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Search of human proteins with 126090663
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
(3571 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 7274 0.0
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 3643 0.0
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 500 e-141
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 500 e-141
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 500 e-140
gi|52485606 formin-like 2 [Homo sapiens] 90 5e-17
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 87 4e-16
gi|33356148 formin-like 1 [Homo sapiens] 85 1e-15
gi|153792074 proline rich 12 [Homo sapiens] 85 1e-15
gi|150417989 cyclin K isoform 1 [Homo sapiens] 82 7e-15
gi|157168329 formin 1 [Homo sapiens] 82 1e-14
gi|56549694 enabled homolog isoform a [Homo sapiens] 81 2e-14
gi|39930375 enabled homolog isoform b [Homo sapiens] 81 2e-14
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 80 3e-14
gi|47132519 Ras association and pleckstrin homology domains 1 is... 80 3e-14
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 79 8e-14
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 79 8e-14
gi|11386183 WAS protein family, member 2 [Homo sapiens] 78 2e-13
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 77 4e-13
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 77 4e-13
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 77 4e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 76 5e-13
gi|145309324 FH2 domain containing 1 [Homo sapiens] 76 5e-13
gi|210032580 SET domain containing 1B [Homo sapiens] 76 5e-13
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 75 9e-13
gi|115511042 zinc finger protein 493 isoform 1 [Homo sapiens] 75 2e-12
gi|115511044 zinc finger protein 493 isoform 3 [Homo sapiens] 75 2e-12
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 75 2e-12
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 75 2e-12
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 75 2e-12
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 7274 bits (18873), Expect = 0.0
Identities = 3571/3571 (100%), Positives = 3571/3571 (100%)
Query: 1 METCDSPPISRQENGQSTSKLCGTTQLDNEVPEKVAGMEPDRENSSTDDNLKTDERKSEA 60
METCDSPPISRQENGQSTSKLCGTTQLDNEVPEKVAGMEPDRENSSTDDNLKTDERKSEA
Sbjct: 1 METCDSPPISRQENGQSTSKLCGTTQLDNEVPEKVAGMEPDRENSSTDDNLKTDERKSEA 60
Query: 61 LLGFSVENAAATQVTSAKEIPCNECATSFPSLQKYMEHHCPNARLPVLKDDNESEISELE 120
LLGFSVENAAATQVTSAKEIPCNECATSFPSLQKYMEHHCPNARLPVLKDDNESEISELE
Sbjct: 61 LLGFSVENAAATQVTSAKEIPCNECATSFPSLQKYMEHHCPNARLPVLKDDNESEISELE 120
Query: 121 DSDVENLTGEIVYQPDGSAYIIEDSKESGQNAQTGANSKLFSTAMFLDSLASAGEKSDQS 180
DSDVENLTGEIVYQPDGSAYIIEDSKESGQNAQTGANSKLFSTAMFLDSLASAGEKSDQS
Sbjct: 121 DSDVENLTGEIVYQPDGSAYIIEDSKESGQNAQTGANSKLFSTAMFLDSLASAGEKSDQS 180
Query: 181 ASAPMSFYPQIINTFHIASSLGKPFTADQAFPNTSALAGVGPVLHSFRVYDLRHKREKDY 240
ASAPMSFYPQIINTFHIASSLGKPFTADQAFPNTSALAGVGPVLHSFRVYDLRHKREKDY
Sbjct: 181 ASAPMSFYPQIINTFHIASSLGKPFTADQAFPNTSALAGVGPVLHSFRVYDLRHKREKDY 240
Query: 241 LTSDGSAKNSCVSKDVPNNVDLSKFDGCVSDGKRKPVLMCFLCKLSFGYIRSFVTHAVHD 300
LTSDGSAKNSCVSKDVPNNVDLSKFDGCVSDGKRKPVLMCFLCKLSFGYIRSFVTHAVHD
Sbjct: 241 LTSDGSAKNSCVSKDVPNNVDLSKFDGCVSDGKRKPVLMCFLCKLSFGYIRSFVTHAVHD 300
Query: 301 HRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPHFSTTNLIGPDPTF 360
HRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPHFSTTNLIGPDPTF
Sbjct: 301 HRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPHFSTTNLIGPDPTF 360
Query: 361 RGLWSAFHVENGDSLPAGFAFLKGSASTSSSAEQPLGITQMPKAEVNLGGLSSLVVNTPI 420
RGLWSAFHVENGDSLPAGFAFLKGSASTSSSAEQPLGITQMPKAEVNLGGLSSLVVNTPI
Sbjct: 361 RGLWSAFHVENGDSLPAGFAFLKGSASTSSSAEQPLGITQMPKAEVNLGGLSSLVVNTPI 420
Query: 421 TSVSLSHSSSESSKMSESKDQENNCERPKESNVLHPNGECPVKSEPTEPGDEDEEDAYSN 480
TSVSLSHSSSESSKMSESKDQENNCERPKESNVLHPNGECPVKSEPTEPGDEDEEDAYSN
Sbjct: 421 TSVSLSHSSSESSKMSESKDQENNCERPKESNVLHPNGECPVKSEPTEPGDEDEEDAYSN 480
Query: 481 ELDDEEVLGELTDSIGNKDFPLLNQSISPLSSSVLKFIEKGTSSSSATVSDDTEKKKQTA 540
ELDDEEVLGELTDSIGNKDFPLLNQSISPLSSSVLKFIEKGTSSSSATVSDDTEKKKQTA
Sbjct: 481 ELDDEEVLGELTDSIGNKDFPLLNQSISPLSSSVLKFIEKGTSSSSATVSDDTEKKKQTA 540
Query: 541 AVRASGSVASNYGISGKDFADASASKDSATAAHPSEIARGDEDSSATPHQHGFTPSTPGT 600
AVRASGSVASNYGISGKDFADASASKDSATAAHPSEIARGDEDSSATPHQHGFTPSTPGT
Sbjct: 541 AVRASGSVASNYGISGKDFADASASKDSATAAHPSEIARGDEDSSATPHQHGFTPSTPGT 600
Query: 601 PGPGGDGSPGSGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLE 660
PGPGGDGSPGSGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLE
Sbjct: 601 PGPGGDGSPGSGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLE 660
Query: 661 AHMKEKHPEPGGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQS 720
AHMKEKHPEPGGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQS
Sbjct: 661 AHMKEKHPEPGGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQS 720
Query: 721 DKHLNNVQNLQNGNGEQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVAR 780
DKHLNNVQNLQNGNGEQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVAR
Sbjct: 721 DKHLNNVQNLQNGNGEQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVAR 780
Query: 781 NLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLAPAEAELYQYYLAQNIGLTGMKLENPA 840
NLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLAPAEAELYQYYLAQNIGLTGMKLENPA
Sbjct: 781 NLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLAPAEAELYQYYLAQNIGLTGMKLENPA 840
Query: 841 DPQLMINPFQLDPATAAALAPGLGELSPYISDPALKLFQCAVCNKFTSDSLEALSVHVSS 900
DPQLMINPFQLDPATAAALAPGLGELSPYISDPALKLFQCAVCNKFTSDSLEALSVHVSS
Sbjct: 841 DPQLMINPFQLDPATAAALAPGLGELSPYISDPALKLFQCAVCNKFTSDSLEALSVHVSS 900
Query: 901 ERSLPEEEWRAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKSNEW 960
ERSLPEEEWRAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKSNEW
Sbjct: 901 ERSLPEEEWRAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKSNEW 960
Query: 961 RLKCIAIGNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQKQEGAVNPESCY 1020
RLKCIAIGNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQKQEGAVNPESCY
Sbjct: 961 RLKCIAIGNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQKQEGAVNPESCY 1020
Query: 1021 YYCAVCDYTTKVKLNLVQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPN 1080
YYCAVCDYTTKVKLNLVQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPN
Sbjct: 1021 YYCAVCDYTTKVKLNLVQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPN 1080
Query: 1081 ELETASLGARTCDDDLTEQHEEAEGAIKPTAVAEDDEKDTSERDNSEGKNSNKDSVSVAG 1140
ELETASLGARTCDDDLTEQHEEAEGAIKPTAVAEDDEKDTSERDNSEGKNSNKDSVSVAG
Sbjct: 1081 ELETASLGARTCDDDLTEQHEEAEGAIKPTAVAEDDEKDTSERDNSEGKNSNKDSVSVAG 1140
Query: 1141 GTQPLLLAKEEDVATKRSKPTEDNKFCHEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPV 1200
GTQPLLLAKEEDVATKRSKPTEDNKFCHEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPV
Sbjct: 1141 GTQPLLLAKEEDVATKRSKPTEDNKFCHEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPV 1200
Query: 1201 ICCPLCQDVLSNKMHLQLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSE 1260
ICCPLCQDVLSNKMHLQLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSE
Sbjct: 1201 ICCPLCQDVLSNKMHLQLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSE 1260
Query: 1261 RDTPAAVTAEGSGKYSGESPMDDKSMAGLEDSKANVEVKNEEQKPTKEPLEVSEWNKNSS 1320
RDTPAAVTAEGSGKYSGESPMDDKSMAGLEDSKANVEVKNEEQKPTKEPLEVSEWNKNSS
Sbjct: 1261 RDTPAAVTAEGSGKYSGESPMDDKSMAGLEDSKANVEVKNEEQKPTKEPLEVSEWNKNSS 1320
Query: 1321 KDVKIPDTLQDQLNEQQKRQPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAAT 1380
KDVKIPDTLQDQLNEQQKRQPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAAT
Sbjct: 1321 KDVKIPDTLQDQLNEQQKRQPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAAT 1380
Query: 1381 MCNLCQRSFRTFQALKKHLEAGHPELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQ 1440
MCNLCQRSFRTFQALKKHLEAGHPELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQ
Sbjct: 1381 MCNLCQRSFRTFQALKKHLEAGHPELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQ 1440
Query: 1441 EMEREYEVDHEGKASPVGSDSSSIPDDMGSEPKRTLPFRKGPNFTMEKFLDPSRPYKCTV 1500
EMEREYEVDHEGKASPVGSDSSSIPDDMGSEPKRTLPFRKGPNFTMEKFLDPSRPYKCTV
Sbjct: 1441 EMEREYEVDHEGKASPVGSDSSSIPDDMGSEPKRTLPFRKGPNFTMEKFLDPSRPYKCTV 1500
Query: 1501 CKESFTQKNILLVHYNSVSHLHKLKKVLQEASSPVPQETNSNTDNKPYKCSICNVAYSQS 1560
CKESFTQKNILLVHYNSVSHLHKLKKVLQEASSPVPQETNSNTDNKPYKCSICNVAYSQS
Sbjct: 1501 CKESFTQKNILLVHYNSVSHLHKLKKVLQEASSPVPQETNSNTDNKPYKCSICNVAYSQS 1560
Query: 1561 STLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNSPGQGMLDSMSLAAVNSKDTHL 1620
STLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNSPGQGMLDSMSLAAVNSKDTHL
Sbjct: 1561 STLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNSPGQGMLDSMSLAAVNSKDTHL 1620
Query: 1621 DAKELNKKQTPDLISAQPAHHPPQSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMT 1680
DAKELNKKQTPDLISAQPAHHPPQSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMT
Sbjct: 1621 DAKELNKKQTPDLISAQPAHHPPQSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMT 1680
Query: 1681 PEALLQFQQPQFLFPFYIPGTEFSLGPDLGLPGSATFGMPGMTGMAGSLLEDLKQQIQTQ 1740
PEALLQFQQPQFLFPFYIPGTEFSLGPDLGLPGSATFGMPGMTGMAGSLLEDLKQQIQTQ
Sbjct: 1681 PEALLQFQQPQFLFPFYIPGTEFSLGPDLGLPGSATFGMPGMTGMAGSLLEDLKQQIQTQ 1740
Query: 1741 HHVGQTQLQILQQQAQQYQATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSAD 1800
HHVGQTQLQILQQQAQQYQATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSAD
Sbjct: 1741 HHVGQTQLQILQQQAQQYQATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSAD 1800
Query: 1801 CQIMKDVPSYKEAEDISEKPEKPKQEFISEGEGLKEGKDTKKQKSLEPSIPPPRIASGAR 1860
CQIMKDVPSYKEAEDISEKPEKPKQEFISEGEGLKEGKDTKKQKSLEPSIPPPRIASGAR
Sbjct: 1801 CQIMKDVPSYKEAEDISEKPEKPKQEFISEGEGLKEGKDTKKQKSLEPSIPPPRIASGAR 1860
Query: 1861 GNAAKALLENFGFELVIQYNENRQKVQKKGKSGEGENTDKLECGTCGKLFSNVLILKSHQ 1920
GNAAKALLENFGFELVIQYNENRQKVQKKGKSGEGENTDKLECGTCGKLFSNVLILKSHQ
Sbjct: 1861 GNAAKALLENFGFELVIQYNENRQKVQKKGKSGEGENTDKLECGTCGKLFSNVLILKSHQ 1920
Query: 1921 EHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPV 1980
EHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPV
Sbjct: 1921 EHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPV 1980
Query: 1981 KIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQP 2040
KIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQP
Sbjct: 1981 KIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQP 2040
Query: 2041 VQHPALPPQLALQLPQMDALSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILR 2100
VQHPALPPQLALQLPQMDALSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILR
Sbjct: 2041 VQHPALPPQLALQLPQMDALSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILR 2100
Query: 2101 AYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLED 2160
AYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLED
Sbjct: 2101 AYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLED 2160
Query: 2161 IRIDPQPTSLEHYKSDASFSKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNL 2220
IRIDPQPTSLEHYKSDASFSKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNL
Sbjct: 2161 IRIDPQPTSLEHYKSDASFSKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNL 2220
Query: 2221 PTRVIVVWFQNARQKARKSYENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIF 2280
PTRVIVVWFQNARQKARKSYENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIF
Sbjct: 2221 PTRVIVVWFQNARQKARKSYENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIF 2280
Query: 2281 DLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGS 2340
DLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGS
Sbjct: 2281 DLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGS 2340
Query: 2341 GTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQ 2400
GTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQ
Sbjct: 2341 GTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQ 2400
Query: 2401 PQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTL 2460
PQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTL
Sbjct: 2401 PQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTL 2460
Query: 2461 ELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASS 2520
ELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASS
Sbjct: 2461 ELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASS 2520
Query: 2521 SHTTAPTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYL 2580
SHTTAPTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYL
Sbjct: 2521 SHTTAPTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYL 2580
Query: 2581 LDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFK 2640
LDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFK
Sbjct: 2581 LDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFK 2640
Query: 2641 AKSALESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIYFDYPSLPLTKIDLSSE 2700
AKSALESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIYFDYPSLPLTKIDLSSE
Sbjct: 2641 AKSALESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIYFDYPSLPLTKIDLSSE 2700
Query: 2701 NELASTVSTPVSKTAELSPKNLLSPSSFKAECSEDVENLNAPPAEAGYDQNKTDFDETSS 2760
NELASTVSTPVSKTAELSPKNLLSPSSFKAECSEDVENLNAPPAEAGYDQNKTDFDETSS
Sbjct: 2701 NELASTVSTPVSKTAELSPKNLLSPSSFKAECSEDVENLNAPPAEAGYDQNKTDFDETSS 2760
Query: 2761 INTAISDATTGDEGNTEMESTTGSSGDVKPALSPKEPKTLDTLPKPATTPTTEVCDDKFL 2820
INTAISDATTGDEGNTEMESTTGSSGDVKPALSPKEPKTLDTLPKPATTPTTEVCDDKFL
Sbjct: 2761 INTAISDATTGDEGNTEMESTTGSSGDVKPALSPKEPKTLDTLPKPATTPTTEVCDDKFL 2820
Query: 2821 FSLTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKSKSND 2880
FSLTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKSKSND
Sbjct: 2821 FSLTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKSKSND 2880
Query: 2881 RPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEK 2940
RPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEK
Sbjct: 2881 RPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEK 2940
Query: 2941 KFKINIGKPFMINQGGTEGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDR 3000
KFKINIGKPFMINQGGTEGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDR
Sbjct: 2941 KFKINIGKPFMINQGGTEGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDR 3000
Query: 3001 EKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLP 3060
EKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLP
Sbjct: 3001 EKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLP 3060
Query: 3061 PVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPP 3120
PVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPP
Sbjct: 3061 PVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPP 3120
Query: 3121 PPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSA 3180
PPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSA
Sbjct: 3121 PPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSA 3180
Query: 3181 LSVLGKVVGETHVDPIQLQALQNAIAGDPASFIGGQFLPYFIPGFASYFTPQLPGTVQGG 3240
LSVLGKVVGETHVDPIQLQALQNAIAGDPASFIGGQFLPYFIPGFASYFTPQLPGTVQGG
Sbjct: 3181 LSVLGKVVGETHVDPIQLQALQNAIAGDPASFIGGQFLPYFIPGFASYFTPQLPGTVQGG 3240
Query: 3241 YFPPVCGMESLFPYGPTMPQTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQKPV 3300
YFPPVCGMESLFPYGPTMPQTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQKPV
Sbjct: 3241 YFPPVCGMESLFPYGPTMPQTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQKPV 3300
Query: 3301 QAKTSKVESDQPQNSNDASETKEDKSTATESTKEEPQLESKSADFSDTYVVPFVKYEFIC 3360
QAKTSKVESDQPQNSNDASETKEDKSTATESTKEEPQLESKSADFSDTYVVPFVKYEFIC
Sbjct: 3301 QAKTSKVESDQPQNSNDASETKEDKSTATESTKEEPQLESKSADFSDTYVVPFVKYEFIC 3360
Query: 3361 RKCQMMFTDEDAAVNHQKSFCYFGQPLIDPQETVLRVPVSKYQCLACDVAISGNEALSQH 3420
RKCQMMFTDEDAAVNHQKSFCYFGQPLIDPQETVLRVPVSKYQCLACDVAISGNEALSQH
Sbjct: 3361 RKCQMMFTDEDAAVNHQKSFCYFGQPLIDPQETVLRVPVSKYQCLACDVAISGNEALSQH 3420
Query: 3421 LQSSLHKEKTIKQAMRNAKEHVRLLPHSVCSPNPNTTSTSQSAASSNNTYPHLSCFSMKS 3480
LQSSLHKEKTIKQAMRNAKEHVRLLPHSVCSPNPNTTSTSQSAASSNNTYPHLSCFSMKS
Sbjct: 3421 LQSSLHKEKTIKQAMRNAKEHVRLLPHSVCSPNPNTTSTSQSAASSNNTYPHLSCFSMKS 3480
Query: 3481 WPNILFQASARRAASPPSSPPSLSLPSTVTSSLCSTSGVQTSLPTESCSDESDSELSQKL 3540
WPNILFQASARRAASPPSSPPSLSLPSTVTSSLCSTSGVQTSLPTESCSDESDSELSQKL
Sbjct: 3481 WPNILFQASARRAASPPSSPPSLSLPSTVTSSLCSTSGVQTSLPTESCSDESDSELSQKL 3540
Query: 3541 EDLDNSLEVKAKPASGLDGNFNSIRMDMFSV 3571
EDLDNSLEVKAKPASGLDGNFNSIRMDMFSV
Sbjct: 3541 EDLDNSLEVKAKPASGLDGNFNSIRMDMFSV 3571
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 3643 bits (9446), Expect = 0.0
Identities = 2019/3826 (52%), Positives = 2508/3826 (65%), Gaps = 382/3826 (9%)
Query: 1 METCDSPPISRQENGQSTSKLCGTTQLDN-EVPEKVAGMEPDR-ENSSTDDNLKT--DER 56
ME CDSP +S ++NG + T+L++ +P+K + ME E+ D+L+ +ER
Sbjct: 1 MEGCDSPVVSGKDNGCGIPQHQQWTELNSTHLPDKPSSMEQSTGESHGPLDSLRAPFNER 60
Query: 57 KSEALLGFSVENAAATQVTSAKEIPCNECATSFPSLQKYMEHHCPNARLPV-LKDDNESE 115
+E S +A ++KE+ CNEC+ SF SLQ YMEHHCP+AR P L++++ S+
Sbjct: 61 LAE-----STASAGPPSEPASKEVTCNECSASFASLQTYMEHHCPSARPPPPLREESASD 115
Query: 116 ISEL--EDSDVENLTGEIVYQPDGSAYIIEDSKE---SGQNAQTGANSKLFSTAMFLDSL 170
E E+SDVENL GEIVYQPDGSAYI+E + G +G+ S + +FL+SL
Sbjct: 116 TGEEGDEESDVENLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGSGSGPLPS-LFLNSL 174
Query: 171 ASAGEKS-DQSASAPMSFYPQIINTFHIASSLGKPFTA-DQAFPNTSALAGVGPVLHSFR 228
AG K D S +AP+ YPQIINTFHIASS GK F DQAFPNTSALAG+ PVLHSFR
Sbjct: 175 PGAGGKQGDPSCAAPV--YPQIINTFHIASSFGKWFEGPDQAFPNTSALAGLSPVLHSFR 232
Query: 229 VYDLRHKREKDYLTSDGSAKNSCVSKDVPNNVDLSKFDGCVSDGKRKPVLMCFLCKLSFG 288
V+D+RHK KDYL SDGSAK+SCVSKDVPNNVDLSKFDG V GKRKP+LMCFLCKLSFG
Sbjct: 233 VFDVRHKSNKDYLNSDGSAKSSCVSKDVPNNVDLSKFDGFVLYGKRKPILMCFLCKLSFG 292
Query: 289 YIRSFVTHAVHDHRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEPKKSTSVYPHF 348
Y+RSFVTHAVHDHRMTL+++E+K+LSNK +SAIIQGIGKDKEPL+SFLEPK +P
Sbjct: 293 YVRSFVTHAVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEPLVSFLEPKNKNFQHPLV 352
Query: 349 STTNLIGPDPTFRGLWSAFHVENGDSLPAGFAFLKGSASTSSSAEQPLGITQMPKAEVNL 408
ST NLIGP +F G +S +E ++LPAG A + EQP P +NL
Sbjct: 353 STANLIGPGHSFYGKFSGIRMEGEEALPAGSA---------AGPEQPQAGLLTPSTLLNL 403
Query: 409 GGLSSLVVNTPITSVSLSHSSSESSKMSESKDQ-----------ENNCERPK------ES 451
GGL+S V+ TPITSV L +S +K SE KD + +C K E+
Sbjct: 404 GGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEA 463
Query: 452 NVLHPNGECPVKSEPTEPGDEDEEDA-----YSNELDDE------EVLGELTDSIGNKDF 500
E + E E +E+EED + +ELD+E E G S KD
Sbjct: 464 EEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDL 523
Query: 501 PLLNQSIS--PLSSSVLKFIEKGTSSSSATVSD-----DTEKKKQTAAVRASGSVASNYG 553
L NQSIS PL +VL+ + +GT+S+S+ + D ++ + + G V +N
Sbjct: 524 ALSNQSISNSPLMPNVLQTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEG-VRANVA 582
Query: 554 ISGK--DFADASASKDSATAAHPSEIARGDEDSSATPHQHGFTPSTPGTPGPGGDGSPGS 611
G+ DFAD SA+KD+ATA P+E GD+ HQH + G G+ GS
Sbjct: 583 EGGRRLDFADESANKDNATAPEPNESTEGDDGGFVPHHQHAGSLCELGV----GECPSGS 638
Query: 612 GIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPG 671
G+ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPG
Sbjct: 639 GVECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPG 698
Query: 672 GSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQ 731
GSCVYCK+GQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNN+QNLQ
Sbjct: 699 GSCVYCKSGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQ 758
Query: 732 NGNGEQVFGHSAPAPNTSL----------SGCGTPSPSKPKQKPTWRCEVCDYETNVARN 781
NG GEQVF H+A A ++ S CG PSP+KPK KPTWRCEVCDYETNVARN
Sbjct: 759 NGGGEQVFSHTAGAAAAAVAAAAAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARN 818
Query: 782 LRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGL----APAEAELYQYYLAQNIGLTGMKLE 837
LRIHMTSEKHMHNMMLLQQNM QIQHN HLGL +PAEAELYQYYLAQN+ L +K++
Sbjct: 819 LRIHMTSEKHMHNMMLLQQNMTQIQHNRHLGLGSLPSPAEAELYQYYLAQNMNLPNLKMD 878
Query: 838 NPA-DPQLMINPFQLDPA-TAAALAPGL------------------------GELSPYIS 871
+ A D Q M++ FQLDPA AA+ P L GE +
Sbjct: 879 SAASDAQFMMSGFQLDPAGPMAAMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTN 938
Query: 872 DPALKLFQCAVCNKFTSDSLEALSVHVSSERSLPEEEWRAVIGDIYQCKLCNYNTQLKAN 931
DP+LKLFQCAVCNKFT+D+L+ L +H++ ERSL E+EW+AV+GD YQCKLC YNTQLKAN
Sbjct: 939 DPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKAN 998
Query: 932 FQLHCKTDKHMQKYQLVAHIKEGGKSNEWRLKCIAIGNPVHLKCNACDYYTNSVDKLRLH 991
FQLHCKTDKH+QKYQLVAHIKEGGK+NEWRLKC+AIGNPVHLKCNACDYYTNS++KLRLH
Sbjct: 999 FQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIGNPVHLKCNACDYYTNSLEKLRLH 1058
Query: 992 TTNHRHEAALKLYKHLQKQEGAVNPESCYYYCAVCDYTTKVKLNLVQHVRSVKHQQTEGL 1051
T N RHEA+LKLYKHLQ+ E V ESCYY+C +C+Y+TK KLNL+QHVRS+KHQ++E L
Sbjct: 1059 TVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAKLNLIQHVRSMKHQRSESL 1118
Query: 1052 RKLQLHQQGLAPEEDNLSEIFFVKDCPPNELETASLGARTCDDDLTEQHEEAEGAIKPTA 1111
RKLQ Q+GL E+++L +IF ++ CP + E A + + +E A P
Sbjct: 1119 RKLQRLQKGLPEEDEDLGQIFTIRRCPSTDPEEA----------IEDVEGPSETAADPEE 1168
Query: 1112 VAEDDEKDTS----ERDNSEGKNSNKDSVSVAGGTQPLLLAKEEDVATKRSKPTEDNKFC 1167
+A+D E S E++ ++ ++K +S G + E +++KR K E+ K
Sbjct: 1169 LAKDQEGGASSSQAEKELTDSPATSK-RISFPGSS-------ESPLSSKRPKTAEEIK-- 1218
Query: 1168 HEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHLQLHLTHLHSVS 1227
EQ YQCPYC Y++ D +R+++H ++QHSVQP++ CPLCQD+L+NK+HLQLHLTHLHSV+
Sbjct: 1219 PEQMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHLHSVA 1278
Query: 1228 PDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKYSGESPMDDKSMA 1287
PDCVEKL+MTV P+++MP+SM LPAA ++ E +GK S K++
Sbjct: 1279 PDCVEKLIMTVTTPEMVMPSSMFLPAAVPDRDGNSN-----LEEAGKQPETSEDLGKNIL 1333
Query: 1288 GLEDSKANVEVKNEEQKP--TKEPLEVSEWNKNSSKDVKIPDTLQDQLNEQQKRQP-LSV 1344
++ + ++K P +E W K ++ K LQ NE ++P L V
Sbjct: 1334 PSASTEQSGDLKPSPADPGSVREDSGFICWKKGCNQVFKTSAALQTHFNEVHAKRPQLPV 1393
Query: 1345 SDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHP 1404
SDRHVYKYRCN CSLAFKT++KLQ+HSQYH IRAATMC LCQRSFRTFQALKKHLE H
Sbjct: 1394 SDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQRSFRTFQALKKHLETSHL 1453
Query: 1405 ELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSI 1464
ELSEA++QQLY L NG+L A + +DH + E ++E E D E K SP GSDS S+
Sbjct: 1454 ELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDLEDKQSPTGSDSGSV 1513
Query: 1465 PDDMGSEPKRTLPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKL 1524
+D GSEPKR LPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKL
Sbjct: 1514 QEDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKL 1573
Query: 1525 KKVLQEASSPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPS 1584
K+ LQE+++ P+ T+S DNKP+KC+ CNVAYSQSSTLEIHMRSVLHQTKARAAKLE +
Sbjct: 1574 KRALQESATGQPEPTSS-PDNKPFKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAA 1632
Query: 1585 GHVAGGHSIAANVN---------------------------SPGQGMLDSMSLAAVNSKD 1617
+ G +++++ +P +L + +V
Sbjct: 1633 SGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVGMPP 1692
Query: 1618 ----------THLDAKELNKKQTPDLISA------------------QPAHHPPQSPAQI 1649
+ + KE N+K+ D+I++ Q A Q+ AQ+
Sbjct: 1693 LGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQV 1752
Query: 1650 QMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQ-FLFPFYIPGTEFSLGPD 1708
Q LQ ELQQQAA Q Q NP LPHFPMT E LLQ QQ Q LFPFYIP EF L P+
Sbjct: 1753 QAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPE 1812
Query: 1709 LGLPGSATFGMPGMTGMAGSLLEDLKQQIQTQHHVGQTQLQILQQQAQQYQATQPQLQPQ 1768
+ LP T G +TG LLEDLK Q+Q Q+ QIL QQ Q QL
Sbjct: 1813 VSLP--VTSGALTLTGTGPGLLEDLKAQVQVPQ---QSHQQILPQQQQN------QLSIA 1861
Query: 1769 KQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISEKPEKPKQEFI 1828
+ P Q +++ ++K+++ K+ +++ + E PK E +
Sbjct: 1862 QSHSALLQPSQHPEKKNKLVIKEKE-----------KESQRERDSAEGGEGNTGPK-ETL 1909
Query: 1829 SEGEGLKEGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQK 1888
+ KE K+ EPS+ PPRIAS ARGNA KALLENFGFELVIQYNEN+QKVQK
Sbjct: 1910 PDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNENKQKVQK 1969
Query: 1889 K-GKSGEGENTDKLECGTCGKLFSNVLILKSHQEHVHGQFFPYAALEKFARQYREAYDKL 1947
K GK+ +GEN +KLEC +CGKLFSN+LILKSHQEHVH +FP+ LE+FA+QYR+ YDKL
Sbjct: 1970 KNGKTDQGENLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAKQYRDHYDKL 2029
Query: 1948 YPISPSSPETPPP--PPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP 2005
YP+ P +PE PPP PPPPPPLP APPQP+S T + P APP T P P P
Sbjct: 2030 YPLRPQTPEPPPPPPPPPPPPLPAAPPQPAS--------TPAIPASAPPITSPTIAPAQP 2081
Query: 2006 PPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLT 2065
+ P QL + ++LP+F +MMQ + LP QL QL ++ L ADL
Sbjct: 2082 ------------SVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLA 2129
Query: 2066 QLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQ 2125
QL Q Q L+P L+ Q KRPRTRITDDQL++LR YFDINNSPSEEQI+EMA+KSGL Q
Sbjct: 2130 QLYQHQ--LNPTLLQ-QQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQ 2186
Query: 2126 KVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQPTSLEHYKSDASFSKRSSR 2185
KVIKHWFRNTLFKERQRNKDSPYNFSNPPIT LE+++ID +P S E K + SKRSSR
Sbjct: 2187 KVIKHWFRNTLFKERQRNKDSPYNFSNPPITSLEELKIDSRPPSPEPPKQEYWGSKRSSR 2246
Query: 2186 TRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQAE 2245
TRFTDYQLRVLQDFFD NAYPKDDE EQLS +LNLPTRVIVVWFQNARQKARK+YENQ E
Sbjct: 2247 TRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGE 2306
Query: 2246 TKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTE 2305
KD E+RELTN+RYIRTSN+ YQCKKC++VF RIFDLI HQKK CYKDED++ QD+SQ E
Sbjct: 2307 GKDGERRELTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKDEDEEGQDDSQNE 2366
Query: 2306 DSMDATDQVVYKHCTVS-GQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYP 2364
DSMDA + + + S A +A AP+A++ + ++ + + E + K E
Sbjct: 2367 DSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAG 2426
Query: 2365 AEKP---------------KQSDPSPP-SQGTKPALPLASTSSDPPQ----ASTAQPQPQ 2404
EKP KQ P P Q +P + PQ S QP PQ
Sbjct: 2427 DEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQ 2486
Query: 2405 PQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTLELWQ 2464
PP+ P P + + +P PL S +LPPQL+ YQCDQC +AFP+ E WQ
Sbjct: 2487 APPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQ 2546
Query: 2465 EHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASSSHTT 2524
EHQ +HFL+AQNQF+H FL+R +DMP+M+FDP+NPL+ QLL ++ Q+P +++S +T
Sbjct: 2547 EHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPST 2606
Query: 2525 APTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSN 2584
PT+ +LKRKL++K + E + G GE+ RDKRLRTTITPEQLEILY+KYLLDSN
Sbjct: 2607 -PTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSN 2665
Query: 2585 PTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCPFCRALFKAKSA 2644
PTRKMLDHIA EVGLKKRVVQVWFQNTRARERKGQFRAVGPAQ+H+RCPFCRALFKAK+A
Sbjct: 2666 PTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGPAQAHRRCPFCRALFKAKTA 2725
Query: 2645 LESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIY--FDYPSLPLTKIDLSSENE 2702
LE+HIRSRHW+E K+AGY+L S ++ DGG + I+ + LP S ++
Sbjct: 2726 LEAHIRSRHWHEAKRAGYNLTLSAMLLDCDGGLQMKGDIFDGTSFSHLP------PSSSD 2779
Query: 2703 LASTVSTPVSKTAELSPKNLLSPSSFKAECSEDVENLNAPPAEAGYDQNKTDFDETSSIN 2762
+PVSKT ELSP+ LLSPSS K E ED E+ + +DQ K D D+ SS+N
Sbjct: 2780 GQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFESPSMSSVNLNFDQTKLDNDDCSSVN 2839
Query: 2763 TAISDATTGDEGNTEMESTTGSSGDVKPALSPKEPKTLDTLPKPATTPTTEVCDDKFLFS 2822
TAI+D TTGDEGN + +S TG + + K + +P E L K A +E +D+
Sbjct: 2840 TAITDTTTGDEGNADNDSATGIATETKSSSAPNE-----GLTKAAMMAMSEY-EDRLSSG 2893
Query: 2823 LTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPNPFGSSNPFKS-KSNDR 2881
L SP+ F K+ D+ + D SETSS+ADP SP+P S + KS S DR
Sbjct: 2894 LVSPAPSFYSKEYDN----------EGTVDYSETSSLADPCSPSPGASGSAGKSGDSGDR 2943
Query: 2882 PGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKK 2941
PG KRFRTQM+NLQLKVLK+CF+DYRTPTM ECE+LGN+IGLPKRVVQVWFQNARAKEKK
Sbjct: 2944 PGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKK 3003
Query: 2942 FKINIGKPFMINQGGTEGTKPECTLCGVKYSARLSIRDHIFSKQHISKVRETVGSQLDRE 3001
K+++ K F INQ EG K ECTLCG+KYSARLS+RDHIFS+QHISKV++T+GSQLD+E
Sbjct: 3004 SKLSMAKHFGINQTSYEGPKTECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKE 3063
Query: 3002 KDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLPP 3061
K+Y P TVRQLMAQQELDRIKKA++VLGL QQ GM D++ L ++LPTAYP L G+PP
Sbjct: 3064 KEYFDPATVRQLMAQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPP 3123
Query: 3062 VLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKP---LLQTP- 3117
VLLPG+N P SLPGF ++ LT P ++G P++ SP L S P KP L +P
Sbjct: 3124 VLLPGLNSP-SLPGFTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPT 3182
Query: 3118 ---------------------------PPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTK 3150
PPPPP PPP+ L QQ +Q+ + +K +
Sbjct: 3183 PAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKE 3242
Query: 3151 PNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKV-VGETHVDPIQLQALQNAIAGDP 3209
K K K E L K E K E ++A ++ + E VDP QLQALQ A+ DP
Sbjct: 3243 KEKAHKGKGEPLPVPKKE---KGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDP 3299
Query: 3210 ASFIGGQFLPYFIPGFASYFTPQLPGTVQGGYFPPVCGMESLFPYGPTMPQTLAGLSPGA 3269
+ + QFLPYF+PGF+ Y+ PQ+PG +Q GY P+ GME LFPY P + Q L GLSPG+
Sbjct: 3300 TALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGS 3359
Query: 3270 LLQQYQQYQQNLQESLQKQQKQQ-QEQQQKPVQAKTSKVE---------SDQPQNSNDAS 3319
LLQQYQQYQQ+LQE++Q+QQ++Q Q+QQQ+ VQ + K S + ++
Sbjct: 3360 LLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESP 3419
Query: 3320 ETKEDKSTATE------STKEEPQLESKSAD-FSDTYVVPFVKYEFICRKCQMMFTDEDA 3372
+ +E K+T E EEP+ ESKSAD D ++VP V+Y+ +CRKCQ F+DE+A
Sbjct: 3420 KPEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEA 3479
Query: 3373 AVNHQKSFCYFGQPLIDPQETVLRVPV--------------------SKYQCLACDVAIS 3412
A +H KS C+FGQ +++ QE VL VP Y CLAC+ A+
Sbjct: 3480 ARSHLKSLCFFGQSVVNLQEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALC 3539
Query: 3413 GNEALSQHLQSSLHKEKTIKQAMRNAKEHVRLLPHSVCSPNPNTTSTSQSAASSNNTYPH 3472
G EALSQHL+S+LHK +TI +A RNAKEH LLPHS C P+P+T STSQSAA SN++ P
Sbjct: 3540 GEEALSQHLESALHKHRTITRAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPP 3599
Query: 3473 LSC---------FSMKSWPNILFQASARRAASPPSSPPSLSLPSTVTSSLCSTSGVQTSL 3523
S S KSWP ++ +AS AA PPS PP LS STVTSS CSTSGVQ S+
Sbjct: 3600 PSAAAPSSASPHASRKSWPQVVSRAS---AAKPPSFPP-LSSSSTVTSSSCSTSGVQPSM 3655
Query: 3524 PTESCSDESDSELSQKLEDLDNSLEVKAKPASGLDGNFNSIRMDMF 3569
PT+ S+ESD++LSQK + + +E P+ D S+ D F
Sbjct: 3656 PTDDYSEESDTDLSQKSDGPASPVEGPKDPSCPKDSGLTSVGTDTF 3701
>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 500 bits (1288), Expect = e-141
Identities = 303/779 (38%), Positives = 403/779 (51%), Gaps = 98/779 (12%)
Query: 562 ASASKDSATAAHPSEIARGDED----------SSATPHQHGFTPSTPGTP-GPGGDGSPG 610
A S +A A P G E+ SS T + G P+ G+P P P
Sbjct: 360 AKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPY 419
Query: 611 SGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP 670
+ SL HM+++HSRNSCKTLKCPKCNWHYKYQQTL+ HM+EKHPE
Sbjct: 420 RLADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPES 479
Query: 671 GGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNL 730
C YC G HPRLARGESY CGYKP+RC+VCNYSTTTKGNLSIHMQSDKHL N+Q
Sbjct: 480 NSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGF 539
Query: 731 QNGNGEQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEK 790
Q G G G +P P SL + +PK K +W+C+VC YETN++RNLRIHMTSEK
Sbjct: 540 QAGPG----GQGSP-PEASLP--PSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEK 592
Query: 791 HMHNMMLLQQNMKQIQHNLHLGLAP----------------AEAELYQYYLAQNIGL--- 831
HM N+++L Q L LGL P + EL+QY+ Q +G
Sbjct: 593 HMQNVLMLHQ-------GLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQT 645
Query: 832 ----TGMKLENPADPQLMINPFQLDPATAAAL---APG-------------LGELS---- 867
G++ + P + QL++N F A A APG LG S
Sbjct: 646 PLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLP 705
Query: 868 ---PYISDPALKLFQCAVCNKFTSDSLEALSVHVSSERSLPEEEWRAVIGDIYQCKLCNY 924
P +LK+F+C VC F++DSLE L H S RSLPE EW+ V GD ++CKLC Y
Sbjct: 706 TSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCY 765
Query: 925 NTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKSNEWRLKCIAIG--------NPVHLKCN 976
TQLKANFQLH KTDKH QKYQL AH++EGG + ++G +P+HL+CN
Sbjct: 766 GTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPA-SLGDGAPYGSVSPLHLRCN 824
Query: 977 ACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQKQEGAVNPESCYYYCAVCDYTTKVKLNL 1036
CD+ +NS +K++LH HE ++YK + E Y+C +C + T +L +
Sbjct: 825 ICDFESNSKEKMQLHARGAAHEENSQIYK------VRLGAELGLYHCLLCAWETPSRLAV 878
Query: 1037 VQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPNELETASLGARTCDDDL 1096
+QH+R+ H+ + R+LQL Q G EE L+ + + +L T + +
Sbjct: 879 LQHLRTPAHRDAQAQRRLQLLQNGPTTEE-GLAALQSILSFSHGQLRTPA------EVVP 931
Query: 1097 TEQHEEAEGAIKPTAVAEDDEKDTSERDNSEGKNSNKDSVSVAGGTQPLLLAKEEDVATK 1156
E G I P E+ + + K K+ + ++ L T
Sbjct: 932 AEAGNSQPGTIDPEGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGSHPSLTL 991
Query: 1157 RSKPTEDNKFCHEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHL 1216
R P C Q Y CPYC++ S + S+++ H LSQH+VQP CPLCQ+ L + L
Sbjct: 992 RPLP-----ICSLQVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPAL 1046
Query: 1217 QLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKY 1275
HL+HLH+V P+CVEKLL+ V V L+ A + + G G +
Sbjct: 1047 HFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDLIRAVQEGRKRQGYSGRCMCWGQGAF 1105
Score = 270 bits (691), Expect = 1e-71
Identities = 204/641 (31%), Positives = 283/641 (44%), Gaps = 140/641 (21%)
Query: 2854 SETSSIADPSSPNPFGSSNPFKSKSN--DRPGHKRFRTQMSNLQLKVLKACFSDYRTPTM 2911
S SS+A+P SP G+S + D G +R+RTQMS+LQLK++KAC+ YRTPTM
Sbjct: 2167 SSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTM 2226
Query: 2912 QECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGT----KPECTLC 2967
QECE+LG EIGLPKRV+QVWFQNARAKEKK K+ G G +EG + +C C
Sbjct: 2227 QECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ-GTAAGSTGGSSEGLLAAQRTDCPYC 2285
Query: 2968 GVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASD 3027
VKY +S R H+FS+QH++K++E V +QL E K D
Sbjct: 2286 DVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSES---------------------KCYD 2324
Query: 3028 VLGLTVQQPGMMDSSSLHGISLPT-AYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPP 3086
+ P + + S+P A P LP L PVLL G G N+
Sbjct: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAA 2384
Query: 3087 GAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPP---------PPPPPPSSSLSGQQT 3137
+G+LG TS + + ++ P +PL Q P P P P PP+ L + +
Sbjct: 2385 SSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVS 2444
Query: 3138 EQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQ 3197
++ + + + +K +K L+ T P
Sbjct: 2445 SERKPVAGPTSSSNDALKNLKA--LKTTVP------------------------------ 2472
Query: 3198 LQALQNAIAGDPASFIGGQFLPYFIPGFASYFTPQLPGT-VQGGYFPPVCGMES-LFPYG 3255
+ +GGQFLP+ +P P + G +QG YF + GM+ LFP
Sbjct: 2473 -------------ALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMN 2519
Query: 3256 PTMPQTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQKPVQAKTSKVESDQPQNS 3315
P +PQTL GL P ALLQ Q +P K
Sbjct: 2520 PMIPQTLIGLLPNALLQP-------------------PPQPPEPTATAPPKPPELPAPGE 2560
Query: 3316 NDASETKEDKSTATESTKEEPQLESKSADFSDTYVVPFVKYEFICRKCQMMFTDEDAAVN 3375
+A E E + +T + + V + ++CR+C+M F E A
Sbjct: 2561 GEAGEVDELLTGSTGISTVD------------------VTHRYLCRQCKMAFDGEAPATA 2602
Query: 3376 HQKSFCYFGQPLIDPQETVLRVPVSKYQCLACDVAISGNEALSQHLQSSLHKEK------ 3429
HQ+SFC+FG+ LRVP+ Y CLAC+V +SG EAL+ HL+SS H+ K
Sbjct: 2603 HQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSGREALASHLRSSAHRRKAAPPQG 2662
Query: 3430 -----------TIKQAMRNAKEHVRLLPHSVCSPNPNTTST 3459
A+ AKE R LPH+ +P TTST
Sbjct: 2663 GPPISITNAATAASAAVAFAKEEAR-LPHTDSNPKTTTTST 2702
Score = 228 bits (581), Expect = 8e-59
Identities = 211/738 (28%), Positives = 285/738 (38%), Gaps = 209/738 (28%)
Query: 1955 PETPPPPPP------------PPPLPPAPPQPSSM-------------------GPVKIP 1983
P PPPPP PP LPP P P S+ GP
Sbjct: 1455 PFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL 1514
Query: 1984 NTVSTPLQAPPPTPPPPPPPPP----------PP---------PPPPPPPPPSAPPQVQL 2024
+ L P TPPPPP PP PP P PP P P+ +
Sbjct: 1515 AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAA 1574
Query: 2025 PVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLCQQQLGLDPNFL---RH 2081
L+ F ++ A+PP P +AL C L N L H
Sbjct: 1575 KALLENFGFELVIQYNEGKQAVPPPPTP--PPPEALGGGDKLACGACGKLFSNMLILKTH 1632
Query: 2082 SQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQ 2141
+ R + L Y + +AE K
Sbjct: 1633 EEHVHRRFL----PFEALSRYAAQFRKSYDSLYPPLAEPP----------------KPPD 1672
Query: 2142 RNKDSPYNFSNPPITVLEDIR-----------------IDPQPTSLEHYKSDASFSKRSS 2184
+ DSP PP V E I+ + +S + +R S
Sbjct: 1673 GSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFS 1732
Query: 2185 RTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQA 2244
RT+FT++Q + LQ FF+T+AYPKD E+E+L+++L L +RV+VVWFQNARQKARK N
Sbjct: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK---NAC 1789
Query: 2245 ETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQT 2304
E T C++C+ F +F+L+ H KK CY D+ + ++E
Sbjct: 1790 EGGSMPTGGGTGGAS--------GCRRCHATFSCVFELVRHLKK-CYDDQTLEEEEE--- 1837
Query: 2305 EDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYP 2364
E E+ + E
Sbjct: 1838 ------------------------------------------------EAERGEEEEEVE 1849
Query: 2365 AEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTP 2424
E+ ++ P G + LP + QA + G+ P TP
Sbjct: 1850 EEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAG------------GKEPEEKATP 1897
Query: 2425 VPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFL 2484
PS + CDQC ++F + +L H+ +HFL + L
Sbjct: 1898 SPSPA------------------HTCDQCAISFSSQDLLTSHRRLHFLPS----LQPSAP 1935
Query: 2485 ERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNN 2544
+ +D+P ++F NPL+ A++S P LKRK +D +
Sbjct: 1936 PQLLDLPLLVFGERNPLV---------------AATSPMPGPP-----LKRKHEDGSLSP 1975
Query: 2545 CSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVV 2604
+ GG + RDKRLRTTI PEQLEILY Y+ DSNPTRKMLD I+ EVGLKKRVV
Sbjct: 1976 TGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVV 2035
Query: 2605 QVWFQNTRARERKGQFRA 2622
QVWFQNTRARERKGQFR+
Sbjct: 2036 QVWFQNTRARERKGQFRS 2053
Score = 186 bits (473), Expect = 3e-46
Identities = 118/308 (38%), Positives = 158/308 (51%), Gaps = 65/308 (21%)
Query: 1426 AESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMGSEPKRTLPFRKGPNFT 1485
A TM++++ G E+ A P +DS + L +RK NF
Sbjct: 1275 APPPTMAEEEEGTTGELR---------SAEPAPADS-----------RHPLTYRKTTNFA 1314
Query: 1486 MEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSP------VPQET 1539
++KFLDP+RPYKCTVCKESFTQKNILLVHYNSVSHLHK+KK + S+P P T
Sbjct: 1315 LDKFLDPARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTT 1374
Query: 1540 NSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS 1599
+ TD KP+KC++C V+Y+QSSTLEIHMRSVLHQT++R K + + +
Sbjct: 1375 TAATD-KPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTD------------SKIEG 1421
Query: 1600 PGQGMLDSMSLAAVNSKDTHLDAKELNKKQTPD---LISAQPAHHPPQSPAQIQMQLQHE 1656
P + + K+ + + +K+ PD IS P PP P +
