR+VCGV+E TTCQEVVIALAQAIG+TGR+ L+++ R+ ER L P E P+
Sbjct: 1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPI 60
Query: 68 GAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPP-PERCLIRASLPVKPRAALGCEPRK 126
+ GQ+ASDVQ +LRRTGPSL+ RP+SDS PER L R SLP P A L + K
Sbjct: 61 ISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLP--PLAKLRPQIDK 118
Query: 127 TL-TPEP-APSLSRPGPAAPVTPTPG--------------CCT--------------DLR 156
++ EP SL+ G A + G C T L+
Sbjct: 119 SIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQ 178
Query: 157 GLELRVQRNAEELGHEAFWEQ--------------------------------ELRREQA 184
+E +++ N E+ FWEQ EL+ EQ
Sbjct: 179 SIEKQLESNEIEI---RFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQE 235
Query: 185 REREGQARLQALSAATAEHAARLQALDAQARALEAELQL------AAEAPGPPSPMASAT 238
E++ + +LQ + E +L+ AQ R +E+ L+ EA +
Sbjct: 236 NEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKI 295
Query: 239 ERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQ 298
++ ++ +Q +QS ++ + V R+L A + LQ + QELE+L +ELRQ NLQQFIQQ
Sbjct: 296 GKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQ 355
Query: 299 TG---AALPPPP 307
TG LP P
Sbjct: 356 TGTKVTVLPAEP 367
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 47.4 bits (111), Expect = 2e-05
Identities = 29/98 (29%), Positives = 40/98 (40%), Gaps = 8/98 (8%)
Query: 273 LQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDRGPPGTQGPLPPAREESLLGAP 332
+Q + E + +E + QQ QQ A PPPP+P PP Q P P + ++ P
Sbjct: 2475 IQVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQP 2534
Query: 333 SESHAGAQPRPRGGPHDAELLEVAAAPAPEWCPLAAQP 370
QP+P+ P P P P AQP
Sbjct: 2535 PAGPPAVQPQPQPQPQ--------TQPQPVQAPAKAQP 2564
Score = 38.5 bits (88), Expect = 0.010
Identities = 57/244 (23%), Positives = 81/244 (33%), Gaps = 31/244 (12%)
Query: 134 PSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARL 193
PS P AAP T + LRG +A A + + A Q
Sbjct: 1444 PSTHPPRTAAPTTASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPAS 1503
Query: 194 QALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSA 253
+ +AA+ H A+L+A + A PG P P A A+ +R
Sbjct: 1504 ASSTAASPAHPAKLRA----------QTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVL 1553
Query: 254 EVQGSLALVS-RALEAAERA-----------------LQAQAQELEELNRELRQCNLQQF 295
Q L S ++ A+ A LQ Q + + +LRQ Q
Sbjct: 1554 PSQAQARLPSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQP 1613
Query: 296 IQQTGAALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEV 355
+Q G+ L P G P + P P + G++P P GGP A L
Sbjct: 1614 LQLQGSVLQIVSAP--GQPYLRAPGPVVMQTVSQAGAVHGALGSKP-PAGGPSPAPLTPQ 1670
Query: 356 AAAP 359
P
Sbjct: 1671 VGVP 1674
>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
Length = 775
Score = 47.0 bits (110), Expect = 3e-05
Identities = 38/148 (25%), Positives = 71/148 (47%), Gaps = 9/148 (6%)
Query: 153 TDLRGLELRVQRNAEELGHEAFWEQELR------REQARE-REGQARLQALSAATAEHAA 205
T + LELR++ E L A+ +++ ++ RE E ++ LQA+ +
Sbjct: 259 TQRQDLELRLEETREALAGRAYAAEQMEGFELQTKQLTREVEELKSELQAIRDEKNQPDP 318
Query: 206 RLQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRA 265
RLQ L +A L++ Q A+ A A ++L Q V+E++ A ++ ++ VS
Sbjct: 319 RLQELQEEAARLKSHFQ--AQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSEL 376
Query: 266 LEAAERALQAQAQELEELNRELRQCNLQ 293
L E+A Q +++L + Q +L+
Sbjct: 377 LGTYEKAKQKDQLAIQKLKERILQLDLE 404
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 46.6 bits (109), Expect = 4e-05
Identities = 43/142 (30%), Positives = 70/142 (49%), Gaps = 6/142 (4%)
Query: 158 LELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARAL 217
LE R+++N L E ++ L+ + E+ + Q L AA + A + L+ + R L
Sbjct: 303 LEKRLEQN---LSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVREL 359
Query: 218 EAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQG-SLALVSRALEAAERALQAQ 276
E LQ + E + +A E Q+LA ++S+ VQ +LAL + LE + AL+AQ
Sbjct: 360 EQTLQASEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLERTQ-ALEAQ 418
Query: 277 AQELEELNRELRQCNLQQFIQQ 298
LE R Q +Q ++Q
Sbjct: 419 IVALER-TRAADQTTAEQGMRQ 439
Score = 28.9 bits (63), Expect = 7.8
Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 11/130 (8%)
Query: 158 LELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARAL 217
LE+ ++++ ++ F EQ + R + + AL+ E + ++ L+ + L
Sbjct: 91 LEIALEKH-QDSSMRKFQEQNETFQANRAKMAEGLALALARKDQEWSEKMDQLEKEKNIL 149
Query: 218 EAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQA 277
A+LQ M + + L Q + Q L+ + L E +L
Sbjct: 150 TAQLQ----------EMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLKKEESLGKME 199
Query: 278 QELEELNREL 287
QELE REL
Sbjct: 200 QELEARTREL 209
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 46.2 bits (108), Expect = 5e-05
Identities = 68/265 (25%), Positives = 99/265 (37%), Gaps = 37/265 (13%)
Query: 89 PSLAGRPSSDSCPPPERCLIRASLPVKPRAALGCEPRKTLTPEPAPSLSRPGPAAPVTPT 148
P++A P+S P P A +P P P + S + T
Sbjct: 427 PAMAPAPAS--APAPASAPAPAPVPT---------PAMVSAPSSTVNASASVKTSAGTTD 475
Query: 149 PGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQ 208
P T L + R+ R E EQE Q RE Q + + E + RL+
Sbjct: 476 PEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLE 535
Query: 209 ALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAE-VQGSLALVSRALE 267
A QAR E +LQ AE + A++ER+ AE Q +R E
Sbjct: 536 A--EQAREKEEQLQRQAE-----------------ERALREREEAERAQRQKEEEARVRE 576
Query: 268 AAERALQAQAQ--ELEELNRELRQCNLQQFIQQT--GAALPPPPRPDRGPPGTQGPLPPA 323
AER Q + + + EE R R+ L++ +++T A R +G L
Sbjct: 577 EAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGG 636
Query: 324 REESLLGAPSESHAGAQPRPRGGPH 348
E S L P ++A +P G PH
Sbjct: 637 TEVSAL--PCTTNAPGNGKPVGSPH 659
>gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isoform b
[Homo sapiens]
Length = 1173
Score = 45.4 bits (106), Expect = 8e-05
Identities = 65/205 (31%), Positives = 80/205 (39%), Gaps = 50/205 (24%)
Query: 158 LELRVQRNAEELGHEAF----WEQELRREQAR-EREGQARLQALSAATAEHAARLQALDA 212
LE QRN E+ E + +LR EQ R ERE Q + Q L A ARLQ +
Sbjct: 850 LEQERQRNFEKQREERAALEKLQSQLRHEQQRWERERQWQHQELERA----GARLQEREG 905
Query: 213 QARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERA 272
+AR L ERL Q+ A ERQ Q L L A+RA
Sbjct: 906 EARQLR--------------------ERLEQERAELERQRQAYQHDL----ERLREAQRA 941
Query: 273 LQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDRGPPGTQGPLPPAREESLLGAP 332
++ + + LE L R +Q ALPP + PP PP+ L P
Sbjct: 942 VERERERLELLRRLKKQ-------NTAPGALPPDTLAEAQPPSH----PPSFNGEGLEGP 990
Query: 333 SESHAGAQPRPRG-GPHDAELLEVA 356
S P G GP AE EVA
Sbjct: 991 RVSML-----PSGVGPEYAERPEVA 1010
>gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isoform a
[Homo sapiens]
Length = 1015
Score = 45.4 bits (106), Expect = 8e-05
Identities = 65/205 (31%), Positives = 80/205 (39%), Gaps = 50/205 (24%)
Query: 158 LELRVQRNAEELGHEAF----WEQELRREQAR-EREGQARLQALSAATAEHAARLQALDA 212
LE QRN E+ E + +LR EQ R ERE Q + Q L A ARLQ +
Sbjct: 692 LEQERQRNFEKQREERAALEKLQSQLRHEQQRWERERQWQHQELERA----GARLQEREG 747
Query: 213 QARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERA 272
+AR L ERL Q+ A ERQ Q L L A+RA
Sbjct: 748 EARQLR--------------------ERLEQERAELERQRQAYQHDL----ERLREAQRA 783
Query: 273 LQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDRGPPGTQGPLPPAREESLLGAP 332
++ + + LE L R +Q ALPP + PP PP+ L P
Sbjct: 784 VERERERLELLRRLKKQ-------NTAPGALPPDTLAEAQPPSH----PPSFNGEGLEGP 832
Query: 333 SESHAGAQPRPRG-GPHDAELLEVA 356
S P G GP AE EVA
Sbjct: 833 RVSML-----PSGVGPEYAERPEVA 852
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 45.4 bits (106), Expect = 8e-05
Identities = 59/232 (25%), Positives = 94/232 (40%), Gaps = 35/232 (15%)
Query: 158 LELRVQRNAEELGHEAFWEQELRREQAR----EREGQARLQALSAATAEHAARLQALDAQ 213
L R +R E+ E++ RRE+ + E+E Q RL+ + A E R + +
Sbjct: 391 LHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQE 450
Query: 214 ARALEAELQ-----LAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGS---LALVSRA 265
