Guide to the Human Genome
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Search of human proteins with 4502183

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502183 aquaporin 5 [Homo sapiens]
         (265 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502183 aquaporin 5 [Homo sapiens]                                 519   e-147
gi|4502179 aquaporin 2 [Homo sapiens]                                 348   3e-96
gi|86792455 aquaporin 6 [Homo sapiens]                                286   1e-77
gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]       281   3e-76
gi|4755125 aquaporin 4 isoform b [Homo sapiens]                       238   4e-63
gi|4502181 aquaporin 4 isoform a [Homo sapiens]                       238   4e-63
gi|37694062 aquaporin 1 [Homo sapiens]                                224   8e-59
gi|45446752 aquaporin 8 [Homo sapiens]                                129   2e-30
gi|157266307 aquaporin 9 [Homo sapiens]                                97   2e-20
gi|4826645 aquaporin 3 [Homo sapiens]                                  86   3e-17
gi|4502187 aquaporin 7 [Homo sapiens]                                  79   3e-15
gi|22538420 aquaporin 10 [Homo sapiens]                                58   7e-09
gi|40538880 aquaporin 12A [Homo sapiens]                               38   0.010
gi|156447037 aquaporin 12B [Homo sapiens]                              37   0.023
gi|83921614 cytochrome b5 outer mitochondrial membrane precursor...    32   0.75 
gi|4557727 lipoprotein lipase precursor [Homo sapiens]                 29   4.8  
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    28   6.3  
gi|46410929 solute carrier family 43, member 3 [Homo sapiens]          28   6.3  
gi|41056259 solute carrier family 43, member 3 [Homo sapiens]          28   6.3  
gi|18252047 solute carrier family 43, member 3 [Homo sapiens]          28   6.3  
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    28   8.3  

>gi|4502183 aquaporin 5 [Homo sapiens]
          Length = 265

 Score =  519 bits (1336), Expect = e-147
 Identities = 265/265 (100%), Positives = 265/265 (100%)

Query: 1   MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQAL 60
           MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQAL
Sbjct: 1   MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQAL 60

Query: 61  GPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVN 120
           GPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVN
Sbjct: 61  GPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVN 120

Query: 121 ALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFT 180
           ALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFT
Sbjct: 121 ALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFT 180

Query: 181 GCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIK 240
           GCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIK
Sbjct: 181 GCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIK 240

Query: 241 GTYEPDEDWEEQREERKKTMELTTR 265
           GTYEPDEDWEEQREERKKTMELTTR
Sbjct: 241 GTYEPDEDWEEQREERKKTMELTTR 265


>gi|4502179 aquaporin 2 [Homo sapiens]
          Length = 271

 Score =  348 bits (893), Expect = 3e-96
 Identities = 171/259 (66%), Positives = 213/259 (82%), Gaps = 2/259 (0%)

Query: 4   EVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPV 63
           E+ S+AF +AVFAEFLATL+FVFFGLGSAL WP ALP++LQIA+AFGL IGTL QALG +
Sbjct: 3   ELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALGHI 62

Query: 64  SGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALN 123
           SG HINPA+T+A LVG  +S+LRA FYVAAQL+GA+AGA +L+ + P + RG+LAVNAL+
Sbjct: 63  SGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALS 122

Query: 124 NNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCS 183
           N+TT GQA+ VEL LT QL LCIFASTD RR    G+PALSIG SV LGHL+GI++TGCS
Sbjct: 123 NSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCS 182

Query: 184 MNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTY 243
           MNPARS  PAVV  +F   HWVFW+GP+VGA+L ++LY Y+LFP + SLSER+A++KG  
Sbjct: 183 MNPARSLAPAVVTGKFDD-HWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKG-L 240

Query: 244 EPDEDWEEQREERKKTMEL 262
           EPD DWEE+   R++++EL
Sbjct: 241 EPDTDWEEREVRRRQSVEL 259


>gi|86792455 aquaporin 6 [Homo sapiens]
          Length = 282

 Score =  286 bits (733), Expect = 1e-77
 Identities = 138/236 (58%), Positives = 184/236 (77%), Gaps = 3/236 (1%)

