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Search of human proteins with 42544243
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42544243 dynamin 3 isoform a [Homo sapiens]
(863 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42544243 dynamin 3 isoform a [Homo sapiens] 1717 0.0
gi|209915561 dynamin 3 isoform b [Homo sapiens] 1702 0.0
gi|56549119 dynamin 2 isoform 3 [Homo sapiens] 1377 0.0
gi|56549125 dynamin 2 isoform 4 [Homo sapiens] 1373 0.0
gi|56549121 dynamin 2 isoform 1 [Homo sapiens] 1372 0.0
gi|56549123 dynamin 2 isoform 2 [Homo sapiens] 1367 0.0
gi|59853099 dynamin 1 isoform 1 [Homo sapiens] 1358 0.0
gi|56549117 dynamin 1 isoform 2 [Homo sapiens] 1345 0.0
gi|171460918 dynamin 1-like isoform 3 [Homo sapiens] 438 e-122
gi|171460914 dynamin 1-like isoform 1 [Homo sapiens] 437 e-122
gi|171460916 dynamin 1-like isoform 2 [Homo sapiens] 437 e-122
gi|222136619 myxovirus resistance protein 1 [Homo sapiens] 230 4e-60
gi|222136617 myxovirus resistance protein 1 [Homo sapiens] 230 4e-60
gi|11342664 myxovirus resistance protein 2 [Homo sapiens] 219 9e-57
gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens] 117 5e-26
gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens] 117 5e-26
gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens] 117 5e-26
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] 103 7e-22
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] 103 7e-22
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] 103 7e-22
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] 103 7e-22
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] 103 7e-22
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] 103 7e-22
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens] 103 7e-22
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens] 103 7e-22
gi|113425405 PREDICTED: similar to dynamin 1 [Homo sapiens] 92 2e-18
gi|239745270 PREDICTED: hypothetical protein XP_002343416 [Homo ... 86 1e-16
gi|239745262 PREDICTED: hypothetical protein XP_002343372 [Homo ... 86 1e-16
gi|239745286 PREDICTED: hypothetical protein XP_002343417 [Homo ... 86 2e-16
gi|153792074 proline rich 12 [Homo sapiens] 62 2e-09
>gi|42544243 dynamin 3 isoform a [Homo sapiens]
Length = 863
Score = 1717 bits (4446), Expect = 0.0
Identities = 863/863 (100%), Positives = 863/863 (100%)
Query: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI
Sbjct: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL
Sbjct: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID
Sbjct: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV
Sbjct: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
Query: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE
Sbjct: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
Query: 601 LACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETIRNLV 660
LACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETIRNLV
Sbjct: 601 LACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETIRNLV 660
Query: 661 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 720
DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD
Sbjct: 661 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 720
Query: 721 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPL 780
EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPL
Sbjct: 721 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPL 780
Query: 781 ARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP 840
ARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP
Sbjct: 781 ARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP 840
Query: 841 SRRPPPSPTRPTIIRPLESSLLD 863
SRRPPPSPTRPTIIRPLESSLLD
Sbjct: 841 SRRPPPSPTRPTIIRPLESSLLD 863
>gi|209915561 dynamin 3 isoform b [Homo sapiens]
Length = 859
Score = 1702 bits (4408), Expect = 0.0
Identities = 859/863 (99%), Positives = 859/863 (99%), Gaps = 4/863 (0%)
Query: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI
Sbjct: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL
Sbjct: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID
Sbjct: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV
Sbjct: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
Query: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE
Sbjct: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
Query: 601 LACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETIRNLV 660
LACDSQEDVDSWKASLLRAGVYPDKSV AENDENGQAENFSMDPQLERQVETIRNLV
Sbjct: 601 LACDSQEDVDSWKASLLRAGVYPDKSV----AENDENGQAENFSMDPQLERQVETIRNLV 656
Query: 661 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 720
DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD
Sbjct: 657 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 716
Query: 721 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPL 780
EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPL
Sbjct: 717 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPL 776
Query: 781 ARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP 840
ARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP
Sbjct: 777 ARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP 836
Query: 841 SRRPPPSPTRPTIIRPLESSLLD 863
SRRPPPSPTRPTIIRPLESSLLD
Sbjct: 837 SRRPPPSPTRPTIIRPLESSLLD 859
>gi|56549119 dynamin 2 isoform 3 [Homo sapiens]
Length = 866
Score = 1377 bits (3565), Expect = 0.0
Identities = 697/874 (79%), Positives = 774/874 (88%), Gaps = 19/874 (2%)
Query: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP R+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
+INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPD+AFEAIVKKQ+VKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL 420
Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
K P LK VDLVIQELINTV++CT KL+++PRL EETERIV +IREREG+TKDQ+LLLID
Sbjct: 421 KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
I+ SYINTNHEDFIGFANAQQRS+Q++KK + NQVIR+GWLTI+NI +MKGGSK YWFV
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
Query: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
LTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD R +E
Sbjct: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
Query: 601 LACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETIRNLV 660
LACDSQEDVDSWKAS LRAGVYP+K ++AEN++ Q FSMDPQLERQVETIRNLV
Sbjct: 601 LACDSQEDVDSWKASFLRAGVYPEK----DQAENEDGAQENTFSMDPQLERQVETIRNLV 656
Query: 661 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 720
DSY++IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QAQRRD
Sbjct: 657 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 716
Query: 721 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSA-P 779
+MLRMY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q + SPT QRRP S P
Sbjct: 717 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVSSIHP 773
Query: 780 LARPTSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPT 833
RP + RGP P IP P APP+P RPGP F ++SD F APPQ+PSRP
Sbjct: 774 PGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIPSRPV 832
Query: 834 R----APPSVPSRRPPPSPTRPTIIRPLESSLLD 863
R PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 833 RIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866
>gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
Length = 866
Score = 1373 bits (3554), Expect = 0.0
Identities = 695/874 (79%), Positives = 771/874 (88%), Gaps = 19/874 (2%)
Query: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP R+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
+INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
K PSLK VDLV+ EL +KKC +KL+++PRL EETERIV +IREREG+TKDQ+LLLID
Sbjct: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV 540
I+ SYINTNHEDFIGFANAQQRS+Q++KK + NQVIR+GWLTI+NI +MKGGSK YWFV
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQVIRRGWLTINNISLMKGGSKEYWFV 540
Query: 541 LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE 600
LTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD R +E
Sbjct: 541 LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE 600
Query: 601 LACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETIRNLV 660
LACDSQEDVDSWKAS LRAGVYP+K ++AEN++ Q FSMDPQLERQVETIRNLV
Sbjct: 601 LACDSQEDVDSWKASFLRAGVYPEK----DQAENEDGAQENTFSMDPQLERQVETIRNLV 656
Query: 661 DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD 720
DSY++IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QAQRRD
Sbjct: 657 DSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQAQRRD 716
Query: 721 EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSA-P 779
+MLRMY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q + SPT QRRP S P
Sbjct: 717 DMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVSSIHP 773
Query: 780 LARPTSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPT 833
RP + RGP P IP P APP+P RPGP F ++SD F APPQ+PSRP
Sbjct: 774 PGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIPSRPV 832
Query: 834 R----APPSVPSRRPPPSPTRPTIIRPLESSLLD 863
R PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 833 RIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 866
>gi|56549121 dynamin 2 isoform 1 [Homo sapiens]
Length = 870
Score = 1372 bits (3550), Expect = 0.0
Identities = 697/878 (79%), Positives = 774/878 (88%), Gaps = 23/878 (2%)
Query: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP R+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
+INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPD+AFEAIVKKQ+VKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL 420
Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
K P LK VDLVIQELINTV++CT KL+++PRL EETERIV +IREREG+TKDQ+LLLID
Sbjct: 421 KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQ----VIRKGWLTISNIGIMKGGSKG 536
I+ SYINTNHEDFIGFANAQQRS+Q++KK + NQ VIR+GWLTI+NI +MKGGSK
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE 540
Query: 537 YWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDY 596
YWFVLTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD
Sbjct: 541 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 600
Query: 597 RFLELACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETI 656
R +ELACDSQEDVDSWKAS LRAGVYP+K ++AEN++ Q FSMDPQLERQVETI
Sbjct: 601 RQIELACDSQEDVDSWKASFLRAGVYPEK----DQAENEDGAQENTFSMDPQLERQVETI 656
Query: 657 RNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQA 716
RNLVDSY++IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QA
Sbjct: 657 RNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQA 716
Query: 717 QRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTL 776
QRRD+MLRMY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q + SPT QRRP
Sbjct: 717 QRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVS 773
Query: 777 SA-PLARPTSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVP 829
S P RP + RGP P IP P APP+P RPGP F ++SD F APPQ+P
Sbjct: 774 SIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIP 832
Query: 830 SRPTR----APPSVPSRRPPPSPTRPTIIRPLESSLLD 863
SRP R PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 833 SRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 870
>gi|56549123 dynamin 2 isoform 2 [Homo sapiens]
Length = 870
Score = 1367 bits (3539), Expect = 0.0
Identities = 695/878 (79%), Positives = 771/878 (87%), Gaps = 23/878 (2%)