+ + E Q L + + + S ++ Q +++Q + G L R
Sbjct: 451 YKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRG 510
Query: 266 LEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDR--GPPGTQGPLPPA 323
+ A++ A A+E+EE R +Q N + G+ P PP P GPPG PP
Sbjct: 511 MNPADKP--AWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPM 568
Query: 324 REESLLGAPSESHAGAQPRPRGGPHDAEL-----LEVAAAPAPEWCPLAAQP 370
+ P E P+ GPH + + L+ AAP P L QP
Sbjct: 569 QR------PVE--------PQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQP 606
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 45.4 bits (106), Expect = 8e-05
Identities = 59/232 (25%), Positives = 94/232 (40%), Gaps = 35/232 (15%)
Query: 158 LELRVQRNAEELGHEAFWEQELRREQAR----EREGQARLQALSAATAEHAARLQALDAQ 213
L R +R E+ E++ RRE+ + E+E Q RL+ + A E R + +
Sbjct: 391 LHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQE 450
Query: 214 ARALEAELQ-----LAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGS---LALVSRA 265
+ + E Q L + + + S ++ Q +++Q + G L R
Sbjct: 451 YKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRG 510
Query: 266 LEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDR--GPPGTQGPLPPA 323
+ A++ A A+E+EE R +Q N + G+ P PP P GPPG PP
Sbjct: 511 MNPADKP--AWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPM 568
Query: 324 REESLLGAPSESHAGAQPRPRGGPHDAEL-----LEVAAAPAPEWCPLAAQP 370
+ P E P+ GPH + + L+ AAP P L QP
Sbjct: 569 QR------PVE--------PQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQP 606
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 45.4 bits (106), Expect = 8e-05
Identities = 59/232 (25%), Positives = 94/232 (40%), Gaps = 35/232 (15%)
Query: 158 LELRVQRNAEELGHEAFWEQELRREQAR----EREGQARLQALSAATAEHAARLQALDAQ 213
L R +R E+ E++ RRE+ + E+E Q RL+ + A E R + +
Sbjct: 391 LHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQE 450
Query: 214 ARALEAELQ-----LAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGS---LALVSRA 265
+ + E Q L + + + S ++ Q +++Q + G L R
Sbjct: 451 YKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRG 510
Query: 266 LEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDR--GPPGTQGPLPPA 323
+ A++ A A+E+EE R +Q N + G+ P PP P GPPG PP
Sbjct: 511 MNPADKP--AWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPM 568
Query: 324 REESLLGAPSESHAGAQPRPRGGPHDAEL-----LEVAAAPAPEWCPLAAQP 370
+ P E P+ GPH + + L+ AAP P L QP
Sbjct: 569 QR------PVE--------PQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQP 606
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 42.7 bits (99), Expect = 5e-04
Identities = 72/263 (27%), Positives = 97/263 (36%), Gaps = 55/263 (20%)
Query: 155 LRGLEL--RVQRNAEELGHEAFWEQELRREQARER----EGQAR--------LQALSAAT 200
L+ LEL QR AE L E E+E RR Q RE EGQ R +QA
Sbjct: 361 LQELELLQEAQRQAERLLQE---EEERRRSQHRELQQALEGQLREAEQARASMQAEMELK 417
Query: 201 AEHAAR----LQALDAQARALEAELQLAAEAPGPPSPMASATERLHQD-----------L 245
E AAR ++ L+ + L+ LQL +A + A RL ++
Sbjct: 418 EEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLK 477
Query: 246 AVQERQSAEVQGSLALVSRALEAAERALQAQAQELEEL--------------NRELRQC- 290
QER Q + + + R+LQ Q+LEE+ R+LRQ
Sbjct: 478 EEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQAS 537
Query: 291 -NLQQFIQQTGAALPPPPRPDRGP------PGTQGPLPPAREESLLGAPS-ESHAGAQPR 342
N++ + Q + P D+ P G Q PL R+ SL S P
Sbjct: 538 TNVKHWNVQMNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLKRLTRWGSQGNRTPS 597
Query: 343 PRGGPHDAELLEVAAAPAPEWCP 365
P L APAP P
Sbjct: 598 PNSNEQQKSLNGGDEAPAPASTP 620
Score = 35.4 bits (80), Expect = 0.083
Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 16/133 (12%)
Query: 158 LELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARAL 217
+ +R+Q + H+ ++ RREQ +RE + AA E RLQ L +
Sbjct: 309 MAIRLQAEGKTSLHKDL--KQKRREQREQRERRR------AAKEEELLRLQQLQEEKERK 360
Query: 218 EAELQLAAEAPGPPSPMASATERLHQDLAVQER-QSAEVQGSLALVSRALEAAERALQAQ 276
EL+L EA ERL Q+ + R Q E+Q +L R E A ++QA+
Sbjct: 361 LQELELLQEA-------QRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAE 413
Query: 277 AQELEELNRELRQ 289
+ EE RQ
Sbjct: 414 MELKEEEAARQRQ 426
Score = 34.7 bits (78), Expect = 0.14
Identities = 39/143 (27%), Positives = 62/143 (43%), Gaps = 14/143 (9%)
Query: 161 RVQRNAEELGHEAFWEQELRREQAREREGQA--RLQALSAATAEHAARLQALDAQARALE 218
R QR E A E+ LR +Q +E + + L+ L A + LQ + + R+
Sbjct: 330 REQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQH 389
Query: 219 AELQLAAEAPGPPSPMASATERLHQDL----AVQERQSAE--------VQGSLALVSRAL 266
ELQ A E + A A+ + +L A ++RQ + +Q +L L +A
Sbjct: 390 RELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKAR 449
Query: 267 EAAERALQAQAQELEELNRELRQ 289
E AQ + LEE +L+Q
Sbjct: 450 RDEESVRIAQTRLLEEEEEKLKQ 472
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 42.7 bits (99), Expect = 5e-04
Identities = 56/221 (25%), Positives = 89/221 (40%), Gaps = 34/221 (15%)
Query: 158 LELRVQRNAEELGHEAFWEQELRREQAR----EREGQARLQALSAATAEHAARLQALDAQ 213
L R +R E+ E++ RRE+ + E+E Q RL+ + A E R + +
Sbjct: 391 LHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQE 450
Query: 214 ARALEAELQ-----LAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGS---LALVSRA 265
+ + E Q L + + + S ++ Q +++Q + G L R
Sbjct: 451 YKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRG 510
Query: 266 LEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDR--GPPGTQGPLPPA 323
+ A++ A A+E+EE R +Q N + G+ P PP P GPPG PP
Sbjct: 511 MNPADKP--AWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPM 568
Query: 324 REESLLGAPSESHAGAQPRPRGGPH----DAELLEVAAAPA 360
+ P E P+ GPH D +AA PA
Sbjct: 569 QR------PVE--------PQEGPHKSLQDQPTRNLAAFPA 595
Score = 31.6 bits (70), Expect = 1.2
Identities = 49/191 (25%), Positives = 70/191 (36%), Gaps = 35/191 (18%)
Query: 130 PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAE--ELGHEAFWEQELRREQARER 187
PEP + PGP P++ TP +QR E E H++ +Q R A
Sbjct: 547 PEPPIPQASPGPPGPLSQTP-----------PMQRPVEPQEGPHKSLQDQPTRNLAAFPA 595
Query: 188 EGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGP-PSPMASATERLHQDLA 246
A+ A TA +AR + +E PGP P+P A
Sbjct: 596 SHDPD-PAIPAPTATPSAR-------GAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAPPK 647
Query: 247 VQERQSAEVQGSLALVSRAL--EAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALP 304
V +R S+ ++ AL A + AQA + Q LQ+ ++ P
Sbjct: 648 VPQRTSS--------IATALNTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAER---GTP 696
Query: 305 PPPRPDRGPPG 315
PP P PPG
Sbjct: 697 KPPGPPAQPPG 707
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 42.7 bits (99), Expect = 5e-04
Identities = 78/296 (26%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 31 QEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQF-----VLR 85
+E +A Q + R V+ EK+RQL AQA + A ++Q V+R
Sbjct: 1346 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAE--REAKELQQRMQEEVVR 1403
Query: 86 RTGPSLAGRPSSDSCPPPERCLIRAS---LPVKPRAALGCEPRKTLTPEPAPSLSRPGPA 142
R ++ + S + L ++S + K R A E R L E + R
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEEEIRVVRLQLE 1462
Query: 143 APVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQARE---REGQARLQALSAA 199
A G +L+ L R + AE +A E E R Q ++ R+ QA ++ S
Sbjct: 1463 ATERQRGGAEGELQALRARAEE-AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1521
Query: 200 TAEHAA--------------RLQALDAQARALEAELQLAAEAP-GPPSPMASATERLHQD 244
AE A RLQA +A+ R +AE++ A + + SA L
Sbjct: 1522 KAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1581
Query: 245 LAVQERQSAEVQGSL----ALVSRALEAAERALQAQAQ---ELEELNRELRQCNLQ 293
A ++A+++ SL V++ E AER Q QA+ EE REL + L+
Sbjct: 1582 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1637
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 9/137 (6%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
E RVQ E E+ R +Q+ E + QAR QA +AA R +A AR +
Sbjct: 2095 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA---EKLRKEAEQEAARRAQ 2151