Query: 9   AFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHI 68
           A  +A+FAEFLAT ++VFFG+GS ++WP+ALP++LQIA+ F L      Q     SG H 
Sbjct: 22  AISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAITFNLVTAMAVQVTWKASGAHA 81

Query: 69  NPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQ 128
           NPA+TLA LVG+ ISL RA  YVAAQLVGA  GA +LYGV P + R  L +N + N+ + 
Sbjct: 82  NPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINVVRNSVST 141

Query: 129 GQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPAR 188
           GQA+ VEL+LT QL LC+FASTDSR+TS  GSPA  IG+SV LGHL+GI+FTGCSMNPAR
Sbjct: 142 GQAVAVELLLTLQLVLCVFASTDSRQTS--GSPATMIGISVALGHLIGIHFTGCSMNPAR 199

Query: 189 SFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTYE 244
           SFGPA+++ +F+  HWVFWVGP++GA+LA+++Y ++LFP++ +L++R+AI+ GT E
Sbjct: 200 SFGPAIIIGKFT-VHWVFWVGPLMGALLASLIYNFVLFPDTKTLAQRLAILTGTVE 254


>gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]
          Length = 263

 Score =  281 bits (720), Expect = 3e-76
 Identities = 140/262 (53%), Positives = 190/262 (72%), Gaps = 3/262 (1%)

Query: 4   EVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPV 63
           E+ S +F +A+FAEF ATL +VFFGLGS+L+W      +LQ+A+AFGLA+ TL Q++G +
Sbjct: 3   ELRSASFWRAIFAEFFATLFYVFFGLGSSLRWAPGPLHVLQVAMAFGLALATLVQSVGHI 62

Query: 64  SGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALN 123
           SG H+NPA+T A LVG+Q+SLLRAF Y+AAQL+GA+AGA +LY V P   RGNLA+N L+
Sbjct: 63  SGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAVRGNLALNTLH 122

Query: 124 NNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCS 183
              + GQA  VE+ LT Q  LCIFA+ D RR   +GS AL++G S+ LGHL G+Y+TG  
Sbjct: 123 PAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAG 182

Query: 184 MNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTY 243
           MNPARSF PA++   F+  HWV+WVGPI+G  L ++LY +LLFP   S+SER++++KG  
Sbjct: 183 MNPARSFAPAILTGNFT-NHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISERLSVLKGA- 240

Query: 244 EPDEDWEEQREERKKTMELTTR 265
           +PD     Q E   + +EL T+
Sbjct: 241 KPDVS-NGQPEVTGEPVELNTQ 261


>gi|4755125 aquaporin 4 isoform b [Homo sapiens]
          Length = 301

 Score =  238 bits (607), Expect = 4e-63
 Identities = 132/263 (50%), Positives = 170/263 (64%), Gaps = 12/263 (4%)

Query: 3   KEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSA---LPT-ILQIALAFGLAIGTLAQ 58
           K V + AF KAV AEFLA LIFV   LGS + W      LP  ++ I+L FGL+I T+ Q
Sbjct: 5   KGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQ 64

Query: 59  ALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLA 118
             G +SGGHINPA+T+A++   +IS+ ++ FY+AAQ +GAI GAGILY V P +  G L 
Sbjct: 65  CFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLG 124

Query: 119 VNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIY 178
           V  ++ N T G  ++VELI+TFQL   IFAS DS+RT   GS AL+IG SV +GHL  I 
Sbjct: 125 VTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAIN 184

Query: 179 FTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPN-------SLS 231
           +TG SMNPARSFGPAV+M  +   HW++WVGPI+GAVLA  LY Y+  P+         +
Sbjct: 185 YTGASMNPARSFGPAVIMGNWE-NHWIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEA 243

