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Search of human proteins with 12597655
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12597655 centromere protein H [Homo sapiens]
(247 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|12597655 centromere protein H [Homo sapiens] 472 e-133
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 57 1e-08
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 52 5e-07
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 52 5e-07
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 52 5e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 49 4e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 49 4e-06
gi|156104908 myosin heavy chain 6 [Homo sapiens] 49 4e-06
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 49 4e-06
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 47 2e-05
gi|55770834 centromere protein F [Homo sapiens] 46 3e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 46 3e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 46 3e-05
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 46 3e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 46 3e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 46 3e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 46 3e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 46 3e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 46 3e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 46 3e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 46 3e-05
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] 45 6e-05
gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] 45 6e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 45 8e-05
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 45 8e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 44 1e-04
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 44 1e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 44 1e-04
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 44 1e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 44 1e-04
>gi|12597655 centromere protein H [Homo sapiens]
Length = 247
Score = 472 bits (1214), Expect = e-133
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 1 MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSM 60
MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSM
Sbjct: 1 MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSM 60
Query: 61 VDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKIS 120
VDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKIS
Sbjct: 61 VDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKIS 120
Query: 121 RQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKN 180
RQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKN
Sbjct: 121 RQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKN 180
Query: 181 KQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHVFQNLILGSKVNWAEDPALKEIVLQL 240
KQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHVFQNLILGSKVNWAEDPALKEIVLQL
Sbjct: 181 KQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHVFQNLILGSKVNWAEDPALKEIVLQL 240
Query: 241 EKNVDMM 247
EKNVDMM
Sbjct: 241 EKNVDMM 247
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 57.4 bits (137), Expect = 1e-08
Identities = 64/252 (25%), Positives = 115/252 (45%), Gaps = 37/252 (14%)
Query: 23 GGPPQVAGAQAACSEDRMTLL--------LRLRAQTKQQLLEYKSMVDASEEKTPEQIMQ 74
G ++ ++ C E R L LRL + Q+ + ++ + K+ + Q
Sbjct: 392 GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQ 451
Query: 75 -----EKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTA---LKKNLEKISRQSSVL 126
EK+ + +DL NE+E VK +K+L RL A LK +L K+ + +L
Sbjct: 452 LHLNLEKE-KNLTKDLLNELEVVKS--RVKELECSESRLEKAELSLKDDLTKLKSFTVML 508
Query: 127 MDNMKHLLE-----------LNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEI 175
+D K+++E LNK Q + D+ EKL++ KK L+LK E K+ +
Sbjct: 509 VDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNL 568
Query: 176 QTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHVFQNLI-----LGSKVNWAED 230
E+++ L S E E+ + ++ + K I+ V + + GS++ ED
Sbjct: 569 TRERDELIGKLKSEE--EKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPED 626
Query: 231 PALKEIVLQLEK 242
+KE+ L++E+
Sbjct: 627 NKIKELTLEIER 638
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 52.0 bits (123), Expect = 5e-07
Identities = 66/262 (25%), Positives = 115/262 (43%), Gaps = 29/262 (11%)
Query: 3 EQPQMQDADEPADSGGE----GRAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLL--- 55
E Q Q DE G E R + + +T L+ + + Q L
Sbjct: 416 EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKT 475
Query: 56 --EYKSMVDASEEKTPEQIMQEKQ---IEAKIEDLENEIEEVKVAFE-IKKLALDRMRLS 109
E ++ VD+ E + + EK+ + K+E LENEI + K + + + L+ D M+
Sbjct: 476 VEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEK 535
Query: 110 TALKKNLEKI----SRQSSVLMDNMKHLLELNKLIMKSQQESW-DLEEKLLDIRKKRLQL 164
L+K +E + RQ +L +H LN+ + +Q S E ++ DI K+ L
Sbjct: 536 AQLEKTIETLRENSERQIKILEQENEH---LNQTVSSLRQRSQISAEARVKDIEKENKIL 592
Query: 165 KQA---SESKLLEIQTEKNKQKIDLDS-MENSERIKIIRQNLQMEIKITTVIQHVFQNLI 220
++ + SKL +I+ EK + K +L+ E ER + + L K ++Q NL
Sbjct: 593 HESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL- 651
Query: 221 LGSKVNWAEDPALKEIVLQLEK 242
K+ + AL++ +LE+
Sbjct: 652 ---KITCEKIEALEQENSELER 670
Score = 42.7 bits (99), Expect = 3e-04
Identities = 49/178 (27%), Positives = 91/178 (51%), Gaps = 36/178 (20%)
Query: 48 AQTKQQLLEYKSMVDA---SEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFE------- 97
+Q ++ LE + V++ + K + ++ K++E++ E L+ +E +K +F+
Sbjct: 697 SQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEV 756
Query: 98 -IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLD 156
+ L ++ RL L+ + +KI + S L D L M++Q +LEE L
Sbjct: 757 SYQGLDIENQRLQKTLENSNKKIQQLESELQD----------LEMENQTLQKNLEE--LK 804
Query: 157 IRKKRLQLKQASESKLLEIQT---EKNKQKIDLDSMENSERIKIIRQNLQMEIKITTV 211
I KRL+ + E+K LE +T EK+K++++ ++ K +RQ Q EIK TT+
Sbjct: 805 ISSKRLEQLE-KENKSLEQETSQLEKDKKQLEKEN-------KRLRQ--QAEIKDTTL 852
Score = 40.0 bits (92), Expect = 0.002
Identities = 42/165 (25%), Positives = 83/165 (50%), Gaps = 25/165 (15%)
Query: 49 QTKQQLLEYKSMVD-------ASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKL 101
+ Q LLE K+M++ A +K E + Q++AK+ D+E E + + +I++L
Sbjct: 351 EDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRK--KIEEL 408
Query: 102 ALDRMRLSTALKKN----------LEKISRQSSVLMDNMKHL-LELNKL----IMKSQQE 146
+ M L A K++ LE+ISR S + K L E+N+L ++K + E
Sbjct: 409 MEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEME 468
Query: 147 SWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMEN 191
+ L + + ++R + + + SK+L+++ E + ++ +EN
Sbjct: 469 NQSLTKTVEELR-TTVDSVEGNASKILKMEKENQRLSKKVEILEN 512
Score = 39.7 bits (91), Expect = 0.002
Identities = 57/224 (25%), Positives = 108/224 (48%), Gaps = 30/224 (13%)
Query: 47 RAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEA-------------KIEDLENEIEEVK 93
+ Q K++L YK + +EE E EK+ E KIE LE E E++
Sbjct: 610 KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELE 669
Query: 94 VAFEIKKLALDRMRLSTALKKNLEK----ISRQSSVLMDNMKHLLELNKLIMKSQQESWD 149
K LD + T ++LEK + ++ L N++ L + + + Q E+ +
Sbjct: 670 RENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKE 729
Query: 150 LEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLD------SMENS-ERIKIIRQNL 202
LE + + KK L+L +AS K + E + Q +D++ ++ENS ++I+ + L
Sbjct: 730 LESEKEQL-KKGLELLKASFKKTERL--EVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786
Query: 203 Q-MEIKITTVIQHVFQNLILGSKVNW--AEDPALKEIVLQLEKN 243
Q +E++ T+ +++ + I ++ E+ +L++ QLEK+
Sbjct: 787 QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Score = 35.4 bits (80), Expect = 0.046
Identities = 39/164 (23%), Positives = 82/164 (50%), Gaps = 20/164 (12%)
Query: 51 KQQLLEYKSMVDASEEKTP-----------EQIMQEKQIE---AKIEDLENEIEEVKVAF 96
K+QL + ++ AS +KT E +K +E KI+ LE+E++++++
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793
Query: 97 EIKKLALDRMRLSTALKKNLEK----ISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEE 152
+ + L+ +++S+ + LEK + +++S L + K L + NK ++ Q E D
Sbjct: 794 QTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR-LRQQAEIKDTTL 852
Query: 153 KLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIK 196
+ +++ L+ + + SK + I E + +L+ EN E +K
Sbjct: 853 EENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK-ENKELVK 895
Score = 28.5 bits (62), Expect = 5.6
Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 39/162 (24%)
Query: 38 DRMTLLLRLRAQTKQQLLE-------YKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIE 90
++M + L+ Q LL Y+ +DA EK +++ LE+E+
Sbjct: 282 EQMEIELKRLQQENMNLLSDARSARMYRDELDALREKA-----------VRVDKLESEVS 330
Query: 91 EVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDL 150
K +R+ K +E++ + VL++ K +++ Q E
Sbjct: 331 RYK----------ERLHDIEFYKARVEELKEDNQVLLET--------KTMLEDQLEGTRA 372
Query: 151 E-EKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMEN 191
+KL ++ K+ LQLK +E++ + +++KI+ EN
Sbjct: 373 RSDKLHELEKENLQLKAKLHD--MEMERDMDRKKIEELMEEN 412
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 52.0 bits (123), Expect = 5e-07
Identities = 66/262 (25%), Positives = 115/262 (43%), Gaps = 29/262 (11%)
Query: 3 EQPQMQDADEPADSGGE----GRAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLL--- 55
E Q Q DE G E R + + +T L+ + + Q L
Sbjct: 416 EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKT 475
Query: 56 --EYKSMVDASEEKTPEQIMQEKQ---IEAKIEDLENEIEEVKVAFE-IKKLALDRMRLS 109
E ++ VD+ E + + EK+ + K+E LENEI + K + + + L+ D M+
Sbjct: 476 VEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEK 535
Query: 110 TALKKNLEKI----SRQSSVLMDNMKHLLELNKLIMKSQQESW-DLEEKLLDIRKKRLQL 164
L+K +E + RQ +L +H LN+ + +Q S E ++ DI K+ L
Sbjct: 536 AQLEKTIETLRENSERQIKILEQENEH---LNQTVSSLRQRSQISAEARVKDIEKENKIL 592
Query: 165 KQA---SESKLLEIQTEKNKQKIDLDS-MENSERIKIIRQNLQMEIKITTVIQHVFQNLI 220
++ + SKL +I+ EK + K +L+ E ER + + L K ++Q NL
Sbjct: 593 HESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL- 651
Query: 221 LGSKVNWAEDPALKEIVLQLEK 242
K+ + AL++ +LE+
Sbjct: 652 ---KITCEKIEALEQENSELER 670
Score = 42.7 bits (99), Expect = 3e-04
Identities = 49/178 (27%), Positives = 91/178 (51%), Gaps = 36/178 (20%)
Query: 48 AQTKQQLLEYKSMVDA---SEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFE------- 97
+Q ++ LE + V++ + K + ++ K++E++ E L+ +E +K +F+
Sbjct: 697 SQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEV 756
Query: 98 -IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLD 156
+ L ++ RL L+ + +KI + S L D L M++Q +LEE L
Sbjct: 757 SYQGLDIENQRLQKTLENSNKKIQQLESELQD----------LEMENQTLQKNLEE--LK 804
Query: 157 IRKKRLQLKQASESKLLEIQT---EKNKQKIDLDSMENSERIKIIRQNLQMEIKITTV 211
I KRL+ + E+K LE +T EK+K++++ ++ K +RQ Q EIK TT+
Sbjct: 805 ISSKRLEQLE-KENKSLEQETSQLEKDKKQLEKEN-------KRLRQ--QAEIKDTTL 852
Score = 40.0 bits (92), Expect = 0.002
Identities = 42/165 (25%), Positives = 83/165 (50%), Gaps = 25/165 (15%)
Query: 49 QTKQQLLEYKSMVD-------ASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKL 101
+ Q LLE K+M++ A +K E + Q++AK+ D+E E + + +I++L
Sbjct: 351 EDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRK--KIEEL 408
Query: 102 ALDRMRLSTALKKN----------LEKISRQSSVLMDNMKHL-LELNKL----IMKSQQE 146
+ M L A K++ LE+ISR S + K L E+N+L ++K + E
Sbjct: 409 MEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEME 468
Query: 147 SWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMEN 191
+ L + + ++R + + + SK+L+++ E + ++ +EN
Sbjct: 469 NQSLTKTVEELR-TTVDSVEGNASKILKMEKENQRLSKKVEILEN 512
Score = 39.7 bits (91), Expect = 0.002
Identities = 57/224 (25%), Positives = 108/224 (48%), Gaps = 30/224 (13%)
Query: 47 RAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEA-------------KIEDLENEIEEVK 93
+ Q K++L YK + +EE E EK+ E KIE LE E E++
Sbjct: 610 KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELE 669
Query: 94 VAFEIKKLALDRMRLSTALKKNLEK----ISRQSSVLMDNMKHLLELNKLIMKSQQESWD 149
K LD + T ++LEK + ++ L N++ L + + + Q E+ +
Sbjct: 670 RENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKE 729
Query: 150 LEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLD------SMENS-ERIKIIRQNL 202
LE + + KK L+L +AS K + E + Q +D++ ++ENS ++I+ + L
Sbjct: 730 LESEKEQL-KKGLELLKASFKKTERL--EVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786
Query: 203 Q-MEIKITTVIQHVFQNLILGSKVNW--AEDPALKEIVLQLEKN 243
Q +E++ T+ +++ + I ++ E+ +L++ QLEK+
Sbjct: 787 QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Score = 35.4 bits (80), Expect = 0.046
Identities = 39/164 (23%), Positives = 82/164 (50%), Gaps = 20/164 (12%)
Query: 51 KQQLLEYKSMVDASEEKTP-----------EQIMQEKQIE---AKIEDLENEIEEVKVAF 96
K+QL + ++ AS +KT E +K +E KI+ LE+E++++++
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMEN 793
Query: 97 EIKKLALDRMRLSTALKKNLEK----ISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEE 152
+ + L+ +++S+ + LEK + +++S L + K L + NK ++ Q E D
Sbjct: 794 QTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR-LRQQAEIKDTTL 852
Query: 153 KLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIK 196
+ +++ L+ + + SK + I E + +L+ EN E +K
Sbjct: 853 EENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK-ENKELVK 895
Score = 28.5 bits (62), Expect = 5.6
Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 39/162 (24%)
Query: 38 DRMTLLLRLRAQTKQQLLE-------YKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIE 90
++M + L+ Q LL Y+ +DA EK +++ LE+E+
Sbjct: 282 EQMEIELKRLQQENMNLLSDARSARMYRDELDALREKA-----------VRVDKLESEVS 330
Query: 91 EVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDL 150
K +R+ K +E++ + VL++ K +++ Q E
Sbjct: 331 RYK----------ERLHDIEFYKARVEELKEDNQVLLET--------KTMLEDQLEGTRA 372
Query: 151 E-EKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMEN 191
+KL ++ K+ LQLK +E++ + +++KI+ EN
Sbjct: 373 RSDKLHELEKENLQLKAKLHD--MEMERDMDRKKIEELMEEN 412
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 52.0 bits (123), Expect = 5e-07