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQE-RQSAEVQGSLALVSRALEAAERALQAQA 277
AE +A A A H+ A Q RQ A+V+ L + LE +
Sbjct: 2152 AE-----QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLD 2206
Query: 278 QELEELNRELRQCNLQQ 294
+EL+ L E + Q+
Sbjct: 2207 EELQRLKAEATEAARQR 2223
Score = 35.8 bits (81), Expect = 0.064
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 160 LRVQRNAEELGHE---AFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARA 216
LR++ AEE+ + A E E ++E+A ERE + R +A A + Q L+ Q +
Sbjct: 1642 LRLRLQAEEVAQQKSLAQAEAEKQKEEA-EREARRRGKAEEQAVRQRELAEQELEKQRQL 1700
Query: 217 LEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQ 276
E Q A + + TE+ Q + E + A +Q A ++ + E L
Sbjct: 1701 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1760
Query: 277 AQELEEL 283
E+E L
Sbjct: 1761 RAEMEVL 1767
Score = 33.1 bits (74), Expect = 0.41
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 177 QELRREQAREREGQARLQALSAATAEHAARLQALD----AQARAL-EAELQLAAEAPGPP 231
Q +E+A + + A A + A+ AARL+ L AQ RAL E L+ +A
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 232 SPMASATERLHQDLAVQERQSAEVQGSLALVSRAL----EAAERALQAQAQELEELNREL 287
+ + + E L Q + + Q+ +Q +++ L + +R L+A+ Q E++ E
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2382
Query: 288 RQCNLQ 293
+ L+
Sbjct: 2383 ERLKLR 2388
Score = 32.3 bits (72), Expect = 0.71
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 234 MASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
++ R+ ++ + E+Q AE + LA V ALE + +A AQ + RE ++ LQ
Sbjct: 1337 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE--LQ 1394
Query: 294 QFIQQ 298
Q +Q+
Sbjct: 1395 QRMQE 1399
Score = 29.3 bits (64), Expect = 6.0
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 25/183 (13%)
Query: 118 AALGCEPRKTLT-PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEEL-----GH 171
A L E K L PEP+P+ P + + T G +R L + + G
Sbjct: 1041 ARLSAEAEKVLALPEPSPAA--PTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGT 1098
Query: 172 EAFWEQELRREQAREREGQA------RLQALSAATAEHAARLQALDAQARALEAELQLAA 225
+ E+ LR + + +E QA L+A A+ + A+ +A AL EL+ A
Sbjct: 1099 QGA-EEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQ 1157
Query: 226 EAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNR 285
E ERL Q ++ + + +A + +A + +ELE+L R
Sbjct: 1158 EVG----------ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGR 1207
Query: 286 ELR 288
+LR
Sbjct: 1208 QLR 1210
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 42.7 bits (99), Expect = 5e-04
Identities = 78/296 (26%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 31 QEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQF-----VLR 85
+E +A Q + R V+ EK+RQL AQA + A ++Q V+R
Sbjct: 1350 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAE--REAKELQQRMQEEVVR 1407
Query: 86 RTGPSLAGRPSSDSCPPPERCLIRAS---LPVKPRAALGCEPRKTLTPEPAPSLSRPGPA 142
R ++ + S + L ++S + K R A E R L E + R
Sbjct: 1408 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEEEIRVVRLQLE 1466
Query: 143 APVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQARE---REGQARLQALSAA 199
A G +L+ L R + AE +A E E R Q ++ R+ QA ++ S
Sbjct: 1467 ATERQRGGAEGELQALRARAEE-AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1525
Query: 200 TAEHAA--------------RLQALDAQARALEAELQLAAEAP-GPPSPMASATERLHQD 244
AE A RLQA +A+ R +AE++ A + + SA L
Sbjct: 1526 KAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1585
Query: 245 LAVQERQSAEVQGSL----ALVSRALEAAERALQAQAQ---ELEELNRELRQCNLQ 293
A ++A+++ SL V++ E AER Q QA+ EE REL + L+
Sbjct: 1586 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1641
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 9/137 (6%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
E RVQ E E+ R +Q+ E + QAR QA +AA R +A AR +
Sbjct: 2099 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA---EKLRKEAEQEAARRAQ 2155
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQE-RQSAEVQGSLALVSRALEAAERALQAQA 277
AE +A A A H+ A Q RQ A+V+ L + LE +
Sbjct: 2156 AE-----QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLD 2210
Query: 278 QELEELNRELRQCNLQQ 294
+EL+ L E + Q+
Sbjct: 2211 EELQRLKAEATEAARQR 2227
Score = 35.8 bits (81), Expect = 0.064
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 160 LRVQRNAEELGHE---AFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARA 216
LR++ AEE+ + A E E ++E+A ERE + R +A A + Q L+ Q +
Sbjct: 1646 LRLRLQAEEVAQQKSLAQAEAEKQKEEA-EREARRRGKAEEQAVRQRELAEQELEKQRQL 1704
Query: 217 LEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQ 276
E Q A + + TE+ Q + E + A +Q A ++ + E L
Sbjct: 1705 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1764
Query: 277 AQELEEL 283
E+E L
Sbjct: 1765 RAEMEVL 1771
Score = 33.1 bits (74), Expect = 0.41
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 177 QELRREQAREREGQARLQALSAATAEHAARLQALD----AQARAL-EAELQLAAEAPGPP 231
Q +E+A + + A A + A+ AARL+ L AQ RAL E L+ +A
Sbjct: 2267 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2326
Query: 232 SPMASATERLHQDLAVQERQSAEVQGSLALVSRAL----EAAERALQAQAQELEELNREL 287
+ + + E L Q + + Q+ +Q +++ L + +R L+A+ Q E++ E
Sbjct: 2327 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2386
Query: 288 RQCNLQ 293
+ L+
Sbjct: 2387 ERLKLR 2392
Score = 32.3 bits (72), Expect = 0.71
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 234 MASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
++ R+ ++ + E+Q AE + LA V ALE + +A AQ + RE ++ LQ
Sbjct: 1341 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE--LQ 1398
Query: 294 QFIQQ 298
Q +Q+
Sbjct: 1399 QRMQE 1403
Score = 29.3 bits (64), Expect = 6.0
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 25/183 (13%)
Query: 118 AALGCEPRKTLT-PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEEL-----GH 171
A L E K L PEP+P+ P + + T G +R L + + G
Sbjct: 1045 ARLSAEAEKVLALPEPSPAA--PTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGT 1102
Query: 172 EAFWEQELRREQAREREGQA------RLQALSAATAEHAARLQALDAQARALEAELQLAA 225
+ E+ LR + + +E QA L+A A+ + A+ +A AL EL+ A
Sbjct: 1103 QGA-EEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQ 1161
Query: 226 EAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNR 285
E ERL Q ++ + + +A + +A + +ELE+L R
Sbjct: 1162 EVG----------ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGR 1211
Query: 286 ELR 288
+LR
Sbjct: 1212 QLR 1214
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 42.7 bits (99), Expect = 5e-04
Identities = 78/296 (26%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 31 QEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQF-----VLR 85
+E +A Q + R V+ EK+RQL AQA + A ++Q V+R
Sbjct: 1346 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAE--REAKELQQRMQEEVVR 1403
Query: 86 RTGPSLAGRPSSDSCPPPERCLIRAS---LPVKPRAALGCEPRKTLTPEPAPSLSRPGPA 142
R ++ + S + L ++S + K R A E R L E + R
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEEEIRVVRLQLE 1462
Query: 143 APVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQARE---REGQARLQALSAA 199
A G +L+ L R + AE +A E E R Q ++ R+ QA ++ S
Sbjct: 1463 ATERQRGGAEGELQALRARAEE-AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1521
Query: 200 TAEHAA--------------RLQALDAQARALEAELQLAAEAP-GPPSPMASATERLHQD 244
AE A RLQA +A+ R +AE++ A + + SA L
Sbjct: 1522 KAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1581
Query: 245 LAVQERQSAEVQGSL----ALVSRALEAAERALQAQAQ---ELEELNRELRQCNLQ 293
A ++A+++ SL V++ E AER Q QA+ EE REL + L+
Sbjct: 1582 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1637
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 9/137 (6%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
E RVQ E E+ R +Q+ E + QAR QA +AA R +A AR +
Sbjct: 2095 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA---EKLRKEAEQEAARRAQ 2151
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQE-RQSAEVQGSLALVSRALEAAERALQAQA 277
AE +A A A H+ A Q RQ A+V+ L + LE +
