Search of human proteins with 125988411

Search of human proteins with 125988411

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|125988411 tetratricopeptide repeat domain 30B [Homo sapiens]
         (665 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|125988411 tetratricopeptide repeat domain 30B [Homo sapiens]      1337   0.0  
gi|145309317 tetratricopeptide repeat domain 30A [Homo sapiens]      1278   0.0  
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi...    40   0.009
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]            39   0.015
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]            39   0.015
gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]             39   0.015
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H...    39   0.020
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H...    39   0.020
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H...    36   0.100
gi|91825557 kinesin light chain 3 [Homo sapiens]                       35   0.22 
gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptid...    33   0.65 
gi|22749211 transmembrane and tetratricopeptide repeat containin...    33   0.65 
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [...    33   0.85 
gi|41871960 kinesin-like 8 isoform b [Homo sapiens]                    33   1.1  
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       33   1.1  
gi|41871955 kinesin-like 8 isoform a [Homo sapiens]                    33   1.1  
gi|41871946 kinesin-like 8 isoform a [Homo sapiens]                    33   1.1  
gi|17149828 NMDA receptor regulated 1 [Homo sapiens]                   32   1.9  
gi|14589860 aspartate beta-hydroxylase isoform c [Homo sapiens]        32   2.5  
gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens]        32   2.5  
gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens]        32   2.5  
gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]            32   2.5  
gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]            32   2.5  
gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]            32   2.5  
gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]             32   2.5  
gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]               31   3.2  
gi|21071052 helicase-like transcription factor [Homo sapiens]          31   3.2  
gi|21071054 helicase-like transcription factor [Homo sapiens]          31   3.2  
gi|4758416 golgi-specific brefeldin A resistant guanine nucleoti...    31   4.2  
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]                     31   4.2  

>gi|125988411 tetratricopeptide repeat domain 30B [Homo sapiens]
          Length = 665

 Score = 1337 bits (3459), Expect = 0.0
 Identities = 665/665 (100%), Positives = 665/665 (100%)

Query: 1   MAGLSGAQIPDGEFTAVVYRLIRNARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQE 60
           MAGLSGAQIPDGEFTAVVYRLIRNARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQE
Sbjct: 1   MAGLSGAQIPDGEFTAVVYRLIRNARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQE 60

Query: 61  FALAAECYEQLGQLHPELEQYRLYQAQALYKACLYAEATRVAFLLLDNPAYHSRVLRLQA 120
           FALAAECYEQLGQLHPELEQYRLYQAQALYKACLYAEATRVAFLLLDNPAYHSRVLRLQA
Sbjct: 61  FALAAECYEQLGQLHPELEQYRLYQAQALYKACLYAEATRVAFLLLDNPAYHSRVLRLQA 120

Query: 121 AIKYSEGDLPGSRSLVEQLPSREGGEESGGENETDGQINLGCLLYKEGQYEAACSKFFAA 180
           AIKYSEGDLPGSRSLVEQLPSREGGEESGGENETDGQINLGCLLYKEGQYEAACSKFFAA
Sbjct: 121 AIKYSEGDLPGSRSLVEQLPSREGGEESGGENETDGQINLGCLLYKEGQYEAACSKFFAA 180

Query: 181 LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGIDVRSVG 240
           LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGIDVRSVG
Sbjct: 181 LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGIDVRSVG 240

Query: 241 NTLVLHQTALVEAFNLKAAIEYQLRNYEAAQEALTDMPPRAEEELDPVTLHNQALMNMDA 300
           NTLVLHQTALVEAFNLKAAIEYQLRNYEAAQEALTDMPPRAEEELDPVTLHNQALMNMDA
Sbjct: 241 NTLVLHQTALVEAFNLKAAIEYQLRNYEAAQEALTDMPPRAEEELDPVTLHNQALMNMDA 300

Query: 301 RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLIYKFLTPYLYD 360
           RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLIYKFLTPYLYD
Sbjct: 301 RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLIYKFLTPYLYD 360

