Guide to the Human Genome
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Search of human proteins with 126362983

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|126362983 ribosomal RNA processing 15 homolog [Homo sapiens]
         (282 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|126362983 ribosomal RNA processing 15 homolog [Homo sapiens]       561   e-160
gi|5453567 craniofacial development protein 1 [Homo sapiens]           50   3e-06
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    49   6e-06
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s...    46   3e-05
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]             44   2e-04
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]             44   2e-04
gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa...    43   4e-04
gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s...    43   4e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    41   0.001
gi|55956788 nucleolin [Homo sapiens]                                   40   0.003
gi|155722990 solute carrier family 4 (anion exchanger), member 1...    40   0.003
gi|124517695 ankyrin repeat domain 36B [Homo sapiens]                  40   0.003
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    39   0.004
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    39   0.004
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             39   0.007
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    38   0.009
gi|40807471 transcription termination factor, RNA polymerase II ...    38   0.009
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              38   0.009
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    37   0.015
gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sa...    37   0.015
gi|209915570 amyloid beta A4 protein isoform e precursor [Homo s...    37   0.015
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]      37   0.015
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    37   0.015
gi|4504487 histidine rich calcium binding protein precursor [Hom...    37   0.015
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap...    37   0.015
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi...    37   0.015
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ...    37   0.015
gi|12711676 UPF3 regulator of nonsense transcripts homolog A iso...    37   0.015
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ...    37   0.015
gi|18375525 UPF3 regulator of nonsense transcripts homolog A iso...    37   0.015

>gi|126362983 ribosomal RNA processing 15 homolog [Homo sapiens]
          Length = 282

 Score =  561 bits (1445), Expect = e-160
 Identities = 282/282 (100%), Positives = 282/282 (100%)

Query: 1   MAAAAPDSRVSEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDD 60
           MAAAAPDSRVSEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDD
Sbjct: 1   MAAAAPDSRVSEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDD 60

Query: 61  DAIEADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEK 120
           DAIEADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEK
Sbjct: 61  DAIEADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEK 120

Query: 121 EKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKH 180
           EKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKH
Sbjct: 121 EKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKH 180

Query: 181 QKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTEVKS 240
           QKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTEVKS
Sbjct: 181 QKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTEVKS 240

Query: 241 EEGPGWTILRDDFMMGASMKDWDKESDGPDDSRPESASDSDT 282
           EEGPGWTILRDDFMMGASMKDWDKESDGPDDSRPESASDSDT
Sbjct: 241 EEGPGWTILRDDFMMGASMKDWDKESDGPDDSRPESASDSDT 282


>gi|5453567 craniofacial development protein 1 [Homo sapiens]
          Length = 299

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 64/252 (25%), Positives = 100/252 (39%), Gaps = 42/252 (16%)

Query: 7   DSRVSEEENLKKTPKKKMKMVT--------GAVASVLEDEATDTSDSEGSCGSEKDHFYS 58
           +  V  EE  +KT  KK K  +        G ++   E+E    S+SEGS   E      
Sbjct: 36  EDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEE------ 89

Query: 59  DDDAIEADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKL 118
           +DDA E +    +E   K+ E+             +  A  LN   P+SK     + KK 
Sbjct: 90  EDDAAEQEKGIGSEDARKKKED-------------ELWASFLNDVGPKSKVPPSTQVKKG 136

Query: 119 EKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLF---N 175
           E+ +E    + L K ++ +K  E E +   K      +E     +  AT    + F   N
Sbjct: 137 EETEETSSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQN 196

Query: 176 AVQKHQKNVDEKVKE--AGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKA 233
             +K Q NV   +    AGS +++ + +          S L G  G+  +  S+ +K K 
Sbjct: 197 EKEKPQANVPSALPSLPAGSGLKRSSGM----------SSLLGKIGAKKQKMSTLEKSKL 246

Query: 234 KQTEVKSEEGPG 245
                K EEG G
Sbjct: 247 DWESFKEEEGIG 258


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 48/216 (22%), Positives = 98/216 (45%), Gaps = 13/216 (6%)

Query: 64   EADSEGDAEPCDKEN---ENDGESSVGTNMGWADAMAKVLNKK----TPESKPTILVKNK 116
            E ++E +AE   ++    E + +  + T      + AKV +K     +PES+P    + +
Sbjct: 1001 EREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQ 1060

Query: 117  KLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNA 176
             LE  KE  ++E  E+ ++ ++  E E     + +  +++E E N+Q    R       A
Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVA 1120

Query: 177  VQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQT 236
            +++ +  V +K +      RKR ++ S+V+ +        ++   + +   R  P+ + T
Sbjct: 1121 IKRKRPFVLKKKRG-----RKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPT 1175

Query: 237  -EVKSEEGPGWTILRDDFMMGASMKDWDKESDGPDD 271
             E++ EE     +LR  F      K   +E +G D+
Sbjct: 1176 CEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDN 1211


>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
           sapiens]
          Length = 908

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 60/276 (21%), Positives = 117/276 (42%), Gaps = 31/276 (11%)