Sbjct: 2152 AE-----QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLD 2206
Query: 278 QELEELNRELRQCNLQQ 294
+EL+ L E + Q+
Sbjct: 2207 EELQRLKAEATEAARQR 2223
Score = 35.8 bits (81), Expect = 0.064
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 160 LRVQRNAEELGHE---AFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARA 216
LR++ AEE+ + A E E ++E+A ERE + R +A A + Q L+ Q +
Sbjct: 1642 LRLRLQAEEVAQQKSLAQAEAEKQKEEA-EREARRRGKAEEQAVRQRELAEQELEKQRQL 1700
Query: 217 LEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQ 276
E Q A + + TE+ Q + E + A +Q A ++ + E L
Sbjct: 1701 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1760
Query: 277 AQELEEL 283
E+E L
Sbjct: 1761 RAEMEVL 1767
Score = 33.1 bits (74), Expect = 0.41
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 177 QELRREQAREREGQARLQALSAATAEHAARLQALD----AQARAL-EAELQLAAEAPGPP 231
Q +E+A + + A A + A+ AARL+ L AQ RAL E L+ +A
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 232 SPMASATERLHQDLAVQERQSAEVQGSLALVSRAL----EAAERALQAQAQELEELNREL 287
+ + + E L Q + + Q+ +Q +++ L + +R L+A+ Q E++ E
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2382
Query: 288 RQCNLQ 293
+ L+
Sbjct: 2383 ERLKLR 2388
Score = 32.3 bits (72), Expect = 0.71
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 234 MASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
++ R+ ++ + E+Q AE + LA V ALE + +A AQ + RE ++ LQ
Sbjct: 1337 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE--LQ 1394
Query: 294 QFIQQ 298
Q +Q+
Sbjct: 1395 QRMQE 1399
Score = 29.3 bits (64), Expect = 6.0
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 25/183 (13%)
Query: 118 AALGCEPRKTLT-PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEEL-----GH 171
A L E K L PEP+P+ P + + T G +R L + + G
Sbjct: 1041 ARLSAEAEKVLALPEPSPAA--PTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGT 1098
Query: 172 EAFWEQELRREQAREREGQA------RLQALSAATAEHAARLQALDAQARALEAELQLAA 225
+ E+ LR + + +E QA L+A A+ + A+ +A AL EL+ A
Sbjct: 1099 QGA-EEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQ 1157
Query: 226 EAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNR 285
E ERL Q ++ + + +A + +A + +ELE+L R
Sbjct: 1158 EVG----------ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGR 1207
Query: 286 ELR 288
+LR
Sbjct: 1208 QLR 1210
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 42.7 bits (99), Expect = 5e-04
Identities = 78/296 (26%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 31 QEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQF-----VLR 85
+E +A Q + R V+ EK+RQL AQA + A ++Q V+R
Sbjct: 1314 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAE--REAKELQQRMQEEVVR 1371
Query: 86 RTGPSLAGRPSSDSCPPPERCLIRAS---LPVKPRAALGCEPRKTLTPEPAPSLSRPGPA 142
R ++ + S + L ++S + K R A E R L E + R
Sbjct: 1372 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEEEIRVVRLQLE 1430
Query: 143 APVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQARE---REGQARLQALSAA 199
A G +L+ L R + AE +A E E R Q ++ R+ QA ++ S
Sbjct: 1431 ATERQRGGAEGELQALRARAEE-AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1489
Query: 200 TAEHAA--------------RLQALDAQARALEAELQLAAEAP-GPPSPMASATERLHQD 244
AE A RLQA +A+ R +AE++ A + + SA L
Sbjct: 1490 KAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1549
Query: 245 LAVQERQSAEVQGSL----ALVSRALEAAERALQAQAQ---ELEELNRELRQCNLQ 293
A ++A+++ SL V++ E AER Q QA+ EE REL + L+
Sbjct: 1550 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1605
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 9/137 (6%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
E RVQ E E+ R +Q+ E + QAR QA +AA R +A AR +
Sbjct: 2063 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA---EKLRKEAEQEAARRAQ 2119
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQE-RQSAEVQGSLALVSRALEAAERALQAQA 277
AE +A A A H+ A Q RQ A+V+ L + LE +
Sbjct: 2120 AE-----QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLD 2174
Query: 278 QELEELNRELRQCNLQQ 294
+EL+ L E + Q+
Sbjct: 2175 EELQRLKAEATEAARQR 2191
Score = 35.8 bits (81), Expect = 0.064
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 160 LRVQRNAEELGHE---AFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARA 216
LR++ AEE+ + A E E ++E+A ERE + R +A A + Q L+ Q +
Sbjct: 1610 LRLRLQAEEVAQQKSLAQAEAEKQKEEA-EREARRRGKAEEQAVRQRELAEQELEKQRQL 1668
Query: 217 LEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQ 276
E Q A + + TE+ Q + E + A +Q A ++ + E L
Sbjct: 1669 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1728
Query: 277 AQELEEL 283
E+E L
Sbjct: 1729 RAEMEVL 1735
Score = 33.1 bits (74), Expect = 0.41
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 177 QELRREQAREREGQARLQALSAATAEHAARLQALD----AQARAL-EAELQLAAEAPGPP 231
Q +E+A + + A A + A+ AARL+ L AQ RAL E L+ +A
Sbjct: 2231 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2290
Query: 232 SPMASATERLHQDLAVQERQSAEVQGSLALVSRAL----EAAERALQAQAQELEELNREL 287
+ + + E L Q + + Q+ +Q +++ L + +R L+A+ Q E++ E
Sbjct: 2291 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2350
Query: 288 RQCNLQ 293
+ L+
Sbjct: 2351 ERLKLR 2356
Score = 32.3 bits (72), Expect = 0.71
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 234 MASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
++ R+ ++ + E+Q AE + LA V ALE + +A AQ + RE ++ LQ
Sbjct: 1305 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE--LQ 1362
Query: 294 QFIQQ 298
Q +Q+
Sbjct: 1363 QRMQE 1367
Score = 29.3 bits (64), Expect = 6.0
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 25/183 (13%)
Query: 118 AALGCEPRKTLT-PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEEL-----GH 171
A L E K L PEP+P+ P + + T G +R L + + G
Sbjct: 1009 ARLSAEAEKVLALPEPSPAA--PTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGT 1066
Query: 172 EAFWEQELRREQAREREGQA------RLQALSAATAEHAARLQALDAQARALEAELQLAA 225
+ E+ LR + + +E QA L+A A+ + A+ +A AL EL+ A
Sbjct: 1067 QGA-EEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQ 1125
Query: 226 EAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNR 285
E ERL Q ++ + + +A + +A + +ELE+L R
Sbjct: 1126 EVG----------ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGR 1175
Query: 286 ELR 288
+LR
Sbjct: 1176 QLR 1178
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 42.7 bits (99), Expect = 5e-04
Identities = 78/296 (26%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 31 QEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQF-----VLR 85
+E +A Q + R V+ EK+RQL AQA + A ++Q V+R
Sbjct: 1483 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAE--REAKELQQRMQEEVVR 1540
Query: 86 RTGPSLAGRPSSDSCPPPERCLIRAS---LPVKPRAALGCEPRKTLTPEPAPSLSRPGPA 142
R ++ + S + L ++S + K R A E R L E + R
Sbjct: 1541 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEEEIRVVRLQLE 1599
Query: 143 APVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQARE---REGQARLQALSAA 199
A G +L+ L R + AE +A E E R Q ++ R+ QA ++ S
Sbjct: 1600 ATERQRGGAEGELQALRARAEE-AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1658
Query: 200 TAEHAA--------------RLQALDAQARALEAELQLAAEAP-GPPSPMASATERLHQD 244
AE A RLQA +A+ R +AE++ A + + SA L
Sbjct: 1659 KAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1718
Query: 245 LAVQERQSAEVQGSL----ALVSRALEAAERALQAQAQ---ELEELNRELRQCNLQ 293
A ++A+++ SL V++ E AER Q QA+ EE REL + L+
Sbjct: 1719 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1774
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 9/137 (6%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
E RVQ E E+ R +Q+ E + QAR QA +AA R +A AR +
Sbjct: 2232 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA---EKLRKEAEQEAARRAQ 2288
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQE-RQSAEVQGSLALVSRALEAAERALQAQA 277
AE +A A A H+ A Q RQ A+V+ L + LE +
Sbjct: 2289 AE-----QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLD 2343
Query: 278 QELEELNRELRQCNLQQ 294
+EL+ L E + Q+