Query: 361 FLDAVITCQTAPEEAFIKLDGLAGMLTEVLRKLTIQVQEARHNRDDEAIKKAVNEYDETM 420
           FLDAVITCQTAPEEAFIKLDGLAGMLTEVLRKLTIQVQEARHNRDDEAIKKAVNEYDETM
Sbjct: 361 FLDAVITCQTAPEEAFIKLDGLAGMLTEVLRKLTIQVQEARHNRDDEAIKKAVNEYDETM 420

Query: 421 EKYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG 480
           EKYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG
Sbjct: 421 EKYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG 480

Query: 481 FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPDKKM 540
           FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPDKKM
Sbjct: 481 FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPDKKM 540

Query: 541 YHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH 600
           YHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH
Sbjct: 541 YHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH 600

Query: 601 TIMLRDSVIQECVQFLEHCELHGRNIPAVIEQPLEEERMHVGKNTVTYESRQLKALIYEI 660
           TIMLRDSVIQECVQFLEHCELHGRNIPAVIEQPLEEERMHVGKNTVTYESRQLKALIYEI
Sbjct: 601 TIMLRDSVIQECVQFLEHCELHGRNIPAVIEQPLEEERMHVGKNTVTYESRQLKALIYEI 660

Query: 661 IGWNI 665
           IGWNI
Sbjct: 661 IGWNI 665


>gi|145309317 tetratricopeptide repeat domain 30A [Homo sapiens]
          Length = 665

 Score = 1278 bits (3306), Expect = 0.0
 Identities = 634/664 (95%), Positives = 647/664 (97%)

Query: 1   MAGLSGAQIPDGEFTAVVYRLIRNARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQE 60
           MAGLSGAQIPDGEFTA+VYRLIR+ARYAEAVQLLG ELQRSPRSRAGLSLLGYCYYRLQE
Sbjct: 1   MAGLSGAQIPDGEFTALVYRLIRDARYAEAVQLLGRELQRSPRSRAGLSLLGYCYYRLQE 60

Query: 61  FALAAECYEQLGQLHPELEQYRLYQAQALYKACLYAEATRVAFLLLDNPAYHSRVLRLQA 120
           FALAAECYEQLGQLHPELEQYRLYQAQALYKACLY EATRVAFLLLDNPAYHSRVLRLQA
Sbjct: 61  FALAAECYEQLGQLHPELEQYRLYQAQALYKACLYPEATRVAFLLLDNPAYHSRVLRLQA 120

Query: 121 AIKYSEGDLPGSRSLVEQLPSREGGEESGGENETDGQINLGCLLYKEGQYEAACSKFFAA 180
           AIKYSEGDLPGSRSLVEQL S EGGEESGG+NETDGQ+NLGCLLYKEGQYEAACSKF A 
Sbjct: 121 AIKYSEGDLPGSRSLVEQLLSGEGGEESGGDNETDGQVNLGCLLYKEGQYEAACSKFSAT 180

Query: 181 LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGIDVRSVG 240
           LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEG DVRSVG
Sbjct: 181 LQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGFDVRSVG 240

Query: 241 NTLVLHQTALVEAFNLKAAIEYQLRNYEAAQEALTDMPPRAEEELDPVTLHNQALMNMDA 300
           NTLVLHQTALVEAFNLKAAIEYQLRNYE AQE LTDMPPRAEEELDPVTLHNQALMNMDA
Sbjct: 241 NTLVLHQTALVEAFNLKAAIEYQLRNYEVAQETLTDMPPRAEEELDPVTLHNQALMNMDA 300

Query: 301 RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLIYKFLTPYLYD 360
           RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHL YKFLTPYLYD
Sbjct: 301 RPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYD 360

Query: 361 FLDAVITCQTAPEEAFIKLDGLAGMLTEVLRKLTIQVQEARHNRDDEAIKKAVNEYDETM 420
           FLDA+ITCQTAPEEAFIKLDGLAGMLTE LR+LT QVQEARHNRDDEAIKKAVNEYDETM
Sbjct: 361 FLDALITCQTAPEEAFIKLDGLAGMLTEQLRRLTKQVQEARHNRDDEAIKKAVNEYDETM 420