Query: 14  ENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGDAEP 73
           E+LK TPK    ++      V +++++ +S S  S  SE D   SD D+ ++ SE  +E 
Sbjct: 645 EHLKNTPK----VIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSE- 699

Query: 74  CDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKI 133
                E+D  S    +   A+ + K  + KT   +   L++N++    K+K   ER ++ 
Sbjct: 700 -----ESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQK---ERRQEH 751

Query: 134 KQRDKRLEWEMMCRVKPDVVQDKETERN--LQRIATRGVVQLFNAVQKHQKNVDEKV--- 188
             ++ R E E       D        R+   +  + + V    N   +   + D+++   
Sbjct: 752 GHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHID 811

Query: 189 --KEAGSSMRKRAKLISTVSKKD-FISVLRGMDGSTNETASSRKKPKAKQTEVKSEEGPG 245
              + G   +KR +  ++ S+ +     ++  +    +  S  K+   K +  +S+E   
Sbjct: 812 LENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDE--- 868

Query: 246 WTILRDDFMMGASMKDWDKESDGPDDSRPESASDSD 281
                D +  GA  + W+K S   + SR ES  + D
Sbjct: 869 -----DRYQNGAERR-WEKSSRYSEQSR-ESKKNQD 897


>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
          Length = 888

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 63/271 (23%), Positives = 105/271 (38%), Gaps = 25/271 (9%)

Query: 23  KMKMVTGAVASVLEDEATDTSD-SEGSCGSEKDHFYSDDDAIEADSEGDAEPCDKENEND 81
           K + V    AS+LE    D+SD S+   G   D   S + + +A  +     C    EN 
Sbjct: 6   KRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDASKDSGEGSCSDSEENI 65

Query: 82  GESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLE-----------KEKEKLKQERL 130
            E  +  ++   +   K   ++   S    L+K +K E           KEKEK K++  
Sbjct: 66  LEEELNEDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEK 125

Query: 131 EKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATR-GVVQLFNAVQKHQKNVDEKVK 189
           EK K+R+K  E       K  V ++          AT    V    +V       +E+V 
Sbjct: 126 EKEKEREKEKE-------KATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQVS 178

Query: 190 EAGS-SMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTEVKSEEGPGWTI 248
           E    ++R+   L+  VS ++    L  MD   +E  +  +    K+    + +  G   
Sbjct: 179 EPKKWNLRRNRPLLDFVSMEE----LNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDG 234

Query: 249 LRDDFMMGASMKDWDKESDGPDDSRPESASD 279
             +D     S  D D+  +G D+     AS+
Sbjct: 235 DNEDDEDEGSGSDEDENDEGNDEDHSSPASE 265


>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
          Length = 948

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 63/271 (23%), Positives = 105/271 (38%), Gaps = 25/271 (9%)

Query: 23  KMKMVTGAVASVLEDEATDTSD-SEGSCGSEKDHFYSDDDAIEADSEGDAEPCDKENEND 81
           K + V    AS+LE    D+SD S+   G   D   S + + +A  +     C    EN 
Sbjct: 6   KRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDASKDSGEGSCSDSEENI 65

Query: 82  GESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLE-----------KEKEKLKQERL 130
            E  +  ++   +   K   ++   S    L+K +K E           KEKEK K++  
Sbjct: 66  LEEELNEDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEK 125

Query: 131 EKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATR-GVVQLFNAVQKHQKNVDEKVK 189
           EK K+R+K  E       K  V ++          AT    V    +V       +E+V 
Sbjct: 126 EKEKEREKEKE-------KATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQVS 178

Query: 190 EAGS-SMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTEVKSEEGPGWTI 248
           E    ++R+   L+  VS ++    L  MD   +E  +  +    K+    + +  G   
Sbjct: 179 EPKKWNLRRNRPLLDFVSMEE----LNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDG 234

Query: 249 LRDDFMMGASMKDWDKESDGPDDSRPESASD 279
             +D     S  D D+  +G D+     AS+
Sbjct: 235 DNEDDEDEGSGSDEDENDEGNDEDHSSPASE 265


>gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo
           sapiens]
          Length = 529

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 40/193 (20%), Positives = 90/193 (46%), Gaps = 20/193 (10%)

Query: 98  KVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIK----QRDKRLEWEMMC--RVKPD 151
           ++   K       +L  NK+ + +K+K +Q + +K+     ++ K +E  M C  ++K +
Sbjct: 321 EIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEE 380

Query: 152 VVQDKETERNLQR-IATRGVVQLFNAVQKHQK---NVDEKVKEAGSSMRKR---AKLIST 204
             ++K+ ++  QR    + +++ +   +K Q+    ++++++E      KR   A  IS 
Sbjct: 381 EEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISR 440

Query: 205 VSKKDFISV-LRGMDGSTNETASSRKKPKAKQTEVKSEEGPGWTILRDDFMMGASMKDWD 263
             ++D   + L+ +D    E   S+K+ +  + + K E      + RD   +    K W+
Sbjct: 441 FQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN----NVSRDPSRLYKPTKGWE 496