Sbjct: 2344 EELQRLKAEATEAARQR 2360
Score = 35.8 bits (81), Expect = 0.064
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 160 LRVQRNAEELGHE---AFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARA 216
LR++ AEE+ + A E E ++E+A ERE + R +A A + Q L+ Q +
Sbjct: 1779 LRLRLQAEEVAQQKSLAQAEAEKQKEEA-EREARRRGKAEEQAVRQRELAEQELEKQRQL 1837
Query: 217 LEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQ 276
E Q A + + TE+ Q + E + A +Q A ++ + E L
Sbjct: 1838 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1897
Query: 277 AQELEEL 283
E+E L
Sbjct: 1898 RAEMEVL 1904
Score = 33.1 bits (74), Expect = 0.41
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 177 QELRREQAREREGQARLQALSAATAEHAARLQALD----AQARAL-EAELQLAAEAPGPP 231
Q +E+A + + A A + A+ AARL+ L AQ RAL E L+ +A
Sbjct: 2400 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2459
Query: 232 SPMASATERLHQDLAVQERQSAEVQGSLALVSRAL----EAAERALQAQAQELEELNREL 287
+ + + E L Q + + Q+ +Q +++ L + +R L+A+ Q E++ E
Sbjct: 2460 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2519
Query: 288 RQCNLQ 293
+ L+
Sbjct: 2520 ERLKLR 2525
Score = 32.3 bits (72), Expect = 0.71
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 234 MASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
++ R+ ++ + E+Q AE + LA V ALE + +A AQ + RE ++ LQ
Sbjct: 1474 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE--LQ 1531
Query: 294 QFIQQ 298
Q +Q+
Sbjct: 1532 QRMQE 1536
Score = 29.3 bits (64), Expect = 6.0
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 25/183 (13%)
Query: 118 AALGCEPRKTLT-PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEEL-----GH 171
A L E K L PEP+P+ P + + T G +R L + + G
Sbjct: 1178 ARLSAEAEKVLALPEPSPAA--PTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGT 1235
Query: 172 EAFWEQELRREQAREREGQA------RLQALSAATAEHAARLQALDAQARALEAELQLAA 225
+ E+ LR + + +E QA L+A A+ + A+ +A AL EL+ A
Sbjct: 1236 QGA-EEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQ 1294
Query: 226 EAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNR 285
E ERL Q ++ + + +A + +A + +ELE+L R
Sbjct: 1295 EVG----------ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGR 1344
Query: 286 ELR 288
+LR
Sbjct: 1345 QLR 1347
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 42.7 bits (99), Expect = 5e-04
Identities = 78/296 (26%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 31 QEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQF-----VLR 85
+E +A Q + R V+ EK+RQL AQA + A ++Q V+R
Sbjct: 1324 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAE--REAKELQQRMQEEVVR 1381
Query: 86 RTGPSLAGRPSSDSCPPPERCLIRAS---LPVKPRAALGCEPRKTLTPEPAPSLSRPGPA 142
R ++ + S + L ++S + K R A E R L E + R
Sbjct: 1382 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEEEIRVVRLQLE 1440
Query: 143 APVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQARE---REGQARLQALSAA 199
A G +L+ L R + AE +A E E R Q ++ R+ QA ++ S
Sbjct: 1441 ATERQRGGAEGELQALRARAEE-AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1499
Query: 200 TAEHAA--------------RLQALDAQARALEAELQLAAEAP-GPPSPMASATERLHQD 244
AE A RLQA +A+ R +AE++ A + + SA L
Sbjct: 1500 KAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1559
Query: 245 LAVQERQSAEVQGSL----ALVSRALEAAERALQAQAQ---ELEELNRELRQCNLQ 293
A ++A+++ SL V++ E AER Q QA+ EE REL + L+
Sbjct: 1560 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1615
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 9/137 (6%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
E RVQ E E+ R +Q+ E + QAR QA +AA R +A AR +
Sbjct: 2073 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA---EKLRKEAEQEAARRAQ 2129
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQE-RQSAEVQGSLALVSRALEAAERALQAQA 277
AE +A A A H+ A Q RQ A+V+ L + LE +
Sbjct: 2130 AE-----QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLD 2184
Query: 278 QELEELNRELRQCNLQQ 294
+EL+ L E + Q+
Sbjct: 2185 EELQRLKAEATEAARQR 2201
Score = 35.8 bits (81), Expect = 0.064
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 160 LRVQRNAEELGHE---AFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARA 216
LR++ AEE+ + A E E ++E+A ERE + R +A A + Q L+ Q +
Sbjct: 1620 LRLRLQAEEVAQQKSLAQAEAEKQKEEA-EREARRRGKAEEQAVRQRELAEQELEKQRQL 1678
Query: 217 LEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQ 276
E Q A + + TE+ Q + E + A +Q A ++ + E L
Sbjct: 1679 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1738
Query: 277 AQELEEL 283
E+E L
Sbjct: 1739 RAEMEVL 1745
Score = 33.1 bits (74), Expect = 0.41
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 177 QELRREQAREREGQARLQALSAATAEHAARLQALD----AQARAL-EAELQLAAEAPGPP 231
Q +E+A + + A A + A+ AARL+ L AQ RAL E L+ +A
Sbjct: 2241 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2300
Query: 232 SPMASATERLHQDLAVQERQSAEVQGSLALVSRAL----EAAERALQAQAQELEELNREL 287
+ + + E L Q + + Q+ +Q +++ L + +R L+A+ Q E++ E
Sbjct: 2301 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2360
Query: 288 RQCNLQ 293
+ L+
Sbjct: 2361 ERLKLR 2366
Score = 32.3 bits (72), Expect = 0.71
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 234 MASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
++ R+ ++ + E+Q AE + LA V ALE + +A AQ + RE ++ LQ
Sbjct: 1315 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE--LQ 1372
Query: 294 QFIQQ 298
Q +Q+
Sbjct: 1373 QRMQE 1377
Score = 29.3 bits (64), Expect = 6.0
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 25/183 (13%)
Query: 118 AALGCEPRKTLT-PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEEL-----GH 171
A L E K L PEP+P+ P + + T G +R L + + G
Sbjct: 1019 ARLSAEAEKVLALPEPSPAA--PTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGT 1076
Query: 172 EAFWEQELRREQAREREGQA------RLQALSAATAEHAARLQALDAQARALEAELQLAA 225
+ E+ LR + + +E QA L+A A+ + A+ +A AL EL+ A
Sbjct: 1077 QGA-EEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQ 1135
Query: 226 EAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNR 285
E ERL Q ++ + + +A + +A + +ELE+L R
Sbjct: 1136 EVG----------ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGR 1185
Query: 286 ELR 288
+LR
Sbjct: 1186 QLR 1188
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 42.7 bits (99), Expect = 5e-04
Identities = 78/296 (26%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 31 QEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQF-----VLR 85
+E +A Q + R V+ EK+RQL AQA + A ++Q V+R
Sbjct: 1332 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAE--REAKELQQRMQEEVVR 1389
Query: 86 RTGPSLAGRPSSDSCPPPERCLIRAS---LPVKPRAALGCEPRKTLTPEPAPSLSRPGPA 142
R ++ + S + L ++S + K R A E R L E + R
Sbjct: 1390 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEEEIRVVRLQLE 1448
Query: 143 APVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQARE---REGQARLQALSAA 199
A G +L+ L R + AE +A E E R Q ++ R+ QA ++ S
Sbjct: 1449 ATERQRGGAEGELQALRARAEE-AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1507
Query: 200 TAEHAA--------------RLQALDAQARALEAELQLAAEAP-GPPSPMASATERLHQD 244
AE A RLQA +A+ R +AE++ A + + SA L
Sbjct: 1508 KAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1567
Query: 245 LAVQERQSAEVQGSL----ALVSRALEAAERALQAQAQ---ELEELNRELRQCNLQ 293
A ++A+++ SL V++ E AER Q QA+ EE REL + L+
Sbjct: 1568 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1623
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 9/137 (6%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
E RVQ E E+ R +Q+ E + QAR QA +AA R +A AR +
Sbjct: 2081 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA---EKLRKEAEQEAARRAQ 2137
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQE-RQSAEVQGSLALVSRALEAAERALQAQA 277
AE +A A A H+ A Q RQ A+V+ L + LE +
Sbjct: 2138 AE-----QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLD 2192
Query: 278 QELEELNRELRQCNLQQ 294
+EL+ L E + Q+
Sbjct: 2193 EELQRLKAEATEAARQR 2209
Score = 35.8 bits (81), Expect = 0.064