Query: 421 EKYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG 480
           EKYIPVLMAQAKIYWNLENYPMVEK+FRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG
Sbjct: 421 EKYIPVLMAQAKIYWNLENYPMVEKVFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIG 480

Query: 481 FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPDKKM 540
           FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDP++KM
Sbjct: 481 FYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPNRKM 540

Query: 541 YHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH 600
           YHLCIVNLVIGTLYCAKGNY+FGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH
Sbjct: 541 YHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKH 600

Query: 601 TIMLRDSVIQECVQFLEHCELHGRNIPAVIEQPLEEERMHVGKNTVTYESRQLKALIYEI 660
            I++ DSVIQECVQFL HCEL+G NIPAVIEQPLEEERMHVGKNTVT ESRQLKALIYEI
Sbjct: 601 MIVIHDSVIQECVQFLGHCELYGTNIPAVIEQPLEEERMHVGKNTVTDESRQLKALIYEI 660

Query: 661 IGWN 664
           IGWN
Sbjct: 661 IGWN 664


>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
           protein) [Homo sapiens]
          Length = 543

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 51/214 (23%), Positives = 92/214 (42%), Gaps = 46/214 (21%)

Query: 412 AVNEYDETME---KYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFC--NDHDVWKLNVAH 466
           A+  YD+  E     +  +  QA +Y+   +Y    ++  K++E    N  D  ++  A+
Sbjct: 244 ALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAY 303

Query: 467 VL----FMQENKYKEAIGFYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMR 522
                 + +E KYK+AI FY   + +H                 +  +  + ++AE    
Sbjct: 304 ARIGNSYFKEEKYKDAIHFYNKSLAEHR----------------TPDVLKKCQQAE---- 343

Query: 523 KIEKEEEQLSYDDPDKKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDT 582
           KI KE+E+L+Y +PD     L +     G     KG+Y   +    +++    K+   D 
Sbjct: 344 KILKEQERLAYINPD-----LALEEKNKGNECFQKGDYPQAMKHYTEAI----KRNPKDA 394

Query: 583 WYYAKR--CFLSLLENMSKHTIMLRDSVIQECVQ 614
             Y+ R  C+  LLE      + L+D   +EC+Q
Sbjct: 395 KLYSNRAACYTKLLE----FQLALKD--CEECIQ 422



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 24/81 (29%), Positives = 37/81 (45%)

Query: 27  YAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELEQYRLYQA 86
           Y +A++     ++R+P+     S    CY +L EF LA +  E+  QL P   +    +A
Sbjct: 376 YPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKA 435

Query: 87  QALYKACLYAEATRVAFLLLD 107
            AL     Y +A  V    LD
Sbjct: 436 AALEAMKDYTKAMDVYQKALD 456


>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
          Length = 618

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 13/132 (9%)

Query: 462 LNVAHVLFMQENKYKEAIGFYE---PIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAE 518
           LN+  +++  +NKYK+A         I +K         A  L NL V Y    + +EAE
Sbjct: 258 LNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAE 317

Query: 519 EL-MRKIEKEEEQLSYDDPD--KKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYN 575
            L  R +E  E+ L  D PD  K++ +L +       L   +G Y+       ++LE Y 
Sbjct: 318 PLCKRALEIREKVLGKDHPDVAKQLNNLAL-------LCQNQGKYEEVEYYYQRALEIYQ 370

Query: 576 KKLGTDTWYYAK 587
            KLG D    AK
Sbjct: 371 TKLGPDDPNVAK 382


>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
          Length = 573

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 13/132 (9%)

Query: 462 LNVAHVLFMQENKYKEAIGFYE---PIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAE 518
           LN+  +++  +NKYK+A         I +K         A  L NL V Y    + +EAE
Sbjct: 258 LNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAE 317