Query: 264 KESD--GPDDSRP 274
           + +   GP  S P
Sbjct: 497 ERTKKIGPTGSGP 509


>gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
           sapiens]
          Length = 446

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 40/193 (20%), Positives = 90/193 (46%), Gaps = 20/193 (10%)

Query: 98  KVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIK----QRDKRLEWEMMC--RVKPD 151
           ++   K       +L  NK+ + +K+K +Q + +K+     ++ K +E  M C  ++K +
Sbjct: 238 EIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEE 297

Query: 152 VVQDKETERNLQR-IATRGVVQLFNAVQKHQK---NVDEKVKEAGSSMRKR---AKLIST 204
             ++K+ ++  QR    + +++ +   +K Q+    ++++++E      KR   A  IS 
Sbjct: 298 EEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISR 357

Query: 205 VSKKDFISV-LRGMDGSTNETASSRKKPKAKQTEVKSEEGPGWTILRDDFMMGASMKDWD 263
             ++D   + L+ +D    E   S+K+ +  + + K E      + RD   +    K W+
Sbjct: 358 FQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN----NVSRDPSRLYKPTKGWE 413

Query: 264 KESD--GPDDSRP 274
           + +   GP  S P
Sbjct: 414 ERTKKIGPTGSGP 426


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 42/169 (24%), Positives = 76/169 (44%), Gaps = 18/169 (10%)

Query: 11  SEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGD 70
           S+ +  ++T K K+ + TG + +  E   T T+  + + G +K          +   +G+
Sbjct: 272 SQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKD-------KKKKKGE 324

Query: 71  AEPCDKENENDGESSVGTNMGWADAMAKVLN-----KKTPESKPTILVKNKKLEKEKEKL 125
            E  +KE E     S  T     +A+AK+       K+  E +   L + +   KE+E+L
Sbjct: 325 KE--EKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERL 382

Query: 126 KQERLEKIKQRDK----RLEWEMMCRVKPDVVQDKETERNLQRIATRGV 170
           +QE+ E+ KQ++K    RL+ E     K         E  L+ +  +GV
Sbjct: 383 EQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGV 431



 Score = 32.0 bits (71), Expect = 0.63
 Identities = 50/226 (22%), Positives = 91/226 (40%), Gaps = 54/226 (23%)

Query: 36  EDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGDAEPCDKENENDGESSVGTNMGWADA 95
           E+E  +  +SEGS G E+D   SD+   ++    D +P  KE  +D E            
Sbjct: 548 EEEEEEEGESEGSEGDEEDEKVSDEK--DSGKTLDKKP-SKEMSSDSEY----------- 593

Query: 96  MAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQ-RDKRLEWEMMC-------- 146
                     +S      + +  +K K ++++ RLE  K    ++L   ++C        
Sbjct: 594 ----------DSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTG 643

Query: 147 ------RVKPDVVQDKETERNLQRI-ATRGVVQLFNAVQKHQKNVD-EKVK--------- 189
                 +++   VQD E     Q+I AT   ++  N   K  KN D E V+         
Sbjct: 644 KTKILDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLIIDT 703

Query: 190 ---EAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPK 232
              E+ S++R R   +  ++    + ++ G++  T E+ +  K  K
Sbjct: 704 PGHESFSNLRNRGSSLCDIAIL-VVDIMHGLEPQTIESINLLKSKK 748



 Score = 28.9 bits (63), Expect = 5.3
 Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 25/135 (18%)

Query: 44  DSEGSCGSEKDHFYSDDDAIEADSEGDAEP-CDKENENDGESSVGTNMGWADAMAKVLNK 102
           +S G  G E D F       + + +    P  +  NE+D            DA  K+   
Sbjct: 181 NSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDD------------DASFKI--- 225

Query: 103 KTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNL 162
           KT        V  KK EK++ + K+   EK K R K  E E +   K D  + KE++R  
Sbjct: 226 KT--------VAQKKAEKKERERKKRDEEKAKLR-KLKEKEELETGKKDQSKQKESQRKF 276

Query: 163 QRIATRGVVQLFNAV 177
           +    +  V +   V
Sbjct: 277 EEETVKSKVTVDTGV 291


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 3/119 (2%)

Query: 11  SEEENLKKTP---KKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADS 67
           SEEE ++ TP   KK  K+V     +V EDE  +  D +     ++D    DD+  E + 
Sbjct: 206 SEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEE 265

Query: 68  EGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLK 126
           E + E   KE     +  +       +A  + +    P +   + V N    K   +LK
Sbjct: 266 EEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELK 324


>gi|155722990 solute carrier family 4 (anion exchanger), member 1,
           adaptor protein [Homo sapiens]
          Length = 796

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 20/148 (13%)

Query: 100 LNKKTPESKPTIL-VKNK-KLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKE 157
           L  K PE  PT++ +K++ ++E+E+E+ ++E  EK +   K+LE   + R +P++    E
Sbjct: 627 LPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEI----E 682

Query: 158 TERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGM 217
            E  +Q +     +  F   Q H+       +E     +  +K           S+  G 
Sbjct: 683 PEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKT---------TSLCAGP 733