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 160 LRVQRNAEELGHE---AFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARA 216
LR++ AEE+ + A E E ++E+A ERE + R +A A + Q L+ Q +
Sbjct: 1628 LRLRLQAEEVAQQKSLAQAEAEKQKEEA-EREARRRGKAEEQAVRQRELAEQELEKQRQL 1686
Query: 217 LEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQ 276
E Q A + + TE+ Q + E + A +Q A ++ + E L
Sbjct: 1687 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1746
Query: 277 AQELEEL 283
E+E L
Sbjct: 1747 RAEMEVL 1753
Score = 33.1 bits (74), Expect = 0.41
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 177 QELRREQAREREGQARLQALSAATAEHAARLQALD----AQARAL-EAELQLAAEAPGPP 231
Q +E+A + + A A + A+ AARL+ L AQ RAL E L+ +A
Sbjct: 2249 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2308
Query: 232 SPMASATERLHQDLAVQERQSAEVQGSLALVSRAL----EAAERALQAQAQELEELNREL 287
+ + + E L Q + + Q+ +Q +++ L + +R L+A+ Q E++ E
Sbjct: 2309 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2368
Query: 288 RQCNLQ 293
+ L+
Sbjct: 2369 ERLKLR 2374
Score = 32.3 bits (72), Expect = 0.71
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 234 MASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
++ R+ ++ + E+Q AE + LA V ALE + +A AQ + RE ++ LQ
Sbjct: 1323 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE--LQ 1380
Query: 294 QFIQQ 298
Q +Q+
Sbjct: 1381 QRMQE 1385
Score = 29.3 bits (64), Expect = 6.0
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 25/183 (13%)
Query: 118 AALGCEPRKTLT-PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEEL-----GH 171
A L E K L PEP+P+ P + + T G +R L + + G
Sbjct: 1027 ARLSAEAEKVLALPEPSPAA--PTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGT 1084
Query: 172 EAFWEQELRREQAREREGQA------RLQALSAATAEHAARLQALDAQARALEAELQLAA 225
+ E+ LR + + +E QA L+A A+ + A+ +A AL EL+ A
Sbjct: 1085 QGA-EEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQ 1143
Query: 226 EAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNR 285
E ERL Q ++ + + +A + +A + +ELE+L R
Sbjct: 1144 EVG----------ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGR 1193
Query: 286 ELR 288
+LR
Sbjct: 1194 QLR 1196
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 42.7 bits (99), Expect = 5e-04
Identities = 78/296 (26%), Positives = 121/296 (40%), Gaps = 37/296 (12%)
Query: 31 QEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQF-----VLR 85
+E +A Q + R V+ EK+RQL AQA + A ++Q V+R
Sbjct: 1373 EEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAE--REAKELQQRMQEEVVR 1430
Query: 86 RTGPSLAGRPSSDSCPPPERCLIRAS---LPVKPRAALGCEPRKTLTPEPAPSLSRPGPA 142
R ++ + S + L ++S + K R A E R L E + R
Sbjct: 1431 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAE-RSRLRIEEEIRVVRLQLE 1489
Query: 143 APVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQARE---REGQARLQALSAA 199
A G +L+ L R + AE +A E E R Q ++ R+ QA ++ S
Sbjct: 1490 ATERQRGGAEGELQALRARAEE-AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1548
Query: 200 TAEHAA--------------RLQALDAQARALEAELQLAAEAP-GPPSPMASATERLHQD 244
AE A RLQA +A+ R +AE++ A + + SA L
Sbjct: 1549 KAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1608
Query: 245 LAVQERQSAEVQGSL----ALVSRALEAAERALQAQAQ---ELEELNRELRQCNLQ 293
A ++A+++ SL V++ E AER Q QA+ EE REL + L+
Sbjct: 1609 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1664
Score = 40.4 bits (93), Expect = 0.003
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 9/137 (6%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
E RVQ E E+ R +Q+ E + QAR QA +AA R +A AR +
Sbjct: 2122 EARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA---EKLRKEAEQEAARRAQ 2178
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQE-RQSAEVQGSLALVSRALEAAERALQAQA 277
AE +A A A H+ A Q RQ A+V+ L + LE +
Sbjct: 2179 AE-----QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLD 2233
Query: 278 QELEELNRELRQCNLQQ 294
+EL+ L E + Q+
Sbjct: 2234 EELQRLKAEATEAARQR 2250
Score = 35.8 bits (81), Expect = 0.064
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 160 LRVQRNAEELGHE---AFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARA 216
LR++ AEE+ + A E E ++E+A ERE + R +A A + Q L+ Q +
Sbjct: 1669 LRLRLQAEEVAQQKSLAQAEAEKQKEEA-EREARRRGKAEEQAVRQRELAEQELEKQRQL 1727
Query: 217 LEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQ 276
E Q A + + TE+ Q + E + A +Q A ++ + E L
Sbjct: 1728 AEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV 1787
Query: 277 AQELEEL 283
E+E L
Sbjct: 1788 RAEMEVL 1794
Score = 33.1 bits (74), Expect = 0.41
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 177 QELRREQAREREGQARLQALSAATAEHAARLQALD----AQARAL-EAELQLAAEAPGPP 231
Q +E+A + + A A + A+ AARL+ L AQ RAL E L+ +A
Sbjct: 2290 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2349
Query: 232 SPMASATERLHQDLAVQERQSAEVQGSLALVSRAL----EAAERALQAQAQELEELNREL 287
+ + + E L Q + + Q+ +Q +++ L + +R L+A+ Q E++ E
Sbjct: 2350 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2409
Query: 288 RQCNLQ 293
+ L+
Sbjct: 2410 ERLKLR 2415
Score = 32.3 bits (72), Expect = 0.71
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 234 MASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
++ R+ ++ + E+Q AE + LA V ALE + +A AQ + RE ++ LQ
Sbjct: 1364 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE--LQ 1421
Query: 294 QFIQQ 298
Q +Q+
Sbjct: 1422 QRMQE 1426
Score = 29.3 bits (64), Expect = 6.0
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 25/183 (13%)
Query: 118 AALGCEPRKTLT-PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEEL-----GH 171
A L E K L PEP+P+ P + + T G +R L + + G
Sbjct: 1068 ARLSAEAEKVLALPEPSPAA--PTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGT 1125
Query: 172 EAFWEQELRREQAREREGQA------RLQALSAATAEHAARLQALDAQARALEAELQLAA 225
+ E+ LR + + +E QA L+A A+ + A+ +A AL EL+ A
Sbjct: 1126 QGA-EEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQ 1184
Query: 226 EAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNR 285
E ERL Q ++ + + +A + +A + +ELE+L R
Sbjct: 1185 EVG----------ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGR 1234
Query: 286 ELR 288
+LR
Sbjct: 1235 QLR 1237
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 42.7 bits (99), Expect = 5e-04
Identities = 57/223 (25%), Positives = 85/223 (38%), Gaps = 34/223 (15%)
Query: 121 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 180
G E + PE + G + + PG T LR LR+Q+ +E +Q L+
Sbjct: 325 GSEEEEEEVPE------QEGEPSSIVNVPGEST-LRRDFLRLQQENKERSEALRRQQLLQ 377
Query: 181 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATE- 239
+Q RE+E R AE R++ Q R LE + + EA E
Sbjct: 378 EQQLREQEEYKR-----QLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQ 432
Query: 240 ---RLHQDLAVQERQSAE---VQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
R ++L + ++ E + V R E R L+ + + LE L ++L Q
Sbjct: 433 EEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAM 492
Query: 294 ----------QFIQQTGAALPPPPRPDRGPPGTQGPLPPAREE 326
Q QQ PPPP+ +R P P P A E
Sbjct: 493 LLHDHRRPHPQHSQQ-----PPPPQQERSKPSFHAPEPKAHYE 530
Score = 32.3 bits (72), Expect = 0.71
Identities = 46/191 (24%), Positives = 66/191 (34%), Gaps = 34/191 (17%)
Query: 156 RGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQAR 215
R E +R EEL E+E RR + +R + + + E L+ L Q
Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487
Query: 216 ALEAELQLAAEAPGPP---SPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERA 272
+A L P P P ER E ++ E A+RA
Sbjct: 488 QEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAH------------YEPADRA 535
Query: 273 LQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDRGPPGTQGPLPPAREESLLGAP 332
+E+E+ R+ + + +QTG L PP P+R ES
Sbjct: 536 -----REVEDRFRKTNHSSPEAQSKQTGRVLEPP--------------VPSRSESFSNGN 576
Query: 333 SESHAGAQPRP 343
SES A RP
Sbjct: 577 SESVHPALQRP 587
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 42.7 bits (99), Expect = 5e-04
Identities = 57/223 (25%), Positives = 85/223 (38%), Gaps = 34/223 (15%)