Query: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNR MEELIPLVN+LQDAFS++GQSC L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
SGIVTRRPL+LQL+ SK E+AEFLHCK KKFTDFDEVR EIEAETDRVTG NKGIS +PI
Sbjct: 61 SGIVTRRPLILQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQI++MI+QFI+RE+ LILAVTPAN D
Sbjct: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
DI+GKKDI+AA+ AERKFFLSHPAYRH+ADRMGTPHLQK LNQQLTNHIR++LP R+KL
Sbjct: 241 DIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPALRSKL 300
Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
Q QLLS+E EVE YKNF+P+DPTRKTKALLQMVQQF VDFEKRIEGSGDQVDTLELSGGA
Sbjct: 301 QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA 360
Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
+INRIFHERFPFE+VKMEF+EK+LRREISYAIKNIHG+RTGLFTPDMAFEAIVKKQIVKL
Sbjct: 361 RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDMAFEAIVKKQIVKL 420
Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
K PSLK VDLV+ EL +KKC +KL+++PRL EETERIV +IREREG+TKDQ+LLLID
Sbjct: 421 KEPSLKCVDLVVSELATVIKKCAEKLSSYPRLREETERIVTTYIREREGRTKDQILLLID 480
Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQ----VIRKGWLTISNIGIMKGGSKG 536
I+ SYINTNHEDFIGFANAQQRS+Q++KK + NQ VIR+GWLTI+NI +MKGGSK
Sbjct: 481 IEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKE 540
Query: 537 YWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDY 596
YWFVLTAESLSWYKD+EEKEKKYMLPLDNLK+RDVEK FMS+KH+FA+FNTEQRNVYKD
Sbjct: 541 YWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDL 600
Query: 597 RFLELACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETI 656
R +ELACDSQEDVDSWKAS LRAGVYP+K ++AEN++ Q FSMDPQLERQVETI
Sbjct: 601 RQIELACDSQEDVDSWKASFLRAGVYPEK----DQAENEDGAQENTFSMDPQLERQVETI 656
Query: 657 RNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQA 716
RNLVDSY++IINK IRDL+PKTIMHLMINN K FI+ ELLA LYSS DQ++LMEESA+QA
Sbjct: 657 RNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESADQA 716
Query: 717 QRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTL 776
QRRD+MLRMY ALKEAL IIGDIST+TVSTP PPPVDD+W+Q + SPT QRRP
Sbjct: 717 QRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSH---SPTPQRRPVS 773
Query: 777 SA-PLARPTSGRGPAPA---IPSP---GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVP 829
S P RP + RGP P IP P APP+P RPGP F ++SD F APPQ+P
Sbjct: 774 SIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVF-ANSDLFPAPPQIP 832
Query: 830 SRPTR----APPSVPSRRPPPSPTRPTIIRPLESSLLD 863
SRP R PP VPSRRPP +P+RPTIIRP E SLLD
Sbjct: 833 SRPVRIPPGIPPGVPSRRPPAAPSRPTIIRPAEPSLLD 870
>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
Length = 864
Score = 1358 bits (3515), Expect = 0.0
Identities = 692/868 (79%), Positives = 760/868 (87%), Gaps = 20/868 (2%)
Query: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNR ME+LIPLVNRLQDAFSA+GQ+ L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
SGIVTRRPLVLQLV + EYAEFLHCKGKKFTDF+EVRLEIEAETDRVTG NKGIS +PI
Sbjct: 61 SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QIR+M+MQF+T+ENCLILAV+PAN+D
Sbjct: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
DIDGKKDI AA+ AERKFFLSHP+YRH+ADRMGTP+LQKVLNQQLTNHIRDTLP RNKL
Sbjct: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
Q QLLSIE EVE YKNF+P+DP RKTKALLQMVQQFAVDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
+INRIFHERFPFE+VKMEF+EKELRREISYAIKNIHGIRTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
+ P LK VD+VI ELI+TV++CTKKL +PRL EE ERIV HIREREG+TK+QV+LLID
Sbjct: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQ----VIRKGWLTISNIGIMKGGSKG 536
I+++Y+NTNHEDFIGFANAQQRS+Q++KK T GNQ VIRKGWLTI+NIGIMKGGSK
Sbjct: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
Query: 537 YWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDY 596
YWFVLTAE+LSWYKDDEEKEKKYML +DNLK+RDVEK FMSSKHIFALFNTEQRNVYKDY
Sbjct: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
Query: 597 RFLELACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENF--SMDPQLERQVE 654
R LELAC++QE+VDSWKAS LRAGVYP++ KA E +++F SMDPQLERQVE
Sbjct: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
Query: 655 TIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAE 714
TIRNLVDSYM+I+NK +RDL+PKTIMHLMINN K+FI SELLA LYS DQNTLMEESAE
Sbjct: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
Query: 715 QAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQ-----HSRRSPPPSPT 769
QAQRRDEMLRMY ALKEAL IIGDI+T TVSTP PPPVDDSW+Q RRSP SPT
Sbjct: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
Query: 770 TQRRPTLSAPLARPTSGRGPAPAIPSPGPH-SGAPPVPFRPGPLPPFPSSSDSFGAPPQV 828
QRR + P ARP S RGPAP P G GAPPVP RPG +S D FG PPQV
Sbjct: 781 PQRRAP-AVPPARPGS-RGPAPGPPPAGSALGGAPPVPSRPG------ASPDPFGPPPQV 832
Query: 829 PSRPTRAPPSVPSRRPPPSPTRPTIIRP 856
PSRP RAPP VPSR SP+RP RP
Sbjct: 833 PSRPNRAPPGVPSRSGQASPSRPESPRP 860
>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
Length = 851
Score = 1345 bits (3481), Expect = 0.0
Identities = 684/852 (80%), Positives = 751/852 (88%), Gaps = 20/852 (2%)
Query: 1 MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
MGNR ME+LIPLVNRLQDAFSA+GQ+ L+LPQIAVVGGQSAGKSSVLENFVGRDFLPRG
Sbjct: 1 MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG 60
Query: 61 SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI 120
SGIVTRRPLVLQLV + EYAEFLHCKGKKFTDF+EVRLEIEAETDRVTG NKGIS +PI
Sbjct: 61 SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI 120
Query: 121 NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD 180
NLRVYSPHVLNLTL+DLPG+TKVPVGDQPPDIE+QIR+M+MQF+T+ENCLILAV+PAN+D
Sbjct: 121 NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD 180
Query: 181 LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK 240
LANSDALK+AKEVDPQG RTIGVITKLDLMDEGTDARDVLENKLLPLRRGY+GVVNRSQK