Query: 218 DGSTNETASSRKKPKAKQTEVKSEEGPG 245
             S NE   SR + K K+T      GPG
Sbjct: 734 SASKNEYEKSRGELKKKKT-----PGPG 756


>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
          Length = 1121

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 47/224 (20%), Positives = 87/224 (38%), Gaps = 12/224 (5%)

Query: 29  GAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGDAEPCDKENENDGESSVGT 88
           G V+S  +     T+D EGS  +        + +    S+         +E D  S++  
Sbjct: 157 GTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITR 216

Query: 89  NMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIK---------QRDKR 139
                +    V ++K P  K T + ++  L   +EK   E+   +           RD++
Sbjct: 217 EKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEK 276

Query: 140 LEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKRA 199
                + R K D  + +    + Q  + +      ++V        ++      S +K+ 
Sbjct: 277 DSLLNIARGKKDGEKTRRVSSHKQP-SLKATSDKEDSVPNMATETKDEQISGTVSCQKQP 335

Query: 200 KLISTVSKKDFISVLRG--MDGSTNETASSRKKPKAKQTEVKSE 241
            L +T  KKD +S +     DG  + T SS+K+P  K T VK +
Sbjct: 336 ALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 379


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 12/169 (7%)

Query: 114 KNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQR---IATRGV 170
           KNK  +KE+EK +++  EK ++R++  E E     + +  QDKE ER   R   I  +  
Sbjct: 413 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 472

Query: 171 VQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRK- 229
               +       N   + + +    R+R    S+ S +   ++ R    S +  + ++K 
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 532

Query: 230 KPKAKQTEVKSEEGPGWTILRDDFMMGASMKDWDKESDGPDDSRPESAS 278
           K + K+ +  SE        R +     SM+    + DG +     S S
Sbjct: 533 KKREKERDHISE--------RRERERSTSMRKSSNDRDGKEKLEKNSTS 573



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 30/163 (18%)

Query: 94  DAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVV 153
           D   K+  K+  + K     + K+ E+EKE+ K++   K K RDK  E         D  
Sbjct: 379 DTREKIKEKERVKEKD----REKEREREKEREKEKERGKNKDRDKERE--------KDRE 426

Query: 154 QDKETERNLQRIATRGVVQLFNAVQKHQKNVD-EKVKEAGSSMRK---RAKLISTVSKKD 209
           +DKE +R  +R             ++H+K+ D EK KE      +   R+K I    KKD
Sbjct: 427 KDKEKDRERER------------EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 474

Query: 210 FISVL--RGMDGSTNETASSRKKPKAKQTEVKSEEGPGWTILR 250
             S    R  + S    +SSR++ + +            TI R
Sbjct: 475 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 517



 Score = 36.6 bits (83), Expect = 0.025
 Identities = 49/224 (21%), Positives = 84/224 (37%), Gaps = 26/224 (11%)

Query: 64  EADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKE 123
           E D E + E   +E E + E   G N        K   K   + +     K  + +++KE
Sbjct: 392 EKDREKERE---REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 448

Query: 124 KLKQERLEKIKQRDKRLE------WEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAV 177
           K K++  EK +++D+  E       +   R  P         R+  R   R   +  +  
Sbjct: 449 KEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 508

Query: 178 QKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTE 237
            +  K +  K   + S   +  K      ++D IS  R  + ST+   SS  +   ++ E
Sbjct: 509 PRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 568

Query: 238 VKSEEGPGWTILRDDFMMGASMKDWDKESDGPDDSRPESASDSD 281
             S      T L++        K+ +KE   PD S  +   D D
Sbjct: 569 KNS------TSLKE--------KEHNKE---PDSSVSKEVDDKD 595


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 12/169 (7%)

Query: 114 KNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQR---IATRGV 170
           KNK  +KE+EK +++  EK ++R++  E E     + +  QDKE ER   R   I  +  
Sbjct: 297 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 356

Query: 171 VQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRK- 229
               +       N   + + +    R+R    S+ S +   ++ R    S +  + ++K 
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 416

Query: 230 KPKAKQTEVKSEEGPGWTILRDDFMMGASMKDWDKESDGPDDSRPESAS 278
           K + K+ +  SE        R +     SM+    + DG +     S S
Sbjct: 417 KKREKERDHISE--------RRERERSTSMRKSSNDRDGKEKLEKNSTS 457



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 30/163 (18%)

Query: 94  DAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVV 153
           D   K+  K+  + K     + K+ E+EKE+ K++   K K RDK  E         D  
Sbjct: 263 DTREKIKEKERVKEKD----REKEREREKEREKEKERGKNKDRDKERE--------KDRE 310

Query: 154 QDKETERNLQRIATRGVVQLFNAVQKHQKNVD-EKVKEAGSSMRK---RAKLISTVSKKD 209
           +DKE +R  +R             ++H+K+ D EK KE      +   R+K I    KKD
Sbjct: 311 KDKEKDRERER------------EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 358

Query: 210 FISVL--RGMDGSTNETASSRKKPKAKQTEVKSEEGPGWTILR 250
             S    R  + S    +SSR++ + +            TI R
Sbjct: 359 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 401