Query: 519 EL-MRKIEKEEEQLSYDDPD--KKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYN 575
            L  R +E  E+ L  D PD  K++ +L +       L   +G Y+       ++LE Y 
Sbjct: 318 PLCKRALEIREKVLGKDHPDVAKQLNNLAL-------LCQNQGKYEEVEYYYQRALEIYQ 370

Query: 576 KKLGTDTWYYAK 587
            KLG D    AK
Sbjct: 371 TKLGPDDPNVAK 382


>gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]
          Length = 560

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 13/132 (9%)

Query: 462 LNVAHVLFMQENKYKEAIGFYE---PIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAE 518
           LN+  +++  +NKYK+A         I +K         A  L NL V Y    + +EAE
Sbjct: 258 LNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAE 317

Query: 519 EL-MRKIEKEEEQLSYDDPD--KKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYN 575
            L  R +E  E+ L  D PD  K++ +L +       L   +G Y+       ++LE Y 
Sbjct: 318 PLCKRALEIREKVLGKDHPDVAKQLNNLAL-------LCQNQGKYEEVEYYYQRALEIYQ 370

Query: 576 KKLGTDTWYYAK 587
            KLG D    AK
Sbjct: 371 TKLGPDDPNVAK 382


>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
           sapiens]
          Length = 631

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 44/204 (21%), Positives = 79/204 (38%), Gaps = 10/204 (4%)

Query: 20  RLIRNARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELE 79
           +  +  +Y EA+      +   P +    +     Y+RL++FA+A         L+    
Sbjct: 142 KYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYT 201

Query: 80  QYRLYQAQALYKACLYAEAT----RVAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSL 135
           +    +  A +      EA     RV  L  +N    + + ++  A+   E   P    +
Sbjct: 202 KAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADI 261

Query: 136 VEQLPSREGG----EESGGENETDGQINLGCLLYKEGQYEAACSKFFAALQASGYQPDLS 191
           V  + S EG     E    + +   + + G   +KEG+YE A   +   + A G    L 
Sbjct: 262 V--IKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLP 319

Query: 192 YNLALAYYSSRQYASALKHIAEII 215
            N A+AY   ++Y  A K   + I
Sbjct: 320 ANRAMAYLKIQKYEEAEKDCTQAI 343


>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 44/204 (21%), Positives = 79/204 (38%), Gaps = 10/204 (4%)

Query: 20  RLIRNARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELE 79
           +  +  +Y EA+      +   P +    +     Y+RL++FA+A         L+    
Sbjct: 142 KYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYT 201

Query: 80  QYRLYQAQALYKACLYAEAT----RVAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSL 135
           +    +  A +      EA     RV  L  +N    + + ++  A+   E   P    +
Sbjct: 202 KAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADI 261

Query: 136 VEQLPSREGG----EESGGENETDGQINLGCLLYKEGQYEAACSKFFAALQASGYQPDLS 191
           V  + S EG     E    + +   + + G   +KEG+YE A   +   + A G    L 
Sbjct: 262 V--IKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLP 319

Query: 192 YNLALAYYSSRQYASALKHIAEII 215
            N A+AY   ++Y  A K   + I
Sbjct: 320 ANRAMAYLKIQKYEEAEKDCTQAI 343


>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
           sapiens]
          Length = 506

 Score = 36.2 bits (82), Expect = 0.100
 Identities = 40/169 (23%), Positives = 68/169 (40%), Gaps = 10/169 (5%)

Query: 55  YYRLQEFALAAECYEQLGQLHPELEQYRLYQAQALYKACLYAEAT----RVAFLLLDNPA 110
           Y+RL++FA+A         L+    +    +  A +      EA     RV  L  +N  
Sbjct: 18  YFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFE 77

Query: 111 YHSRVLRLQAAIKYSEGDLPGSRSLVEQLPSREGG----EESGGENETDGQINLGCLLYK 166
             + + ++  A+   E   P    +V  + S EG     E    + +   + + G   +K
Sbjct: 78  ATNELRKISQALASKENSYPKEADIV--IKSTEGERKQIEAQQNKQQAISEKDRGNGFFK 135