Sbjct: 181 LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK 240
Query: 241 DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL 300
DIDGKKDI AA+ AERKFFLSHP+YRH+ADRMGTP+LQKVLNQQLTNHIRDTLP RNKL
Sbjct: 241 DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL 300
Query: 301 QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA 360
Q QLLSIE EVE YKNF+P+DP RKTKALLQMVQQFAVDFEKRIEGSGDQ+DT ELSGGA
Sbjct: 301 QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA 360
Query: 361 KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL 420
+INRIFHERFPFE+VKMEF+EKELRREISYAIKNIHGIRTGLFTPDMAFE IVKKQ+ K+
Sbjct: 361 RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI 420
Query: 421 KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID 480
+ P LK VD+VI ELI+TV++CTKKL +PRL EE ERIV HIREREG+TK+QV+LLID
Sbjct: 421 REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID 480
Query: 481 IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQ----VIRKGWLTISNIGIMKGGSKG 536
I+++Y+NTNHEDFIGFANAQQRS+Q++KK T GNQ VIRKGWLTI+NIGIMKGGSK
Sbjct: 481 IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE 540
Query: 537 YWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDY 596
YWFVLTAE+LSWYKDDEEKEKKYML +DNLK+RDVEK FMSSKHIFALFNTEQRNVYKDY
Sbjct: 541 YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY 600
Query: 597 RFLELACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENF--SMDPQLERQVE 654
R LELAC++QE+VDSWKAS LRAGVYP++ KA E +++F SMDPQLERQVE
Sbjct: 601 RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE 660
Query: 655 TIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAE 714
TIRNLVDSYM+I+NK +RDL+PKTIMHLMINN K+FI SELLA LYS DQNTLMEESAE
Sbjct: 661 TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE 720
Query: 715 QAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQ-----HSRRSPPPSPT 769
QAQRRDEMLRMY ALKEAL IIGDI+T TVSTP PPPVDDSW+Q RRSP SPT
Sbjct: 721 QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT 780
Query: 770 TQRRPTLSAPLARPTSGRGPAPAIPSPGPH-SGAPPVPFRPGPLPPFPSSSDSFGAPPQV 828
QRR + P ARP S RGPAP P G GAPPVP RPG +S D FG PPQV
Sbjct: 781 PQRRAP-AVPPARPGS-RGPAPGPPPAGSALGGAPPVPSRPG------ASPDPFGPPPQV 832
Query: 829 PSRPTRAPPSVP 840
PSRP RAPP VP
Sbjct: 833 PSRPNRAPPGVP 844
>gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]
Length = 699
Score = 438 bits (1126), Expect = e-122
Identities = 243/548 (44%), Positives = 356/548 (64%), Gaps = 31/548 (5%)
Query: 6 MEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
ME LIP++N+LQD F+ +G +++LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1 MEALIPVINKLQDVFNTVGAD-IIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
Query: 66 RRPLVLQLV----------------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVT 109
RRPL+LQLV E+ +FLH K K +TDFDE+R EIE ET+R++
Sbjct: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
Query: 110 GMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENC 169
G NKG+S PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QIRE+I++FI+ N
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
Query: 170 LILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
+ILAVT ANTD+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
Query: 230 GYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHI 289
G +GVVNRSQ DI+ KK + ++ E F Y +A+R GT +L + LN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
Query: 290 RDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGD 349
RD LP + ++ +L+ +++ +P D K+ LLQ++ +FA ++ IEG+
Sbjct: 298 RDCLPELKTRI--NVLAAQYQSLLNSYGEPVDD--KSATLLQLITKFATEYCNTIEGTAK 353
Query: 350 QVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAF 409
++T EL GGA+I IFHE F + ++ +I AI+N G R LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
Query: 410 EAIVKKQIVKLKGPSLKSVDLVIQELINTVKKC----TKKLANFPRLCEETERIVANHIR 465
E +VK+QI +L+ PSL+ V+LV +E+ ++ C T++L FP+L + +V +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
Query: 466 EREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTIS 525
+R T + V L+ I+++YINT H DF + + ++ N++ R+ +S
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRR----NRLARELPSAVS 529
Query: 526 NIGIMKGG 533
+ GG
Sbjct: 530 RDKVASGG 537
Score = 79.3 bits (194), Expect = 1e-14
Identities = 40/90 (44%), Positives = 57/90 (63%)
Query: 650 ERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLM 709
+R E I L+ SY I+ K I+D +PK +MH ++N+VKD + SEL+ QLY S + L+
Sbjct: 604 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 663
Query: 710 EESAEQAQRRDEMLRMYQALKEALGIIGDI 739
ES + AQRR E M +AL+ A II +I
Sbjct: 664 TESEDMAQRRKEAADMLKALQGASQIIAEI 693
>gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]
Length = 736
Score = 437 bits (1125), Expect = e-122
Identities = 238/531 (44%), Positives = 349/531 (65%), Gaps = 27/531 (5%)
Query: 6 MEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
ME LIP++N+LQD F+ +G +++LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1 MEALIPVINKLQDVFNTVGAD-IIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
Query: 66 RRPLVLQLV----------------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVT 109
RRPL+LQLV E+ +FLH K K +TDFDE+R EIE ET+R++
Sbjct: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
Query: 110 GMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENC 169
G NKG+S PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QIRE+I++FI+ N
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
Query: 170 LILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
+ILAVT ANTD+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
Query: 230 GYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHI 289
G +GVVNRSQ DI+ KK + ++ E F Y +A+R GT +L + LN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