 Score = 36.6 bits (83), Expect = 0.025
 Identities = 49/224 (21%), Positives = 84/224 (37%), Gaps = 26/224 (11%)

Query: 64  EADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKE 123
           E D E + E   +E E + E   G N        K   K   + +     K  + +++KE
Sbjct: 276 EKDREKERE---REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 332

Query: 124 KLKQERLEKIKQRDKRLE------WEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAV 177
           K K++  EK +++D+  E       +   R  P         R+  R   R   +  +  
Sbjct: 333 KEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 392

Query: 178 QKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTE 237
            +  K +  K   + S   +  K      ++D IS  R  + ST+   SS  +   ++ E
Sbjct: 393 PRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 452

Query: 238 VKSEEGPGWTILRDDFMMGASMKDWDKESDGPDDSRPESASDSD 281
             S      T L++        K+ +KE   PD S  +   D D
Sbjct: 453 KNS------TSLKE--------KEHNKE---PDSSVSKEVDDKD 479


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 44/250 (17%), Positives = 109/250 (43%), Gaps = 27/250 (10%)

Query: 9   RVSEEENLKKTPKKKMKMVTGAVASVL---EDEATDTSDSEGSCGSEKDHFYSDDDAIEA 65
           +V++E+ + K  +++   ++ AV       E+E     +   +  +EK     +   I  
Sbjct: 437 QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE 496

Query: 66  DSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKL 125
                 E  ++E E + E              K L K+  + +     K ++ ++E+++ 
Sbjct: 497 KQPSPEEIREREREKERERE------------KELEKEQEQERE----KEREKDRERQQE 540

Query: 126 KQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVD 185
           K++ LEK +++ + +E E     + ++ + KE E+ LQ++  +   +    ++K ++ ++
Sbjct: 541 KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQ---EKECELEKEREKLE 597

Query: 186 EKVKEAGSSMRKRAKLISTVS--KKDFISVLRGMDGSTNETASSRKKPKAKQTEVKSEEG 243
           EK++    ++    +   + +   K+   V    D + +E  ++   P   +TE +S   
Sbjct: 598 EKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEAT---PVVHETEPESGSQ 654

Query: 244 PGWTILRDDF 253
           P   +L   F
Sbjct: 655 PRPAVLSGYF 664


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 48/206 (23%), Positives = 88/206 (42%), Gaps = 19/206 (9%)

Query: 36  EDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGDAEPCDKENENDGESSVGTNMGWADA 95
           E E    +D E     EK+     +   E + EG+     ++ + DG+          DA
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETEREGER---GRDRQTDGQRERERQR---DA 155

Query: 96  MAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQD 155
             K   ++T   +     +N++ E+E+EK +QER E+ +QR+K  + E       +  ++
Sbjct: 156 -EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR---HSERGRE 211

Query: 156 KETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLR 215
           +E ER  +   T    Q      + +K   E+ K+A    R+RA    T   K+     R
Sbjct: 212 RERERETE-TETERKRQTDRERDRQRKTEREREKQA---ERERASERETERDKE-----R 262

Query: 216 GMDGSTNETASSRKKPKAKQTEVKSE 241
             +   +     R+K + +QT+ K +
Sbjct: 263 ERERDRDRDRDRRQKERERQTDRKRQ 288



 Score = 32.3 bits (72), Expect = 0.48
 Identities = 42/235 (17%), Positives = 92/235 (39%), Gaps = 11/235 (4%)

Query: 9   RVSEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADSE 68
           R  E E   +T  ++ +          + E      +E    SE++     +   E D +
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269

Query: 69  GDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQE 128
            D +   KE E   +              +   ++    +     + ++ E+E+E+ ++ 
Sbjct: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329

Query: 129 RLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKV 188
           + E  + R+K  E +   + + D  ++++T R  +R A R   +     ++ +++  E+ 
Sbjct: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER---ERERERERDRQSARERE 386

Query: 189 KEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTEVKSEEG 243
           +      R R K     ++KD        DG   ET   R++ K +++E   E G
Sbjct: 387 ERERDRDRDRQKERERQTEKD-------RDGQ-RETEKQREREKDRESERGRERG 433



 Score = 28.1 bits (61), Expect = 9.0
 Identities = 25/129 (19%), Positives = 59/129 (45%), Gaps = 20/129 (15%)

Query: 114 KNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQL 173
           + ++ ++EKE+ +Q   E+ +QR+K               + KE ER  +R   RG  + 
Sbjct: 95  RERQRDREKERERQTDRERDRQREKERN------------RQKERERETEREGERGRDRQ 142

Query: 174 FNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKA 233
            +  ++ ++  D + +    + R+R +      +K+     R  + +  E    R++ + 
Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKE-----REREKNRQE---RRERERQ 194

Query: 234 KQTEVKSEE 242
           ++ E K+E+
Sbjct: 195 REKENKTED 203


>gi|40807471 transcription termination factor, RNA polymerase II
           [Homo sapiens]
          Length = 1162