Query: 232 LSERVAIIKGTYEPDEDWEEQRE 254
            S+     KG+Y   ED   Q E
Sbjct: 244 FSKAAQQTKGSYMEVEDNRSQVE 266


>gi|4502181 aquaporin 4 isoform a [Homo sapiens]
          Length = 323

 Score =  238 bits (607), Expect = 4e-63
 Identities = 132/263 (50%), Positives = 170/263 (64%), Gaps = 12/263 (4%)

Query: 3   KEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSA---LPT-ILQIALAFGLAIGTLAQ 58
           K V + AF KAV AEFLA LIFV   LGS + W      LP  ++ I+L FGL+I T+ Q
Sbjct: 27  KGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQ 86

Query: 59  ALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLA 118
             G +SGGHINPA+T+A++   +IS+ ++ FY+AAQ +GAI GAGILY V P +  G L 
Sbjct: 87  CFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLG 146

Query: 119 VNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIY 178
           V  ++ N T G  ++VELI+TFQL   IFAS DS+RT   GS AL+IG SV +GHL  I 
Sbjct: 147 VTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAIN 206

Query: 179 FTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPN-------SLS 231
           +TG SMNPARSFGPAV+M  +   HW++WVGPI+GAVLA  LY Y+  P+         +
Sbjct: 207 YTGASMNPARSFGPAVIMGNWE-NHWIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEA 265

Query: 232 LSERVAIIKGTYEPDEDWEEQRE 254
            S+     KG+Y   ED   Q E
Sbjct: 266 FSKAAQQTKGSYMEVEDNRSQVE 288


>gi|37694062 aquaporin 1 [Homo sapiens]
          Length = 269

 Score =  224 bits (570), Expect = 8e-59
 Identities = 124/268 (46%), Positives = 167/268 (62%), Gaps = 12/268 (4%)

Query: 1   MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSAL--KWP-----SALPTILQIALAFGLAI 53
           M  E     F +AV AEFLAT +FVF  +GSAL  K+P     +A+   ++++LAFGL+I
Sbjct: 1   MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI 60

Query: 54  GTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNA 113
            TLAQ++G +SG H+NPA+TL LL+  QIS+ RA  Y+ AQ VGAI    IL G+     
Sbjct: 61  ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT 120

Query: 114 RGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGH 173
             +L  N L +    GQ + +E+I T QL LC+ A+TD RR    GS  L+IGLSV LGH
Sbjct: 121 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH 180

Query: 174 LVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLS 233
           L+ I +TGC +NPARSFG AV+ + FS  HW+FWVGP +G  LA ++Y ++L P S  L+
Sbjct: 181 LLAIDYTGCGINPARSFGSAVITHNFS-NHWIFWVGPFIGGALAVLIYDFILAPRSSDLT 239

Query: 234 ERVAIIKG----TYEPDEDWEEQREERK 257
           +RV +        Y+ D D    R E K
Sbjct: 240 DRVKVWTSGQVEEYDLDADDINSRVEMK 267


>gi|45446752 aquaporin 8 [Homo sapiens]
          Length = 261

 Score =  129 bits (325), Expect = 2e-30
 Identities = 80/215 (37%), Positives = 124/215 (57%), Gaps = 8/215 (3%)

Query: 10  FLKAVFAEFLATLIFVFFGLGSALKWPSALPT-ILQIALAFGLAIGTLAQALGPVSGGHI 68
           F++    E L + +F+F G  S ++  +   T +LQ ALA GLA+G +   LG +SGGH 
Sbjct: 34  FVQPCLVELLGSALFIFIGCLSVIE--NGTDTGLLQPALAHGLALGLVIATLGNISGGHF 91

Query: 69  NPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQ 128
           NPA++LA ++   ++L+    Y  +QL+G + GA +   V+P     N +  A      Q
Sbjct: 92  NPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQ 151

Query: 129 GQ---AMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMN 185
           GQ   A+V E+ILT  LAL +     + +T    +P  SIG +VT+  L G   +G  MN
Sbjct: 152 GQVAGALVAEIILTTLLALAVCMGAINEKTKGPLAP-FSIGFAVTVDILAGGPVSGGCMN 210