Query: 121 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 180
G E + PE + G + + PG T LR LR+Q+ +E +Q L+
Sbjct: 325 GSEEEEEEVPE------QEGEPSSIVNVPGEST-LRRDFLRLQQENKERSEALRRQQLLQ 377
Query: 181 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATE- 239
+Q RE+E R AE R++ Q R LE + + EA E
Sbjct: 378 EQQLREQEEYKR-----QLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQ 432
Query: 240 ---RLHQDLAVQERQSAE---VQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
R ++L + ++ E + V R E R L+ + + LE L ++L Q
Sbjct: 433 EEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAM 492
Query: 294 ----------QFIQQTGAALPPPPRPDRGPPGTQGPLPPAREE 326
Q QQ PPPP+ +R P P P A E
Sbjct: 493 LLHDHRRPHPQHSQQ-----PPPPQQERSKPSFHAPEPKAHYE 530
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 42.7 bits (99), Expect = 5e-04
Identities = 84/366 (22%), Positives = 130/366 (35%), Gaps = 46/366 (12%)
Query: 25 SEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQFVL 84
+E+T E A+A+ V VQ +E L+ E P Q + + V+ +
Sbjct: 297 TEETPDAEAATAVAE------NSVKVQPPPAEEAPLV--EFPAEIQPPSAEESPSVELLA 348
Query: 85 RRTGPSLAGRPSSDS----CPPPERCLIRASLPVKPRAALGCEPRKTLTPEPAPSLSRPG 140
PS PS + PPP L + R+ + + P PA
Sbjct: 349 EILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEA 408
Query: 141 PAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQ--ALSA 198
PA PT V+ ++ + +E RE+ARE + ++ A A
Sbjct: 409 PAKVEPPT-------------VEETLADV--QPLLPEEAPREEARELQLSTAMETPAEEA 453
Query: 199 ATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGS 258
T + + A+ + E +L A E P +P A A L ++ + +E AEVQ
Sbjct: 454 PTEFQSPLPKETTAEEASAEIQLLAATEPPADETP-AEARSPLSEETSAEEAH-AEVQSP 511
Query: 259 LALVSRALEAA--------------ERALQAQAQELEELNRELRQCNLQQFIQQTGAALP 304
LA + A EA+ E +AQ+ EE + E +Q G ++
Sbjct: 512 LAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS-PSAKGVSIE 570
Query: 305 PPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPAPEWC 364
P + P G + A L A +E+ A P P E P E
Sbjct: 571 EAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEA 630
Query: 365 PLAAQP 370
P QP
Sbjct: 631 PAEVQP 636
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 42.4 bits (98), Expect = 7e-04
Identities = 63/249 (25%), Positives = 93/249 (37%), Gaps = 55/249 (22%)
Query: 121 GCEPRKTLTPEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELR 180
G E + PE + G + + PG T LR LR+Q+ +E +Q L+
Sbjct: 325 GSEEEEEEVPE------QEGEPSSIVNVPGEST-LRRDFLRLQQENKERSEALRRQQLLQ 377
Query: 181 REQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATE- 239
+Q RE+E R AE R++ Q R LE + + EA E
Sbjct: 378 EQQLREQEEYKR-----QLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQ 432
Query: 240 ---RLHQDLA-----VQERQSAE-----VQGSLALVSRALEAAERALQAQAQELEELNRE 286
R ++L +ER+ AE V+ + R LE +R L+ Q+L +
Sbjct: 433 EEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAM 492
Query: 287 LRQCN------------LQQFIQQTGAAL-----------------PPPPRPDRGPPGTQ 317
L +C LQ+ +QQ A L PPPP+ +R P
Sbjct: 493 LLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFH 552
Query: 318 GPLPPAREE 326
P P A E
Sbjct: 553 APEPKAHYE 561
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 42.4 bits (98), Expect = 7e-04
Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 5/132 (3%)
Query: 158 LELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARAL 217
L+ ++Q +LG QEL + R +E +RLQA + Q L + L
Sbjct: 997 LQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSVLEIQG---QELHRKLEVL 1053
Query: 218 EAELQLAAEAPGPPSPMASATERLHQDLA-VQERQSAEVQGSLALVSRALEAAERALQAQ 276
E E++ A ++ A R H+ LA +Q RQ AE++G L + R L+A RAL+
Sbjct: 1054 EEEVRAARQSQEETRGQQQALLRDHKALAQLQRRQEAELEG-LLVRHRDLKANMRALELA 1112
Query: 277 AQELEELNRELR 288
+EL+ + +L+
Sbjct: 1113 HRELQGRHEQLQ 1124
Score = 40.8 bits (94), Expect = 0.002
Identities = 58/229 (25%), Positives = 91/229 (39%), Gaps = 38/229 (16%)
Query: 156 RGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQAR 215
RGLE ++R E EL RE+ + + L+ A A+L+ Q R
Sbjct: 1152 RGLEEELRRLQSEHDRAQMLLAELSRERGELQGERGELRGRLARLELERAQLEMQSQQLR 1211
Query: 216 ALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQS----AEVQG----SLALVSRALE 267
+L L+A + + E L Q + QE ++ AEVQ + L+ R+LE
Sbjct: 1212 ESNQQLDLSA------CRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLE 1265
Query: 268 AAERALQAQAQELEELN--RELRQCNLQQFIQQTGAALPPP------------------- 306
+ + + Q + L++LN R +Q +++ + Q P P
Sbjct: 1266 SRDHLHREQREYLDQLNALRREKQKLVEKIMDQYRVLEPVPLPRTKKGSWLADKVKRLMR 1325
Query: 307 PRPDRGPPG--TQGPLPPAREESLLGAP-SESHAGAQPRPRGGPHDAEL 352
PR + GPPG G ESL G P +E G + G P A +
Sbjct: 1326 PRREGGPPGGLRLGADGAGSTESLGGPPETELPEGREADGTGSPSPAPM 1374
Score = 38.9 bits (89), Expect = 0.008
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)
Query: 163 QRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQAL----DAQARALE 218
Q+ +E WE + E G A +AL A+ + +AL +AQAR LE
Sbjct: 699 QQKSEGALEVQVWEGPIPGESLAS--GVAEQEALREEVAQLRRKAEALGDELEAQARKLE 756
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQ 278
A+ AA + A H++ Q + A ++ ++ + LE+A + +A +
Sbjct: 757 AQNTEAARLSKELAQARRAEAEAHREAEAQAWEQARLREAVEAAGQELESASQEREALVE 816
Query: 279 ELEELNRELRQ 289
L RE RQ
Sbjct: 817 ALAAAGRERRQ 827
Score = 36.2 bits (82), Expect = 0.049
Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 7/123 (5%)
Query: 175 WEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPM 234
WE+E R +A+ + R+Q L + +H + + AL+AEL+ A +
Sbjct: 828 WEREGSRLRAQSEAAEERMQVLESEGRQHLEEAERERREKEALQAELEKAVVR---GKEL 884
Query: 235 ASATERLHQDL--AVQERQS--AEVQGSLALVSRALEAAERALQAQAQELEELNRELRQC 290
+ E L ++L A ERQ E + + E LQA A EE EL+
Sbjct: 885 GARLEHLQRELEQAALERQEFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTR 944
Query: 291 NLQ 293
LQ
Sbjct: 945 ALQ 947
Score = 33.1 bits (74), Expect = 0.41
Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 4/126 (3%)
Query: 177 QELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE---AELQLAAEAPGPPSP 233
QEL + + QA +Q L A QAL QA+ E E + E G
Sbjct: 272 QELEEKAELLLDSQAEVQGLEAEIRRLRQEAQALSGQAKRAELYREEAEALRERAGRLPR 331
Query: 234 MASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQ 293
+ R + L E ++++ L S LEA++ L+ Q + E L + +
Sbjct: 332 LQEELRRCRERLQAAEAYKSQLEEERVL-SGVLEASKALLEEQLEAARERCARLHETQRE 390
Query: 294 QFIQQT 299
+ +T
Sbjct: 391 NLLLRT 396
Score = 32.3 bits (72), Expect = 0.71
Identities = 48/217 (22%), Positives = 75/217 (34%), Gaps = 28/217 (12%)
Query: 154 DLRGLELRVQRNAEELGHEAFWEQELRR--EQAREREGQARLQALSAATAEH-----AAR 206
+L L +V + AEE E EL+R E G+A L + + + A R
Sbjct: 404 ELDSLRHQVDQLAEE---NVELELELQRSLEPPPGSPGEAPLAGAAPSLQDEVREAEAGR 460
Query: 207 LQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEV---QGSLALVS 263
L+ L+ + R L LQ+ PG P+ A ++E V LV
Sbjct: 461 LRTLERENRELRGLLQVLQGQPGGQHPLLEAPREDPVLPVLEEAPQTPVAFDHSPQGLVQ 520
Query: 264 RALEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPRPDRGPPGTQGPLPPA 323
+A + +AL L+ + +C P PD P + PL A
Sbjct: 521 KARDGGPQALDLAPPALDSVLEASAEC---------------PQAPDSDPQEAESPLQAA 565
Query: 324 REESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPA 360
+ S +G+ + P A +PA
Sbjct: 566 AMDPQASDWSPQESGSPVETQESPEKAGRRSSLQSPA 602
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 42.0 bits (97), Expect = 9e-04
Identities = 57/202 (28%), Positives = 80/202 (39%), Gaps = 8/202 (3%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
E R Q +E ++ ++ R R++E +A Q A + + DA ALE
Sbjct: 1789 EAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALE 1848
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQERQ---SAEVQGSLALVSRALEAAERALQ- 274
E G RL ++LAV+ R+ EV G L SR E A ALQ
Sbjct: 1849 QAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQ 1908
Query: 275 ---AQAQELEELNRELRQCNLQ-QFIQQTGAALPPPPRPDRGPPGTQGPLPPAREESLLG 330
QAQE E R L+ LQ Q + + R + Q AR E+L
Sbjct: 1909 QCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQE 1968
Query: 331 APSESHAGAQPRPRGGPHDAEL 352