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 46/182 (25%), Positives = 83/182 (45%), Gaps = 33/182 (18%)

Query: 72  EPCDKENENDGESSVGT-----NMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLK 126
           +P  KE+    +S   +     +  W     KVL+K    +    L+K +  EK+ +K +
Sbjct: 96  DPDSKEHSVSNKSQHASETFHHSSNWLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQ 155

Query: 127 QERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDE 186
           +E+ +++  + K  + EMM             E++L    + G+V      +K Q  V E
Sbjct: 156 REKGDQLFDQKKEQKPEMM-------------EKDL----SSGLVP-----KKKQSVVQE 193

Query: 187 KVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNE----TASSRKKPKAKQTEVKSEE 242
           K +E G+ ++  A+   T  K+DF S ++      NE    +ASS++K   K  +V+ E 
Sbjct: 194 KKQEEGAEIQCEAETGGT-HKRDF-SEIKSQQCQGNELTRPSASSQEKSSGKSQDVQRES 251

Query: 243 GP 244
            P
Sbjct: 252 EP 253


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 48/190 (25%), Positives = 80/190 (42%), Gaps = 13/190 (6%)

Query: 14  ENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGDAEP 73
           EN KK  +K  + +     S  +         + SC S      SD  +  +DSE     
Sbjct: 67  ENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSE----- 121

Query: 74  CDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNK-KLEKEKEKLKQERLEK 132
            D+E +         N  +  + +   ++   ESK ++  K K K E EKEK  +   +K
Sbjct: 122 -DEEKKQGKRRKKKKNRSYKSSQSST-HESESESKESVKKKKKSKDETEKEKDVRSLSKK 179

Query: 133 IKQR---DKRLEWEMMCRVK-PDVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKV 188
            K+    DK L  E        + VQ K+  R  +R   +  V+     ++H+K+  +K 
Sbjct: 180 RKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKK-KKKKQHKKHSKKKK 238

Query: 189 KEAGSSMRKR 198
           K++GSS + R
Sbjct: 239 KKSGSSHKSR 248



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 31/151 (20%), Positives = 67/151 (44%), Gaps = 21/151 (13%)

Query: 7   DSRVSEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCG----SEKDHFYSDDDA 62
           +S   + E  KK  KK  +  + + +S     ++D+ D E   G     +K+  Y    +
Sbjct: 85  ESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQS 144

Query: 63  IEADSEGDA-EPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKP------------ 109
              +SE ++ E   K+ ++  E+    ++    +++K   K  P+ KP            
Sbjct: 145 STHESESESKESVKKKKKSKDETEKEKDV---RSLSKKRKKSYPDDKPLSSESSSESDYE 201

Query: 110 -TILVKNKKLEKEKEKLKQERLEKIKQRDKR 139
             +  K K+  +E+E+ K++  +K K++ K+
Sbjct: 202 EDVQAKKKRRCEEREQAKEKVKKKKKKQHKK 232


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 30/144 (20%), Positives = 71/144 (49%), Gaps = 15/144 (10%)

Query: 102 KKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERN 161
           +K  E +  I  + KK+ +++EK+ ++  EKI++ +KR E E M R +  + + +E  R 
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQ--EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494

Query: 162 LQRIATRGVVQLFNAVQKHQKNV---DEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMD 218
            +++  +        ++K ++ V   +EK++E    +R++ + +    +K     +R  +
Sbjct: 495 KEKMHEQE-----EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK-----IREQE 544

Query: 219 GSTNETASSRKKPKAKQTEVKSEE 242
               E     ++ K  + E + E+
Sbjct: 545 EMWREEEKMHEQEKIWEEEKRQEQ 568



 Score = 35.0 bits (79), Expect = 0.074
 Identities = 26/142 (18%), Positives = 64/142 (45%), Gaps = 1/142 (0%)

Query: 102 KKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERN 161
           +K  E +  I  + +K+ +++EK++++  +  +Q +   E E   R + +++ +KE +  
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366

Query: 162 LQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGST 221
            Q        +     ++     +EK++E    M ++ K+     K+     +R  +   
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 426

Query: 222 NETASS-RKKPKAKQTEVKSEE 242
            + A   R++ K ++ E K  E
Sbjct: 427 EQEAKMWRQEEKIREQEEKIRE 448



 Score = 33.1 bits (74), Expect = 0.28
 Identities = 27/143 (18%), Positives = 73/143 (51%), Gaps = 14/143 (9%)

Query: 101 NKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRL-EWEMMCRVKPDVVQDKETE 159
           N+   + +  +  + +K+++ +EK+ QE+ EKI+++++++ E E   R + +++ +KE +
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKI-QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350

Query: 160 RNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDG 219
              Q        ++    ++  +  +E + E    MR++ +++    +K     +R ++ 
Sbjct: 351 MRRQE-------EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK-----IRELEE 398

Query: 220 STNETASSRKKPKAKQTEVKSEE 242
             +E    R++ + +Q E K  E
Sbjct: 399 KMHEQEKIREQEEKRQEEEKIRE 421



 Score = 30.8 bits (68), Expect = 1.4
 Identities = 18/107 (16%), Positives = 51/107 (47%)