Query: 186 PARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAIL 220
           PAR+FGPAVV N ++  HW++W+GP++  +L  +L
Sbjct: 211 PARAFGPAVVANHWN-FHWIYWLGPLLAGLLVGLL 244


>gi|157266307 aquaporin 9 [Homo sapiens]
          Length = 295

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 69/251 (27%), Positives = 115/251 (45%), Gaps = 31/251 (12%)

Query: 5   VCSVAFLKAVFAEFLATLIFVFFGLG---SALKWPSALPTILQIALAFGLAIGTLAQALG 61
           V   +  K   +EFL T I +  G G    A+        ++ I + F +A+       G
Sbjct: 17  VLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAG 76

Query: 62  PVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYG-------------- 107
            VSGGHINPA++LA+ +  ++   +  FYV AQ +GA  GA  ++G              
Sbjct: 77  GVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKL 136

Query: 108 -VAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRT-SPVGSPALSI 165
            +   NA  ++         +   A   +++ T  L + +FA  DSR   +P G   ++I
Sbjct: 137 LIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAI 196

Query: 166 G-LSVTLGHLVGIYFTGCSMNPARSFGPAV----------VMNRFSPAHWVFWVGPIVGA 214
           G L + +   +G+  +GC+MNPAR   P +          V    +   W+  VGP+VGA
Sbjct: 197 GLLIIVIASSLGLN-SGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGA 255

Query: 215 VLAAILYFYLL 225
           V+  ++Y  ++
Sbjct: 256 VIGGLIYVLVI 266


>gi|4826645 aquaporin 3 [Homo sapiens]
          Length = 292

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 75/242 (30%), Positives = 110/242 (45%), Gaps = 33/242 (13%)

Query: 11  LKAVFAEFLATLIFVFFGLGSALKWPSALPT---ILQIALAFGLAIGTLAQALGPVSGGH 67
           L+   AE L TLI V FG GS  +   +  T    L I LAFG A+       G VSG H
Sbjct: 22  LRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAH 81

Query: 68  INPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTT 127
           +NPA+T A+    +   ++   Y  AQ +GA  GAGI++G+   +A  + A N L  +  
Sbjct: 82  LNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLY-YDAIWHFADNQLFVSGP 140

Query: 128 QGQAMVV----------------ELILTFQLALCIFASTDS-RRTSPVGSPALSIGLSV- 169
            G A +                 + I T  L +C+ A  D      P G  A ++GL V 
Sbjct: 141 NGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVL 200

Query: 170 TLGHLVGIYFTGCSMNPARSFGP----------AVVMNRFSPAHWVFWVGPIVGAVLAAI 219
            +G  +G + +G ++NPAR FGP          + V        WV  V P++G++    
Sbjct: 201 VIGTSMG-FNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGSIAGVF 259

Query: 220 LY 221
           +Y
Sbjct: 260 VY 261


>gi|4502187 aquaporin 7 [Homo sapiens]
          Length = 342

 Score = 79.3 bits (194), Expect = 3e-15
 Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 32/253 (12%)

Query: 3   KEVCSVAFLKAVFAEFLATLIFVFFGLGSA--LKWPSALPTILQIALAFGLAIGTLAQAL 60
           +E+     ++   AEF++T + + FGLGS   +       + L + L FG  +       
Sbjct: 26  QEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVA 85

Query: 61  GPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGV------------ 108
           G +SG H+N A+T A     ++   +   YV  Q +G+   A  +Y +            
Sbjct: 86  GRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQ 145

Query: 109 ----APLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPV-GSPAL 163
                P+   G  A   L ++ T  +  + E  LT  L LC+FA TD      + G+ AL
Sbjct: 146 LMVTGPVATAGIFA-TYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEAL 204

Query: 164 SIG-LSVTLGHLVGIYFTGCSMNPARSFGPAV----------VMNRFSPAHWVFWVGPIV 212
            IG L V +G  +G+  TG ++NP+R   P +          V +      WV  V P++
Sbjct: 205 VIGILVVIIGVSLGMN-TGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLL 263