Query: 167 EGQYEAACSKFFAALQASGYQPDLSYNLALAYYSSRQYASALKHIAEII 215
           EG+YE A   +   + A G    L  N A+AY   ++Y  A K   + I
Sbjct: 136 EGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAI 184


>gi|91825557 kinesin light chain 3 [Homo sapiens]
          Length = 504

 Score = 35.0 bits (79), Expect = 0.22
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 6/104 (5%)

Query: 449 KSVEFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKHYDNI---LNVSAIVLANLC 505
           +S   C+      LN+  +++  +NKYKEA       ++     +       A  L NL 
Sbjct: 239 RSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLA 298

Query: 506 VSYIMTSQNEEAEEL-MRKIEKEEEQLSYDDPD--KKMYHLCIV 546
           V Y    +  EAE L  R +E  E+ L  D PD  K++ +L ++
Sbjct: 299 VLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALL 342


>gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptide
           [Homo sapiens]
          Length = 1445

 Score = 33.5 bits (75), Expect = 0.65
 Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 14/79 (17%)

Query: 405 DDEAIKKAVNEYDETME----KYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFCNDHDVW 460
           D E  K AV + D  +     +Y+P L+   K  WNLE+ P+V+ +  +S++        
Sbjct: 734 DQEIRKVAVQQLDNLLNDELLEYLPQLVQAVKFEWNLES-PLVQLLLHRSLQ-------- 784

Query: 461 KLNVAHVLF-MQENKYKEA 478
            + VAH L+ + +N   EA
Sbjct: 785 SIQVAHRLYWLLKNAENEA 803


>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
           [Homo sapiens]
          Length = 836

 Score = 33.5 bits (75), Expect = 0.65
 Identities = 44/196 (22%), Positives = 73/196 (37%), Gaps = 29/196 (14%)

Query: 159 NLGCLLYKEGQYEAACSKFFAALQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERG 218
           NLG +L  + +   A S +  AL       D+ YNL L    + ++A AL +     +  
Sbjct: 498 NLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHY----YKLA 553

Query: 219 IRQHPELGVGMTTEGIDVRSVGNTLVLHQTAL----VEAFNLK----------------A 258
           I   P L       GI + + G T    +T L    +   NLK                 
Sbjct: 554 IGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYNLG 613

Query: 259 AIEYQLRNYEAAQEALTDMPPRAEEELDPVTLHN---QALMNMDARPTEGFEKLQFLLQQ 315
            + ++  +YE A     +   +   +  P +L+N   +A M +   P      ++ L  +
Sbjct: 614 KLYHEQGHYEEALSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSK 673

Query: 316 NPFPPE--TFGNLLLL 329
               P   T+G LL L
Sbjct: 674 TDHIPAHLTYGKLLAL 689


>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
            sapiens]
          Length = 2564

 Score = 33.1 bits (74), Expect = 0.85
 Identities = 48/175 (27%), Positives = 73/175 (41%), Gaps = 17/175 (9%)

Query: 58   LQEFALAAECYE-QLGQLHPELEQYRLY------QAQALYKACLYAEATRVAFLLLDNPA 110
            L+E AL AE +  Q  +LH   E+           AQA  +A   A A R+   L D  A
Sbjct: 1042 LEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAV--AAAGRLQRFLHDLDA 1099

Query: 111  YHSRVLRLQAAIKYSEGDLPGSRSLVEQLPSREGG--EESGGENETDGQINLGCLLYKEG 168
            +   ++R Q A   SEG LP S    + L +R     EE     E   +I    +   E 
Sbjct: 1100 FLDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARI----VAASEA 1155

Query: 169  QYEAACSKFFAALQASGYQP--DLSYNLALAYYSSRQYASALKHIAEIIERGIRQ 221
               A  ++    L    + P  +L ++  L  + +R+ A    HI ++  R +RQ
Sbjct: 1156 LLAADGAELGPGLALDEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRDLRQ 1210


>gi|41871960 kinesin-like 8 isoform b [Homo sapiens]
          Length = 637

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 13/126 (10%)