Identities = 57/245 (23%), Positives = 108/245 (44%), Gaps = 35/245 (14%)
Query: 1 MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSM 60
+E Q +Q +E E R G Q+ E+R +LL R Q K+Q+LEY
Sbjct: 234 VERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEER-SLLAEQREQEKEQMLEYMEQ 292
Query: 61 VDASEEKTPEQIMQEK-QIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKK---NL 116
+ + K E+ Q+K +++A+I+ + +E ++ K ++ D+M + KK
Sbjct: 293 LQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREA 352
Query: 117 EKISRQSSVLMDNMKHLLELNKLIMKSQ--------------QESWDLE----------- 151
E + Q + + K + L + K+Q QE D E
Sbjct: 353 EFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARK 412
Query: 152 --EKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKIT 209
E ++RK RL+ + A + L +Q ++++ + + + ++R +I ++ L+ E K T
Sbjct: 413 KMETEAELRKSRLE-QVAFKEHALAVQVQRDRD--EFERILRAQREQIEKERLEEEKKAT 469
Query: 210 TVIQH 214
+QH
Sbjct: 470 GRLQH 474
Score = 42.4 bits (98), Expect = 4e-04
Identities = 37/155 (23%), Positives = 79/155 (50%), Gaps = 10/155 (6%)
Query: 58 KSMVDASEE----KTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALK 113
+S++ + EE K ++ +++EA+ + + E E A +K + + + +
Sbjct: 100 ESLIISPEEFERIKWASHVLTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEM---VW 156
Query: 114 KNLEKISRQSSVLMDNMKHLLE-LNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKL 172
N +K+S V + ++LL+ NKL M+ ++E D+ + +L+ + ++ Q E +
Sbjct: 157 NNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQ- 215
Query: 173 LEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIK 207
+IQ E + ++ LD M ER K I++ ++E K
Sbjct: 216 -QIQKELDTEEKRLDQMMEVERQKSIQRQEELERK 249
Score = 37.0 bits (84), Expect = 0.016
Identities = 35/162 (21%), Positives = 71/162 (43%), Gaps = 8/162 (4%)
Query: 50 TKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRM--R 107
T+++L +E T + +M K+I + E + N +++ E+ K + R
Sbjct: 120 TREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQR 179
Query: 108 LSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQ-QESWDLEEKLLDI-----RKKR 161
+ + E++ S ++++ H + +++ K Q Q+ D EEK LD R+K
Sbjct: 180 ANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKS 239
Query: 162 LQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQ 203
+Q ++ E K E + +Q ++ ER + Q Q
Sbjct: 240 IQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQ 281
Score = 31.2 bits (69), Expect = 0.87
Identities = 24/127 (18%), Positives = 64/127 (50%), Gaps = 10/127 (7%)
Query: 71 QIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNM 130
QI++++QI+ +++ E ++++ E+++ + + K+ E+I + ++
Sbjct: 210 QILEKQQIQKELDTEEKRLDQM---MEVERQKSIQRQEELERKRREERIRGRRQIVEQME 266
Query: 131 KHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQT-------EKNKQK 183
K+ E + L + +QE + E + ++++ L+ + + + L++Q E KQK
Sbjct: 267 KNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQK 326
Query: 184 IDLDSME 190
+L + E
Sbjct: 327 AELLAQE 333
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 48.9 bits (115), Expect = 4e-06
Identities = 41/184 (22%), Positives = 86/184 (46%), Gaps = 6/184 (3%)
Query: 21 RAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEA 80
R G Q A+ + L L Q ++++ + + EEK EQ ++ ++ E
Sbjct: 266 RLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE 325
Query: 81 KIEDLENEIEEVKVAFEIKKLALDRM-RLSTALKKNLEKISRQSSVLMDNMKHLLELNKL 139
K+ E ++ E + ++ D+M R +++ EKI Q + + + E ++
Sbjct: 326 KMWRQEEKMHEQEEKIREQE---DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEK 382
Query: 140 IMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIR 199
I + ++E W EEK+ + +KR + E K+ E Q EK +++ + + E+I+ +
Sbjct: 383 IQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE-QDEKIREQ-EEEMWRQEEKIRELE 440
Query: 200 QNLQ 203
+ +Q
Sbjct: 441 EMMQ 444
Score = 40.8 bits (94), Expect = 0.001
Identities = 32/155 (20%), Positives = 75/155 (48%), Gaps = 8/155 (5%)
Query: 51 KQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI--EEVKVAFEIKKLALDRMRL 108
++++ E + + E+K Q + ++ E KI + E ++ +E K+ + +K+ +
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 109 STALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQAS 168
+K E+ ++ + K + E ++ I + ++E W EEK+ ++ ++ Q
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE----EMMQDQ 446
Query: 169 ESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQ 203
E KL E+ E+ Q+ + E E+I+ + +Q
Sbjct: 447 EEKLREV--EEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Score = 40.4 bits (93), Expect = 0.001
Identities = 28/147 (19%), Positives = 73/147 (49%), Gaps = 2/147 (1%)
Query: 51 KQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI--EEVKVAFEIKKLALDRMRL 108
++++ E + + EEK Q + ++ + KI++ E E+ +E K+ + +K R
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 109 STALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQAS 168
+++ EKI Q + + + EL +++ +++ ++EEK+ + +K + ++
Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKI 471
Query: 169 ESKLLEIQTEKNKQKIDLDSMENSERI 195
+ + +IQ ++ K ++ E+I
Sbjct: 472 QRQEEKIQEQEEKTWRQEKLLKQEEKI 498
Score = 35.4 bits (80), Expect = 0.046
Identities = 36/169 (21%), Positives = 74/169 (43%), Gaps = 32/169 (18%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
E+++ L + +++L E + + EEK EQ E KI+ E +I+E +
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ-------EEKIQRQEEKIQEQE--- 482
Query: 97 EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLD 156
EK RQ +L K + E + + + +++ W+ EEK+ +
Sbjct: 483 --------------------EKTWRQEKLLKQEEK-IWEQEEKMWRQEEKMWEQEEKMQE 521
Query: 157 IRKK-RLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQM 204
+K + Q ++ E ++ Q E+ Q+ ++ E ER+ + Q ++
Sbjct: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Score = 33.1 bits (74), Expect = 0.23
Identities = 27/140 (19%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
Query: 57 YKSMVDASEEKTPEQIMQEKQ--IEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKK 114
Y++ + E K +QEK +E++ +++ ++++K E +L L + +L +
Sbjct: 207 YRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR 266
Query: 115 NLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLE 174
+++ S+ L ++ N L + +++ W EEK+ + +K + E K+ E
Sbjct: 267 LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE----QELKIRE 322
Query: 175 IQTEKNKQKIDLDSMENSER 194
+ + +Q+ + E R
Sbjct: 323 QEEKMWRQEEKMHEQEEKIR 342
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 48.9 bits (115), Expect = 4e-06
Identities = 41/184 (22%), Positives = 86/184 (46%), Gaps = 6/184 (3%)
Query: 21 RAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEA 80
R G Q A+ + L L Q ++++ + + EEK EQ ++ ++ E
Sbjct: 266 RLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE 325
Query: 81 KIEDLENEIEEVKVAFEIKKLALDRM-RLSTALKKNLEKISRQSSVLMDNMKHLLELNKL 139
K+ E ++ E + ++ D+M R +++ EKI Q + + + E ++
Sbjct: 326 KMWRQEEKMHEQEEKIREQE---DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEK 382
Query: 140 IMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIR 199
I + ++E W EEK+ + +KR + E K+ E Q EK +++ + + E+I+ +
Sbjct: 383 IQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE-QDEKIREQ-EEEMWRQEEKIRELE 440
Query: 200 QNLQ 203
+ +Q
Sbjct: 441 EMMQ 444
Score = 40.8 bits (94), Expect = 0.001
Identities = 32/155 (20%), Positives = 75/155 (48%), Gaps = 8/155 (5%)
Query: 51 KQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI--EEVKVAFEIKKLALDRMRL 108
++++ E + + E+K Q + ++ E KI + E ++ +E K+ + +K+ +
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 109 STALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQAS 168
+K E+ ++ + K + E ++ I + ++E W EEK+ ++ ++ Q
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE----EMMQDQ 446
Query: 169 ESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQ 203
E KL E+ E+ Q+ + E E+I+ + +Q
Sbjct: 447 EEKLREV--EEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Score = 40.4 bits (93), Expect = 0.001
Identities = 28/147 (19%), Positives = 73/147 (49%), Gaps = 2/147 (1%)
Query: 51 KQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI--EEVKVAFEIKKLALDRMRL 108
++++ E + + EEK Q + ++ + KI++ E E+ +E K+ + +K R
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 109 STALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQAS 168
+++ EKI Q + + + EL +++ +++ ++EEK+ + +K + ++
Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKI 471
Query: 169 ESKLLEIQTEKNKQKIDLDSMENSERI 195
+ + +IQ ++ K ++ E+I
Sbjct: 472 QRQEEKIQEQEEKTWRQEKLLKQEEKI 498
Score = 35.4 bits (80), Expect = 0.046
Identities = 36/169 (21%), Positives = 74/169 (43%), Gaps = 32/169 (18%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
E+++ L + +++L E + + EEK EQ E KI+ E +I+E +
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ-------EEKIQRQEEKIQEQE--- 482
Query: 97 EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLD 156
EK RQ +L K + E + + + +++ W+ EEK+ +
Sbjct: 483 --------------------EKTWRQEKLLKQEEK-IWEQEEKMWRQEEKMWEQEEKMQE 521
Query: 157 IRKK-RLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQM 204
+K + Q ++ E ++ Q E+ Q+ ++ E ER+ + Q ++
Sbjct: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Score = 33.1 bits (74), Expect = 0.23
Identities = 27/140 (19%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
Query: 57 YKSMVDASEEKTPEQIMQEKQ--IEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKK 114
Y++ + E K +QEK +E++ +++ ++++K E +L L + +L +
Sbjct: 207 YRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR 266
Query: 115 NLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLE 174
+++ S+ L ++ N L + +++ W EEK+ + +K + E K+ E
Sbjct: 267 LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE----QELKIRE 322
Query: 175 IQTEKNKQKIDLDSMENSER 194
+ + +Q+ + E R
Sbjct: 323 QEEKMWRQEEKMHEQEEKIR 342
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 48.9 bits (115), Expect = 4e-06
Identities = 45/212 (21%), Positives = 105/212 (49%), Gaps = 9/212 (4%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI---EEVK 93
E++M LL+ + + Q+ + ++ +EE+ + I + Q+EAK++++ + EE+
Sbjct: 876 EEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 935
Query: 94 VAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEK 153
KK L+ + LKK+++ + + ++ KH E NK + +E L+E
Sbjct: 936 AELTAKKRKLEDE--CSELKKDIDDL-ELTLAKVEKEKHATE-NK-VKNLTEEMAGLDEI 990
Query: 154 LLDIRKKRLQLKQASESKLLEIQTEKNK-QKIDLDSMENSERIKIIRQNLQMEIKITTVI 212
+ + K++ L++A + L ++Q E++K + ++ +++ + +L+ E K+ +
Sbjct: 991 IAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDL 1050
Query: 213 QHVFQNLILGSKVNWAEDPALKEIVLQLEKNV 244
+ + L K+ L+ LQLE+ +
Sbjct: 1051 ERAKRKLEGDLKLTQESIMDLENDKLQLEEKL 1082
Score = 44.3 bits (103), Expect = 1e-04
Identities = 47/187 (25%), Positives = 83/187 (44%), Gaps = 14/187 (7%)
Query: 45 RLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEV-----KVAFEIK 99
R R +Q+L+E V + I Q+K++E+ + L++E+EE + K
Sbjct: 1699 RSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAK 1758
Query: 100 KLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRK 159
K D ++ LKK + +S ++ MK +E + I Q + E+ L K
Sbjct: 1759 KAITDAAMMAEELKK-----EQDTSAHLERMKKNME--QTIKDLQHRLDEAEQIALKGGK 1811
Query: 160 KRLQLKQASESKLL-EIQTEKNKQKIDLDSMENSE-RIKIIRQNLQMEIKITTVIQHVFQ 217
K+LQ +A +L E++ E+ + + M SE RIK + + + K +Q +
Sbjct: 1812 KQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVD 1871
Query: 218 NLILGSK 224
L L K
Sbjct: 1872 KLQLKVK 1878
Score = 43.1 bits (100), Expect = 2e-04
Identities = 42/185 (22%), Positives = 88/185 (47%), Gaps = 26/185 (14%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIE-EVKVA 95
ED++ L + + + +QQ+ + + ++ QEK++ +E + ++E ++K+
Sbjct: 1016 EDKVNSLSKSKVKLEQQVDDLEGSLE-----------QEKKVRMDLERAKRKLEGDLKLT 1064
Query: 96 FE-IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
E I L D+++L LKK I++Q+S + D L+L K + ++Q +LEE+L
Sbjct: 1065 QESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEEL 1124
Query: 155 LDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQH 214
R R ++ EK + + + E SER++ ++I++ +
Sbjct: 1125 EAERTARAKV-------------EKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1171
Query: 215 VFQNL 219
FQ +
Sbjct: 1172 EFQKM 1176
Score = 34.3 bits (77), Expect = 0.10
Identities = 45/216 (20%), Positives = 97/216 (44%), Gaps = 43/216 (19%)
Query: 43 LLRLRAQTKQQLLEYKSMVDASEEKTPEQI-------MQEKQIEAKIE-DLENEIEEVKV 94
L ++R Q + + LE +S ++ +E + ++ QI+A+IE L + EE++
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
Query: 95 AFEIKKLALDRMRLST-----------ALKKNLE--------KISRQSSVLMDNMKHLLE 135
A + +D ++ S +KK +E ++S + + + K +
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1647
Query: 136 LNKLIMKSQ-------QESWDLEEKLLDI-RKKRLQLKQASESKLLEIQTEKNKQKIDLD 187
L L+ +Q + + DL+E + + R+ L + E + + QTE++++ + +
Sbjct: 1648 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQE 1707
Query: 188 SMENSERIK--------IIRQNLQMEIKITTVIQHV 215
+E SER++ +I Q +ME +T + V
Sbjct: 1708 LIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEV 1743
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 48.9 bits (115), Expect = 4e-06
Identities = 46/201 (22%), Positives = 93/201 (46%), Gaps = 17/201 (8%)
Query: 43 LLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLA 102
+L +RA+ +++L E EE+ QI +EK ++E L+ +EE++ ++ +
Sbjct: 462 VLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQA--QVHSMD 519
Query: 103 LDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRL 162
+ LK+ E + +Q + +K E + +K + EE+L D+R +
Sbjct: 520 GAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGK------EEELQDVRDQLE 573
Query: 163 QLKQASESKLLEIQTEKNKQKIDLDSM-----ENSERIKIIRQNLQMEIKITTVIQHVFQ 217
Q ++ + L I + K + K +D + S +K +++ L +E K +Q Q
Sbjct: 574 QAQEERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQ 633
Query: 218 NLILGSKVNWAEDPALKEIVL 238
+++ SK L+E+VL
Sbjct: 634 DILTNSK----SRSGLEELVL 650
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 47.0 bits (110), Expect = 2e-05
Identities = 52/244 (21%), Positives = 104/244 (42%), Gaps = 39/244 (15%)