Query: 290 RDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGD 349
RD LP + ++ +L+ +++ +P D K+ LLQ++ +FA ++ IEG+
Sbjct: 298 RDCLPELKTRI--NVLAAQYQSLLNSYGEPVDD--KSATLLQLITKFATEYCNTIEGTAK 353
Query: 350 QVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAF 409
++T EL GGA+I IFHE F + ++ +I AI+N G R LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
Query: 410 EAIVKKQIVKLKGPSLKSVDLVIQELINTVKKC----TKKLANFPRLCEETERIVANHIR 465
E +VK+QI +L+ PSL+ V+LV +E+ ++ C T++L FP+L + +V +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
Query: 466 EREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQV 516
+R T + V L+ I+++YINT H DF + + ++ + ++
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLAREL 524
Score = 79.3 bits (194), Expect = 1e-14
Identities = 40/90 (44%), Positives = 57/90 (63%)
Query: 650 ERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLM 709
+R E I L+ SY I+ K I+D +PK +MH ++N+VKD + SEL+ QLY S + L+
Sbjct: 641 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 700
Query: 710 EESAEQAQRRDEMLRMYQALKEALGIIGDI 739
ES + AQRR E M +AL+ A II +I
Sbjct: 701 TESEDMAQRRKEAADMLKALQGASQIIAEI 730
>gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]
Length = 710
Score = 437 bits (1125), Expect = e-122
Identities = 238/531 (44%), Positives = 349/531 (65%), Gaps = 27/531 (5%)
Query: 6 MEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVT 65
ME LIP++N+LQD F+ +G +++LPQI VVG QS+GKSSVLE+ VGRD LPRG+GIVT
Sbjct: 1 MEALIPVINKLQDVFNTVGAD-IIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVT 59
Query: 66 RRPLVLQLV----------------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVT 109
RRPL+LQLV E+ +FLH K K +TDFDE+R EIE ET+R++
Sbjct: 60 RRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERIS 119
Query: 110 GMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENC 169
G NKG+S PI+L+++SP+V+NLTL+DLPG+TKVPVGDQP DIE QIRE+I++FI+ N
Sbjct: 120 GNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNS 179
Query: 170 LILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRR 229
+ILAVT ANTD+A S+ALK+++EVDP G RT+ VITKLDLMD GTDA DVL +++P++
Sbjct: 180 IILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKL 239
Query: 230 GYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHI 289
G +GVVNRSQ DI+ KK + ++ E F Y +A+R GT +L + LN+ L +HI
Sbjct: 240 GIIGVVNRSQLDINNKKSVTDSIRDEYAFL--QKKYPSLANRNGTKYLARTLNRLLMHHI 297
Query: 290 RDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGD 349
RD LP + ++ +L+ +++ +P D K+ LLQ++ +FA ++ IEG+
Sbjct: 298 RDCLPELKTRI--NVLAAQYQSLLNSYGEPVDD--KSATLLQLITKFATEYCNTIEGTAK 353
Query: 350 QVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAF 409
++T EL GGA+I IFHE F + ++ +I AI+N G R LF P+++F
Sbjct: 354 YIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSF 413
Query: 410 EAIVKKQIVKLKGPSLKSVDLVIQELINTVKKC----TKKLANFPRLCEETERIVANHIR 465
E +VK+QI +L+ PSL+ V+LV +E+ ++ C T++L FP+L + +V +R
Sbjct: 414 ELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLR 473
Query: 466 EREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQV 516
+R T + V L+ I+++YINT H DF + + ++ + ++
Sbjct: 474 KRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLAREL 524
Score = 79.3 bits (194), Expect = 1e-14
Identities = 40/90 (44%), Positives = 57/90 (63%)
Query: 650 ERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLM 709
+R E I L+ SY I+ K I+D +PK +MH ++N+VKD + SEL+ QLY S + L+
Sbjct: 615 QRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLL 674
Query: 710 EESAEQAQRRDEMLRMYQALKEALGIIGDI 739
ES + AQRR E M +AL+ A II +I
Sbjct: 675 TESEDMAQRRKEAADMLKALQGASQIIAEI 704
>gi|222136619 myxovirus resistance protein 1 [Homo sapiens]
Length = 662
Score = 230 bits (587), Expect = 4e-60
Identities = 161/439 (36%), Positives = 240/439 (54%), Gaps = 23/439 (5%)
Query: 7 EELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTR 66
E++ P ++ L D+ ALG L LP IAV+G QS+GKSSVLE G LPRGSGIVTR
Sbjct: 47 EKVRPCID-LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSG-VALPRGSGIVTR 104
Query: 67 RPLVLQLV--------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSI 118
PLVL+L K Y ++ + +D EV EI + + G GIS
Sbjct: 105 CPLVLKLKKLVNEDKWRGKVSYQDY----EIEISDASEVEKEINKAQNAIAGEGMGISHE 160
Query: 119 PINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPAN 178
I L + S V +LTLIDLPGIT+V VG+QP DI Y+I+ +I ++I R+ + L V P+N
Sbjct: 161 LITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSN 220
Query: 179 TDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDAR--DVLENKLLPLRRGYVGVVN 236
D+A ++AL +A+EVDP+G RTIG++TK DL+D+GT+ + DV+ N + L++GY+ V
Sbjct: 221 VDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKC 280
Query: 237 RSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIAD--RMGTPHLQKVLNQQLTNHIRDTLP 294
R Q++I + + A+ E+ FF +HP +R + + + P L + L +L HI +LP
Sbjct: 281 RGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLP 340
Query: 295 NFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTL 354
N+++ I E++ Y PED K L+ V F D ++G + V
Sbjct: 341 LLENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEE 399
Query: 355 ELSGGAKINRIFHERFPFEIVKMEFNE--KELRREISYAIKNIHGIRTGLFTPDMAFEAI 412
++ ++ FH+ I++ F E K L R+I G F FE I
Sbjct: 400 DIRLFTRLRHEFHKW--STIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETI 457
Query: 413 VKKQIVKLKGPSLKSVDLV 431
VK+QI L+ P++ + V
Sbjct: 458 VKQQIKALEEPAVDMLHTV 476
>gi|222136617 myxovirus resistance protein 1 [Homo sapiens]
Length = 662
Score = 230 bits (587), Expect = 4e-60
Identities = 161/439 (36%), Positives = 240/439 (54%), Gaps = 23/439 (5%)
Query: 7 EELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTR 66
E++ P ++ L D+ ALG L LP IAV+G QS+GKSSVLE G LPRGSGIVTR