Sbjct: 1422 PERSQEE--------PKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHR----- 1468
Query: 1657 LQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGTEFSLGPDLGLPGSA- 1715
F P LP FP+ PE+LL+ QQ Q L PFY+ + +GP L L G A
Sbjct: 1469 -------FPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYL--HDLKVGPKLTLAGPAP 1519
Query: 1716 TFGMPGMT 1723
+P T
Sbjct: 1520 VLSLPAAT 1527
Score = 130 bits (328), Expect = 2e-29
Identities = 79/177 (44%), Positives = 100/177 (56%), Gaps = 12/177 (6%)
Query: 1820 PEKPKQEFISEGEGLKEGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQY 1879
P+ PK E ++E E + K+ PS PP + + A AAKALLENFGFELVIQY
Sbjct: 1532 PQPPKAE-LAEREWERPPM-AKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQY 1589
Query: 1880 NENRQKVQKKGKSGEGE---NTDKLECGTCGKLFSNVLILKSHQEHVHGQFFPYAALEKF 1936
NE +Q V E DKL CG CGKLFSN+LILK+H+EHVH +F P+ AL ++
Sbjct: 1590 NEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRY 1649
Query: 1937 ARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAP 1993
A Q+R++YD LYP P PP PP L P P P +P + +AP
Sbjct: 1650 AAQFRKSYDSLYP-----PLAEPPKPPDGSLD--SPVPHLGPPFLVPEPEAGGTRAP 1699
Score = 65.1 bits (157), Expect = 1e-09
Identities = 56/189 (29%), Positives = 82/189 (43%), Gaps = 41/189 (21%)
Query: 2515 PPQASSSHTTAPTTVAASLKR-KLDDKEDNNCSEKE----GGNSG--------EDQHRDK 2561
PP+AS P + A SL L D ++ +E E GG SG D +
Sbjct: 2147 PPKAS------PESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQR 2200
Query: 2562 RLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFR 2621
R RT ++ QL+I+ Y PT + + + E+GL KRV+QVWFQN RA+E+K + +
Sbjct: 2201 RYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ 2260
Query: 2622 AVGP-----------AQSHKRCPFCRALFKAKSALESHIRSR-HWNEGKQA--------- 2660
A CP+C + + H+ SR H + K+A
Sbjct: 2261 GTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSES 2320
Query: 2661 -GYSLPPSP 2668
Y L P+P
Sbjct: 2321 KCYDLAPAP 2329
Score = 60.1 bits (144), Expect = 4e-08
Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 18/203 (8%)
Query: 1957 TPPPPPPPPPLPPAPPQPSSM-------GPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPP 2009
TP P P PPA P+S+ G V P + P P P P P
Sbjct: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113
Query: 2010 PPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHP-ALPPQLALQLPQMDALSADLTQLC 2068
PP + P + P+ L P PS P + P A P A L D + + L
Sbjct: 2114 FLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLA 2173
Query: 2069 QQQL----------GLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMA 2118
+ + G +R RT+++ QLKI++A ++ +P+ ++ + +
Sbjct: 2174 EPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLG 2233
Query: 2119 EKSGLSQKVIKHWFRNTLFKERQ 2141
E+ GL ++VI+ WF+N KE++
Sbjct: 2234 EEIGLPKRVIQVWFQNARAKEKK 2256
Score = 57.0 bits (136), Expect = 3e-07
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 5/78 (6%)
Query: 2869 GSSNPFKSKSN-----DRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGL 2923
GS +P S++ + P KR RT + QL++L + PT + + + E+GL
Sbjct: 1971 GSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGL 2030
Query: 2924 PKRVVQVWFQNARAKEKK 2941
KRVVQVWFQN RA+E+K
Sbjct: 2031 KKRVVQVWFQNTRARERK 2048
Score = 53.1 bits (126), Expect = 5e-06
Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 11/135 (8%)
Query: 2855 ETSSIADPSSPNPFGSSNPFKSKSNDR-------PGHKRF-RTQMSNLQLKVLKACFSDY 2906
E P + G P + + + R P +RF RT+ + Q + L++ F
Sbjct: 1692 EAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETS 1751
Query: 2907 RTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGTKPECTL 2966
P E E L + +GL RVV VWFQNAR K +K G M GGT G C
Sbjct: 1752 AYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGS--MPTGGGTGGAS-GCRR 1808
Query: 2967 CGVKYSARLSIRDHI 2981
C +S + H+
Sbjct: 1809 CHATFSCVFELVRHL 1823
Score = 51.2 bits (121), Expect = 2e-05
Identities = 72/309 (23%), Positives = 116/309 (37%), Gaps = 46/309 (14%)
Query: 1875 LVIQYNENRQKVQKKGKSGE-----GENTDKLECGTCGKLFSNVLILKSHQEHVHGQFFP 1929
+V+ + RQK +K G G C C FS V L H + +
Sbjct: 1773 VVVWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTL 1832
Query: 1930 YAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTP 1989
E+ R E + + PP P P P PP + + +T
Sbjct: 1833 EEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPL--PEPPDGEELSQAE-----ATK 1885
Query: 1990 LQAPPPTPPPPPPPPPPPPPPP--------------------PPPPPSAPPQVQLPVSLD 2029
P P P P P PSAPPQ+ LD
Sbjct: 1886 AGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQL-----LD 1940
Query: 2030 LPLFPSIMMQPVQHPALP-PQLALQLPQMD-ALSADLTQLCQQQLGLDPNFLRHSQFKRP 2087
LPL P+ P P L+ D +LS ++ G P + KR
Sbjct: 1941 LPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPP------RDKRL 1994
Query: 2088 RTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQ-RNKDS 2146
RT I +QL+IL ++ +++P+ + + ++E+ GL ++V++ WF+NT +ER+ + + +
Sbjct: 1995 RTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRST 2054
Query: 2147 PYNFSNPPI 2155
P +P +
Sbjct: 2055 PGGVPSPAV 2063
Score = 50.1 bits (118), Expect = 4e-05
Identities = 92/450 (20%), Positives = 146/450 (32%), Gaps = 73/450 (16%)
Query: 2267 YQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTD 2326
++C C V + + L H + ++ + +S+ E + ++ K G+
Sbjct: 1382 FKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEP--KEGETEGEVG 1439
Query: 2327 AAKNAAAPAASSGSGTSTPLIPSPKPE------------PEKTSPKPEYPAEKPKQSD-- 2372
K +SG + P + P P P P P P K
Sbjct: 1440 TEKKGPD---TSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQ 1496
Query: 2373 -------------PSPPSQGTKPALPL-ASTSSDPPQASTAQ--PQPQPQPPKQPQLIGR 2416
P G P L L A+T PPQ A+ + +PP +
Sbjct: 1497 LLLPFYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEA 1556
Query: 2417 PPSASQTPVPSSPLQISMTSLQNSL----------------------PPQLL----QYQC 2450
PS+ P+P+ + + +L + PP+ L + C
Sbjct: 1557 GPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLAC 1616
Query: 2451 DQCTVAFPT---LELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYM-IFDPNNPLMTGQL 2506
C F L+ +EH H FL + ++ + D Y + +P P
Sbjct: 1617 GACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKP--PDGS 1674
Query: 2507 LGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRL-RT 2565
L S + + P A T A + + E GN +R RT
Sbjct: 1675 LDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRT 1734
Query: 2566 TITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERK-----GQF 2620
T Q + L + + P ++ +A +GL RVV VWFQN R + RK G
Sbjct: 1735 KFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSM 1794
Query: 2621 RAVGPAQSHKRCPFCRALFKAKSALESHIR 2650
G C C A F L H++
Sbjct: 1795 PTGGGTGGASGCRRCHATFSCVFELVRHLK 1824
Score = 49.3 bits (116), Expect = 7e-05
Identities = 88/377 (23%), Positives = 141/377 (37%), Gaps = 57/377 (15%)
Query: 2181 KRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSY 2240
+R RT+ + QL++++ ++ P E E L + LP RVI VWFQNAR K
Sbjct: 2199 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAK----- 2253
Query: 2241 ENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQD 2300
E +A+ + + + C C+V + H + Q
Sbjct: 2254 EKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSR---------QH 2304
Query: 2301 ESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPS-PKPEPEKTS- 2358
++ ++++ A + K ++ +A AP A++ + P+ P+ P S
Sbjct: 2305 LAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSG 2364
Query: 2359 ---PKPEYPAEKPKQSDPSPPS----------------QGTKPALPLAS-TSSDPPQAST 2398
+P P S P+ S Q P PL D ST
Sbjct: 2365 PALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTST 2424
Query: 2399 A-QPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQN-----SLPPQLLQYQCDQ 2452
A P P PP +P +G S+ + PV + P S +L+N + P LL Q
Sbjct: 2425 AGTTDPVPGPPTEP--LGDKVSSERKPV-AGPTSSSNDALKNLKALKTTVPALLGGQ--- 2478
Query: 2453 CTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLG---S 2509
+ FP F L + ++ M +F P NP++ L+G +
Sbjct: 2479 -FLPFPLPPAGGTAPPAVF----GPQLQGAYFQQLYGMKKGLF-PMNPMIPQTLIGLLPN 2532
Query: 2510 SLTQMPPQASSSHTTAP 2526
+L Q PPQ TAP
Sbjct: 2533 ALLQPPPQPPEPTATAP 2549
Score = 47.4 bits (111), Expect = 3e-04
Identities = 47/189 (24%), Positives = 71/189 (37%), Gaps = 23/189 (12%)
Query: 697 KPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGNGEQVFGHSAPAPNTSLSGCGTP 756
+P++C VC S T K L +H S HL+ ++ G + P T T
Sbjct: 1323 RPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTT------TA 1376
Query: 757 SPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLAPA 816
+ KP ++C VC N + L IHM S H + + K I+ P
Sbjct: 1377 ATDKP-----FKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSK-IEGPERSQEEPK 1430
Query: 817 EAELYQYYLAQNIG------LTGMKLENPADPQLMINPFQLDPATAAALAPGLGELSPYI 870
E E + G ++G+ +P P L ++ F T L P P +
Sbjct: 1431 EGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPP-----FPLV 1485
Query: 871 SDPALKLFQ 879
+ LKL Q
Sbjct: 1486 PESLLKLQQ 1494
Score = 46.6 bits (109), Expect = 4e-04
Identities = 71/323 (21%), Positives = 107/323 (33%), Gaps = 41/323 (12%)
Query: 1433 QDDHGLEQEMEREYEVDHEGKA--SPVGS--DSSSIP------DDMGSEPKRTLPFRKGP 1482
++D GL + + EG +PVGS D S P DD P
Sbjct: 380 EEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYRLADDYTPAPAAFQGLSLSS 439
Query: 1483 NFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSV---SHLHKLKKVLQEASSPVPQET 1539
+ ++ + + KC C + + L VH S+ H A + +
Sbjct: 440 HMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGE 499
Query: 1540 NSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS 1599
+ N KPY+C +CN + + L IHM+S H + + P G + +
Sbjct: 500 SYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAG 559
Query: 1600 PGQGMLDSMSLAAVNSKDTHLDAKELNKKQT--------------------PDLISAQPA 1639
+ S V S +T++ ++ L T P L+ P
Sbjct: 560 DKEPKTKSSWQCKVCSYETNI-SRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPP 618
Query: 1640 HHPPQSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALL----QFQQPQFLFP 1695
P +P Q+ Q Q P P P+ + LL P FP
Sbjct: 619 PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFP 678
Query: 1696 FYIPGTEFSLGPDLGLPGSATFG 1718
PG SL PD LP S G
Sbjct: 679 TSAPG---SLSPDAHLPPSQLLG 698
Score = 45.4 bits (106), Expect = 0.001
Identities = 60/226 (26%), Positives = 88/226 (38%), Gaps = 29/226 (12%)
Query: 2938 KEKKFKINIGKPFMINQGGTEGT-----KP-ECTLCGVKYSARLSIRDHIFSKQHISKVR 2991
K KK I+ P G T KP +CT+C V Y+ ++ H+ S H ++ R
Sbjct: 1352 KMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSR 1411
Query: 2992 ET-VGSQLDR-EKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISL 3049
T S+++ E+ P ++ + E+ KK D G S L +S
Sbjct: 1412 GTKTDSKIEGPERSQEEP---KEGETEGEVGTEKKGPDTSGFI---------SGLPFLSP 1459
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPT---SATSSPALSLS 3106
P L P L P LP FP +L L P P L+L
Sbjct: 1460 PPPPLDLHRFPAPLFT----PPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL- 1514
Query: 3107 SAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPN 3152
A P+L P PPPPP PP + L+ ++ E+ E + P+
Sbjct: 1515 -AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPS 1559
Score = 35.8 bits (81), Expect = 0.78
Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 10/65 (15%)
Query: 1954 SPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPP 2013
+PE P P P PPL V++P+ S PP P P P P P
Sbjct: 1227 TPEASPDPLPEPPL----------ASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAP 1276
Query: 2014 PPPSA 2018
PP A
Sbjct: 1277 PPTMA 1281
Score = 35.8 bits (81), Expect = 0.78
Identities = 27/95 (28%), Positives = 31/95 (32%), Gaps = 31/95 (32%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPP------ 2002
P+ TPPPPP PP A + K N +A P +PP P P
Sbjct: 1519 PVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGN------EAGPSSPPDPLPNEAART 1572
Query: 2003 -------------------PPPPPPPPPPPPPPSA 2018
PPPP PPPP A
Sbjct: 1573 AAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEA 1607
Score = 35.4 bits (80), Expect = 1.0
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 10/69 (14%)
Query: 1989 PLQAPPPTPPPPPPPPPPPPPPPPPP-----PPSAPPQVQLPVS-----LDLPLFPSIMM 2038
PL PP P PPPPP P PP P A Q Q P++ D PL +++
Sbjct: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664
Query: 2039 QPVQHPALP 2047
H P
Sbjct: 665 NGFHHVGAP 673
Score = 35.4 bits (80), Expect = 1.0
Identities = 59/266 (22%), Positives = 102/266 (38%), Gaps = 43/266 (16%)
Query: 1759 QATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISE 1818
+AT P +P PPPP +++ + E S C + S A ++E
Sbjct: 2120 EATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPE-----SEACSLSAGDLSDSSASSLAE 2174
Query: 1819 KPEKPKQEFISEGEG----LKEGKDTKKQKSLEPSIPPPRIASGARG------NAAKALL 1868
PE P S G G + +G ++ ++ S+ + + + L
Sbjct: 2175 -PESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLG 2233
Query: 1869 ENFGF-ELVIQ-YNENRQKVQKKGK---------SGEGEN---TDKLECGTCGKLFSNVL 1914
E G + VIQ + +N + +KK K G E + +C C + +
Sbjct: 2234 EEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYV 2293
Query: 1915 ILKSH---QEHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPP-PPPPPPLPPA 1970
+ H ++H+ A L++ R ++ K Y ++P+ PE PP PP P +
Sbjct: 2294 SCRGHLFSRQHL-------AKLKEAVRAQLKSESKCYDLAPA-PEAPPALKAPPATTPAS 2345
Query: 1971 PPQPSSMG-PVKIPNTVSTPLQAPPP 1995
P ++ P P +S P A PP
Sbjct: 2346 MPLGAAPTLPRLAPVLLSGPALAQPP 2371
Score = 35.0 bits (79), Expect = 1.3
Identities = 48/199 (24%), Positives = 71/199 (35%), Gaps = 21/199 (10%)
Query: 3029 LGLTVQQPGMMDSSSLHGISL-PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPG 3087
LG + Q MD + HG+ L P Y GL G P VL G G +L F + P
Sbjct: 244 LGFSKPQ-AFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARPSS 302
Query: 3088 AGMLGFPTSATSSPALSLSSAPTKP----------LLQTPPPPPPPPPPPPSSSLSGQQT 3137
P +S+ + + A T+ +L PP PP+++ T
Sbjct: 303 ----DIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPT 358
Query: 3138 EQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVG--ETHVDP 3195
+ + + P+ + +EE+ P K L VG E DP
Sbjct: 359 QAKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPA---PVGSPEDPSDP 415
Query: 3196 IQLQALQNAIAGDPASFIG 3214
Q L + PA+F G
Sbjct: 416 PQPYRLADDYTPAPAAFQG 434
Score = 34.7 bits (78), Expect = 1.7
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 279 MCFLCKLSFGYIRSFVTHAVHDHRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEP 338
+C LC+L F ++F+ H H + L + + LS A++Q + + LISFLEP
Sbjct: 238 LCLLCRLGFSKPQAFMDH-TQSHGVKLTPAQYQGLSGS--PAVLQEGDEGCKALISFLEP 294
Query: 339 K 339
K
Sbjct: 295 K 295
Score = 34.7 bits (78), Expect = 1.7
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 8/51 (15%)
Query: 1977 MGPVKIPNTVSTPLQAPPPTPPPP------PPPPPPPPPPPPPPPPSAPPQ 2021
+ P++ PN TP +P P P PP P P P PP P PS P+
Sbjct: 1218 LSPLEGPNL--TPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPE 1266
Score = 34.7 bits (78), Expect = 1.7
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 26/79 (32%)
Query: 1925 GQFFPY--------AALEKFARQYREAYDK--------LYPISPSSPET----------P 1958
GQF P+ A F Q + AY + L+P++P P+T
Sbjct: 2477 GQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQ 2536
Query: 1959 PPPPPPPPLPPAPPQPSSM 1977
PPP PP P APP+P +
Sbjct: 2537 PPPQPPEPTATAPPKPPEL 2555
Score = 34.3 bits (77), Expect = 2.3
Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 21/107 (19%)
Query: 3054 PGLPGLPPVLLPGMNGPSSLPGFP------QNSNTLTPPGAGMLGFPTSATSSPALSLSS 3107
PG P V P P+SLP F + P FP P +L+S
Sbjct: 2055 PGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPY-----PTATLAS 2109
Query: 3108 APTKPLLQ-----TPPPPPPP----PPPPPSSSLSGQQTEQQNKESE 3145
P +P L T P P PP PPPPPS ++ + + ESE
Sbjct: 2110 GP-QPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESE 2155
Score = 33.9 bits (76), Expect = 3.0
Identities = 49/250 (19%), Positives = 90/250 (36%), Gaps = 26/250 (10%)
Query: 1173 QCPYCNYNSRDQSRIQMHVL-SQHSVQPVIC------------CPLCQDVLSNKMHLQLH 1219
+C C++ S + ++Q+H + H I C LC +++ + H
Sbjct: 822 RCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQH 881
Query: 1220 LTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKYSGES 1279
L +L + P + L + + TPA V +G + +
Sbjct: 882 LRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAG--NSQP 939
Query: 1280 PMDDKSMAGLEDSKANVEVKNEEQKPTKEPLEVSEWNKNSSKDVKIPDTLQDQLNEQQKR 1339
D G E ++ + +++K K+ EW + S+ + D +
Sbjct: 940 GTIDPEGTGEEPARGCQRLHLKKKKKKKK-----EWGRASAASKGLCD---GGSHPSLTL 991
Query: 1340 QPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHS-QYHAIRAATMCNLCQRSFRTFQALKKH 1398
+PL + VY C +CS +++ H+ HA++ C LCQ AL H
Sbjct: 992 RPLPICSLQVYC--CPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFH 1049
Query: 1399 LEAGHPELSE 1408
L H + E
Sbjct: 1050 LSHLHNVVPE 1059
Score = 33.5 bits (75), Expect = 3.9
Identities = 15/38 (39%), Positives = 17/38 (44%)
Query: 1977 MGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPP 2014
M P + + L PPP PP P PP PP P P
Sbjct: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAP 2558
Score = 32.7 bits (73), Expect = 6.6
Identities = 14/34 (41%), Positives = 16/34 (47%)
Query: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIP 1983
+ P T P P PP PL P PP GP + P
Sbjct: 2115 LPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPP 2148
Score = 32.3 bits (72), Expect = 8.6
Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 23/147 (15%)
Query: 1343 SVSDRHVYKYRCNHCSLAFKTMQKLQIH---------SQYHAIRAAT-----MCNLCQRS 1388
SVS H+ RCN C + +K+Q+H SQ + +R C LC
Sbjct: 815 SVSPLHL---RCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWE 871
Query: 1389 FRTFQALKKHLEA-GHPELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYE 1447
+ A+ +HL H + QL + P E A +++ HG + E
Sbjct: 872 TPSRLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHG-QLRTPAEVV 930
Query: 1448 VDHEGKASPVGSDSSSIPDDMGSEPKR 1474
G + P D P+ G EP R
Sbjct: 931 PAEAGNSQPGTID----PEGTGEEPAR 953
Score = 32.3 bits (72), Expect = 8.6
Identities = 23/75 (30%), Positives = 25/75 (33%), Gaps = 16/75 (21%)
Query: 1959 PPPPPPPPLPPAPPQPSSMGPV----------------KIPNTVSTPLQAPPPTPPPPPP 2002
P PP PPA P G IP T+ L PPP PP
Sbjct: 2483 PLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPP 2542
Query: 2003 PPPPPPPPPPPPPPS 2017
P PP PP P+
Sbjct: 2543 EPTATAPPKPPELPA 2557
>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 500 bits (1288), Expect = e-141
Identities = 303/779 (38%), Positives = 403/779 (51%), Gaps = 98/779 (12%)
Query: 562 ASASKDSATAAHPSEIARGDED----------SSATPHQHGFTPSTPGTP-GPGGDGSPG 610
A S +A A P G E+ SS T + G P+ G+P P P
Sbjct: 360 AKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPY 419
Query: 611 SGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP 670
+ SL HM+++HSRNSCKTLKCPKCNWHYKYQQTL+ HM+EKHPE
Sbjct: 420 RLADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPES 479
Query: 671 GGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNL 730
C YC G HPRLARGESY CGYKP+RC+VCNYSTTTKGNLSIHMQSDKHL N+Q
Sbjct: 480 NSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGF 539
Query: 731 QNGNGEQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEK 790
Q G G G +P P SL + +PK K +W+C+VC YETN++RNLRIHMTSEK
Sbjct: 540 QAGPG----GQGSP-PEASLP--PSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEK 592
Query: 791 HMHNMMLLQQNMKQIQHNLHLGLAP----------------AEAELYQYYLAQNIGL--- 831
HM N+++L Q L LGL P + EL+QY+ Q +G
Sbjct: 593 HMQNVLMLHQ-------GLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQT 645
Query: 832 ----TGMKLENPADPQLMINPFQLDPATAAAL---APG-------------LGELS---- 867
G++ + P + QL++N F A A APG LG S
Sbjct: 646 PLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLP 705
Query: 868 ---PYISDPALKLFQCAVCNKFTSDSLEALSVHVSSERSLPEEEWRAVIGDIYQCKLCNY 924
P +LK+F+C VC F++DSLE L H S RSLPE EW+ V GD ++CKLC Y
Sbjct: 706 TSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCY 765
Query: 925 NTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKSNEWRLKCIAIG--------NPVHLKCN 976
TQLKANFQLH KTDKH QKYQL AH++EGG + ++G +P+HL+CN
Sbjct: 766 GTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPA-SLGDGAPYGSVSPLHLRCN 824
Query: 977 ACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQKQEGAVNPESCYYYCAVCDYTTKVKLNL 1036
CD+ +NS +K++LH HE ++YK + E Y+C +C + T +L +
Sbjct: 825 ICDFESNSKEKMQLHARGAAHEENSQIYK------VRLGAELGLYHCLLCAWETPSRLAV 878
Query: 1037 VQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPNELETASLGARTCDDDL 1096
+QH+R+ H+ + R+LQL Q G EE L+ + + +L T + +
Sbjct: 879 LQHLRTPAHRDAQAQRRLQLLQNGPTTEE-GLAALQSILSFSHGQLRTPA------EVVP 931
Query: 1097 TEQHEEAEGAIKPTAVAEDDEKDTSERDNSEGKNSNKDSVSVAGGTQPLLLAKEEDVATK 1156
E G I P E+ + + K K+ + ++ L T
Sbjct: 932 AEAGNSQPGTIDPEGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGSHPSLTL 991
Query: 1157 RSKPTEDNKFCHEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHL 1216
R P C Q Y CPYC++ S + S+++ H LSQH+VQP CPLCQ+ L + L
Sbjct: 992 RPLP-----ICSLQVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPAL 1046
Query: 1217 QLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKY 1275
HL+HLH+V P+CVEKLL+ V V L+ A + + G G +
Sbjct: 1047 HFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDLIRAVQEGRKRQGYSGRCMCWGQGAF 1105
Score = 270 bits (691), Expect = 1e-71
Identities = 204/641 (31%), Positives = 283/641 (44%), Gaps = 140/641 (21%)
Query: 2854 SETSSIADPSSPNPFGSSNPFKSKSN--DRPGHKRFRTQMSNLQLKVLKACFSDYRTPTM 2911
S SS+A+P SP G+S + D G +R+RTQMS+LQLK++KAC+ YRTPTM
Sbjct: 2167 SSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTM 2226
Query: 2912 QECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGT----KPECTLC 2967
QECE+LG EIGLPKRV+QVWFQNARAKEKK K+ G G +EG + +C C
Sbjct: 2227 QECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ-GTAAGSTGGSSEGLLAAQRTDCPYC 2285
Query: 2968 GVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASD 3027
VKY +S R H+FS+QH++K++E V +QL E K D
Sbjct: 2286 DVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSES---------------------KCYD 2324
Query: 3028 VLGLTVQQPGMMDSSSLHGISLPT-AYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPP 3086
+ P + + S+P A P LP L PVLL G G N+
Sbjct: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAA 2384
Query: 3087 GAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPP---------PPPPPPSSSLSGQQT 3137
+G+LG TS + + ++ P +PL Q P P P P PP+ L + +
Sbjct: 2385 SSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVS 2444
Query: 3138 EQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQ 3197
++ + + + +K +K L+ T P
Sbjct: 2445 SERKPVAGPTSSSNDALKNLKA--LKTTVP------------------------------ 2472
Query: 3198 LQALQNAIAGDPASFIGGQFLPYFIPGFASYFTPQLPGT-VQGGYFPPVCGMES-LFPYG 3255
+ +GGQFLP+ +P P + G +QG YF + GM+ LFP
Sbjct: 2473 -------------ALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMN 2519
Query: 3256 PTMPQTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQKPVQAKTSKVESDQPQNS 3315
P +PQTL GL P ALLQ Q +P K
Sbjct: 2520 PMIPQTLIGLLPNALLQP-------------------PPQPPEPTATAPPKPPELPAPGE 2560
Query: 3316 NDASETKEDKSTATESTKEEPQLESKSADFSDTYVVPFVKYEFICRKCQMMFTDEDAAVN 3375
+A E E + +T + + V + ++CR+C+M F E A
Sbjct: 2561 GEAGEVDELLTGSTGISTVD------------------VTHRYLCRQCKMAFDGEAPATA 2602
Query: 3376 HQKSFCYFGQPLIDPQETVLRVPVSKYQCLACDVAISGNEALSQHLQSSLHKEK------ 3429
HQ+SFC+FG+ LRVP+ Y CLAC+V +SG EAL+ HL+SS H+ K
Sbjct: 2603 HQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSGREALASHLRSSAHRRKAAPPQG 2662
Query: 3430 -----------TIKQAMRNAKEHVRLLPHSVCSPNPNTTST 3459
A+ AKE R LPH+ +P TTST
Sbjct: 2663 GPPISITNAATAASAAVAFAKEEAR-LPHTDSNPKTTTTST 2702
Score = 228 bits (581), Expect = 8e-59
Identities = 211/738 (28%), Positives = 285/738 (38%), Gaps = 209/738 (28%)
Query: 1955 PETPPPPPP------------PPPLPPAPPQPSSM-------------------GPVKIP 1983
P PPPPP PP LPP P P S+ GP
Sbjct: 1455 PFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL 1514
Query: 1984 NTVSTPLQAPPPTPPPPPPPPP----------PP---------PPPPPPPPPSAPPQVQL 2024
+ L P TPPPPP PP PP P PP P P+ +
Sbjct: 1515 AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAA 1574
Query: 2025 PVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLCQQQLGLDPNFL---RH 2081
L+ F ++ A+PP P +AL C L N L H
Sbjct: 1575 KALLENFGFELVIQYNEGKQAVPPPPTP--PPPEALGGGDKLACGACGKLFSNMLILKTH 1632
Query: 2082 SQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQ 2141
+ R + L Y + +AE K
Sbjct: 1633 EEHVHRRFL----PFEALSRYAAQFRKSYDSLYPPLAEPP----------------KPPD 1672
Query: 2142 RNKDSPYNFSNPPITVLEDIR-----------------IDPQPTSLEHYKSDASFSKRSS 2184
+ DSP PP V E I+ + +S + +R S
Sbjct: 1673 GSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFS 1732
Query: 2185 RTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQA 2244
RT+FT++Q + LQ FF+T+AYPKD E+E+L+++L L +RV+VVWFQNARQKARK N
Sbjct: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK---NAC 1789
Query: 2245 ETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQT 2304
E T C++C+ F +F+L+ H KK CY D+ + ++E
Sbjct: 1790 EGGSMPTGGGTGGAS--------GCRRCHATFSCVFELVRHLKK-CYDDQTLEEEEE--- 1837
Query: 2305 EDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYP 2364
E E+ + E
Sbjct: 1838 ------------------------------------------------EAERGEEEEEVE 1849
Query: 2365 AEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTP 2424
E+ ++ P G + LP + QA + G+ P TP
Sbjct: 1850 EEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAG------------GKEPEEKATP 1897
Query: 2425 VPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFL 2484
PS + CDQC ++F + +L H+ +HFL + L
Sbjct: 1898 SPSPA------------------HTCDQCAISFSSQDLLTSHRRLHFLPS----LQPSAP 1935
Query: 2485 ERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNN 2544
+ +D+P ++F NPL+ A++S P LKRK +D +
Sbjct: 1936 PQLLDLPLLVFGERNPLV---------------AATSPMPGPP-----LKRKHEDGSLSP 1975
Query: 2545 CSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVV 2604
+ GG + RDKRLRTTI PEQLEILY Y+ DSNPTRKMLD I+ EVGLKKRVV
Sbjct: 1976 TGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVV 2035
Query: 2605 QVWFQNTRARERKGQFRA 2622
QVWFQNTRARERKGQFR+
Sbjct: 2036 QVWFQNTRARERKGQFRS 2053
Score = 186 bits (473), Expect = 3e-46
Identities = 118/308 (38%), Positives = 158/308 (51%), Gaps = 65/308 (21%)
Query: 1426 AESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMGSEPKRTLPFRKGPNFT 1485
A TM++++ G E+ A P +DS + L +RK NF
Sbjct: 1275 APPPTMAEEEEGTTGELR---------SAEPAPADS-----------RHPLTYRKTTNFA 1314
Query: 1486 MEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSP------VPQET 1539
++KFLDP+RPYKCTVCKESFTQKNILLVHYNSVSHLHK+KK + S+P P T
Sbjct: 1315 LDKFLDPARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTT 1374
Query: 1540 NSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS 1599
+ TD KP+KC++C V+Y+QSSTLEIHMRSVLHQT++R K + + +
Sbjct: 1375 TAATD-KPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTD------------SKIEG 1421
Query: 1600 PGQGMLDSMSLAAVNSKDTHLDAKELNKKQTPD---LISAQPAHHPPQSPAQIQMQLQHE 1656
P + + K+ + + +K+ PD IS P PP P +
Sbjct: 1422 PERSQEE--------PKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHR----- 1468
Query: 1657 LQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGTEFSLGPDLGLPGSA- 1715
F P LP FP+ PE+LL+ QQ Q L PFY+ + +GP L L G A
Sbjct: 1469 -------FPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYL--HDLKVGPKLTLAGPAP 1519
Query: 1716 TFGMPGMT 1723
+P T
Sbjct: 1520 VLSLPAAT 1527
Score = 130 bits (328), Expect = 2e-29
Identities = 79/177 (44%), Positives = 100/177 (56%), Gaps = 12/177 (6%)
Query: 1820 PEKPKQEFISEGEGLKEGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQY 1879
P+ PK E ++E E + K+ PS PP + + A AAKALLENFGFELVIQY
Sbjct: 1532 PQPPKAE-LAEREWERPPM-AKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQY 1589
Query: 1880 NENRQKVQKKGKSGEGE---NTDKLECGTCGKLFSNVLILKSHQEHVHGQFFPYAALEKF 1936
NE +Q V E DKL CG CGKLFSN+LILK+H+EHVH +F P+ AL ++
Sbjct: 1590 NEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRY 1649
Query: 1937 ARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAP 1993
A Q+R++YD LYP P PP PP L P P P +P + +AP
Sbjct: 1650 AAQFRKSYDSLYP-----PLAEPPKPPDGSLD--SPVPHLGPPFLVPEPEAGGTRAP 1699
Score = 65.1 bits (157), Expect = 1e-09
Identities = 56/189 (29%), Positives = 82/189 (43%), Gaps = 41/189 (21%)
Query: 2515 PPQASSSHTTAPTTVAASLKR-KLDDKEDNNCSEKE----GGNSG--------EDQHRDK 2561
PP+AS P + A SL L D ++ +E E GG SG D +
Sbjct: 2147 PPKAS------PESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQR 2200
Query: 2562 RLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFR 2621
R RT ++ QL+I+ Y PT + + + E+GL KRV+QVWFQN RA+E+K + +
Sbjct: 2201 RYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ 2260
Query: 2622 AVGP-----------AQSHKRCPFCRALFKAKSALESHIRSR-HWNEGKQA--------- 2660
A CP+C + + H+ SR H + K+A
Sbjct: 2261 GTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSES 2320
Query: 2661 -GYSLPPSP 2668
Y L P+P
Sbjct: 2321 KCYDLAPAP 2329
Score = 60.1 bits (144), Expect = 4e-08
Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 18/203 (8%)
Query: 1957 TPPPPPPPPPLPPAPPQPSSM-------GPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPP 2009
TP P P PPA P+S+ G V P + P P P P P
Sbjct: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113
Query: 2010 PPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHP-ALPPQLALQLPQMDALSADLTQLC 2068
PP + P + P+ L P PS P + P A P A L D + + L
Sbjct: 2114 FLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLA 2173
Query: 2069 QQQL----------GLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMA 2118
+ + G +R RT+++ QLKI++A ++ +P+ ++ + +
Sbjct: 2174 EPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLG 2233
Query: 2119 EKSGLSQKVIKHWFRNTLFKERQ 2141
E+ GL ++VI+ WF+N KE++
Sbjct: 2234 EEIGLPKRVIQVWFQNARAKEKK 2256
Score = 57.0 bits (136), Expect = 3e-07
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 5/78 (6%)
Query: 2869 GSSNPFKSKSN-----DRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGL 2923
GS +P S++ + P KR RT + QL++L + PT + + + E+GL
Sbjct: 1971 GSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGL 2030
Query: 2924 PKRVVQVWFQNARAKEKK 2941
KRVVQVWFQN RA+E+K
Sbjct: 2031 KKRVVQVWFQNTRARERK 2048
Score = 53.1 bits (126), Expect = 5e-06
Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 11/135 (8%)
Query: 2855 ETSSIADPSSPNPFGSSNPFKSKSNDR-------PGHKRF-RTQMSNLQLKVLKACFSDY 2906
E P + G P + + + R P +RF RT+ + Q + L++ F
Sbjct: 1692 EAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETS 1751
Query: 2907 RTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGTKPECTL 2966
P E E L + +GL RVV VWFQNAR K +K G M GGT G C
Sbjct: 1752 AYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGS--MPTGGGTGGAS-GCRR 1808
Query: 2967 CGVKYSARLSIRDHI 2981
C +S + H+
Sbjct: 1809 CHATFSCVFELVRHL 1823
Score = 51.2 bits (121), Expect = 2e-05
Identities = 72/309 (23%), Positives = 116/309 (37%), Gaps = 46/309 (14%)
Query: 1875 LVIQYNENRQKVQKKGKSGE-----GENTDKLECGTCGKLFSNVLILKSHQEHVHGQFFP 1929
+V+ + RQK +K G G C C FS V L H + +
Sbjct: 1773 VVVWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTL 1832
Query: 1930 YAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTP 1989
E+ R E + + PP P P P PP + + +T
Sbjct: 1833 EEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPL--PEPPDGEELSQAE-----ATK 1885
Query: 1990 LQAPPPTPPPPPPPPPPPPPPP--------------------PPPPPSAPPQVQLPVSLD 2029
P P P P P PSAPPQ+ LD
Sbjct: 1886 AGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQL-----LD 1940
Query: 2030 LPLFPSIMMQPVQHPALP-PQLALQLPQMD-ALSADLTQLCQQQLGLDPNFLRHSQFKRP 2087
LPL P+ P P L+ D +LS ++ G P + KR
Sbjct: 1941 LPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPP------RDKRL 1994
Query: 2088 RTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQ-RNKDS 2146
RT I +QL+IL ++ +++P+ + + ++E+ GL ++V++ WF+NT +ER+ + + +
Sbjct: 1995 RTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRST 2054
Query: 2147 PYNFSNPPI 2155
P +P +
Sbjct: 2055 PGGVPSPAV 2063
Score = 50.1 bits (118), Expect = 4e-05
Identities = 92/450 (20%), Positives = 146/450 (32%), Gaps = 73/450 (16%)
Query: 2267 YQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTD 2326
++C C V + + L H + ++ + +S+ E + ++ K G+
Sbjct: 1382 FKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEP--KEGETEGEVG 1439
Query: 2327 AAKNAAAPAASSGSGTSTPLIPSPKPE------------PEKTSPKPEYPAEKPKQSD-- 2372
K +SG + P + P P P P P P K
Sbjct: 1440 TEKKGPD---TSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQ 1496
Query: 2373 -------------PSPPSQGTKPALPL-ASTSSDPPQASTAQ--PQPQPQPPKQPQLIGR 2416
P G P L L A+T PPQ A+ + +PP +
Sbjct: 1497 LLLPFYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEA 1556
Query: 2417 PPSASQTPVPSSPLQISMTSLQNSL----------------------PPQLL----QYQC 2450
PS+ P+P+ + + +L + PP+ L + C
Sbjct: 1557 GPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLAC 1616
Query: 2451 DQCTVAFPT---LELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYM-IFDPNNPLMTGQL 2506
C F L+ +EH H FL + ++ + D Y + +P P
Sbjct: 1617 GACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKP--PDGS 1674
Query: 2507 LGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRL-RT 2565
L S + + P A T A + + E GN +R RT
Sbjct: 1675 LDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRT 1734
Query: 2566 TITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERK-----GQF 2620
T Q + L + + P ++ +A +GL RVV VWFQN R + RK G
Sbjct: 1735 KFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSM 1794
Query: 2621 RAVGPAQSHKRCPFCRALFKAKSALESHIR 2650
G C C A F L H++
Sbjct: 1795 PTGGGTGGASGCRRCHATFSCVFELVRHLK 1824
Score = 49.3 bits (116), Expect = 7e-05
Identities = 88/377 (23%), Positives = 141/377 (37%), Gaps = 57/377 (15%)
Query: 2181 KRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSY 2240
+R RT+ + QL++++ ++ P E E L + LP RVI VWFQNAR K
Sbjct: 2199 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAK----- 2253
Query: 2241 ENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQD 2300
E +A+ + + + C C+V + H + Q
Sbjct: 2254 EKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSR---------QH 2304
Query: 2301 ESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPS-PKPEPEKTS- 2358
++ ++++ A + K ++ +A AP A++ + P+ P+ P S
Sbjct: 2305 LAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSG 2364
Query: 2359 ---PKPEYPAEKPKQSDPSPPS----------------QGTKPALPLAS-TSSDPPQAST 2398
+P P S P+ S Q P PL D ST
Sbjct: 2365 PALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTST 2424
Query: 2399 A-QPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQN-----SLPPQLLQYQCDQ 2452
A P P PP +P +G S+ + PV + P S +L+N + P LL Q
Sbjct: 2425 AGTTDPVPGPPTEP--LGDKVSSERKPV-AGPTSSSNDALKNLKALKTTVPALLGGQ--- 2478
Query: 2453 CTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLG---S 2509
+ FP F L + ++ M +F P NP++ L+G +
Sbjct: 2479 -FLPFPLPPAGGTAPPAVF----GPQLQGAYFQQLYGMKKGLF-PMNPMIPQTLIGLLPN 2532
Query: 2510 SLTQMPPQASSSHTTAP 2526
+L Q PPQ TAP
Sbjct: 2533 ALLQPPPQPPEPTATAP 2549
Score = 47.4 bits (111), Expect = 3e-04
Identities = 47/189 (24%), Positives = 71/189 (37%), Gaps = 23/189 (12%)
Query: 697 KPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGNGEQVFGHSAPAPNTSLSGCGTP 756
+P++C VC S T K L +H S HL+ ++ G + P T T
Sbjct: 1323 RPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTT------TA 1376
Query: 757 SPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLAPA 816
+ KP ++C VC N + L IHM S H + + K I+ P
Sbjct: 1377 ATDKP-----FKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSK-IEGPERSQEEPK 1430
Query: 817 EAELYQYYLAQNIG------LTGMKLENPADPQLMINPFQLDPATAAALAPGLGELSPYI 870
E E + G ++G+ +P P L ++ F T L P P +
Sbjct: 1431 EGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPP-----FPLV 1485
Query: 871 SDPALKLFQ 879
+ LKL Q
Sbjct: 1486 PESLLKLQQ 1494
Score = 46.6 bits (109), Expect = 4e-04
Identities = 71/323 (21%), Positives = 107/323 (33%), Gaps = 41/323 (12%)
Query: 1433 QDDHGLEQEMEREYEVDHEGKA--SPVGS--DSSSIP------DDMGSEPKRTLPFRKGP 1482
++D GL + + EG +PVGS D S P DD P
Sbjct: 380 EEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYRLADDYTPAPAAFQGLSLSS 439
Query: 1483 NFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSV---SHLHKLKKVLQEASSPVPQET 1539
+ ++ + + KC C + + L VH S+ H A + +
Sbjct: 440 HMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGE 499
Query: 1540 NSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS 1599
+ N KPY+C +CN + + L IHM+S H + + P G + +
Sbjct: 500 SYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAG 559
Query: 1600 PGQGMLDSMSLAAVNSKDTHLDAKELNKKQT--------------------PDLISAQPA 1639
+ S V S +T++ ++ L T P L+ P
Sbjct: 560 DKEPKTKSSWQCKVCSYETNI-SRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPP 618
Query: 1640 HHPPQSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALL----QFQQPQFLFP 1695
P +P Q+ Q Q P P P+ + LL P FP
Sbjct: 619 PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFP 678
Query: 1696 FYIPGTEFSLGPDLGLPGSATFG 1718
PG SL PD LP S G
Sbjct: 679 TSAPG---SLSPDAHLPPSQLLG 698
Score = 45.4 bits (106), Expect = 0.001
Identities = 60/226 (26%), Positives = 88/226 (38%), Gaps = 29/226 (12%)
Query: 2938 KEKKFKINIGKPFMINQGGTEGT-----KP-ECTLCGVKYSARLSIRDHIFSKQHISKVR 2991
K KK I+ P G T KP +CT+C V Y+ ++ H+ S H ++ R
Sbjct: 1352 KMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSR 1411
Query: 2992 ET-VGSQLDR-EKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISL 3049
T S+++ E+ P ++ + E+ KK D G S L +S
Sbjct: 1412 GTKTDSKIEGPERSQEEP---KEGETEGEVGTEKKGPDTSGFI---------SGLPFLSP 1459
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPT---SATSSPALSLS 3106
P L P L P LP FP +L L P P L+L
Sbjct: 1460 PPPPLDLHRFPAPLFT----PPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL- 1514
Query: 3107 SAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPN 3152
A P+L P PPPPP PP + L+ ++ E+ E + P+
Sbjct: 1515 -AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPS 1559
Score = 35.8 bits (81), Expect = 0.78
Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 10/65 (15%)
Query: 1954 SPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPP 2013
+PE P P P PPL V++P+ S PP P P P P P
Sbjct: 1227 TPEASPDPLPEPPL----------ASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAP 1276
Query: 2014 PPPSA 2018
PP A
Sbjct: 1277 PPTMA 1281
Score = 35.8 bits (81), Expect = 0.78
Identities = 27/95 (28%), Positives = 31/95 (32%), Gaps = 31/95 (32%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPP------ 2002
P+ TPPPPP PP A + K N +A P +PP P P
Sbjct: 1519 PVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGN------EAGPSSPPDPLPNEAART 1572
Query: 2003 -------------------PPPPPPPPPPPPPPSA 2018
PPPP PPPP A
Sbjct: 1573 AAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEA 1607
Score = 35.4 bits (80), Expect = 1.0
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 10/69 (14%)
Query: 1989 PLQAPPPTPPPPPPPPPPPPPPPPPP-----PPSAPPQVQLPVS-----LDLPLFPSIMM 2038
PL PP P PPPPP P PP P A Q Q P++ D PL +++
Sbjct: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664
Query: 2039 QPVQHPALP 2047
H P
Sbjct: 665 NGFHHVGAP 673
Score = 35.4 bits (80), Expect = 1.0
Identities = 59/266 (22%), Positives = 102/266 (38%), Gaps = 43/266 (16%)