Query: 43 LLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFE-IKKL 101
LL L Q +++++ Y S+ + E E + + ++I + ++ E E++ +AFE KK+
Sbjct: 699 LLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKI 758
Query: 102 ALDR--------MRLSTALKKNLEKISRQSSV-------LMDNMKHLLELNKLIMKSQQE 146
L++ RL L+K ++ Q ++ HL L++L+ +S+ E
Sbjct: 759 HLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGE 818
Query: 147 ---------------SWDLEEKLLDIRKKRLQLKQASESKLLEI-QTEKNKQKIDLDSME 190
+ E+ + +R+ L+ E +L + Q E NK+K + +
Sbjct: 819 MKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKK 878
Query: 191 NSERI-------KIIRQNLQMEIKITTVIQHVFQNLILGSKVNWAEDPALKEIVLQLEKN 243
SE + KI +LQ + ++QH Q + + L++ +LEK
Sbjct: 879 KSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQ 938
Query: 244 VDMM 247
V +
Sbjct: 939 VSKL 942
Score = 38.5 bits (88), Expect = 0.005
Identities = 39/180 (21%), Positives = 84/180 (46%), Gaps = 23/180 (12%)
Query: 36 SEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVA 95
+E+++ ++ + +Q L E K + EQ Q K+ E + + EE+ A
Sbjct: 310 AENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKA 369
Query: 96 FEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLL 155
F+ K + + LEK+ + +L N+ + + NK + QE L + L
Sbjct: 370 FQQYK---------KKVAEKLEKVQAEEEILERNLTNCEKENKRL----QERCGLYKSEL 416
Query: 156 DIRKKRL-QLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQH 214
+I K++L QLK+ + K+K+ + +++NSE + + ++ Q +K+ + +++
Sbjct: 417 EILKEKLRQLKE---------ENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELEN 467
Score = 33.5 bits (75), Expect = 0.18
Identities = 32/173 (18%), Positives = 81/173 (46%), Gaps = 5/173 (2%)
Query: 44 LRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLAL 103
L+++ + Q+ E ++ + ++ + + QE ++ED + ++E+ E ++L
Sbjct: 890 LKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLE-QELQK 948
Query: 104 DRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQ 163
R + L+K EK + + ++EL + + E +E+L + K+ +
Sbjct: 949 QRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMH 1008
Query: 164 LKQASESK---LLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQ 213
LK+ E+K L ++ ++ K +L+ N+ + ++ + E ++T +Q
Sbjct: 1009 LKRDGENKAMHLSQLDMILDQTKTELEKKTNAVK-ELEKLQHSTETELTEALQ 1060
Score = 31.2 bits (69), Expect = 0.87
Identities = 34/173 (19%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 35 CSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKV 94
C + + L RL ++K ++ + D + + Q+ +E K+ L++ +E K
Sbjct: 800 CKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEET---IKVRQLDSALEICK- 855
Query: 95 AFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
++L L +L +K +++ ++S + K L N + ++ +++ L+ L
Sbjct: 856 ----EELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTL 911
Query: 155 LDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIK 207
+++ LQ + +L + QT+ KQ L+ +R + +ME K
Sbjct: 912 QQ-QQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEK 963
Score = 29.3 bits (64), Expect = 3.3
Identities = 26/136 (19%), Positives = 60/136 (44%), Gaps = 17/136 (12%)
Query: 52 QQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVK------------VAFEIK 99
Q+L + V S + E Q+ Q + +IE L +E+E++K +A E+
Sbjct: 1253 QELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELG 1312
Query: 100 KLALDRMRLSTALKKNLEKISRQSSVL-----MDNMKHLLELNKLIMKSQQESWDLEEKL 154
+ L ++ ++K+S + L M+ + H K + + + +++
Sbjct: 1313 ASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLN 1372
Query: 155 LDIRKKRLQLKQASES 170
+ K +L+L++A ++
Sbjct: 1373 EQLEKAKLELEEAQDT 1388
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 46.2 bits (108), Expect = 3e-05
Identities = 39/166 (23%), Positives = 76/166 (45%), Gaps = 11/166 (6%)
Query: 42 LLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEV-KVAFEIKK 100
LLL Q + ++ Y+ + + EE Q ++ +++ E+L N ++ ++ E+KK
Sbjct: 2713 LLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKK 2772
Query: 101 LALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEK-----LL 155
+D ++ LKK E+ + +L+ + K L E +++ K + +EK ++
Sbjct: 2773 TKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVM 2832
Query: 156 DIRKKRL-----QLKQASESKLLEIQTEKNKQKIDLDSMENSERIK 196
D + L +LK+ E K E +K L S E E+ K
Sbjct: 2833 DTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAK 2878
Score = 38.1 bits (87), Expect = 0.007
Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 44/201 (21%)
Query: 36 SEDRMTLLLRLRAQTK---QQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEV 92
SE + + L A+ K Q L + ++ + + K Q + ++ KI EN
Sbjct: 495 SEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQEN----- 549
Query: 93 KVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLE-LNKLIMKSQQESWDLE 151
L L++++L+ A +LEK S L+ +H +E LN + K+++ES L
Sbjct: 550 -------SLTLEKLKLAVA---DLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALL 599
Query: 152 EKLLDIRKKRLQLKQ--------ASESKLLEIQTEKNKQKI--------------DLDSM 189
L +K+ +LK+ SE++ L Q E K+ + + S
Sbjct: 600 SALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSH 659
Query: 190 ENSERIKII---RQNLQMEIK 207
E +ER++ + R+NL +EI+
Sbjct: 660 EYNERVRTLEMDRENLSVEIR 680
Score = 37.4 bits (85), Expect = 0.012
Identities = 42/182 (23%), Positives = 84/182 (46%), Gaps = 27/182 (14%)
Query: 30 GAQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI 89
G Q +D L+ + Q ++QL+ S V+ Q+ +E+ +E + +L E+
Sbjct: 2513 GKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEH-----QLWKEQNLE--LRNLTVEL 2565
Query: 90 EEVKVAFEIKKLAL-DRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKS---QQ 145
E+ + K +L D + + + KNLE + MD M + ++NK+ K Q+
Sbjct: 2566 EQKIQVLQSKNASLQDTLEVLQSSYKNLE--NELELTKMDKMSFVEKVNKMTAKETELQR 2623
Query: 146 ESWDLEEKLLDIRKK----------RLQLK----QASESKLLEIQTEKNKQKIDLDSMEN 191
E ++ +K +++++ LQL ++S+ +L E+ E ++ K LD M
Sbjct: 2624 EMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHK 2683
Query: 192 SE 193
+
Sbjct: 2684 DQ 2685
Score = 35.8 bits (81), Expect = 0.035
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 51 KQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLST 110
K ++ + + SEE I+ + +A++E L+ +IEE+ + ++ +L L +R
Sbjct: 2153 KDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR--- 2209
Query: 111 ALKKNLEKISRQSSVLMDNMKHLLELNKLIM--KSQQESWDLEEKLLDIRKKRLQLKQAS 168
+ K+NL K ++ + + LL K ++ K Q E EE + + QLK+ +
Sbjct: 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2269
Query: 169 ES 170
E+
Sbjct: 2270 EA 2271
Score = 33.1 bits (74), Expect = 0.23
Identities = 32/164 (19%), Positives = 79/164 (48%), Gaps = 14/164 (8%)
Query: 44 LRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLAL 103
++++A+ Q+L + K+M + + + + ++Q+E +E+ + ++ + AF+ ++
Sbjct: 415 IQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKE 474
Query: 104 DRMRLS-TALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRL 162
+ +R S +KK + S + HL K I + +S + E+ +
Sbjct: 475 NELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEE--------M 526
Query: 163 QLKQAS-ESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQME 205
+ K S E+ L ++Q + N+Q+ L E++K+ +L+ +
Sbjct: 527 KAKNTSQETMLRDLQEKINQQENSL----TLEKLKLAVADLEKQ 566
Score = 32.0 bits (71), Expect = 0.51
Identities = 25/116 (21%), Positives = 64/116 (55%), Gaps = 7/116 (6%)
Query: 81 KIEDLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSV---LMDNMKHLLELN 137
KI++LE +++++K + ++ LD L AL+K +K+ + + L + L+E+
Sbjct: 19 KIQELEGQLDKLKKEKQQRQFQLD--SLEAALQKQKQKVENEKTEGTNLKRENQRLMEIC 76
Query: 138 KLIMKSQQE-SWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENS 192
+ + K++Q+ S +L+ K + + QL + + ++ +++ E + K +L+ + +
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQL-NSGKKQIEKLEQELKRCKSELERSQQA 131
Score = 30.4 bits (67), Expect = 1.5
Identities = 16/44 (36%), Positives = 26/44 (59%)
Query: 147 SWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSME 190
SW LEE + + LQ Q E +L +++ EK +++ LDS+E
Sbjct: 2 SWALEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLE 45
Score = 30.4 bits (67), Expect = 1.5
Identities = 35/180 (19%), Positives = 85/180 (47%), Gaps = 12/180 (6%)
Query: 42 LLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKL 101
+LL+ +T + A++EK + + + E+ +NE+E++K AF K+
Sbjct: 1024 ILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAF-AKEH 1082
Query: 102 ALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQ-----QESWDLEEKLLD 156
+L+ A ++N + + + + ++ + N+ KS+ QE L+E+
Sbjct: 1083 QEFLTKLAFAEERN-QNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNK 1141
Query: 157 IRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNL-----QMEIKITTV 211
++K+ L Q +E + ++T+ Q ++ + + NS + + +N QM++++ +
Sbjct: 1142 MQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEI 1201
Score = 29.3 bits (64), Expect = 3.3
Identities = 35/148 (23%), Positives = 65/148 (43%), Gaps = 6/148 (4%)
Query: 70 EQIMQEKQIEAK---IEDLENEIEEVKVAFEIKKLALDRM-RLSTALKKNLEKISRQSSV 125
E++ EK E K I LE E+ V + LD M + +TAL + EK+ ++
Sbjct: 1931 EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQE 1990
Query: 126 LMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKID 185
L + L ++ +E +L + L + L+ K + KL + EK+ Q +
Sbjct: 1991 LESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSL--EKDSQALS 2048
Query: 186 LDSMENSERIKIIRQNLQMEIKITTVIQ 213
L E +I + + ++ +K + +Q
Sbjct: 2049 LTKCELENQIAQLNKEKELLVKESESLQ 2076
Score = 27.7 bits (60), Expect = 9.6
Identities = 15/47 (31%), Positives = 27/47 (57%)
Query: 108 LSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
L +K+ K+ Q LM ++ +EL K++ + ++E+ DL EKL
Sbjct: 1800 LLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKL 1846
Score = 27.7 bits (60), Expect = 9.6
Identities = 27/156 (17%), Positives = 70/156 (44%), Gaps = 13/156 (8%)
Query: 44 LRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDL------ENEIEEVKVAFE 97
L+ + Q+ ++ + S+ E Q+ +EK++ K + E++ E++ V+
Sbjct: 2033 LQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKA 2092
Query: 98 IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDI 157
++ +++ + L E++ + + + +L I +++ + EKL +
Sbjct: 2093 LEAALVEKGEFALRLSSTQEEVHQLR-------RGIEKLRVRIEADEKKQLHIAEKLKER 2145
Query: 158 RKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSE 193
++ LK E+ E+Q + Q++ + ENS+
Sbjct: 2146 ERENDSLKDKVENLERELQMSEENQELVILDAENSK 2181
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 46.2 bits (108), Expect = 3e-05
Identities = 46/182 (25%), Positives = 88/182 (48%), Gaps = 21/182 (11%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDL---ENEIEEVK 93
E++M LL+ + + Q+ + +EE+ + I + Q+EAKI+++ E EE+
Sbjct: 877 EEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEIN 936
Query: 94 VAFEIKKLALDRMRLSTALKKNLE-------KISRQSSVLMDNMKHLLE----LNKLIMK 142
KK L+ + LKK+++ K+ ++ + +K+L E L++ I K
Sbjct: 937 AELTAKKRKLEDE--CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 994
Query: 143 SQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENS-ERIKIIRQN 201
+E L+E ++ L QA E K+ + K K + +D +E S E+ K +R +
Sbjct: 995 LSKEKKALQE----THQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMD 1050
Query: 202 LQ 203
L+
Sbjct: 1051 LE 1052
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/182 (23%), Positives = 86/182 (47%), Gaps = 22/182 (12%)
Query: 45 RLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEV-----KVAFEIK 99
R R +Q+LL+ V + I +K++E + L++E+EEV + K
Sbjct: 1700 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAK 1759
Query: 100 KLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRK 159
K D ++ LKK + +S ++ MK LE + + Q + E+ L K
Sbjct: 1760 KAITDAAMMAEELKK-----EQDTSAHLERMKKNLE--QTVKDLQHRLDEAEQLALKGGK 1812
Query: 160 KRLQLKQASESKLLEIQTE-KNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHVFQN 218
K++ Q E+++ E++ E +N+QK N+E +K +R++ + ++T + +N
Sbjct: 1813 KQI---QKLEARVRELEGEVENEQK------RNAEAVKGLRKHERRVKELTYQTEEDRKN 1863
Query: 219 LI 220
++
Sbjct: 1864 VL 1865
Score = 37.4 bits (85), Expect = 0.012
Identities = 39/173 (22%), Positives = 82/173 (47%), Gaps = 15/173 (8%)
Query: 45 RLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQI---EAKIEDLENEIEEVKVA-FEIKK 100
+L + +++ E +++ E++ +I +K+I +A+IE+L EIE + + + +K
Sbjct: 1078 QLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEK 1137
Query: 101 LALDRMRLSTALKKNLEKISRQSSVLMD-NMKHLLELNKLIMKSQQESWDLEEKLLDIRK 159
D R + + LE+ +S ++ N K E KL ++ + E + +RK
Sbjct: 1138 QRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK 1197
Query: 160 KRL--------QLKQASESKLLEIQTEKNKQKIDLDSM-ENSERIKIIRQNLQ 203
K Q+ K +++ EK++ K++ D + N+E I + NL+
Sbjct: 1198 KHADSMAELGEQIDNLQRVK-QKLEKEKSELKMETDDLSSNAEAISKAKGNLE 1249
Score = 34.7 bits (78), Expect = 0.079
Identities = 30/172 (17%), Positives = 81/172 (47%), Gaps = 6/172 (3%)
Query: 36 SEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVA 95
S D++ L R +Q++ + + ++ E +KQ+E + +++ +EE + +
Sbjct: 1494 SLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEAS 1553
Query: 96 FEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLL 155
E ++ + +R+ L + ++ R+ + + + L + ++++ Q + D E +
Sbjct: 1554 LEHEEGKI--LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAE---I 1608
Query: 156 DIRKKRLQLKQASESKLLEIQTEKN-KQKIDLDSMENSERIKIIRQNLQMEI 206
R L++K+ E L E++ + N ++ +S+ N + I + Q+ +
Sbjct: 1609 RSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHL 1660
Score = 32.7 bits (73), Expect = 0.30
Identities = 34/141 (24%), Positives = 73/141 (51%), Gaps = 16/141 (11%)
Query: 106 MRLSTALKKNLEKISRQSSVLMDNMKHLLELNK-LIMKSQQESWDLEEKLLDIRKKRLQL 164
M+L +K L+ S ++ M MK + K + KS+ + +LEEK++ + K++ L
Sbjct: 833 MKLFFKIKPLLK--SAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDL 890
Query: 165 KQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHVFQNLILGSK 224
+ L++Q+E + D+ E E ++I+ +Q+E KI V + + + ++
Sbjct: 891 Q-------LQVQSEADSL---ADAEERCE--QLIKNKIQLEAKIKEVTERAEEEEEINAE 938
Query: 225 VNWAEDPALKEIVLQLEKNVD 245
+ A+ L++ +L+K++D
Sbjct: 939 LT-AKKRKLEDECSELKKDID 958
Score = 27.7 bits (60), Expect = 9.6