Sbjct: 47 EKVRPCID-LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSG-VALPRGSGIVTR 104
Query: 67 RPLVLQLV--------TSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSI 118
PLVL+L K Y ++ + +D EV EI + + G GIS
Sbjct: 105 CPLVLKLKKLVNEDKWRGKVSYQDY----EIEISDASEVEKEINKAQNAIAGEGMGISHE 160
Query: 119 PINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPAN 178
I L + S V +LTLIDLPGIT+V VG+QP DI Y+I+ +I ++I R+ + L V P+N
Sbjct: 161 LITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSN 220
Query: 179 TDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDAR--DVLENKLLPLRRGYVGVVN 236
D+A ++AL +A+EVDP+G RTIG++TK DL+D+GT+ + DV+ N + L++GY+ V
Sbjct: 221 VDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKC 280
Query: 237 RSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIAD--RMGTPHLQKVLNQQLTNHIRDTLP 294
R Q++I + + A+ E+ FF +HP +R + + + P L + L +L HI +LP
Sbjct: 281 RGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLP 340
Query: 295 NFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTL 354
N+++ I E++ Y PED K L+ V F D ++G + V
Sbjct: 341 LLENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGE-ETVGEE 399
Query: 355 ELSGGAKINRIFHERFPFEIVKMEFNE--KELRREISYAIKNIHGIRTGLFTPDMAFEAI 412
++ ++ FH+ I++ F E K L R+I G F FE I
Sbjct: 400 DIRLFTRLRHEFHKW--STIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETI 457
Query: 413 VKKQIVKLKGPSLKSVDLV 431
VK+QI L+ P++ + V
Sbjct: 458 VKQQIKALEEPAVDMLHTV 476
>gi|11342664 myxovirus resistance protein 2 [Homo sapiens]
Length = 715
Score = 219 bits (558), Expect = 9e-57
Identities = 162/465 (34%), Positives = 237/465 (50%), Gaps = 14/465 (3%)
Query: 16 LQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVT 75
L D+ ALG L LP IAV+G QS+GKSSVLE G LPRGSGIVTR PLVL+L
Sbjct: 103 LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVA-LPRGSGIVTRCPLVLKLKK 161
Query: 76 SKAE-YAEFLHCKGKKFT--DFDEVRLEIEAETDRVTGMNKGISSIPINLRVYSPHVLNL 132
E +A + + + D +V EI + + G +GIS I+L + SP V +L
Sbjct: 162 QPCEAWAGRISYRNTELELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDL 221
Query: 133 TLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTDLANSDALKLAKE 192
T+IDLPGIT+V V +QP DI QI+ +I ++I R+ + L V P N D+A ++AL +A E
Sbjct: 222 TIIDLPGITRVAVDNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHE 281
Query: 193 VDPQGLRTIGVITKLDLMDEGTD--ARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKA 250
VDP+G RTIG++TK DLMD GT+ +V+ N PL++GY+ V R Q++I + +
Sbjct: 282 VDPEGDRTIGILTKPDLMDRGTEKSVMNVVRNLTYPLKKGYMIVKCRGQQEITNRLSLAE 341
Query: 251 AMLAERKFFLSHPAYRHIADR--MGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIE 308
A E FF +HP +R + + P L + L +L HI+ +LP +++
Sbjct: 342 ATKKEITFFQTHPYFRVLLEEGSATVPRLAERLTTELIMHIQKSLPLLEGQIRESHQKAT 401
Query: 309 HEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGAKINRIFHE 368
E+ P K L++ ++ F D EK +EG + V E KI F
Sbjct: 402 EELRRCGADIPSQEADKMFFLIEKIKMFNQDIEKLVEGE-EVVRENETRLYNKIREDFKN 460
Query: 369 RFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSL--- 425
+ + + E+ K G F FE IV + I +L P+L
Sbjct: 461 WVGILATNTQKVKNIIHEEVEKYEKQYRGKELLGFVNYKTFEIIVHQYIQQLVEPALSML 520
Query: 426 -KSVDLVIQELINTVKKCTKKLANFPRLCEET-ERIVANHIRERE 468
K+++++ Q IN KK + N + + T E I H + E
Sbjct: 521 QKAMEIIQQAFINVAKKHFGEFFNLNQTVQSTIEDIKVKHTAKAE 565
>gi|239756350 PREDICTED: UPF0621 protein C-like [Homo sapiens]
Length = 135
Score = 117 bits (293), Expect = 5e-26
Identities = 67/119 (56%), Positives = 88/119 (73%), Gaps = 7/119 (5%)
Query: 635 DENGQAENF--SMDPQLERQVETIRNLVDSYMSIINKCIRDLI----PKTIMHLMINNVK 688
+ENG +++F SMDPQL Q+ET ++LVDSY++I+NK + DL+ PKT MHLMINN+
Sbjct: 13 EENG-SDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMINNMH 71
Query: 689 DFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTP 747
+FI SELLA+LYS D+N LME+S EQA+ +E L M+ L+EA IIGDI T VS P
Sbjct: 72 EFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTTMVSMP 130
>gi|239750876 PREDICTED: UPF0621 protein C-like [Homo sapiens]
Length = 135
Score = 117 bits (293), Expect = 5e-26
Identities = 67/119 (56%), Positives = 88/119 (73%), Gaps = 7/119 (5%)
Query: 635 DENGQAENF--SMDPQLERQVETIRNLVDSYMSIINKCIRDLI----PKTIMHLMINNVK 688
+ENG +++F SMDPQL Q+ET ++LVDSY++I+NK + DL+ PKT MHLMINN+
Sbjct: 13 EENG-SDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMINNMH 71
Query: 689 DFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTP 747
+FI SELLA+LYS D+N LME+S EQA+ +E L M+ L+EA IIGDI T VS P
Sbjct: 72 EFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTTMVSMP 130
>gi|169208224 PREDICTED: UPF0621 protein C-like [Homo sapiens]
Length = 155
Score = 117 bits (293), Expect = 5e-26
Identities = 67/119 (56%), Positives = 88/119 (73%), Gaps = 7/119 (5%)
Query: 635 DENGQAENF--SMDPQLERQVETIRNLVDSYMSIINKCIRDLI----PKTIMHLMINNVK 688
+ENG +++F SMDPQL Q+ET ++LVDSY++I+NK + DL+ PKT MHLMINN+
Sbjct: 33 EENG-SDSFMHSMDPQLVWQMETTQSLVDSYVAIVNKTVWDLMVGLTPKTTMHLMINNMH 91
Query: 689 DFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTP 747
+FI SELLA+LYS D+N LME+S EQA+ +E L M+ L+EA IIGDI T VS P
Sbjct: 92 EFIFSELLAKLYSCGDENMLMEDSTEQAKWCNETLCMHHVLREAPNIIGDIKTTMVSMP 150
>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
Length = 1015
Score = 103 bits (257), Expect = 7e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 317 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 376
Query: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 377 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 436
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 437 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 496