Query: 1759 QATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISE 1818
+AT P +P PPPP +++ + E S C + S A ++E
Sbjct: 2120 EATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPE-----SEACSLSAGDLSDSSASSLAE 2174
Query: 1819 KPEKPKQEFISEGEG----LKEGKDTKKQKSLEPSIPPPRIASGARG------NAAKALL 1868
PE P S G G + +G ++ ++ S+ + + + L
Sbjct: 2175 -PESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLG 2233
Query: 1869 ENFGF-ELVIQ-YNENRQKVQKKGK---------SGEGEN---TDKLECGTCGKLFSNVL 1914
E G + VIQ + +N + +KK K G E + +C C + +
Sbjct: 2234 EEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYV 2293
Query: 1915 ILKSH---QEHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPP-PPPPPPLPPA 1970
+ H ++H+ A L++ R ++ K Y ++P+ PE PP PP P +
Sbjct: 2294 SCRGHLFSRQHL-------AKLKEAVRAQLKSESKCYDLAPA-PEAPPALKAPPATTPAS 2345
Query: 1971 PPQPSSMG-PVKIPNTVSTPLQAPPP 1995
P ++ P P +S P A PP
Sbjct: 2346 MPLGAAPTLPRLAPVLLSGPALAQPP 2371
Score = 35.0 bits (79), Expect = 1.3
Identities = 48/199 (24%), Positives = 71/199 (35%), Gaps = 21/199 (10%)
Query: 3029 LGLTVQQPGMMDSSSLHGISL-PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPG 3087
LG + Q MD + HG+ L P Y GL G P VL G G +L F + P
Sbjct: 244 LGFSKPQ-AFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARPSS 302
Query: 3088 AGMLGFPTSATSSPALSLSSAPTKP----------LLQTPPPPPPPPPPPPSSSLSGQQT 3137
P +S+ + + A T+ +L PP PP+++ T
Sbjct: 303 ----DIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPT 358
Query: 3138 EQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVG--ETHVDP 3195
+ + + P+ + +EE+ P K L VG E DP
Sbjct: 359 QAKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPA---PVGSPEDPSDP 415
Query: 3196 IQLQALQNAIAGDPASFIG 3214
Q L + PA+F G
Sbjct: 416 PQPYRLADDYTPAPAAFQG 434
Score = 34.7 bits (78), Expect = 1.7
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 279 MCFLCKLSFGYIRSFVTHAVHDHRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEP 338
+C LC+L F ++F+ H H + L + + LS A++Q + + LISFLEP
Sbjct: 238 LCLLCRLGFSKPQAFMDH-TQSHGVKLTPAQYQGLSGS--PAVLQEGDEGCKALISFLEP 294
Query: 339 K 339
K
Sbjct: 295 K 295
Score = 34.7 bits (78), Expect = 1.7
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 8/51 (15%)
Query: 1977 MGPVKIPNTVSTPLQAPPPTPPPP------PPPPPPPPPPPPPPPPSAPPQ 2021
+ P++ PN TP +P P P PP P P P PP P PS P+
Sbjct: 1218 LSPLEGPNL--TPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPE 1266
Score = 34.7 bits (78), Expect = 1.7
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 26/79 (32%)
Query: 1925 GQFFPY--------AALEKFARQYREAYDK--------LYPISPSSPET----------P 1958
GQF P+ A F Q + AY + L+P++P P+T
Sbjct: 2477 GQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQ 2536
Query: 1959 PPPPPPPPLPPAPPQPSSM 1977
PPP PP P APP+P +
Sbjct: 2537 PPPQPPEPTATAPPKPPEL 2555
Score = 34.3 bits (77), Expect = 2.3
Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 21/107 (19%)
Query: 3054 PGLPGLPPVLLPGMNGPSSLPGFP------QNSNTLTPPGAGMLGFPTSATSSPALSLSS 3107
PG P V P P+SLP F + P FP P +L+S
Sbjct: 2055 PGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPY-----PTATLAS 2109
Query: 3108 APTKPLLQ-----TPPPPPPP----PPPPPSSSLSGQQTEQQNKESE 3145
P +P L T P P PP PPPPPS ++ + + ESE
Sbjct: 2110 GP-QPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESE 2155
Score = 33.9 bits (76), Expect = 3.0
Identities = 49/250 (19%), Positives = 90/250 (36%), Gaps = 26/250 (10%)
Query: 1173 QCPYCNYNSRDQSRIQMHVL-SQHSVQPVIC------------CPLCQDVLSNKMHLQLH 1219
+C C++ S + ++Q+H + H I C LC +++ + H
Sbjct: 822 RCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQH 881
Query: 1220 LTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKYSGES 1279
L +L + P + L + + TPA V +G + +
Sbjct: 882 LRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAG--NSQP 939
Query: 1280 PMDDKSMAGLEDSKANVEVKNEEQKPTKEPLEVSEWNKNSSKDVKIPDTLQDQLNEQQKR 1339
D G E ++ + +++K K+ EW + S+ + D +
Sbjct: 940 GTIDPEGTGEEPARGCQRLHLKKKKKKKK-----EWGRASAASKGLCD---GGSHPSLTL 991
Query: 1340 QPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHS-QYHAIRAATMCNLCQRSFRTFQALKKH 1398
+PL + VY C +CS +++ H+ HA++ C LCQ AL H
Sbjct: 992 RPLPICSLQVYC--CPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFH 1049
Query: 1399 LEAGHPELSE 1408
L H + E
Sbjct: 1050 LSHLHNVVPE 1059
Score = 33.5 bits (75), Expect = 3.9
Identities = 15/38 (39%), Positives = 17/38 (44%)
Query: 1977 MGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPP 2014
M P + + L PPP PP P PP PP P P
Sbjct: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAP 2558
Score = 32.7 bits (73), Expect = 6.6
Identities = 14/34 (41%), Positives = 16/34 (47%)
Query: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIP 1983
+ P T P P PP PL P PP GP + P
Sbjct: 2115 LPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPP 2148
Score = 32.3 bits (72), Expect = 8.6
Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 23/147 (15%)
Query: 1343 SVSDRHVYKYRCNHCSLAFKTMQKLQIH---------SQYHAIRAAT-----MCNLCQRS 1388
SVS H+ RCN C + +K+Q+H SQ + +R C LC
Sbjct: 815 SVSPLHL---RCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWE 871
Query: 1389 FRTFQALKKHLEA-GHPELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYE 1447
+ A+ +HL H + QL + P E A +++ HG + E
Sbjct: 872 TPSRLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHG-QLRTPAEVV 930
Query: 1448 VDHEGKASPVGSDSSSIPDDMGSEPKR 1474
G + P D P+ G EP R
Sbjct: 931 PAEAGNSQPGTID----PEGTGEEPAR 953
Score = 32.3 bits (72), Expect = 8.6
Identities = 23/75 (30%), Positives = 25/75 (33%), Gaps = 16/75 (21%)
Query: 1959 PPPPPPPPLPPAPPQPSSMGPV----------------KIPNTVSTPLQAPPPTPPPPPP 2002
P PP PPA P G IP T+ L PPP PP
Sbjct: 2483 PLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPP 2542
Query: 2003 PPPPPPPPPPPPPPS 2017
P PP PP P+
Sbjct: 2543 EPTATAPPKPPELPA 2557
>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2790
Score = 500 bits (1287), Expect = e-140
Identities = 301/779 (38%), Positives = 401/779 (51%), Gaps = 98/779 (12%)
Query: 562 ASASKDSATAAHPSEIARGDED----------SSATPHQHGFTPSTPGTP-GPGGDGSPG 610
A S +A A P G E+ SS T + G P+ G+P P P
Sbjct: 444 AKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPY 503
Query: 611 SGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP 670
+ SL HM+++HSRNSCKTLKCPKCNWHYKYQQTL+ HM+EKHPE
Sbjct: 504 RLADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPES 563
Query: 671 GGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNL 730
C YC G HPRLARGESY CGYKP+RC+VCNYSTTTKGNLSIHMQSDKHL N+Q
Sbjct: 564 NSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGF 623
Query: 731 QNGNGEQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEK 790
Q G G Q A P ++ +PK K +W+C+VC YETN++RNLRIHMTSEK
Sbjct: 624 QAGPGGQGSPTEASLPPSA-------GDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEK 676
Query: 791 HMHNMMLLQQNMKQIQHNLHLGLAP----------------AEAELYQYYLAQNIGL--- 831
HM N+++L Q L LGL P + EL+QY+ Q +G
Sbjct: 677 HMQNVLMLHQ-------GLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQT 729
Query: 832 ----TGMKLENPADPQLMINPFQLDPATAAAL---APG-------------LGELS---- 867
G++ + P + QL++N F A A APG LG S
Sbjct: 730 PLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLP 789
Query: 868 ---PYISDPALKLFQCAVCNKFTSDSLEALSVHVSSERSLPEEEWRAVIGDIYQCKLCNY 924
P +LK+F+C VC F++DSLE L H S RSLPE EW+ V GD ++CKLC Y
Sbjct: 790 TSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCY 849
Query: 925 NTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKSNEWRLKCIAIG--------NPVHLKCN 976
TQLKANFQLH KTDKH QKYQL AH++EGG + ++G +P+HL+CN
Sbjct: 850 GTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPA-SLGDGAPYGSVSPLHLRCN 908
Query: 977 ACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQKQEGAVNPESCYYYCAVCDYTTKVKLNL 1036
CD+ +NS +K++LH HE ++YK + E Y+C +C + T +L +
Sbjct: 909 ICDFESNSKEKMQLHARGAAHEENSQIYK------VRLGAELGLYHCLLCAWETPSRLAV 962
Query: 1037 VQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPNELETASLGARTCDDDL 1096
+QH+R+ H+ + R+LQL Q G EE L+ + + +L T + +
Sbjct: 963 LQHLRTPAHRDAQAQRRLQLLQNGPTTEE-GLAALQSILSFSHGQLRTPA------EVVP 1015
Query: 1097 TEQHEEAEGAIKPTAVAEDDEKDTSERDNSEGKNSNKDSVSVAGGTQPLLLAKEEDVATK 1156
E G I P E+ + + K K+ + ++ L T
Sbjct: 1016 AEAGNSQPGTIDPEGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGSHPSLTL 1075
Query: 1157 RSKPTEDNKFCHEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHL 1216
R P C Q Y CPYC++ S + S+++ H LSQH+VQP CPLCQ+ L + L
Sbjct: 1076 RPLP-----ICSLQVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPAL 1130
Query: 1217 QLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKY 1275
HL+HLH+V P+CVEKLL+ V V L+ A + + G G +
Sbjct: 1131 HFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDLIRAVQEGRKRQGYSGRCMCWGQGAF 1189
Score = 270 bits (691), Expect = 1e-71
Identities = 204/641 (31%), Positives = 283/641 (44%), Gaps = 140/641 (21%)
Query: 2854 SETSSIADPSSPNPFGSSNPFKSKSN--DRPGHKRFRTQMSNLQLKVLKACFSDYRTPTM 2911
S SS+A+P SP G+S + D G +R+RTQMS+LQLK++KAC+ YRTPTM
Sbjct: 2251 SSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTM 2310
Query: 2912 QECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGT----KPECTLC 2967
QECE+LG EIGLPKRV+QVWFQNARAKEKK K+ G G +EG + +C C
Sbjct: 2311 QECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ-GTAAGSTGGSSEGLLAAQRTDCPYC 2369
Query: 2968 GVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASD 3027
VKY +S R H+FS+QH++K++E V +QL E K D
Sbjct: 2370 DVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSES---------------------KCYD 2408
Query: 3028 VLGLTVQQPGMMDSSSLHGISLPT-AYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPP 3086
+ P + + S+P A P LP L PVLL G G N+
Sbjct: 2409 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAA 2468
Query: 3087 GAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPP---------PPPPPPSSSLSGQQT 3137
+G+LG TS + + ++ P +PL Q P P P P PP+ L + +
Sbjct: 2469 SSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVS 2528
Query: 3138 EQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQ 3197
++ + + + +K +K L+ T P
Sbjct: 2529 SERKPVAGPTSSSNDALKNLKA--LKTTVP------------------------------ 2556
Query: 3198 LQALQNAIAGDPASFIGGQFLPYFIPGFASYFTPQLPGT-VQGGYFPPVCGMES-LFPYG 3255
+ +GGQFLP+ +P P + G +QG YF + GM+ LFP
Sbjct: 2557 -------------ALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMN 2603
Query: 3256 PTMPQTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQKPVQAKTSKVESDQPQNS 3315
P +PQTL GL P ALLQ Q +P K
Sbjct: 2604 PMIPQTLIGLLPNALLQP-------------------PPQPPEPTATAPPKPPELPAPGE 2644
Query: 3316 NDASETKEDKSTATESTKEEPQLESKSADFSDTYVVPFVKYEFICRKCQMMFTDEDAAVN 3375
+A E E + +T + + V + ++CR+C+M F E A
Sbjct: 2645 GEAGEVDELLTGSTGISTVD------------------VTHRYLCRQCKMAFDGEAPATA 2686
Query: 3376 HQKSFCYFGQPLIDPQETVLRVPVSKYQCLACDVAISGNEALSQHLQSSLHKEK------ 3429
HQ+SFC+FG+ LRVP+ Y CLAC+V +SG EAL+ HL+SS H+ K
Sbjct: 2687 HQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSGREALASHLRSSAHRRKAAPPQG 2746
Query: 3430 -----------TIKQAMRNAKEHVRLLPHSVCSPNPNTTST 3459
A+ AKE R LPH+ +P TTST
Sbjct: 2747 GPPISITNAATAASAAVAFAKEEAR-LPHTDSNPKTTTTST 2786
Score = 228 bits (581), Expect = 8e-59
Identities = 211/738 (28%), Positives = 285/738 (38%), Gaps = 209/738 (28%)
Query: 1955 PETPPPPPP------------PPPLPPAPPQPSSM-------------------GPVKIP 1983
P PPPPP PP LPP P P S+ GP
Sbjct: 1539 PFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL 1598
Query: 1984 NTVSTPLQAPPPTPPPPPPPPP----------PP---------PPPPPPPPPSAPPQVQL 2024
+ L P TPPPPP PP PP P PP P P+ +
Sbjct: 1599 AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAA 1658
Query: 2025 PVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLCQQQLGLDPNFL---RH 2081
L+ F ++ A+PP P +AL C L N L H
Sbjct: 1659 KALLENFGFELVIQYNEGKQAVPPPPTP--PPPEALGGGDKLACGACGKLFSNMLILKTH 1716
Query: 2082 SQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQ 2141
+ R + L Y + +AE K
Sbjct: 1717 EEHVHRRFL----PFEALSRYAAQFRKSYDSLYPPLAEPP----------------KPPD 1756
Query: 2142 RNKDSPYNFSNPPITVLEDIR-----------------IDPQPTSLEHYKSDASFSKRSS 2184
+ DSP PP V E I+ + +S + +R S
Sbjct: 1757 GSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFS 1816
Query: 2185 RTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQA 2244
RT+FT++Q + LQ FF+T+AYPKD E+E+L+++L L +RV+VVWFQNARQKARK N
Sbjct: 1817 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK---NAC 1873
Query: 2245 ETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQT 2304
E T C++C+ F +F+L+ H KK CY D+ + ++E
Sbjct: 1874 EGGSMPTGGGTGGAS--------GCRRCHATFSCVFELVRHLKK-CYDDQTLEEEEE--- 1921
Query: 2305 EDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYP 2364
E E+ + E
Sbjct: 1922 ------------------------------------------------EAERGEEEEEVE 1933
Query: 2365 AEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTP 2424
E+ ++ P G + LP + QA + G+ P TP
Sbjct: 1934 EEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAG------------GKEPEEKATP 1981
Query: 2425 VPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFL 2484
PS + CDQC ++F + +L H+ +HFL + L
Sbjct: 1982 SPSPA------------------HTCDQCAISFSSQDLLTSHRRLHFLPS----LQPSAP 2019
Query: 2485 ERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNN 2544
+ +D+P ++F NPL+ A++S P LKRK +D +
Sbjct: 2020 PQLLDLPLLVFGERNPLV---------------AATSPMPGPP-----LKRKHEDGSLSP 2059
Query: 2545 CSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVV 2604
+ GG + RDKRLRTTI PEQLEILY Y+ DSNPTRKMLD I+ EVGLKKRVV
Sbjct: 2060 TGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVV 2119
Query: 2605 QVWFQNTRARERKGQFRA 2622
QVWFQNTRARERKGQFR+
Sbjct: 2120 QVWFQNTRARERKGQFRS 2137
Score = 186 bits (473), Expect = 3e-46
Identities = 118/308 (38%), Positives = 158/308 (51%), Gaps = 65/308 (21%)
Query: 1426 AESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMGSEPKRTLPFRKGPNFT 1485
A TM++++ G E+ A P +DS + L +RK NF
Sbjct: 1359 APPPTMAEEEEGTTGELR---------SAEPAPADS-----------RHPLTYRKTTNFA 1398
Query: 1486 MEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSP------VPQET 1539
++KFLDP+RPYKCTVCKESFTQKNILLVHYNSVSHLHK+KK + S+P P T
Sbjct: 1399 LDKFLDPARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTT 1458
Query: 1540 NSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS 1599
+ TD KP+KC++C V+Y+QSSTLEIHMRSVLHQT++R K + + +
Sbjct: 1459 TAATD-KPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTD------------SKIEG 1505
Query: 1600 PGQGMLDSMSLAAVNSKDTHLDAKELNKKQTPD---LISAQPAHHPPQSPAQIQMQLQHE 1656
P + + K+ + + +K+ PD IS P PP P +
Sbjct: 1506 PERSQEE--------PKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHR----- 1552
Query: 1657 LQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGTEFSLGPDLGLPGSA- 1715
F P LP FP+ PE+LL+ QQ Q L PFY+ + +GP L L G A
Sbjct: 1553 -------FPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYL--HDLKVGPKLTLAGPAP 1603
Query: 1716 TFGMPGMT 1723
+P T
Sbjct: 1604 VLSLPAAT 1611
Score = 130 bits (328), Expect = 2e-29
Identities = 79/177 (44%), Positives = 100/177 (56%), Gaps = 12/177 (6%)
Query: 1820 PEKPKQEFISEGEGLKEGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQY 1879
P+ PK E ++E E + K+ PS PP + + A AAKALLENFGFELVIQY
Sbjct: 1616 PQPPKAE-LAEREWERPPM-AKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQY 1673
Query: 1880 NENRQKVQKKGKSGEGE---NTDKLECGTCGKLFSNVLILKSHQEHVHGQFFPYAALEKF 1936
NE +Q V E DKL CG CGKLFSN+LILK+H+EHVH +F P+ AL ++
Sbjct: 1674 NEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRY 1733
Query: 1937 ARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAP 1993
A Q+R++YD LYP P PP PP L P P P +P + +AP
Sbjct: 1734 AAQFRKSYDSLYP-----PLAEPPKPPDGSLD--SPVPHLGPPFLVPEPEAGGTRAP 1783
Score = 65.1 bits (157), Expect = 1e-09
Identities = 56/189 (29%), Positives = 82/189 (43%), Gaps = 41/189 (21%)
Query: 2515 PPQASSSHTTAPTTVAASLKR-KLDDKEDNNCSEKE----GGNSG--------EDQHRDK 2561
PP+AS P + A SL L D ++ +E E GG SG D +
Sbjct: 2231 PPKAS------PESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQR 2284
Query: 2562 RLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFR 2621
R RT ++ QL+I+ Y PT + + + E+GL KRV+QVWFQN RA+E+K + +
Sbjct: 2285 RYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ 2344
Query: 2622 AVGP-----------AQSHKRCPFCRALFKAKSALESHIRSR-HWNEGKQA--------- 2660
A CP+C + + H+ SR H + K+A
Sbjct: 2345 GTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSES 2404
Query: 2661 -GYSLPPSP 2668
Y L P+P
Sbjct: 2405 KCYDLAPAP 2413
Score = 60.1 bits (144), Expect = 4e-08
Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 18/203 (8%)
Query: 1957 TPPPPPPPPPLPPAPPQPSSM-------GPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPP 2009
TP P P PPA P+S+ G V P + P P P P P
Sbjct: 2138 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2197
Query: 2010 PPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHP-ALPPQLALQLPQMDALSADLTQLC 2068
PP + P + P+ L P PS P + P A P A L D + + L
Sbjct: 2198 FLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLA 2257
Query: 2069 QQQL----------GLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMA 2118
+ + G +R RT+++ QLKI++A ++ +P+ ++ + +
Sbjct: 2258 EPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLG 2317
Query: 2119 EKSGLSQKVIKHWFRNTLFKERQ 2141
E+ GL ++VI+ WF+N KE++
Sbjct: 2318 EEIGLPKRVIQVWFQNARAKEKK 2340
Score = 57.0 bits (136), Expect = 3e-07
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 5/78 (6%)
Query: 2869 GSSNPFKSKSN-----DRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGL 2923
GS +P S++ + P KR RT + QL++L + PT + + + E+GL
Sbjct: 2055 GSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGL 2114
Query: 2924 PKRVVQVWFQNARAKEKK 2941
KRVVQVWFQN RA+E+K
Sbjct: 2115 KKRVVQVWFQNTRARERK 2132
Score = 53.1 bits (126), Expect = 5e-06
Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 11/135 (8%)
Query: 2855 ETSSIADPSSPNPFGSSNPFKSKSNDR-------PGHKRF-RTQMSNLQLKVLKACFSDY 2906
E P + G P + + + R P +RF RT+ + Q + L++ F
Sbjct: 1776 EAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETS 1835
Query: 2907 RTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGTKPECTL 2966
P E E L + +GL RVV VWFQNAR K +K G M GGT G C
Sbjct: 1836 AYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGS--MPTGGGTGGAS-GCRR 1892
Query: 2967 CGVKYSARLSIRDHI 2981
C +S + H+
Sbjct: 1893 CHATFSCVFELVRHL 1907
Score = 51.2 bits (121), Expect = 2e-05
Identities = 72/309 (23%), Positives = 116/309 (37%), Gaps = 46/309 (14%)
Query: 1875 LVIQYNENRQKVQKKGKSGE-----GENTDKLECGTCGKLFSNVLILKSHQEHVHGQFFP 1929
+V+ + RQK +K G G C C FS V L H + +
Sbjct: 1857 VVVWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTL 1916
Query: 1930 YAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTP 1989
E+ R E + + PP P P P PP + + +T
Sbjct: 1917 EEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPL--PEPPDGEELSQAE-----ATK 1969
Query: 1990 LQAPPPTPPPPPPPPPPPPPPP--------------------PPPPPSAPPQVQLPVSLD 2029
P P P P P PSAPPQ+ LD
Sbjct: 1970 AGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQL-----LD 2024
Query: 2030 LPLFPSIMMQPVQHPALP-PQLALQLPQMD-ALSADLTQLCQQQLGLDPNFLRHSQFKRP 2087
LPL P+ P P L+ D +LS ++ G P + KR
Sbjct: 2025 LPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPP------RDKRL 2078
Query: 2088 RTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQ-RNKDS 2146
RT I +QL+IL ++ +++P+ + + ++E+ GL ++V++ WF+NT +ER+ + + +
Sbjct: 2079 RTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRST 2138
Query: 2147 PYNFSNPPI 2155
P +P +
Sbjct: 2139 PGGVPSPAV 2147
Score = 50.1 bits (118), Expect = 4e-05
Identities = 92/450 (20%), Positives = 146/450 (32%), Gaps = 73/450 (16%)
Query: 2267 YQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTD 2326
++C C V + + L H + ++ + +S+ E + ++ K G+
Sbjct: 1466 FKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEP--KEGETEGEVG 1523
Query: 2327 AAKNAAAPAASSGSGTSTPLIPSPKPE------------PEKTSPKPEYPAEKPKQSD-- 2372
K +SG + P + P P P P P P K
Sbjct: 1524 TEKKGPD---TSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQ 1580
Query: 2373 -------------PSPPSQGTKPALPL-ASTSSDPPQASTAQ--PQPQPQPPKQPQLIGR 2416
P G P L L A+T PPQ A+ + +PP +
Sbjct: 1581 LLLPFYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEA 1640
Query: 2417 PPSASQTPVPSSPLQISMTSLQNSL----------------------PPQLL----QYQC 2450
PS+ P+P+ + + +L + PP+ L + C
Sbjct: 1641 GPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLAC 1700
Query: 2451 DQCTVAFPT---LELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYM-IFDPNNPLMTGQL 2506
C F L+ +EH H FL + ++ + D Y + +P P
Sbjct: 1701 GACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKP--PDGS 1758
Query: 2507 LGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRL-RT 2565
L S + + P A T A + + E GN +R RT
Sbjct: 1759 LDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRT 1818
Query: 2566 TITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERK-----GQF 2620
T Q + L + + P ++ +A +GL RVV VWFQN R + RK G
Sbjct: 1819 KFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSM 1878
Query: 2621 RAVGPAQSHKRCPFCRALFKAKSALESHIR 2650
G C C A F L H++
Sbjct: 1879 PTGGGTGGASGCRRCHATFSCVFELVRHLK 1908
Score = 49.3 bits (116), Expect = 7e-05
Identities = 88/377 (23%), Positives = 141/377 (37%), Gaps = 57/377 (15%)
Query: 2181 KRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSY 2240
+R RT+ + QL++++ ++ P E E L + LP RVI VWFQNAR K
Sbjct: 2283 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAK----- 2337
Query: 2241 ENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQD 2300
E +A+ + + + C C+V + H + Q
Sbjct: 2338 EKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSR---------QH 2388
Query: 2301 ESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPS-PKPEPEKTS- 2358
++ ++++ A + K ++ +A AP A++ + P+ P+ P S
Sbjct: 2389 LAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSG 2448
Query: 2359 ---PKPEYPAEKPKQSDPSPPS----------------QGTKPALPLAS-TSSDPPQAST 2398
+P P S P+ S Q P PL D ST
Sbjct: 2449 PALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTST 2508
Query: 2399 A-QPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQN-----SLPPQLLQYQCDQ 2452
A P P PP +P +G S+ + PV + P S +L+N + P LL Q
Sbjct: 2509 AGTTDPVPGPPTEP--LGDKVSSERKPV-AGPTSSSNDALKNLKALKTTVPALLGGQ--- 2562
Query: 2453 CTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLG---S 2509
+ FP F L + ++ M +F P NP++ L+G +
Sbjct: 2563 -FLPFPLPPAGGTAPPAVF----GPQLQGAYFQQLYGMKKGLF-PMNPMIPQTLIGLLPN 2616
Query: 2510 SLTQMPPQASSSHTTAP 2526
+L Q PPQ TAP
Sbjct: 2617 ALLQPPPQPPEPTATAP 2633
Score = 47.4 bits (111), Expect = 3e-04
Identities = 47/189 (24%), Positives = 71/189 (37%), Gaps = 23/189 (12%)
Query: 697 KPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGNGEQVFGHSAPAPNTSLSGCGTP 756
+P++C VC S T K L +H S HL+ ++ G + P T T
Sbjct: 1407 RPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTT------TA 1460
Query: 757 SPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLAPA 816
+ KP ++C VC N + L IHM S H + + K I+ P
Sbjct: 1461 ATDKP-----FKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSK-IEGPERSQEEPK 1514
Query: 817 EAELYQYYLAQNIG------LTGMKLENPADPQLMINPFQLDPATAAALAPGLGELSPYI 870
E E + G ++G+ +P P L ++ F T L P P +
Sbjct: 1515 EGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPP-----FPLV 1569
Query: 871 SDPALKLFQ 879
+ LKL Q
Sbjct: 1570 PESLLKLQQ 1578
Score = 47.0 bits (110), Expect = 3e-04
Identities = 75/325 (23%), Positives = 111/325 (34%), Gaps = 45/325 (13%)
Query: 1433 QDDHGLEQEMEREYEVDHEGKA--SPVGS--DSSSIP------DDMGSEPKRTLPFRKGP 1482
++D GL + + EG +PVGS D S P DD P
Sbjct: 464 EEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYRLADDYTPAPAAFQGLSLSS 523
Query: 1483 NFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSV---SHLHKLKKVLQEASSPVPQET 1539
+ ++ + + KC C + + L VH S+ H A + +
Sbjct: 524 HMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGE 583
Query: 1540 NSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS 1599
+ N KPY+C +CN + + L IHM+S H + + P G G + A+ S
Sbjct: 584 SYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQ--GSPTEASLPPS 641
Query: 1600 PG--QGMLDSMSLAAVNSKDTHLDAKELNKKQT--------------------PDLISAQ 1637
G + S V S +T++ ++ L T P L+
Sbjct: 642 AGDKEPKTKSSWQCKVCSYETNI-SRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPG 700
Query: 1638 PAHHPPQSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALL----QFQQPQFL 1693
P P +P Q+ Q Q P P P+ + LL P
Sbjct: 701 PPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARK 760
Query: 1694 FPFYIPGTEFSLGPDLGLPGSATFG 1718
FP PG SL PD LP S G
Sbjct: 761 FPTSAPG---SLSPDAHLPPSQLLG 782
Score = 45.4 bits (106), Expect = 0.001
Identities = 60/226 (26%), Positives = 88/226 (38%), Gaps = 29/226 (12%)
Query: 2938 KEKKFKINIGKPFMINQGGTEGT-----KP-ECTLCGVKYSARLSIRDHIFSKQHISKVR 2991
K KK I+ P G T KP +CT+C V Y+ ++ H+ S H ++ R
Sbjct: 1436 KMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSR 1495
Query: 2992 ET-VGSQLDR-EKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISL 3049
T S+++ E+ P ++ + E+ KK D G S L +S
Sbjct: 1496 GTKTDSKIEGPERSQEEP---KEGETEGEVGTEKKGPDTSGFI---------SGLPFLSP 1543
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPT---SATSSPALSLS 3106
P L P L P LP FP +L L P P L+L
Sbjct: 1544 PPPPLDLHRFPAPLFT----PPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL- 1598
Query: 3107 SAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPN 3152
A P+L P PPPPP PP + L+ ++ E+ E + P+
Sbjct: 1599 -AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPS 1643
Score = 35.8 bits (81), Expect = 0.78
Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 10/65 (15%)
Query: 1954 SPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPP 2013
+PE P P P PPL V++P+ S PP P P P P P
Sbjct: 1311 TPEASPDPLPEPPL----------ASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAP 1360
Query: 2014 PPPSA 2018
PP A
Sbjct: 1361 PPTMA 1365
Score = 35.4 bits (80), Expect = 1.0
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 10/69 (14%)
Query: 1989 PLQAPPPTPPPPPPPPPPPPPPPPPP-----PPSAPPQVQLPVS-----LDLPLFPSIMM 2038
PL PP P PPPPP P PP P A Q Q P++ D PL +++
Sbjct: 689 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 748
Query: 2039 QPVQHPALP 2047
H P
Sbjct: 749 NGFHHVGAP 757
Score = 35.4 bits (80), Expect = 1.0
Identities = 59/266 (22%), Positives = 102/266 (38%), Gaps = 43/266 (16%)
Query: 1759 QATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISE 1818
+AT P +P PPPP +++ + E S C + S A ++E
Sbjct: 2204 EATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPE-----SEACSLSAGDLSDSSASSLAE 2258
Query: 1819 KPEKPKQEFISEGEG----LKEGKDTKKQKSLEPSIPPPRIASGARG------NAAKALL 1868
PE P S G G + +G ++ ++ S+ + + + L
Sbjct: 2259 -PESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLG 2317
Query: 1869 ENFGF-ELVIQ-YNENRQKVQKKGK---------SGEGEN---TDKLECGTCGKLFSNVL 1914
E G + VIQ + +N + +KK K G E + +C C + +
Sbjct: 2318 EEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYV 2377
Query: 1915 ILKSH---QEHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPP-PPPPPPLPPA 1970
+ H ++H+ A L++ R ++ K Y ++P+ PE PP PP P +
Sbjct: 2378 SCRGHLFSRQHL-------AKLKEAVRAQLKSESKCYDLAPA-PEAPPALKAPPATTPAS 2429
Query: 1971 PPQPSSMG-PVKIPNTVSTPLQAPPP 1995
P ++ P P +S P A PP
Sbjct: 2430 MPLGAAPTLPRLAPVLLSGPALAQPP 2455
Score = 35.0 bits (79), Expect = 1.3
Identities = 48/199 (24%), Positives = 71/199 (35%), Gaps = 21/199 (10%)
Query: 3029 LGLTVQQPGMMDSSSLHGISL-PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPG 3087
LG + Q MD + HG+ L P Y GL G P VL G G +L F + P
Sbjct: 328 LGFSKPQ-AFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARPSS 386
Query: 3088 AGMLGFPTSATSSPALSLSSAPTKP----------LLQTPPPPPPPPPPPPSSSLSGQQT 3137
P +S+ + + A T+ +L PP PP+++ T
Sbjct: 387 ----DIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPT 442
Query: 3138 EQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVG--ETHVDP 3195
+ + + P+ + +EE+ P K L VG E DP
Sbjct: 443 QAKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPA---PVGSPEDPSDP 499
Query: 3196 IQLQALQNAIAGDPASFIG 3214
Q L + PA+F G
Sbjct: 500 PQPYRLADDYTPAPAAFQG 518
Score = 35.0 bits (79), Expect = 1.3
Identities = 23/87 (26%), Positives = 29/87 (33%), Gaps = 27/87 (31%)
Query: 1949 PISPSSPETPPPPPPPPPL---------PPAPPQPSSMGPVKIPNTVSTP---------- 1989
P+ TPPPPP PP PP + + GP P+ +
Sbjct: 1603 PVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALL 1662
Query: 1990 --------LQAPPPTPPPPPPPPPPPP 2008
+Q PPPP PPPP
Sbjct: 1663 ENFGFELVIQYNEGKQAVPPPPTPPPP 1689
Score = 34.7 bits (78), Expect = 1.7
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 279 MCFLCKLSFGYIRSFVTHAVHDHRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEP 338
+C LC+L F ++F+ H H + L + + LS A++Q + + LISFLEP
Sbjct: 322 LCLLCRLGFSKPQAFMDH-TQSHGVKLTPAQYQGLSGS--PAVLQEGDEGCKALISFLEP 378
Query: 339 K 339
K
Sbjct: 379 K 379
Score = 34.7 bits (78), Expect = 1.7
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 8/51 (15%)
Query: 1977 MGPVKIPNTVSTPLQAPPPTPPPP------PPPPPPPPPPPPPPPPSAPPQ 2021
+ P++ PN TP +P P P PP P P P PP P PS P+
Sbjct: 1302 LSPLEGPNL--TPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPE 1350
Score = 34.7 bits (78), Expect = 1.7
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 26/79 (32%)
Query: 1925 GQFFPY--------AALEKFARQYREAYDK--------LYPISPSSPET----------P 1958
GQF P+ A F Q + AY + L+P++P P+T
Sbjct: 2561 GQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQ 2620
Query: 1959 PPPPPPPPLPPAPPQPSSM 1977
PPP PP P APP+P +
Sbjct: 2621 PPPQPPEPTATAPPKPPEL 2639
Score = 34.3 bits (77), Expect = 2.3
Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 21/107 (19%)
Query: 3054 PGLPGLPPVLLPGMNGPSSLPGFP------QNSNTLTPPGAGMLGFPTSATSSPALSLSS 3107
PG P V P P+SLP F + P FP P +L+S
Sbjct: 2139 PGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPY-----PTATLAS 2193
Query: 3108 APTKPLLQ-----TPPPPPPP----PPPPPSSSLSGQQTEQQNKESE 3145
P +P L T P P PP PPPPPS ++ + + ESE
Sbjct: 2194 GP-QPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESE 2239
Score = 33.9 bits (76), Expect = 3.0
Identities = 49/250 (19%), Positives = 90/250 (36%), Gaps = 26/250 (10%)
Query: 1173 QCPYCNYNSRDQSRIQMHVL-SQHSVQPVIC------------CPLCQDVLSNKMHLQLH 1219
+C C++ S + ++Q+H + H I C LC +++ + H
Sbjct: 906 RCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQH 965
Query: 1220 LTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKYSGES 1279
L +L + P + L + + TPA V +G + +
Sbjct: 966 LRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAG--NSQP 1023
Query: 1280 PMDDKSMAGLEDSKANVEVKNEEQKPTKEPLEVSEWNKNSSKDVKIPDTLQDQLNEQQKR 1339
D G E ++ + +++K K+ EW + S+ + D +
Sbjct: 1024 GTIDPEGTGEEPARGCQRLHLKKKKKKKK-----EWGRASAASKGLCD---GGSHPSLTL 1075
Query: 1340 QPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHS-QYHAIRAATMCNLCQRSFRTFQALKKH 1398
+PL + VY C +CS +++ H+ HA++ C LCQ AL H
Sbjct: 1076 RPLPICSLQVYC--CPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFH 1133
Query: 1399 LEAGHPELSE 1408
L H + E
Sbjct: 1134 LSHLHNVVPE 1143
Score = 33.5 bits (75), Expect = 3.9
Identities = 15/38 (39%), Positives = 17/38 (44%)
Query: 1977 MGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPP 2014
M P + + L PPP PP P PP PP P P
Sbjct: 2605 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAP 2642
Score = 32.7 bits (73), Expect = 6.6
Identities = 14/34 (41%), Positives = 16/34 (47%)
Query: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIP 1983
+ P T P P PP PL P PP GP + P
Sbjct: 2199 LPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPP 2232
Score = 32.3 bits (72), Expect = 8.6
Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 23/147 (15%)
Query: 1343 SVSDRHVYKYRCNHCSLAFKTMQKLQIH---------SQYHAIRAAT-----MCNLCQRS 1388
SVS H+ RCN C + +K+Q+H SQ + +R C LC
Sbjct: 899 SVSPLHL---RCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWE 955
Query: 1389 FRTFQALKKHLEA-GHPELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYE 1447
+ A+ +HL H + QL + P E A +++ HG + E
Sbjct: 956 TPSRLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHG-QLRTPAEVV 1014
Query: 1448 VDHEGKASPVGSDSSSIPDDMGSEPKR 1474
G + P D P+ G EP R
Sbjct: 1015 PAEAGNSQPGTID----PEGTGEEPAR 1037
Score = 32.3 bits (72), Expect = 8.6
Identities = 23/75 (30%), Positives = 25/75 (33%), Gaps = 16/75 (21%)
Query: 1959 PPPPPPPPLPPAPPQPSSMGPV----------------KIPNTVSTPLQAPPPTPPPPPP 2002
P PP PPA P G IP T+ L PPP PP
Sbjct: 2567 PLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPP 2626
Query: 2003 PPPPPPPPPPPPPPS 2017
P PP PP P+
Sbjct: 2627 EPTATAPPKPPELPA 2641
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 89.7 bits (221), Expect = 5e-17
Identities = 42/80 (52%), Positives = 49/80 (61%), Gaps = 9/80 (11%)
Query: 1959 PPPPPPPPLPPAPPQPSSM--GPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPP 2016
P PPPPPPLPP+ P ++ GPV TP PPP PPPPPPPPPPPPPPPP P P
Sbjct: 525 PLPPPPPPLPPSSDTPETVQNGPV-------TPPMPPPPPPPPPPPPPPPPPPPPPLPGP 577
Query: 2017 SAPPQVQLPVSLDLPLFPSI 2036
+A P++ LP P +
Sbjct: 578 AAETVPAPPLAPPLPSAPPL 597
Score = 67.8 bits (164), Expect = 2e-10
Identities = 38/85 (44%), Positives = 39/85 (45%), Gaps = 33/85 (38%)
Query: 1949 PISPSS---------PETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPP 1999
P+ PSS P TPP PPPPPP PP PP PPP PPP
Sbjct: 532 PLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPP--------------------PPPPPPP 571
Query: 2000 PPPPPPP----PPPPPPPPPPSAPP 2020
PP P P P PP PP PSAPP
Sbjct: 572 PPLPGPAAETVPAPPLAPPLPSAPP 596
Score = 62.4 bits (150), Expect = 8e-09
Identities = 35/89 (39%), Positives = 43/89 (48%), Gaps = 28/89 (31%)
Query: 1975 SSMGPVKIPNTVSTPLQAPPPTPP---------------PPPPPPPPPPPPPPPPPPSAP 2019
+S GP+ P PPP PP P PPPPPPPPPPPPPPPP P
Sbjct: 521 ASSGPLPPP---------PPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPP 571
Query: 2020 PQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048
P + P + +P P + P+ P+ PP
Sbjct: 572 PPLPGPAAETVPAPP--LAPPL--PSAPP 596
Score = 44.3 bits (103), Expect = 0.002
Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
Query: 3079 NSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPP 3128
+S L PP P +S ++ + P P + PPPPPPPPPPPP
Sbjct: 522 SSGPLPPPPP-----PLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPP 566
Score = 42.4 bits (98), Expect = 0.008
Identities = 24/69 (34%), Positives = 28/69 (40%), Gaps = 15/69 (21%)
Query: 3070 PSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPS 3129
P P P +S+T P + + P P P PPPPPPPPPPPP
Sbjct: 527 PPPPPPLPPSSDT-----------PETVQNGPVTPPMPPPPPP----PPPPPPPPPPPPP 571
Query: 3130 SSLSGQQTE 3138
L G E
Sbjct: 572 PPLPGPAAE 580
Score = 42.0 bits (97), Expect = 0.011
Identities = 36/115 (31%), Positives = 45/115 (39%), Gaps = 8/115 (6%)
Query: 2323 GQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKP 2382
G A N+ P + G+ +S PL P P P P +S PE P + P PP P
Sbjct: 505 GSEVVAGNSVGP--TMGAASSGPLPPPPPPLPP-SSDTPETVQNGPV-TPPMPPPPPPPP 560
Query: 2383 ALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSL 2437
P PP + P PP P L PSA P SSP + + L
Sbjct: 561 PPPPPPPPPPPPPLPGPAAETVPAPPLAPPL----PSAPPLPGTSSPTVVFNSGL 611
Score = 37.0 bits (84), Expect = 0.35
Identities = 49/247 (19%), Positives = 85/247 (34%), Gaps = 13/247 (5%)
Query: 2196 LQDFFDTNAYPKDDEIE-----QLSTVLNLPTRVIVVWFQNARQKARKSYENQAETKDNE 2250
L ++ D + + D+++ L V ++ + +NA + + E +
Sbjct: 349 LDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEK 408
Query: 2251 KRELTNERYIRTSNMQYQC----KKCNVVFPRIFDLIT--HQKKQCYKDEDDDAQDESQT 2304
++ NE + ++ Q K+ +VV D T H ++ K++++ Q +S
Sbjct: 409 LQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTL 468
Query: 2305 EDSMDATDQVVYKHCTVSGQTDAA--KNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPE 2362
E + ++ G D A A+ S GS P + P P
Sbjct: 469 EKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPP 528
Query: 2363 YPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQ 2422
P P SD Q P+ PP P P P P P P
Sbjct: 529 PPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLA 588
Query: 2423 TPVPSSP 2429
P+PS+P
Sbjct: 589 PPLPSAP 595
Score = 35.8 bits (81), Expect = 0.78
Identities = 24/68 (35%), Positives = 25/68 (36%), Gaps = 21/68 (30%)
Query: 2003 PPPPPPPP--------------------PPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQ 2042
P PPPPPP PPPPPP PP P PL P + V
Sbjct: 525 PLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPL-PGPAAETVP 583
Query: 2043 HPALPPQL 2050
P L P L
Sbjct: 584 APPLAPPL 591
Score = 35.8 bits (81), Expect = 0.78
Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
Query: 2005 PPPPPPPPPPPPSAPPQV--QLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSA 2062
P PPPPPP PP S P+ PV+ +P P P P PP L P + + A
Sbjct: 525 PLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPA 584
Score = 32.7 bits (73), Expect = 6.6
Identities = 14/25 (56%), Positives = 15/25 (60%)
Query: 3106 SSAPTKPLLQTPPPPPPPPPPPPSS 3130
S PT + P PPPPPP PPSS
Sbjct: 513 SVGPTMGAASSGPLPPPPPPLPPSS 537
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 86.7 bits (213), Expect = 4e-16
Identities = 53/126 (42%), Positives = 61/126 (48%), Gaps = 20/126 (15%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIP--------NTVSTPLQAPP-PTPPP 1999
P P+ P PPP PPPPP P PP PSS P+K P + P+ APP P PP
Sbjct: 166 PPRPNVPAPPPPTPPPPPPPLPPPLPSS-SPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP 224
Query: 2000 PPPPPPPPPPPPPPP---------PPSAPPQVQLPVSLDLPLFPSIMMQPVQ-HPALPPQ 2049
PPPPPPPP PPP PP P P P+ LPL P ++ PA P Q
Sbjct: 225 PPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQ 284
Query: 2050 LALQLP 2055
A + P
Sbjct: 285 DAQEPP 290
Score = 85.1 bits (209), Expect = 1e-15
Identities = 48/113 (42%), Positives = 56/113 (49%), Gaps = 16/113 (14%)
Query: 1951 SPSSPETPPPPPP--PPPLPPAPPQPSSMGPVKIPNTVSTPLQAPP------PTPPPPPP 2002
+P P P PPPP PPP PP PP S P+K TPL +PP P PP
Sbjct: 165 APPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIK------TPLVSPPGPLTKGNLPVVAPP 218
Query: 2003 PPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLP 2055
P PPPPPPPPPP+ PP V D + P + P+ P +PP L L P
Sbjct: 219 VPCAPPPPPPPPPPTPPPLPPASVLSDKAVKP--QLAPLHLPPIPPPLPLLPP 269
Score = 62.8 bits (151), Expect = 6e-09
Identities = 41/116 (35%), Positives = 48/116 (41%), Gaps = 11/116 (9%)
Query: 1954 SPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPP 2013
SP P P +PPA P+ +G + + P P PPPP PPPPPPP PP
Sbjct: 132 SPRLPNKTISGPLIPPASPR---LGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPP 188
Query: 2014 PPPSAPPQVQLPVSLDLPL--------FPSIMMQPVQHPALPPQLALQLPQMDALS 2061
P PS+ P VS PL P + P P PP LP LS
Sbjct: 189 PLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLS 244
Score = 61.2 bits (147), Expect = 2e-08
Identities = 40/125 (32%), Positives = 47/125 (37%), Gaps = 35/125 (28%)
Query: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPP----------- 1998
++P P PPPPPPPPP P P P+S+ K PL PP PP
Sbjct: 215 VAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPG 274
Query: 1999 --------------PPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHP 2044