Query: 213 GAVLAAILYFYLL 225
           GA L  I+Y   +
Sbjct: 264 GAYLGGIIYLVFI 276


>gi|22538420 aquaporin 10 [Homo sapiens]
          Length = 301

 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 62/240 (25%), Positives = 100/240 (41%), Gaps = 31/240 (12%)

Query: 16  AEFLATLIFVFFGLGSALKWPSALPT---ILQIALAFGLAIGTLAQALGPVSGGHINPAI 72
           AEFL   + +    G+  +  ++  T      + LA  LA+       G VSG H+NPA 
Sbjct: 26  AEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLNPAF 85

Query: 73  TLALLVGNQISLLRAFFYVAAQLVGAIAGAG---ILYGVAPLN-ARGNLAVNALNNNT-- 126
           +LA+ +  ++  ++   Y+  QL+ A   +G   +LY  A  N   GNL V         
Sbjct: 86  SLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGPKETASI 145

Query: 127 ---------TQGQAMVVELILTFQLALCIFASTDSRRTS-PVGSPALSIG-LSVTLGHLV 175
                    +     + +++ T  L + + A  D R    P G   + +G L + LG  +
Sbjct: 146 FATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILALGLSM 205

Query: 176 GIYFTGCSMNPARSFGPAV----------VMNRFSPAHWVFWVGPIVGAVLAAILYFYLL 225
           G    G  +NPAR  GP +          V +  +   WV  V P+VGA +    Y  L+
Sbjct: 206 GAN-CGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGATVGTATYQLLV 264


>gi|40538880 aquaporin 12A [Homo sapiens]
          Length = 295

 Score = 37.7 bits (86), Expect = 0.010
 Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 13/168 (7%)

Query: 63  VSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGIL-----YGVAPLNARGNL 117
           + G   NP ++L   +  + SL      +AAQ +G  A   ++     + ++ L+   +L
Sbjct: 75  LDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCWAWELSDLHLLQSL 134

Query: 118 AVNALNN--NTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLV 175
              + ++   T+     +VE    F    C   +    R SP      ++ L VT+    
Sbjct: 135 MAQSCSSALRTSVPHGALVEAACAF----CFHLTLLHLRHSPPAYSGPAVALLVTVTAYT 190

Query: 176 GIYFTGCSMNPARSFGPAVVMNRFSPAHWV--FWVGPIVGAVLAAILY 221
              FT    NPA +       +  +   +V  +W+GP+ G VLA +L+
Sbjct: 191 AGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLH 238


>gi|156447037 aquaporin 12B [Homo sapiens]
          Length = 307

 Score = 36.6 bits (83), Expect = 0.023
 Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 13/168 (7%)

Query: 63  VSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGIL-----YGVAPLNARGNL 117
           + G   NP ++L   +  + SL      +AAQ +G  A   +      + ++ L+   +L
Sbjct: 87  LDGASANPTVSLQEFLMAEESLPGTLLKLAAQGLGMQAACTLTRLCWAWELSDLHLLQSL 146

Query: 118 AVNALNN--NTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLV 175
              + ++   T+     +VE    F    C   +    R SP      ++ L VT+    
Sbjct: 147 MAQSCSSALRTSVPHGALVEAACAF----CFHLTLLHLRHSPPAYSGPAVALLVTVTAYT 202

Query: 176 GIYFTGCSMNPARSFGPAVVMNRFSPAHWV--FWVGPIVGAVLAAILY 221
              FT    NPA +       +  +   +V  +W+GP+ G VLA +L+
Sbjct: 203 AGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLH 250


>gi|83921614 cytochrome b5 outer mitochondrial membrane precursor
           [Homo sapiens]
          Length = 150

 Score = 31.6 bits (70), Expect = 0.75
 Identities = 11/20 (55%), Positives = 14/20 (70%)