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 497 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 556
Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 557 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 613
Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
++ + + ++E E +KN P
Sbjct: 614 SVEQQADSFKATRFNLETE---WKNNYP 638
>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
Length = 997
Score = 103 bits (257), Expect = 7e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 299 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 358
Query: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 359 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 418
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 419 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 478
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 479 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 538
Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 539 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 595
Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
++ + + ++E E +KN P
Sbjct: 596 SVEQQADSFKATRFNLETE---WKNNYP 620
>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
Length = 979
Score = 103 bits (257), Expect = 7e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
Query: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 521 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 577
Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
++ + + ++E E +KN P
Sbjct: 578 SVEQQADSFKATRFNLETE---WKNNYP 602
>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
Length = 978
Score = 103 bits (257), Expect = 7e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339
Query: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519
Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 520 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 576
Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
++ + + ++E E +KN P
Sbjct: 577 SVEQQADSFKATRFNLETE---WKNNYP 601
>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
Length = 961
Score = 103 bits (257), Expect = 7e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
Query: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 503 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 559
Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
++ + + ++E E +KN P
Sbjct: 560 SVEQQADSFKATRFNLETE---WKNNYP 584
>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
Length = 942
Score = 103 bits (257), Expect = 7e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 244 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 303
Query: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 304 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 363
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 364 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 423
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 424 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 483
Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 484 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 540
Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
++ + + ++E E +KN P
Sbjct: 541 SVEQQADSFKATRFNLETE---WKNNYP 565
>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
Length = 924
Score = 103 bits (257), Expect = 7e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 226 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 285
Query: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 286 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 345
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 346 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 405
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 406 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 465
Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 466 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 522
Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
++ + + ++E E +KN P
Sbjct: 523 SVEQQADSFKATRFNLETE---WKNNYP 547
>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
Length = 960
Score = 103 bits (257), Expect = 7e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 262 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 321
Query: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 322 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 381
Query: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 382 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 441
Query: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 442 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 501
Query: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 502 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 558
Query: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
++ + + ++E E +KN P
Sbjct: 559 SVEQQADSFKATRFNLETE---WKNNYP 583
>gi|113425405 PREDICTED: similar to dynamin 1 [Homo sapiens]
Length = 105
Score = 92.0 bits (227), Expect = 2e-18
Identities = 52/103 (50%), Positives = 65/103 (63%), Gaps = 3/103 (2%)
Query: 699 LYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQ 758
+YS +QNTLMEE AEQAQ+ DEML M+ ALKEAL IIGDI+ TV+ P PPPVDD+W+Q
Sbjct: 1 MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWLQ 60
Query: 759 HSRRSPPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSG 801
+S P + QR P +AP + + A PH G
Sbjct: 61 --VQSIPDAHRYQRLPP-TAPKSPTRDAQRSALGASGTPPHRG 100
>gi|239745270 PREDICTED: hypothetical protein XP_002343416 [Homo
sapiens]
Length = 63
Score = 85.9 bits (211), Expect = 1e-16
Identities = 40/59 (67%), Positives = 48/59 (81%)
Query: 699 LYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWI 757
