Search of human proteins with 45006986

Search of human proteins with 45006986

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45006986 small inducible cytokine subfamily E, member 1
isoform a precursor [Homo sapiens]
         (312 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215490011 small inducible cytokine subfamily E, member 1 isof...   611   e-175
gi|215490009 small inducible cytokine subfamily E, member 1 isof...   611   e-175
gi|45006986 small inducible cytokine subfamily E, member 1 isofo...   611   e-175
gi|4507947 tyrosyl-tRNA synthetase [Homo sapiens]                     170   2e-42
gi|116008447 CAP-GLY domain containing linker protein 2 isoform ...    40   0.003
gi|14702162 CAP-GLY domain containing linker protein 2 isoform 2...    40   0.003
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    40   0.003
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             40   0.003
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]             40   0.003
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]             40   0.003
gi|122891870 melanoma inhibitory activity family, member 3 [Homo...    39   0.005
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    39   0.005
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    39   0.006
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    38   0.010
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    38   0.010
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     38   0.010
gi|16262452 cingulin [Homo sapiens]                                    38   0.013
gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens]                38   0.013
gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens]                38   0.013
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 37   0.017
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    37   0.017
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    37   0.017
gi|71061468 centromere protein E [Homo sapiens]                        37   0.023
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      37   0.029
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                37   0.029
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ...    36   0.038
gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan...    36   0.038
gi|71284108 nudE nuclear distribution gene E homolog (A. nidulan...    36   0.038
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     36   0.038
gi|33946313 ninein isoform 4 [Homo sapiens]                            36   0.038

>gi|215490011 small inducible cytokine subfamily E, member 1 isoform
           b precursor [Homo sapiens]
          Length = 336

 Score =  611 bits (1576), Expect = e-175
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 1   MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE 60
           MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE
Sbjct: 25  MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE 84

Query: 61  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 120
           ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE
Sbjct: 85  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 144

Query: 121 KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD 180
           KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD
Sbjct: 145 KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD 204

Query: 181 VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA 240
           VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA
Sbjct: 205 VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA 264

Query: 241 PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV 300
           PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV
Sbjct: 265 PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV 324

Query: 301 CRAQTMSNSGIK 312
           CRAQTMSNSGIK
Sbjct: 325 CRAQTMSNSGIK 336


>gi|215490009 small inducible cytokine subfamily E, member 1 isoform
           a precursor [Homo sapiens]
          Length = 312

 Score =  611 bits (1576), Expect = e-175
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 1   MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE 60
           MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE
Sbjct: 1   MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE 60

Query: 61  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 120
           ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE
Sbjct: 61  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 120

Query: 121 KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD 180
           KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD
Sbjct: 121 KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD 180

Query: 181 VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA 240
           VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA
Sbjct: 181 VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA 240

Query: 241 PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV 300
           PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV
Sbjct: 241 PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV 300

Query: 301 CRAQTMSNSGIK 312
           CRAQTMSNSGIK
Sbjct: 301 CRAQTMSNSGIK 312


>gi|45006986 small inducible cytokine subfamily E, member 1 isoform
           a precursor [Homo sapiens]
          Length = 312

 Score =  611 bits (1576), Expect = e-175
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 1   MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE 60
           MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE
Sbjct: 1   MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE 60

Query: 61  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 120
           ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE
Sbjct: 61  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 120

Query: 121 KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD 180
           KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD
Sbjct: 121 KKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVD 180

Query: 181 VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA 240
           VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA
Sbjct: 181 VGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILA 240

Query: 241 PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV 300
           PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV
Sbjct: 241 PPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGV 300

Query: 301 CRAQTMSNSGIK 312
           CRAQTMSNSGIK
Sbjct: 301 CRAQTMSNSGIK 312


>gi|4507947 tyrosyl-tRNA synthetase [Homo sapiens]
          Length = 528

 Score =  170 bits (430), Expect = 2e-42
 Identities = 86/171 (50%), Positives = 121/171 (70%), Gaps = 6/171 (3%)

Query: 132 EKKEKKQQSIAGSADSKPIDV--SRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTV 189
           +  ++K  +   + +S+P +V  SRLD+R+G IIT  KHPDADSLYVE++DVGE  PRTV
Sbjct: 343 DPSKQKPMAKGPAKNSEPEEVIPSRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTV 402

Query: 190 VSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSP---EKIEILAPPNGSV 246
           VSGLV  VP E++Q+R+V++LCNLKP KMRGV SQ M++CAS      ++E L PP GS 
Sbjct: 403 VSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVESQGMLLCASIEGINRQVEPLDPPAGSA 462