PP PP PP PP S P+ LP P P + P
Sbjct: 275 LKAEPASPAQDAQEPPAPP------PPLPPYASCSPRASLPA----PPLPGVNSSSETPP 324
Query: 2045 ALPPQ 2049
LPP+
Sbjct: 325 PLPPK 329
Score = 59.7 bits (143), Expect = 5e-08
Identities = 48/135 (35%), Positives = 53/135 (39%), Gaps = 49/135 (36%)
Query: 1949 PISPSSPETPPPPPPP--PPLPPAP--------PQ--PSSMGPVKIPNTVSTPLQAP--- 1993
P P +P PPPPPPP PPLPPA PQ P + P+ P + P P
Sbjct: 217 PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLK 276
Query: 1994 ------------PPTPPPPPPP----------PPPP----------PPPPPPPPPS--AP 2019
PP PPPP PP P PP PPP PP PS AP
Sbjct: 277 AEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336
Query: 2020 PQVQLPVSLDLPLFP 2034
PQ +L P P
Sbjct: 337 PQKAGAQALPAPPAP 351
Score = 57.8 bits (138), Expect = 2e-07
Identities = 22/27 (81%), Positives = 22/27 (81%)
Query: 1994 PPTPPPPPPPPPPPPPPPPPPPPSAPP 2020
PP PPPP PPPPPP PPPPPPSAPP
Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPP 30
Score = 53.9 bits (128), Expect = 3e-06
Identities = 30/84 (35%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 1946 KLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP 2005
K P SP+ PP PPPP P A P + P V++ + PPP PP P
Sbjct: 276 KAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQA 335
Query: 2006 PPPP------PPPPPPPSAPPQVQ 2023
PP P PP PP + P +Q
Sbjct: 336 PPQKAGAQALPAPPAPPGSQPFLQ 359
Score = 48.5 bits (114), Expect = 1e-04
Identities = 19/29 (65%), Positives = 19/29 (65%)
Query: 1989 PLQAPPPTPPPPPPPPPPPPPPPPPPPPS 2017
P PPP PPPPPP PPPPPP PP S
Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVS 32
Score = 48.5 bits (114), Expect = 1e-04
Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 3065 PGMNGPSSLPGFPQN--SNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPP 3122
PG PS P P S L PP + LG TS + +AP +P + PPPP P
Sbjct: 126 PGSRAPS--PRLPNKTISGPLIPPASPRLG----NTSEAHGAARTAPPRPNVPAPPPPTP 179
Query: 3123 PPPPPP 3128
PPPPPP
Sbjct: 180 PPPPPP 185
Score = 46.2 bits (108), Expect = 6e-04
Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 22/94 (23%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAP 3109
PT P P LPP L PSS P + ++PPG P + + P + AP
Sbjct: 177 PTPPPPPPPLPPPL------PSSSP---IKTPLVSPPG------PLTKGNLPVV----AP 217
Query: 3110 TKPLLQTPPPPPPPPPP---PPSSSLSGQQTEQQ 3140
P PPPPPPPP P PP+S LS + + Q
Sbjct: 218 PVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQ 251
Score = 45.8 bits (107), Expect = 8e-04
Identities = 24/52 (46%), Positives = 24/52 (46%), Gaps = 23/52 (44%)
Query: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPP 2009
P PPPPPPPLPP PP PL APPP PPP PP
Sbjct: 2 PVPPPPPPPLPPPPP----------------PLGAPPP-------PPPSAPP 30
Score = 43.9 bits (102), Expect = 0.003
Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 5/94 (5%)
Query: 3047 ISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLS 3106
+ LP P LP LPP PG+ + P PP P A+ SP SL
Sbjct: 255 LHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPP-----PLPPYASCSPRASLP 309
Query: 3107 SAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQ 3140
+ P + + PPP PP PS Q+ Q
Sbjct: 310 APPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343
Score = 42.0 bits (97), Expect = 0.011
Identities = 40/122 (32%), Positives = 50/122 (40%), Gaps = 23/122 (18%)
Query: 2333 APAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQG------TKPALPL 2386
A AS P P+P P P P Y + P+ S P+PP G T P LP
Sbjct: 277 AEPASPAQDAQEP--PAPPP------PLPPYASCSPRASLPAPPLPGVNSSSETPPPLPP 328
Query: 2387 ASTSSD-PPQASTAQPQPQP------QPPKQPQLIGRPPS--ASQTPVPSSPLQISMTSL 2437
S S PPQ + AQ P P QP Q + GRP + P P+ P + T L
Sbjct: 329 KSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTEL 388
Query: 2438 QN 2439
+
Sbjct: 389 SS 390
Score = 41.2 bits (95), Expect = 0.019
Identities = 36/102 (35%), Positives = 40/102 (39%), Gaps = 9/102 (8%)
Query: 2334 PAASSGSGTSTPLIPSPKPEPEKTSP--KPEYPAEKPKQSDPSPPSQGTKPALPLASTSS 2391
P S S TPL+ P P + P P P P P PP T P LP AS S
Sbjct: 188 PPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPP---TPPPLPPASVLS 244
Query: 2392 DPPQASTAQPQPQPQPPKQPQLIGRPPSA--SQTPVPSSPLQ 2431
D +A Q P PP P L PP P+SP Q
Sbjct: 245 D--KAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQ 284
Score = 40.8 bits (94), Expect = 0.024
Identities = 39/129 (30%), Positives = 49/129 (37%), Gaps = 12/129 (9%)
Query: 2323 GQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKP-KQSDPSPPSQGTK 2381
G T A AA A + P P P P P P P+ P K SPP TK
Sbjct: 153 GNTSEAHGAARTAPPR---PNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTK 209
Query: 2382 PALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSL 2441
LP+ + P A P P P PP P + PP++ + P Q++ L
Sbjct: 210 GNLPVVA-----PPVPCAPPPPPPPPPPTPPPL--PPASVLSDKAVKP-QLAPLHLPPIP 261
Query: 2442 PPQLLQYQC 2450
PP L C
Sbjct: 262 PPLPLLPPC 270
Score = 40.0 bits (92), Expect = 0.041
Identities = 18/32 (56%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPV 1980
P+ P P PP PPPPPPL PP P S PV
Sbjct: 2 PVPPPPP--PPLPPPPPPLGAPPPPPPSAPPV 31
Score = 39.3 bits (90), Expect = 0.071
Identities = 35/122 (28%), Positives = 49/122 (40%), Gaps = 15/122 (12%)
Query: 2322 SGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTK 2381
+GQ D A +G G + PSP+ P KT P P P+ + S +
Sbjct: 112 AGQRDVA------GGKTGQGPGSRA-PSPRL-PNKTISGPLIPPASPRLGNTSEAHGAAR 163
Query: 2382 PALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSL 2441
A P + + PP T P P P PP P S +TP+ S P ++ +L
Sbjct: 164 TAPPRPNVPAPPP--PTPPPPPPPLPPPLPS-----SSPIKTPLVSPPGPLTKGNLPVVA 216
Query: 2442 PP 2443
PP
Sbjct: 217 PP 218
Score = 38.5 bits (88), Expect = 0.12
Identities = 41/156 (26%), Positives = 56/156 (35%), Gaps = 32/156 (20%)
Query: 3109 PTKPLLQTPPPPPP---PPPPPPSSSLSGQQTEQQNKESEK----------KQTKPNKVK 3155
P P PPPPPP PPPPPPS+ T + K + T+ KV
Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVT 63
Query: 3156 KIKEEELEATKPEKHPKKE------EKISSALSVLGKVVGETHVDPIQLQALQNAIAGDP 3209
+I + + K KE + +S LG + P+ A Q +AG
Sbjct: 64 QINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGF--PVLRPAGQRDVAGGK 121
Query: 3210 ASFIGGQFLPYFIPGFASYFTPQLPG-TVQGGYFPP 3244
G P +P+LP T+ G PP
Sbjct: 122 TGQGPGSRAP----------SPRLPNKTISGPLIPP 147
Score = 38.5 bits (88), Expect = 0.12
Identities = 41/143 (28%), Positives = 55/143 (38%), Gaps = 30/143 (20%)
Query: 2323 GQTDAAKNAAAPAASSGSGT-STPLIPSPKPEPEKTS----------PKPEYPAEKPKQS 2371
G+T + AP+ + T S PLIP P TS P+P PA P
Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
Query: 2372 DPSPPSQGTKPALPLASTSS----DPPQAST-------AQPQPQPQPPKQPQLIGRPPSA 2420
P PP P LP +S PP T A P P PP P PP
Sbjct: 180 PPPPPP--LPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP-----PPPP 232
Query: 2421 SQTPVPSSPLQISMTSLQNSLPP 2443
+ P+P + + +S +++ L P
Sbjct: 233 TPPPLPPASV-LSDKAVKPQLAP 254
Score = 38.5 bits (88), Expect = 0.12
Identities = 29/93 (31%), Positives = 34/93 (36%), Gaps = 7/93 (7%)
Query: 3048 SLPTAYPGLP-GLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPAL--- 3103
+LP P +P PP P P LP S+ P L P P L
Sbjct: 211 NLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPC 270
Query: 3104 ---SLSSAPTKPLLQTPPPPPPPPPPPPSSSLS 3133
L + P P PP PPPP PP +S S
Sbjct: 271 GYPGLKAEPASPAQDAQEPPAPPPPLPPYASCS 303
Score = 38.5 bits (88), Expect = 0.12
Identities = 30/116 (25%), Positives = 38/116 (32%), Gaps = 12/116 (10%)
Query: 2345 PLIPSPKPEPEKTSPKPEYPAE-----------KPKQSDPSPPSQGTKPALPLASTSSDP 2393
P P P P P +P P PA P P PP P ++P
Sbjct: 220 PCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP 279
Query: 2394 PQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQ 2449
+ +P PP P P AS P P P S + LPP+ +Q
Sbjct: 280 ASPAQDAQEPPAPPPPLPPYASCSPRAS-LPAPPLPGVNSSSETPPPLPPKSPSFQ 334
Score = 35.0 bits (79), Expect = 1.3
Identities = 15/28 (53%), Positives = 17/28 (60%), Gaps = 3/28 (10%)
Query: 1952 PSSPETPPPPPP---PPPLPPAPPQPSS 1976
P P PPPPPP PPP PP+ P S+
Sbjct: 6 PPPPPLPPPPPPLGAPPPPPPSAPPVST 33
Score = 33.9 bits (76), Expect = 3.0
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSM 1977
P+ P P PPPPPP PP SS+
Sbjct: 10 PLPPPPPPLGAPPPPPPSAPPVSTDTSSL 38
Score = 33.1 bits (74), Expect = 5.1
Identities = 12/20 (60%), Positives = 13/20 (65%)
Query: 2006 PPPPPPPPPPPSAPPQVQLP 2025
P PPPPPPP P PP + P
Sbjct: 2 PVPPPPPPPLPPPPPPLGAP 21
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 85.1 bits (209), Expect = 1e-15
Identities = 43/87 (49%), Positives = 46/87 (52%), Gaps = 13/87 (14%)
Query: 1947 LYPISPSSPETPPPPPPPPP--------LPPAPPQ-PSSMGPVKIPNTVSTPLQAPPPTP 1997
L P + +P PPPPPP P P APPQ P G + P P PPP P
Sbjct: 530 LAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPP 589
Query: 1998 PPPPPP----PPPPPPPPPPPPPSAPP 2020
PPPPPP P PPPPPPPPPPP PP
Sbjct: 590 PPPPPPGTDGPVPPPPPPPPPPPGGPP 616
Score = 76.6 bits (187), Expect = 4e-13
Identities = 41/84 (48%), Positives = 43/84 (51%), Gaps = 18/84 (21%)
Query: 1952 PSSPETPPPPPP----------PPPLPP-APPQPSSMGPVKIPNTVSTPLQAPPPTPPPP 2000
P+ PPPPPP PP PP APP P S P P + L PPP PPPP
Sbjct: 536 PAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAP-PLPGDLPPPPPPPPPP 594
Query: 2001 P------PPPPPPPPPPPPPPPSA 2018
P PPPPPPPPPPP PP A
Sbjct: 595 PGTDGPVPPPPPPPPPPPGGPPDA 618
Score = 68.9 bits (167), Expect = 8e-11
Identities = 35/79 (44%), Positives = 40/79 (50%), Gaps = 9/79 (11%)
Query: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPP--PTPPPPPPPPPPP 2007
++P++ P PPPPP P P P P S P QAPP +P PPP PP P
Sbjct: 530 LAPAAEPAPGAAPPPPPPLPGLPSPQEAPP-------SAPPQAPPLPGSPEPPPAPPLPG 582
Query: 2008 PPPPPPPPPSAPPQVQLPV 2026
PPPPPPP PP PV
Sbjct: 583 DLPPPPPPPPPPPGTDGPV 601
Score = 52.0 bits (123), Expect = 1e-05
Identities = 32/84 (38%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1968 PPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQV-QLPV 2026
P P+ P P+ P P P PPPPPP P P P PPSAPPQ LP
Sbjct: 511 PSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPG 570
Query: 2027 SLDLPLFPSIM--MQPVQHPALPP 2048
S + P P + + P P PP
Sbjct: 571 SPEPPPAPPLPGDLPPPPPPPPPP 594
Score = 51.2 bits (121), Expect = 2e-05
Identities = 34/100 (34%), Positives = 37/100 (37%), Gaps = 13/100 (13%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008
P SP+ P P P P PP P +P S P PP PP PP
Sbjct: 522 PTGSPSPDLAPAAEPAPGAAPPPPPP-------LPGLPS------PQEAPPSAPPQAPPL 568
Query: 2009 PPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048
P P PPP+ P LP P P PV P PP
Sbjct: 569 PGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPP 608
Score = 47.8 bits (112), Expect = 2e-04
Identities = 36/110 (32%), Positives = 44/110 (40%), Gaps = 14/110 (12%)
Query: 1946 KLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPP-- 2003
++ P++ ++P P P +P P P + P P P APPP PP P P
Sbjct: 502 EILPVAVATPSGGDAPTPG--VPTGSPSPD-LAPAAEP----APGAAPPPPPPLPGLPSP 554
Query: 2004 ---PPPPPPPPPPPP--PSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048
PP PP PP P P PP LP L P P P PP
Sbjct: 555 QEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPP 604
Score = 47.4 bits (111), Expect = 3e-04
Identities = 35/108 (32%), Positives = 43/108 (39%), Gaps = 16/108 (14%)
Query: 3027 DVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLPPVLLPGMNG----PSSLPGFPQNSNT 3082
++L + V P D+ + +PT P P L P P P LPG P
Sbjct: 502 EILPVAVATPSGGDAPTP---GVPTGSPS-PDLAPAAEPAPGAAPPPPPPLPGLPSPQEA 557
Query: 3083 LTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSS 3130
PP A P + P P PL PPPPPPPPPPP +
Sbjct: 558 --PPSAPPQAPPLPGSPEPP------PAPPLPGDLPPPPPPPPPPPGT 597
Score = 46.6 bits (109), Expect = 4e-04
Identities = 39/124 (31%), Positives = 47/124 (37%), Gaps = 17/124 (13%)
Query: 2312 DQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKP---------- 2361
D V + V+ T + +A P +GS S L P+ +P P P P
Sbjct: 497 DAVSIEILPVAVATPSGGDAPTPGVPTGS-PSPDLAPAAEPAPGAAPPPPPPLPGLPSPQ 555
Query: 2362 EYPAEKPKQSDPSPPSQGTKPALPLAST-----SSDPPQASTAQPQPQPQPPKQPQLIGR 2416
E P P Q+ P P S PA PL PP T P P P PP P G
Sbjct: 556 EAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPP-PGG 614
Query: 2417 PPSA 2420
PP A
Sbjct: 615 PPDA 618
Score = 44.3 bits (103), Expect = 0.002
Identities = 30/101 (29%), Positives = 36/101 (35%), Gaps = 6/101 (5%)
Query: 2333 APAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSP----PSQGTKPALPLAS 2388
A A SG TP +P+ P P+ P P P P P + A P A
Sbjct: 507 AVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAP 566
Query: 2389 TSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSP 2429
P+ A P P PP P PP + PVP P
Sbjct: 567 PLPGSPEPPPAPPLPGDLPPPPPP--PPPPPGTDGPVPPPP 605
Score = 44.3 bits (103), Expect = 0.002
Identities = 38/107 (35%), Positives = 44/107 (41%), Gaps = 15/107 (14%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGML--GFPTSATSSPALSLSS 3107
P P LPGLP P PS+ P P + PP A L P P +
Sbjct: 542 PPPPPPLPGLPS---PQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTD 598
Query: 3108 APTKPLLQTPPPPPPPPPPP--PSSSLSGQQTEQQNKESEKK--QTK 3150
P PPPPPPPPPPP P +L + +E KK QTK
Sbjct: 599 GPV------PPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTK 639
Score = 43.9 bits (102), Expect = 0.003
Identities = 43/145 (29%), Positives = 55/145 (37%), Gaps = 33/145 (22%)
Query: 1931 AALEKFARQYREAYDKL---YPISPSSPETPPPPPPPPPLPPAPPQPSSM---------- 1977
A LEK Q R+ + L + S + + PP P P AP +PS++
Sbjct: 427 AELEKQLSQARKELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEK 486
Query: 1978 GPVKI-------------PNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQL 2024
G ++I P V+TP PTP P P P P P P A P
Sbjct: 487 GLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPP 546
Query: 2025 PVSLDLPLFPSIMMQPVQHPALPPQ 2049
P LP PS P P+ PPQ
Sbjct: 547 P----LPGLPSPQEAP---PSAPPQ 564
Score = 42.7 bits (99), Expect = 0.006
Identities = 32/107 (29%), Positives = 40/107 (37%), Gaps = 10/107 (9%)
Query: 3037 GMMDSSSLHGISLPTAYPGLPGLPPVLLP-GMNGPSSLPGFPQNSNTLTPPGAGMLGFPT 3095
G D+ S+ + + A P P +P G P P PP + G P
Sbjct: 494 GPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLP- 552
Query: 3096 SATSSPALSLSSAPTKPLLQTPPP--------PPPPPPPPPSSSLSG 3134
S +P + AP P PPP PPPPPPPPP G
Sbjct: 553 SPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDG 599
Score = 38.9 bits (89), Expect = 0.092
Identities = 27/76 (35%), Positives = 31/76 (40%), Gaps = 8/76 (10%)
Query: 2376 PSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIG------RPPSA--SQTPVPS 2427
PS G P + + S P A A+P P PP P L G PPSA P+P
Sbjct: 511 PSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPG 570
Query: 2428 SPLQISMTSLQNSLPP 2443
SP L LPP
Sbjct: 571 SPEPPPAPPLPGDLPP 586
Score = 37.4 bits (85), Expect = 0.27
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 8/53 (15%)
Query: 1949 PISPSSPETPPPPPPPPPLPP--APP-----QPSSMGP-VKIPNTVSTPLQAP 1993
P P + P PPPPPPP PP PP + S +GP VK + T + P
Sbjct: 591 PPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMP 643
Score = 33.9 bits (76), Expect = 3.0
Identities = 39/178 (21%), Positives = 64/178 (35%), Gaps = 20/178 (11%)
Query: 2985 QHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSL 3044
+H+ +++E V +R +D + + +++L + +K + L + M +S
Sbjct: 399 EHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARKELETLRERFSESTAMGASRR 458
Query: 3045 --HGISLPTAYPGLPGLPPV---------LLPGMNGPSSLPGFPQNSNTLTPPGAGMLGF 3093
P A P P + L+ + GP + P G
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPT 518
Query: 3094 PTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKP 3151
P T SP+ L+ A P P PPPPPP L G + Q+ S Q P
Sbjct: 519 PGVPTGSPSPDLAPAAE------PAPGAAPPPPPP---LPGLPSPQEAPPSAPPQAPP 567
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 85.1 bits (209), Expect = 1e-15
Identities = 50/121 (41%), Positives = 58/121 (47%), Gaps = 19/121 (15%)
Query: 1949 PISPSSPETPPPPPPP-------PPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPP 2001
P P E PPP PPP PP PP PPQP+ P P V+ +PPP P PPP
Sbjct: 1448 PEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP---PPLVAPTPSSPPPPPLPPP 1504
Query: 2002 PPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALS 2061
PPP P PPPPPPP +AP L + P PS + P LP L L + +
Sbjct: 1505 PPPAMPSPPPPPPPAAAP----LAAPPEEPAAPS-----PEDPELPDTRPLHLAKKQETA 1555
Query: 2062 A 2062
A
Sbjct: 1556 A 1556
Score = 72.8 bits (177), Expect = 6e-12
Identities = 48/119 (40%), Positives = 53/119 (44%), Gaps = 21/119 (17%)
Query: 1949 PISPSSPETPPPPP----PPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP 2004
P S+P+ PP P P PP P P +S G + P P PPP P P P PP
Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP 1472
Query: 2005 PPPPPP------PPP---PPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQL 2054
PPPPPP PPP P PS+PP LP P P M P P PP A L
Sbjct: 1473 PPPPPPQPALPSPPPLVAPTPSSPPPPPLP-----PPPPPAMPSP---PPPPPPAAAPL 1523
Score = 54.3 bits (129), Expect = 2e-06
Identities = 43/127 (33%), Positives = 53/127 (41%), Gaps = 36/127 (28%)
Query: 1956 ETPPPPPP---------------------PPPLPPAPPQ--PS--SMGPVKIPNTVSTPL 1990
++PPPPPP P LPP PPQ PS S P P+ +
Sbjct: 762 KSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGV 821
Query: 1991 QAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDL----PLFPSIMMQPVQHPAL 2046
P P PPPPPPPPPPP P +QL L P PS ++P + +L
Sbjct: 822 HLLEPATRDGAPQPPPPPPPPPPPMP-----LQLEAHLRSHGLEPAAPSPRLRPEE--SL 874
Query: 2047 PPQLALQ 2053
P A+Q
Sbjct: 875 DPPGAMQ 881
Score = 54.3 bits (129), Expect = 2e-06
Identities = 40/132 (30%), Positives = 46/132 (34%), Gaps = 5/132 (3%)
Query: 1938 RQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTP 1997
R +E+ P P P PP P + GP +P S P P
Sbjct: 1392 RDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPP 1451
Query: 1998 PPPPPPPPPPP----PPPPPPPPSAPPQVQLPVSLDLPL-FPSIMMQPVQHPALPPQLAL 2052
PPP PP P P PPPP PPQ LP L PS P P PP +
Sbjct: 1452 LLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPS 1511
Query: 2053 QLPQMDALSADL 2064
P +A L
Sbjct: 1512 PPPPPPPAAAPL 1523
Score = 53.9 bits (128), Expect = 3e-06
Identities = 55/202 (27%), Positives = 74/202 (36%), Gaps = 25/202 (12%)
Query: 1842 KQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKV---QKKGKSGEGENT 1898
+ LEP+ P PR+ + A+ E G + V +GK G
Sbjct: 855 RSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYR 914
Query: 1899 DKLECGTCGKLF---SNVLILKSHQEHVHGQFFPYAALEKFARQYREAYDKLYPIS---- 1951
GT F +++ S + FFP E F + Y K P
Sbjct: 915 SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTME-EMFGGGAADDYGKAGPPEDEGD 973
Query: 1952 PSSPETPPPPPPP--PPLPPAPPQPSSMGPV------------KIPNTVSTPLQAPPPTP 1997
P + PPP PP P P P + S GP ++P+TV+ +
Sbjct: 974 PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSG 1033
Query: 1998 PPPPPPPPPPPPPPPPPPPSAP 2019
P PPPPPPPPPPP P S P
Sbjct: 1034 PHQAAPPPPPPPPPPPAPASEP 1055
Score = 52.8 bits (125), Expect = 6e-06
Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 16/118 (13%)
Query: 3015 AQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLPPVLLPGMNGPSSLP 3074
+ E D + K D+ +D L G + G P P +PG P LP
Sbjct: 1381 SSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG---PPPLP 1437
Query: 3075 GFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSL 3132
G P ++ TP P L PT P TP P PPPPPPPP +L
Sbjct: 1438 GLPSANSNGTP-------------EPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPAL 1482
Score = 52.0 bits (123), Expect = 1e-05
Identities = 32/95 (33%), Positives = 40/95 (42%), Gaps = 13/95 (13%)
Query: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPP 2009
+ P+ P PPPPP + P + V L P P PPPPPPPP
Sbjct: 783 LEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPP 842
Query: 2010 PPPPP------------PPSAP-PQVQLPVSLDLP 2031
PPP P P+AP P+++ SLD P
Sbjct: 843 PPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPP 877
Score = 52.0 bits (123), Expect = 1e-05
Identities = 39/157 (24%), Positives = 57/157 (36%), Gaps = 21/157 (13%)
Query: 2293 DEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIP---- 2348
DE+D ++S+ + + ++G D + P A + + P +P
Sbjct: 1383 DEEDSVAKNRDLQESISSAISAL-DDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPS 1441
Query: 2349 -----SPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALP-----LASTSSD------ 2392
+P+P + P P P Q P PP +PALP +A T S
Sbjct: 1442 ANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPL 1501
Query: 2393 PPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSP 2429
PP A P P P PP + PP P P P
Sbjct: 1502 PPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDP 1538
Score = 46.6 bits (109), Expect = 4e-04
Identities = 33/114 (28%), Positives = 41/114 (35%), Gaps = 20/114 (17%)
Query: 1962 PPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPP---------PPPPP--------- 2003
PPPPP QP+ G + PL PPP P P P P
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
Query: 2004 --PPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLP 2055
P P PPPP PP +P+ L+ L + P L P+ +L P
Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPP 877
Score = 46.6 bits (109), Expect = 4e-04
Identities = 56/211 (26%), Positives = 75/211 (35%), Gaps = 27/211 (12%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAP 3109
PTA P P LL GP P L P P+ + S + L
Sbjct: 769 PTAQSTQP-TPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPA 827
Query: 3110 TKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEELEATKPEK 3169
T+ PPPPPPPPPPP L + + S + + EE L+
Sbjct: 828 TRDGAPQPPPPPPPPPPPMPLQL------EAHLRSHGLEPAAPSPRLRPEESLDP----- 876
Query: 3170 HPKKEEKISSALSVLGKVVGETHVDPIQLQALQNAIAGDPASFI-----GGQFLPYFIPG 3224
P +++ AL L G+T V P N+ DPA G P F+P
Sbjct: 877 -PGAMQELLGALEPLPPAPGDTGVGP------PNSEGKDPAGAYRSPSPQGTKAPRFVPL 929
Query: 3225 FASYFTPQLPGTVQGGYFPPVCGMESLFPYG 3255
+ F L + +FP ME +F G
Sbjct: 930 TSICFPDSLLQDEERSFFPT---MEEMFGGG 957
Score = 44.7 bits (104), Expect = 0.002
Identities = 51/171 (29%), Positives = 68/171 (39%), Gaps = 21/171 (12%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGM-----LGFPTSATSSPALS 3104
P A G P PP P GP PG + TP G G+ P++ + P
Sbjct: 974 PKAGAGPPPGPPAYDP--YGPYC-PGRASGAGPETP-GLGLDPNKPPELPSTVNAEPLGL 1029
Query: 3105 LSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEEL-- 3162
+ S P + PPPPPPPPPP P+S G T TKP K+ K L
Sbjct: 1030 IQSGPHQAA--PPPPPPPPPPPAPASEPKGGLT-----SPIFCSTKPKKLLKTSSFHLLR 1082
Query: 3163 EATKPEKHPKK---EEKISSALSVLGKVVGETHVDPIQLQALQNAIAGDPA 3210
P + PKK +E A V + ++P +L L ++ PA
Sbjct: 1083 RRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPA 1133
Score = 43.9 bits (102), Expect = 0.003
Identities = 37/120 (30%), Positives = 46/120 (38%), Gaps = 12/120 (10%)
Query: 2336 ASSGSGTSTPLIPSPK----PEPEKTSPKPEYPAEKPKQSDPSPPSQGT-KPALPLASTS 2390
+S+ S P + PK P+ +P P P PS S GT +P L
Sbjct: 1399 SSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPP 1458
Query: 2391 SDPPQASTAQPQP-------QPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
PP A T QPQP QP P P L+ PS+ P P +M S PP
Sbjct: 1459 PTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP 1518
Score = 42.7 bits (99), Expect = 0.006
Identities = 36/120 (30%), Positives = 44/120 (36%), Gaps = 29/120 (24%)
Query: 1954 SPETPPPPPPPPP--------------LPPAPPQP-----SSMGPVKIPNTVSTPLQAPP 1994
+P+ PPPPPPPPP L PA P P S+ P P + L A
Sbjct: 832 APQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP---PGAMQELLGALE 888
Query: 1995 PTPPPPPPPPPPPPPPPPPPPPSA-----PPQVQLP--VSLDLPLFPSIMMQPVQHPALP 2047
P PP P PP P A P + P V L FP ++Q + P
Sbjct: 889 PLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFP 948
Score = 41.2 bits (95), Expect = 0.019
Identities = 32/93 (34%), Positives = 38/93 (40%), Gaps = 17/93 (18%)
Query: 1948 YPISPSSPETPPPPPPPPP-----------LPP--APPQPSSMGPVKIPNTVSTPLQAPP 1994
+P+ PSS PP PP L P AP PSS+G ++ + P
Sbjct: 162 FPV-PSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERL---AGGGVLGPA 217
Query: 1995 PTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVS 2027
P PP P PP PPPPP P Q L S
Sbjct: 218 GLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLAS 250
Score = 40.0 bits (92), Expect = 0.041
Identities = 28/84 (33%), Positives = 28/84 (33%), Gaps = 20/84 (23%)
Query: 1955 PETPPPPPPPPPLPPAPPQ----PSSMGPVKIPNTVSTPLQAPPPTPPPPPPP------- 2003
P P PP PPPP P Q SS S L P PPPP
Sbjct: 226 PYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQ 285
Query: 2004 ---------PPPPPPPPPPPPPSA 2018
P PPPPPPP A
Sbjct: 286 DTVIKHYQRPASAQPPPPPPPAHA 309
Score = 39.3 bits (90), Expect = 0.071
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 1968 PPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVS 2027
PP P + S G K P + APPP P PPP P P PP P+ +P
Sbjct: 1670 PPVPVRRS--GQAKNPVSAGGS-SAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMP-E 1725
Query: 2028 LDLPLFPSIMMQPVQ 2042
P PS +++PV+
Sbjct: 1726 PPAPEKPS-LLRPVE 1739
Score = 39.3 bits (90), Expect = 0.071
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 2352 PEPEKTSPKPEYPAEKPKQSDPSP--PSQGTKPALPLASTSSDPPQASTAQPQPQPQPPK 2409
P P + S + + P S P P P+ KP P +TS PP+ + P+P P+
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPE 1730
Query: 2410 QPQLI 2414
+P L+
Sbjct: 1731 KPSLL 1735
Score = 38.9 bits (89), Expect = 0.092
Identities = 26/83 (31%), Positives = 28/83 (33%), Gaps = 32/83 (38%)
Query: 1952 PSSPETPPPPPPPPPLP------------------------------PAPPQPSSMGPVK 1981
P P P PPPPP LP P PP P P +
Sbjct: 226 PYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQ 285
Query: 1982 IPNTVSTPLQAPPPTPPPPPPPP 2004
+TV Q P PPPPPPP
Sbjct: 286 --DTVIKHYQRPASAQPPPPPPP 306
Score = 38.5 bits (88), Expect = 0.12
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 2345 PLIPSPKP--EPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQ 2402
P +PSP P P +SP P P + PSPP A PLA+ +P S P+
Sbjct: 1480 PALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPE 1539
Query: 2403 -PQPQP 2407
P +P
Sbjct: 1540 LPDTRP 1545
Score = 38.5 bits (88), Expect = 0.12
Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 10/59 (16%)
Query: 1949 PISPSSPETPPPPPP-PPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
P+S PPP P PPP P P + +S P P Q P P PP P P
Sbjct: 1683 PVSAGGSSAPPPKAPAPPPKPETPEKTTSEKP---------PEQTPETAMPEPPAPEKP 1732
Score = 37.4 bits (85), Expect = 0.27
Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 10/80 (12%)
Query: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP---- 2005
+ P++ + P PPPPPP PP PP P + + + +P P PP
Sbjct: 824 LEPATRDGAPQPPPPPP-PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQE 882
Query: 2006 -----PPPPPPPPPPPSAPP 2020
P PP P PP
Sbjct: 883 LLGALEPLPPAPGDTGVGPP 902
Score = 36.2 bits (82), Expect = 0.60
Identities = 21/66 (31%), Positives = 24/66 (36%), Gaps = 21/66 (31%)
Query: 1947 LYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
L P P + +PPPPPPP + PL APP P P P P
Sbjct: 1501 LPPPPPPAMPSPPPPPPP---------------------AAAPLAAPPEEPAAPSPEDPE 1539
Query: 2007 PPPPPP 2012
P P
Sbjct: 1540 LPDTRP 1545
Score = 35.8 bits (81), Expect = 0.78
Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 2345 PLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQ 2404
P PSP+ PE++ P E +P PP+ G P S DP + A P
Sbjct: 861 PAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDP---AGAYRSPS 917
Query: 2405 PQPPKQPQLI 2414
PQ K P+ +
Sbjct: 918 PQGTKAPRFV 927
Score = 35.8 bits (81), Expect = 0.78
Identities = 16/36 (44%), Positives = 17/36 (47%)
Query: 1953 SSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVST 1988
S P PPPPPPP PP P G + P ST
Sbjct: 1032 SGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCST 1067
Score = 35.8 bits (81), Expect = 0.78
Identities = 40/124 (32%), Positives = 53/124 (42%), Gaps = 23/124 (18%)
Query: 2322 SGQTDAAKNAAAPAASSGSGTSTPLIPSPKPE-PEK-TSPKPEYPAEKPKQSDPSPPSQG 2379
SGQ AKN + SS P P PKPE PEK TS KP P + P+ + P PP+
Sbjct: 1677 SGQ---AKNPVSAGGSSAPPPKAPA-PPPKPETPEKTTSEKP--PEQTPETAMPEPPAP- 1729
Query: 2380 TKPAL--PLAS-------TSSDPPQASTAQPQPQPQPPKQPQLIGRP-----PSASQTPV 2425
KP+L P+ T + P + P++ G+P P A T V
Sbjct: 1730 EKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKV 1789
Query: 2426 PSSP 2429
+ P
Sbjct: 1790 KAEP 1793
Score = 33.9 bits (76), Expect = 3.0
Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 16/81 (19%)
Query: 3070 PSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPP- 3128
PS P P + G G+LG PA L A T P PP PPPPP P
Sbjct: 193 PSQAPTVPSSLGFERLAGGGVLG--------PA-GLGPAQTPPYRPGPPDPPPPPRHLPT 243
Query: 3129 ------SSSLSGQQTEQQNKE 3143
SSS + EQ + +
Sbjct: 244 QFNLLASSSAAAAAAEQSSPQ 264
Score = 33.9 bits (76), Expect = 3.0
Identities = 27/100 (27%), Positives = 35/100 (35%), Gaps = 16/100 (16%)
Query: 2350 PKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKP-----------ALPLASTSSDPPQAST 2398
P P P P Y + + P P G P A PL S P QA+
Sbjct: 980 PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAA- 1038
Query: 2399 AQPQPQPQPPKQPQLIGRPPSASQTPV--PSSPLQISMTS 2436
P P P PP P P +P+ + P ++ TS
Sbjct: 1039 --PPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTS 1076
Score = 33.1 bits (74), Expect = 5.1
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 5/35 (14%)
Query: 1988 TPLQAPPPTPPPPPP-----PPPPPPPPPPPPPPS 2017
TP +PP + PP P P PP P P PPPS
Sbjct: 1304 TPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPS 1338
Score = 33.1 bits (74), Expect = 5.1
Identities = 16/65 (24%), Positives = 27/65 (41%)
Query: 2365 AEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTP 2424
A KP P P + + P+++ S P P P+P+ P++ P +T
Sbjct: 1663 ARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETA 1722
Query: 2425 VPSSP 2429
+P P
Sbjct: 1723 MPEPP 1727
Score = 33.1 bits (74), Expect = 5.1
Identities = 17/48 (35%), Positives = 18/48 (37%), Gaps = 7/48 (14%)
Query: 1960 PPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPP 2007
PPP P PP P P T P + P T P PP P P
Sbjct: 1692 PPPKAPAPPPKPETPEK-------TTSEKPPEQTPETAMPEPPAPEKP 1732
Score = 32.7 bits (73), Expect = 6.6
Identities = 41/147 (27%), Positives = 55/147 (37%), Gaps = 38/147 (25%)
Query: 2348 PSPKPE-----------------PEKTSPKPEYPAEKPKQSDPSPPSQGTKPALP----L 2386
PSP P P+ P P P P Q + S G +PA P
Sbjct: 810 PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLR 869
Query: 2387 ASTSSDPP---QASTAQPQPQPQPPKQ-----PQLIGRPPS-ASQTPVP---SSPLQISM 2434
S DPP Q +P P P P G+ P+ A ++P P +P + +
Sbjct: 870 PEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPL 929
Query: 2435 TSLQNSLPPQLLQYQCDQCTVAFPTLE 2461
TS+ P LLQ D+ FPT+E
Sbjct: 930 TSI--CFPDSLLQ---DEERSFFPTME 951
Score = 32.3 bits (72), Expect = 8.6
Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 7/70 (10%)
Query: 3117 PPPPPPPPPPPP------SSSLSGQQTEQQNKESEKKQTKPNKVKKI-KEEELEATKPEK 3169
PPP P PPP P +S +QT + KP+ ++ + KE+E E +
Sbjct: 1692 PPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGE 1751
Query: 3170 HPKKEEKISS 3179
P + E+ +S
Sbjct: 1752 RPLRGERATS 1761
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 82.4 bits (202), Expect = 7e-15
Identities = 93/347 (26%), Positives = 130/347 (37%), Gaps = 54/347 (15%)
Query: 1729 LLEDLKQQIQTQHHVGQTQL-----QILQQ--------QAQQYQATQPQLQPQKQQQQPP 1775
+LED+ QI + G+ Q+ LQQ Q Q Q +QP + Q Q
Sbjct: 246 VLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQK 305
Query: 1776 PPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISEKPEKPKQEFISEGEGLK 1835
PQQ QQQ ++ S S+ Q+ + V + E+ + +P PK
Sbjct: 306 DPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPK----------- 354
Query: 1836 EGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKSGEG 1895
K ++ P +PP + A AL E V + + ++
Sbjct: 355 ----IPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPV 410
Query: 1896 ENTDKLECGTCGKLFSNVLI-LKSHQEHVHGQFFPYAALEKFARQYREAYDKLYPISPSS 1954
L S+ + + + ++ G+ Y +L+ + +Y L P
Sbjct: 411 HQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGE--GYQSLQSMMKTEGPSYGALPPAYGPP 468
Query: 1955 PETPPPP---PPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP-----P 2006
P P PP PP PP PP P+S P IP PPTP PPPPP P
Sbjct: 469 AHLPYHPHVYPPNPPPPPVPPPPASFPPPAIP----------PPTPGYPPPPPTYNPNFP 518
Query: 2007 PPPPPPPP----PPSAPPQVQL-PVSLDLPLFPSIMMQPVQHPALPP 2048
PPPP PP PP PP + L P S P P PV P PP
Sbjct: 519 PPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPP 565
Score = 67.8 bits (164), Expect = 2e-10
Identities = 39/93 (41%), Positives = 46/93 (49%), Gaps = 19/93 (20%)
Query: 1947 LYPISPSSPETPPPP----PP--PPPLPPAPPQPSSMGP------VKIPNTVSTP----- 1989
+YP +P P PPPP PP PPP P PP P + P ++P T + P
Sbjct: 477 VYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPP 536
Query: 1990 -LQAPPPTPPPPPPPPPPPPPPPPP-PPPSAPP 2020
L PP + PPP PP PP PPP PPP PP
Sbjct: 537 GLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPP 569
Score = 61.2 bits (147), Expect = 2e-08
Identities = 48/159 (30%), Positives = 56/159 (35%), Gaps = 57/159 (35%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSM----------------------GPV--KIPN 1984
P P+ PPP P PP PP + M GP +P
Sbjct: 404 PAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP 463
Query: 1985 TVSTPLQAP------PPTPPPPPPPPPP---------------PPPPP------PPPPPS 2017
P P PP PPPPP PPPP PPPPP PPPPP
Sbjct: 464 AYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPR 523
Query: 2018 APPQVQL----PVSLDLP--LFPSIMMQPVQHPALPPQL 2050
PP + P L LP +P + P P +PP +
Sbjct: 524 LPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPI 562
Score = 53.5 bits (127), Expect = 4e-06
Identities = 41/123 (33%), Positives = 50/123 (40%), Gaps = 19/123 (15%)
Query: 1952 PSSPETPPPPPPPPPLPPAP------PQPSSMGPVKIPNTVSTPLQAPPPTPPPPP---- 2001
PS P+ P P PA PQPSS VK VS + PPPP
Sbjct: 299 PSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKI 358
Query: 2002 ----PPPPPPPPPPPPPPP--SAPPQVQLPVSLDLPLFPSIMMQPVQHPA---LPPQLAL 2052
PP PP PPP PP +A + + P +D P + + P HPA PP L
Sbjct: 359 ETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPH 418
Query: 2053 QLP 2055
+ P
Sbjct: 419 RPP 421
Score = 48.9 bits (115), Expect = 9e-05
Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 7/107 (6%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSS-A 3108
P P + P L P P P PPG P AT P + + A
Sbjct: 352 PPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPG------PVDATDLPKVQIPPPA 405
Query: 3109 PTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVK 3155
P+ Q PP P PPPPPPSS ++G T E Q+ + +K
Sbjct: 406 HPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMK 452
Score = 42.7 bits (99), Expect = 0.006
Identities = 43/175 (24%), Positives = 64/175 (36%), Gaps = 22/175 (12%)
Query: 2333 APAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQ---GTKPALPLAST 2389
+P SS ++ SPK E + P P + P PP+ KP L A
Sbjct: 324 SPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALG 383
Query: 2390 SSDPPQA--STAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQ 2447
++PP +T P+ Q PP P + +PP P P P MT +
Sbjct: 384 EAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSY-MTGMST-------- 434
Query: 2448 YQCDQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDMPY--MIFDPNNP 2500
T ++ + E +Q Q M + P P +PY ++ PN P
Sbjct: 435 ------TSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP 483
Score = 41.2 bits (95), Expect = 0.019
Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 12/122 (9%)
Query: 3020 DRIKKASDVLGLTVQQPGMMDSSSLHGISLPT-AYPGLPGLPPVL--LPGMNGPSS-LPG 3075
DR + LG + PG +D++ L + +P A+P PP L P PSS + G
Sbjct: 373 DRKPPLAAALG-EAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTG 431
Query: 3076 FPQNSNTLTPPGAGMLGF------PTSATSSPALSLSS-APTKPLLQTPPPPPPPPPPPP 3128
S+ ++ G L P+ PA + P P + P PPPPP PPPP
Sbjct: 432 MSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPP 491
Query: 3129 SS 3130
+S
Sbjct: 492 AS 493
Score = 39.3 bits (90), Expect = 0.071
Identities = 27/85 (31%), Positives = 35/85 (41%), Gaps = 21/85 (24%)
Query: 2348 PSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQP 2407
P +P P P+ P Q S PSQ ++P S P Q QP Q QP
Sbjct: 270 PHQLQQPPSLQPTPQVP-----QVQQSQPSQSSEP--------SQPQQKDPQQPAQQQQP 316
Query: 2408 PKQPQLIGRPPSASQTPVPSSPLQI 2432
+QP+ +P PSSP Q+
Sbjct: 317 AQQPK--------KPSPQPSSPRQV 333
Score = 38.9 bits (89), Expect = 0.092
Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 15/101 (14%)
Query: 2346 LIPSPK-PEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQ 2404
L P+P+ P+ +++ P +P+Q DP P+Q +PA +P PQ
Sbjct: 279 LQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPA------------QQPKKPSPQ 326
Query: 2405 PQPPKQPQ--LIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
P P+Q + ++ P ++ P P + + LPP
Sbjct: 327 PSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPP 367
Score = 38.5 bits (88), Expect = 0.12
Identities = 28/85 (32%), Positives = 33/85 (38%), Gaps = 9/85 (10%)
Query: 3048 SLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSS 3107
++P PG P PP P N P P P P G LG P ++ PA+
Sbjct: 498 AIPPPTPGYPPPPPTYNP--NFPPPPPRLPPTHAVPPHPPPG-LGLPPASYPPPAVPPGG 554
Query: 3108 APTKPLLQTPPPPPPPPPPPPSSSL 3132
P P PP PPP PP L
Sbjct: 555 QPPVP------PPIPPPGMPPVGGL 573
Score = 37.4 bits (85), Expect = 0.27
Identities = 20/56 (35%), Positives = 23/56 (41%), Gaps = 1/56 (1%)
Query: 2363 YPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPP 2418
YP P P PP+ PA+P T PP T P P PP+ P PP
Sbjct: 478 YPPNPPPPPVPPPPASFPPPAIP-PPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPP 532
Score = 37.0 bits (84), Expect = 0.35
Identities = 45/183 (24%), Positives = 66/183 (36%), Gaps = 23/183 (12%)
Query: 3096 SATSSPALSLSSAPTKPLLQTPPPPPPPPP-PPPSSSLSGQQTEQQNKESEKKQTKPNKV 3154
S +S P+ P +P Q P P P P PSS ++ + + E K +P
Sbjct: 294 SQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPP 353
Query: 3155 KKIKEEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQLQALQNAIAGDPASFIG 3214
K K E P HP + K A + LG+ VD L +Q PA
Sbjct: 354 KIPKIETTHPPLPPAHPPPDRKPPLA-AALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQ 412
Query: 3215 GQFLPY---------FIPGF---ASYFTPQLPGTVQG---------GYFPPVCGMESLFP 3253
LP+ ++ G +SY + + ++Q G PP G + P
Sbjct: 413 PPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLP 472
Query: 3254 YGP 3256
Y P
Sbjct: 473 YHP 475
Score = 37.0 bits (84), Expect = 0.35
Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 4/101 (3%)
Query: 2324 QTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPA 2383
+T+ A P A G P P P P P PA P + P PP+ G P
Sbjct: 452 KTEGPSYGALPPAY-GPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIP-PPTPGYPPP 509
Query: 2384 LPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTP 2424
P + + PP P PP P +G PP++ P
Sbjct: 510 PPTYNPNFPPPPPRL--PPTHAVPPHPPPGLGLPPASYPPP 548
Score = 36.6 bits (83), Expect = 0.46
Identities = 25/85 (29%), Positives = 29/85 (34%), Gaps = 4/85 (4%)
Query: 2345 PLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQ 2404
P P+ P P P P YP P + PP P P + PP P
Sbjct: 488 PPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLP--PTHAVPPHPPPGLGLPPASY 545
Query: 2405 PQPPKQPQLIGRPPSASQTPVPSSP 2429
P P P G+PP P P P
Sbjct: 546 PPPAVPPG--GQPPVPPPIPPPGMP 568
Score = 32.3 bits (72), Expect = 8.6
Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 8/86 (9%)
Query: 3049 LPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNT--LTPPGAGMLGFPTSATSSPALSLS 3106