Identities = 29/145 (20%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Query: 47 RAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRM 106
RA+ + + EY +D + + ++ +IE+L++++EE A AL
Sbjct: 1280 RARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSS 1339
Query: 107 RLSTALKKNLEKISRQSSVLMDN--MKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQL 164
R L + + ++ + K E+ + K + ++ E+L + +KK Q
Sbjct: 1340 RHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1399
Query: 165 KQASESKLLEIQT-----EKNKQKI 184
Q +E + + EK KQ++
Sbjct: 1400 LQEAEEHVEAVNAKCASLEKTKQRL 1424
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 45.8 bits (107), Expect = 3e-05
Identities = 48/212 (22%), Positives = 97/212 (45%), Gaps = 29/212 (13%)
Query: 44 LRLRAQTKQQLLE-----YKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEI 98
LR R K+Q LE ++ V+ EE+ ++K+++ I++LE ++EE + A +
Sbjct: 902 LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ- 960
Query: 99 KKLALDRMRLSTALKKNLE----------KISRQSSVLMDNMKHLL-----------ELN 137
KL L+++ LKK E K++++ +L D + L
Sbjct: 961 -KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA 1019
Query: 138 KLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKI 197
KL K + DLEE+L K+R +L++ + KL T+ + Q +L + ++++
Sbjct: 1020 KLKNKHEAMITDLEERLRREEKQRQELEK-TRRKLEGDSTDLSDQIAELQAQIAELKMQL 1078
Query: 198 IRQNLQMEIKITTVIQHVFQNLILGSKVNWAE 229
++ +++ + V + Q + K+ E
Sbjct: 1079 AKKEEELQAALARVEEEAAQKNMALKKIRELE 1110
Score = 40.8 bits (94), Expect = 0.001
Identities = 47/201 (23%), Positives = 84/201 (41%), Gaps = 24/201 (11%)
Query: 34 ACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVK 93
A + ++ L + L+A Q + + + SEEK + + Q +++EA++ED E + +
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELED-ERKQRSMA 1608
Query: 94 VAFEIKKLALDRMRLST---ALKKNLEKISRQSSVLMDNMKHLL---------------- 134
VA KKL +D L + KN ++ +Q L MK +
Sbjct: 1609 VAAR-KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQ 1667
Query: 135 --ELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENS 192
E K + + E L+E+L + + Q +Q + EI K + L+
Sbjct: 1668 AKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRL 1727
Query: 193 E-RIKIIRQNLQMEIKITTVI 212
E RI + + L+ E T +I
Sbjct: 1728 EARIAQLEEELEEEQGNTELI 1748
Score = 37.7 bits (86), Expect = 0.009
Identities = 38/182 (20%), Positives = 81/182 (44%), Gaps = 7/182 (3%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI-EEVKVA 95
ED+ L + + + ++ E+ + + EEK+ + + EA I DLE + E K
Sbjct: 984 EDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1043
Query: 96 FEIKKLALDRMRLSTALKKNLEKISRQSSVL-MDNMKHLLELNKLIMKSQQESWDLEEKL 154
E++K ST L + ++ Q + L M K EL + + ++E+ L
Sbjct: 1044 QELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL 1103
Query: 155 LDIRKKRLQLKQASESKLLEIQTEK-NKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQ 213
IR+ Q+ + E ++++E+ ++ K + + E ++ ++ L+ + T Q
Sbjct: 1104 KKIRELESQISELQE----DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 214 HV 215
+
Sbjct: 1160 EL 1161
Score = 34.7 bits (78), Expect = 0.079
Identities = 38/189 (20%), Positives = 89/189 (47%), Gaps = 28/189 (14%)
Query: 36 SEDRMTLLLRLRAQTKQQLLEYKSMVDA-------SEEKTPEQIMQEKQIEAKIEDLENE 88
+E+R+T + L++Q + L+ + + A +EE +++++E DLE
Sbjct: 864 AENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEAR 923
Query: 89 IEEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESW 148
+EE + + L ++ ++ +++ E++ + S + L+L K+ +++ +
Sbjct: 924 VEEEEE--RCQHLQAEKKKMQQNIQELEEQLEEEESA-----RQKLQLEKVTTEAKLKKL 976
Query: 149 DLEEKLLDIRKKRLQLKQASESKLLEIQ--------TEKNKQKIDLDSMENSERIKI--I 198
+ E+ +L+ + +L A E KLLE + TE+ ++ L ++N I +
Sbjct: 977 EEEQIILEDQNCKL----AKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDL 1032
Query: 199 RQNLQMEIK 207
+ L+ E K
Sbjct: 1033 EERLRREEK 1041
Score = 31.2 bits (69), Expect = 0.87
Identities = 34/159 (21%), Positives = 69/159 (43%), Gaps = 10/159 (6%)
Query: 38 DRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFE 97
D +T LL +L + S +++ + T E + +E + + + ++E+ K +F
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 98 IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDI 157
+++ K NLEK + +MK +E + +++ +E +K L+
Sbjct: 1343 ------EQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEG 1396
Query: 158 RKKRLQLKQASESKL----LEIQTEKNKQKIDLDSMENS 192
+R + K A+ KL +Q E + +DLD S
Sbjct: 1397 LSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 1435
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 45.8 bits (107), Expect = 3e-05
Identities = 44/180 (24%), Positives = 87/180 (48%), Gaps = 17/180 (9%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI---EEVK 93
E++M LL+ + + Q+ + + +EE+ + I + Q+EAK++++ + EE+
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 94 VAFEIKKLAL-----DRMRLSTALKKNLEKISRQSSVLMDNMKHLLE----LNKLIMKSQ 144
KK L + R L+ L K+ ++ + +K+L E L+++I K
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 145 QESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENS-ERIKIIRQNLQ 203
+E L+E ++ L QA E K+ + K K + +D +E S E+ K +R +L+
Sbjct: 994 KEKKALQE----AHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLE 1049
Score = 44.3 bits (103), Expect = 1e-04
Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 14/187 (7%)
Query: 45 RLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEV-----KVAFEIK 99
R R +Q+L+E V + I Q+K+++A + L+ E+EE + K
Sbjct: 1697 RSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAK 1756
Query: 100 KLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRK 159
K D ++ LKK + +S ++ MK +E + I Q + E+ L K
Sbjct: 1757 KAITDAAMMAEELKK-----EQDTSAHLERMKKNME--QTIKDLQHRLDEAEQIALKGGK 1809
Query: 160 KRLQLKQASESKL-LEIQTEKNKQKIDLDSMENSE-RIKIIRQNLQMEIKITTVIQHVFQ 217
K+LQ +A +L E++ E+ + + M SE RIK + + + K +Q +
Sbjct: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869
Query: 218 NLILGSK 224
L L K
Sbjct: 1870 KLQLKVK 1876
Score = 33.9 bits (76), Expect = 0.13
Identities = 38/185 (20%), Positives = 84/185 (45%), Gaps = 26/185 (14%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIE-EVKVA 95
ED++ L + + + +QQ+ + + ++ QEK++ +E + ++E ++K+
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLEGSLE-----------QEKKVRMDLERAKRKLEGDLKLT 1062
Query: 96 FE-IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
E I L D+ +L LKK +++ ++ + D +L K + + Q +LEE+L
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 155 LDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQH 214
R R ++ EK + + + E SER++ ++I++ +
Sbjct: 1123 EAERTARAKV-------------EKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1169
Query: 215 VFQNL 219
FQ +
Sbjct: 1170 EFQKM 1174
Score = 33.1 bits (74), Expect = 0.23
Identities = 49/223 (21%), Positives = 98/223 (43%), Gaps = 30/223 (13%)
Query: 36 SEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVA 95
S + + R ++++ + + +S + E KQ+EA+ +L++ +EE + +
Sbjct: 1491 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEAS 1550
Query: 96 FEIKKLALDRMRLS-TALKKNLEKISRQSSVLMDNMKHLLELNKL-IMKSQQESWDLEEK 153
E ++ + R +L +K +E+ + M+ K N L ++ S Q S D E +
Sbjct: 1551 LEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR----NHLRVVDSLQTSLDAETR 1606
Query: 154 LLDIRKKRLQLKQASESKLLEIQ----------TEKNKQKIDLDSMENSERIKI---IRQ 200
R + L++K+ E L E++ E KQ L S+ +I++ +R
Sbjct: 1607 ---SRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 201 NLQMEIKITTVIQHVFQNLILGSKVNWAEDPALKEIVLQLEKN 243
N ++ I V + NL+ AE L+ +V Q E++
Sbjct: 1664 NDDLKENIAIVERR--NNLL------QAELEELRAVVEQTERS 1698
Score = 32.3 bits (72), Expect = 0.39
Identities = 36/168 (21%), Positives = 72/168 (42%), Gaps = 31/168 (18%)
Query: 46 LRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDR 105
L +Q +++L E ++ ++ EE+ + ++E DL E+EE+
Sbjct: 1100 LGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI------------- 1146
Query: 106 MRLSTALKKNLEKISRQSSVLMD-NMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRL-- 162
+ LE+ +SV ++ N K E K+ ++ + E +RKK
Sbjct: 1147 -------SERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 163 ------QLKQASESKLLEIQTEKNKQKIDLDSM-ENSERIKIIRQNLQ 203
Q+ K +++ EK++ K++LD + N E+I + NL+
Sbjct: 1200 VAELGEQIDNLQRVK-QKLEKEKSEFKLELDDVTSNMEQIIKAKANLE 1246
Score = 32.3 bits (72), Expect = 0.39
Identities = 33/166 (19%), Positives = 77/166 (46%), Gaps = 21/166 (12%)
Query: 46 LRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIED-----LENEIEEVKVAFEIKK 100
LRAQ + + K+ ++ + E++ Q K+ ++ D L+ E A +KK
Sbjct: 1559 LRAQL--EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKK 1616
Query: 101 LALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQ-------QESWDLEEK 153
++ L + ++S + + + K + L L+ +Q + + DL+E
Sbjct: 1617 ------KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKEN 1670
Query: 154 LLDI-RKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKII 198
+ + R+ L + E + + QTE++++ + + +E SER++++
Sbjct: 1671 IAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLL 1716
Score = 28.9 bits (63), Expect = 4.3
Identities = 49/222 (22%), Positives = 96/222 (43%), Gaps = 32/222 (14%)
Query: 42 LLLRLRAQTKQQL--LEYKSMVDASEEKTPEQ-----IMQEK-----QIEAKIEDLENEI 89
++ R++AQ++ L +EYK +++ + Q M K ++ KI+ L
Sbjct: 784 IITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSA 843
Query: 90 EEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWD 149
E K E+ + + RL AL+K+ + ++ ++ +L + Q D
Sbjct: 844 EREK---EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 150 LEEKLLDIRKKRLQL--KQASESKLLEIQTEKN------KQKIDLDSMENSERIKIIRQN 201
EE+ + K ++QL K ++ LE + E N K+K++ + E I +
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI----DD 956
Query: 202 LQMEIKITTVIQHVFQNLILGSKVNWAEDPA-LKEIVLQLEK 242
L++ + +H +N + N E+ A L EI+ +L K
Sbjct: 957 LELTLAKVEKEKHATENKV----KNLTEEMAGLDEIIAKLTK 994
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 45.8 bits (107), Expect = 3e-05
Identities = 39/153 (25%), Positives = 72/153 (47%), Gaps = 17/153 (11%)
Query: 54 LLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALK 113
L E+K +D S+ + + + + ++ + N EEV +D++
Sbjct: 1457 LAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEV----------VDQLETLRREN 1506
Query: 114 KNL-EKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKL 172
KNL E+IS + + + K+L E K +QE DL+ L ++ + ESK+
Sbjct: 1507 KNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGS----LEHEESKI 1562
Query: 173 LEIQTEKNKQKIDLDS--MENSERIKIIRQNLQ 203
L +Q E ++ K +LD +E E I+ +++N Q
Sbjct: 1563 LRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQ 1595
Score = 44.7 bits (104), Expect = 8e-05
Identities = 42/174 (24%), Positives = 86/174 (49%), Gaps = 22/174 (12%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIE-EVKVA 95
ED++ L+++ A+ +QQ + + ++ QEK++ A +E + ++E ++K++
Sbjct: 1018 EDKVNGLIKINAKLEQQTDDLEGSLE-----------QEKKLRADLERAKRKLEGDLKMS 1066
Query: 96 FE-IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
E I L D+ ++ LKK ++S+ + + D H L+ K I + Q +LEE++
Sbjct: 1067 QESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEI 1126
Query: 155 -------LDIRKKRLQLKQASE--SKLLEIQTEKNKQKIDLDSMENSERIKIIR 199
I K+R L + E S+ LE + +I+++ +E K+ R
Sbjct: 1127 EAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRR 1180
Score = 40.0 bits (92), Expect = 0.002
Identities = 39/149 (26%), Positives = 80/149 (53%), Gaps = 10/149 (6%)
Query: 37 EDRMTLLLRLRAQTKQQLL-EYKSMVDASEEKTPEQIMQEKQIEAKIEDLE---NEIEEV 92
E++M LL+ + + Q+ E ++++DA EE+ I + +EAK+++L E EE+
Sbjct: 878 EEKMVSLLQEKNDLQLQVQSETENLMDA-EERCEGLIKSKILLEAKVKELTERLEEEEEM 936
Query: 93 KVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEE 152
KK L+ ++LK++++ + + ++ KH E NK + +E LEE
Sbjct: 937 NSELVAKKRNLEDK--CSSLKRDIDDL-ELTLTKVEKEKHATE-NK-VKNLSEEMTALEE 991
Query: 153 KLLDIRKKRLQLKQASESKLLEIQTEKNK 181
+ + K++ L++A + L ++Q E++K
Sbjct: 992 NISKLTKEKKSLQEAHQQTLDDLQVEEDK 1020
Score = 38.5 bits (88), Expect = 0.005
Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 20/157 (12%)
Query: 45 RLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKI----EDLENEIEEVKVAFE-IK 99
R R ++Q+LL+ V + I +K++EA I ++EN I+E + A E K
Sbjct: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760
Query: 100 KLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRK 159
K D ++ LKK + +S ++ MK LE + + Q + E+ L K
Sbjct: 1761 KAITDAAMMAEELKK-----EQDTSAHLERMKKNLE--QTVKDLQHRLDEAEQLALKGGK 1813
Query: 160 KRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIK 196
K++ Q E+++ E++ E +D++ +E +K
Sbjct: 1814 KQI---QKLENRVRELENE-----LDVEQKRGAEALK 1842
Score = 37.4 bits (85), Expect = 0.012
Identities = 39/179 (21%), Positives = 89/179 (49%), Gaps = 14/179 (7%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
E+ ++ L + + ++ + + E+K I ++E + +DLE +E+
Sbjct: 990 EENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQE---- 1045
Query: 97 EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLD 156
KKL D R L+ +L K+S++S + ++N K +E + + K + E L+ K+ D
Sbjct: 1046 --KKLRADLERAKRKLEGDL-KMSQESIMDLENDKQQIE--EKLKKKEFELSQLQAKIDD 1100
Query: 157 IRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHV 215
+ LQ ++ + K L+ + E+ +++I+ E++ R KI +Q + ++ + + +
Sbjct: 1101 EQVHSLQFQK--KIKELQARIEELEEEIE---AEHTLRAKIEKQRSDLARELEEISERL 1154
Score = 36.2 bits (82), Expect = 0.027
Identities = 36/159 (22%), Positives = 75/159 (47%), Gaps = 19/159 (11%)
Query: 53 QLLEYKSMVDASEEKTPEQIMQEKQ-----IEAKIEDLENEIEEVKVAFEIKKLALDRMR 107
+L + KS +D + E+I Q K+ EA L+ EI A +KK +
Sbjct: 1568 ELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKK------K 1621
Query: 108 LSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQ-------QESWDLEEKLLDI-RK 159
+ L + ++ + + + KHL + + SQ + + DL+E+L + R+
Sbjct: 1622 MEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERR 1681
Query: 160 KRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKII 198
L L++ E K+ QTE+ ++ + + ++ S+R++++
Sbjct: 1682 NGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLL 1720
Score = 32.0 bits (71), Expect = 0.51
Identities = 33/179 (18%), Positives = 89/179 (49%), Gaps = 23/179 (12%)
Query: 38 DRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFE 97