Query: 247 PGDRITFDAF-PGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVK 296
           PG+ +    +  G+PD+EL PKKK++E++Q D   ++EC+A +K   F  K
Sbjct: 463 PGEHVFVKGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWKQTNFMTK 513


>gi|116008447 CAP-GLY domain containing linker protein 2 isoform 1
           [Homo sapiens]
          Length = 1046

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 35/150 (23%), Positives = 75/150 (50%), Gaps = 28/150 (18%)

Query: 8   LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELI 67
           L++L+ +     Q IE+LK+Q+SL ++K +      + ++L+   A+ K+E+E L+++L+
Sbjct: 735 LEKLDVEYRGQAQAIEFLKEQISLAEKKML------DYERLQRAEAQGKQEVESLREKLL 788

Query: 68  QAEIQ-NGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEK 126
            AE +   V+ +     T +  ++ +SE  I+          TKE ++G           
Sbjct: 789 VAENRLQAVEALCSSQHTHMIESNDISEETIR----------TKETVEG----------- 827

Query: 127 IEKKGEKKEKKQQSIAGSADSKPIDVSRLD 156
           ++ K  K++K+  ++    +     VS L+
Sbjct: 828 LQDKLNKRDKEVTALTSQTEMLRAQVSALE 857



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 11/125 (8%)

Query: 30  SLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELI--QAEIQNGVKQIPFPSGTPLH 87
           SLL EKA  +  LRE    R+     K  + +L++EL   + EI+  ++Q    SG P  
Sbjct: 476 SLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELTLRRGEIEE-LQQCLLHSGPPPP 534

Query: 88  ANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAK------EKIEKKGEKKEKKQQSI 141
            +   +E  I       +S+  + Q + G   +K  K       +++K     EK  Q +
Sbjct: 535 DHPDAAE--ILRLRERLLSASKEHQRESGVLRDKYEKALKAYQAEVDKLRAANEKYAQEV 592

Query: 142 AGSAD 146
           AG  D
Sbjct: 593 AGLKD 597


>gi|14702162 CAP-GLY domain containing linker protein 2 isoform 2
           [Homo sapiens]
          Length = 1011

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 35/150 (23%), Positives = 75/150 (50%), Gaps = 28/150 (18%)

Query: 8   LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELI 67
           L++L+ +     Q IE+LK+Q+SL ++K +      + ++L+   A+ K+E+E L+++L+
Sbjct: 700 LEKLDVEYRGQAQAIEFLKEQISLAEKKML------DYERLQRAEAQGKQEVESLREKLL 753

Query: 68  QAEIQ-NGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEK 126
            AE +   V+ +     T +  ++ +SE  I+          TKE ++G           
Sbjct: 754 VAENRLQAVEALCSSQHTHMIESNDISEETIR----------TKETVEG----------- 792

Query: 127 IEKKGEKKEKKQQSIAGSADSKPIDVSRLD 156
           ++ K  K++K+  ++    +     VS L+
Sbjct: 793 LQDKLNKRDKEVTALTSQTEMLRAQVSALE 822


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 29/111 (26%), Positives = 55/111 (49%), Gaps = 8/111 (7%)

Query: 30  SLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHAN 89
           S +K    L+   +E+++ R+EN + K+E E+L+++ ++ + +  ++++       L   
Sbjct: 518 SFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKV 577

Query: 90  SMVSENVIQSTAVTTVSSGTKEQI--KGGTGDEKKAKEKIEKKGEKKEKKQ 138
               E V Q      +    K+QI  K    DEK  K K E+  E+K KK+
Sbjct: 578 LQARERVEQ------MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK 622


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 32/171 (18%)

Query: 34  EKAILQAT-LREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMV 92
           +KA+ +A  L E  KLR E A+++K++EE  ++     +Q   ++     G  L   S+ 
Sbjct: 96  KKAVEEAERLSESLKLRYEEAEVRKKLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSL- 154

Query: 93  SENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK-KGEKKEKKQQSIAGSADSKPID 151
            ENV+ S                        K+K +K  GEK EK +    G+  +K + 
Sbjct: 155 -ENVLDS------------------------KDKTQKSNGEKNEKCETKEKGAITAKELY 189

Query: 152 VSRLDLRIGCII-TARKHPD-ADSLYVEEVDVGE--IAPRTVVSGLVNHVP 198
               D  I  II  AR+  D  DS  +  + V E  I+P    S +  H+P
Sbjct: 190 TMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 32/171 (18%)