Query: 92  WADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPD 151
           W +   +    K    +  I  + +K+ +++EK++++  ++ +Q +K  + E   R + +
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619

Query: 152 VVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKR 198
            +Q++E +   Q    R   ++    ++     +EK+ E    M+++
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666


>gi|41406057 amyloid beta A4 protein isoform c precursor [Homo
           sapiens]
          Length = 695

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 26/174 (14%)

Query: 31  VASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGDAEPCDKENENDGESSVGTNM 90
           VA V E+EA D  D E            D D +E ++E   EP ++  E     +  T  
Sbjct: 234 VAEVEEEEADDDEDDE------------DGDEVEEEAE---EPYEEATERTTSIATTTTT 278

Query: 91  GWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKP 150
                   V    T  S P  +  +K LE   ++ +    +K K+R +    E M +V  
Sbjct: 279 TTESVEEVVRVPTTAASTPDAV--DKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMR 336

Query: 151 DVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLIST 204
           +  + +   +NL +   + V+Q F      Q+ V+   +EA +   +R +L+ T
Sbjct: 337 EWEEAERQAKNLPKADKKAVIQHF------QEKVESLEQEAAN---ERQQLVET 381


>gi|209915570 amyloid beta A4 protein isoform e precursor [Homo
           sapiens]
          Length = 639

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 26/174 (14%)

Query: 31  VASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGDAEPCDKENENDGESSVGTNM 90
           VA V E+EA D  D E            D D +E ++E   EP ++  E     +  T  
Sbjct: 178 VAEVEEEEADDDEDDE------------DGDEVEEEAE---EPYEEATERTTSIATTTTT 222

Query: 91  GWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKP 150
                   V    T  S P  +  +K LE   ++ +    +K K+R +    E M +V  
Sbjct: 223 TTESVEEVVRVPTTAASTPDAV--DKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMR 280

Query: 151 DVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLIST 204
           +  + +   +NL +   + V+Q F      Q+ V+   +EA +   +R +L+ T
Sbjct: 281 EWEEAERQAKNLPKADKKAVIQHF------QEKVESLEQEAAN---ERQQLVET 325


>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
          Length = 1217

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 23/167 (13%)

Query: 77  ENENDGESSVGTNMGWADAMAKV--LNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIK 134
           + E  GE S        DA  K+  + ++  E K  I      +++EKE+L  ER E+IK
Sbjct: 245 KRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKI----SAMKEEKEQLSAERQEQIK 300

Query: 135 QRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSS 194
           QR K         +K   +QD+    + QR       +L    QK  + ++EK KE   +
Sbjct: 301 QRTK-------LELKAKDLQDELAGNSEQR------KRLLKERQKLLEKIEEKQKELAET 347

Query: 195 MRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTEVKSE 241
             K     ++V +K+   + R    +   T    K+ +  Q   K E
Sbjct: 348 EPK----FNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEE 390


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 62/264 (23%), Positives = 99/264 (37%), Gaps = 34/264 (12%)

Query: 4   AAPDSRVSEEENLKKTPKKKMKMVTGA-VASVLEDEA-TDTSDSEGSCGSEKDHFYSDDD 61
           ++P       E L K  ++K K+ +   V   L+ E  T     E     E++   + D 
Sbjct: 493 SSPSVSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDK 552

Query: 62  AIEADSEGDAEPCDKENENDGESSVGTNMGWADAMA-------KVLNKKTPESKPTILVK 114
           + E D         KE E D E+   T   W + +        K   K+  +  P + +K
Sbjct: 553 SKEKDKV-------KEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLK 605

Query: 115 N------------KKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNL 162
           +            KK ++EK K  +++ EK K +DK  E +M     P V+  KE    L
Sbjct: 606 DGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPL 665

Query: 163 QRIATRGVV-----QLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGM 217
              AT   V      L   + +      EKVKE      K+ K      +K+     R  
Sbjct: 666 FSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREK 725

Query: 218 DGSTNETASSRKKPKAKQTEVKSE 241
           +    E    ++K K K  ++K E
Sbjct: 726 EKRERE-KREKEKEKHKHEKIKVE 748


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 26/108 (24%), Positives = 54/108 (50%), Gaps = 7/108 (6%)

Query: 52  EKDHFYSDDDAIEADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTI 111
           ++ H   DD   E + E D    ++++E+  +   GT+ G  D        +  E +   
Sbjct: 473 DRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQ-----EDEEDEEEGHG 527

Query: 112 LVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETE 159
           L  N++ E+E++K ++E  E  ++R++R   E+   + PD  +++E E
Sbjct: 528 LSLNQEEEEEEDKEEEEEEEDEERREERA--EVGAPLSPDHSEEEEEE 573


>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
           sapiens]
          Length = 645

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 41/195 (21%), Positives = 82/195 (42%), Gaps = 27/195 (13%)

Query: 5   APDSRVSEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIE 64
           +P S     E  ++T  + ++ ++       + + T T D+  S         S   +  
Sbjct: 471 SPSSEAKAGEGHRRTMSQDLRQLS-------DSQRTSTYDNVPSLPGSPGEEASALSSQA 523