D++ L R ++++ + + + + E +K +E + DL+ +EEV+ + E
Sbjct: 1497 DQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLE 1556
Query: 98 IKKLALDRMRLSTALKKN------------LEKISRQSSVLMDNMKHLLELNKLIMKSQQ 145
++ + R++L + K+ +E++ R S + ++ +L+ ++S+
Sbjct: 1557 HEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAE---IRSRN 1613
Query: 146 ESWDLEEKLL-DIRKKRLQL----KQASESK--LLEIQTEKNKQKIDL-DSMENSERIK 196
++ L++K+ D+ + +QL +Q +E++ L +Q + ++ L D++ ++E +K
Sbjct: 1614 DALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLK 1672
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 45.8 bits (107), Expect = 3e-05
Identities = 51/239 (21%), Positives = 103/239 (43%), Gaps = 29/239 (12%)
Query: 31 AQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASE----EKTPEQIMQEKQIEAKIEDLE 86
A ++DR+ L + QL E K V + KT + E A+ DL+
Sbjct: 607 AHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQ 666
Query: 87 NEIEEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQE 146
N ++ + A + K+ L++ ++T L + K+ + HL E + + +Q+
Sbjct: 667 NHLDTAQNALQDKQQELNK--ITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQK 724
Query: 147 SWDLEEKLLDIRKKRLQLKQASESKLLEIQ-------------TEKNKQ---------KI 184
+ +LE ++ + L++K + E L ++Q TE +KQ
Sbjct: 725 TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSST 784
Query: 185 DLDSMENSERIKIIRQNLQMEIKITTVIQHVFQNLILGSKVNWAE-DPALKEIVLQLEK 242
LD + SE ++ I+Q L + + +++ F+ L +K+ E + ++ V +L+K
Sbjct: 785 RLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQK 843
Score = 41.6 bits (96), Expect = 6e-04
Identities = 57/212 (26%), Positives = 98/212 (46%), Gaps = 25/212 (11%)
Query: 45 RLRAQTKQQLLE-YKSMVDASEEKTP------EQIMQEKQIEAKIEDLENEIEEVKVAFE 97
RL Q K + LE K + EE+ E + QE +I+ E+L N I+ E
Sbjct: 785 RLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQH--EELNNRIQTTVT--E 840
Query: 98 IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDI 157
++K+ +++ L T L +K+S+ S L ++ E K K + DLE+ ++
Sbjct: 841 LQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKS---EFEKENQKGKAAILDLEKTCKEL 897
Query: 158 RKKRLQLKQAS---ESKLLEIQTEKNKQ-----KIDLDSMENS--ERIKIIRQNLQMEIK 207
K +LQ++ + E K L+ EK K+ K++L+SM+ + ++QN + E +
Sbjct: 898 -KHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQ 956
Query: 208 ITTVIQHVFQNLILGSKVNWAEDPALKEIVLQ 239
+ I + Q+ K A LK VLQ
Sbjct: 957 LQGNINELKQSSEQKKKQIEALQGELKIAVLQ 988
Score = 39.7 bits (91), Expect = 0.002
Identities = 42/167 (25%), Positives = 85/167 (50%), Gaps = 11/167 (6%)
Query: 48 AQTKQQLLEY-KSMVDASEEKT--PEQIMQEKQIEAKIEDLE--NEIEEVKVAFEIKKLA 102
A+ +QQL E K++ D +EK+ ++++ EK A+IE+++ E E K+ E+K
Sbjct: 1092 AKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHK 1151
Query: 103 LDRMRLSTALKKNLEKISRQSSVLM---DNMKHLLEL---NKLIMKSQQESWDLEEKLLD 156
L+ ++ T LK + + +Q L D++K +E N+ I+K Q + + E K
Sbjct: 1152 LESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEF 1211
Query: 157 IRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQ 203
I K+ + E ++ + E+N+ K+ + +E + +++ Q
Sbjct: 1212 IEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQ 1258
Score = 36.6 bits (83), Expect = 0.021
Identities = 40/195 (20%), Positives = 89/195 (45%), Gaps = 29/195 (14%)
Query: 38 DRMTLLLRLRAQTKQQLL---EYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKV 94
D L RL Q K+++ E + +D ++++ EQ ++ AK+ + +N++E+V
Sbjct: 457 DLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLR 516
Query: 95 AFEIKKLALDRMR-LSTALKKNLEKISRQSSVLMDNMK----HLLELNKLIMKS---QQE 146
K + + L K+N+ + ++ L ++ LN+L K+ Q++
Sbjct: 517 QIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQ 576
Query: 147 SWDLEEKLLDIRKKRLQLKQ--------------ASESKLLEIQTEKNKQKIDLDSMENS 192
L EKL + + Q ++ A++ ++L ++T N +L+S N
Sbjct: 577 VTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVN----ELNSQLNE 632
Query: 193 ERIKIIRQNLQMEIK 207
+ K+ + ++Q++ K
Sbjct: 633 SKEKVSQLDIQIKAK 647
Score = 36.6 bits (83), Expect = 0.021
Identities = 44/181 (24%), Positives = 83/181 (45%), Gaps = 14/181 (7%)
Query: 36 SEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVA 95
SE + + L+ + K +L+ + + +++ + + + KI L+N E+ +
Sbjct: 968 SEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQET 1027
Query: 96 FEIKKLALD-------RMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESW 148
F K+L D + LK EK+S L+ N + NKLI + +
Sbjct: 1028 F--KQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKA 1085
Query: 149 DLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKI 208
LE+ D KK QL++ ++ L +IQ EK+ ++ +L + E S+ +I + E +I
Sbjct: 1086 TLEQ---DSAKKEQQLQERCKA-LQDIQKEKSLKEKELVN-EKSKLAEIEEIKCRQEKEI 1140
Query: 209 T 209
T
Sbjct: 1141 T 1141
Score = 33.1 bits (74), Expect = 0.23
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 20/170 (11%)
Query: 48 AQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI--------------EEVK 93
A K + E +S+ +A+E+K + + I+DL+ E+ E V+
Sbjct: 173 ADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQ 232
Query: 94 VAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEK 153
V + + L+R R S LK +K+ Q + + + +L + K QE ++
Sbjct: 233 VQTLMDNMTLERERESEKLKDECKKLQSQYA---SSEATISQLRSELAKGPQEVAVYVQE 289
Query: 154 LLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQ 203
L ++ +L Q +++ L E +K + L+ N E + ++N+Q
Sbjct: 290 LQKLKSSVNELTQKNQT-LTENLLKKEQDYTKLEEKHNEESVS--KKNIQ 336
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 45.8 bits (107), Expect = 3e-05
Identities = 46/183 (25%), Positives = 84/183 (45%), Gaps = 21/183 (11%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI-----EE 91
EDR L R + QQ+L+ + ++ E + +++ EAKI+ LE+EI +
Sbjct: 935 EDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN 994
Query: 92 VKVAFEIKKLALDRMRLSTAL------KKNLEKISRQSSVLMDNM--------KHLLELN 137
K++ E K L L+T L KNL K+ + ++ + K EL
Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1054
Query: 138 KLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKI 197
KL K + ++ D E++ D++ + +LK K E+Q ++D + + + +K
Sbjct: 1055 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA--LARLDDEIAQKNNALKK 1112
Query: 198 IRQ 200
IR+
Sbjct: 1113 IRE 1115
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/161 (21%), Positives = 81/161 (50%), Gaps = 13/161 (8%)
Query: 38 DRMTLLLRLRAQTKQQLL-EYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
+ M + L + Q +++L E ++ ++ E++ + + K++ ++ DLE ++EE + A
Sbjct: 907 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 97 EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLD 156
+ KL L+++ +KK ++I ++MD+ + L + ++ ++ DL L +
Sbjct: 967 Q--KLQLEKVTAEAKIKKLEDEI-----LVMDDQNNKLSKERKLL--EERISDLTTNLAE 1017
Query: 157 IRKKR---LQLKQASESKLLEIQTEKNKQKIDLDSMENSER 194
+K +LK ES + E++ K++ +E +R
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1058
Score = 38.1 bits (87), Expect = 0.007
Identities = 41/178 (23%), Positives = 83/178 (46%), Gaps = 23/178 (12%)
Query: 44 LRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIED----LENEIEEV-----KV 94
LR+ Q KQ++ K ++A ++ + ++ A++ D L+NE+E V +
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1299
Query: 95 AFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
+ KLA D LS+ L+ E +L + + L ++ + + ++E L+++L
Sbjct: 1300 EGKAIKLAKDVASLSSQLQDTQE-------LLQEETRQKLNVSTKLRQLEEERNSLQDQL 1352
Query: 155 LDIRKKRLQLKQASESKL--LEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITT 210
+ ++ KQ E + L IQ +K+K+ D E ++ ++ Q EI+ T
Sbjct: 1353 ----DEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIENLT 1405
Score = 33.5 bits (75), Expect = 0.18
Identities = 34/186 (18%), Positives = 83/186 (44%), Gaps = 23/186 (12%)
Query: 47 RAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLE--------------NEIEEV 92
R Q ++QL EY++ ++ ++ +K++E ++DLE ++ ++
Sbjct: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKL 1650
Query: 93 KVAF-----EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQES 147
+ E++ R + K+N +K + LM + L + ++ E
Sbjct: 1651 QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK 1710
Query: 148 WDLEEKLLDIRKKRLQL---KQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQM 204
+L E+L R L K+ E+++ +++ E +++ ++++M + R K +Q Q+
Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR-KATQQAEQL 1769
Query: 205 EIKITT 210
++ T
Sbjct: 1770 SNELAT 1775
Score = 30.8 bits (68), Expect = 1.1
Identities = 32/166 (19%), Positives = 74/166 (44%), Gaps = 13/166 (7%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
E++ L +L+ + + + E + + E+ E ++++E D +I +++
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 97 -EIK-KLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
E+K +LA L AL + ++I+++++ L K I + + DL+E L
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNAL-----------KKIRELEGHISDLQEDL 1127
Query: 155 LDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQ 200
R R + ++ E++ K + + LDS + ++ R+
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1173
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 45.8 bits (107), Expect = 3e-05
Identities = 46/183 (25%), Positives = 84/183 (45%), Gaps = 21/183 (11%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI-----EE 91
EDR L R + QQ+L+ + ++ E + +++ EAKI+ LE+EI +
Sbjct: 942 EDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN 1001
Query: 92 VKVAFEIKKLALDRMRLSTAL------KKNLEKISRQSSVLMDNM--------KHLLELN 137
K++ E K L L+T L KNL K+ + ++ + K EL
Sbjct: 1002 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1061
Query: 138 KLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKI 197
KL K + ++ D E++ D++ + +LK K E+Q ++D + + + +K
Sbjct: 1062 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA--LARLDDEIAQKNNALKK 1119
Query: 198 IRQ 200
IR+
Sbjct: 1120 IRE 1122
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/161 (21%), Positives = 81/161 (50%), Gaps = 13/161 (8%)
Query: 38 DRMTLLLRLRAQTKQQLL-EYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
+ M + L + Q +++L E ++ ++ E++ + + K++ ++ DLE ++EE + A
Sbjct: 914 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 973
Query: 97 EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLD 156
+ KL L+++ +KK ++I ++MD+ + L + ++ ++ DL L +
Sbjct: 974 Q--KLQLEKVTAEAKIKKLEDEI-----LVMDDQNNKLSKERKLL--EERISDLTTNLAE 1024
Query: 157 IRKKR---LQLKQASESKLLEIQTEKNKQKIDLDSMENSER 194
+K +LK ES + E++ K++ +E +R
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1065
Score = 38.1 bits (87), Expect = 0.007
Identities = 41/178 (23%), Positives = 83/178 (46%), Gaps = 23/178 (12%)
Query: 44 LRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIED----LENEIEEV-----KV 94
LR+ Q KQ++ K ++A ++ + ++ A++ D L+NE+E V +
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1306
Query: 95 AFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
+ KLA D LS+ L+ E +L + + L ++ + + ++E L+++L
Sbjct: 1307 EGKAIKLAKDVASLSSQLQDTQE-------LLQEETRQKLNVSTKLRQLEEERNSLQDQL 1359
Query: 155 LDIRKKRLQLKQASESKL--LEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITT 210
+ ++ KQ E + L IQ +K+K+ D E ++ ++ Q EI+ T
Sbjct: 1360 ----DEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIENLT 1412
Score = 33.5 bits (75), Expect = 0.18
Identities = 34/186 (18%), Positives = 83/186 (44%), Gaps = 23/186 (12%)
Query: 47 RAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLE--------------NEIEEV 92
R Q ++QL EY++ ++ ++ +K++E ++DLE ++ ++
Sbjct: 1598 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKL 1657
Query: 93 KVAF-----EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQES 147
+ E++ R + K+N +K + LM + L + ++ E
Sbjct: 1658 QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK 1717
Query: 148 WDLEEKLLDIRKKRLQL---KQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQM 204
+L E+L R L K+ E+++ +++ E +++ ++++M + R K +Q Q+
Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR-KATQQAEQL 1776
Query: 205 EIKITT 210
++ T
Sbjct: 1777 SNELAT 1782
Score = 30.8 bits (68), Expect = 1.1
Identities = 32/166 (19%), Positives = 74/166 (44%), Gaps = 13/166 (7%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
E++ L +L+ + + + E + + E+ E ++++E D +I +++
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 97 -EIK-KLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
E+K +LA L AL + ++I+++++ L K I + + DL+E L
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNAL-----------KKIRELEGHISDLQEDL 1134
Query: 155 LDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQ 200
R R + ++ E++ K + + LDS + ++ R+
Sbjct: 1135 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1180
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 45.8 bits (107), Expect = 3e-05
Identities = 46/183 (25%), Positives = 84/183 (45%), Gaps = 21/183 (11%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI-----EE 91
EDR L R + QQ+L+ + ++ E + +++ EAKI+ LE+EI +
Sbjct: 942 EDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN 1001
Query: 92 VKVAFEIKKLALDRMRLSTAL------KKNLEKISRQSSVLMDNM--------KHLLELN 137
K++ E K L L+T L KNL K+ + ++ + K EL
Sbjct: 1002 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1061
Query: 138 KLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKI 197
KL K + ++ D E++ D++ + +LK K E+Q ++D + + + +K
Sbjct: 1062 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA--LARLDDEIAQKNNALKK 1119
Query: 198 IRQ 200
IR+
Sbjct: 1120 IRE 1122
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/161 (21%), Positives = 81/161 (50%), Gaps = 13/161 (8%)
Query: 38 DRMTLLLRLRAQTKQQLL-EYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
+ M + L + Q +++L E ++ ++ E++ + + K++ ++ DLE ++EE + A
Sbjct: 914 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 973
Query: 97 EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLD 156
+ KL L+++ +KK ++I ++MD+ + L + ++ ++ DL L +
Sbjct: 974 Q--KLQLEKVTAEAKIKKLEDEI-----LVMDDQNNKLSKERKLL--EERISDLTTNLAE 1024
Query: 157 IRKKR---LQLKQASESKLLEIQTEKNKQKIDLDSMENSER 194
+K +LK ES + E++ K++ +E +R
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1065
Score = 38.1 bits (87), Expect = 0.007
Identities = 41/178 (23%), Positives = 83/178 (46%), Gaps = 23/178 (12%)