Query: 34  EKAILQAT-LREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMV 92
           +KA+ +A  L E  KLR E A+++K++EE  ++     +Q   ++     G  L   S+ 
Sbjct: 96  KKAVEEAERLSESLKLRYEEAEVRKKLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSL- 154

Query: 93  SENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK-KGEKKEKKQQSIAGSADSKPID 151
            ENV+ S                        K+K +K  GEK EK +    G+  +K + 
Sbjct: 155 -ENVLDS------------------------KDKTQKSNGEKNEKCETKEKGAITAKELY 189

Query: 152 VSRLDLRIGCII-TARKHPD-ADSLYVEEVDVGE--IAPRTVVSGLVNHVP 198
               D  I  II  AR+  D  DS  +  + V E  I+P    S +  H+P
Sbjct: 190 TMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 32/171 (18%)

Query: 34  EKAILQAT-LREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMV 92
           +KA+ +A  L E  KLR E A+++K++EE  ++     +Q   ++     G  L   S+ 
Sbjct: 96  KKAVEEAERLSESLKLRYEEAEVRKKLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSL- 154

Query: 93  SENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK-KGEKKEKKQQSIAGSADSKPID 151
            ENV+ S                        K+K +K  GEK EK +    G+  +K + 
Sbjct: 155 -ENVLDS------------------------KDKTQKSNGEKNEKCETKEKGAITAKELY 189

Query: 152 VSRLDLRIGCII-TARKHPD-ADSLYVEEVDVGE--IAPRTVVSGLVNHVP 198
               D  I  II  AR+  D  DS  +  + V E  I+P    S +  H+P
Sbjct: 190 TMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240


>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
            sapiens]
          Length = 1907

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 30/170 (17%)

Query: 16   AEADQIIEYLKQQVSLLKEK------AILQATLREEK------KLRVENAKLKKEIEELK 63
            +E  + IE LK  +S+   +      A+ +A L EEK      +++ ENA+LKK+ E+L+
Sbjct: 1305 SENKKSIEKLKDVISMNASEFSEVQIALNEAKLSEEKVKSECHRVQEENARLKKKKEQLQ 1364

Query: 64   QEL-----IQAEIQNGVKQIPFPSG------TPLHANSMVSENVIQSTAVTTVSSGTKEQ 112
            QE+     + AE+   +K             T    N     N I    +    S ++ Q
Sbjct: 1365 QEIEDWSKLHAELSEQIKSFEKSQKDLEVALTHKDDNINALTNCITQLNLLECESESEGQ 1424

Query: 113  IKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCI 162
             KGG   ++ A  ++   G++ EK +  I      + +DVSR    I  +
Sbjct: 1425 NKGGNDSDELANGEV--GGDRNEKMKNQI-----KQMMDVSRTQTAISVV 1467


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 36/150 (24%), Positives = 63/150 (42%), Gaps = 24/150 (16%)

Query: 26  KQQVSLLKEKAILQATLREEKKLRVEN-AKLKKEIEELKQELIQAEIQNGVKQIPFPSGT 84
           K +  + K K  ++    E++K  +EN  +LKKEIEE+KQ   +  +++       P+  
Sbjct: 155 KLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGK-KWSLEDDDDDEDDPAEA 213

Query: 85  PLHANSMVSE-----NVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKI------------ 127
               N M  E     +         V       +KGG G+EKK+   +            
Sbjct: 214 EKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKA 273

Query: 128 -----EKKGEKKEKKQQSIAGSADSKPIDV 152
                +KKGE  E  Q ++  S++ + +D+
Sbjct: 274 VVDSDKKKGELMENDQDAMEYSSEEEEVDL 303


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 14/134 (10%)

Query: 13  QKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQ 72
           + G E D     +K       EK   +   R+E+K ++   K K+E+E  K++    + +
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKD----QSK 268

Query: 73  NGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGD---EKKAKEKIEK 129
               Q  F   T       V   V   T V   S    E       D   +KK K+K +K
Sbjct: 269 QKESQRKFEEET-------VKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKK 321

Query: 130 KGEKKEKKQQSIAG 143
           KGEK+EK+++   G
Sbjct: 322 KGEKEEKEKEKKKG 335


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 38/173 (21%), Positives = 80/173 (46%), Gaps = 21/173 (12%)

Query: 8   LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLR-EEKKLRVENAKLKKEIEELK--- 63
           L+ LE++ ++ D+    L++ V  LK  ++  A L+ E K+L  E  +LKK +E LK   
Sbjct: 689 LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF 748

Query: 64  ----------------QELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSS 107
                            + +Q  ++N  K+I     + L    M ++ + ++     +SS
Sbjct: 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQ-QLESELQDLEMENQTLQKNLEELKISS 807