Query: 65  ADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEK 124
            DS+GD           G+ + G      D++ +++               ++L KE E 
Sbjct: 524 CDSKGDTLASPNSETGPGKKNSGEEE--IDSLQRMV---------------QELRKEIET 566

Query: 125 LKQERLEKIKQRDKRLE--WEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKHQK 182
            KQ   E+IK  +K     W  + R+  ++ ++K+    L+ I+ R + +    V+K  K
Sbjct: 567 QKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALE-ISLRNMERSREDVEKRNK 625

Query: 183 NVDEKVKEAGSSMRK 197
            ++E+VKE   SM++
Sbjct: 626 ALEEEVKEFVKSMKE 640


>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
           sapiens]
          Length = 638

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 41/195 (21%), Positives = 82/195 (42%), Gaps = 27/195 (13%)

Query: 5   APDSRVSEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIE 64
           +P S     E  ++T  + ++ ++       + + T T D+  S         S   +  
Sbjct: 464 SPSSEAKAGEGHRRTMSQDLRQLS-------DSQRTSTYDNVPSLPGSPGEEASALSSQA 516

Query: 65  ADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEK 124
            DS+GD           G+ + G      D++ +++               ++L KE E 
Sbjct: 517 CDSKGDTLASPNSETGPGKKNSGEEE--IDSLQRMV---------------QELRKEIET 559

Query: 125 LKQERLEKIKQRDKRLE--WEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKHQK 182
            KQ   E+IK  +K     W  + R+  ++ ++K+    L+ I+ R + +    V+K  K
Sbjct: 560 QKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALE-ISLRNMERSREDVEKRNK 618

Query: 183 NVDEKVKEAGSSMRK 197
            ++E+VKE   SM++
Sbjct: 619 ALEEEVKEFVKSMKE 633


>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 34/148 (22%), Positives = 67/148 (45%), Gaps = 11/148 (7%)

Query: 98  KVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDK-RLEWEMMCRVKPDVVQDK 156
           K  NK   +++  +    K +E+ KEK  Q  LE ++ R+K +       +++  + +DK
Sbjct: 363 KAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDK 422

Query: 157 ETERNLQRIATRG------VVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDF 210
           E     + I  +            NA++K ++  ++K+KE   S+++  + +    K+  
Sbjct: 423 EKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQK-EKESR 481

Query: 211 ISVLRGMDGSTNETASSRKKPKAKQTEV 238
              L G   S NE   +R K    Q+E+
Sbjct: 482 EKELMGFSKSVNE---ARSKMDVAQSEL 506


>gi|12711676 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3p [Homo sapiens]
          Length = 476

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 25/86 (29%), Positives = 50/86 (58%), Gaps = 4/86 (4%)

Query: 113 VKNKKLEKEK--EKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGV 170
           +KN+KLEK++  E+ ++ER  +  ++ +  E E   R + +  + KET++  ++IA + V
Sbjct: 221 IKNRKLEKQRIREEKREERRRRELEKKRLREEEKRRRREEERCKKKETDKQ-KKIAEKEV 279

Query: 171 -VQLFNAVQKHQKNVDEKVKEAGSSM 195
            ++L    +K ++   EK KE G  +
Sbjct: 280 RIKLLKKPEKGEEPTTEKPKERGEEI 305


>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 34/148 (22%), Positives = 67/148 (45%), Gaps = 11/148 (7%)

Query: 98  KVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDK-RLEWEMMCRVKPDVVQDK 156
           K  NK   +++  +    K +E+ KEK  Q  LE ++ R+K +       +++  + +DK
Sbjct: 363 KAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDK 422

Query: 157 ETERNLQRIATRG------VVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDF 210
           E     + I  +            NA++K ++  ++K+KE   S+++  + +    K+  
Sbjct: 423 EKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQK-EKESR 481

Query: 211 ISVLRGMDGSTNETASSRKKPKAKQTEV 238
              L G   S NE   +R K    Q+E+
Sbjct: 482 EKELMGFSKSVNE---ARSKMDVAQSEL 506


>gi|18375525 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3pdelta [Homo sapiens]
          Length = 443

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 25/86 (29%), Positives = 50/86 (58%), Gaps = 4/86 (4%)

Query: 113 VKNKKLEKEK--EKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGV 170
           +KN+KLEK++  E+ ++ER  +  ++ +  E E   R + +  + KET++  ++IA + V
Sbjct: 188 IKNRKLEKQRIREEKREERRRRELEKKRLREEEKRRRREEERCKKKETDKQ-KKIAEKEV 246

Query: 171 -VQLFNAVQKHQKNVDEKVKEAGSSM 195
            ++L    +K ++   EK KE G  +
Sbjct: 247 RIKLLKKPEKGEEPTTEKPKERGEEI 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.304    0.122    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,753,820
Number of Sequences: 37866
Number of extensions: 488387
Number of successful extensions: 4276
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 472
Number of HSP's that attempted gapping in prelim test: 3047
Number of HSP's gapped (non-prelim): 1323
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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