+ T P LPP P + P +P N + PP A FP A P
Sbjct: 451 MKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPAS---FPPPAIPPPT---P 504
Query: 3107 SAPTKPLLQTPPPPPPPPPPPPSSSL 3132
P P P PPPPP PP+ ++
Sbjct: 505 GYPPPPPTYNPNFPPPPPRLPPTHAV 530
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 81.6 bits (200), Expect = 1e-14
Identities = 45/116 (38%), Positives = 54/116 (46%), Gaps = 24/116 (20%)
Query: 1961 PPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP---------PPPPPP 2011
PPPP +PP PP PS +G + P P+ A PP PPPPPPPPP PPPPPP
Sbjct: 646 PPPPASIPPPPPLPSGLGSLS-PAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPP 704
Query: 2012 P-------PPPPSAPPQVQLPVSLDLPLFPSIMM-------QPVQHPALPPQLALQ 2053
P PP P PP P L P P + Q + PA+ P ++
Sbjct: 705 PPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMK 760
Score = 80.5 bits (197), Expect = 3e-14
Identities = 46/116 (39%), Positives = 56/116 (48%), Gaps = 8/116 (6%)
Query: 1940 YREAYDKLYPISPSSPETPPPPPPPPPL-PPAPPQPSSMGPVKIPNTVSTPLQAPPPTPP 1998
+++ + L P+ + PPPP PP PP PS +G + P P+ A PP PP
Sbjct: 624 HKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLS-PAPPMPPVSAGPPLPP 682
Query: 1999 PPPPPPPPPPP----PPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQL 2050
PPPPPPP PPP PPPPPPP P P + P P P P PP L
Sbjct: 683 PPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGP--PPAPPPPGLAPPPPPGL 736
Score = 49.3 bits (116), Expect = 7e-05
Identities = 39/134 (29%), Positives = 59/134 (44%), Gaps = 12/134 (8%)
Query: 3003 DYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQ----PGMMDSSSLHGISLPTAYPGL-P 3057
D P T R + Q + + K + T + P ++ SSL +S P + +
Sbjct: 570 DDCPPKTFRNVCVQTDRETFLKPCESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHA 629
Query: 3058 GLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTP 3117
L P+ N +LP P + + PP G + + + P +S+ P P P
Sbjct: 630 ALQPMEGMASNQQKALPPPPAS---IPPPPPLPSGLGSLSPAPPMPPVSAGPPLP----P 682
Query: 3118 PPPPPPPPPPPSSS 3131
PPPPPPP PPPSS+
Sbjct: 683 PPPPPPPLPPPSSA 696
Score = 44.7 bits (104), Expect = 0.002
Identities = 36/119 (30%), Positives = 44/119 (36%), Gaps = 29/119 (24%)
Query: 1987 STPLQAPPPTPPPPPPPPP--------------------PPPPPPPPPPPSAPPQVQL-- 2024
S +A PP P PPPPP PP PPPPPPPP PP
Sbjct: 639 SNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGP 698
Query: 2025 ---PVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADL---TQLCQQQLGLDPN 2077
P LP P+ P P PP L P L L + C ++ ++P+
Sbjct: 699 PPPPPPPPLPNSPA-PPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPS 756
Score = 42.0 bits (97), Expect = 0.011
Identities = 33/105 (31%), Positives = 40/105 (38%), Gaps = 7/105 (6%)
Query: 2334 PAASSGSGTSTPLIPSPKPEP-EKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSD 2392
P SG G+ +P P P P P P P S PP P LP + +
Sbjct: 656 PPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPN 715
Query: 2393 PPQASTAQPQPQPQPPKQPQL-IGRPPSASQTP-----VPSSPLQ 2431
P A P P PP P L G S+SQ P PS P++
Sbjct: 716 PGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMK 760
Score = 40.8 bits (94), Expect = 0.024
Identities = 31/89 (34%), Positives = 36/89 (40%), Gaps = 10/89 (11%)
Query: 3049 LPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSA 3108
LP+ L PP +P ++ LP P L PP + P P L S A
Sbjct: 658 LPSGLGSLSPAPP--MPPVSAGPPLPPPPPPPPPLPPPSSAG---PPPPPPPPPLPNSPA 712
Query: 3109 PTKPLLQTPPPPPPPP---PPPPSSSLSG 3134
P P PPP PPPP PPPP G
Sbjct: 713 PPNP--GGPPPAPPPPGLAPPPPPGLFFG 739
Score = 40.4 bits (93), Expect = 0.032
Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 6/111 (5%)
Query: 2334 PAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDP 2393
P S+G P P P P ++ P P P + P+PP+ G P P + P
Sbjct: 672 PPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPP 731
Query: 2394 PQAST--AQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLP 2442
P Q P++P + PS P+ + +QIS S QN+ P
Sbjct: 732 PPPGLFFGLGSSSSQCPRKPAI---EPSCPMKPLYWTRIQISDRS-QNATP 778
Score = 38.5 bits (88), Expect = 0.12
Identities = 36/151 (23%), Positives = 50/151 (33%), Gaps = 16/151 (10%)
Query: 2290 CYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKN--------AAAPAASSGSG 2341
C + + + ++E ++Q+V K +S + + A P S
Sbjct: 581 CVQTDRETFLKPCESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASN 640
Query: 2342 TSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQA---ST 2398
L P P P P P P+ S P+PP PL PP S+
Sbjct: 641 QQKALPPPPASIP----PPPPLPSGLGSLS-PAPPMPPVSAGPPLPPPPPPPPPLPPPSS 695
Query: 2399 AQPQPQPQPPKQPQLIGRPPSASQTPVPSSP 2429
A P P P PP P P P P P
Sbjct: 696 AGPPPPPPPPPLPNSPAPPNPGGPPPAPPPP 726
Score = 37.7 bits (86), Expect = 0.21
Identities = 30/100 (30%), Positives = 35/100 (35%), Gaps = 7/100 (7%)
Query: 2347 IPSPKPEPEKT-SPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQP 2405
IP P P P S P P P PP P LP S++ PP P P P
Sbjct: 652 IPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPP---PPPPPPLP 708
Query: 2406 QPPKQPQLIGRPPS---ASQTPVPSSPLQISMTSLQNSLP 2442
P P G PP+ P P L + S + P
Sbjct: 709 NSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCP 748
Score = 36.6 bits (83), Expect = 0.46
Identities = 28/84 (33%), Positives = 32/84 (38%), Gaps = 5/84 (5%)
Query: 3048 SLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSN----TLTPPGAGMLGFPTSATSSPAL 3103
+LP +P PP L G+ S P P S PP L P+SA P
Sbjct: 644 ALPPPPASIPP-PPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPP 702
Query: 3104 SLSSAPTKPLLQTPPPPPPPPPPP 3127
P P P PPP PPPP
Sbjct: 703 PPPPLPNSPAPPNPGGPPPAPPPP 726
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 81.3 bits (199), Expect = 2e-14
Identities = 44/78 (56%), Positives = 45/78 (57%), Gaps = 20/78 (25%)
Query: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPP---PPPPPPPPP----- 2009
P PPPPPPLPP P Q S V +P P PPP PP P PPPPPPPPP
Sbjct: 310 PLAPPPPPPLPPGPAQAS----VALP-----PPPGPPPPPPLPSTGPPPPPPPPPLPNQV 360
Query: 2010 PPPPPPPSAPPQVQLPVS 2027
PPPPPPP APP LP S
Sbjct: 361 PPPPPPPPAPP---LPAS 375
Score = 62.0 bits (149), Expect = 1e-08
Identities = 31/66 (46%), Positives = 33/66 (50%), Gaps = 7/66 (10%)
Query: 1947 LYPISPSSPETPPPPP-------PPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPP 1999
L P++P P PP P PPPP PP PP S GP P P Q PPP PPP
Sbjct: 308 LGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPP 367
Query: 2000 PPPPPP 2005
P PP P
Sbjct: 368 PAPPLP 373
Score = 51.6 bits (122), Expect = 1e-05
Identities = 28/61 (45%), Positives = 29/61 (47%), Gaps = 21/61 (34%)
Query: 1952 PSSPETPPPPPPP---PPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008
P P PPPPP P PP PP PP +PN V PPPPPPPP PP
Sbjct: 331 PPPPGPPPPPPLPSTGPPPPPPPP--------PLPNQV----------PPPPPPPPAPPL 372
Query: 2009 P 2009
P
Sbjct: 373 P 373
Score = 43.1 bits (100), Expect = 0.005
Identities = 40/131 (30%), Positives = 48/131 (36%), Gaps = 35/131 (26%)
Query: 3026 SDVLG-LTVQQPGMMDSS------SLHGISL-PTAYPGLPGLPP------VLLPGMNGPS 3071
+ VLG + +PG+ +S S GI L P A P P LPP V LP GP
Sbjct: 278 NSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPP 337
Query: 3072 SLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSS 3131
P P PP P P PPPPPPP PP P+S
Sbjct: 338 PPPPLPSTGPPPPPP---------------------PPPLPNQVPPPPPPPPAPPLPASG 376
Query: 3132 LSGQQTEQQNK 3142
+ N+
Sbjct: 377 FFLASMSEDNR 387
Score = 42.0 bits (97), Expect = 0.011
Identities = 18/35 (51%), Positives = 21/35 (60%), Gaps = 7/35 (20%)
Query: 1949 PISPSSPETPPPPPP-------PPPLPPAPPQPSS 1976
P+ + P PPPPPP PPP PPAPP P+S
Sbjct: 341 PLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPAS 375
Score = 41.2 bits (95), Expect = 0.019
Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)
Query: 2345 PLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQ 2404
PL P P P P P PA+ S PP G P PP ST P P
Sbjct: 310 PLAPPPPP------PLPPGPAQA---SVALPPPPGPPPP---------PPLPSTGPPPPP 351
Query: 2405 PQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQN 2439
P PP Q+ PP P+P+S ++ S N
Sbjct: 352 PPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDN 386
Score = 38.5 bits (88), Expect = 0.12
Identities = 18/44 (40%), Positives = 20/44 (45%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQA 1992
P P P PPPPPPPP PP P + + N T L A
Sbjct: 351 PPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAA 394
Score = 37.4 bits (85), Expect = 0.27
Identities = 21/52 (40%), Positives = 23/52 (44%)
Query: 2004 PPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLP 2055
P PPPPPP PP A V LP P P + P PP L Q+P
Sbjct: 310 PLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVP 361
Score = 35.8 bits (81), Expect = 0.78
Identities = 41/123 (33%), Positives = 45/123 (36%), Gaps = 35/123 (28%)
Query: 2330 NAAAPAASSGSGTSTPL--IPSPKPEPEKTSPKPEYPAEKPKQSD-------PSPPSQGT 2380
+AAAPA+ TPL + E PAE P Q P PP
Sbjct: 266 SAAAPAS-----VETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPP---- 316
Query: 2381 KPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNS 2440
P LP P QAS A P P P PP P L PS P P P L N
Sbjct: 317 -PPLP-----PGPAQASVALPPP-PGPPPPPPL----PSTGPPPPPPPP------PLPNQ 359
Query: 2441 LPP 2443
+PP
Sbjct: 360 VPP 362
Score = 32.3 bits (72), Expect = 8.6
Identities = 24/64 (37%), Positives = 26/64 (40%), Gaps = 6/64 (9%)
Query: 2334 PAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALP-----LAS 2388
PA +S + P P P P P P P P P Q P PP P LP LAS
Sbjct: 323 PAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPP-PAPPLPASGFFLAS 381
Query: 2389 TSSD 2392
S D
Sbjct: 382 MSED 385
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 81.3 bits (199), Expect = 2e-14
Identities = 44/78 (56%), Positives = 45/78 (57%), Gaps = 20/78 (25%)
Query: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPP---PPPPPPPPP----- 2009
P PPPPPPLPP P Q S V +P P PPP PP P PPPPPPPPP
Sbjct: 310 PLAPPPPPPLPPGPAQAS----VALP-----PPPGPPPPPPLPSTGPPPPPPPPPLPNQV 360
Query: 2010 PPPPPPPSAPPQVQLPVS 2027
PPPPPPP APP LP S
Sbjct: 361 PPPPPPPPAPP---LPAS 375
Score = 62.0 bits (149), Expect = 1e-08
Identities = 31/66 (46%), Positives = 33/66 (50%), Gaps = 7/66 (10%)
Query: 1947 LYPISPSSPETPPPPP-------PPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPP 1999
L P++P P PP P PPPP PP PP S GP P P Q PPP PPP
Sbjct: 308 LGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPP 367
Query: 2000 PPPPPP 2005
P PP P
Sbjct: 368 PAPPLP 373
Score = 51.6 bits (122), Expect = 1e-05
Identities = 28/61 (45%), Positives = 29/61 (47%), Gaps = 21/61 (34%)
Query: 1952 PSSPETPPPPPPP---PPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008
P P PPPPP P PP PP PP +PN V PPPPPPPP PP
Sbjct: 331 PPPPGPPPPPPLPSTGPPPPPPPP--------PLPNQV----------PPPPPPPPAPPL 372
Query: 2009 P 2009
P
Sbjct: 373 P 373
Score = 43.1 bits (100), Expect = 0.005
Identities = 40/131 (30%), Positives = 48/131 (36%), Gaps = 35/131 (26%)
Query: 3026 SDVLG-LTVQQPGMMDSS------SLHGISL-PTAYPGLPGLPP------VLLPGMNGPS 3071
+ VLG + +PG+ +S S GI L P A P P LPP V LP GP
Sbjct: 278 NSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPP 337
Query: 3072 SLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSS 3131
P P PP P P PPPPPPP PP P+S
Sbjct: 338 PPPPLPSTGPPPPPP---------------------PPPLPNQVPPPPPPPPAPPLPASG 376
Query: 3132 LSGQQTEQQNK 3142
+ N+
Sbjct: 377 FFLASMSEDNR 387
Score = 42.0 bits (97), Expect = 0.011
Identities = 18/35 (51%), Positives = 21/35 (60%), Gaps = 7/35 (20%)
Query: 1949 PISPSSPETPPPPPP-------PPPLPPAPPQPSS 1976
P+ + P PPPPPP PPP PPAPP P+S
Sbjct: 341 PLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPAS 375
Score = 41.2 bits (95), Expect = 0.019
Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)
Query: 2345 PLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQ 2404
PL P P P P P PA+ S PP G P PP ST P P
Sbjct: 310 PLAPPPPP------PLPPGPAQA---SVALPPPPGPPPP---------PPLPSTGPPPPP 351
Query: 2405 PQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQN 2439
P PP Q+ PP P+P+S ++ S N
Sbjct: 352 PPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDN 386
Score = 38.5 bits (88), Expect = 0.12
Identities = 18/44 (40%), Positives = 20/44 (45%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQA 1992
P P P PPPPPPPP PP P + + N T L A
Sbjct: 351 PPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAA 394
Score = 37.4 bits (85), Expect = 0.27
Identities = 21/52 (40%), Positives = 23/52 (44%)
Query: 2004 PPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLP 2055
P PPPPPP PP A V LP P P + P PP L Q+P
Sbjct: 310 PLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVP 361
Score = 35.8 bits (81), Expect = 0.78
Identities = 41/123 (33%), Positives = 45/123 (36%), Gaps = 35/123 (28%)
Query: 2330 NAAAPAASSGSGTSTPL--IPSPKPEPEKTSPKPEYPAEKPKQSD-------PSPPSQGT 2380
+AAAPA+ TPL + E PAE P Q P PP
Sbjct: 266 SAAAPAS-----VETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPP---- 316
Query: 2381 KPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNS 2440
P LP P QAS A P P P PP P L PS P P P L N
Sbjct: 317 -PPLP-----PGPAQASVALPPP-PGPPPPPPL----PSTGPPPPPPPP------PLPNQ 359
Query: 2441 LPP 2443
+PP
Sbjct: 360 VPP 362
Score = 32.3 bits (72), Expect = 8.6
Identities = 24/64 (37%), Positives = 26/64 (40%), Gaps = 6/64 (9%)
Query: 2334 PAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALP-----LAS 2388
PA +S + P P P P P P P P P Q P PP P LP LAS
Sbjct: 323 PAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPP-PAPPLPASGFFLAS 381
Query: 2389 TSSD 2392
S D
Sbjct: 382 MSED 385
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens]
Length = 505
Score = 80.5 bits (197), Expect = 3e-14
Identities = 49/114 (42%), Positives = 51/114 (44%), Gaps = 37/114 (32%)
Query: 1949 PISPSSPETPPPPPPP----PPLPPA-----PPQPSSMGPVKIP-----NTVSTPLQAPP 1994
P PS PPPPPPP PP PPA PP P S P P + S + PP
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPP 338
Query: 1995 PT-----PPP---------PPPPPP---------PPPPPPPPPPPSAPPQVQLP 2025
P PPP PPPPPP PPPPPPPPPPP PP LP
Sbjct: 339 PNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392
Score = 78.6 bits (192), Expect = 1e-13
Identities = 39/73 (53%), Positives = 41/73 (56%), Gaps = 7/73 (9%)
Query: 1949 PISPSSPETPPPPPPP----PPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP 2004
P PS P PPPPP PP PPA P + GP P +V L P PPPPPPPP
Sbjct: 324 PPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSV---LGVGPVAPPPPPPPP 380
Query: 2005 PPPPPPPPPPPPS 2017
PPP PPPPP PS
Sbjct: 381 PPPGPPPPPGLPS 393
Score = 77.8 bits (190), Expect = 2e-13
Identities = 40/92 (43%), Positives = 45/92 (48%), Gaps = 13/92 (14%)
Query: 1949 PISPSSPETPPPPPPPPPLPPA---PPQPSSMGPVKIPNTVSTPLQAPPPTPP------- 1998
P PS T PPPPPP P PP P+ M P P S+ PPP PP
Sbjct: 311 PPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGP 370
Query: 1999 ---PPPPPPPPPPPPPPPPPPSAPPQVQLPVS 2027
PPPPPPPPPP PPPPP + Q+P +
Sbjct: 371 VAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTT 402
Score = 65.9 bits (159), Expect = 7e-10
Identities = 45/108 (41%), Positives = 51/108 (47%), Gaps = 26/108 (24%)
Query: 1961 PPPPPPL----PPAPPQPSSMGPVKIPNTVSTPLQAPPPTP---PPPPPPPPPP------ 2007
PPPPPP PP PP P + GP P + APPP P P PPPPPP
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGP---PPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVA 333
Query: 2008 -PPPP-----PPPPPSAPPQVQLPVSLDLPLFPSIM-MQPVQHPALPP 2048
PPPP PPPPP+ P S P PS++ + PV P PP
Sbjct: 334 VPPPPPNRMYPPPPPALPSSAP---SGPPPPPPSVLGVGPVAPPPPPP 378
Score = 55.1 bits (131), Expect = 1e-06
Identities = 35/77 (45%), Positives = 37/77 (48%), Gaps = 20/77 (25%)
Query: 1991 QAPPPTPPPP--PPPPPPPP----PPP--------PPPPPSAPPQVQLP------VSLDL 2030
QAPPP PP PPPPPPPP PPP PPPPPS P P S+ +
Sbjct: 275 QAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAV 334
Query: 2031 PLFPSIMMQPVQHPALP 2047
P P M P PALP
Sbjct: 335 PPPPPNRMYPPPPPALP 351
Score = 52.0 bits (123), Expect = 1e-05
Identities = 40/130 (30%), Positives = 52/130 (40%), Gaps = 11/130 (8%)
Query: 2301 ESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPK 2360
E+Q +D T +V+Y +G +A KN A S P P P P + P
Sbjct: 243 EAQLKDR--ETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPP 300
Query: 2361 PEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQ---PPKQPQLIGRP 2417
P P + + + P PPS+ A P P + S A P P P PP P L
Sbjct: 301 P--PPARGRGAPPPPPSRAPTAAPP----PPPPSRPSVAVPPPPPNRMYPPPPPALPSSA 354
Query: 2418 PSASQTPVPS 2427
PS P PS
Sbjct: 355 PSGPPPPPPS 364
Score = 47.4 bits (111), Expect = 3e-04
Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 8/116 (6%)
Query: 3052 AYPGLPGLPPVLLPGMNGPS----SLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSS 3107
A P P P P PS ++P P N PP A P+ P L
Sbjct: 309 APPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGV 368
Query: 3108 APTKPLLQTPPPPPPPPPPPPSSSLSGQQ---TEQQNKESEKKQTKPN-KVKKIKE 3159
P P PPPPPP PPPPP G T NK + Q + ++KK+++
Sbjct: 369 GPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQ 424
Score = 43.1 bits (100), Expect = 0.005
Identities = 29/81 (35%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 3060 PPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPP 3119
PP P GP P P NS PP G P + +P + P PP
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
Query: 3120 PPPP---PPPP---PSSSLSG 3134
PPP PPPP PSS+ SG
Sbjct: 337 PPPNRMYPPPPPALPSSAPSG 357
Score = 37.4 bits (85), Expect = 0.27
Identities = 32/100 (32%), Positives = 37/100 (37%), Gaps = 17/100 (17%)
Query: 2332 AAPAASSGSGTSTPLIPSPKPEPEK--TSPKPEYPAEKPKQSDPSPPS-QGTKPALPLAS 2388
A AA S P + P P P + P P P+ P P PPS G P P
Sbjct: 317 APTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP--- 373
Query: 2389 TSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSS 2428
PP P P P PP P L PS VP++
Sbjct: 374 ----PP---PPPPPPPPGPPPPPGL----PSDGDHQVPTT 402
Score = 34.7 bits (78), Expect = 1.7
Identities = 15/24 (62%), Positives = 15/24 (62%), Gaps = 4/24 (16%)
Query: 3115 QTPPPPPP----PPPPPPSSSLSG 3134
Q PPPPPP PPPPPP SG
Sbjct: 275 QAPPPPPPSRGGPPPPPPPPHNSG 298
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 80.5 bits (197), Expect = 3e-14
Identities = 56/156 (35%), Positives = 65/156 (41%), Gaps = 48/156 (30%)
Query: 1948 YPISPSSPETPPPPPPPPPLPPAPPQP------------SSMGPVKIPNTVSTPLQ---- 1991
Y S SP PPPPPPPPP PP PP P S P+ + + T LQ
Sbjct: 619 YTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQ 678
Query: 1992 -----APPPTP--------------PPPPPPPPPPPPPPPPPPPSAPPQVQ-LPVSLDLP 2031
PPTP PP PPPPPPPPPP P SA Q++ P + LP
Sbjct: 679 HSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLP 738
Query: 2032 LF----PSIMMQPVQH--------PALPPQLALQLP 2055
F P + + VQH P PP + LP
Sbjct: 739 QFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP 774
Score = 70.9 bits (172), Expect = 2e-11
Identities = 30/54 (55%), Positives = 33/54 (61%), Gaps = 4/54 (7%)
Query: 1967 LPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPP 2020
+PP PQP + P T S P PP PPPPPPPPPPPPPPPPP P + P
Sbjct: 606 VPPLSPQPK----IVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAP 655
Score = 70.5 bits (171), Expect = 3e-11
Identities = 46/119 (38%), Positives = 56/119 (47%), Gaps = 22/119 (18%)
Query: 1950 ISPSSPETPPPPPPPPPLP--------PAPPQPS------SMGPVKIPNTVSTPLQAPPP 1995
+ P+ PPPPPPPPP P PAP PS P+KI + V Q PP
Sbjct: 703 VPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI-HQVQHITQVAPP 761
Query: 1996 TPPPPPPPPPPPPPPPPP------PPPSAPPQVQLPVSLDLPLFPSIMMQPV-QHPALP 2047
TPPPPPP P P PP PP P P++ V V+ P P+ + P + PA P
Sbjct: 762 TPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFP 820
Score = 70.5 bits (171), Expect = 3e-11
Identities = 46/126 (36%), Positives = 56/126 (44%), Gaps = 19/126 (15%)
Query: 1946 KLYPISPSSPETPPPPPPPPPLP-PAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP 2004
K++ + + PP PPPPPP+P P PPQ V IP ST AP T PP P
Sbjct: 748 KIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPT 807
Query: 2005 PP---------------PPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQ 2049
PP PP PP PP P PP + S PS + PV P++ Q
Sbjct: 808 PPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPS-PLSPV--PSVVKQ 864
Query: 2050 LALQLP 2055
+A Q P
Sbjct: 865 IASQFP 870
Score = 70.1 bits (170), Expect = 4e-11
Identities = 47/127 (37%), Positives = 54/127 (42%), Gaps = 23/127 (18%)
Query: 1950 ISPSSPETPPPPPP-PPPLPP-APPQPSSMGPVKIPNTVSTPL--QAPPPTPPPP----- 2000
I+ +P TPPPPPP P PLPP APP+P P P+ QA PPTP PP
Sbjct: 755 ITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK 814
Query: 2001 -----------PPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQH---PAL 2046
P PP PP P PPP P P L PS++ Q P
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT 874
Query: 2047 PPQLALQ 2053
PP + Q
Sbjct: 875 PPAMESQ 881
Score = 64.7 bits (156), Expect = 2e-09
Identities = 42/124 (33%), Positives = 49/124 (39%), Gaps = 52/124 (41%)
Query: 1949 PISPSSPETPPPPP-------------------------------PPPPLPPA------P 1971
P SP +P P PPP PPPP PPA
Sbjct: 825 PPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLK 884
Query: 1972 PQPSSMGPVKIPNTVSTP------LQAPPPTPPPPPP------PPPPP---PPPPPPPPP 2016
P P+++ P P + P + P P PPPPP PPPPP P PPPPPPP
Sbjct: 885 PVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPP 944
Query: 2017 SAPP 2020
+A P
Sbjct: 945 TASP 948
Score = 62.4 bits (150), Expect = 8e-09
Identities = 32/81 (39%), Positives = 38/81 (46%), Gaps = 8/81 (9%)
Query: 1959 PPPPPPPPLPPAP--PQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP------PP 2010
PPPP PP + P P P+++ P P + P P P P P PPPPP PP
Sbjct: 870 PPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP 929
Query: 2011 PPPPPPSAPPQVQLPVSLDLP 2031
PPP P APP P + P
Sbjct: 930 PPPSPVPAPPPPPPPTASPTP 950
Score = 59.3 bits (142), Expect = 7e-08
Identities = 37/106 (34%), Positives = 44/106 (41%), Gaps = 29/106 (27%)
Query: 1949 PISPSSP----------ETPPPPPPPP----PLPPAPPQPSSMGPVKI-------PNTVS 1987
P SP SP + PPPP PP PL P P + P + P+++
Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910
Query: 1988 TP---LQAPPPT-----PPPPPPPPPPPPPPPPPPPPSAPPQVQLP 2025
P PPP PPPPP P P PPPPPPP P + P
Sbjct: 911 VPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956
Score = 51.2 bits (121), Expect = 2e-05
Identities = 34/112 (30%), Positives = 45/112 (40%), Gaps = 3/112 (2%)
Query: 2334 PAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDP 2393
PA PL+ P P KT A P + P PP++ +PA P + P
Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK-KQPAFPASYIPPSP 828
Query: 2394 PQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQL 2445
P P P P PKQ +PP + +PVPS QI+ PP +
Sbjct: 829 PTPPV--PVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM 878
Score = 48.9 bits (115), Expect = 9e-05
Identities = 68/288 (23%), Positives = 101/288 (35%), Gaps = 68/288 (23%)
Query: 1947 LYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTP--------- 1997
++P P SP P PPPPPPP P S K T S + PPPTP
Sbjct: 926 VFPPPPPSP-VPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSS 984
Query: 1998 -----PPP-------------PPPPPPPPPPPPPPPPSAPPQ--------VQLP------ 2025
P P PP P PPP+APP+ V LP
Sbjct: 985 SGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQG 1044
Query: 2026 -VSLDLPL-----------FPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLCQQQLG 2073
VS P+ FPS P PP+ L LP ++ + +
Sbjct: 1045 CVSAKAPVLSGRGKDSVVEFPS-PPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV 1103
Query: 2074 LDPNFLRHSQFK----RPRTR-ITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVI 2128
++P + S+ P TR +D ++ +A +I+ P+ + S S +
Sbjct: 1104 VNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQA--EISEQPTMATVVPQVPTSPKSSLSV 1161
Query: 2129 KHWFRNTLFKERQRNKDSPYNFSN------PPITVLEDIRIDPQPTSL 2170
+ F L + QR + + + P ++D+ + P P L
Sbjct: 1162 QPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPEL 1209
Score = 47.8 bits (112), Expect = 2e-04
Identities = 37/129 (28%), Positives = 51/129 (39%), Gaps = 26/129 (20%)
Query: 2327 AAKNAAAPAASSGSGTSTPLIPSP------------KPEPEKTSPKPEYPAEKPKQ--SD 2372
A K A PA+ TP +P P KP P SP P + Q
Sbjct: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872
Query: 2373 PSPPSQGTKPALPL-ASTSSDPPQASTAQPQPQPQ-----------PPKQPQLIGRPPSA 2420
P+PP+ ++P P+ A+ + P A A+P+ QP PP + L+ PP
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932
Query: 2421 SQTPVPSSP 2429
S P P P
Sbjct: 933 SPVPAPPPP 941
Score = 47.8 bits (112), Expect = 2e-04
Identities = 27/78 (34%), Positives = 30/78 (38%), Gaps = 20/78 (25%)
Query: 1942 EAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPP 2001
+A K P S P PPPPP PP PPP+P P P
Sbjct: 899 KAKPKWQPSSIPVPSPDFPPPPPESSLVFPP--------------------PPPSPVPAP 938
Query: 2002 PPPPPPPPPPPPPPPSAP 2019
PPPPPP P P +P
Sbjct: 939 PPPPPPTASPTPDKSGSP 956
Score = 47.4 bits (111), Expect = 3e-04
Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 10/79 (12%)
Query: 1949 PISPSSPETPPP--PPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
P + P+ P P P P PP PP+ S + P P +P P PPPPPPP
Sbjct: 896 PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP--------PPPPSPVPAPPPPPPPTAS 947
Query: 2007 PPPPPPPPPPSAPPQVQLP 2025
P P P + P
Sbjct: 948 PTPDKSGSPGKKTSKTSSP 966
Score = 46.6 bits (109), Expect = 4e-04
Identities = 25/56 (44%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 1983 PNTVSTPLQAPPP---TPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPS 2035
P T P +P P TP P PP PPPPPPPPP PP P L PS
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPS 656
Score = 43.5 bits (101), Expect = 0.004
Identities = 16/23 (69%), Positives = 18/23 (78%)
Query: 3106 SSAPTKPLLQTPPPPPPPPPPPP 3128
+S P+ PL PPPPPPPPPPPP
Sbjct: 621 ASQPSPPLPPPPPPPPPPPPPPP 643
Score = 42.7 bits (99), Expect = 0.006
Identities = 33/134 (24%), Positives = 52/134 (38%), Gaps = 4/134 (2%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAP 3109
P P + P +P P S P + P + + P P SL P
Sbjct: 872 PPTPPAMESQPLKPVPANVAPQSPPAV--KAKPKWQPSSIPVPSPDFPPPPPESSLVFPP 929
Query: 3110 TKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEELEATKPEK 3169
P PPPPPPP P+ SG ++ +K S KP + + ++++ +
Sbjct: 930 PPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQ-RNSSIKSSSGAE 988
Query: 3170 HPK-KEEKISSALS 3182
HP+ K + S +S
Sbjct: 989 HPEPKRPSVDSLVS 1002
Score = 42.4 bits (98), Expect = 0.008
Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 26/101 (25%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQ--NSNTLTPPGAGMLGFPTSATSSPALSLSS 3107
P P P PP LP + PS+ P +T+T S + +L
Sbjct: 635 PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITR---------LQNASQHSGALFK 685
Query: 3108 APTKPLLQT---------------PPPPPPPPPPPPSSSLS 3133
PT P++Q+ PPPPPPPPPP P S+++
Sbjct: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726
Score = 42.0 bits (97), Expect = 0.011
Identities = 18/42 (42%), Positives = 21/42 (50%)
Query: 3094 PTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQ 3135
P +P + +P P PPPPPPPPPPPP L Q
Sbjct: 611 PQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQ 652
Score = 41.6 bits (96), Expect = 0.014
Identities = 24/53 (45%), Positives = 28/53 (52%), Gaps = 4/53 (7%)
Query: 3082 TLTPPGAGMLGFPTSATSS-PALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLS 3133
+L PP + T T+S P+ L P P PPPPPPPPPPPP S S
Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP---PPPPPPPPPPPPPLPSQS 653
Score = 41.2 bits (95), Expect = 0.019
Identities = 56/202 (27%), Positives = 72/202 (35%), Gaps = 26/202 (12%)
Query: 2338 SGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPS-------QGTKPALPLASTS 2390
+ S S PL P P P P P P P P QS PS S T L AS
Sbjct: 620 TASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQH 679
Query: 2391 SDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQC 2450
S P Q Q K PQ++ PP+ P P P + S L P
Sbjct: 680 SGALFKPPTPPVMQSQSVK-PQIL-VPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL 737
Query: 2451 DQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSS 2510
Q + P L++ Q QH+ +A +P P+ P P PL+T
Sbjct: 738 PQFSAPPPPLKIHQV-QHITQVAPP-----TPPPPPPIPAPLPPQAPPKPLVT------- 784
Query: 2511 LTQMPPQASSSHTTAPTTVAAS 2532
P +S+ T AP A+
Sbjct: 785 ----IPAPTSTKTVAPVVTQAA 802
Score = 39.7 bits (91), Expect = 0.054
Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 2333 APAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPS----PPSQGTKPALPLAS 2388
+P S ++ P P P ++ P PA QS P+ P Q + +P
Sbjct: 856 SPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPD 915
Query: 2389 TSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTP 2424
PP++S P P P P P PP+AS TP
Sbjct: 916 FPPPPPESSLVFPPPPPSPVPAPP-PPPPPTASPTP 950
Score = 39.7 bits (91), Expect = 0.054
Identities = 28/113 (24%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 2347 IPSPKPEPEKT-SPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQP 2405
+P+P P P T SP P+ K++ + G KP P + ++S+ P+P
Sbjct: 935 VPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP--PPTPQRNSSIKSSSGAEHPEP 992
Query: 2406 QPPKQPQLIGR--------PPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQC 2450
+ P L+ + PS P P++P + +L P +LQ C
Sbjct: 993 KRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGC 1045
Score = 38.9 bits (89), Expect = 0.092
Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 18/107 (16%)
Query: 2336 ASSGSGTSTPLI-----PSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTS 2390
A + + T P++ P+P P +P +PA S P+PP P LP +
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF 846
Query: 2391 SDPPQASTAQPQPQ---------PQPPKQPQLIGRPPSASQTPVPSS 2428
P S P P P PP P + +P PVP++
Sbjct: 847 CAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP----LKPVPAN 889
Score = 38.1 bits (87), Expect = 0.16
Identities = 60/224 (26%), Positives = 80/224 (35%), Gaps = 37/224 (16%)
Query: 3060 PPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPL------ 3113
P +L+P NG P P T PG+ M A +P+L SAP PL
Sbjct: 699 PQILVPP-NGVVPPPPPPPPPPT---PGSAMAQLKP-APCAPSLPQFSAPPPPLKIHQVQ 753
Query: 3114 --LQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEELEATKPEKHP 3171
Q PP PPPPPP P+ Q + P K + +A P P
Sbjct: 754 HITQVAPPTPPPPPPIPA-----PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP 808
Query: 3172 -----KKEEKISSALSVLGKVVGETHVDPIQLQALQNAIAGDPASFIGGQFLPYFIPGFA 3226
KK+ ++ V P L Q+ A P S + +P + A
Sbjct: 809 PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP--VPSVVKQIA 866
Query: 3227 SYFTPQLPGTVQGGYFPPVCGMESLFPYGPTMPQTLAGLSPGAL 3270
S F P P T PP + L P +P +A SP A+
Sbjct: 867 SQFPP--PPT------PPAMESQPLKP----VPANVAPQSPPAV 898
Score = 35.8 bits (81), Expect = 0.78
Identities = 37/131 (28%), Positives = 49/131 (37%), Gaps = 12/131 (9%)
Query: 2333 APAASSGSGTSTPLIPSPKPEPEK-TSPKPEYPAEKPKQSDPSPPSQGTKPALPL---AS 2388
AP A S S P P + + T P P P P PP KP + + S
Sbjct: 731 APCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTS 790
Query: 2389 TSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQY 2448
T + P + A P P P PP PP+ Q P+S + S + +PP L
Sbjct: 791 TKTVAPVVTQAAP-PTPTPPV-------PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPK 842
Query: 2449 QCDQCTVAFPT 2459
Q C P+
Sbjct: 843 QQSFCAKPPPS 853
Score = 35.4 bits (80), Expect = 1.0
Identities = 28/99 (28%), Positives = 37/99 (37%), Gaps = 17/99 (17%)
Query: 1941 REAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPS--SMGPVKIPNTVS---TPLQAPP- 1994
R + D L E+ P P P APP+P ++ V +P + +AP
Sbjct: 994 RPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVL 1053
Query: 1995 -----------PTPPPPPPPPPPPPPPPPPPPPSAPPQV 2022
P+PP PPPPP P PP P V
Sbjct: 1054 SGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAV 1092
Score = 35.0 bits (79), Expect = 1.3
Identities = 28/109 (25%), Positives = 42/109 (38%), Gaps = 9/109 (8%)
Query: 2330 NAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLAST 2389
+A AP S S PSP + + P PE P P+ S T P + + +
Sbjct: 1047 SAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNP 1106
Query: 2390 SSDPPQASTAQPQPQPQPPK--------QPQLIGRPPSASQTP-VPSSP 2429
+ + P P PK Q ++ +P A+ P VP+SP
Sbjct: 1107 QPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155
Score = 34.7 bits (78), Expect = 1.7
Identities = 33/138 (23%), Positives = 49/138 (35%), Gaps = 10/138 (7%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSA---TSSPALSLS 3106
P A P P +P + P P P++S PP + P T+SP S
Sbjct: 895 PPAVKAKPKWQPSSIP-VPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKS 953
Query: 3107 SAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIK------EE 3160
+P K +T P PPP P + S + + K+ + + V K
Sbjct: 954 GSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSP 1013
Query: 3161 ELEATKPEKHPKKEEKIS 3178
E P P K K++
Sbjct: 1014 SKETLPPPAAPPKPGKLN 1031
Score = 34.3 bits (77), Expect = 2.3
Identities = 31/119 (26%), Positives = 44/119 (36%), Gaps = 9/119 (7%)
Query: 2321 VSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGT 2380
V+ Q+ A A S +P P P PE P P P + P PP
Sbjct: 890 VAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP---PSPVPAPPPPPPPTA 946
Query: 2381 KPALPLASTSSDPPQASTAQP---QPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTS 2436
P P S S + T+ P +P P P + + + S ++ P P P S+ S
Sbjct: 947 SPT-PDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSI--KSSSGAEHPEPKRPSVDSLVS 1002
Score = 33.5 bits (75), Expect = 3.9
Identities = 48/213 (22%), Positives = 64/213 (30%), Gaps = 34/213 (15%)
Query: 2322 SGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTK 2381
S Q+D+ + PA G S ++ S E K + E +S + +
Sbjct: 551 SNQSDSGVSDTQPA---GHVRSQSIVSSVFSEAWKRGTQLE-------ESSKARMESMNR 600
Query: 2382 PALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSL 2441
P L S P+ T QP PP P PP P P PL S
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 2442 PPQLLQYQCDQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPL 2501
P ++Y QN HS L +P P M P
Sbjct: 661 APMFVKYST--------------------ITRLQNASQHSGALFKPPTPPVMQSQSVKP- 699
Query: 2502 MTGQLLGSSLTQMPPQASSSHTTAPTTVAASLK 2534
Q+L +PP P + A LK
Sbjct: 700 ---QILVPPNGVVPPPPPPPPPPTPGSAMAQLK 729
Score = 33.1 bits (74), Expect = 5.1
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 3095 TSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSG 3134
T++ SP L P P PPPPPPPP P S+ +G
Sbjct: 620 TASQPSPPLPPPPPPPPPP-PPPPPPPPPPLPSQSAPSAG 658
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 79.0 bits (193), Expect = 8e-14
Identities = 47/109 (43%), Positives = 52/109 (47%), Gaps = 35/109 (32%)
Query: 1949 PISPSSPETPPPPPPPPPLP----------PAPPQPSSMGPVKIPNTVSTPLQAPPPTP- 1997
P+ P S PPPPPPPPPLP P PP +G + P + PL PPP P
Sbjct: 428 PLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPP---APPL--PPPLPG 482
Query: 1998 -----PPPPPP------PPPPPP--------PPPPPPPSAPPQVQLPVS 2027
PPPPPP PPPPPP PPPPPPP P PV+
Sbjct: 483 SCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVA 531
Score = 73.9 bits (180), Expect = 3e-12
Identities = 47/112 (41%), Positives = 49/112 (43%), Gaps = 28/112 (25%)
Query: 1957 TPPPPPPPP---------PLPPAPPQPSSMGPVKIPNTVSTPLQAP------PPTPPPPP 2001
TPPPPPPPP P PP PP S+G +P T P P PP PP PP
Sbjct: 420 TPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALP-TAPPPPPLPGLGAMAPPAPPLPP 478
Query: 2002 PPP------PPPPPP------PPPPPPSAPPQVQLPVSLDLPLFPSIMMQPV 2041
P P PPPPPP PPPPPP P P PL P PV
Sbjct: 479 PLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPV 530
Score = 60.5 bits (145), Expect = 3e-08
Identities = 41/111 (36%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 1953 SSPETPPPPPPP----PPLPPAPPQPSSMGPVKIPNTVSTP--LQAPPPTPPPPPPPP-- 2004
SSP+ P P P A +P + VS P L+ TPPPPPPPP
Sbjct: 371 SSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLL 430
Query: 2005 -----PPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQL 2050
PPPPPPPPP PS + LP + P P + P LPP L
Sbjct: 431 PGSSAEPPPPPPPPPLPSVGAKA-LPTAPPPPPLPGLGAMAPPAPPLPPPL 480
Score = 43.1 bits (100), Expect = 0.005
Identities = 28/74 (37%), Positives = 29/74 (39%), Gaps = 20/74 (27%)
Query: 1947 LYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
L P P S E PPPPPP P PP PPP P PP
Sbjct: 476 LPPPLPGSCEFLPPPPPPLPGLGCPP--------------------PPPPLLPGMGWGPP 515
Query: 2007 PPPPPPPPPPSAPP 2020
PPPPP P +PP
Sbjct: 516 PPPPPLLPCTCSPP 529
Score = 42.4 bits (98), Expect = 0.008
Identities = 42/160 (26%), Positives = 59/160 (36%), Gaps = 29/160 (18%)
Query: 2989 KVRETVGSQLDREKDYLAPTTV---------RQLMAQQELDRIKKASDVLGLTVQQPGMM 3039
K ++V + LD+ + +P +Q A + + A L V QP +
Sbjct: 355 KAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRAL 414
Query: 3040 DSSSLHGISLPTAYPGLPGLPPVLLPGMNG-------PSSLPGFPQNSNTLTPPGAGMLG 3092
+ + S P P PP LLPG + P LP + PP + G
Sbjct: 415 EQQA----STPPPPP-----PPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPG 465
Query: 3093 FPTSATSSPALSLSSAPTKPLLQTPPPPPP----PPPPPP 3128
A +P L + L PPPP P PPPPPP
Sbjct: 466 LGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPP 505
Score = 38.9 bits (89), Expect = 0.092
Identities = 43/146 (29%), Positives = 52/146 (35%), Gaps = 16/146 (10%)
Query: 2320 TVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYP--------AEKPKQS 2371
+V GQ AA A P + S + + E + ++P P P AE P
Sbjct: 382 SVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPP 441
Query: 2372 DPSP-PSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQP---QLIGRPP---SASQTP 2424
P P PS G K ALP A P P P PP P + + PP P
Sbjct: 442 PPPPLPSVGAK-ALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCP 500
Query: 2425 VPSSPLQISMTSLQNSLPPQLLQYQC 2450
P PL M PP LL C
Sbjct: 501 PPPPPLLPGMGWGPPPPPPPLLPCTC 526
Score = 38.1 bits (87), Expect = 0.16
Identities = 32/91 (35%), Positives = 35/91 (38%), Gaps = 34/91 (37%)
Query: 3048 SLPTAYPG--LPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSL 3105
+LPTA P LPGL + P P LPG + L PP
Sbjct: 453 ALPTAPPPPPLPGLGAMAPPAPPLPPPLPG---SCEFLPPP------------------- 490
Query: 3106 SSAPTKPLLQTPPPPPP--------PPPPPP 3128
P P L PPPPPP PPPPPP
Sbjct: 491 --PPPLPGLGCPPPPPPLLPGMGWGPPPPPP 519
Score = 33.9 bits (76), Expect = 3.0
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 21/146 (14%)
Query: 2306 DSMDAT-DQVVYKHCTVSGQ------TDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTS 2358
D+ + T ++VV + +V G+ A K+ A S G+S +PKP E
Sbjct: 328 DAQECTLEEVVERLLSVKGRPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQ 387
Query: 2359 PKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPP 2418
P E + ++ L ++ + QAST P P P PP P PP
Sbjct: 388 PAAAAACEPVDHAQ-------SESILKVSQPRALEQQAST--PPPPPPPPLLPGSSAEPP 438
Query: 2419 SASQTPVPSSPL-QISMTSLQNSLPP 2443
P P PL + +L + PP
Sbjct: 439 ----PPPPPPPLPSVGAKALPTAPPP 460
Score = 33.9 bits (76), Expect = 3.0
Identities = 15/24 (62%), Positives = 15/24 (62%), Gaps = 3/24 (12%)
Query: 3109 PTKPLL---QTPPPPPPPPPPPPS 3129
P PLL PPPPPPPPP PS
Sbjct: 425 PPPPLLPGSSAEPPPPPPPPPLPS 448
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 79.0 bits (193), Expect = 8e-14
Identities = 47/109 (43%), Positives = 52/109 (47%), Gaps = 35/109 (32%)
Query: 1949 PISPSSPETPPPPPPPPPLP----------PAPPQPSSMGPVKIPNTVSTPLQAPPPTP- 1997
P+ P S PPPPPPPPPLP P PP +G + P + PL PPP P
Sbjct: 428 PLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPP---APPL--PPPLPG 482