Query: 44 LRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIED----LENEIEEV-----KV 94
LR+ Q KQ++ K ++A ++ + ++ A++ D L+NE+E V +
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1306
Query: 95 AFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
+ KLA D LS+ L+ E +L + + L ++ + + ++E L+++L
Sbjct: 1307 EGKAIKLAKDVASLSSQLQDTQE-------LLQEETRQKLNVSTKLRQLEEERNSLQDQL 1359
Query: 155 LDIRKKRLQLKQASESKL--LEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITT 210
+ ++ KQ E + L IQ +K+K+ D E ++ ++ Q EI+ T
Sbjct: 1360 ----DEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIENLT 1412
Score = 33.5 bits (75), Expect = 0.18
Identities = 34/186 (18%), Positives = 83/186 (44%), Gaps = 23/186 (12%)
Query: 47 RAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLE--------------NEIEEV 92
R Q ++QL EY++ ++ ++ +K++E ++DLE ++ ++
Sbjct: 1598 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKL 1657
Query: 93 KVAF-----EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQES 147
+ E++ R + K+N +K + LM + L + ++ E
Sbjct: 1658 QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK 1717
Query: 148 WDLEEKLLDIRKKRLQL---KQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQM 204
+L E+L R L K+ E+++ +++ E +++ ++++M + R K +Q Q+
Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR-KATQQAEQL 1776
Query: 205 EIKITT 210
++ T
Sbjct: 1777 SNELAT 1782
Score = 30.8 bits (68), Expect = 1.1
Identities = 32/166 (19%), Positives = 74/166 (44%), Gaps = 13/166 (7%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
E++ L +L+ + + + E + + E+ E ++++E D +I +++
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 97 -EIK-KLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
E+K +LA L AL + ++I+++++ L K I + + DL+E L
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNAL-----------KKIRELEGHISDLQEDL 1134
Query: 155 LDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQ 200
R R + ++ E++ K + + LDS + ++ R+
Sbjct: 1135 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1180
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 45.8 bits (107), Expect = 3e-05
Identities = 46/183 (25%), Positives = 84/183 (45%), Gaps = 21/183 (11%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI-----EE 91
EDR L R + QQ+L+ + ++ E + +++ EAKI+ LE+EI +
Sbjct: 935 EDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN 994
Query: 92 VKVAFEIKKLALDRMRLSTAL------KKNLEKISRQSSVLMDNM--------KHLLELN 137
K++ E K L L+T L KNL K+ + ++ + K EL
Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1054
Query: 138 KLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKI 197
KL K + ++ D E++ D++ + +LK K E+Q ++D + + + +K
Sbjct: 1055 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA--LARLDDEIAQKNNALKK 1112
Query: 198 IRQ 200
IR+
Sbjct: 1113 IRE 1115
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/161 (21%), Positives = 81/161 (50%), Gaps = 13/161 (8%)
Query: 38 DRMTLLLRLRAQTKQQLL-EYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
+ M + L + Q +++L E ++ ++ E++ + + K++ ++ DLE ++EE + A
Sbjct: 907 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 97 EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLD 156
+ KL L+++ +KK ++I ++MD+ + L + ++ ++ DL L +
Sbjct: 967 Q--KLQLEKVTAEAKIKKLEDEI-----LVMDDQNNKLSKERKLL--EERISDLTTNLAE 1017
Query: 157 IRKKR---LQLKQASESKLLEIQTEKNKQKIDLDSMENSER 194
+K +LK ES + E++ K++ +E +R
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1058
Score = 38.1 bits (87), Expect = 0.007
Identities = 41/178 (23%), Positives = 83/178 (46%), Gaps = 23/178 (12%)
Query: 44 LRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIED----LENEIEEV-----KV 94
LR+ Q KQ++ K ++A ++ + ++ A++ D L+NE+E V +
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1299
Query: 95 AFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
+ KLA D LS+ L+ E +L + + L ++ + + ++E L+++L
Sbjct: 1300 EGKAIKLAKDVASLSSQLQDTQE-------LLQEETRQKLNVSTKLRQLEEERNSLQDQL 1352
Query: 155 LDIRKKRLQLKQASESKL--LEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITT 210
+ ++ KQ E + L IQ +K+K+ D E ++ ++ Q EI+ T
Sbjct: 1353 ----DEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIENLT 1405
Score = 33.5 bits (75), Expect = 0.18
Identities = 34/186 (18%), Positives = 83/186 (44%), Gaps = 23/186 (12%)
Query: 47 RAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLE--------------NEIEEV 92
R Q ++QL EY++ ++ ++ +K++E ++DLE ++ ++
Sbjct: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKL 1650
Query: 93 KVAF-----EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQES 147
+ E++ R + K+N +K + LM + L + ++ E
Sbjct: 1651 QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK 1710
Query: 148 WDLEEKLLDIRKKRLQL---KQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQM 204
+L E+L R L K+ E+++ +++ E +++ ++++M + R K +Q Q+
Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR-KATQQAEQL 1769
Query: 205 EIKITT 210
++ T
Sbjct: 1770 SNELAT 1775
Score = 30.8 bits (68), Expect = 1.1
Identities = 32/166 (19%), Positives = 74/166 (44%), Gaps = 13/166 (7%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF 96
E++ L +L+ + + + E + + E+ E ++++E D +I +++
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 97 -EIK-KLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
E+K +LA L AL + ++I+++++ L K I + + DL+E L
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNAL-----------KKIRELEGHISDLQEDL 1127
Query: 155 LDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQ 200
R R + ++ E++ K + + LDS + ++ R+
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1173
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 45.8 bits (107), Expect = 3e-05
Identities = 51/212 (24%), Positives = 94/212 (44%), Gaps = 27/212 (12%)
Query: 43 LLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLE----NEIEEVKVAFEI 98
L LR + +Q+L K D E E+I QE+ EDLE + ++++ F
Sbjct: 1953 LRMLRKEHQQELEILKKEYDQERE---EKIKQEQ------EDLELKHNSTLKQLMREFNT 2003
Query: 99 KKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLE------E 152
+ LA L +K+ + K + L+++ H E N+L+ K ++ DL+ E
Sbjct: 2004 Q-LAQKEQELEMTIKETINKAQEVEAELLES--HQEETNQLLKKIAEKDDDLKRTAKRYE 2060
Query: 153 KLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVI 212
++LD R++ + K LE +K +QK++ + ++ + I+ Q+ K T +
Sbjct: 2061 EILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLIS 2120
Query: 213 QHVFQNLILGSKVNWAEDPALKEIVLQLEKNV 244
+ +++ ED K EKNV
Sbjct: 2121 DSKLKEQEFREQIHNLEDRLKK-----YEKNV 2147
Score = 42.0 bits (97), Expect = 5e-04
Identities = 50/206 (24%), Positives = 86/206 (41%), Gaps = 45/206 (21%)
Query: 46 LRAQTKQQLLEYKSMVDASE---EKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLA 102
L+ +Q+ +E+K +V + E E+ + K+ E KI LEN++ +K E KK
Sbjct: 1548 LKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKE 1607
Query: 103 LDRMRLST--------ALKKNLE----------------KISRQSSVLMDNMK------- 131
L+ + LS AL+ LE KI+ L+ M+
Sbjct: 1608 LEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYK 1667
Query: 132 -----HLLELNKLIMKSQQESWDLEEKLLDIRKKRLQL----KQASESKLLEIQTEKNKQ 182
HL ELN + + ++E LEEKL + + + + A Q E + Q
Sbjct: 1668 KGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQ 1727
Query: 183 KIDLDSMENSERIKIIRQNLQMEIKI 208
+ E E+I ++++NL + K+
Sbjct: 1728 GCVQKTYE--EKISVLQRNLTEKEKL 1751
Score = 37.0 bits (84), Expect = 0.016
Identities = 33/165 (20%), Positives = 77/165 (46%), Gaps = 10/165 (6%)
Query: 49 QTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRL 108
Q +L ++S A+ E+T Q Q++ K+ DLE E + + ++ ++ + +
Sbjct: 795 QASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETE--RILLTKQVAEVEAQKKDV 852
Query: 109 STALKKN-------LEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKR 161
T L + ++++ +Q+S + +K L ++ + ++ + + +++L ++
Sbjct: 853 CTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENM 912
Query: 162 LQLKQASESKLLEIQTEKNKQKIDLDSMENSE-RIKIIRQNLQME 205
+ + + K +EI T+K K D + N E K Q +ME
Sbjct: 913 ILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKME 957
Score = 32.7 bits (73), Expect = 0.30
Identities = 43/225 (19%), Positives = 98/225 (43%), Gaps = 16/225 (7%)
Query: 1 MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSE-DRMTLLLRLRAQTKQQLLEYKS 59
+E Q ++ +E +S GE V + R LL+ +T Q E +
Sbjct: 251 LEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCT 310
Query: 60 MVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFE-------IKKLALDRMRLSTAL 112
++ + +E EQ+ + Q KI+DL + E+ K+ + I++L D+ +
Sbjct: 311 LLTSEKEALQEQLDERLQELEKIKDL-HMAEKTKLITQLRDAKNLIEQLEQDKGMVIAET 369
Query: 113 KK----NLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQAS 168
K+ LE + + L +K + + + + +++S E + +K L Q +
Sbjct: 370 KRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKS---ERAAFEELEKALSTAQKT 426
Query: 169 ESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQ 213
E +++ E ++Q ++ ERI + ++ +++ ++ V++
Sbjct: 427 EEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMK 471
Score = 31.2 bits (69), Expect = 0.87
Identities = 36/182 (19%), Positives = 85/182 (46%), Gaps = 25/182 (13%)
Query: 48 AQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEV-KVAFEIKKLALDRM 106
A+TK+Q+ E M EE+ + + KQ+ + E+L + E+ + AFE + AL
Sbjct: 367 AETKRQMHETLEM---KEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTA 423
Query: 107 RLSTALKKNL--EKISRQSSVLMDNMKHLLELNKLIMKSQQESWDL-----EEKLLDIRK 159
+ + ++ L E + ++ + + + L + + + +QE D+ EE++ ++K
Sbjct: 424 QKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQK 483
Query: 160 --------------KRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQME 205
K+LQ ++ + +++ EK++ + S E ++ + + L+++
Sbjct: 484 LHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQ 543
Query: 206 IK 207
K
Sbjct: 544 KK 545
Score = 30.8 bits (68), Expect = 1.1
Identities = 34/179 (18%), Positives = 80/179 (44%), Gaps = 20/179 (11%)
Query: 38 DRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFE 97
++ ++L++R K+++ + A E+ I+ E + E K ++ E ++E+VK +
Sbjct: 908 EKENMILQMREGQKKEIEILTQKLSAKEDSI--HILNE-EYETKFKNQEKKMEKVKQKAK 964
Query: 98 -----IKKLALDRMRLSTALKKNLE----KISRQSSVLMDNMKHLLELNKL-----IMKS 143
+KK LD+ LKK LE ++S++ M + + N + +
Sbjct: 965 EMQETLKKKLLDQ---EAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRL 1021
Query: 144 QQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNL 202
+ + E L ++ ++ L + K L Q E+ ++ ++ E + + ++Q +
Sbjct: 1022 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKI 1080
>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
Length = 1280
Score = 45.1 bits (105), Expect = 6e-05
Identities = 43/171 (25%), Positives = 90/171 (52%), Gaps = 19/171 (11%)
Query: 36 SEDRMTLLLRLRAQTKQQLLEYKSMVDASE----EKTPEQIMQEKQIEAKIEDLENEIEE 91
S R + + ++RA +QQ + +S VD++ E+T ++ Q E +E+ E ++E
Sbjct: 1064 SSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNLDE 1123
Query: 92 VKVA----FEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQES 147
K A EI KL +R+R+S+ + LE+ R+ V M+ KL+++ +
Sbjct: 1124 AKHAEKYEQEITKLK-ERLRVSS---RRLEEYERRLLVQEQQMQ------KLLLEYKARL 1173
Query: 148 WDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKII 198
D EE+L ++++ ++ S+L+ ++ E K ++ ++ ++++ KII
Sbjct: 1174 EDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQ-KII 1223
>gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]
Length = 1139
Score = 45.1 bits (105), Expect = 6e-05
Identities = 43/171 (25%), Positives = 90/171 (52%), Gaps = 19/171 (11%)
Query: 36 SEDRMTLLLRLRAQTKQQLLEYKSMVDASE----EKTPEQIMQEKQIEAKIEDLENEIEE 91
S R + + ++RA +QQ + +S VD++ E+T ++ Q E +E+ E ++E
Sbjct: 923 SSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNLDE 982
Query: 92 VKVA----FEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQES 147
K A EI KL +R+R+S+ + LE+ R+ V M+ KL+++ +
Sbjct: 983 AKHAEKYEQEITKLK-ERLRVSS---RRLEEYERRLLVQEQQMQ------KLLLEYKARL 1032
Query: 148 WDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKII 198
D EE+L ++++ ++ S+L+ ++ E K ++ ++ ++++ KII
Sbjct: 1033 EDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQ-KII 1082
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 44.7 bits (104), Expect = 8e-05
Identities = 45/183 (24%), Positives = 83/183 (45%), Gaps = 38/183 (20%)
Query: 44 LRLRAQTKQQLLE-----YKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEI 98
+R R K+Q LE +S V+ EE+ ++K+++A I+DLE +++E + A +
Sbjct: 909 MRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQ- 967
Query: 99 KKLALDRMRLSTALKKNLE---------------------KISRQSSVLMDNMKHLLELN 137
KL L+++ +KK E +I+ SS L + + L
Sbjct: 968 -KLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLA 1026
Query: 138 KLIMKSQQESWDLEEKLLDIRKKRLQLKQAS----------ESKLLEIQTEKNKQKIDLD 187
K+ K + DLEE+L K R +L++A + ++ E+Q + ++ K+ L
Sbjct: 1027 KIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLA 1086
Query: 188 SME 190
E
Sbjct: 1087 KKE 1089
Score = 43.9 bits (102), Expect = 1e-04
Identities = 38/184 (20%), Positives = 88/184 (47%), Gaps = 18/184 (9%)
Query: 27 QVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLE 86
Q+A QA E ++ L A+ +++L + D + ++++A+I +L+
Sbjct: 1070 QIAELQAQIDELKLQL-----AKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQ 1124
Query: 87 NEIEEVKVAF-----EIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIM 141
+ E K + + + L+ + L T L+ L+ + Q + + + EL K +
Sbjct: 1125 EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAL- 1183
Query: 142 KSQQESWDLEEKLLDIRKKRLQL-----KQASESKLLEIQTEKNKQKIDLDSMENSERIK 196
++E+ + E ++ D+R++ +Q ++K + EKNKQ ++ D+ E + +K
Sbjct: 1184 --EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVK 1241
Query: 197 IIRQ 200
+++Q
Sbjct: 1242 VLQQ 1245
Score = 36.2 bits (82), Expect = 0.027
Identities = 40/164 (24%), Positives = 79/164 (48%), Gaps = 19/164 (11%)
Query: 34 ACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVK 93
A + ++ L + ++A Q + ++ + +EEK I Q +++EA++ED E + +
Sbjct: 1557 ATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELED-ERKQRALA 1615
Query: 94 VAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEK 153