Query: 204 WVFWVGPIVGAVLAAILYFY 223
           W +W+ PI+GAVL   LY Y
Sbjct: 123 WAYWILPIIGAVLLGFLYRY 142


>gi|4557727 lipoprotein lipase precursor [Homo sapiens]
          Length = 475

 Score = 28.9 bits (63), Expect = 4.8
 Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)

Query: 151 DSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAV 194
           D   T   GSP  SIG+   +GH V IY  G +  P  + G A+
Sbjct: 207 DVLHTFTRGSPGRSIGIQKPVGH-VDIYPNGGTFQPGCNIGEAI 249


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
           theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 5/34 (14%)

Query: 234 ERVAIIKGTYEP----DED-WEEQREERKKTMEL 262
           E + +IK  YE     D D WE+Q EER  TM+L
Sbjct: 705 EEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQL 738


>gi|46410929 solute carrier family 43, member 3 [Homo sapiens]
          Length = 491

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 28/97 (28%), Positives = 39/97 (40%), Gaps = 11/97 (11%)

Query: 7   SVAFLKAVFAEFLATLIFVFFGLGSALKWPSALP-----------TILQIALAFGLAIGT 55
           +VA L A+F    ATLI  F   GSA+    A+P           T LQI   FG    T
Sbjct: 98  TVARLIAIFFYTTATLIIAFTSAGSAVLLFLAMPMLTIGGILFLITNLQIGNLFGQHRST 157

Query: 56  LAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVA 92
           +               + + LL    ISL  +F +++
Sbjct: 158 IITLYNGAFDSSSAVFLIIKLLYEKGISLRASFIFIS 194


>gi|41056259 solute carrier family 43, member 3 [Homo sapiens]
          Length = 491

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 28/97 (28%), Positives = 39/97 (40%), Gaps = 11/97 (11%)

Query: 7   SVAFLKAVFAEFLATLIFVFFGLGSALKWPSALP-----------TILQIALAFGLAIGT 55
           +VA L A+F    ATLI  F   GSA+    A+P           T LQI   FG    T
Sbjct: 98  TVARLIAIFFYTTATLIIAFTSAGSAVLLFLAMPMLTIGGILFLITNLQIGNLFGQHRST 157

Query: 56  LAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVA 92
           +               + + LL    ISL  +F +++
Sbjct: 158 IITLYNGAFDSSSAVFLIIKLLYEKGISLRASFIFIS 194


>gi|18252047 solute carrier family 43, member 3 [Homo sapiens]
          Length = 491

 Score = 28.5 bits (62), Expect = 6.3
 Identities = 28/97 (28%), Positives = 39/97 (40%), Gaps = 11/97 (11%)

Query: 7   SVAFLKAVFAEFLATLIFVFFGLGSALKWPSALP-----------TILQIALAFGLAIGT 55
           +VA L A+F    ATLI  F   GSA+    A+P           T LQI   FG    T
Sbjct: 98  TVARLIAIFFYTTATLIIAFTSAGSAVLLFLAMPMLTIGGILFLITNLQIGNLFGQHRST 157

Query: 56  LAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVA 92
           +               + + LL    ISL  +F +++
Sbjct: 158 IITLYNGAFDSSSAVFLIIKLLYEKGISLRASFIFIS 194


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
           [Homo sapiens]
          Length = 1336

 Score = 28.1 bits (61), Expect = 8.3
 Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 3/78 (3%)

Query: 153 RRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFG---PAVVMNRFSPAHWVFWVG 209
           R    +GS  ++   S  +   V    TG S+  ARS G   P+  +  +SPA WV    
Sbjct: 532 RADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFV 591

Query: 210 PIVGAVLAAILYFYLLFP 227
             +  V   +  F  L P
Sbjct: 592 MCLTVVAVTVFIFEYLSP 609


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,940,384
Number of Sequences: 37866
Number of extensions: 368557
Number of successful extensions: 1361
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1313
Number of HSP's gapped (non-prelim): 23
length of query: 265
length of database: 18,247,518
effective HSP length: 100
effective length of query: 165
effective length of database: 14,460,918
effective search space: 2386051470
effective search space used: 2386051470
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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