Query: 108 GTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIG 160
              EQ++      ++   ++EK  ++ EK+ + +   A+ K   +   +++IG
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 13/81 (16%)

Query: 3   NNDAVLKRLEQKGAEADQIIEYLKQ--QVS-------LLKEKAILQATLREEK----KLR 49
           N++  +K LEQ+    +Q +  L+Q  Q+S       + KE  IL  +++E      K+ 
Sbjct: 548 NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIE 607

Query: 50  VENAKLKKEIEELKQELIQAE 70
            E  ++KKE+E  K++  +AE
Sbjct: 608 FEKRQIKKELEHYKEKGERAE 628


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 38/173 (21%), Positives = 80/173 (46%), Gaps = 21/173 (12%)

Query: 8   LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLR-EEKKLRVENAKLKKEIEELK--- 63
           L+ LE++ ++ D+    L++ V  LK  ++  A L+ E K+L  E  +LKK +E LK   
Sbjct: 689 LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF 748

Query: 64  ----------------QELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSS 107
                            + +Q  ++N  K+I     + L    M ++ + ++     +SS
Sbjct: 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQ-QLESELQDLEMENQTLQKNLEELKISS 807

Query: 108 GTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIG 160
              EQ++      ++   ++EK  ++ EK+ + +   A+ K   +   +++IG
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 13/81 (16%)

Query: 3   NNDAVLKRLEQKGAEADQIIEYLKQ--QVS-------LLKEKAILQATLREEK----KLR 49
           N++  +K LEQ+    +Q +  L+Q  Q+S       + KE  IL  +++E      K+ 
Sbjct: 548 NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIE 607

Query: 50  VENAKLKKEIEELKQELIQAE 70
            E  ++KKE+E  K++  +AE
Sbjct: 608 FEKRQIKKELEHYKEKGERAE 628


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 37/114 (32%), Positives = 56/114 (49%), Gaps = 13/114 (11%)

Query: 26   KQQVSLLKEKAI-LQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGT 84
            ++++  +K+KA  +Q TL+  KKL  + AKLKKE+E    EL Q E Q   K +      
Sbjct: 953  EKKMEKVKQKAKEMQETLK--KKLLDQEAKLKKELENTALELSQKEKQFNAKMLEM---- 1006

Query: 85   PLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQ 138
               ANS        S AV+ + +  KEQI+  T   ++    +    EKK  +Q
Sbjct: 1007 -AQANSAGI-----SDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQ 1054



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 34/158 (21%), Positives = 70/158 (44%), Gaps = 24/158 (15%)

Query: 8    LKRLEQKGAEADQII-------EYLKQQVSLLKEKAILQAT----LREEKK--------L 48
            L+  EQ+ AE  Q I       E + ++++ LKE+ + Q T    L+E+ K        L
Sbjct: 1066 LQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSL 1125

Query: 49   RVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSG 108
              +  KLK  +E+L     + ++   +K+  F     +    +  E+  + + +T+    
Sbjct: 1126 AQDETKLKAHLEKL-----EVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKT 1180

Query: 109  TKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSAD 146
            T E+ +      +K+ + +E K  + +K  + +A   D
Sbjct: 1181 TDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLD 1218



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 40/185 (21%), Positives = 79/185 (42%), Gaps = 24/185 (12%)

Query: 17  EADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVK 76
           E DQ I  L+ QVSLLK++            + V+  K   ++E   +   + E      
Sbjct: 216 EKDQYISVLQTQVSLLKQRL-------RNGPMNVDVLKPLPQLEPQAEVFTKEENPESDG 268

Query: 77  QIPFPSGT------PLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKK 130
           +     GT       L       EN+++    T  S   KEQ    T +++  +E+++++
Sbjct: 269 EPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSH--KEQCTLLTSEKEALQEQLDER 326

Query: 131 GEKKEK--------KQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVG 182
            ++ EK        K + I    D+K + + +L+   G +I   K    ++L ++E ++ 
Sbjct: 327 LQELEKIKDLHMAEKTKLITQLRDAKNL-IEQLEQDKGMVIAETKRQMHETLEMKEEEIA 385

Query: 183 EIAPR 187
           ++  R
Sbjct: 386 QLRSR 390


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 17/120 (14%)

Query: 22   IEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFP 81
            +  L+ Q  LL+E+  LQA  RE+  L+  N KL+++++EL  + I+ E Q         
Sbjct: 1047 LSQLESQNQLLQER--LQAEEREKTVLQSTNRKLERKVKELSIQ-IEDERQ--------- 1094