Query: 1998 -----PPPPPP------PPPPPP--------PPPPPPPSAPPQVQLPVS 2027
PPPPPP PPPPPP PPPPPPP P PV+
Sbjct: 483 SCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVA 531
Score = 73.9 bits (180), Expect = 3e-12
Identities = 47/112 (41%), Positives = 49/112 (43%), Gaps = 28/112 (25%)
Query: 1957 TPPPPPPPP---------PLPPAPPQPSSMGPVKIPNTVSTPLQAP------PPTPPPPP 2001
TPPPPPPPP P PP PP S+G +P T P P PP PP PP
Sbjct: 420 TPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALP-TAPPPPPLPGLGAMAPPAPPLPP 478
Query: 2002 PPP------PPPPPP------PPPPPPSAPPQVQLPVSLDLPLFPSIMMQPV 2041
P P PPPPPP PPPPPP P P PL P PV
Sbjct: 479 PLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPV 530
Score = 60.5 bits (145), Expect = 3e-08
Identities = 41/111 (36%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 1953 SSPETPPPPPPP----PPLPPAPPQPSSMGPVKIPNTVSTP--LQAPPPTPPPPPPPP-- 2004
SSP+ P P P A +P + VS P L+ TPPPPPPPP
Sbjct: 371 SSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLL 430
Query: 2005 -----PPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQL 2050
PPPPPPPPP PS + LP + P P + P LPP L
Sbjct: 431 PGSSAEPPPPPPPPPLPSVGAKA-LPTAPPPPPLPGLGAMAPPAPPLPPPL 480
Score = 43.1 bits (100), Expect = 0.005
Identities = 28/74 (37%), Positives = 29/74 (39%), Gaps = 20/74 (27%)
Query: 1947 LYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
L P P S E PPPPPP P PP PPP P PP
Sbjct: 476 LPPPLPGSCEFLPPPPPPLPGLGCPP--------------------PPPPLLPGMGWGPP 515
Query: 2007 PPPPPPPPPPSAPP 2020
PPPPP P +PP
Sbjct: 516 PPPPPLLPCTCSPP 529
Score = 42.4 bits (98), Expect = 0.008
Identities = 42/160 (26%), Positives = 59/160 (36%), Gaps = 29/160 (18%)
Query: 2989 KVRETVGSQLDREKDYLAPTTV---------RQLMAQQELDRIKKASDVLGLTVQQPGMM 3039
K ++V + LD+ + +P +Q A + + A L V QP +
Sbjct: 355 KAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRAL 414
Query: 3040 DSSSLHGISLPTAYPGLPGLPPVLLPGMNG-------PSSLPGFPQNSNTLTPPGAGMLG 3092
+ + S P P PP LLPG + P LP + PP + G
Sbjct: 415 EQQA----STPPPPP-----PPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPG 465
Query: 3093 FPTSATSSPALSLSSAPTKPLLQTPPPPPP----PPPPPP 3128
A +P L + L PPPP P PPPPPP
Sbjct: 466 LGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPP 505
Score = 38.9 bits (89), Expect = 0.092
Identities = 43/146 (29%), Positives = 52/146 (35%), Gaps = 16/146 (10%)
Query: 2320 TVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYP--------AEKPKQS 2371
+V GQ AA A P + S + + E + ++P P P AE P
Sbjct: 382 SVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPP 441
Query: 2372 DPSP-PSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQP---QLIGRPP---SASQTP 2424
P P PS G K ALP A P P P PP P + + PP P
Sbjct: 442 PPPPLPSVGAK-ALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCP 500
Query: 2425 VPSSPLQISMTSLQNSLPPQLLQYQC 2450
P PL M PP LL C
Sbjct: 501 PPPPPLLPGMGWGPPPPPPPLLPCTC 526
Score = 38.1 bits (87), Expect = 0.16
Identities = 32/91 (35%), Positives = 35/91 (38%), Gaps = 34/91 (37%)
Query: 3048 SLPTAYPG--LPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSL 3105
+LPTA P LPGL + P P LPG + L PP
Sbjct: 453 ALPTAPPPPPLPGLGAMAPPAPPLPPPLPG---SCEFLPPP------------------- 490
Query: 3106 SSAPTKPLLQTPPPPPP--------PPPPPP 3128
P P L PPPPPP PPPPPP
Sbjct: 491 --PPPLPGLGCPPPPPPLLPGMGWGPPPPPP 519
Score = 33.9 bits (76), Expect = 3.0
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 21/146 (14%)
Query: 2306 DSMDAT-DQVVYKHCTVSGQ------TDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTS 2358
D+ + T ++VV + +V G+ A K+ A S G+S +PKP E
Sbjct: 328 DAQECTLEEVVERLLSVKGRPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQ 387
Query: 2359 PKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPP 2418
P E + ++ L ++ + QAST P P P PP P PP
Sbjct: 388 PAAAAACEPVDHAQ-------SESILKVSQPRALEQQAST--PPPPPPPPLLPGSSAEPP 438
Query: 2419 SASQTPVPSSPL-QISMTSLQNSLPP 2443
P P PL + +L + PP
Sbjct: 439 ----PPPPPPPLPSVGAKALPTAPPP 460
Score = 33.9 bits (76), Expect = 3.0
Identities = 15/24 (62%), Positives = 15/24 (62%), Gaps = 3/24 (12%)
Query: 3109 PTKPLL---QTPPPPPPPPPPPPS 3129
P PLL PPPPPPPPP PS
Sbjct: 425 PPPPLLPGSSAEPPPPPPPPPLPS 448
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 77.8 bits (190), Expect = 2e-13
Identities = 62/209 (29%), Positives = 74/209 (35%), Gaps = 62/209 (29%)
Query: 1949 PISPSSPETPPPPPPPPPLP----PAPPQPSSMGPVKIPNTVSTP-------LQAPPPTP 1997
P P PPP PPPPP P P PP P G P S P APPP P
Sbjct: 309 PPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPP 368
Query: 1998 PPP---------------------PPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSI 2036
PPP PPPPPPPP PPPPP A Q
Sbjct: 369 PPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQ--------------- 413
Query: 2037 MMQPVQHPALPPQLA------LQLPQMDALSADLTQLCQQQLGLDPNFLRHSQFKRPRTR 2090
PA+PP L+ LP + +DL +Q G + + + R
Sbjct: 414 -------PAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQ--GFQLRRVEEQREQEKRDV 464
Query: 2091 ITDDQLKILRAYFDINNSPSEEQIQEMAE 2119
+ +D IL + S SE+ E E
Sbjct: 465 VGNDVATILSRRIAVEYSDSEDDSSEFDE 493
Score = 66.6 bits (161), Expect = 4e-10
Identities = 37/95 (38%), Positives = 41/95 (43%), Gaps = 27/95 (28%)
Query: 1948 YPISPSSPETPPPPPPP----PPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPP 2003
+P P PPPPPPP P LPP P +S P PP PPPPPPP
Sbjct: 355 FPPHPDFAAPPPPPPPPAADYPTLPPPP--------------LSQPTGGAPPPPPPPPPP 400
Query: 2004 PPPPPP---------PPPPPPPSAPPQVQLPVSLD 2029
PPPPP PPP + P+ LP D
Sbjct: 401 GPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSD 435
Score = 54.7 bits (130), Expect = 2e-06
Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 19/116 (16%)
Query: 1948 YPISPSSPETPPPPP-------PPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPP 2000
YP P S P P PPPP + P + G S+ + P P PP
Sbjct: 246 YPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPP 305
Query: 2001 ---PPPP-----PPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048
PP P PPP PPPPPPP P PV P P P P+ PP
Sbjct: 306 LGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTP----PPPSPPSFPP 357
Score = 51.2 bits (121), Expect = 2e-05
Identities = 35/110 (31%), Positives = 42/110 (38%), Gaps = 17/110 (15%)
Query: 3050 PTAYPGLPGLPPVL---LPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLS 3106
P G+P PP + PG P S P FP + + PP PA
Sbjct: 326 PPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPP---------PPPPPPAADYP 376
Query: 3107 SAPTKPLLQT-----PPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKP 3151
+ P PL Q PPPPPPPPP PP +G + TKP
Sbjct: 377 TLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKP 426
Score = 44.7 bits (104), Expect = 0.002
Identities = 67/312 (21%), Positives = 109/312 (34%), Gaps = 77/312 (24%)
Query: 2162 RIDPQPTSLEHYKSDASFSKRSSRTRFTDYQLRVLQDFFDTNAYP--------------- 2206
R+ + T L+ + + S ++R F ++ Q FD N+ P
Sbjct: 74 RLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQD-QKLFDRNSLPVPVLETYNTCDTPPP 132
Query: 2207 -------KDDEIEQLSTVLNLPTRVIVVW----FQNARQKARKSYENQAETKDNEKRELT 2255
+DD E L + P+ +W Q+ + ++ +++ E KDN R
Sbjct: 133 LNNLTPYRDDGKEALKFYTD-PSYFFDLWKEKMLQDTKDIMKEKRKHRKEKKDNPNRGNV 191
Query: 2256 NERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVV 2315
N R I+T +++ K F + + + +V
Sbjct: 192 NPRKIKTRKEEWEKMKMGQEF----------------------VESKEKLGTSGYPPTLV 229
Query: 2316 YKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKP---EYPAEK----- 2367
Y++ ++ + ++ P S S +S PSP + P P YP +
Sbjct: 230 YQNGSIGCVENVDASSYPPPPQSDSASS----PSPSFSEDNLPPPPAEFSYPVDNQRGSG 285
Query: 2368 ---PKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPP------ 2418
PK+S PS PA PL S PP P PP P +IG PP
Sbjct: 286 LAGPKRSSVVSPSH-PPPAPPLGS----PPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVG 340
Query: 2419 -SASQTPVPSSP 2429
+ TP P SP
Sbjct: 341 FGSPGTPPPPSP 352
Score = 44.3 bits (103), Expect = 0.002
Identities = 31/106 (29%), Positives = 37/106 (34%), Gaps = 1/106 (0%)
Query: 2341 GTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQ 2400
G + P P P P P P P P P PPS + P P + PP A
Sbjct: 315 GFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAAD 374
Query: 2401 PQPQPQPPKQPQLIGRPPSASQTPVPS-SPLQISMTSLQNSLPPQL 2445
P PP G PP P P P + Q ++PP L
Sbjct: 375 YPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPL 420
Score = 42.7 bits (99), Expect = 0.006
Identities = 32/111 (28%), Positives = 41/111 (36%), Gaps = 11/111 (9%)
Query: 2341 GTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQ 2400
G +P P P P P P P++ A P P PP P LP PP +
Sbjct: 340 GFGSPGTPPP-PSPPSFPPHPDFAAPPP----PPPPPAADYPTLP------PPPLSQPTG 388
Query: 2401 PQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQCD 2451
P P PP P PP P+ P +S T+ S P + + D
Sbjct: 389 GAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSD 439
Score = 36.6 bits (83), Expect = 0.46
Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 21/87 (24%)
Query: 3065 PGMNGPSSLPGFPQNSNTLTPP------------GAGMLGFPTSATSSPALSLSSAPTKP 3112
P + +S P + + L PP G+G+ G S+ SP S P P
Sbjct: 249 PPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSP----SHPPPAP 304
Query: 3113 LLQTPPPP-----PPPPPPPPSSSLSG 3134
L +PP P PPP PPPP + G
Sbjct: 305 PLGSPPGPKPGFAPPPAPPPPPPPMIG 331
Score = 35.8 bits (81), Expect = 0.78
Identities = 22/69 (31%), Positives = 26/69 (37%), Gaps = 4/69 (5%)
Query: 3064 LPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPP 3123
LP S P Q + L P + P+ +P L P P PPPPP
Sbjct: 267 LPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPP 326
Query: 3124 PP----PPP 3128
PP PPP
Sbjct: 327 PPMIGIPPP 335
Score = 35.4 bits (80), Expect = 1.0
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 18/74 (24%)
Query: 3071 SSLPGFPQNSNTLTP---PGAGMLGFPTSATSSPALSLSSAPTKP---LLQTPPPPPP-- 3122
S L G P+ S+ ++P P A LG P P + AP P ++ PPPPPP
Sbjct: 284 SGLAG-PKRSSVVSPSHPPPAPPLGSPPGP--KPGFAPPPAPPPPPPPMIGIPPPPPPVG 340
Query: 3123 -------PPPPPPS 3129
PPP PPS
Sbjct: 341 FGSPGTPPPPSPPS 354
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 76.6 bits (187), Expect = 4e-13
Identities = 47/145 (32%), Positives = 60/145 (41%), Gaps = 29/145 (20%)
Query: 1935 KFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPP 1994
K ++ +A ++ +S ++ PP P P+PPAPP P G + P PP
Sbjct: 541 KLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPP 600
Query: 1995 PTPPPPPPPPPPP-----------------PPPPP-------PPPPSAPPQVQLPVSLDL 2030
P PPPPPPPPP P PPPP PPPP P V +P L
Sbjct: 601 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 660
Query: 2031 PLFPSIMMQP-----VQHPALPPQL 2050
P +I P + P PP L
Sbjct: 661 PGGTAIPPPPPLPGSARIPPPPPPL 685
Score = 73.9 bits (180), Expect = 3e-12
Identities = 57/167 (34%), Positives = 62/167 (37%), Gaps = 60/167 (35%)
Query: 1952 PSSPETPPPPP---------------------PPPPL------PPAPPQPSSMG---PVK 1981
P P PPPPP PPPPL PP PP P +G P
Sbjct: 600 PPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS 659
Query: 1982 IPNTVSTPLQAPPPTP-----PPPPPP-------PPPPPP-------PPPPPP----PSA 2018
+P T + PPP P PPPPPP PPPPPP PPPPPP P
Sbjct: 660 LPG--GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGI 717
Query: 2019 PPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLT 2065
PP P +P P M P PP +P L LT
Sbjct: 718 PPPPPFPGGPGIPPPPPGMGMPP-----PPPFGFGVPAAPVLPFGLT 759
Score = 70.1 bits (170), Expect = 4e-11
Identities = 59/187 (31%), Positives = 74/187 (39%), Gaps = 21/187 (11%)
Query: 1951 SPSSPETPPPPPPPPPLP-------PAPPQPSSMG----PVKIPNTVSTPLQAPPPTP-- 1997
SPSS PPPPPLP P PP P S G P +P P PPP P
Sbjct: 656 SPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP-PPPPPLPGG 714
Query: 1998 ---PPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQL 2054
PPPPP P P PPPPP PP P +P P + P++ L+
Sbjct: 715 PGIPPPPPFPGGPGIPPPPPGMGMPPPP--PFGFGVPAAPVLPFGLTPKKLYKPEVQLRR 772
Query: 2055 PQMDALSA-DLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQ 2113
P L A DL+Q C + F + F + T Q K +A D ++
Sbjct: 773 PNWSKLVAEDLSQDCFWTKVKEDRFENNELFAK-LTLTFSAQTKTSKAKKDQEGGEEKKS 831
Query: 2114 IQEMAEK 2120
+Q+ K
Sbjct: 832 VQKKKVK 838
Score = 61.6 bits (148), Expect = 1e-08
Identities = 44/136 (32%), Positives = 53/136 (38%), Gaps = 28/136 (20%)
Query: 1937 ARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPT 1996
A+ +E D ++ S PP P P PP P G T+ P AP +
Sbjct: 540 AKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGD---SGTIIPPPPAPGDS 596
Query: 1997 PPPPPPPPPPPPPPP--------------------PPPPPSA----PPQVQLPVSLDLPL 2032
PPPPPPPPPPPPP PPPP S PP LP + +P
Sbjct: 597 TTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP- 655
Query: 2033 FPSIMMQPVQHPALPP 2048
PS + P PP
Sbjct: 656 SPSSLPGGTAIPPPPP 671
Score = 46.6 bits (109), Expect = 4e-04
Identities = 52/216 (24%), Positives = 79/216 (36%), Gaps = 26/216 (12%)
Query: 2233 RQKARKSYENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIF-------DLITH 2285
+ K KS AE + ELT +Q + KK F + D +
Sbjct: 462 KTKVEKSEAKAAELEKKLDSELTARH-----ELQVEMKKMESDFEQKLQDLQGEKDALHS 516
Query: 2286 QKKQCYKDEDDDAQDESQ--------TEDSMDATDQVV-YKHCTVSGQTDAAKNAAAPAA 2336
+K+Q ++ D + SQ T++ DA ++ ++ A P A
Sbjct: 517 EKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 576
Query: 2337 SSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQA 2396
G S +IP P + T+P P P P P + P+LP + S PP
Sbjct: 577 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPL 636
Query: 2397 STAQPQPQPQPPKQPQLIGRPPSAS---QTPVPSSP 2429
S P PP P+ +G P +S T +P P
Sbjct: 637 S--GDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPP 670
Score = 45.1 bits (105), Expect = 0.001
Identities = 30/90 (33%), Positives = 37/90 (41%), Gaps = 31/90 (34%)
Query: 3039 MDSSSLHGISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSAT 3098
M S S I++P + P +PP P P +S T+ PP
Sbjct: 553 MASLSAAAITVPPSVPSRAPVPPA-----------PPLPGDSGTIIPP------------ 589
Query: 3099 SSPALSLSSAPTKPLLQTPPPPPPPPPPPP 3128
PA S+ P PPPPPPPPPPPP
Sbjct: 590 -PPAPGDSTTP-------PPPPPPPPPPPP 611
Score = 42.7 bits (99), Expect = 0.006
Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 21/102 (20%)
Query: 3054 PGLPGLPPVLLPG---MNGPSSLPGF-------PQNSNTLTPPGAGM---LGFPTSATSS 3100
P P PP LPG ++ P SLPG P + + PP + +G P+ ++
Sbjct: 602 PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 661
Query: 3101 PALSLSSAPTKP-LLQTPPPPPP-------PPPPPPSSSLSG 3134
++ P P + PPPPPP PPPPPP +G
Sbjct: 662 GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 703
Score = 42.7 bits (99), Expect = 0.006
Identities = 30/90 (33%), Positives = 37/90 (41%), Gaps = 16/90 (17%)
Query: 3046 GISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSL 3105
GI P++ PG +PP P + G + +P P PP G G P P +
Sbjct: 653 GIPSPSSLPGGTAIPPP--PPLPGSARIPPPP-------PPLPGSAGIPPPPPPLPGEAG 703
Query: 3106 SSAPTKPLLQTPPPPPPPP-------PPPP 3128
P PL P PPPPP PPPP
Sbjct: 704 MPPPPPPLPGGPGIPPPPPFPGGPGIPPPP 733
Score = 36.6 bits (83), Expect = 0.46
Identities = 58/218 (26%), Positives = 78/218 (35%), Gaps = 42/218 (19%)
Query: 3037 GMMDSSSLHGISLPTAYPGLPGL-----PPVLLPGMNG-PSSLPGFPQNSNTLTPPGAGM 3090
G+ SSL G + P LPG PP LPG G P P P + + PP +
Sbjct: 653 GIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG-MPPPPPPL 711
Query: 3091 LGFPTSATSSPALSLSSAPTKPLLQTPPPPPP-PPPPPPSSSLSGQQTEQQNKESEKKQT 3149
G P P P P PPPPP P + L T ++ + E +
Sbjct: 712 PGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLR 771
Query: 3150 KPNKVK-------------KIKEEELE--------------ATKPEKHPKKEEKISSALS 3182
+PN K K+KE+ E TK K K +E S
Sbjct: 772 RPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKS 831
Query: 3183 VLGKVVGETHVDPIQLQALQNAIAGDPASFIGGQFLPY 3220
V K V E L+ L + A + + F+G +PY
Sbjct: 832 VQKKKVKE-------LKVLDSKTAQNLSIFLGSFRMPY 862
Score = 34.3 bits (77), Expect = 2.3
Identities = 27/87 (31%), Positives = 31/87 (35%), Gaps = 17/87 (19%)
Query: 2347 IPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQP- 2405
IPSP P T+ P P + P PP PL ++ PP P P P
Sbjct: 654 IPSPSSLPGGTAIPPPPPLPGSARIPPPPP--------PLPGSAGIPPP-----PPPLPG 700
Query: 2406 ---QPPKQPQLIGRPPSASQTPVPSSP 2429
PP P L G P P P P
Sbjct: 701 EAGMPPPPPPLPGGPGIPPPPPFPGGP 727
Score = 32.3 bits (72), Expect = 8.6
Identities = 29/100 (29%), Positives = 33/100 (33%), Gaps = 38/100 (38%)
Query: 1990 LQAPPPTPPPPPPPPPPPP------------------------PPPPPPPPSAPPQVQLP 2025
L A T PP P P P PPPPPPPP PP +
Sbjct: 556 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGG 615
Query: 2026 VSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLT 2065
V + P P+LP A+ P LS D T
Sbjct: 616 VCISSP------------PSLPGGTAISPP--PPLSGDAT 641
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 76.6 bits (187), Expect = 4e-13
Identities = 47/145 (32%), Positives = 60/145 (41%), Gaps = 29/145 (20%)
Query: 1935 KFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPP 1994
K ++ +A ++ +S ++ PP P P+PPAPP P G + P PP
Sbjct: 550 KLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPP 609
Query: 1995 PTPPPPPPPPPPP-----------------PPPPP-------PPPPSAPPQVQLPVSLDL 2030
P PPPPPPPPP P PPPP PPPP P V +P L
Sbjct: 610 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 669
Query: 2031 PLFPSIMMQP-----VQHPALPPQL 2050
P +I P + P PP L
Sbjct: 670 PGGTAIPPPPPLPGSARIPPPPPPL 694
Score = 73.9 bits (180), Expect = 3e-12
Identities = 57/167 (34%), Positives = 62/167 (37%), Gaps = 60/167 (35%)
Query: 1952 PSSPETPPPPP---------------------PPPPL------PPAPPQPSSMG---PVK 1981
P P PPPPP PPPPL PP PP P +G P
Sbjct: 609 PPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS 668
Query: 1982 IPNTVSTPLQAPPPTP-----PPPPPP-------PPPPPP-------PPPPPP----PSA 2018
+P T + PPP P PPPPPP PPPPPP PPPPPP P
Sbjct: 669 LPG--GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGI 726
Query: 2019 PPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLT 2065
PP P +P P M P PP +P L LT
Sbjct: 727 PPPPPFPGGPGIPPPPPGMGMPP-----PPPFGFGVPAAPVLPFGLT 768
Score = 70.1 bits (170), Expect = 4e-11
Identities = 59/187 (31%), Positives = 74/187 (39%), Gaps = 21/187 (11%)
Query: 1951 SPSSPETPPPPPPPPPLP-------PAPPQPSSMG----PVKIPNTVSTPLQAPPPTP-- 1997
SPSS PPPPPLP P PP P S G P +P P PPP P
Sbjct: 665 SPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP-PPPPPLPGG 723
Query: 1998 ---PPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQL 2054
PPPPP P P PPPPP PP P +P P + P++ L+
Sbjct: 724 PGIPPPPPFPGGPGIPPPPPGMGMPPPP--PFGFGVPAAPVLPFGLTPKKLYKPEVQLRR 781
Query: 2055 PQMDALSA-DLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQ 2113
P L A DL+Q C + F + F + T Q K +A D ++
Sbjct: 782 PNWSKLVAEDLSQDCFWTKVKEDRFENNELFAK-LTLTFSAQTKTSKAKKDQEGGEEKKS 840
Query: 2114 IQEMAEK 2120
+Q+ K
Sbjct: 841 VQKKKVK 847
Score = 61.6 bits (148), Expect = 1e-08
Identities = 44/136 (32%), Positives = 53/136 (38%), Gaps = 28/136 (20%)
Query: 1937 ARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPT 1996
A+ +E D ++ S PP P P PP P G T+ P AP +
Sbjct: 549 AKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGD---SGTIIPPPPAPGDS 605
Query: 1997 PPPPPPPPPPPPPPP--------------------PPPPPSA----PPQVQLPVSLDLPL 2032
PPPPPPPPPPPPP PPPP S PP LP + +P
Sbjct: 606 TTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP- 664
Query: 2033 FPSIMMQPVQHPALPP 2048
PS + P PP
Sbjct: 665 SPSSLPGGTAIPPPPP 680
Score = 46.6 bits (109), Expect = 4e-04
Identities = 52/216 (24%), Positives = 79/216 (36%), Gaps = 26/216 (12%)
Query: 2233 RQKARKSYENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIF-------DLITH 2285
+ K KS AE + ELT +Q + KK F + D +
Sbjct: 471 KTKVEKSEAKAAELEKKLDSELTARH-----ELQVEMKKMESDFEQKLQDLQGEKDALHS 525
Query: 2286 QKKQCYKDEDDDAQDESQ--------TEDSMDATDQVV-YKHCTVSGQTDAAKNAAAPAA 2336
+K+Q ++ D + SQ T++ DA ++ ++ A P A
Sbjct: 526 EKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 585
Query: 2337 SSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQA 2396
G S +IP P + T+P P P P P + P+LP + S PP
Sbjct: 586 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPL 645
Query: 2397 STAQPQPQPQPPKQPQLIGRPPSAS---QTPVPSSP 2429
S P PP P+ +G P +S T +P P
Sbjct: 646 S--GDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPP 679
Score = 45.1 bits (105), Expect = 0.001
Identities = 30/90 (33%), Positives = 37/90 (41%), Gaps = 31/90 (34%)
Query: 3039 MDSSSLHGISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSAT 3098
M S S I++P + P +PP P P +S T+ PP
Sbjct: 562 MASLSAAAITVPPSVPSRAPVPPA-----------PPLPGDSGTIIPP------------ 598
Query: 3099 SSPALSLSSAPTKPLLQTPPPPPPPPPPPP 3128
PA S+ P PPPPPPPPPPPP
Sbjct: 599 -PPAPGDSTTP-------PPPPPPPPPPPP 620
Score = 42.7 bits (99), Expect = 0.006
Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 21/102 (20%)
Query: 3054 PGLPGLPPVLLPG---MNGPSSLPGF-------PQNSNTLTPPGAGM---LGFPTSATSS 3100
P P PP LPG ++ P SLPG P + + PP + +G P+ ++
Sbjct: 611 PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 670
Query: 3101 PALSLSSAPTKP-LLQTPPPPPP-------PPPPPPSSSLSG 3134
++ P P + PPPPPP PPPPPP +G
Sbjct: 671 GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 712
Score = 42.7 bits (99), Expect = 0.006
Identities = 30/90 (33%), Positives = 37/90 (41%), Gaps = 16/90 (17%)
Query: 3046 GISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSL 3105
GI P++ PG +PP P + G + +P P PP G G P P +
Sbjct: 662 GIPSPSSLPGGTAIPPP--PPLPGSARIPPPP-------PPLPGSAGIPPPPPPLPGEAG 712
Query: 3106 SSAPTKPLLQTPPPPPPPP-------PPPP 3128
P PL P PPPPP PPPP
Sbjct: 713 MPPPPPPLPGGPGIPPPPPFPGGPGIPPPP 742
Score = 36.6 bits (83), Expect = 0.46
Identities = 58/218 (26%), Positives = 78/218 (35%), Gaps = 42/218 (19%)
Query: 3037 GMMDSSSLHGISLPTAYPGLPGL-----PPVLLPGMNG-PSSLPGFPQNSNTLTPPGAGM 3090
G+ SSL G + P LPG PP LPG G P P P + + PP +
Sbjct: 662 GIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG-MPPPPPPL 720
Query: 3091 LGFPTSATSSPALSLSSAPTKPLLQTPPPPPP-PPPPPPSSSLSGQQTEQQNKESEKKQT 3149
G P P P P PPPPP P + L T ++ + E +
Sbjct: 721 PGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLR 780
Query: 3150 KPNKVK-------------KIKEEELE--------------ATKPEKHPKKEEKISSALS 3182
+PN K K+KE+ E TK K K +E S
Sbjct: 781 RPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKS 840
Query: 3183 VLGKVVGETHVDPIQLQALQNAIAGDPASFIGGQFLPY 3220
V K V E L+ L + A + + F+G +PY
Sbjct: 841 VQKKKVKE-------LKVLDSKTAQNLSIFLGSFRMPY 871
Score = 34.3 bits (77), Expect = 2.3
Identities = 27/87 (31%), Positives = 31/87 (35%), Gaps = 17/87 (19%)
Query: 2347 IPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQP- 2405
IPSP P T+ P P + P PP PL ++ PP P P P
Sbjct: 663 IPSPSSLPGGTAIPPPPPLPGSARIPPPPP--------PLPGSAGIPPP-----PPPLPG 709
Query: 2406 ---QPPKQPQLIGRPPSASQTPVPSSP 2429
PP P L G P P P P
Sbjct: 710 EAGMPPPPPPLPGGPGIPPPPPFPGGP 736
Score = 32.3 bits (72), Expect = 8.6
Identities = 29/100 (29%), Positives = 33/100 (33%), Gaps = 38/100 (38%)
Query: 1990 LQAPPPTPPPPPPPPPPPP------------------------PPPPPPPPSAPPQVQLP 2025
L A T PP P P P PPPPPPPP PP +
Sbjct: 565 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGG 624
Query: 2026 VSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLT 2065
V + P P+LP A+ P LS D T
Sbjct: 625 VCISSP------------PSLPGGTAISPP--PPLSGDAT 650
>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
[Homo sapiens]
Length = 355
Score = 76.6 bits (187), Expect = 4e-13
Identities = 40/97 (41%), Positives = 44/97 (45%), Gaps = 34/97 (35%)
Query: 1951 SPSSPETPPPP------------------PPPPPLPPAPPQPSSMGPVKIPNTVSTPLQA 1992
+P P T PPP PPP PLPP PP
Sbjct: 235 TPPPPTTRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPR--------------- 279
Query: 1993 PPPTPPPPPPPPPPP-PPPPPPPPPSAPPQVQLPVSL 2028
PPP+PPPPPPPPP P PPPPPPPPP+ +LP L
Sbjct: 280 PPPSPPPPPPPPPSPLPPPPPPPPPTPSSTTKLPQGL 316
Score = 58.5 bits (140), Expect = 1e-07
Identities = 29/73 (39%), Positives = 30/73 (41%), Gaps = 23/73 (31%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008
P P P P P PPP PP PPP PPP P PPPPPP
Sbjct: 265 PPRPLPPRPPAAQPRPPPSPP-----------------------PPPPPPPSPLPPPPPP 301
Query: 2009 PPPPPPPPSAPPQ 2021
PPP P + PQ
Sbjct: 302 PPPTPSSTTKLPQ 314
Score = 52.0 bits (123), Expect = 1e-05
Identities = 25/61 (40%), Positives = 27/61 (44%), Gaps = 23/61 (37%)
Query: 1947 LYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
L P P++ PPP PPPPP PP P P PPPPPPPPP
Sbjct: 269 LPPRPPAAQPRPPPSPPPPPPPP-----------------------PSPLPPPPPPPPPT 305
Query: 2007 P 2007
P
Sbjct: 306 P 306
Score = 46.2 bits (108), Expect = 6e-04
Identities = 23/42 (54%), Positives = 25/42 (59%), Gaps = 5/42 (11%)
Query: 1949 PISPSSPETPPPPPP---PPPLPPAPPQPSSMGPVKIPNTVS 1987
P P SP PPPPPP PPP PP PP PSS K+P +S
Sbjct: 278 PRPPPSPPPPPPPPPSPLPPPPPPPPPTPSS--TTKLPQGLS 317
Score = 42.7 bits (99), Expect = 0.006
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 3060 PPVLLPGMNGPSS--LPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTP 3117
PP + P + P S LP + Q PP + P +A P S P P P
Sbjct: 243 PPPIRPPFSHPLSAHLPWYFQ------PPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLP 296
Query: 3118 PPPPPPPPPPPSSS 3131
PPPPPPPP P S++
Sbjct: 297 PPPPPPPPTPSSTT 310
Score = 42.4 bits (98), Expect = 0.008
Identities = 31/106 (29%), Positives = 41/106 (38%), Gaps = 17/106 (16%)
Query: 1981 KIPNTVSTPLQAPPPTPPPPPPPP-----------------PPPPPPPPPPPPSAPPQVQ 2023
KI + +Q+ P PP PPP PPP P PP PP+A P+
Sbjct: 222 KIGSNALRMIQSATPPPPTTRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPP 281
Query: 2024 LPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLCQ 2069
P PS + P P P +LPQ + + L QL +
Sbjct: 282 PSPPPPPPPPPSPLPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIE 327
Score = 39.3 bits (90), Expect = 0.071
Identities = 31/94 (32%), Positives = 35/94 (37%), Gaps = 12/94 (12%)
Query: 2336 ASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQ 2395
AS + +I S P P T P P P S P P PL PP+
Sbjct: 220 ASKIGSNALRMIQSATPPPPTTRPPPIRPPFSHPLS-AHLPWYFQPPPRPL------PPR 272
Query: 2396 ASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSP 2429
AQP+P P PP P PP S P P P
Sbjct: 273 PPAAQPRPPPSPPPPP-----PPPPSPLPPPPPP 301
Score = 37.0 bits (84), Expect = 0.35
Identities = 16/25 (64%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Query: 3109 PTKPLLQT-PPPPPPPPPPPPSSSL 3132
P P Q PPP PPPPPPPP S L
Sbjct: 271 PRPPAAQPRPPPSPPPPPPPPPSPL 295
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 76.3 bits (186), Expect = 5e-13
Identities = 46/123 (37%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 1954 SPETPPPPPP--PPPLPPAPP--QPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPP 2009
+P +PPP PP P PPA P PS+ P + P +++ P PP+PP PP P P
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722
Query: 2010 PPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLA---LQLPQMDALSADLTQ 2066
PP PPP A P +Q+P S P P + P +PP LA LQ+P S ++
Sbjct: 723 PPQAPPPLAAPPLQVPPS--PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
Query: 2067 LCQ 2069
L +
Sbjct: 781 LAK 783
Score = 75.9 bits (185), Expect = 7e-13
Identities = 51/122 (41%), Positives = 60/122 (49%), Gaps = 15/122 (12%)
Query: 1949 PISPSSPETPPPPPPP----PPL--PPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPP 2002
P+SPS+ TPP PP PPL PP+PP M P P + P A PP PP P
Sbjct: 684 PVSPSA--TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741
Query: 2003 PPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFP--SIMMQPVQHPALPPQL--ALQLPQMD 2058
P PP P PPP PP + P L +P P S+ M P+ P PPQ AL P +
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAP-PLQVPPSPPASLPMSPLAKP--PPQAPPALATPPLQ 798
Query: 2059 AL 2060
AL
Sbjct: 799 AL 800
Score = 73.2 bits (178), Expect = 4e-12
Identities = 48/128 (37%), Positives = 53/128 (41%), Gaps = 22/128 (17%)
Query: 1952 PSSPETPPPPPPPPPL-------PPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP 2004
P SP PPP PPPL PP+PP M P P PL A PP PP PP
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
Query: 2005 PPPPPPPPPPPPSAPPQVQLPVSLDLPLFP-------------SIMMQPV--QHPALPPQ 2049
P P PPP APP + P LP P S+ M P+ P PP
Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 834
Query: 2050 LALQLPQM 2057
LA L Q+
Sbjct: 835 LAAPLLQV 842
Score = 68.6 bits (166), Expect = 1e-10
Identities = 45/113 (39%), Positives = 54/113 (47%), Gaps = 21/113 (18%)
Query: 1949 PISPSSP-ETPPPPPPP----PPL--PPAPPQPSSMGPV-----KIPNTVSTPLQAPPPT 1996
P P SP TPPP PP PPL PP+PP + P+ + PN ++ L P +
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 1997 PPPPPPPPPP-PPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048
PPP PP P PP PP PSA P Q P PS+ P+Q P PP
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAP--------PSLAAPPLQVPPSPP 711
Score = 65.5 bits (158), Expect = 9e-10
Identities = 47/139 (33%), Positives = 59/139 (42%), Gaps = 10/139 (7%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008
P++ ETPP P P P APP P + P + P++++TP PP PP PP
Sbjct: 552 PLTTPHLETPPCPAPCPL--QAPPSPLTTPPPETPSSIATP----PPQAPPALASPPLQG 605
Query: 2009 PPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLC 2068
P PP P A P Q P L LP + P PA PP L P A +A L
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALP----PLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661
Query: 2069 QQQLGLDPNFLRHSQFKRP 2087
Q P+ + F P
Sbjct: 662 QAPFSPPPSPPVQAPFSPP 680
Score = 63.2 bits (152), Expect = 5e-09
Identities = 44/129 (34%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 1950 ISPSSPETPPPPPPPPPLP-----PAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP 2004
++P S +TPP PPL PP ++ P+ P+ + P AP P PP P
Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLT 577
Query: 2005 PPPPPPP---PPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLA---LQLPQMD 2058
PPP P PPP APP + P LP P + P PP LA LQ P
Sbjct: 578 TPPPETPSSIATPPPQAPPALASPPLQGLP-SPPLSPLATPPPQAPPXLALPPLQAPPSP 636
Query: 2059 ALSADLTQL 2067
S L+ L
Sbjct: 637 PASPPLSPL 645
Score = 61.2 bits (147), Expect = 2e-08
Identities = 41/119 (34%), Positives = 49/119 (41%), Gaps = 8/119 (6%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP---P 2005
P P+SP P PPP +PP P P+++P + L P PPP PP
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAP----PLQVPPSPPASLPMSPLAKPPPQAPPALAT 794
Query: 2006 PPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADL 2064
PP P PP S P Q S LP+ P P P L L LQ+P S L
Sbjct: 795 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTL 852
Score = 60.1 bits (144), Expect = 4e-08
Identities = 54/184 (29%), Positives = 75/184 (40%), Gaps = 21/184 (11%)
Query: 1941 REAYDKLYPISPSSPETPPPP-----PPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPP 1995
++A L P+S S TP P P PPP A P P+++ P ++TPL PP
Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP---PLATPLPLAPP 346
Query: 1996 TPPPPPP------PPPPPPPPPPP----PPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPA 2045
+P PP PP PP PP PP APP +Q + +P S+ +Q P
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP--HSLTSPSLQAPP 404
Query: 2046 LPPQLALQLPQMDALSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDI 2105
P L+ L +L + Q L + P + S R T L+A +
Sbjct: 405 SPLALS-SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463
Query: 2106 NNSP 2109
SP
Sbjct: 464 PASP 467
Score = 52.4 bits (124), Expect = 8e-06
Identities = 60/213 (28%), Positives = 74/213 (34%), Gaps = 23/213 (10%)
Query: 2327 AAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPS--PPSQGTKPAL 2384
A + AP A + P P P P + P P P + PS PPS P
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Query: 2385 PLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPP--------SASQTPVPSSPLQISMTS 2436
S + PP + +A P PQ PP + PP S S TP P P ++
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 2437 LQ------NSLPPQLLQYQCDQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDM 2490
LQ SLP L Q A T L Q F SP PM
Sbjct: 766 LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPF--SPSASLPMS- 822
Query: 2491 PYMIFDPNNPLMTGQLLGSSLTQMPPQASSSHT 2523
P P P +L + L Q+PP +S T
Sbjct: 823 PLATPPPQAP----PVLAAPLLQVPPSPPASPT 851
Score = 52.0 bits (123), Expect = 1e-05
Identities = 70/247 (28%), Positives = 93/247 (37%), Gaps = 55/247 (22%)
Query: 2325 TDAAKNAAAPAASSGSGTSTPLIPS----PKPE-------PEKTSP-KPEYPAEKPKQSD 2372
+ +A ++PA S S TP P+ PKP+ P+ T P K PA P S
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
Query: 2373 P--SPPSQGTK---------PALPLASTSSDPPQASTAQP--QPQPQPPKQPQLIGRPPS 2419
P +P GTK A PL +T P +T P P P P Q + PP+
Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 2420 ASQTPVPSS----------------PLQI--SMTSLQNSLPPQLLQYQCDQCTVAFPTLE 2461
+ P S P+Q+ S+TS PP L Q T + +
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Query: 2462 LWQEHQHMHFLAAQNQ-FLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPP-QAS 2519
L H + Q Q L SP RP P P++P + L SL PP Q S
Sbjct: 423 LQATHSFLTMSPRQTQASLTSP--SRPASTP-----PDSPPLQAPL---SLPASPPLQTS 472
Query: 2520 SSHTTAP 2526
S +P
Sbjct: 473 LSPAVSP 479
Score = 52.0 bits (123), Expect = 1e-05
Identities = 44/143 (30%), Positives = 53/143 (37%), Gaps = 23/143 (16%)
Query: 1952 PSSPETPPPPPPPPPLPPAP----PQPSSMGPVKIPNTVS-----TPLQAPPPTPPPP-- 2000
P SP PPP PP L P P P + P + P + S +PL PPP PP
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
Query: 2001 ----PPPPPPPPPP----PPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLAL 2052
PP PP P P PP P L L L P P P+ P L
Sbjct: 837 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG----PPPPPSRSPSSTL 892
Query: 2053 QLPQMDALSADLTQLCQQQLGLD 2075
P + S+ T ++ G D
Sbjct: 893 SGPDLAGHSSSATSTPEELRGYD 915
Score = 50.8 bits (120), Expect = 2e-05
Identities = 41/125 (32%), Positives = 50/125 (40%), Gaps = 22/125 (17%)
Query: 1949 PISPSSPETPPPPP-----PPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPP 2003
P +P+ P P P PP PP ++GP+ S+PL P P+ P
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS-----SSPLATPSPSGTKARPV 317
Query: 2004 PPPP------PPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLA---LQL 2054
PPP P PP PP A P P S P PS+ P PA PP A +
Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP--PSLQTLP-SPPATPPSQAPPSMTT 374
Query: 2055 PQMDA 2059
P M A
Sbjct: 375 PPMQA 379
Score = 50.4 bits (119), Expect = 3e-05
Identities = 41/121 (33%), Positives = 51/121 (42%), Gaps = 17/121 (14%)
Query: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMG--PVKIPNTVSTPLQAPPPTPPPPPPPPP-- 2005
++P + P P P A P PS PV P+ +TPL P PP PP P
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL--PATLPPSPPLATPLP 342
Query: 2006 --PPPPPPPP-----PPPSAPPQVQLPVSLDLPLF---PSIM-MQPVQHPALPPQLALQL 2054
PP P PP P P A P Q P S+ P PS+ + P+Q P +LQ
Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
Query: 2055 P 2055
P
Sbjct: 403 P 403
Score = 48.9 bits (115), Expect = 9e-05
Identities = 38/108 (35%), Positives = 48/108 (44%), Gaps = 14/108 (12%)
Query: 2343 STPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQG--TKPALPLASTSSDPPQA---S 2397
S PL P P P+ + + + P PSPP Q + PA P S S+ PP S
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698
Query: 2398 TAQP--QPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
A P Q P PP P P S S TP P +P ++ LQ +PP
Sbjct: 699 LAAPPLQVPPSPPASP-----PMSPSATPPPQAPPPLAAPPLQ--VPP 739
Score = 47.4 bits (111), Expect = 3e-04
Identities = 34/104 (32%), Positives = 39/104 (37%), Gaps = 1/104 (0%)
Query: 2344 TPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQP 2403
TP P+P P SP P E P PP A P PP + A P P
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619
Query: 2404 QPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQ 2447
Q P + PPS +P P SPL N+L LLQ
Sbjct: 620 QAPPXLALPPLQAPPSPPASP-PLSPLATPSPQAPNALAVHLLQ 662
Score = 45.4 bits (106), Expect = 0.001
Identities = 43/157 (27%), Positives = 59/157 (37%), Gaps = 38/157 (24%)
Query: 1952 PSSPETPPPPPPPPPLPP---APPQPSSMGPVKIPNTVSTP-LQAPPP------------ 1995
PS P TPP PP P APP ++ P+++P+++++P LQAPP
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
Query: 1996 -------------------TPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSI 2036
T P P PP PP AP + LP S L S
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP--LSLPASPPLQTSLSP 475
Query: 2037 MMQPVQHP-ALPPQLALQLPQMDALSADLTQLCQQQL 2072
+ P+ P + P AL + A L+ L L
Sbjct: 476 AVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
Score = 45.1 bits (105), Expect = 0.001
Identities = 42/125 (33%), Positives = 53/125 (42%), Gaps = 16/125 (12%)
Query: 2331 AAAPAASSGSGTSTPL--IPSPKPEPEKTSP--KPEYPAEKPKQSDPSPPSQGTKPALPL 2386
A P + + S PL +PSP P T P P A P Q+ PSPP+ + P PL
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA--SPPLSPL 645
Query: 2387 ASTSSDPPQAST-----AQPQPQPQPPKQPQL---IGRPPSASQTPVPSSPLQISMTSLQ 2438
A+ S P A A P P PP Q P S S TP +P ++ LQ
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Query: 2439 NSLPP 2443
+PP
Sbjct: 706 --VPP 708
Score = 44.3 bits (103), Expect = 0.002
Identities = 34/86 (39%), Positives = 40/86 (46%), Gaps = 15/86 (17%)
Query: 3050 PTAYPGLPGLPPVLL-PGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSA 3108
P A P P PPVL P + P S P P PP G P ++ S P L+L+ A
Sbjct: 823 PLATPP-PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG----PDTSVSGPRLTLALA 877
Query: 3109 PTKPLLQTPPPPPPPPPPPPSSSLSG 3134
P PPPPP PSS+LSG
Sbjct: 878 PG---------PPPPPSRSPSSTLSG 894
Score = 43.9 bits (102), Expect = 0.003
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 9/97 (9%)
Query: 3043 SLHGISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPA 3102
+L + P + P P L P+ P P++L + +PP + + P S +SP
Sbjct: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA-PFSPPPSPPVQAPFSPPASPP 684
Query: 3103 LSLSSAPTK--------PLLQTPPPPPPPPPPPPSSS 3131
+S S+ P P LQ PP PP PP PS++
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Score = 43.1 bits (100), Expect = 0.005
Identities = 29/82 (35%), Positives = 36/82 (43%), Gaps = 15/82 (18%)
Query: 3065 PGMNGPSSLPGFPQNSNTLTPPG-------AGMLGFPTSATSSPALSLSSAP-------- 3109
P + P S P P S + TPP A L P S +SP +S S+ P
Sbjct: 671 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 730
Query: 3110 TKPLLQTPPPPPPPPPPPPSSS 3131
P LQ PP PP PP PS++
Sbjct: 731 AAPPLQVPPSPPASPPMSPSAT 752
Score = 42.7 bits (99), Expect = 0.006
Identities = 29/86 (33%), Positives = 36/86 (41%), Gaps = 6/86 (6%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAG---MLGFPTSATSSPALSLS 3106
P+A P PP+ P + P S P P S + TPP + P SP SL
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL- 776
Query: 3107 SAPTKPLLQTPPPPPPPPPPPPSSSL 3132
P PL + PP PP PP +L
Sbjct: 777 --PMSPLAKPPPQAPPALATPPLQAL 800
Score = 42.0 bits (97), Expect = 0.011
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 11/108 (10%)
Query: 2343 STPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQ--GTKP-----ALPLASTSSDPPQ 2395
S P+ P KP P+ P A P Q+ PSPP+ G P +LP++ ++ PPQ
Sbjct: 775 SLPMSPLAKPPPQA----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830
Query: 2396 ASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
A P Q P P + + P P +S L +L P
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878
Score = 41.2 bits (95), Expect = 0.019
Identities = 38/117 (32%), Positives = 46/117 (39%), Gaps = 33/117 (28%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFP------QNSNTLTPPGAGML-----GFPTSAT 3098
P P L PP+ +P + P+SLP P Q L P L FP A