Query: 462 LNVAHVLFMQENKYKEAIGFYEPIVKKHYDNI---LNVSAIVLANLCVSYIMTSQNEEAE 518
           LN+  +++  +NKYKEA       +      +       A  L NL V Y    + +EAE
Sbjct: 274 LNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAE 333

Query: 519 EL-MRKIEKEEEQLSYDDPD--KKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYN 575
            L  R +E  E+ L  + PD  K++ +L +       L   +G Y+       ++L  Y 
Sbjct: 334 PLCQRALEIREKVLGTNHPDVAKQLNNLAL-------LCQNQGKYEAVERYYQRALAIYE 386

Query: 576 KKLGTD 581
            +LG D
Sbjct: 387 GQLGPD 392


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 14/40 (35%), Positives = 24/40 (60%)

Query: 101  VAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSLVEQLP 140
            V F++LDNP+    +L ++  I    G++P  RS +E+ P
Sbjct: 5523 VIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFP 5562


>gi|41871955 kinesin-like 8 isoform a [Homo sapiens]
          Length = 619

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 13/126 (10%)

Query: 462 LNVAHVLFMQENKYKEAIGFYEPIVKKHYDNI---LNVSAIVLANLCVSYIMTSQNEEAE 518
           LN+  +++  +NKYKEA       +      +       A  L NL V Y    + +EAE
Sbjct: 256 LNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAE 315

Query: 519 EL-MRKIEKEEEQLSYDDPD--KKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYN 575
            L  R +E  E+ L  + PD  K++ +L +       L   +G Y+       ++L  Y 
Sbjct: 316 PLCQRALEIREKVLGTNHPDVAKQLNNLAL-------LCQNQGKYEAVERYYQRALAIYE 368

Query: 576 KKLGTD 581
            +LG D
Sbjct: 369 GQLGPD 374


>gi|41871946 kinesin-like 8 isoform a [Homo sapiens]
          Length = 619

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 13/126 (10%)

Query: 462 LNVAHVLFMQENKYKEAIGFYEPIVKKHYDNI---LNVSAIVLANLCVSYIMTSQNEEAE 518
           LN+  +++  +NKYKEA       +      +       A  L NL V Y    + +EAE
Sbjct: 256 LNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAE 315

Query: 519 EL-MRKIEKEEEQLSYDDPD--KKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYN 575
            L  R +E  E+ L  + PD  K++ +L +       L   +G Y+       ++L  Y 
Sbjct: 316 PLCQRALEIREKVLGTNHPDVAKQLNNLAL-------LCQNQGKYEAVERYYQRALAIYE 368

Query: 576 KKLGTD 581
            +LG D
Sbjct: 369 GQLGPD 374


>gi|17149828 NMDA receptor regulated 1 [Homo sapiens]
          Length = 866

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 19/102 (18%)

Query: 38  LQRSPRSRAGLSLLGYC--YYRLQEFALAAECYEQLG---QLHPELEQYR-----LYQAQ 87
           LQ  P  RA  S +GY   Y+ L+++ +AA+  E+     Q  P+   Y      LYQ Q
Sbjct: 141 LQLRPAQRA--SWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQ 198

Query: 88  ALYKACLYAEATRVAFLLLDNPAYHSRVLRLQAAIKYSEGDL 129
            L +A LY EA       L++   + + +  + A++ ++G+L
Sbjct: 199 VLREAGLYREA-------LEHLCTYEKQICDKLAVEETKGEL 233


>gi|14589860 aspartate beta-hydroxylase isoform c [Homo sapiens]
          Length = 313

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 2/62 (3%)

Query: 598 SKHTIMLRDSVIQECVQFLEHCELHGRNIPAVIEQPLEEERMHVGKNTVTYESRQLKALI 657
           ++H+  + ++V Q+C Q +E       N P   E  +E+ER+H   + VTY+  + +A +
Sbjct: 208 TEHSYHVEETVSQDCNQDMEEMMSEQEN-PDSSEPVVEDERLHHDTDDVTYQVYEEQA-V 265