Query: 82   SGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSI 141
                 H N    +  ++  A+       +E+I+   G  KKA+ ++E++ E  E+ Q  I
Sbjct: 1095 -----HVNDQKDQLSLRVKALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARI 1149



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 25/130 (19%), Positives = 61/130 (46%), Gaps = 15/130 (11%)

Query: 31  LLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANS 90
           L K+ A+L+      ++L  +N +L+K +++L+Q+  +A   +  K +     T L    
Sbjct: 662 LEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEA---SKAKMVAEAEATVLGQRR 718

Query: 91  MVSENVIQSTAVTTVS-----SGTKEQIK-------GGTGDEKKAKEKIEKKGEKKEKKQ 138
              E  ++ T            G ++Q+K       GG   E + ++K+++   +K++ +
Sbjct: 719 AAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLE 778

Query: 139 QSIAGSADSK 148
           +++  S + +
Sbjct: 779 EALNASQEEE 788


>gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens]
          Length = 567

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 34/139 (24%), Positives = 68/139 (48%), Gaps = 6/139 (4%)

Query: 8   LKRLEQKGAEADQII-EYLKQQVSLLKEKAILQATLREEKK----LRVENAKLKKEIEEL 62
           ++RL  +  +A Q   E  +Q  +LL E  +L+    E ++    L+    +L  ++EEL
Sbjct: 424 IQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEEL 483

Query: 63  KQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQST-AVTTVSSGTKEQIKGGTGDEK 121
            + L + E +   +    P  +P H         ++ST A +T +   ++ + G  GD +
Sbjct: 484 MKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHCPQDSLSGVGGDVQ 543

Query: 122 KAKEKIEKKGEKKEKKQQS 140
           +A  + E+  E++E+K Q+
Sbjct: 544 EAFAQAEEGAEEEEEKMQN 562


>gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens]
          Length = 597

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 34/139 (24%), Positives = 68/139 (48%), Gaps = 6/139 (4%)

Query: 8   LKRLEQKGAEADQII-EYLKQQVSLLKEKAILQATLREEKK----LRVENAKLKKEIEEL 62
           ++RL  +  +A Q   E  +Q  +LL E  +L+    E ++    L+    +L  ++EEL
Sbjct: 454 IQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEEL 513

Query: 63  KQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQST-AVTTVSSGTKEQIKGGTGDEK 121
            + L + E +   +    P  +P H         ++ST A +T +   ++ + G  GD +
Sbjct: 514 MKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHCPQDSLSGVGGDVQ 573

Query: 122 KAKEKIEKKGEKKEKKQQS 140
           +A  + E+  E++E+K Q+
Sbjct: 574 EAFAQAEEGAEEEEEKMQN 592


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 43/176 (24%), Positives = 79/176 (44%), Gaps = 14/176 (7%)

Query: 9   KRLEQKGAEADQIIEYLKQQVSLLKEKAIL-QATLREEKKLRVENAKLKKEIEELKQELI 67
           K+LEQK  E + + + L+++  + ++ A+  +    E  KLR EN +LKK+ E+L Q++I
Sbjct: 122 KQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDII 181

Query: 68  QAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKI 127
             +     KQI     T L      S+   Q +          ++I+  T    +A EKI
Sbjct: 182 DYQ-----KQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLT----EANEKI 232

Query: 128 EKKGEKKEKKQQSIAGSADSKPIDVSRLDLRI----GCIITARKHPDADSLYVEEV 179
           E + ++  K  +      +    + +R+   +      I   +K  D   L V+E+
Sbjct: 233 EVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQEL 288



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 19/151 (12%)

Query: 31   LLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHAN- 89
            L K++      LRE++++  EN +LK++I+ L   L                G PL  N 
Sbjct: 1826 LQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGL---------------QGKPLTDNK 1870

Query: 90   -SMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK--KGEKKEKKQQSIAGSAD 146
             S++ E   +   +     G  E++      EK AKE++ +  +G+K + K + I     
Sbjct: 1871 QSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLK 1930

Query: 147  SKPIDVSRLDLRIGCIITARKHPDADSLYVE 177
             K  +V  L  ++  +       D + L ++
Sbjct: 1931 EKEGEVFTLTKQLNTLKDLFAKADKEKLTLQ 1961



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 35/121 (28%), Positives = 51/121 (42%), Gaps = 13/121 (10%)

Query: 8    LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELI 67
            LK LE   A+ +Q I  LKQ V         +AT RE+K +   N  L+++I+ LK    
Sbjct: 2279 LKELETDIAKKNQSITDLKQLVK--------EATEREQK-VNKYNEDLEQQIKILKHVPE 2329