VA + KK+ +D K+LE ++ D E+ K + K Q + D + +
Sbjct: 1616 VASK-KKMEID--------LKDLEAQIEAANKARD------EVIKQLRKLQAQMKDYQRE 1660
Query: 154 LLDIRKKRLQL---KQASESKLLEIQTEKNKQKIDLDSMENSER 194
L + R R ++ + SE KL ++ E + + +L S E + R
Sbjct: 1661 LEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARR 1704
Score = 35.8 bits (81), Expect = 0.035
Identities = 36/182 (19%), Positives = 78/182 (42%), Gaps = 7/182 (3%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI-EEVKVA 95
ED+ + ++ + + ++ E S + EEK + E I DLE + +E K
Sbjct: 991 EDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTR 1050
Query: 96 FEIKKLALDRMRLSTALKKNLEKISRQSSVL-MDNMKHLLELNKLIMKSQQESWDLEEKL 154
E++K +T L+ + ++ Q L + K EL + + E+ L
Sbjct: 1051 QELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNAL 1110
Query: 155 LDIRKKRLQLKQASESKLLEIQTEK-NKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQ 213
+R+ + Q+ + E + ++EK ++ K + + SE ++ ++ L+ + T Q
Sbjct: 1111 KVVRELQAQIAELQE----DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166
Query: 214 HV 215
+
Sbjct: 1167 EL 1168
Score = 35.0 bits (79), Expect = 0.060
Identities = 40/170 (23%), Positives = 76/170 (44%), Gaps = 33/170 (19%)
Query: 52 QQLLEYKSMV-----------DASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEI-- 98
QQLLE K+++ +EE +++++E + DLE+ +EE + +I
Sbjct: 883 QQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQ 942
Query: 99 ---KKLALDRMRLSTAL--------KKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQES 147
KK+ L L K LEK++ ++ + +E L+++ Q
Sbjct: 943 NEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKI------KKMEEEILLLEDQNSK 996
Query: 148 WDLEEKLLDIRKKRLQLKQA-SESKLLEIQTEKNKQKIDLDSMENSERIK 196
+ E+KL++ R + A E K + +NKQ++ + +E ER+K
Sbjct: 997 FIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLE--ERLK 1044
Score = 33.9 bits (76), Expect = 0.13
Identities = 30/177 (16%), Positives = 77/177 (43%), Gaps = 9/177 (5%)
Query: 31 AQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIE 90
+Q A E++ L ++R + + + + + + E+ E +++++ + DL+++I
Sbjct: 1013 SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA 1072
Query: 91 EVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDL 150
E++ + KL L K E++ + D H K++ + Q + +L
Sbjct: 1073 ELQAQIDELKLQL---------AKKEEELQGALARGDDETLHKNNALKVVRELQAQIAEL 1123
Query: 151 EEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIK 207
+E + R + ++ E++ K + + LD+ + ++ R+ E+K
Sbjct: 1124 QEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELK 1180
Score = 33.9 bits (76), Expect = 0.13
Identities = 46/190 (24%), Positives = 81/190 (42%), Gaps = 34/190 (17%)
Query: 45 RLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALD 104
R R +Q+ E + S + +++++EA+I LE E+EE + E L D
Sbjct: 1701 RARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNME---LLND 1757
Query: 105 RMRLSTALKKNLE---KISRQSSVLMDNMKHLLELNKLIMKSQQESWD------------ 149
R R +T L R ++ DN + LE +K++ + +
Sbjct: 1758 RFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATIS 1817
Query: 150 --------LEEKLLDIRKKRL---QLKQASESKLLEI--QTEKNKQKID--LDSMENSE- 193
LEE+L K+R +L + +E KL EI Q E ++ D + ME +
Sbjct: 1818 ALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANA 1877
Query: 194 RIKIIRQNLQ 203
R+K +++ L+
Sbjct: 1878 RMKQLKRQLE 1887
Score = 30.4 bits (67), Expect = 1.5
Identities = 31/135 (22%), Positives = 66/135 (48%), Gaps = 8/135 (5%)
Query: 46 LRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAF-EIKKLALD 104
L+ +T+Q+L + EEK Q QE++ EA+ ++LE ++ ++ + KK D
Sbjct: 1324 LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEAR-KNLEKQVLALQSQLADTKKKVDD 1382
Query: 105 RMRLSTALKKNLEKISRQSSVLMDNMKH-LLELNKLIMKSQQESWDLEEKLLDIRKKR-- 161
+ +L++ +K+ + + L ++ L +KL + +L++ +D+ +R
Sbjct: 1383 DLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQV 1442
Query: 162 ---LQLKQASESKLL 173
L+ KQ +LL
Sbjct: 1443 ASNLEKKQKKFDQLL 1457
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 44.7 bits (104), Expect = 8e-05
Identities = 37/170 (21%), Positives = 85/170 (50%), Gaps = 11/170 (6%)
Query: 27 QVAGAQAACSEDRMTLLLRLRAQTKQQLLE-YKSMVDASEEKTPEQIMQEKQIEAKIEDL 85
++ Q + + D LL ++ K++L + K +DA E++T ++ ++++
Sbjct: 564 RIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKL-------SEMDSF 616
Query: 86 ENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQ 145
N+++E++ + ++LAL++ L + L++I R+ LM K E + + ++
Sbjct: 617 NNQLKELRETYNTQQLALEQ--LYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKE 674
Query: 146 ESWDLE-EKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSER 194
W K + ++KRLQ ++ E E + + KQ+ D D+++ E+
Sbjct: 675 NLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEK 724
Score = 35.0 bits (79), Expect = 0.060
Identities = 45/199 (22%), Positives = 90/199 (45%), Gaps = 37/199 (18%)
Query: 44 LRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI-----------EEV 92
+RL+ QT+ K+ ++ +++ +IM+ KQ++ ++++ +N++ E +
Sbjct: 512 VRLKKQTQ------KTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERI 565
Query: 93 K-VAFE---------IKKLALDRMRLSTALKKNLEKISRQSSVLMDNM----KHLLELNK 138
K + F + K +L++ L LK+ L+ + ++++ + M L EL +
Sbjct: 566 KNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKELRE 625
Query: 139 LIMKSQQESWDL----EEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSER 194
Q L +KL +I +KRL+L Q + KL + K KQ + EN +
Sbjct: 626 TYNTQQLALEQLYKIKRDKLKEIERKRLELMQ--KKKLEDEAARKAKQGKENLWKENLRK 683
Query: 195 IKIIRQNLQMEIKITTVIQ 213
+ +Q E K IQ
Sbjct: 684 EEEEKQKRLQEEKTQEKIQ 702
Score = 32.0 bits (71), Expect = 0.51
Identities = 34/148 (22%), Positives = 67/148 (45%), Gaps = 7/148 (4%)
Query: 47 RAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRM 106
R Q + Q E+K ++ + ++ ++ ++ E + +D+E + ++L +R+
Sbjct: 406 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 465
Query: 107 RLSTALKKNLEKISRQSSVLMDNMKHL---LELNKLIMKSQQESWDLEEKLLDIRKKRLQ 163
R L +K Q ++ N K LEL L K QQ S L++ L + ++ +
Sbjct: 466 RRQELLN---QKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTE 522
Query: 164 LKQASESKLLEIQTEKNKQKIDLDSMEN 191
L+ + LEI K Q+ +L +N
Sbjct: 523 LEVLDKQCDLEIMEIKQLQQ-ELQEYQN 549
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 44.3 bits (103), Expect = 1e-04
Identities = 50/182 (27%), Positives = 94/182 (51%), Gaps = 21/182 (11%)
Query: 37 EDRMTLLLRLRAQTKQQL-LEYKSMVDASEEKTPEQIMQEKQIEAKIEDL---ENEIEEV 92
E++M L++ + + Q+ E S+ DA EE+ + I + Q+EAKI+++ + EE+
Sbjct: 878 EEKMVTLMQEKNDLQLQVQAEADSLADA-EERCDQLIKTKIQLEAKIKEVTERAEDEEEI 936
Query: 93 KVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEE 152
KK L+ + LKK+++ + + ++ KH E NK + +E L+E
Sbjct: 937 NAELTAKKRKLEDE--CSELKKDIDDL-ELTLAKVEKEKHATE-NK-VKNLTEEMAGLDE 991
Query: 153 KLLDIRKKRLQLKQASESKLLEIQTEKN------KQKIDL----DSMENS-ERIKIIRQN 201
+ + K++ L++A + L ++Q E++ K KI L D +E S E+ K IR +
Sbjct: 992 TIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMD 1051
Query: 202 LQ 203
L+
Sbjct: 1052 LE 1053
Score = 38.5 bits (88), Expect = 0.005
Identities = 41/185 (22%), Positives = 86/185 (46%), Gaps = 26/185 (14%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIE-EVKVA 95
ED++ L + + + +QQ+ + + ++ QEK+I +E + ++E ++K+A
Sbjct: 1018 EDKVNTLTKAKIKLEQQVDDLEGSLE-----------QEKKIRMDLERAKRKLEGDLKLA 1066
Query: 96 FE-IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
E + D+ +L LKK ++S S + D ++L K I + Q +LEE+
Sbjct: 1067 QESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEE- 1125
Query: 155 LDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQH 214
++ ++AS +K EK + + + E SER++ +I++ +
Sbjct: 1126 -------IEAERASRAK-----AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1173
Query: 215 VFQNL 219
FQ +
Sbjct: 1174 EFQKM 1178
Score = 38.5 bits (88), Expect = 0.005
Identities = 35/174 (20%), Positives = 84/174 (48%), Gaps = 10/174 (5%)
Query: 36 SEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVA 95
S D++ L R +Q++ + + ++ E +KQ+E + +L+ +EE + +
Sbjct: 1495 SLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEAS 1554
Query: 96 FEIKKLALDRMRLS-TALKKNLEKISRQSSVLMDNMKHLLELNKL-IMKSQQESWDLEEK 153
E ++ + R++L +K +++ + +D MK N + I++S Q + D E
Sbjct: 1555 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKR----NHIRIVESMQSTLDAE-- 1608
Query: 154 LLDIRKKRLQLKQASESKLLEIQTEKN-KQKIDLDSMENSERIKIIRQNLQMEI 206
+ R ++LK+ E L E++ + N ++ +++ N + I ++ Q+ +
Sbjct: 1609 -IRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHL 1661
Score = 38.5 bits (88), Expect = 0.005
Identities = 43/196 (21%), Positives = 86/196 (43%), Gaps = 22/196 (11%)
Query: 32 QAACSEDRMTL--LLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI 89
QA E R TL R R +Q+LL+ V + I +K++E I ++ E+
Sbjct: 1686 QAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEM 1745
Query: 90 EEV-----KVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQ 144
E++ + KK D ++ LKK + +S ++ MK LE + + Q
Sbjct: 1746 EDIIQEARNAEEKAKKAITDAAMMAEELKK-----EQDTSAHLERMKKNLE--QTVKDLQ 1798
Query: 145 QESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQM 204
+ E+ L KK++Q LE + + + +++ + N E +K +R++ +
Sbjct: 1799 HRLDEAEQLALKGGKKQIQ--------KLEARVRELEGEVESEQKRNVEAVKGLRKHERK 1850
Query: 205 EIKITTVIQHVFQNLI 220
++T + +N++
Sbjct: 1851 VKELTYQTEEDRKNIL 1866
Score = 34.7 bits (78), Expect = 0.079
Identities = 47/188 (25%), Positives = 87/188 (46%), Gaps = 33/188 (17%)
Query: 32 QAACSEDRMTL------LLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQ-----IEA 80
QAA E +L +LR++ + Q KS VD + E+I Q K+ +E+
Sbjct: 1545 QAALEEAEASLEHEEGKILRIQLELNQ----VKSEVDRKIAEKDEEIDQMKRNHIRIVES 1600
Query: 81 KIEDLENEIEEVKVAFEIKKLA---LDRMRL-----STALKKNLEKISRQSSVLMDNMKH 132
L+ EI A +KK L+ M + + + L ++L D H
Sbjct: 1601 MQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLH 1660
Query: 133 LLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEI--QTEKNKQKIDLDSME 190
L + ++SQ+ DL+E+L + ++R L QA +L QTE++++ + + ++
Sbjct: 1661 LDDA----LRSQE---DLKEQLAMV-ERRANLLQAEIEELRATLEQTERSRKIAEQELLD 1712
Query: 191 NSERIKII 198
SER++++
Sbjct: 1713 ASERVQLL 1720
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 44.3 bits (103), Expect = 1e-04
Identities = 40/168 (23%), Positives = 90/168 (53%), Gaps = 18/168 (10%)
Query: 38 DRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFE 97
++ +++L+L ++ L E++ + S + T + ++E +++ +I L N ++++K +
Sbjct: 1149 EKESIILKL----ERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQ 1204
Query: 98 IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDI 157
+K+ + R T +K E++S SS N+K L+ + +++ DL+EKL D
Sbjct: 1205 LKEEEEETNRQET--EKLKEELSA-SSARTQNLKADLQ------RKEEDYADLKEKLTDA 1255
Query: 158 RKKRLQLKQ-----ASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQ 200
+K+ Q+++ E KLL I+ + ++K + S E + + I+Q
Sbjct: 1256 KKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQ 1303
Score = 42.0 bits (97), Expect = 5e-04
Identities = 43/206 (20%), Positives = 96/206 (46%), Gaps = 14/206 (6%)
Query: 47 RAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRM 106
R Q + + S ++A E+ E + + +IE+LE +IE K+ E+K +
Sbjct: 1003 RIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIE--KLQAEVKGYKDENN 1060
Query: 107 RLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQ 166
RL KN + + ++ L+ +K L+ + + Q + +++ ++ +L Q
Sbjct: 1061 RLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQ------IQHVVEGKRALSELTQ 1114
Query: 167 ---ASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQN--LQMEIKITTVIQHVFQNLIL 221
++K+ E++T QK++ E+ + +++ L++E + +H+ Q+ +
Sbjct: 1115 GVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHL-QDSVK 1173
Query: 222 GSKVNWAEDPALKEIVLQLEKNVDMM 247
+K ++ LKE + QL N+ M
Sbjct: 1174 NTKDLNVKELKLKEEITQLTNNLQDM 1199
Score = 35.4 bits (80), Expect = 0.046
Identities = 39/156 (25%), Positives = 74/156 (47%), Gaps = 22/156 (14%)
Query: 51 KQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLST 110
K++++E M +E+T Q+ Q++ +EAK+E++E ++A E++K L T
Sbjct: 1330 KEKIIEDMRMTLEEQEQT--QVEQDQVLEAKLEEVE------RLATELEKWKEKCNDLET 1381
Query: 111 ALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASES 170
KN ++ +++ D + L L Q E + E+K RKK L+ K +
Sbjct: 1382 ---KNNQRSNKEHENNTDVLGKLTNL-------QDELQESEQKYNADRKKWLEEKMMLIT 1431
Query: 171 KLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEI 206
+ E + +NK+ +R + +Q +MEI
Sbjct: 1432 QAKEAENIRNKEM----KKYAEDRERFFKQQNEMEI 1463
Score = 32.7 bits (73), Expect = 0.30
Identities = 23/101 (22%), Positives = 51/101 (50%), Gaps = 8/101 (7%)
Query: 126 LMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKID 185
L + + ELNK I+ QQE E+K L + K+ Q++ + + E+ +K+K +
Sbjct: 858 LKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQ-- 915
Query: 186 LDSMENSERIKIIRQNLQMEIKITTVIQHVFQNLILGSKVN 226
+ KI++ + ++E ++ +V Q ++ +K++
Sbjct: 916 ------EQEEKIMKLSNEIETATRSITNNVSQIKLMHTKID 950
Score = 27.7 bits (60), Expect = 9.6
Identities = 39/183 (21%), Positives = 81/183 (44%), Gaps = 15/183 (8%)
Query: 34 ACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVK 93
AC E + + A+TK +L++ K + E ++ I + + KI I+E+
Sbjct: 671 ACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELI 730
Query: 94 VAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQE-SWDLEE 152
+ K+ ++ + + +N K + ++ + L+ NKLI E D +
Sbjct: 731 NIIDQKEDTINEFQNLKSHMENTFKCNDKA-----DTSSLIINNKLICNETVEVPKDSKS 785
Query: 153 KLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDS--MENSERIKIIRQNLQMEIKITT 210
K+ RK+ +E++L + + K I + S E+ ++ + +R N+ EI+
Sbjct: 786 KICSERKR------VNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNI-AEIEDIR 838
Query: 211 VIQ 213
V+Q
Sbjct: 839 VLQ 841
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/171 (21%), Positives = 85/171 (49%), Gaps = 4/171 (2%)
Query: 25 PPQVAGAQAA-CSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIE 83
P Q A+A ++ ++ +L+AQ ++ L + + EEK Q + ++ E KI+
Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQVEENEL-WNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
Query: 84 DLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKS 143
+ E +I E + +I++ R + + EK+ RQ ++ + + + L +++ +