Query: 658 YE 659
           YE
Sbjct: 266 YE 267


>gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens]
          Length = 299

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 2/62 (3%)

Query: 598 SKHTIMLRDSVIQECVQFLEHCELHGRNIPAVIEQPLEEERMHVGKNTVTYESRQLKALI 657
           ++H+  + ++V Q+C Q +E       N P   E  +E+ER+H   + VTY+  + +A +
Sbjct: 194 TEHSYHVEETVSQDCNQDMEEMMSEQEN-PDSSEPVVEDERLHHDTDDVTYQVYEEQA-V 251

Query: 658 YE 659
           YE
Sbjct: 252 YE 253


>gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens]
          Length = 758

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 2/62 (3%)

Query: 598 SKHTIMLRDSVIQECVQFLEHCELHGRNIPAVIEQPLEEERMHVGKNTVTYESRQLKALI 657
           ++H+  + ++V Q+C Q +E       N P   E  +E+ER+H   + VTY+  + +A +
Sbjct: 208 TEHSYHVEETVSQDCNQDMEEMMSEQEN-PDSSEPVVEDERLHHDTDDVTYQVYEEQA-V 265

Query: 658 YE 659
           YE
Sbjct: 266 YE 267


>gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]
          Length = 622

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 21/136 (15%)

Query: 462 LNVAHVLFMQENKYKE-------AIGFYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQN 514
           LN+  +++  +NKYKE       A+   E  + K +  +    A  L NL V Y    + 
Sbjct: 243 LNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAV----AATLNNLAVLYGKRGKY 298

Query: 515 EEAEEL-MRKIEKEEEQLSYDDPD--KKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSL 571
           +EAE L  R +E  E+ L    PD  K++ +L ++    G     +  Y        ++L
Sbjct: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYR-------RAL 351

Query: 572 EPYNKKLGTDTWYYAK 587
           E Y  +LG D    AK
Sbjct: 352 EIYATRLGPDDPNVAK 367


>gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]
          Length = 622

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 21/136 (15%)

Query: 462 LNVAHVLFMQENKYKE-------AIGFYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQN 514
           LN+  +++  +NKYKE       A+   E  + K +  +    A  L NL V Y    + 
Sbjct: 243 LNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAV----AATLNNLAVLYGKRGKY 298

Query: 515 EEAEEL-MRKIEKEEEQLSYDDPD--KKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSL 571
           +EAE L  R +E  E+ L    PD  K++ +L ++    G     +  Y        ++L
Sbjct: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYR-------RAL 351

Query: 572 EPYNKKLGTDTWYYAK 587
           E Y  +LG D    AK
Sbjct: 352 EIYATRLGPDDPNVAK 367


>gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]
          Length = 545

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 21/136 (15%)

Query: 462 LNVAHVLFMQENKYKE-------AIGFYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQN 514
           LN+  +++  +NKYKE       A+   E  + K +  +    A  L NL V Y    + 
Sbjct: 166 LNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAV----AATLNNLAVLYGKRGKY 221

Query: 515 EEAEEL-MRKIEKEEEQLSYDDPD--KKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSL 571
           +EAE L  R +E  E+ L    PD  K++ +L ++    G     +  Y        ++L
Sbjct: 222 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYR-------RAL 274

Query: 572 EPYNKKLGTDTWYYAK 587
           E Y  +LG D    AK
Sbjct: 275 EIYATRLGPDDPNVAK 290


>gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]
          Length = 622

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 21/136 (15%)

Query: 462 LNVAHVLFMQENKYKE-------AIGFYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQN 514
           LN+  +++  +NKYKE       A+   E  + K +  +    A  L NL V Y    + 
Sbjct: 243 LNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAV----AATLNNLAVLYGKRGKY 298

Query: 515 EEAEEL-MRKIEKEEEQLSYDDPD--KKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSL 571
           +EAE L  R +E  E+ L    PD  K++ +L ++    G     +  Y        ++L
Sbjct: 299 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYR-------RAL 351