Query: 68   QAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKI 127
             AE + G+K+         H        +I         SG +  I     D  + KEKI
Sbjct: 2330 GAETEQGLKRELQVLRLANHQLDKEKAELIHQIEANKDQSGAESTIP----DADQLKEKI 2385

Query: 128  E 128
            +
Sbjct: 2386 K 2386



 Score = 28.5 bits (62), Expect = 8.0
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 7/94 (7%)

Query: 8   LKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKL-----RVENAKLKKEIEEL 62
           + +LE K ++     E L+++V L  +  I     R  K L     R EN  L KEIE L
Sbjct: 486 INKLELKISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESL 545

Query: 63  KQELIQAEIQNGVKQIPFPSGTPLHANSMVSENV 96
           ++E  + +++  ++Q+    G     + + +E++
Sbjct: 546 EEE--RLDLKKKIRQMAQERGKRSATSGLTTEDL 577


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 21/159 (13%)

Query: 2    ANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE- 60
            A  +A  + L+   AE D++    K ++ L ++   L+ +L +EKKLR++  + K+++E 
Sbjct: 1004 ALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEG 1063

Query: 61   --ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTG 118
              +L QE I  +I+N  +Q+          +  + +   +   ++ + S  +++   G  
Sbjct: 1064 DLKLAQESIM-DIENEKQQL----------DEKLKKKEFE---ISNLQSKIEDEQALGIQ 1109

Query: 119  DEKKAKE---KIEKKGEKKEKKQQSIAGSADSKPIDVSR 154
             +KK KE   +IE+  E+ E ++ S A  A+ +  D+SR
Sbjct: 1110 LQKKIKELQARIEELEEEIEAERASRA-KAEKQRSDLSR 1147


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 21/159 (13%)

Query: 2    ANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIE- 60
            A  +A  + L+   AE D++    K ++ L ++   L+ +L +EKKLR++  + K+++E 
Sbjct: 1004 ALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEG 1063

Query: 61   --ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTG 118
              +L QE I  +I+N  +Q+          +  + +   +   ++ + S  +++   G  
Sbjct: 1064 DLKLAQESIM-DIENEKQQL----------DEKLKKKEFE---ISNLQSKIEDEQALGIQ 1109

Query: 119  DEKKAKE---KIEKKGEKKEKKQQSIAGSADSKPIDVSR 154
             +KK KE   +IE+  E+ E ++ S A  A+ +  D+SR
Sbjct: 1110 LQKKIKELQARIEELEEEIEAERASRA-KAEKQRSDLSR 1147


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 38/162 (23%), Positives = 76/162 (46%), Gaps = 19/162 (11%)

Query: 18   ADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQ 77
            A ++ E L++  S++KE+  L+   R E+ L++E  +LK+ ++E K      EIQ  +K 
Sbjct: 1874 AQKLHENLEEMKSVMKERDNLR---RVEETLKLERDQLKESLQETKAR--DLEIQQELKT 1928

Query: 78   IPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKK 137
                S         + E + + T           QI     D  K+K++++KK ++ +KK
Sbjct: 1929 ARMLSKEHKETVDKLREKISEKTI----------QISDIQKDLDKSKDELQKKIQELQKK 1978

Query: 138  QQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEV 179
            +  +    +    DV+    +I  +   +K  +A +L ++ V
Sbjct: 1979 ELQLLRVKE----DVNMSHKKINEMEQLKKQFEAQNLSMQSV 2016



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 16/66 (24%), Positives = 37/66 (56%), Gaps = 12/66 (18%)

Query: 7    VLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQEL 66
            ++ +L+ K  E+++ +E  K+ + +L++K  L A               K+EIE+LK +L
Sbjct: 2417 IIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAK------------PYKEEIEDLKMKL 2464

Query: 67   IQAEIQ 72
            ++ +++
Sbjct: 2465 VKIDLE 2470


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 36.6 bits (83), Expect = 0.029
 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 29/144 (20%)

Query: 25  LKQQVSLLKEKAILQATLREEKKL-RVENAKLKKEIEELKQELIQAEI-QNGVKQIPFPS 82
           +K +VSL+K K       RE+++L R E  K K+E   LKQ++ Q+   Q G+KQ+P  S
Sbjct: 558 IKDRVSLIKRK-------REQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSAS 610

Query: 83  -GTPLHANSMVSENV----------------IQSTAVTTVSSGTKEQIKGGTGDEKKAKE 125
            G P  + +  S +                  Q  +++ +S GT   +  G G     + 
Sbjct: 611 TGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGT---VDSGQGSSVFTES 667