Sbjct: 754 PPRVPPLLAAPPLQVPP-SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP 812
Query: 3099 SSPALSLSSAP------------TKPLLQTPPPPPP---------PPPPPPSSSLSG 3134
SP+ SL +P PLLQ PP PP PP P P +S+SG
Sbjct: 813 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 869
Score = 39.7 bits (91), Expect = 0.054
Identities = 34/114 (29%), Positives = 44/114 (38%), Gaps = 14/114 (12%)
Query: 2334 PAASSGSGTSTPLIPSPKPEPEK-TSPKPEYP---AEKPKQSDPSPPSQGTKPALPLAST 2389
PA +PL P P +P P+ P A P Q PSP PL+
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP---------PLSPL 614
Query: 2390 SSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
++ PPQA P Q P P P S TP P +P +++ LQ P
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPP-ASPPLSPLATPSPQAPNALAVHLLQAPFSP 667
Score = 37.7 bits (86), Expect = 0.21
Identities = 38/151 (25%), Positives = 56/151 (37%), Gaps = 23/151 (15%)
Query: 1937 ARQYREAYDKLYPISPSSPETPPPPPPPP--------------PLPPAPPQPSSMGPVKI 1982
AR+ R A ++ P+ P PP P P P A +PS+ G ++
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 1983 P-----NTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSA----PPQVQLPVSLDLPLF 2033
P ++ +TPL +P + P P P P P P PPQV P P
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 2034 PSIMMQPVQHPALPPQLALQLPQMDALSADL 2064
+ P+ P+ A +P D + L
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPL 327
Score = 37.0 bits (84), Expect = 0.35
Identities = 26/102 (25%), Positives = 38/102 (37%), Gaps = 4/102 (3%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008
P + +P P P P P +P + P P + P P + P P P
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTP---PRKDAAPALGPLSSSPLATPSPSGTK 313
Query: 2009 PPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQL 2050
P PPP +A + + PL + + P P+ PP L
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAP-PSPSAPPSL 354
Score = 37.0 bits (84), Expect = 0.35
Identities = 35/114 (30%), Positives = 40/114 (35%), Gaps = 21/114 (18%)
Query: 3044 LHGISLPTAYPGLPGLP---PVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSS 3100
L S P P L P P L P + P S+ TPP P + S
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA----PPALASP 601
Query: 3101 PALSLSSAPTKPLLQTPPP-------------PPPPPPPPPSSSLSGQQTEQQN 3141
P L S P PL TPPP PP PP PP S L+ + N
Sbjct: 602 PLQGLPSPPLSPLA-TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654
Score = 36.2 bits (82), Expect = 0.60
Identities = 52/217 (23%), Positives = 78/217 (35%), Gaps = 23/217 (10%)
Query: 3056 LPGLPPVLLPGMNGPSSLPGFPQNSNTL-TPPGAGMLGFPTSATSSPALSLSSAPTKPLL 3114
LP PP+ P P S P P + TL +PP P S T+ P + S T P +
Sbjct: 331 LPPSPPLATPLPLAPPS-PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI 389
Query: 3115 QTP-----PPPPPPPPPPPSSSLS-----GQQTEQQN--------KESEKKQTKPNKVKK 3156
Q P P PP P SSL G T Q ++++ T P++
Sbjct: 390 QVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449
Query: 3157 IKEEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQLQALQNAIAGDPASFIGGQ 3216
+ P P +S + + + P LQAL + + P + +
Sbjct: 450 TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP--LQALSSLASHSPQAPLSSL 507
Query: 3217 FLPYFIPGFASYFTPQLPGTVQGGYFPPVCGMESLFP 3253
+P + +S P L PP+ + SL P
Sbjct: 508 IMPP-LETQSSLAPPSLQTPPASLTTPPLENLPSLAP 543
Score = 36.2 bits (82), Expect = 0.60
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 4/77 (5%)
Query: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAP 3109
P+A P P + P + P S P P S + TPP P + P S P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----PPPLAAPPLQVPPSPP 742
Query: 3110 TKPLLQTPPPPPPPPPP 3126
P + PPP PP
Sbjct: 743 ASPPMSPSATPPPRVPP 759
Score = 35.0 bits (79), Expect = 1.3
Identities = 31/89 (34%), Positives = 42/89 (47%), Gaps = 8/89 (8%)
Query: 3048 SLPTAYPGLPGLPPVLLPGMNGPSSL--PGFPQNSNTLTPPGAGMLGFPTSATSSPALSL 3105
SL + P P L +++P + SSL P +LT P L + + P L
Sbjct: 494 SLASHSPQAP-LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL----PSLAPPPLQT 548
Query: 3106 SSAP-TKPLLQTPPPPPPPPPPPPSSSLS 3133
+SAP T P L+TPP P P P P S L+
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLT 577
Score = 34.3 bits (77), Expect = 2.3
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 2/84 (2%)
Query: 3052 AYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTK 3111
A P L +PP+ +P SL P + LG PT + L++S T+
Sbjct: 379 APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438
Query: 3112 PLLQTP--PPPPPPPPPPPSSSLS 3133
L +P P PP PP + LS
Sbjct: 439 ASLTSPSRPASTPPDSPPLQAPLS 462
Score = 33.9 bits (76), Expect = 3.0
Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 3/71 (4%)
Query: 3061 PVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQT-PPP 3119
P+ P +G + P P N TP A + P AT P L+ S P LQT P P
Sbjct: 303 PLATPSPSGTKARP-VPPPDNAATPLPATLPPSPPLATPLP-LAPPSPSAPPSLQTLPSP 360
Query: 3120 PPPPPPPPPSS 3130
P PP P S
Sbjct: 361 PATPPSQAPPS 371
Score = 33.5 bits (75), Expect = 3.9
Identities = 29/111 (26%), Positives = 37/111 (33%), Gaps = 27/111 (24%)
Query: 3054 PGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLG-------------------FP 3094
P P P P + P SLP P +L+P + + P
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503
Query: 3095 TSATSSPALSLSSAPTKPLLQTPPPPPPPPP--------PPPSSSLSGQQT 3137
S+ P L S+ P LQTPP PP PPP + S T
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLT 554
Score = 33.1 bits (74), Expect = 5.1
Identities = 32/111 (28%), Positives = 44/111 (39%), Gaps = 14/111 (12%)
Query: 3031 LTVQQPGMMDSSSLHGISLPTAYPGLPGL-------PPVLLPGMNGPSSLPGFP-QNSNT 3082
LT+ + S + H P + +P L PP L P+SL P +N +
Sbjct: 484 LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL---QTPPASLTTPPLENLPS 540
Query: 3083 LTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLS 3133
L PP P + +P L P LQ PP P PPP SS++
Sbjct: 541 LAPPPLQTASAPLT---TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA 588
Score = 32.7 bits (73), Expect = 6.6
Identities = 32/106 (30%), Positives = 42/106 (39%), Gaps = 22/106 (20%)
Query: 2333 APAASSGSGTSTPLI-PSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGT-----KPALPL 2386
AP + S S +PL P P+ P +P + P PSPP+ T +P P
Sbjct: 811 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVP--------PSPPASPTLQAPRRPPTPG 862
Query: 2387 ASTSSDPPQASTAQ---PQPQPQPPKQ-----PQLIGRPPSASQTP 2424
TS P+ + A P P P P L G SA+ TP
Sbjct: 863 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 908
Score = 32.3 bits (72), Expect = 8.6
Identities = 38/136 (27%), Positives = 51/136 (37%), Gaps = 10/136 (7%)
Query: 3006 APTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLPGLPPVLLP 3065
+P T+ L A L + + L + P + SSL SL T L P LP
Sbjct: 482 SPLTIHPLQALSSLASHSPQAPLSSLIM--PPLETQSSLAPPSLQTPPASLTTPPLENLP 539
Query: 3066 GMNGP----SSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPP 3121
+ P +S P + T P L P S ++P S+ P Q PP
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
Query: 3122 PPP----PPPPSSSLS 3133
PP P PP S L+
Sbjct: 600 SPPLQGLPSPPLSPLA 615
Score = 32.3 bits (72), Expect = 8.6
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 2374 SPPSQGTKPALPLASTSSDPPQASTAQPQPQPQ----PPKQPQLIGRPPSASQTPVPSSP 2429
+PP+ T P L + + PP + + P P P P + PPS TP P +P
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584
Query: 2430 LQISMTSLQNSLPPQL 2445
I+ Q PP L
Sbjct: 585 SSIATPPPQ--APPAL 598
>gi|145309324 FH2 domain containing 1 [Homo sapiens]
Length = 1143
Score = 76.3 bits (186), Expect = 5e-13
Identities = 33/69 (47%), Positives = 38/69 (55%), Gaps = 11/69 (15%)
Query: 1956 ETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPP 2015
+TPPP PPPPP PP P P S + P+ +PPPPPPPP P PP PPPP
Sbjct: 28 QTPPPAPPPPPPPPPPSPPCSCSREECPS-----------SPPPPPPPPLPGEPPIPPPP 76
Query: 2016 PSAPPQVQL 2024
P PP +
Sbjct: 77 PGLPPTTHM 85
Score = 61.2 bits (147), Expect = 2e-08
Identities = 25/46 (54%), Positives = 27/46 (58%), Gaps = 11/46 (23%)
Query: 1991 QAPPPTPPPPPPPPPPPPP-----------PPPPPPPSAPPQVQLP 2025
Q PPP PPPPPPPPPP PP PPPPPPP P + +P
Sbjct: 28 QTPPPAPPPPPPPPPPSPPCSCSREECPSSPPPPPPPPLPGEPPIP 73
Score = 50.4 bits (119), Expect = 3e-05
Identities = 24/52 (46%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 2000 PPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQ---PVQHPALPP 2048
PPP PPPPPPPPPP PP + + + P S P P + + P P LPP
Sbjct: 30 PPPAPPPPPPPPPPSPPCSCSREECPSSPPPPPPPPLPGEPPIPPPPPGLPP 81
Score = 41.2 bits (95), Expect = 0.019
Identities = 19/37 (51%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
Query: 3104 SLSSAPTKPLLQTPPP--PPPPPPPPPSSSLSGQQTE 3138
++++AP + QTPPP PPPPPPPPPS S + E
Sbjct: 17 NIATAPGFMIGQTPPPAPPPPPPPPPPSPPCSCSREE 53
Score = 39.3 bits (90), Expect = 0.071
Identities = 19/36 (52%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 1952 PSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVS 1987
PSSP PPPPPP P PP PP P + P N S
Sbjct: 55 PSSPP-PPPPPPLPGEPPIPPPPPGLPPTTHMNGYS 89
Score = 35.8 bits (81), Expect = 0.78
Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 24/109 (22%)
Query: 3072 SLPGFPQNSNTLTPPGAGMLGF---------PTSATSSPALSLSSA---------PTKPL 3113
SL +N N T PG M+G P SP S S P PL
Sbjct: 8 SLVSDKENGNIATAPGF-MIGQTPPPAPPPPPPPPPPSPPCSCSREECPSSPPPPPPPPL 66
Query: 3114 LQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEEL 3162
PP PPPPP PP++ ++G + +KK+ + K I EE++
Sbjct: 67 PGEPPIPPPPPGLPPTTHMNG-----YSHLGKKKRMRSFFWKTIPEEQV 110
Score = 32.7 bits (73), Expect = 6.6
Identities = 42/153 (27%), Positives = 59/153 (38%), Gaps = 32/153 (20%)
Query: 2304 TEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTP------------------ 2345
+++ +TD V + +V + A+ P SSGS ++ P
Sbjct: 928 SQNPPSSTDTVWSRQNSVRRASTGAEEQRLPRGSSGSSSTRPGRDVPLQPRGSFKKPSAK 987
Query: 2346 ---LIPSPKPEPEKT----SPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQAST 2398
+P KPE KT S PE P E+PK PS PS LP + + AS+
Sbjct: 988 PLRNLPRQKPEENKTCRAHSEGPESPKEEPK--TPSVPS--VPHELPRVPSFARNTVASS 1043
Query: 2399 AQPQPQPQPP--KQPQLIGRPPSASQTPVPSSP 2429
++ PP K P I R S Q V P
Sbjct: 1044 SRSMRTDLPPVAKAPG-ITRTVSQRQLRVKGDP 1075
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 76.3 bits (186), Expect = 5e-13
Identities = 41/91 (45%), Positives = 41/91 (45%), Gaps = 28/91 (30%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP--- 2005
P P P PPPPPPPPP P P PPP PPPPPPPPP
Sbjct: 682 PPPPGFPPLPPPPPPPPPQPGFP--------------------MPPPLPPPPPPPPPAHP 721
Query: 2006 --PPPPPPPPPPPSAPPQVQLPVSLDLPLFP 2034
PPPP P PP PP LP LP FP
Sbjct: 722 AVTVPPPPLPAPPGVPPPPILP---PLPPFP 749
Score = 73.6 bits (179), Expect = 3e-12
Identities = 45/103 (43%), Positives = 53/103 (51%), Gaps = 8/103 (7%)
Query: 1952 PSSPETPPPPPPPPPLPP---APPQPSSMGP-VKIPNTVSTPLQAPPPTPPPPPP--PPP 2005
PS+P T P P + P A PS + P + +P P PPP PPPP P P P
Sbjct: 647 PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMP 706
Query: 2006 PPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048
PP PPPPPPPP A P V +P LP P + P+ P LPP
Sbjct: 707 PPLPPPPPPPPPAHPAVTVPPP-PLPAPPGVPPPPIL-PPLPP 747
Score = 70.9 bits (172), Expect = 2e-11
Identities = 38/81 (46%), Positives = 42/81 (51%), Gaps = 16/81 (19%)
Query: 1955 PETPPPPPP--------PPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
P PPPPPP PPPLPP PP P P V+ P PPP P PP PPPP
Sbjct: 689 PLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHP-----AVTVP---PPPLPAPPGVPPPP 740
Query: 2007 PPPPPPPPPPSAPPQVQLPVS 2027
PP PP PP P +Q+ +S
Sbjct: 741 ILPPLPPFPPGLFPVMQVDMS 761
Score = 53.9 bits (128), Expect = 3e-06
Identities = 27/59 (45%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 1967 LPPAPPQPSSMGPVKIPNTVSTPLQ-APPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQL 2024
L P PQ P TV+ + A P PPPP PP PPPPPPPPP P+ P +L
Sbjct: 1508 LLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKEL 1566
Score = 52.8 bits (125), Expect = 6e-06
Identities = 32/87 (36%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 1967 LPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPV 2026
+P AP + + + + AP P P PPPP PP PPPPP PPQ P+
Sbjct: 646 MPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPM 705
Query: 2027 SLDLPLFPSIMMQPVQHPAL---PPQL 2050
LP P P HPA+ PP L
Sbjct: 706 PPPLP--PPPPPPPPAHPAVTVPPPPL 730
Score = 48.9 bits (115), Expect = 9e-05
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 1960 PPPPPPPLPPAPPQPSSMGP-----VKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPP 2014
P PP + PP P V+ + PL PP PPP PP PP PPP P
Sbjct: 1241 PEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETT 1300
Query: 2015 PPSAPPQVQLPVSLDLP 2031
S P P++ D P
Sbjct: 1301 DASHPSVPPEPLAEDHP 1317
Score = 47.4 bits (111), Expect = 3e-04
Identities = 38/123 (30%), Positives = 46/123 (37%), Gaps = 31/123 (25%)
Query: 1932 ALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSM---GPVK------- 1981
AL R A L P+ P+ + PPP P P PS + GP+
Sbjct: 1442 ALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAA 1501
Query: 1982 -------IPNTVSTPLQAPPPTPPP------------PPPPPPPPPPPPPPPPPSAPPQV 2022
+P TP+ P T P P PPPP PP PPPPPPP
Sbjct: 1502 LGRELLLLPGQPQTPVF--PSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPT 1559
Query: 2023 QLP 2025
+LP
Sbjct: 1560 KLP 1562
Score = 42.4 bits (98), Expect = 0.008
Identities = 33/118 (27%), Positives = 41/118 (34%), Gaps = 28/118 (23%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPP- 2007
P+ P PP PPP PP PP+PP P T + PP P PP P
Sbjct: 1271 PMMLPLPLQPPLPPPRPPRPPSPPPE--------PETTDASHPSVPPEPLAEDHPPHTPG 1322
Query: 2008 --------------PPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLA 2051
P P PP + L +S P + P +PA P L+
Sbjct: 1323 LCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLS-----SPQVPGSPFSYPAPSPSLS 1375
Score = 42.4 bits (98), Expect = 0.008
Identities = 39/132 (29%), Positives = 53/132 (40%), Gaps = 13/132 (9%)
Query: 3054 PGLPGLPPVLLPGMNGPSSLP--GFPQNSNTLTPPGAGMLGFPTSATSSPALSLS----- 3106
PG P P + ++GP P G L PG S ++L
Sbjct: 1476 PGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAG 1535
Query: 3107 -SAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEELEAT 3165
AP PL PPPPPPPPP P + L ++ + Q SE P ++ EE +E
Sbjct: 1536 IPAPPPPLPPQPPPPPPPPPVEP-TKLPFKELDNQ-WPSEAIPPGPRGRDEVTEEYMELA 1593
Query: 3166 K---PEKHPKKE 3174
K P + P K+
Sbjct: 1594 KSRGPWRRPPKK 1605
Score = 42.0 bits (97), Expect = 0.011
Identities = 35/104 (33%), Positives = 39/104 (37%), Gaps = 25/104 (24%)
Query: 2331 AAAPAASSGSGTSTPLIPSP-----KPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALP 2385
AAA AA S + PL P P P P P+P +P P P PP PA P
Sbjct: 666 AAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPP----PPAHP 721
Query: 2386 LASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSP 2429
A T P P P PP G PP P+P P
Sbjct: 722 ----------AVTVPPPPLPAPP------GVPPPPILPPLPPFP 749
Score = 42.0 bits (97), Expect = 0.011
Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 6/80 (7%)
Query: 1947 LYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
L P P+ PP P P + P+ +P + PL P P PP PPP P
Sbjct: 1239 LSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPE 1298
Query: 2007 ------PPPPPPPPPPSAPP 2020
P PP P PP
Sbjct: 1299 TTDASHPSVPPEPLAEDHPP 1318
Score = 41.2 bits (95), Expect = 0.019
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 13/77 (16%)
Query: 3054 PGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPL 3113
PG P LPP P P PGFP PP P + PA+++ P
Sbjct: 685 PGFPPLPPPPPP----PPPQPGFPMPPPLPPPP-------PPPPPAHPAVTVPPPPLPAP 733
Query: 3114 LQTPPPP--PPPPPPPP 3128
PPPP PP PP PP
Sbjct: 734 PGVPPPPILPPLPPFPP 750
Score = 41.2 bits (95), Expect = 0.019
Identities = 31/85 (36%), Positives = 38/85 (44%), Gaps = 15/85 (17%)
Query: 1951 SPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPP---PPPP 2007
SP ET P P P PLP P+ +P + +AP P PP P P PPP
Sbjct: 1421 SPVLLETGLPLPLPLPLPL---------PLALPAVLRAQARAPTPLPPLLPAPLASCPPP 1471
Query: 2008 PPPPPPPPPSAPPQVQLPVSLDLPL 2032
P P +PP + +SLD PL
Sbjct: 1472 MKRKPGRPRRSPPSM---LSLDGPL 1493
Score = 40.8 bits (94), Expect = 0.024
Identities = 26/90 (28%), Positives = 29/90 (32%), Gaps = 21/90 (23%)
Query: 1948 YPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTP------------------ 1989
+ P T PPP PAP S+ P + P P
Sbjct: 368 FKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGE 427
Query: 1990 ---LQAPPPTPPPPPPPPPPPPPPPPPPPP 2016
APPP PP P P PP PPPP
Sbjct: 428 FRRAPAPPPLPPAEPLAKEKPGTPPGPPPP 457
Score = 40.0 bits (92), Expect = 0.041
Identities = 30/90 (33%), Positives = 35/90 (38%), Gaps = 18/90 (20%)
Query: 3039 MDSSSLHGISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSAT 3098
M S+ + P PG V P + P+ LP L PP GFP
Sbjct: 646 MPSAPITSADCPKPMVVTPGAAAVAAPSVLAPT-LP--------LPPPP----GFPPLPP 692
Query: 3099 SSPALSLSSAPTKPLLQTPPPPPPPPPPPP 3128
P P +P PPP PPPPPPPP
Sbjct: 693 PPPP-----PPPQPGFPMPPPLPPPPPPPP 717
Score = 37.7 bits (86), Expect = 0.21
Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 12/67 (17%)
Query: 1949 PISPSSPETPPP------------PPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPT 1996
P +P P T P P PPPPLPP PP P PV+ L P+
Sbjct: 1513 PQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPS 1572
Query: 1997 PPPPPPP 2003
PP P
Sbjct: 1573 EAIPPGP 1579
Score = 37.4 bits (85), Expect = 0.27
Identities = 63/278 (22%), Positives = 91/278 (32%), Gaps = 38/278 (13%)
Query: 3040 DSSSLHGISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATS 3099
DS++ P PG P + P P+ GA G A +
Sbjct: 374 DSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPA 433
Query: 3100 SPALSLSSAPTKPLLQTPPPPPPPPPPPPSSS--LSGQQTEQQNKESEKKQTKPNKVKKI 3157
P L P +PL + P PP PPPP ++S L G+ T + E P
Sbjct: 434 PPPLP----PAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPT----- 484
Query: 3158 KEEELEATKPEKHPKKEEKISSALSVLGKVVGETHV---DPIQLQALQNAIAGDPASFIG 3214
LE++ P K + + S + +L K + +P LQ + G P S
Sbjct: 485 ----LESS-PAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQ--MEGSPISSSS 537
Query: 3215 GQFLPYFIPGFASYFTPQLPGTVQGGYFPPVCGMESLFP---------------YGPTMP 3259
Q P + F + P G P G+E + P GP P
Sbjct: 538 SQLSP--LAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPP 595
Query: 3260 QTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQ 3297
P LL Q + +L ++ E QQ
Sbjct: 596 PEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQ 633
Score = 37.4 bits (85), Expect = 0.27
Identities = 32/123 (26%), Positives = 44/123 (35%), Gaps = 7/123 (5%)
Query: 1954 SPETPPPPPPPPPLPPAPPQPS-SMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPP 2012
+PE P PPLP +P+ S P + P P PP PP P
Sbjct: 1199 APEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER 1258
Query: 2013 PPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLCQQQL 2072
P + + P+ L LPL QP P PP+ P+ + A + + L
Sbjct: 1259 APEHDLEVEPEPPMMLPLPL------QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPL 1312
Query: 2073 GLD 2075
D
Sbjct: 1313 AED 1315
Score = 35.4 bits (80), Expect = 1.0
Identities = 35/150 (23%), Positives = 57/150 (38%), Gaps = 26/150 (17%)
Query: 2301 ESQTEDSMDATDQVVYKH-----CTVSGQTDAAKNAA----APAASSGSGTSTPLIPSPK 2351
ES+ D+ + + Y H V+G T A + ++ +G + P P+
Sbjct: 314 ESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQ 373
Query: 2352 --------PEPEKTSPKPEY-----PAEKPKQSDPSPPSQGTKPALPLASTSSDPPQAST 2398
P P + +P P + P + P P PP + T A A S + +A
Sbjct: 374 DSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRA-- 431
Query: 2399 AQPQPQPQPPKQPQLIGRPPSASQTPVPSS 2428
P P P PP +P +P + P P +
Sbjct: 432 --PAPPPLPPAEPLAKEKPGTPPGPPPPDT 459
Score = 35.4 bits (80), Expect = 1.0
Identities = 37/141 (26%), Positives = 45/141 (31%), Gaps = 41/141 (29%)
Query: 1960 PPPPPPPLPPAPP---------------------------QPSSMGPVKI-----PNTVS 1987
P PPP P PP P Q SS ++I P+
Sbjct: 592 PRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPI 651
Query: 1988 TPLQAPPP---TP------PPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMM 2038
T P P TP P P P PPPP PP PP P P+ P +
Sbjct: 652 TSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPP 711
Query: 2039 QPVQHPALPPQLALQLPQMDA 2059
P P P + + P + A
Sbjct: 712 PPPPPPPAHPAVTVPPPPLPA 732
Score = 35.4 bits (80), Expect = 1.0
Identities = 27/90 (30%), Positives = 33/90 (36%), Gaps = 9/90 (10%)
Query: 2343 STPLIPSPKPEPEKTSPKPEYPAEKPKQSD--PSPPSQGTKPALPLASTSSDPPQASTAQ 2400
S P+ + P+P +P A + P PP G P P PPQ
Sbjct: 648 SAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPP--PPPPPPPQPGFPM 705
Query: 2401 PQPQPQPPKQPQLIGRPPSASQTPVPSSPL 2430
P P P PP P PP+ VP PL
Sbjct: 706 PPPLPPPPPPP-----PPAHPAVTVPPPPL 730
Score = 34.3 bits (77), Expect = 2.3
Identities = 31/92 (33%), Positives = 35/92 (38%), Gaps = 16/92 (17%)
Query: 1949 PISPSSPETPPPPPPPPPLPPA--PPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP-- 2004
PIS SS + P P P P P S P ST L+ PTP P
Sbjct: 532 PISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPS------STGLEDISPTPLPDSDEDEE 585
Query: 2005 ------PPPPPPPPPPPPSAPPQVQLPVSLDL 2030
P PPP P PP P+ V+LDL
Sbjct: 586 LDLGLGPRPPPEPGPPDPAGLLSQTAEVALDL 617
Score = 34.3 bits (77), Expect = 2.3
Identities = 40/175 (22%), Positives = 69/175 (39%), Gaps = 26/175 (14%)
Query: 422 SVSLSHSSSESSKMSESKDQENNCE-------------RPKESNVLHPNGECPVKSEPTE 468
S S+ ES + + + CE RP L GE K +E
Sbjct: 984 STSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSE 1043
Query: 469 PGDEDEEDAYSNELDDEEVLGELTDSIGNKDFPLLNQSISPLSSSVLKFIEKGTSSSSAT 528
+ EE+ + E ++EE + D ++D + + LS + K ++G S T
Sbjct: 1044 EQESTEEEEEAEEEEEEE--DDDDDDSDDRDESENDDEDTALSEASEK--DEGDSDEEET 1099
Query: 529 VSDDTEKKKQTAAVRASGSVASNYGISGKDFADASASKDSATAAHPSEIARGDED 583
VS T K + T++ +S S +F +S S S++ +AR +E+
Sbjct: 1100 VSIVTSKAEATSSSESSES---------SEFESSSESSPSSSEDEEEVVAREEEE 1145
Score = 33.5 bits (75), Expect = 3.9
Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 13/97 (13%)
Query: 2345 PLIPSPKPEPEKT-SPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQ- 2402
P PSP PEPE T + P P E P D P + G +L + ++ P +P
Sbjct: 1288 PRPPSPPPEPETTDASHPSVPPE-PLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPL 1346
Query: 2403 ---------PQPQPPKQPQLIGRP-PSASQTPVPSSP 2429
PQ P P P PS S +P +P
Sbjct: 1347 SGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTP 1383
Score = 33.5 bits (75), Expect = 3.9
Identities = 25/78 (32%), Positives = 30/78 (38%), Gaps = 16/78 (20%)
Query: 1962 PPPPPLPPAPPQPSSM-----GPVKIPNTVSTPLQAPPPTPPPPP-----------PPPP 2005
P P L P P P+ GP+ P + T L P P P P P P
Sbjct: 1396 PSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPT 1455
Query: 2006 PPPPPPPPPPPSAPPQVQ 2023
P PP P P S PP ++
Sbjct: 1456 PLPPLLPAPLASCPPPMK 1473
Score = 33.1 bits (74), Expect = 5.1
Identities = 41/175 (23%), Positives = 68/175 (38%), Gaps = 24/175 (13%)
Query: 2292 KDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPK 2351
++E+++ ++E E+SM + ++ G+ +AA APA S I +
Sbjct: 1142 EEEEEEEEEEMVAEESMASAGPEDFEQ---DGE-EAALAPGAPAVDSLGMEEEVDIETEA 1197
Query: 2352 PEPEKTSPKPEYP-----AEKPKQSDPSPPSQG--------TKPALPLASTSSDPPQAST 2398
PE+ + P E+P S P G P P + PP +
Sbjct: 1198 VAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPE 1257
Query: 2399 AQP----QPQPQPPKQPQLIGRPPSASQTP--VPSSPLQISMTSLQN-SLPPQLL 2446
P + +P+PP L +PP P PS P + T + S+PP+ L
Sbjct: 1258 RAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPL 1312
Score = 33.1 bits (74), Expect = 5.1
Identities = 31/96 (32%), Positives = 37/96 (38%), Gaps = 20/96 (20%)
Query: 2347 IPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQ-----ASTAQP 2401
+P P P P+P P +P+ +D S PS P PLA PP S A+
Sbjct: 1276 LPLQPPLPPPRPPRPPSPPPEPETTDASHPS---VPPEPLA--EDHPPHTPGLCGSLAKS 1330
Query: 2402 QPQPQPPKQPQLIGRPP--------SASQTPVPSSP 2429
Q P P G PP S S VP SP
Sbjct: 1331 QSTETVPATPG--GEPPLSGGSSGLSLSSPQVPGSP 1364
Score = 32.3 bits (72), Expect = 8.6
Identities = 34/128 (26%), Positives = 46/128 (35%), Gaps = 37/128 (28%)
Query: 2345 PLIPSPK---PEPEKTSPKPEYPAEKPKQSDPS----------PPSQGT--KPALPLAST 2389
PL+P+P P P K P +P++S PS PP+ + L L
Sbjct: 1459 PLLPAPLASCPPPMKRKPG------RPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQ 1512
Query: 2390 SSDPPQASTAQPQ-----------PQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQ 2438
P ST P+ P P PP PQ PP P P P ++ L
Sbjct: 1513 PQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPP-----PPPVEPTKLPFKELD 1567
Query: 2439 NSLPPQLL 2446
N P + +
Sbjct: 1568 NQWPSEAI 1575
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 75.5 bits (184), Expect = 9e-13
Identities = 42/112 (37%), Positives = 49/112 (43%), Gaps = 22/112 (19%)
Query: 1937 ARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPT 1996
A + A +K P P TPP P PPPPLPP P PPP
Sbjct: 387 AEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSP------------------PPPL 428
Query: 1997 PPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048
PPPPPP PPP P PPPPP+ Q + P P+ P+ + P L P
Sbjct: 429 CPPPPPPVSPPPLPSPPPPPAQEEQEESPP----PVVPATCSRKRGRPPLTP 476
Score = 67.0 bits (162), Expect = 3e-10
Identities = 45/137 (32%), Positives = 54/137 (39%), Gaps = 29/137 (21%)
Query: 1956 ETPPPPPPP-------PPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPP--------- 1999
E PP PP PP+ +PP P PV P TP P P P
Sbjct: 549 EDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPT 608
Query: 2000 ----------PPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLF-PSIMMQPVQHPAL-- 2046
PPPPP PPPPP P PPP+ + P+ L P F PS + L
Sbjct: 609 FRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTP 668
Query: 2047 PPQLALQLPQMDALSAD 2063
PP A + P+ + AD
Sbjct: 669 PPLGAPEAPEPEPPPAD 685
Score = 65.1 bits (157), Expect = 1e-09
Identities = 48/137 (35%), Positives = 55/137 (40%), Gaps = 22/137 (16%)
Query: 1955 PETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQA----------PPPTPPPPPPPP 2004
P P PPPPP P PP P SS P+ + TP +A PPP P P P
Sbjct: 620 PPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEP 679
Query: 2005 PPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALP---------PQLALQLP 2055
PPP P P P V L LP F ++ PV+ P PQ QL
Sbjct: 680 EPPPADDSPAEPE-PRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQL- 737
Query: 2056 QMDALSADLTQLCQQQL 2072
+ L A TQL Q L
Sbjct: 738 -LQPLQALQTQLLPQAL 753
Score = 62.4 bits (150), Expect = 8e-09
Identities = 36/100 (36%), Positives = 45/100 (45%), Gaps = 10/100 (10%)
Query: 1951 SPSSPETPPPPPPPP--PLPPAPPQP---SSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP 2005
SP P+ P P P PP P PP+ P P ++ P T L P PPP PPPPP
Sbjct: 570 SPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPP 629
Query: 2006 PPPPPPPPPPPSAPPQVQ-----LPVSLDLPLFPSIMMQP 2040
P PPP P S P + P L ++ S++ P
Sbjct: 630 APSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPP 669
Score = 52.4 bits (124), Expect = 8e-06
Identities = 33/94 (35%), Positives = 37/94 (39%), Gaps = 23/94 (24%)
Query: 1951 SPSSPETPPPPPP--PPPLPPAPPQPSS-----MGPVKIPNTVSTPLQAPPPTPP----- 1998
SP P PPPPPP PPPLP PP P+ P +P T S PP TP
Sbjct: 423 SPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAER 482
Query: 1999 -----------PPPPPPPPPPPPPPPPPPSAPPQ 2021
PP P P PP P+ P+
Sbjct: 483 EAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPK 516
Score = 48.9 bits (115), Expect = 9e-05
Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 7/79 (8%)
Query: 1998 PPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQM 2057
PPPP PP P PPPP PPPS P P L P P + P+ P PP Q Q
Sbjct: 402 PPPPLTPPAPSPPPPLPPPSTSP----PPPLCPPPPPPVSPPPLPSPPPPP---AQEEQE 454
Query: 2058 DALSADLTQLCQQQLGLDP 2076
++ + C ++ G P
Sbjct: 455 ESPPPVVPATCSRKRGRPP 473
Score = 47.8 bits (112), Expect = 2e-04
Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 9/122 (7%)
Query: 1942 EAYDKLY-----PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPT 1996
EA+ K+Y P +PE P P PPP PA P+P ++G N +S P AP T
Sbjct: 656 EAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRT---NHLSLPRFAPVVT 712
Query: 1997 PPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQ 2056
P P P P + +Q +L L P + P Q PP Q+P
Sbjct: 713 TPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQ-ALPPPQPQLQPPPSPQQMPP 771
Query: 2057 MD 2058
++
Sbjct: 772 LE 773
Score = 46.2 bits (108), Expect = 6e-04
Identities = 35/143 (24%), Positives = 51/143 (35%), Gaps = 4/143 (2%)
Query: 2290 CYKDED---DDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPL 2346
C+K ++ DD ++E + E+ D + + AA+ A P
Sbjct: 353 CWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS 412
Query: 2347 IPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQ 2406
P P P P + P P P P S P PS PA S PP + + +
Sbjct: 413 PPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE-EQEESPPPVVPATCSRKRGR 471
Query: 2407 PPKQPQLIGRPPSASQTPVPSSP 2429
PP P +A P +SP
Sbjct: 472 PPLTPSQRAEREAARAGPEGTSP 494
Score = 42.7 bits (99), Expect = 0.006
Identities = 34/161 (21%), Positives = 58/161 (36%), Gaps = 18/161 (11%)
Query: 2286 QKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTP 2345
Q+++ +E++ ++E + ++ + ++ V + + + + AK P P
Sbjct: 357 QEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPP 416
Query: 2346 LIPSPKPEPEKTSPKPEYPAEKPKQSDPSPP------SQGTKPALPLAST--SSDPP--- 2394
L P P P P P P P PP + P +P + PP
Sbjct: 417 LPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTP 476
Query: 2395 ------QASTAQPQ-PQPQPPKQPQLIGRPPSASQTPVPSS 2428
+A+ A P+ P P G PP S T P S
Sbjct: 477 SQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKS 517
Score = 42.4 bits (98), Expect = 0.008
Identities = 32/89 (35%), Positives = 34/89 (38%), Gaps = 16/89 (17%)
Query: 1949 PISPSS----------PETPPPPPP---PPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPP 1995
P SPSS P+ P PP P PL P PP P P S L+ PPP
Sbjct: 1888 PGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASP---PLKTSPQLRVPPP 1944
Query: 1996 TPPPPPPPPPPPPPPPPPPPPSAPPQVQL 2024
T P PP P PS PP L
Sbjct: 1945 TSVVTALTPTSGELAPPGPAPSPPPPEDL 1973
Score = 40.4 bits (93), Expect = 0.032
Identities = 28/86 (32%), Positives = 30/86 (34%), Gaps = 16/86 (18%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTP----------- 1997
P P SP P PPP PPA + P +P T S PP TP
Sbjct: 432 PPPPVSPPPLPSPPP----PPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARA 487
Query: 1998 -PPPPPPPPPPPPPPPPPPPSAPPQV 2022
P PP P P PP P V
Sbjct: 488 GPEGTSPPTPTPSTATGGPPEDSPTV 513
Score = 40.4 bits (93), Expect = 0.032
Identities = 39/141 (27%), Positives = 50/141 (35%), Gaps = 26/141 (18%)
Query: 1949 PISPSSPETPPPPPPP--------PPLPPA--PPQPSSMGPVKIPNTVST-----PLQAP 1993
P+ P S PPP P P P+ P S GP+ P + S+ P
Sbjct: 1844 PLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGD 1903
Query: 1994 PPTPPPPPPPPPPPP--PPPPP-----PPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPAL 2046
P P PP P P P PPP PP PQ+++P P + P
Sbjct: 1904 PDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPP----PTSVVTALTPTSGELA 1959
Query: 2047 PPQLALQLPQMDALSADLTQL 2067
PP A P + L D +
Sbjct: 1960 PPGPAPSPPPPEDLGPDFEDM 1980
Score = 38.9 bits (89), Expect = 0.092
Identities = 79/326 (24%), Positives = 117/326 (35%), Gaps = 64/326 (19%)
Query: 3061 PVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPAL-----SLSSAPT---KP 3112
PVL P + +P P + +PP A PT ++ L S+ PT
Sbjct: 561 PVLRPPITTSPPVPQEP--APVPSPPRA-----PTPPSTPVPLPEKRRSILREPTFRWTS 613
Query: 3113 LLQTPPPPPPPPPPPPSSSLSGQQTEQQNKE--SEKKQTKPNKVK-KIKEEEL------- 3162
L + PPPPP PPPPP+ S + Q P++ KI E L
Sbjct: 614 LTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGA 673
Query: 3163 -EATKPEKHPKKEEKISSALSVLGK--------------VVGETHVDPIQLQALQN---- 3203
EA +PE P + +G+ + V P AL N
Sbjct: 674 PEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQT 733
Query: 3204 -AIAGDPASFIGGQFLPYFIPGFASYFTPQLPGTVQGGYFPP-----VCGMESLFPYGPT 3257
A P + Q LP +P PQL PP + G+ SL G
Sbjct: 734 QAQLLQPLQALQTQLLPQALPP----PQPQLQPPPSPQQMPPLEKARIAGVGSLPLSG-- 787
Query: 3258 MPQTLAGLSPGALLQQY---QQYQQNLQESLQKQQKQQQEQQQKPVQAKTSKVESDQPQN 3314
+ + + L A +Q + QQ QQ + S+ Q E+ V ++ P
Sbjct: 788 VEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEE----VAGAVKQISDRGPVR 843
Query: 3315 SNDAS-ETKEDKSTATESTKEEPQLE 3339
S D S E K ++ + ES + P+++
Sbjct: 844 SEDESVEAKRERPSGPESPVQGPRIK 869
Score = 38.1 bits (87), Expect = 0.16
Identities = 36/135 (26%), Positives = 45/135 (33%), Gaps = 33/135 (24%)
Query: 1952 PSSPETPPPPP------PPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPP--- 2002
P PP PP P L +P P+ +P + + P P PP P
Sbjct: 2131 PREESLPPAPPLANGSQPSQGLTASPADPTRTF-AWLPGAPGVRVLSLGPAPEPPKPATS 2189
Query: 2003 --------------------PPPPP---PPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQ 2039
P PPP PP PP P+AP LP L + P + +
Sbjct: 2190 KIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVV 2249
Query: 2040 PVQHPALPPQLALQL 2054
P PP L L L
Sbjct: 2250 RPAPPPPPPPLTLVL 2264
Score = 38.1 bits (87), Expect = 0.16
Identities = 29/108 (26%), Positives = 41/108 (37%), Gaps = 6/108 (5%)
Query: 1959 PPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPP-----PPP 2013
P P PP P + +G V + PPP PP PP P P PP
Sbjct: 2179 PAPEPPKPATSKIILVNKLGQVFV-KMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPG 2237
Query: 2014 PPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALS 2061
P P V + P P + + PA PP+ A+++ ++ S
Sbjct: 2238 PLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFS 2285
Score = 37.7 bits (86), Expect = 0.21
Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 12/104 (11%)
Query: 3073 LPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSL 3132
+P + L PP P + + P L S P L PPPPP PPP PS
Sbjct: 391 MPAAEKEEAKLPPPPLT----PPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPP 446
Query: 3133 SGQQTEQQNKE--------SEKKQTKPNKVKKIKEEELEATKPE 3168
Q EQ+ S K+ P + E E PE
Sbjct: 447 PPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE 490
Score = 37.7 bits (86), Expect = 0.21
Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 54/157 (34%)
Query: 2328 AKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPK------------------ 2369
++ A AA +G ++P P+P P P + P PK
Sbjct: 477 SQRAEREAARAGPEGTSP--PTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSA 534
Query: 2370 --------------QSDPSPPSQGTKPAL-PLASTSSDPPQASTAQPQPQPQPPKQPQLI 2414
+ P PP P L P +TS PQ +P P P PP+ P
Sbjct: 535 RSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQ----EPAPVPSPPRAP--- 587
Query: 2415 GRPPSASQTPVPSSPLQISM--------TSLQNSLPP 2443
PPS TPVP + S+ TSL LPP
Sbjct: 588 -TPPS---TPVPLPEKRRSILREPTFRWTSLTRELPP 620
Score = 37.7 bits (86), Expect = 0.21
Identities = 30/105 (28%), Positives = 38/105 (36%), Gaps = 29/105 (27%)
Query: 1953 SSPETPPPPP----PPPPLPPAPPQPSS--------MGPV---KIPNTVSTPLQAPPPTP 1997
+SP TP P PP P P+ ++ + PV + + TP + P
Sbjct: 492 TSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDP 551
Query: 1998 PPPPP--------------PPPPPPPPPPPPPPSAPPQVQLPVSL 2028
P PP PP P P P P PP AP PV L
Sbjct: 552 PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL 596
Score = 37.4 bits (85), Expect = 0.27
Identities = 31/100 (31%), Positives = 35/100 (35%), Gaps = 40/100 (40%)
Query: 1949 PISP--SSPETPPPPPPPPP----LPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPP 2002
P+ P P PP P P LPP P +G + + V P PPPPPP
Sbjct: 2210 PVPPPVKQPPLPPTISPTAPTSWTLPPGP----LLGVLPVVGVVR-------PAPPPPPP 2258
Query: 2003 P--------PPPPP---------------PPPPPPPPSAP 2019
P P PP PP PPP AP
Sbjct: 2259 PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAP 2298
Score = 35.4 bits (80), Expect = 1.0
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 3/94 (3%)
Query: 2351 KPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQ-PPK 2409
K E E+ + E E+ + P ++ + LP + PP S P P P P
Sbjct: 368 KKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLT--PPAPSPPPPLPPPSTSPP 425
Query: 2410 QPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
P PP S P+PS P + + S PP
Sbjct: 426 PPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPP 459
Score = 35.4 bits (80), Expect = 1.0
Identities = 24/86 (27%), Positives = 32/86 (37%), Gaps = 7/86 (8%)
Query: 2345 PLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALP------LASTSSDPPQAST 2398
P+ SP P P++ +P P P S P P + + L + T PP
Sbjct: 566 PITTSP-PVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
Query: 2399 AQPQPQPQPPKQPQLIGRPPSASQTP 2424
P P P PP P R P + P
Sbjct: 625 PPPPPAPSPPPAPATSSRRPLLLRAP 650
Score = 34.7 bits (78), Expect = 1.7
Identities = 89/387 (22%), Positives = 128/387 (33%), Gaps = 79/387 (20%)
Query: 3005 LAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISLPTAYPGLP------- 3057
LAP+ ++LD + +D VQQP G P + PG+
Sbjct: 2047 LAPSATPGAPRIEQLDGVDDGTDSEAEAVQQP--------RGQGTPPSGPGVVRAGVLGA 2098
Query: 3058 ----GLPPVLLPG---------MNGPS---------SLPGFPQNSNTLTPPGAGMLGFPT 3095
PP LP + GP SLP P +N + P G+ P
Sbjct: 2099 AGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANG-SQPSQGLTASPA 2157
Query: 3096 SATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVK 3155
T + A L AP +L P P PP P L + + K + + + P VK
Sbjct: 2158 DPTRTFAW-LPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVK 2216
Query: 3156 KIK-EEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQLQ-ALQNAIAGDPASFI 3213
+ + T P + L V+G V P L L + A P I
Sbjct: 2217 QPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAI 2276
Query: 3214 GGQFL------------PYFIP-----GFASYFTPQLPGTVQGGY------FPPVCGMES 3250
+ + PY P G AS TPQ+PG GG+ P V G+
Sbjct: 2277 RVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLD 2336
Query: 3251 LFPYGPTMPQTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQKPVQAKTSKVESD 3310
L G + SPG LQE + Q P +ES
Sbjct: 2337 LDRPGEPAGEE----SPGP-----------LQERSPLLPLPEDGPPQVPDGPPDLLLESQ 2381
Query: 3311 QPQNSNDASETKEDKSTATESTKEEPQ 3337
S +AS ++E+ + + + P+
Sbjct: 2382 WHHYSGEASSSEEEPPSPDDKENQAPK 2408
Score = 34.3 bits (77), Expect = 2.3
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 36/126 (28%)
Query: 2346 LIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPAL------PLASTS--------- 2390
L P P PE +P+PE P ++P P + G L P+ +T
Sbjct: 666 LTPPPLGAPE--APEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG 723
Query: 2391 --------------SDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTS 2436
P QA Q PQ PP QPQL PPS Q P PL+ + +
Sbjct: 724 APALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQL-QPPPSPQQMP----PLEKARIA 778
Query: 2437 LQNSLP 2442
SLP
Sbjct: 779 GVGSLP 784
Score = 33.1 bits (74), Expect = 5.1
Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 10/90 (11%)
Query: 2334 PAASSGSGTST----PLIPSPK-PEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPL-- 2386
P S GS +S P + P P P + S +P A +P S + P T P L +
Sbjct: 1884 PLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPP 1943
Query: 2387 ---ASTSSDPPQASTAQPQPQPQPPKQPQL 2413
T+ P A P P P PP L
Sbjct: 1944 PTSVVTALTPTSGELAPPGPAPSPPPPEDL 1973
Score = 32.3 bits (72), Expect = 8.6
Identities = 31/143 (21%), Positives = 50/143 (34%), Gaps = 40/143 (27%)
Query: 2333 APAASSGSGTSTPLIPSPKPEPEKTSPK--------------PEYPAEKPKQSDPSPPSQ 2378
AP S + P P P PE ++ + P PA P + PP+
Sbjct: 578 APVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAP 637
Query: 2379 GTKPALPLA-----------------STSSDPPQASTAQPQPQPQP------PKQPQLIG 2415