+YS +QNTLMEE AEQAQ+ DEML M+ ALKEAL IIGDI+ TV+ P PPPVDD+W+
Sbjct: 1 MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWL 59
>gi|239745262 PREDICTED: hypothetical protein XP_002343372 [Homo
sapiens]
Length = 63
Score = 85.9 bits (211), Expect = 1e-16
Identities = 40/59 (67%), Positives = 48/59 (81%)
Query: 699 LYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWI 757
+YS +QNTLMEE AEQAQ+ DEML M+ ALKEAL IIGDI+ TV+ P PPPVDD+W+
Sbjct: 1 MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVTMPMPPPVDDTWL 59
>gi|239745286 PREDICTED: hypothetical protein XP_002343417 [Homo
sapiens]
Length = 103
Score = 85.5 bits (210), Expect = 2e-16
Identities = 50/99 (50%), Positives = 62/99 (62%), Gaps = 12/99 (12%)
Query: 699 LYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQ 758
+YS +QNTLMEE AEQAQ+ DEML M+ ALKEAL IIGDI+ TV+ PPPVDD+W+Q
Sbjct: 1 MYSCGNQNTLMEELAEQAQQHDEMLHMHHALKEALSIIGDINRTTVT--MPPPVDDTWLQ 58
Query: 759 --------HSRRSPPPSPTTQRRPTLSAPLARPTSGRGP 789
+R PP +P + R + L TSG P
Sbjct: 59 VQSIPDAHRYQRLPPTAPKSPTRDAQRSALG--TSGTPP 95
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 62.0 bits (149), Expect = 2e-09
Identities = 34/98 (34%), Positives = 41/98 (41%), Gaps = 11/98 (11%)
Query: 747 PAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVP 806
P PPP Q PPP P P PL PT P P +P P P P
Sbjct: 1459 PTPPPAPTPQPQPPPPPPPPQPALPSPP----PLVAPTPSSPPPPPLPPPPP-------P 1507
Query: 807 FRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVPSRRP 844
P P PP P ++ APP+ P+ P+ P +P RP
Sbjct: 1508 AMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545
Score = 54.7 bits (130), Expect = 4e-07
Identities = 43/152 (28%), Positives = 62/152 (40%), Gaps = 9/152 (5%)
Query: 710 EESAEQAQRRDEMLRMYQALKEALGIIGDISTA---TVSTPAPPPVDDSWIQHSRRSPPP 766
+E A+ RD + +++ A+ + D A STP PP+ + P
Sbjct: 1383 DEEDSVAKNRD----LQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPG 1438
Query: 767 SPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPP 826
P+ T PL P PA P+P P PP P +P P P + + +PP
Sbjct: 1439 LPSANSNGTPEPPLLEEKPPPTPPPA-PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP 1497
Query: 827 QVPSRPTRAPPSVPSRRPPPSPTRPTIIRPLE 858
P P PP++PS PPP P + P E
Sbjct: 1498 P-PPLPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528
Score = 40.4 bits (93), Expect = 0.007
Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 11/87 (12%)
Query: 772 RRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSR 831
R+P P+ SG+ P S G S PP P P P P + S P Q P
Sbjct: 1664 RKPWHRPPVPVRRSGQAKNPV--SAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPE- 1720
Query: 832 PTRAPPSVPSRRPPPSPTRPTIIRPLE 858
T P PP+P +P+++RP+E
Sbjct: 1721 -TAMP-------EPPAPEKPSLLRPVE 1739
Score = 33.1 bits (74), Expect = 1.1
Identities = 24/85 (28%), Positives = 28/85 (32%), Gaps = 4/85 (4%)
Query: 764 PPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFG 823
PPP PT Q L G +P P P + P P P S+ G
Sbjct: 765 PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSP----SASKVG 820
Query: 824 APPQVPSRPTRAPPSVPSRRPPPSP 848
P+ AP P PPP P
Sbjct: 821 VHLLEPATRDGAPQPPPPPPPPPPP 845
Score = 32.7 bits (73), Expect = 1.5
Identities = 34/123 (27%), Positives = 46/123 (37%), Gaps = 14/123 (11%)
Query: 737 GDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTL----SAPLARPTSGRGPAPA 792
GD P PP D R+ P T P L + P P++
Sbjct: 972 GDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPET---PGLGLDPNKPPELPSTVNAEPLG 1028
Query: 793 IPSPGPHSGAPPVPFRPGPLPPFPSSSDSFG--APPQVPSRPTRAPPS----VPSRRPPP 846
+ GPH APP P P P PP P+S G +P ++P + + + RR PP
Sbjct: 1029 LIQSGPHQAAPPPP-PPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPP 1087
Query: 847 SPT 849
T
Sbjct: 1088 FQT 1090
Score = 32.7 bits (73), Expect = 1.5
Identities = 29/89 (32%), Positives = 35/89 (39%), Gaps = 15/89 (16%)
Query: 774 PTLSAPLARPTSGRGP-APAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRP 832
P L+ P T P APA PGP PP+P P S++S G P P
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGP----PPLPGLP--------SANSNGTPE--PPLL 1453
Query: 833 TRAPPSVPSRRPPPSPTRPTIIRPLESSL 861
PP P P P P P P + +L
Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPPQPAL 1482
Score = 32.0 bits (71), Expect = 2.5
Identities = 31/112 (27%), Positives = 34/112 (30%), Gaps = 34/112 (30%)
Query: 747 PAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSP---------- 796
P PPP PPP P P + L G PA PSP
Sbjct: 833 PQPPP------------PPPPPP----PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP 876
Query: 797 --------GPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP 840
G PP P G PP D GA + T+AP VP
Sbjct: 877 PGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVP 928
Score = 31.6 bits (70), Expect = 3.3
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 799 HSGAPPVPFRPGPLP---PFPSSS--DSFGAPPQVPSRPTRAPPSVPSRRPPPSPTRPTI 853
H+ P F G LP FPSSS ++ P SRP P S+ + PP SP +
Sbjct: 123 HTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGL 182
Query: 854 IRP 856
+ P
Sbjct: 183 LSP 185
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,719,281
Number of Sequences: 37866
Number of extensions: 1947760
Number of successful extensions: 29054
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 428
Number of HSP's successfully gapped in prelim test: 1502
Number of HSP's that attempted gapping in prelim test: 13703
Number of HSP's gapped (non-prelim): 9454
length of query: 863
length of database: 18,247,518
effective HSP length: 111
effective length of query: 752
effective length of database: 14,044,392
effective search space: 10561382784
effective search space used: 10561382784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.