Query: 126 KIEKKGEKKEKKQQSIAGSADSKP 149
           ++  +       Q   A S  + P
Sbjct: 668 RVSSQQTVSYGSQHEQAHSTGTVP 691


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 36.6 bits (83), Expect = 0.029
 Identities = 33/145 (22%), Positives = 73/145 (50%), Gaps = 10/145 (6%)

Query: 6   AVLKRLEQKGAEADQIIEYLKQQVSLLK---EKAILQATLREEKKLRVENAKLKKEI--E 60
           A+ + L Q   + ++++  L+++ S L+    +A  +AT+  E++ R+E  +L++E+  +
Sbjct: 743 ALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQ 802

Query: 61  ELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDE 120
            L+  L  AE      +   P  T  H  S + E + Q   ++   SG +++++    + 
Sbjct: 803 GLEGSLRVAEQAQEALEQQLP--TLRHERSQLQEQLAQ---LSRQLSGREQELEQARREA 857

Query: 121 KKAKEKIEKKGEKKEKKQQSIAGSA 145
           ++  E +E+   +KE   +  AG A
Sbjct: 858 QRQVEALERAAREKEALAKEHAGLA 882


>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
           isoform 1 [Homo sapiens]
          Length = 1112

 Score = 36.2 bits (82), Expect = 0.038
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 2/119 (1%)

Query: 34  EKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVS 93
           EK   +   +E+K    E  K KK+ +E K E +   +       P P+  P+ +     
Sbjct: 747 EKKSKKPKKKEKKHKEKERDKEKKKEKEKKAEDLDFWLSTTPPPAPAPAPAPVPSTDECE 806

Query: 94  ENVIQSTAVTTVSSGTKEQIKGGTGDEKK-AKEKIEK-KGEKKEKKQQSIAGSADSKPI 150
           +   ++      + G  +  K     +KK  KEK E+ KG+KK KKQ   +  A  +P+
Sbjct: 807 DAKTEAQGEEDDAEGQDQDKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAGEPV 865


>gi|13540600 nudE nuclear distribution gene E homolog (A.
           nidulans)-like 1 isoform B [Homo sapiens]
          Length = 345

 Score = 36.2 bits (82), Expect = 0.038
 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 1/80 (1%)

Query: 32  LKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSM 91
           ++  A L++ L E++ L V   +LK E  +L+QEL   E Q  V +   PS   L    M
Sbjct: 147 IERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKM 206

Query: 92  VSE-NVIQSTAVTTVSSGTK 110
            S      S   T V  GT+
Sbjct: 207 DSAVQASLSLPATPVGKGTE 226



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 25/113 (22%), Positives = 59/113 (52%), Gaps = 22/113 (19%)

Query: 19  DQIIEYLK--QQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVK 76
           D+++E+ +  +++    E  ++QA  R  + L+ +N +LK E+E LK++L + +     K
Sbjct: 35  DELVEFQEGSRELEAELEAQLVQAEQRN-RDLQADNQRLKYEVEALKEKL-EHQYAQSYK 92

Query: 77  QIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK 129
           Q+           S++ +++ Q+ A+       KEQ+     + ++A + +E+
Sbjct: 93  QV-----------SVLEDDLSQTRAI-------KEQLHKYVRELEQANDDLER 127



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 34/168 (20%), Positives = 68/168 (40%), Gaps = 22/168 (13%)

Query: 2   ANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEK------------AILQATLREEKKLR 49
           A  +A L + EQ+  +     + LK +V  LKEK            ++L+  L + + ++
Sbjct: 49  AELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIK 108

Query: 50  VENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGT 109
            +  K  +E+E+   +L +A+    V    F        N  +  N    + +       
Sbjct: 109 EQLHKYVRELEQANDDLERAKRATIVSLEDFEQ----RLNQAIERNAFLESEL-----DE 159

Query: 110 KEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKP-IDVSRLD 156
           KE +       K     + ++   +E++Q+    SA S P +D  ++D
Sbjct: 160 KESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMD 207


>gi|71284108 nudE nuclear distribution gene E homolog (A.
           nidulans)-like 1 isoform A [Homo sapiens]
          Length = 328

 Score = 36.2 bits (82), Expect = 0.038
 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 1/80 (1%)

Query: 32  LKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSM 91
           ++  A L++ L E++ L V   +LK E  +L+QEL   E Q  V +   PS   L    M
Sbjct: 147 IERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKM 206

Query: 92  VSE-NVIQSTAVTTVSSGTK 110
            S      S   T V  GT+
Sbjct: 207 DSAVQASLSLPATPVGKGTE 226



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 25/113 (22%), Positives = 59/113 (52%), Gaps = 22/113 (19%)