T PL S + PP + P+P+P P +P+ +G
Sbjct: 638 ATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVG 697
Query: 2416 RPPSASQ---TPVPSSPLQISMT 2435
R S PV ++P++ ++
Sbjct: 698 RTNHLSLPRFAPVVTTPVKAEVS 720
>gi|115511042 zinc finger protein 493 isoform 1 [Homo sapiens]
Length = 646
Score = 74.7 bits (182), Expect = 2e-12
Identities = 70/267 (26%), Positives = 112/267 (41%), Gaps = 33/267 (12%)
Query: 1352 YRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAEL 1411
+RC C A+K L H + H C C ++F F L KH + H E +
Sbjct: 277 HRCEECGKAYKESSHLTTHKRIHTGEKPYKCEECGKTFSVFSILTKH-KIIHTEEKPYKC 335
Query: 1412 QQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPD-DMGS 1470
++ G+ + S T+++ H + E+ Y+ + GKA S S G
Sbjct: 336 EEC-------GKAFKRSSTLTK--HRIIHTEEKPYKCEECGKAFNQSSTLSIHKIIHTGE 386
Query: 1471 EPKRT----LPFRKGPNFTMEKFLDPS-RPYKCTVCKESFTQKNILLVHYNSVSHLHKLK 1525
+P + F++ T+ K + +PYKC C ++F + + L H + HK
Sbjct: 387 KPYKCEECGKAFKRSSTLTIHKMIHTGEKPYKCEECGKAFNRSSHLTTH-KRIHTGHKPY 445
Query: 1526 KVLQ-----EASSPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAK 1580
K + S + + +TD KPYKC C A+++SS L IH + +H T + K
Sbjct: 446 KCKECGKSFSVFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILSIHKK--IH-TGEKPYK 502
Query: 1581 LEPSG-------HVAGGHSIAANVNSP 1600
E G H+A GH +V P
Sbjct: 503 CEECGKAFKRSSHLA-GHKQIHSVQKP 528
Score = 57.8 bits (138), Expect = 2e-07
Identities = 59/246 (23%), Positives = 93/246 (37%), Gaps = 27/246 (10%)
Query: 1352 YRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAEL 1411
Y+C F L H H C C ++F F KH + H E
Sbjct: 165 YKCEQYGKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKH-KIIHTEEKSHRC 223
Query: 1412 QQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMGSE 1471
++ A E+ H E+ Y+ + GKA + S + E
Sbjct: 224 EEYCK---------AYKESSHLTTHKRIHTGEKPYKCEECGKAFSIFSTLTKHKIIHTEE 274
Query: 1472 PKRTLP-----FRKGPNFTMEKFLDPS-RPYKCTVCKESFTQKNILLVHYNSVSHLHKLK 1525
+++ + T K + +PYKC C ++F+ +IL H + H +
Sbjct: 275 KSHRCEECGKAYKESSHLTTHKRIHTGEKPYKCEECGKTFSVFSILTKH--KIIHTEEKP 332
Query: 1526 KVLQEA------SSPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAA 1579
+E SS + + +T+ KPYKC C A++QSSTL IH ++H T +
Sbjct: 333 YKCEECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFNQSSTLSIH--KIIH-TGEKPY 389
Query: 1580 KLEPSG 1585
K E G
Sbjct: 390 KCEECG 395
Score = 56.2 bits (134), Expect = 6e-07
Identities = 61/250 (24%), Positives = 96/250 (38%), Gaps = 35/250 (14%)
Query: 1352 YRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKH--LEAGHPELSEA 1409
Y+C C AFK L H H C C ++F L H + G
Sbjct: 333 YKCEECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFNQSSTLSIHKIIHTGEKPYKCE 392
Query: 1410 ELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPD-DM 1468
E G+ + S T++ H + E+ Y+ + GKA S ++
Sbjct: 393 EC----------GKAFKRSSTLTI--HKMIHTGEKPYKCEECGKAFNRSSHLTTHKRIHT 440
Query: 1469 GSEPKRTLPFRKG----PNFTMEKFLDPSR-PYKCTVCKESFTQKNILLVHYNSVSHLHK 1523
G +P + K T K + + PYKC C ++F + +IL +H +H
Sbjct: 441 GHKPYKCKECGKSFSVFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILSIH----KKIHT 496
Query: 1524 LKKVLQ--------EASSPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTK 1575
+K + + SS + ++ KPYKC C A+S STL H ++H T+
Sbjct: 497 GEKPYKCEECGKAFKRSSHLAGHKQIHSVQKPYKCEECGKAFSIFSTLTKH--KIIH-TE 553
Query: 1576 ARAAKLEPSG 1585
+ K E G
Sbjct: 554 EKPYKCEKCG 563
Score = 55.5 bits (132), Expect = 1e-06
Identities = 59/240 (24%), Positives = 94/240 (39%), Gaps = 43/240 (17%)
Query: 1352 YRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKH--LEAGHPELSEA 1409
Y+C C AFK L IH H C C ++F L H + GH
Sbjct: 389 YKCEECGKAFKRSSTLTIHKMIHTGEKPYKCEECGKAFNRSSHLTTHKRIHTGHKPYKCK 448
Query: 1410 ELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMG 1469
E G+ ++ T+++ H + ++ Y+ + GKA + SSI
Sbjct: 449 EC----------GKSFSVFSTLTK--HKIIHTDKKPYKCEECGKAF----NRSSI----- 487
Query: 1470 SEPKRTLPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVH--YNSVSHLHKLKKV 1527
L K K +PYKC C ++F + + L H +SV +K ++
Sbjct: 488 ------LSIHK-------KIHTGEKPYKCEECGKAFKRSSHLAGHKQIHSVQKPYKCEEC 534
Query: 1528 LQEAS--SPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSG 1585
+ S S + + +T+ KPYKC C + + S L H ++H T + K E G
Sbjct: 535 GKAFSIFSTLTKHKIIHTEEKPYKCEKCGKTFYRFSNLNTH--KIIH-TGEKPCKCEECG 591
Score = 54.7 bits (130), Expect = 2e-06
Identities = 55/228 (24%), Positives = 86/228 (37%), Gaps = 26/228 (11%)
Query: 1352 YRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAEL 1411
Y+C C AF L H + H C C +SF F L KH + H + +
Sbjct: 417 YKCEECGKAFNRSSHLTTHKRIHTGHKPYKCKECGKSFSVFSTLTKH-KIIHTDKKPYKC 475
Query: 1412 QQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMGSE 1471
++ G+ + S +S H E+ Y+ + GKA S + + S
Sbjct: 476 EEC-------GKAFNRSSILSI--HKKIHTGEKPYKCEECGKAFKRSSHLAG-HKQIHSV 525
Query: 1472 PKRTLPFRKGPNFTMEKFLDP-------SRPYKCTVCKESFTQKNILLVHYNSVSHLHKL 1524
K G F++ L +PYKC C ++F + + L H + H +
Sbjct: 526 QKPYKCEECGKAFSIFSTLTKHKIIHTEEKPYKCEKCGKTFYRFSNLNTH--KIIHTGEK 583
Query: 1525 KKVLQEASSPVPQETNS------NTDNKPYKCSICNVAYSQSSTLEIH 1566
+E +N +T +KPYKC C A+ +SS L H
Sbjct: 584 PCKCEECGKAFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRH 631
Score = 40.8 bits (94), Expect = 0.024
Identities = 31/116 (26%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 614 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 673
+C + S +L GH + N K KC +C + T H E
Sbjct: 166 KCEQYGKTFNQSSTLTGHKII---HNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKSHR 222
Query: 674 CV-YCKTGQPHPRLARGESYTCGYKPFRCEVCN-----YSTTTKGNLSIHMQSDKH 723
C YCK + L + G KP++CE C +ST TK + IH + H
Sbjct: 223 CEEYCKAYKESSHLTTHKRIHTGEKPYKCEECGKAFSIFSTLTKHKI-IHTEEKSH 277
Score = 38.5 bits (88), Expect = 0.12
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 1478 FRKGPNFTMEKFLDPS-RPYKCTVCKESFTQKNIL----LVHYNSVSH-LHKLKKVLQEA 1531
F + N T K + +PYKC C SF Q + L L+H + + K ++
Sbjct: 118 FNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQS 177
Query: 1532 SSPVPQETNSNTDNKPYKCSICNVAYSQSSTLE----IHMRSVLHQTKARAAKLEPSGHV 1587
S+ + N + KPYKC C A+S ST IH H+ + + S H+
Sbjct: 178 STLTGHKIIHNGE-KPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEEYCKAYKESSHL 236
Score = 37.7 bits (86), Expect = 0.21
Identities = 39/173 (22%), Positives = 63/173 (36%), Gaps = 16/173 (9%)
Query: 614 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 673
+C +C S +L H ++H+ K KC +C + TL H E
Sbjct: 334 KCEECGKAFKRSSTLTKHR-IIHTEE--KPYKCEECGKAFNQSSTLSIHKIIHTGEKPYK 390
Query: 674 CVYC-KTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQN 732
C C K + L + G KP++CE C + N S H+ + K ++
Sbjct: 391 CEECGKAFKRSSTLTIHKMIHTGEKPYKCEECGKAF----NRSSHLTTHKRIH------- 439
Query: 733 GNGEQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVARNLRIH 785
G + + + S+ T K ++CE C N + L IH
Sbjct: 440 -TGHKPYKCKECGKSFSVFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILSIH 491
Score = 36.6 bits (83), Expect = 0.46
Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 14/115 (12%)
Query: 1496 YKCTVCKESFTQKNILL----VHYNSVSHLHKLKKVLQEASSPVPQETNSNTDNKPYKCS 1551
Y+C C ++F + L VH S+ ++ K + S+ + +T KPYKC
Sbjct: 82 YRCEECGKAFIWFSTLTRHRRVHTGEKSYKYECGKSFNQDSN-LTTHKRIHTGQKPYKCE 140
Query: 1552 ICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAG------GHSIAANVNSP 1600
C ++ Q S L H L T+ + K E G GH I N P
Sbjct: 141 ECGTSFYQFSYLTRHK---LIHTREKPYKCEQYGKTFNQSSTLTGHKIIHNGEKP 192
Score = 36.2 bits (82), Expect = 0.60
Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 4/105 (3%)
Query: 614 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 673
+C +C L H ++H+ K KC +C +K TL H E
Sbjct: 306 KCEECGKTFSVFSILTKHK-IIHTEE--KPYKCEECGKAFKRSSTLTKHRIIHTEEKPYK 362
Query: 674 CVYC-KTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIH 717
C C K L+ + G KP++CE C + L+IH
Sbjct: 363 CEECGKAFNQSSTLSIHKIIHTGEKPYKCEECGKAFKRSSTLTIH 407
Score = 34.3 bits (77), Expect = 2.3
Identities = 26/105 (24%), Positives = 39/105 (37%), Gaps = 4/105 (3%)
Query: 614 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 673
+C +C +L H ++H+ K KC KC + L H E
Sbjct: 530 KCEECGKAFSIFSTLTKHK-IIHTEE--KPYKCEKCGKTFYRFSNLNTHKIIHTGEKPCK 586
Query: 674 CVYCKTGQPHP-RLARGESYTCGYKPFRCEVCNYSTTTKGNLSIH 717
C C H L + + G KP++CE C + +LS H
Sbjct: 587 CEECGKAFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRH 631
Score = 33.9 bits (76), Expect = 3.0
Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 9/77 (11%)
Query: 2227 VWFQNARQKAR-----KSYENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFD 2281
+WF + R KSY+ + N+ LT + I T Y+C++C F +
Sbjct: 92 IWFSTLTRHRRVHTGEKSYKYECGKSFNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSY 151
Query: 2282 L----ITHQKKQCYKDE 2294
L + H +++ YK E
Sbjct: 152 LTRHKLIHTREKPYKCE 168
Score = 32.7 bits (73), Expect = 6.6
Identities = 25/107 (23%), Positives = 38/107 (35%), Gaps = 4/107 (3%)
Query: 614 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 673
+C +C S L H + K KC +C + TL H +
Sbjct: 418 KCEECGKAFNRSSHLTTHKRI---HTGHKPYKCKECGKSFSVFSTLTKHKIIHTDKKPYK 474
Query: 674 CVYC-KTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQ 719
C C K L+ + G KP++CE C + +L+ H Q
Sbjct: 475 CEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSHLAGHKQ 521
>gi|115511044 zinc finger protein 493 isoform 3 [Homo sapiens]
Length = 774
Score = 74.7 bits (182), Expect = 2e-12
Identities = 70/267 (26%), Positives = 112/267 (41%), Gaps = 33/267 (12%)
Query: 1352 YRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAEL 1411
+RC C A+K L H + H C C ++F F L KH + H E +
Sbjct: 405 HRCEECGKAYKESSHLTTHKRIHTGEKPYKCEECGKTFSVFSILTKH-KIIHTEEKPYKC 463
Query: 1412 QQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPD-DMGS 1470
++ G+ + S T+++ H + E+ Y+ + GKA S S G
Sbjct: 464 EEC-------GKAFKRSSTLTK--HRIIHTEEKPYKCEECGKAFNQSSTLSIHKIIHTGE 514
Query: 1471 EPKRT----LPFRKGPNFTMEKFLDPS-RPYKCTVCKESFTQKNILLVHYNSVSHLHKLK 1525
+P + F++ T+ K + +PYKC C ++F + + L H + HK
Sbjct: 515 KPYKCEECGKAFKRSSTLTIHKMIHTGEKPYKCEECGKAFNRSSHLTTH-KRIHTGHKPY 573
Query: 1526 KVLQ-----EASSPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAK 1580
K + S + + +TD KPYKC C A+++SS L IH + +H T + K
Sbjct: 574 KCKECGKSFSVFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILSIHKK--IH-TGEKPYK 630
Query: 1581 LEPSG-------HVAGGHSIAANVNSP 1600
E G H+A GH +V P
Sbjct: 631 CEECGKAFKRSSHLA-GHKQIHSVQKP 656
Score = 57.8 bits (138), Expect = 2e-07
Identities = 59/246 (23%), Positives = 93/246 (37%), Gaps = 27/246 (10%)
Query: 1352 YRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAEL 1411
Y+C F L H H C C ++F F KH + H E
Sbjct: 293 YKCEQYGKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKH-KIIHTEEKSHRC 351
Query: 1412 QQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMGSE 1471
++ A E+ H E+ Y+ + GKA + S + E
Sbjct: 352 EEYCK---------AYKESSHLTTHKRIHTGEKPYKCEECGKAFSIFSTLTKHKIIHTEE 402
Query: 1472 PKRTLP-----FRKGPNFTMEKFLDPS-RPYKCTVCKESFTQKNILLVHYNSVSHLHKLK 1525
+++ + T K + +PYKC C ++F+ +IL H + H +
Sbjct: 403 KSHRCEECGKAYKESSHLTTHKRIHTGEKPYKCEECGKTFSVFSILTKH--KIIHTEEKP 460
Query: 1526 KVLQEA------SSPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAA 1579
+E SS + + +T+ KPYKC C A++QSSTL IH ++H T +
Sbjct: 461 YKCEECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFNQSSTLSIH--KIIH-TGEKPY 517
Query: 1580 KLEPSG 1585
K E G
Sbjct: 518 KCEECG 523
Score = 56.2 bits (134), Expect = 6e-07
Identities = 61/250 (24%), Positives = 96/250 (38%), Gaps = 35/250 (14%)
Query: 1352 YRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKH--LEAGHPELSEA 1409
Y+C C AFK L H H C C ++F L H + G
Sbjct: 461 YKCEECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFNQSSTLSIHKIIHTGEKPYKCE 520
Query: 1410 ELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPD-DM 1468
E G+ + S T++ H + E+ Y+ + GKA S ++
Sbjct: 521 EC----------GKAFKRSSTLTI--HKMIHTGEKPYKCEECGKAFNRSSHLTTHKRIHT 568
Query: 1469 GSEPKRTLPFRKG----PNFTMEKFLDPSR-PYKCTVCKESFTQKNILLVHYNSVSHLHK 1523
G +P + K T K + + PYKC C ++F + +IL +H +H
Sbjct: 569 GHKPYKCKECGKSFSVFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILSIH----KKIHT 624
Query: 1524 LKKVLQ--------EASSPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTK 1575
+K + + SS + ++ KPYKC C A+S STL H ++H T+
Sbjct: 625 GEKPYKCEECGKAFKRSSHLAGHKQIHSVQKPYKCEECGKAFSIFSTLTKH--KIIH-TE 681
Query: 1576 ARAAKLEPSG 1585
+ K E G
Sbjct: 682 EKPYKCEKCG 691
Score = 55.5 bits (132), Expect = 1e-06
Identities = 59/240 (24%), Positives = 94/240 (39%), Gaps = 43/240 (17%)
Query: 1352 YRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKH--LEAGHPELSEA 1409
Y+C C AFK L IH H C C ++F L H + GH
Sbjct: 517 YKCEECGKAFKRSSTLTIHKMIHTGEKPYKCEECGKAFNRSSHLTTHKRIHTGHKPYKCK 576
Query: 1410 ELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMG 1469
E G+ ++ T+++ H + ++ Y+ + GKA + SSI
Sbjct: 577 EC----------GKSFSVFSTLTK--HKIIHTDKKPYKCEECGKAF----NRSSI----- 615
Query: 1470 SEPKRTLPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVH--YNSVSHLHKLKKV 1527
L K K +PYKC C ++F + + L H +SV +K ++
Sbjct: 616 ------LSIHK-------KIHTGEKPYKCEECGKAFKRSSHLAGHKQIHSVQKPYKCEEC 662
Query: 1528 LQEAS--SPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSG 1585
+ S S + + +T+ KPYKC C + + S L H ++H T + K E G
Sbjct: 663 GKAFSIFSTLTKHKIIHTEEKPYKCEKCGKTFYRFSNLNTH--KIIH-TGEKPCKCEECG 719
Score = 54.7 bits (130), Expect = 2e-06
Identities = 55/228 (24%), Positives = 86/228 (37%), Gaps = 26/228 (11%)
Query: 1352 YRCNHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAEL 1411
Y+C C AF L H + H C C +SF F L KH + H + +
Sbjct: 545 YKCEECGKAFNRSSHLTTHKRIHTGHKPYKCKECGKSFSVFSTLTKH-KIIHTDKKPYKC 603
Query: 1412 QQLYASLPVNGELWAESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMGSE 1471
++ G+ + S +S H E+ Y+ + GKA S + + S
Sbjct: 604 EEC-------GKAFNRSSILSI--HKKIHTGEKPYKCEECGKAFKRSSHLAG-HKQIHSV 653
Query: 1472 PKRTLPFRKGPNFTMEKFLDP-------SRPYKCTVCKESFTQKNILLVHYNSVSHLHKL 1524
K G F++ L +PYKC C ++F + + L H + H +
Sbjct: 654 QKPYKCEECGKAFSIFSTLTKHKIIHTEEKPYKCEKCGKTFYRFSNLNTH--KIIHTGEK 711
Query: 1525 KKVLQEASSPVPQETNS------NTDNKPYKCSICNVAYSQSSTLEIH 1566
+E +N +T +KPYKC C A+ +SS L H
Sbjct: 712 PCKCEECGKAFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRH 759
Score = 40.8 bits (94), Expect = 0.024
Identities = 31/116 (26%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 614 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 673
+C + S +L GH + N K KC +C + T H E
Sbjct: 294 KCEQYGKTFNQSSTLTGHKII---HNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKSHR 350
Query: 674 CV-YCKTGQPHPRLARGESYTCGYKPFRCEVCN-----YSTTTKGNLSIHMQSDKH 723
C YCK + L + G KP++CE C +ST TK + IH + H
Sbjct: 351 CEEYCKAYKESSHLTTHKRIHTGEKPYKCEECGKAFSIFSTLTKHKI-IHTEEKSH 405
Score = 38.5 bits (88), Expect = 0.12
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 11/120 (9%)
Query: 1478 FRKGPNFTMEKFLDPS-RPYKCTVCKESFTQKNIL----LVHYNSVSH-LHKLKKVLQEA 1531
F + N T K + +PYKC C SF Q + L L+H + + K ++
Sbjct: 246 FNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQS 305
Query: 1532 SSPVPQETNSNTDNKPYKCSICNVAYSQSSTLE----IHMRSVLHQTKARAAKLEPSGHV 1587
S+ + N + KPYKC C A+S ST IH H+ + + S H+
Sbjct: 306 STLTGHKIIHNGE-KPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEEYCKAYKESSHL 364
Score = 37.7 bits (86), Expect = 0.21
Identities = 39/173 (22%), Positives = 63/173 (36%), Gaps = 16/173 (9%)
Query: 614 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 673
+C +C S +L H ++H+ K KC +C + TL H E
Sbjct: 462 KCEECGKAFKRSSTLTKHR-IIHTEE--KPYKCEECGKAFNQSSTLSIHKIIHTGEKPYK 518
Query: 674 CVYC-KTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQN 732
C C K + L + G KP++CE C + N S H+ + K ++
Sbjct: 519 CEECGKAFKRSSTLTIHKMIHTGEKPYKCEECGKAF----NRSSHLTTHKRIH------- 567
Query: 733 GNGEQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVARNLRIH 785
G + + + S+ T K ++CE C N + L IH
Sbjct: 568 -TGHKPYKCKECGKSFSVFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILSIH 619
Score = 36.6 bits (83), Expect = 0.46
Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 14/115 (12%)
Query: 1496 YKCTVCKESFTQKNILL----VHYNSVSHLHKLKKVLQEASSPVPQETNSNTDNKPYKCS 1551
Y+C C ++F + L VH S+ ++ K + S+ + +T KPYKC
Sbjct: 210 YRCEECGKAFIWFSTLTRHRRVHTGEKSYKYECGKSFNQDSN-LTTHKRIHTGQKPYKCE 268
Query: 1552 ICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAG------GHSIAANVNSP 1600
C ++ Q S L H L T+ + K E G GH I N P
Sbjct: 269 ECGTSFYQFSYLTRHK---LIHTREKPYKCEQYGKTFNQSSTLTGHKIIHNGEKP 320
Score = 36.2 bits (82), Expect = 0.60
Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 4/105 (3%)
Query: 614 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 673
+C +C L H ++H+ K KC +C +K TL H E
Sbjct: 434 KCEECGKTFSVFSILTKHK-IIHTEE--KPYKCEECGKAFKRSSTLTKHRIIHTEEKPYK 490
Query: 674 CVYC-KTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIH 717
C C K L+ + G KP++CE C + L+IH
Sbjct: 491 CEECGKAFNQSSTLSIHKIIHTGEKPYKCEECGKAFKRSSTLTIH 535
Score = 34.3 bits (77), Expect = 2.3
Identities = 26/105 (24%), Positives = 39/105 (37%), Gaps = 4/105 (3%)
Query: 614 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 673
+C +C +L H ++H+ K KC KC + L H E
Sbjct: 658 KCEECGKAFSIFSTLTKHK-IIHTEE--KPYKCEKCGKTFYRFSNLNTHKIIHTGEKPCK 714
Query: 674 CVYCKTGQPHP-RLARGESYTCGYKPFRCEVCNYSTTTKGNLSIH 717
C C H L + + G KP++CE C + +LS H
Sbjct: 715 CEECGKAFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRH 759
Score = 33.9 bits (76), Expect = 3.0
Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 9/77 (11%)
Query: 2227 VWFQNARQKAR-----KSYENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFD 2281
+WF + R KSY+ + N+ LT + I T Y+C++C F +
Sbjct: 220 IWFSTLTRHRRVHTGEKSYKYECGKSFNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSY 279
Query: 2282 L----ITHQKKQCYKDE 2294
L + H +++ YK E
Sbjct: 280 LTRHKLIHTREKPYKCE 296
Score = 32.7 bits (73), Expect = 6.6
Identities = 25/107 (23%), Positives = 38/107 (35%), Gaps = 4/107 (3%)
Query: 614 ECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGS 673
+C +C S L H + K KC +C + TL H +
Sbjct: 546 KCEECGKAFNRSSHLTTHKRI---HTGHKPYKCKECGKSFSVFSTLTKHKIIHTDKKPYK 602
Query: 674 CVYC-KTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQ 719
C C K L+ + G KP++CE C + +L+ H Q
Sbjct: 603 CEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSHLAGHKQ 649
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 74.7 bits (182), Expect = 2e-12
Identities = 39/88 (44%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 1952 PSSPETPPPPPP-----PPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
PS P T PPPPP PPP APP P + + P+T+S+P PP PP PP
Sbjct: 164 PSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAF 223
Query: 2007 PPPPPPPPPPSAPPQVQLPVSLDLPLFP 2034
PPPPP P APP P ++ LFP
Sbjct: 224 LAPPPPPVPAPAPPAPASPHTVGTRLFP 251
Score = 63.9 bits (154), Expect = 3e-09
Identities = 36/88 (40%), Positives = 43/88 (48%), Gaps = 17/88 (19%)
Query: 1952 PSSPETPPPPPPPPPLPP---APPQPSSMGP--------VKIPNTVSTP-LQAPPPTPPP 1999
P P PP PP PP PP P SM P + P+T+S+P + PP PP
Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP 217
Query: 2000 PPP-----PPPPPPPPPPPPPPSAPPQV 2022
PP PPPPP P P PP P++P V
Sbjct: 218 APPLAFLAPPPPPVPAPAPPAPASPHTV 245
Score = 62.8 bits (151), Expect = 6e-09
Identities = 40/98 (40%), Positives = 45/98 (45%), Gaps = 13/98 (13%)
Query: 1961 PPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPP---PPPPPPPPPPPPPS 2017
PPPPP P PPQ S P +PL +PP T PPPPP PPPPP PPPP
Sbjct: 140 PPPPPGPAPGPPQDISEPPG------GSPLPSPPSTA-PPPPPLLLEPPPPPSMAPPPPP 192
Query: 2018 APPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLP 2055
+ P +L P P+ P P PP L P
Sbjct: 193 VLEALSPPHTLSSPSIPT---PPDFIPPAPPLAFLAPP 227
Score = 56.6 bits (135), Expect = 4e-07
Identities = 46/151 (30%), Positives = 60/151 (39%), Gaps = 26/151 (17%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008
P S P+ P P P L P +G + + + PP PP PPP PP P
Sbjct: 348 PASQVYPDRAPEPDCPGELKATAPASPRLGQSQ---SQADERAGTPPPAPPLPPPAPPLP 404
Query: 2009 PPPPPPPPSAPPQVQLPVS----------LDLPLFPSIMMQPVQHPALPPQLALQLP--- 2055
PP PP PP+APP LP + P S ++P +P P A P
Sbjct: 405 PPAPPLPPAAPP---LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDW 461
Query: 2056 ----QMDALSADL-TQLCQQQLGLDPNFLRH 2081
QM+ L +L LC + + FL H
Sbjct: 462 RDPSQMEKLRNELAAYLCGSR--REDRFLSH 490
Score = 50.1 bits (118), Expect = 4e-05
Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 14/140 (10%)
Query: 1945 DKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVST------PLQAPPPTPP 1998
D + P P + PPPPP P P PPAP P ++G P T L
Sbjct: 213 DFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272
Query: 1999 PPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMD 2058
PP P P P+ P + P S +P PV+ ++P Q A + P+ +
Sbjct: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVP-----PPTPVRTSSIPVQEAQEAPRKE 327
Query: 2059 ALSADLTQLCQQQLGLDPNF 2078
T+ +L L P+F
Sbjct: 328 ---EGATKKAPSRLPLPPSF 344
Score = 45.4 bits (106), Expect = 0.001
Identities = 33/86 (38%), Positives = 41/86 (47%), Gaps = 15/86 (17%)
Query: 3054 PGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPL 3113
PG G ++ P GP+ PG PQ+ + PPG L P S ++ P PL
Sbjct: 130 PGQYGQDLLIPPPPPGPA--PGPPQDISE--PPGGSPLPSPPS---------TAPPPPPL 176
Query: 3114 LQTPPPPPP--PPPPPPSSSLSGQQT 3137
L PPPPP PPPPP +LS T
Sbjct: 177 LLEPPPPPSMAPPPPPVLEALSPPHT 202
Score = 43.5 bits (101), Expect = 0.004
Identities = 31/86 (36%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 3046 GISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSL 3105
G LP+ P PP+LL PS P P L+PP L P+ T P +
Sbjct: 160 GSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHT--LSSPSIPT--PPDFI 215
Query: 3106 SSAPTKPLLQTPPPPPPPPPPPPSSS 3131
AP L PPPP P P PP +S
Sbjct: 216 PPAPPLAFLAPPPPPVPAPAPPAPAS 241
Score = 42.0 bits (97), Expect = 0.011
Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 16/123 (13%)
Query: 3084 TPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKE 3143
T P + LG S A + AP P P PPP PP PP + L Q
Sbjct: 369 TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQ------- 421
Query: 3144 SEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQLQALQN 3203
K P K + A KP+ +P E +S+ V + DP Q++ L+N
Sbjct: 422 --KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWR-------DPSQMEKLRN 472
Query: 3204 AIA 3206
+A
Sbjct: 473 ELA 475
Score = 40.8 bits (94), Expect = 0.024
Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 4/110 (3%)
Query: 2334 PAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDP 2393
PA S P SP P P T+P P +P P PPS P L + S
Sbjct: 146 PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP----PPPPSMAPPPPPVLEALSPPH 201
Query: 2394 PQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
+S + P P P P L P P P+ P S ++ L P
Sbjct: 202 TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFP 251
Score = 40.8 bits (94), Expect = 0.024
Identities = 34/132 (25%), Positives = 50/132 (37%), Gaps = 20/132 (15%)
Query: 2326 DAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTS----PKPEYPAEKPKQSDPSPPSQGTK 2381
D A P + ++P + + + ++ + P P P P P+PP
Sbjct: 355 DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAA 414
Query: 2382 PALPLASTSSDPPQASTAQPQ-------PQPQPPKQPQLIGRPPSASQTPVP-SSPLQIS 2433
P LP A ++ PP T P+ P+P PP +AS PV P Q
Sbjct: 415 PPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPEN------TASSAPVDWRDPSQ-- 466
Query: 2434 MTSLQNSLPPQL 2445
M L+N L L
Sbjct: 467 MEKLRNELAAYL 478
Score = 35.8 bits (81), Expect = 0.78
Identities = 23/84 (27%), Positives = 31/84 (36%), Gaps = 9/84 (10%)
Query: 2346 LIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQP 2405
LIP P P P +P P +P P P T P P PP + P
Sbjct: 138 LIPPPPPGP---APGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA------P 188
Query: 2406 QPPKQPQLIGRPPSASQTPVPSSP 2429
PP + + P + S +P+ P
Sbjct: 189 PPPPVLEALSPPHTLSSPSIPTPP 212
Score = 34.3 bits (77), Expect = 2.3
Identities = 37/158 (23%), Positives = 54/158 (34%), Gaps = 38/158 (24%)
Query: 2324 QTDAAKNAAAPAASSGSGTSTPLIPS-----PKPEPEKTSPK-----PEYPA-------- 2365
++D A N A+ S +P P P PEP T P+ P P
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
Query: 2366 ---EKPKQSD----------PSPPSQGTKPALPLASTSSDPPQ-------ASTAQPQPQP 2405
E P++ + P PPS +PA + + P + A P+
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQ 378
Query: 2406 QPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
+ + G PP A P P+ PL L + PP
Sbjct: 379 SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
Score = 34.3 bits (77), Expect = 2.3
Identities = 29/100 (29%), Positives = 35/100 (35%), Gaps = 7/100 (7%)
Query: 2333 APAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQ--GTKPALPLASTS 2390
AP G+ T PS P P +P + +P P + T PA P S
Sbjct: 323 APRKEEGA---TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS 379
Query: 2391 SDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPL 2430
QA P P PP P PP A P + PL
Sbjct: 380 QS--QADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL 417
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 74.7 bits (182), Expect = 2e-12
Identities = 39/88 (44%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 1952 PSSPETPPPPPP-----PPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
PS P T PPPPP PPP APP P + + P+T+S+P PP PP PP
Sbjct: 164 PSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAF 223
Query: 2007 PPPPPPPPPPSAPPQVQLPVSLDLPLFP 2034
PPPPP P APP P ++ LFP
Sbjct: 224 LAPPPPPVPAPAPPAPASPHTVGTRLFP 251
Score = 63.9 bits (154), Expect = 3e-09
Identities = 36/88 (40%), Positives = 43/88 (48%), Gaps = 17/88 (19%)
Query: 1952 PSSPETPPPPPPPPPLPP---APPQPSSMGP--------VKIPNTVSTP-LQAPPPTPPP 1999
P P PP PP PP PP P SM P + P+T+S+P + PP PP
Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP 217
Query: 2000 PPP-----PPPPPPPPPPPPPPSAPPQV 2022
PP PPPPP P P PP P++P V
Sbjct: 218 APPLAFLAPPPPPVPAPAPPAPASPHTV 245
Score = 62.8 bits (151), Expect = 6e-09
Identities = 40/98 (40%), Positives = 45/98 (45%), Gaps = 13/98 (13%)
Query: 1961 PPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPP---PPPPPPPPPPPPPS 2017
PPPPP P PPQ S P +PL +PP T PPPPP PPPPP PPPP
Sbjct: 140 PPPPPGPAPGPPQDISEPPG------GSPLPSPPSTA-PPPPPLLLEPPPPPSMAPPPPP 192
Query: 2018 APPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLP 2055
+ P +L P P+ P P PP L P
Sbjct: 193 VLEALSPPHTLSSPSIPT---PPDFIPPAPPLAFLAPP 227
Score = 56.6 bits (135), Expect = 4e-07
Identities = 46/151 (30%), Positives = 60/151 (39%), Gaps = 26/151 (17%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008
P S P+ P P P L P +G + + + PP PP PPP PP P
Sbjct: 348 PASQVYPDRAPEPDCPGELKATAPASPRLGQSQ---SQADERAGTPPPAPPLPPPAPPLP 404
Query: 2009 PPPPPPPPSAPPQVQLPVS----------LDLPLFPSIMMQPVQHPALPPQLALQLP--- 2055
PP PP PP+APP LP + P S ++P +P P A P
Sbjct: 405 PPAPPLPPAAPP---LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDW 461
Query: 2056 ----QMDALSADL-TQLCQQQLGLDPNFLRH 2081
QM+ L +L LC + + FL H
Sbjct: 462 RDPSQMEKLRNELAAYLCGSR--REDRFLSH 490
Score = 50.1 bits (118), Expect = 4e-05
Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 14/140 (10%)
Query: 1945 DKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVST------PLQAPPPTPP 1998
D + P P + PPPPP P P PPAP P ++G P T L
Sbjct: 213 DFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272
Query: 1999 PPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMD 2058
PP P P P+ P + P S +P PV+ ++P Q A + P+ +
Sbjct: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVP-----PPTPVRTSSIPVQEAQEAPRKE 327
Query: 2059 ALSADLTQLCQQQLGLDPNF 2078
T+ +L L P+F
Sbjct: 328 ---EGATKKAPSRLPLPPSF 344
Score = 45.4 bits (106), Expect = 0.001
Identities = 33/86 (38%), Positives = 41/86 (47%), Gaps = 15/86 (17%)
Query: 3054 PGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPL 3113
PG G ++ P GP+ PG PQ+ + PPG L P S ++ P PL
Sbjct: 130 PGQYGQDLLIPPPPPGPA--PGPPQDISE--PPGGSPLPSPPS---------TAPPPPPL 176
Query: 3114 LQTPPPPPP--PPPPPPSSSLSGQQT 3137
L PPPPP PPPPP +LS T
Sbjct: 177 LLEPPPPPSMAPPPPPVLEALSPPHT 202
Score = 43.5 bits (101), Expect = 0.004
Identities = 31/86 (36%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 3046 GISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSL 3105
G LP+ P PP+LL PS P P L+PP L P+ T P +
Sbjct: 160 GSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHT--LSSPSIPT--PPDFI 215
Query: 3106 SSAPTKPLLQTPPPPPPPPPPPPSSS 3131
AP L PPPP P P PP +S
Sbjct: 216 PPAPPLAFLAPPPPPVPAPAPPAPAS 241
Score = 42.0 bits (97), Expect = 0.011
Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 16/123 (13%)
Query: 3084 TPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKE 3143
T P + LG S A + AP P P PPP PP PP + L Q
Sbjct: 369 TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQ------- 421
Query: 3144 SEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQLQALQN 3203
K P K + A KP+ +P E +S+ V + DP Q++ L+N
Sbjct: 422 --KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWR-------DPSQMEKLRN 472
Query: 3204 AIA 3206
+A
Sbjct: 473 ELA 475
Score = 40.8 bits (94), Expect = 0.024
Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 4/110 (3%)
Query: 2334 PAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDP 2393
PA S P SP P P T+P P +P P PPS P L + S
Sbjct: 146 PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP----PPPPSMAPPPPPVLEALSPPH 201
Query: 2394 PQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
+S + P P P P L P P P+ P S ++ L P
Sbjct: 202 TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFP 251
Score = 40.8 bits (94), Expect = 0.024
Identities = 34/132 (25%), Positives = 50/132 (37%), Gaps = 20/132 (15%)
Query: 2326 DAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTS----PKPEYPAEKPKQSDPSPPSQGTK 2381
D A P + ++P + + + ++ + P P P P P+PP
Sbjct: 355 DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAA 414
Query: 2382 PALPLASTSSDPPQASTAQPQ-------PQPQPPKQPQLIGRPPSASQTPVP-SSPLQIS 2433
P LP A ++ PP T P+ P+P PP +AS PV P Q
Sbjct: 415 PPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPEN------TASSAPVDWRDPSQ-- 466
Query: 2434 MTSLQNSLPPQL 2445
M L+N L L
Sbjct: 467 MEKLRNELAAYL 478
Score = 35.8 bits (81), Expect = 0.78
Identities = 23/84 (27%), Positives = 31/84 (36%), Gaps = 9/84 (10%)
Query: 2346 LIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQP 2405
LIP P P P +P P +P P P T P P PP + P
Sbjct: 138 LIPPPPPGP---APGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA------P 188
Query: 2406 QPPKQPQLIGRPPSASQTPVPSSP 2429
PP + + P + S +P+ P
Sbjct: 189 PPPPVLEALSPPHTLSSPSIPTPP 212
Score = 34.3 bits (77), Expect = 2.3
Identities = 37/158 (23%), Positives = 54/158 (34%), Gaps = 38/158 (24%)
Query: 2324 QTDAAKNAAAPAASSGSGTSTPLIPS-----PKPEPEKTSPK-----PEYPA-------- 2365
++D A N A+ S +P P P PEP T P+ P P
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
Query: 2366 ---EKPKQSD----------PSPPSQGTKPALPLASTSSDPPQ-------ASTAQPQPQP 2405
E P++ + P PPS +PA + + P + A P+
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQ 378
Query: 2406 QPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
+ + G PP A P P+ PL L + PP
Sbjct: 379 SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
Score = 34.3 bits (77), Expect = 2.3
Identities = 29/100 (29%), Positives = 35/100 (35%), Gaps = 7/100 (7%)
Query: 2333 APAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQ--GTKPALPLASTS 2390
AP G+ T PS P P +P + +P P + T PA P S
Sbjct: 323 APRKEEGA---TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS 379
Query: 2391 SDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPL 2430
QA P P PP P PP A P + PL
Sbjct: 380 QS--QADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL 417
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 74.7 bits (182), Expect = 2e-12
Identities = 39/88 (44%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 1952 PSSPETPPPPPP-----PPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006
PS P T PPPPP PPP APP P + + P+T+S+P PP PP PP
Sbjct: 164 PSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAF 223
Query: 2007 PPPPPPPPPPSAPPQVQLPVSLDLPLFP 2034
PPPPP P APP P ++ LFP
Sbjct: 224 LAPPPPPVPAPAPPAPASPHTVGTRLFP 251
Score = 63.9 bits (154), Expect = 3e-09
Identities = 36/88 (40%), Positives = 43/88 (48%), Gaps = 17/88 (19%)
Query: 1952 PSSPETPPPPPPPPPLPP---APPQPSSMGP--------VKIPNTVSTP-LQAPPPTPPP 1999
P P PP PP PP PP P SM P + P+T+S+P + PP PP
Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP 217
Query: 2000 PPP-----PPPPPPPPPPPPPPSAPPQV 2022
PP PPPPP P P PP P++P V
Sbjct: 218 APPLAFLAPPPPPVPAPAPPAPASPHTV 245
Score = 62.8 bits (151), Expect = 6e-09
Identities = 40/98 (40%), Positives = 45/98 (45%), Gaps = 13/98 (13%)
Query: 1961 PPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPP---PPPPPPPPPPPPPS 2017
PPPPP P PPQ S P +PL +PP T PPPPP PPPPP PPPP
Sbjct: 140 PPPPPGPAPGPPQDISEPPG------GSPLPSPPSTA-PPPPPLLLEPPPPPSMAPPPPP 192
Query: 2018 APPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLP 2055
+ P +L P P+ P P PP L P
Sbjct: 193 VLEALSPPHTLSSPSIPT---PPDFIPPAPPLAFLAPP 227
Score = 56.6 bits (135), Expect = 4e-07
Identities = 46/151 (30%), Positives = 60/151 (39%), Gaps = 26/151 (17%)
Query: 1949 PISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPP 2008
P S P+ P P P L P +G + + + PP PP PPP PP P
Sbjct: 348 PASQVYPDRAPEPDCPGELKATAPASPRLGQSQ---SQADERAGTPPPAPPLPPPAPPLP 404
Query: 2009 PPPPPPPPSAPPQVQLPVS----------LDLPLFPSIMMQPVQHPALPPQLALQLP--- 2055
PP PP PP+APP LP + P S ++P +P P A P
Sbjct: 405 PPAPPLPPAAPP---LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDW 461
Query: 2056 ----QMDALSADL-TQLCQQQLGLDPNFLRH 2081
QM+ L +L LC + + FL H
Sbjct: 462 RDPSQMEKLRNELAAYLCGSR--REDRFLSH 490
Score = 50.1 bits (118), Expect = 4e-05
Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 14/140 (10%)
Query: 1945 DKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVST------PLQAPPPTPP 1998
D + P P + PPPPP P P PPAP P ++G P T L
Sbjct: 213 DFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272
Query: 1999 PPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMD 2058
PP P P P+ P + P S +P PV+ ++P Q A + P+ +
Sbjct: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVP-----PPTPVRTSSIPVQEAQEAPRKE 327
Query: 2059 ALSADLTQLCQQQLGLDPNF 2078
T+ +L L P+F
Sbjct: 328 ---EGATKKAPSRLPLPPSF 344
Score = 45.4 bits (106), Expect = 0.001
Identities = 33/86 (38%), Positives = 41/86 (47%), Gaps = 15/86 (17%)
Query: 3054 PGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSLSSAPTKPL 3113
PG G ++ P GP+ PG PQ+ + PPG L P S ++ P PL
Sbjct: 130 PGQYGQDLLIPPPPPGPA--PGPPQDISE--PPGGSPLPSPPS---------TAPPPPPL 176
Query: 3114 LQTPPPPPP--PPPPPPSSSLSGQQT 3137
L PPPPP PPPPP +LS T
Sbjct: 177 LLEPPPPPSMAPPPPPVLEALSPPHT 202
Score = 43.5 bits (101), Expect = 0.004
Identities = 31/86 (36%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 3046 GISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPTSATSSPALSL 3105
G LP+ P PP+LL PS P P L+PP L P+ T P +
Sbjct: 160 GSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHT--LSSPSIPT--PPDFI 215
Query: 3106 SSAPTKPLLQTPPPPPPPPPPPPSSS 3131
AP L PPPP P P PP +S
Sbjct: 216 PPAPPLAFLAPPPPPVPAPAPPAPAS 241
Score = 42.0 bits (97), Expect = 0.011
Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 16/123 (13%)
Query: 3084 TPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKE 3143
T P + LG S A + AP P P PPP PP PP + L Q
Sbjct: 369 TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQ------- 421
Query: 3144 SEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQLQALQN 3203
K P K + A KP+ +P E +S+ V + DP Q++ L+N
Sbjct: 422 --KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWR-------DPSQMEKLRN 472
Query: 3204 AIA 3206
+A
Sbjct: 473 ELA 475
Score = 40.8 bits (94), Expect = 0.024
Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 4/110 (3%)
Query: 2334 PAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDP 2393
PA S P SP P P T+P P +P P PPS P L + S
Sbjct: 146 PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP----PPPPSMAPPPPPVLEALSPPH 201
Query: 2394 PQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
+S + P P P P L P P P+ P S ++ L P
Sbjct: 202 TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFP 251
Score = 40.8 bits (94), Expect = 0.024
Identities = 34/132 (25%), Positives = 50/132 (37%), Gaps = 20/132 (15%)
Query: 2326 DAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTS----PKPEYPAEKPKQSDPSPPSQGTK 2381
D A P + ++P + + + ++ + P P P P P+PP
Sbjct: 355 DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAA 414
Query: 2382 PALPLASTSSDPPQASTAQPQ-------PQPQPPKQPQLIGRPPSASQTPVP-SSPLQIS 2433
P LP A ++ PP T P+ P+P PP +AS PV P Q
Sbjct: 415 PPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPEN------TASSAPVDWRDPSQ-- 466
Query: 2434 MTSLQNSLPPQL 2445
M L+N L L
Sbjct: 467 MEKLRNELAAYL 478
Score = 35.8 bits (81), Expect = 0.78
Identities = 23/84 (27%), Positives = 31/84 (36%), Gaps = 9/84 (10%)
Query: 2346 LIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQP 2405
LIP P P P +P P +P P P T P P PP + P
Sbjct: 138 LIPPPPPGP---APGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA------P 188
Query: 2406 QPPKQPQLIGRPPSASQTPVPSSP 2429
PP + + P + S +P+ P
Sbjct: 189 PPPPVLEALSPPHTLSSPSIPTPP 212
Score = 34.3 bits (77), Expect = 2.3
Identities = 37/158 (23%), Positives = 54/158 (34%), Gaps = 38/158 (24%)
Query: 2324 QTDAAKNAAAPAASSGSGTSTPLIPS-----PKPEPEKTSPK-----PEYPA-------- 2365
++D A N A+ S +P P P PEP T P+ P P
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
Query: 2366 ---EKPKQSD----------PSPPSQGTKPALPLASTSSDPPQ-------ASTAQPQPQP 2405
E P++ + P PPS +PA + + P + A P+
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQ 378
Query: 2406 QPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPP 2443
+ + G PP A P P+ PL L + PP
Sbjct: 379 SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
Score = 34.3 bits (77), Expect = 2.3
Identities = 29/100 (29%), Positives = 35/100 (35%), Gaps = 7/100 (7%)
Query: 2333 APAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQ--GTKPALPLASTS 2390
AP G+ T PS P P +P + +P P + T PA P S
Sbjct: 323 APRKEEGA---TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS 379
Query: 2391 SDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPL 2430
QA P P PP P PP A P + PL
Sbjct: 380 QS--QADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL 417
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 166,951,102
Number of Sequences: 37866
Number of extensions: 10057329
Number of successful extensions: 315655
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2567
Number of HSP's successfully gapped in prelim test: 1586
Number of HSP's that attempted gapping in prelim test: 72379
Number of HSP's gapped (non-prelim): 129433
length of query: 3571
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3449
effective length of database: 13,627,866
effective search space: 47002509834
effective search space used: 47002509834
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.