Sbjct: 318 EQEEKIREQEE--KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEK 375
Query: 144 QQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSER 194
+++ +LEEK+ + K R Q ++ E + + Q ++ +Q+ + E R
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 426
Score = 43.1 bits (100), Expect = 2e-04
Identities = 30/153 (19%), Positives = 74/153 (48%), Gaps = 7/153 (4%)
Query: 45 RLRAQTKQQLLEYKSMVDASE---EKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKL 101
++R Q ++ + + M D E E+ + QE++I + E + + E+++ E+ +
Sbjct: 489 KIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQE 548
Query: 102 ALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKR 161
++M + EK+ RQ + + + + E + I + +++ W+ EEK+ +++
Sbjct: 549 QEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI----REQ 604
Query: 162 LQLKQASESKLLEIQTEKNKQKIDLDSMENSER 194
++ Q E K+ E + + +Q+ + E R
Sbjct: 605 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637
Score = 38.5 bits (88), Expect = 0.005
Identities = 31/150 (20%), Positives = 71/150 (47%), Gaps = 3/150 (2%)
Query: 57 YKSMVDASEEKTPEQIMQEKQ--IEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKK 114
Y++ + E K +QEK +E++ +++ ++E+K E KL L + +L
Sbjct: 210 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269
Query: 115 NLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLE 174
+++ S+ L ++ N+L + +++ W EEK+ + +K + ++ + +
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 329
Query: 175 IQTEKNKQKIDLDSMENSERIKIIRQNLQM 204
I+ ++ K + + M E K+ RQ M
Sbjct: 330 IREQEEKMRRQEEMMWEKEE-KMRRQEEMM 358
Score = 38.1 bits (87), Expect = 0.007
Identities = 40/198 (20%), Positives = 95/198 (47%), Gaps = 13/198 (6%)
Query: 1 MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSM 60
M EQ ++++ +E + R Q A+ E+++ + ++++ E +
Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR-------EQEEKIREQEKK 438
Query: 61 VDASEEKTPEQI-MQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKI 119
+ EEK EQ ++E++ + E++ + E+++ EI + ++M ++K EK+
Sbjct: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK-EKMHEQEKIRKQEEKV 497
Query: 120 SRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKK---RLQLKQASESKLLEIQ 176
RQ + D + + E + + + +++ + EEK+ + +K + ++ Q E K+ E Q
Sbjct: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE-Q 556
Query: 177 TEKNKQKIDLDSMENSER 194
EK +++ + E R
Sbjct: 557 EEKMQEQEKMRRQEEKIR 574
Score = 36.2 bits (82), Expect = 0.027
Identities = 35/157 (22%), Positives = 70/157 (44%), Gaps = 3/157 (1%)
Query: 27 QVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLE 86
Q A+ + L RL Q ++++ + + EEK EQ + ++ E KI + E
Sbjct: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
Query: 87 NEIEEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQE 146
++ + K+ + R K+ EK+ R ++ + + + EL + M Q++
Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKE--EKMRRLEEMMWEKEEKIRELEEK-MHEQEK 391
Query: 147 SWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQK 183
+ EEK + K R Q K+ + + Q EK +++
Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 428
Score = 36.2 bits (82), Expect = 0.027
Identities = 40/167 (23%), Positives = 80/167 (47%), Gaps = 17/167 (10%)
Query: 51 KQQLLEYKSMVDASEEKTPEQIMQEKQIEAKI---EDLENEIEEVKVAFEIKKLALDRMR 107
++++ E + + EEK EQ + ++ E KI E++ E EE E K ++MR
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
Query: 108 LSTA-LKKNLEKISRQSSVLMDNMKHLLELNKLI------MKSQQES-WDLEEKLLDIRK 159
+++ EKI Q + + + + E + I M+ Q+E W+ EEK+ + +
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 160 KRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEI 206
K Q E K+ + + +Q++ L E E+++ +++L+ I
Sbjct: 628 K----MQEQEEKMRRQEEKMWEQEVRLRQQE--EKMQEHQEHLEAAI 668
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 43.9 bits (102), Expect = 1e-04
Identities = 35/180 (19%), Positives = 88/180 (48%), Gaps = 18/180 (10%)
Query: 36 SEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVA 95
+E+R L++ + Q + ++ E + EE E +++++E + +L+ +I+++++
Sbjct: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961
Query: 96 FEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWD----LE 151
+ K+ ++ A + ++ ++ + S L + + L K + ++ Q++ D E
Sbjct: 962 --LAKVEKEKH----ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEE 1015
Query: 152 EKLLDIRKKRLQLKQASES--------KLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQ 203
+K+ + K + +L+Q E K L + E+NK+K++ D E I + + Q
Sbjct: 1016 DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQ 1075
Score = 43.9 bits (102), Expect = 1e-04
Identities = 39/157 (24%), Positives = 76/157 (48%), Gaps = 17/157 (10%)
Query: 54 LLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALK 113
L E+K+ + S+ + + + + + ++ L+N EE ALD++
Sbjct: 1454 LAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEE----------ALDQLETVKREN 1503
Query: 114 KNLE-KISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKL 172
KNLE +I+ + + +N K + EL K + + E D++ L + + L+ E+K+
Sbjct: 1504 KNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQ---LALEEAEAALEH-EEAKI 1559
Query: 173 LEIQTE--KNKQKIDLDSMENSERIKIIRQNLQMEIK 207
L IQ E + K +ID E E I+ +++N Q ++
Sbjct: 1560 LRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVE 1596
Score = 42.0 bits (97), Expect = 5e-04
Identities = 45/183 (24%), Positives = 95/183 (51%), Gaps = 23/183 (12%)
Query: 37 EDRMTLLLRLRAQTKQQL-LEYKSMVDASEEKTPEQIMQEKQIEAKIEDL---ENEIEEV 92
E+++ L++ + + Q+ E ++++DA EE+ + I + Q+EAKI+++ + EE+
Sbjct: 875 EEKLVTLVQEKNDLQLQVQAESENLLDA-EERCDQLIKAKFQLEAKIKEVTERAEDEEEI 933
Query: 93 KVAFEIKKLALDRMRLSTALKKNLE-------KISRQSSVLMDNMKHLLE----LNKLIM 141
KK L+ + LKK+++ K+ ++ + +K+L E L++ I
Sbjct: 934 NAELTAKKRKLEDE--CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIA 991
Query: 142 KSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENS-ERIKIIRQ 200
K +E L+E ++ L QA E K+ + K+K + ++ +E+S E+ K +R
Sbjct: 992 KLTREKKALQE----AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRV 1047
Query: 201 NLQ 203
+L+
Sbjct: 1048 DLE 1050
Score = 38.9 bits (89), Expect = 0.004
Identities = 36/140 (25%), Positives = 75/140 (53%), Gaps = 14/140 (10%)
Query: 61 VDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKIS 120
+ A E+K + ++E ++EDLE+ +E+ KKL +D R L+ +L K++
Sbjct: 1011 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQE------KKLRVDLERNKRKLEGDL-KLA 1063
Query: 121 RQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKN 180
++S + ++N K +L++ + K E L+ K+ D ++ L L+ + K L+ + E+
Sbjct: 1064 QESILDLENDKQ--QLDERLKKKDFEYCQLQSKVED--EQTLGLQFQKKIKELQARIEEL 1119
Query: 181 KQKIDLDSMENSERIKIIRQ 200
+++I+ E + R K +Q
Sbjct: 1120 EEEIE---AERATRAKTEKQ 1136
Score = 38.5 bits (88), Expect = 0.005
Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 22/176 (12%)
Query: 32 QAACSEDRMTL--LLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI 89
QA E R TL R R +Q+LL+ V + I +K++E + L++E+
Sbjct: 1683 QAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEV 1742
Query: 90 EEV-----KVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQ 144
E+ + KK D ++ LKK + +S ++ MK LE + + Q
Sbjct: 1743 EDASRDARNAEEKAKKAITDAAMMAEELKK-----EQDTSAHLERMKKNLE--QTVKDLQ 1795
Query: 145 QESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQ 200
+ E+ L KK++Q K + + LE + E ++K N+E +K +R+
Sbjct: 1796 HRLDEAEQLALKGGKKQIQ-KLETRIRELEFELEGEQKK-------NTESVKGLRK 1843
Score = 37.4 bits (85), Expect = 0.012
Identities = 43/174 (24%), Positives = 83/174 (47%), Gaps = 22/174 (12%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIE-EVKVA 95
ED++ L + +++ +QQ+ + +S ++ QEK++ +E + ++E ++K+A
Sbjct: 1015 EDKVNSLNKTKSKLEQQVEDLESSLE-----------QEKKLRVDLERNKRKLEGDLKLA 1063
Query: 96 FE-IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
E I L D+ +L LKK + + S + D L+ K I + Q +LEE++
Sbjct: 1064 QESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEI 1123
Query: 155 LDIRKKRLQL-KQASE--------SKLLEIQTEKNKQKIDLDSMENSERIKIIR 199
R R + KQ S+ S+ LE +I+L+ +E +K+ R
Sbjct: 1124 EAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRR 1177
Score = 37.0 bits (84), Expect = 0.016
Identities = 43/210 (20%), Positives = 99/210 (47%), Gaps = 21/210 (10%)
Query: 38 DRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFE 97
D++ + R +Q++ + + + + E KQIE + D++ +EE + A E
Sbjct: 1494 DQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALE 1553
Query: 98 IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDI 157
++ + R++L K+ +I R+ + + ++ L + +++ Q + D E +
Sbjct: 1554 HEEAKILRIQLELTQVKS--EIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVR---S 1608
Query: 158 RKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHVFQ 217
R + ++LK+ E L EI+ + + + + +E +K +R ++Q ++K T
Sbjct: 1609 RNEAIRLKKKMEGDLNEIEIQ-----LSHANRQAAETLKHLR-SVQGQLKDT-------- 1654
Query: 218 NLILGSKVNWAEDPALKEIVLQLEKNVDMM 247
L L + ED LKE + +E+ +++
Sbjct: 1655 QLHLDDALRGQED--LKEQLAIVERRANLL 1682
Score = 35.4 bits (80), Expect = 0.046
Identities = 45/183 (24%), Positives = 87/183 (47%), Gaps = 28/183 (15%)
Query: 31 AQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQ-----IEAKIEDL 85
A+AA + +L + + +L + KS +D + E+I Q K+ +E L
Sbjct: 1548 AEAALEHEEAKIL-----RIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSAL 1602
Query: 86 ENEIEEVKVAFEIKK-----LALDRMRLSTALKKNLEKISRQSSV---LMDNMKHLLELN 137
+ E+ A +KK L ++LS A ++ E + SV L D HL +
Sbjct: 1603 DAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDA- 1661
Query: 138 KLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEI--QTEKNKQKIDLDSMENSERI 195
++ Q+ DL+E+L I ++R L QA +L QTE+ ++ + + ++++ER+
Sbjct: 1662 ---LRGQE---DLKEQLA-IVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 1714
Query: 196 KII 198
+++
Sbjct: 1715 QLL 1717
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 43.9 bits (102), Expect = 1e-04
Identities = 49/182 (26%), Positives = 94/182 (51%), Gaps = 21/182 (11%)
Query: 37 EDRMTLLLRLRAQTKQQL-LEYKSMVDASEEKTPEQIMQEKQIEAKIEDL---ENEIEEV 92
E++M LL+ + + Q+ E + + DA EE+ + I + Q+EAKI+++ + EE+
Sbjct: 880 EEKMVTLLKEKNDLQLQVQAEAEGLADA-EERCDQLIKTKIQLEAKIKEVTERAEDEEEI 938
Query: 93 KVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEE 152
KK L+ + LKK+++ + + ++ KH E NK + +E L+E
Sbjct: 939 NAELTAKKRKLEDE--CSELKKDIDDL-ELTLAKVEKEKHATE-NK-VKNLTEEMAGLDE 993
Query: 153 KLLDIRKKRLQLKQASESKLLEIQTEKN------KQKIDL----DSMENS-ERIKIIRQN 201
+ + K++ L++A + L ++Q E++ K KI L D +E S E+ K +R +
Sbjct: 994 TIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMD 1053
Query: 202 LQ 203
L+
Sbjct: 1054 LE 1055
Score = 40.0 bits (92), Expect = 0.002
Identities = 41/185 (22%), Positives = 87/185 (47%), Gaps = 26/185 (14%)
Query: 37 EDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIE-EVKVA 95
ED++ L + + + +QQ+ + + ++ QEK++ +E + ++E ++K+A
Sbjct: 1020 EDKVNTLTKAKIKLEQQVDDLEGSLE-----------QEKKLRMDLERAKRKLEGDLKLA 1068
Query: 96 FE-IKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKL 154
E I + ++ +L LKK +IS S + D ++L K I + Q +LEE+
Sbjct: 1069 QESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEE- 1127
Query: 155 LDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQH 214
++ ++AS +K EK + + + E SER++ +I++ +
Sbjct: 1128 -------IEAERASRAK-----AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175
Query: 215 VFQNL 219
FQ +
Sbjct: 1176 EFQKM 1180
Score = 38.1 bits (87), Expect = 0.007
Identities = 42/196 (21%), Positives = 87/196 (44%), Gaps = 22/196 (11%)
Query: 32 QAACSEDRMTL--LLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEI 89
QA E R TL R R +Q+LL+ V + I +K++E I ++ E+
Sbjct: 1688 QAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEM 1747
Query: 90 EEV-----KVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQ 144
E++ + KK D ++ LKK + +S ++ MK +E + + Q
Sbjct: 1748 EDILQEARNAEEKAKKAITDAAMMAEELKK-----EQDTSAHLERMKKNME--QTVKDLQ 1800
Query: 145 QESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQM 204
+ E+ L KK++Q LE + + + +++ + N+E +K +R++ +
Sbjct: 1801 LRLDEAEQLALKGGKKQIQ--------KLEARVRELEGEVESEQKRNAEAVKGLRKHERR 1852
Query: 205 EIKITTVIQHVFQNLI 220
++T + +N++
Sbjct: 1853 VKELTYQTEEDRKNIL 1868
Score = 35.4 bits (80), Expect = 0.046
Identities = 32/172 (18%), Positives = 82/172 (47%), Gaps = 6/172 (3%)
Query: 36 SEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVA 95
S D++ L R +Q++ + + ++ E +KQ+E + +L+ +EE + +
Sbjct: 1497 SLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEAS 1556
Query: 96 FEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLL 155
E ++ + +R+ L + ++ R+ + + + L + I++S Q + D E +
Sbjct: 1557 LEHEEGKI--LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAE---I 1611
Query: 156 DIRKKRLQLKQASESKLLEIQTEKN-KQKIDLDSMENSERIKIIRQNLQMEI 206
R ++LK+ E L E++ + N ++ +++ N + I ++ Q+ +
Sbjct: 1612 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHL 1663
Score = 33.5 bits (75), Expect = 0.18
Identities = 47/188 (25%), Positives = 86/188 (45%), Gaps = 33/188 (17%)
Query: 32 QAACSEDRMTL------LLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQ-----IEA 80
QAA E +L +LR++ + Q KS VD + E+I Q K+ +E+
Sbjct: 1547 QAALEEAEASLEHEEGKILRIQLELNQ----VKSEVDRKIAEKDEEIDQLKRNHIRIVES 1602
Query: 81 KIEDLENEIEEVKVAFEIKKLA---LDRMRL-----STALKKNLEKISRQSSVLMDNMKH 132
L+ EI A +KK L+ M + + + L +L D H
Sbjct: 1603 MQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIH 1662
Query: 133 LLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEI--QTEKNKQKIDLDSME 190
L + ++SQ+ DL+E+L + ++R L QA +L QTE++++ + + ++
Sbjct: 1663 LDDA----LRSQE---DLKEQLAMV-ERRANLLQAEIEELRATLEQTERSRKIAEQELLD 1714
Query: 191 NSERIKII 198
SER++++
Sbjct: 1715 ASERVQLL 1722
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.328
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,240,997
Number of Sequences: 37866
Number of extensions: 334622
Number of successful extensions: 3966
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 587
Number of HSP's that attempted gapping in prelim test: 2661
Number of HSP's gapped (non-prelim): 1569
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.