Query: 572 EPYNKKLGTDTWYYAK 587
           E Y  +LG D    AK
Sbjct: 352 EIYATRLGPDDPNVAK 367


>gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]
          Length = 545

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 4/71 (5%)

Query: 118 LQAAIKYSEGDLPGSRSLVEQLPSREGGEESGGENETDGQINLGCLLYKEGQYEAACSKF 177
           +Q A+  S GD+PG+R  VE +  ++   ESGG  +    I +G   Y   ++E + S  
Sbjct: 188 VQRAVAMSSGDVPGARGAVEGILIQQ-VFESGGSKKC---IQVGGEFYTPSKFEDSGSGK 243

Query: 178 FAALQASGYQP 188
             A  +SG +P
Sbjct: 244 NKARSSSGPKP 254


>gi|21071052 helicase-like transcription factor [Homo sapiens]
          Length = 1009

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 12/116 (10%)

Query: 472 ENKYKEAIGFY--EPIVKKHYDNILNVSAIVLANLCVSYIMT--------SQNEEAEELM 521
           +N+ +  IG Y  E  V  HY ++L +   +    C +Y++T        S N+  EEL 
Sbjct: 682 KNEGRATIGRYFNEGTVLAHYADVLGLLLRLRQICCHTYLLTNAVSSNGPSGNDTPEELR 741

Query: 522 RKIEKEEEQLSYDDPDKKMYHLCIVNLVIGTL-YCAKGNYDFGISRVIKSLEPYNK 576
           +K+ ++ + +     D++   +C+ +L +  + +CA       I +VI++ +P+ K
Sbjct: 742 KKLIRKMKLILSSGSDEEC-AICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAK 796


>gi|21071054 helicase-like transcription factor [Homo sapiens]
          Length = 1009

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 12/116 (10%)

Query: 472 ENKYKEAIGFY--EPIVKKHYDNILNVSAIVLANLCVSYIMT--------SQNEEAEELM 521
           +N+ +  IG Y  E  V  HY ++L +   +    C +Y++T        S N+  EEL 
Sbjct: 682 KNEGRATIGRYFNEGTVLAHYADVLGLLLRLRQICCHTYLLTNAVSSNGPSGNDTPEELR 741

Query: 522 RKIEKEEEQLSYDDPDKKMYHLCIVNLVIGTL-YCAKGNYDFGISRVIKSLEPYNK 576
           +K+ ++ + +     D++   +C+ +L +  + +CA       I +VI++ +P+ K
Sbjct: 742 KKLIRKMKLILSSGSDEEC-AICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAK 796


>gi|4758416 golgi-specific brefeldin A resistant guanine nucleotide
           exchange factor 1 [Homo sapiens]
          Length = 1859

 Score = 30.8 bits (68), Expect = 4.2
 Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 1/53 (1%)

Query: 60  EFALAAECYEQLGQLHPELEQYRLYQAQALYKACLYAEATRVAFLLLDNPAYH 112
           E A  A+C   LG +  E+ ++ L+Q  ++ +  LYA + RV FLL ++   H
Sbjct: 439 ESAPVAQCQTLLGLIKDEMCRH-LFQLLSIERLNLYAASLRVCFLLFESMREH 490


>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
          Length = 519

 Score = 30.8 bits (68), Expect = 4.2
 Identities = 17/57 (29%), Positives = 29/57 (50%)

Query: 159 NLGCLLYKEGQYEAACSKFFAALQASGYQPDLSYNLALAYYSSRQYASALKHIAEII 215
           N+G   + + +Y AA S    A   + +   + YNL L + + +QYASA   ++  I
Sbjct: 275 NIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAI 331


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,278,189
Number of Sequences: 37866
Number of extensions: 1063961
Number of successful extensions: 3525
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3488
Number of HSP's gapped (non-prelim): 62
length of query: 665
length of database: 18,247,518
effective HSP length: 109
effective length of query: 556
effective length of database: 14,120,124
effective search space: 7850788944
effective search space used: 7850788944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.