Query: 19  DQIIEYLK--QQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVK 76
           D+++E+ +  +++    E  ++QA  R  + L+ +N +LK E+E LK++L + +     K
Sbjct: 35  DELVEFQEGSRELEAELEAQLVQAEQRN-RDLQADNQRLKYEVEALKEKL-EHQYAQSYK 92

Query: 77  QIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEK 129
           Q+           S++ +++ Q+ A+       KEQ+     + ++A + +E+
Sbjct: 93  QV-----------SVLEDDLSQTRAI-------KEQLHKYVRELEQANDDLER 127



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 34/168 (20%), Positives = 68/168 (40%), Gaps = 22/168 (13%)

Query: 2   ANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEK------------AILQATLREEKKLR 49
           A  +A L + EQ+  +     + LK +V  LKEK            ++L+  L + + ++
Sbjct: 49  AELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIK 108

Query: 50  VENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGT 109
            +  K  +E+E+   +L +A+    V    F        N  +  N    + +       
Sbjct: 109 EQLHKYVRELEQANDDLERAKRATIVSLEDFEQ----RLNQAIERNAFLESEL-----DE 159

Query: 110 KEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKP-IDVSRLD 156
           KE +       K     + ++   +E++Q+    SA S P +D  ++D
Sbjct: 160 KESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMD 207


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 36.2 bits (82), Expect = 0.038
 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 5/69 (7%)

Query: 2   ANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEE 61
           +N D  L  LE+  +E ++IIE LK+Q      +   +  L E +  R EN  LK+++  
Sbjct: 577 SNTDTALATLEEALSEKERIIERLKEQ-----RERDDRERLEEIESFRKENKDLKEKVNA 631

Query: 62  LKQELIQAE 70
           L+ EL + E
Sbjct: 632 LQAELTEKE 640



 Score = 35.4 bits (80), Expect = 0.066
 Identities = 38/148 (25%), Positives = 66/148 (44%), Gaps = 12/148 (8%)

Query: 7   VLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAK-----LKKEIEE 61
           V++  + K A  ++ I  L+ ++ +LK   +L    REE+  ++E  K     +K +I++
Sbjct: 379 VIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQ 438

Query: 62  LKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEK 121
           LKQEL + E +    Q      T L   S  + +  Q   V   S   KEQ       E 
Sbjct: 439 LKQELSKKESELLALQ------TKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEV 492

Query: 122 KA-KEKIEKKGEKKEKKQQSIAGSADSK 148
            A + ++E+K     KK + +    + K
Sbjct: 493 DALRLRLEEKESFLNKKTKQLQDLTEEK 520



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 40/166 (24%), Positives = 77/166 (46%), Gaps = 19/166 (11%)

Query: 12  EQKGA----EADQIIEYLKQQVSLLKEKAILQATLREEKKL---RVENAKLKKEIEELKQ 64
           EQ+ A    E D +   L+++ S L +K      L EEK      + + K   E++E K 
Sbjct: 482 EQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKI 541

Query: 65  ELIQAEIQNGVKQIPFP----SGTPLHANSMVSENVIQSTAVTTVSS--GTKEQI----- 113
            ++Q +I+N  +Q+       +       S+ +++    TA+ T+      KE+I     
Sbjct: 542 NVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLK 601

Query: 114 KGGTGDEKKAKEKIEK-KGEKKEKKQQSIAGSADSKPIDVSRLDLR 158
           +    D+++  E+IE  + E K+ K++  A  A+    + S +DL+
Sbjct: 602 EQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK 647


>gi|33946313 ninein isoform 4 [Homo sapiens]
          Length = 2096

 Score = 36.2 bits (82), Expect = 0.038
 Identities = 25/98 (25%), Positives = 50/98 (51%), Gaps = 2/98 (2%)

Query: 43   REEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAV 102
            ++ + ++ ENA ++K +E LK+++ + +I+N  +Q+   +      NS   E + +    
Sbjct: 1562 QKTETVKQENAAVQKMVENLKKQISELKIKN--QQLDLENTELSQKNSQNQEKLQELNQR 1619

Query: 103  TTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQS 140
             T     KE+  G +  E++ +EK   K E +  K QS
Sbjct: 1620 LTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQS 1657


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,193,143
Number of Sequences: 37866
Number of extensions: 598236
Number of successful extensions: 5063
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 289
Number of HSP's that attempted gapping in prelim test: 4196
Number of HSP's gapped (non-prelim): 1147
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.