A ++HA Q + + AEL
Sbjct: 1969 ALGKAHAALQGKEQHLLEQAEL 1990
Score = 37.0 bits (84), Expect = 0.029
Identities = 43/148 (29%), Positives = 66/148 (44%), Gaps = 20/148 (13%)
Query: 160 LRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEA 219
L+V E EA WE+ E A+LQ A AE A L+ + + ++
Sbjct: 643 LQVDLAEAEKRREALWEKNTHLE--------AQLQKAEEAGAELQADLRDIQEEKEEIQK 694
Query: 220 ELQLAAEAPGPPSPMASATERLHQDLAVQERQSAE-VQGSLALVSR------ALEAAERA 272
+L +E+ + E+LHQ+ QE A VQ ALV L+A ER
Sbjct: 695 KL---SESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERD 751
Query: 273 LQAQAQELEELN--RELRQCNLQQFIQQ 298
Q A++L+ L+ +EL + +L + QQ
Sbjct: 752 RQDLAEQLQGLSSAKELLESSLFEAQQQ 779
Score = 35.8 bits (81), Expect = 0.064
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 36/176 (20%)
Query: 153 TDLRGLELRVQRNAEELG----------------HE--AFWEQELRREQAREREGQARLQ 194
T+L+ L+ ++ +N EE HE A + LRR + + E Q +
Sbjct: 1285 TELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERE 1344
Query: 195 ALSAATAEHAARLQALDA---QARA-------LEAELQLAAEAPGPPSPMASATERLHQD 244
L AA A+++ L A +ARA LE +L+ A A + + Q
Sbjct: 1345 LLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQA 1404
Query: 245 LAVQER----QSAEVQGSLALVSRALEAAE---RALQAQAQELEELNRELRQCNLQ 293
L Q Q +Q +LAL+++ L E L+ Q QELE+ RE+++ L+
Sbjct: 1405 LQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEK-QREMQKAALE 1459
Score = 34.3 bits (77), Expect = 0.19
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 12/135 (8%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
+LR + +E A +Q EQA+E E + R AL + + A L+ D + AL
Sbjct: 1891 DLRAESREQEKALLALQQQ--CAEQAQEHEVETR--ALQDSWLQAQAVLKERDQELEALR 1946
Query: 219 AELQLAAEAPGPPSPMASATE----RLHQDLAVQERQSAEVQGSLALVSRALEAAERALQ 274
AE Q + A A + + H L +E+ E A +SR+LEA+ LQ
Sbjct: 1947 AESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQ----AELSRSLEASTATLQ 2002
Query: 275 AQAQELEELNRELRQ 289
A + +R+L +
Sbjct: 2003 ASLDACQAHSRQLEE 2017
Score = 32.7 bits (73), Expect = 0.54
Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
Query: 176 EQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEAE------LQLAAEAPG 229
E+E + R +E Q ++A+ A E + ++ Q + LE E L+ +
Sbjct: 881 EREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQ-LETEKERVSLLETLLQTQK 939
Query: 230 PPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQE 279
+ + ERL QD+ VQ+ + E G ++ L+ A+R L+ A++
Sbjct: 940 ELADASQQLERLRQDMKVQKLKEQETTG---ILQTQLQEAQRELKEAARQ 986
Score = 32.3 bits (72), Expect = 0.71
Identities = 30/139 (21%), Positives = 58/139 (41%), Gaps = 10/139 (7%)
Query: 155 LRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQA 214
+R LE + L H+ E E + + + GQ + T E A L+
Sbjct: 1510 IRELEKDRETQRNVLEHQLL-ELEKKDQMIESQRGQVQDLKKQLVTLECLAL--ELEENH 1566
Query: 215 RALEAELQLAAEAPGPPSPMASATERL-------HQDLAVQERQSAEVQGSLALVSRALE 267
+E + +L E G A L Q+L Q Q +++ +++R L+
Sbjct: 1567 HKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQ 1626
Query: 268 AAERALQAQAQELEELNRE 286
++ +++Q +++EEL R+
Sbjct: 1627 ERDQEVKSQREQIEELQRQ 1645
Score = 31.2 bits (69), Expect = 1.6
Identities = 29/127 (22%), Positives = 55/127 (43%), Gaps = 22/127 (17%)
Query: 159 ELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALE 218
+LR R+A +L +E E E R QA + +G+ ++ AQ +AL+
Sbjct: 1380 DLRTARSALKLKNEEV-ESERERAQALQEQGELKV------------------AQGKALQ 1420
Query: 219 AELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQ 278
L L + + E L + E+Q + +L L+S L+ + + Q +
Sbjct: 1421 ENLALLTQTL---AEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQE 1477
Query: 279 ELEELNR 285
+++EL +
Sbjct: 1478 QIQELEK 1484
Score = 30.4 bits (67), Expect = 2.7
Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 10/104 (9%)
Query: 176 EQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMA 235
E+E + +R + AL AE R +AL + LEA+LQ A EA
Sbjct: 623 EEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGA------ 676
Query: 236 SATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQE 279
L DL + + E+Q L+ EAA L+ QE
Sbjct: 677 ----ELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQE 716
Score = 29.6 bits (65), Expect = 4.6
Identities = 36/162 (22%), Positives = 62/162 (38%), Gaps = 31/162 (19%)
Query: 153 TDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATA----------- 201
T++ R +++ EL E L+ E A R +L AL+ A A
Sbjct: 564 TEVTAALARAEQSIAELSSS---ENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLL 620
Query: 202 -------EHAARLQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAE 254
+R++A + AL+ +L AEA + L L E AE
Sbjct: 621 QLEEENQSVCSRMEAAEQARNALQVDL---AEAEKRREALWEKNTHLEAQLQKAEEAGAE 677
Query: 255 VQGSLALVSRALEAAERAL-------QAQAQELEELNRELRQ 289
+Q L + E ++ L +A +LE+L++E ++
Sbjct: 678 LQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKR 719
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 42.0 bits (97), Expect = 9e-04
Identities = 69/300 (23%), Positives = 101/300 (33%), Gaps = 46/300 (15%)
Query: 93 GRPSSDSCPPPERCLIRASLPVKPRAALGCEPRKTLTPEPAPSLSRPGPAAPVTPTP--- 149
G P PPPE +P E TP PAP P P+AP P
Sbjct: 777 GPPPGPPTPPPE------DIPAPTEPTPASEATGAPTPPPAP----PSPSAPPPVVPKEE 826
Query: 150 -----GCCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHA 204
+ E + AEEL + +E + + E + + A AE
Sbjct: 827 KEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEAT 886
Query: 205 ARLQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSR 264
A AL A+ + + A++ G P S+ + E AE L+S
Sbjct: 887 AE-GALKAEKKEGGSGRATTAKSSGAPQDSDSSAT-----CSADEVDEAEGGDKNRLLSP 940
Query: 265 ALEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPP-------PPRPDRGPPGTQ 317
+A + +L+Q ++Q AA+PP PPR D P
Sbjct: 941 RPSLLTPTGDPRANASPQKPLDLKQ------LKQRAAAIPPIVTKVHEPPREDAAPTKPA 994
Query: 318 GPLPPAREESLLGAPSESHAGAQPRPR----GGPHDAELLEVAAAPAPEWCPLAAQPQAL 373
P PP + + + G+ PR + P D E + PA AA+ Q L
Sbjct: 995 PPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPA-----FAAEAQKL 1049
Score = 32.0 bits (71), Expect = 0.92
Identities = 75/310 (24%), Positives = 106/310 (34%), Gaps = 57/310 (18%)
Query: 57 ERQLLPQECPVGAQATCGQFASDVQFVLR---RTGPSLAGRPSSDSCPPPERCLIRASLP 113
E LLP+E P A+ + + F+ + R+G A PS S P P P
Sbjct: 1941 EPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRP------LVPP 1994
Query: 114 VKPRAALGCEPRKTLTPE------PAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAE 167
V A + P K L P PAP S P T + ++ LELR
Sbjct: 1995 VSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKP--FSIQELELR------ 2046
Query: 168 ELGHEAFWEQELRREQAREREGQARLQALSAATAEH----AARLQALDAQARALEAELQL 223
LG+ + EG + +S+ + H L+ LD LE EL+
Sbjct: 2047 SLGYHG---------SSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKS--HLEGELR- 2094
Query: 224 AAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEEL 283
P P P+ E H +S L + ++ +R + AQ + E+
Sbjct: 2095 ----PKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVV-TLAQHISEV 2149
Query: 284 NRELRQCNLQQFIQQTGAALPPP---------PRPD-RGPPGTQGPLPPAREESLLGAPS 333
+ Q + QQ A LP P P D R PP PP G+P
Sbjct: 2150 ---ITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPH 2206
Query: 334 ESHAGAQPRP 343
P P
Sbjct: 2207 SEGGKRSPEP 2216
Score = 30.8 bits (68), Expect = 2.1
Identities = 22/65 (33%), Positives = 25/65 (38%), Gaps = 2/65 (3%)
Query: 300 GAALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPR--PRGGPHDAELLEVAA 357
GA PPP P P P P GAP+ A P P P + + E AA
Sbjct: 774 GADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAA 833
Query: 358 APAPE 362
AP E
Sbjct: 834 APPVE 838
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,881,482
Number of Sequences: 37866
Number of extensions: 1126459
Number of successful extensions: 17078
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 237
Number of HSP's successfully gapped in prelim test: 904
Number of HSP's that attempted gapping in prelim test: 11068
Number of HSP's gapped (non-prelim): 6326
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.