Search of human proteins with 42544134

Search of human proteins with 42544134

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
         (438 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s...   912   0.0  
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s...   849   0.0  
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H...   484   e-137
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho...   481   e-136
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H...   399   e-111
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H...   396   e-110
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [...   394   e-110
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [...   394   e-110
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC...   394   e-110
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC...   394   e-110
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...   355   3e-98
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo...   104   2e-22
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso...   100   2e-21
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom...    88   1e-17
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom...    75   2e-13
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]        67   2e-11
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]        67   2e-11
gi|62865631 solute carrier family 27 (fatty acid transporter), m...    54   4e-07
gi|13325055 solute carrier family 27 (fatty acid transporter), m...    54   4e-07
gi|38524616 solute carrier family 27, member 1 [Homo sapiens]          44   2e-04
gi|227499619 solute carrier family 27 (fatty acid transporter), ...    44   2e-04
gi|40807357 solute carrier family 27 (fatty acid transporter), m...    43   5e-04
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]           40   0.003
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]        39   0.009
gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sap...    36   0.060
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo...    36   0.079
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo...    36   0.079
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]     35   0.13 
gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]     35   0.18 
gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]      35   0.18 

>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
           sapiens]
          Length = 438

 Score =  912 bits (2356), Expect = 0.0
 Identities = 438/438 (100%), Positives = 438/438 (100%)

Query: 1   MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF 60
           MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
Sbjct: 1   MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF 60

Query: 61  AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG 120
           AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
Sbjct: 61  AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG 120

Query: 121 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA 180
           DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
Sbjct: 121 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA 180

Query: 181 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG 240
           VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
Sbjct: 181 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG 240

Query: 241 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT 300
           YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
Sbjct: 241 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT 300

Query: 301 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV 360
           HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
Sbjct: 301 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV 360

Query: 361 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMFNN 420
           TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMFNN
Sbjct: 361 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRRMFNN 420

Query: 421 PICTLPTYRLPPYKLSLL 438
           PICTLPTYRLPPYKLSLL
Sbjct: 421 PICTLPTYRLPPYKLSLL 438


>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
           sapiens]
          Length = 586

 Score =  849 bits (2194), Expect = 0.0
 Identities = 408/409 (99%), Positives = 409/409 (100%)

Query: 1   MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF 60
           MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
Sbjct: 1   MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF 60

Query: 61  AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG 120
           AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
Sbjct: 61  AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG 120

Query: 121 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA 180
           DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
Sbjct: 121 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA 180

Query: 181 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG 240
           VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
Sbjct: 181 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG 240

Query: 241 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT 300
           YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
Sbjct: 241 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT 300

Query: 301 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV 360
           HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
Sbjct: 301 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV 360

Query: 361 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
           TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVK+
Sbjct: 361 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKI 409


>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
           sapiens]
          Length = 580

 Score =  484 bits (1246), Expect = e-137
 Identities = 215/384 (55%), Positives = 294/384 (76%), Gaps = 1/384 (0%)

Query: 26  RALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWW 85
           R LHKD++  TP   +++E++ +  +  +P+ FNFA DVLDQW+ KEK G++P+NPA WW
Sbjct: 21  RRLHKDHQLWTPLTLADFEAINRCNR-PLPKNFNFAADVLDQWSQKEKTGERPANPALWW 79

Query: 86  INRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGT 145
           +N  G+E++WSF ELGSLSRK AN+L++ C LQRGDR+ +ILPR+PEWWL NVAC+RTG 
Sbjct: 80  VNGKGDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGI 139

Query: 146 VLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAVASKCENLHSKLIVSENSREGW 205
           + +PGT QLT KDILYRL++SKA CI+ ++ +APAV+++  +C +L +KL+VS  S  GW
Sbjct: 140 IFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGW 199

Query: 206 GNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLD 265
            + +EL + AS+ H+CV+T   E M I+FTSGT+G+PKM  H+ SS G+G ++ GR+WLD
Sbjct: 200 LSFQELFQFASEEHSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLD 259

Query: 266 LTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCS 325
           L  SD++WN SDTGW K+A  SVFS W+ GACVF H + +F+  + L TL+ YPIT  CS
Sbjct: 260 LKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCS 319

Query: 326 APTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLIC 385
            PTVYRMLVQ D+  YKFKSL+HC++ GEP+ P+V E+WR +TGL++YEGYGQTE  +IC
Sbjct: 320 PPTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMIC 379

Query: 386 GNFKGMKIKPGSMGKPSPAFDVKV 409
            N KG +IKPGSMGK    +DV++
Sbjct: 380 ANQKGQEIKPGSMGKGMLPYDVQI 403


>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
           sapiens]
          Length = 579

 Score =  481 bits (1239), Expect = e-136
 Identities = 211/356 (59%), Positives = 283/356 (79%), Gaps = 1/356 (0%)

Query: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
           +PEYFNFA DVLD W+  E+AG +P NPAFWW+N  G E++WSFEELG  SRK AN+L  
Sbjct: 49  VPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGG 108

Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
           AC LQ GDR++L+LPR+PEWWL +VAC+RTGTV+IPG TQLT+KD+ YRLQ+S+A  IIT
Sbjct: 109 ACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIIT 168

Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
           +D LAP VDA++++C +L +KL+VS++SR GW N +EL++ AS  H C++TK  + +AI+
Sbjct: 169 SDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIY 228

Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
           FTSGT+G PKM  H+ SS+GLG   +GR W+ LT SD+ WNT+DTGW K+AW ++FS W 
Sbjct: 229 FTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAW-TLFSAWP 287

Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
            G+C+F H LPR +   IL TLSK+PIT  C  PT++R+LVQ D+T Y+F+SL+HC++ G
Sbjct: 288 NGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGG 347

Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
           E + PDV EKW+++TG+++YEGYGQ+ETV+IC N KGMKIK GSMGK SP +DV++
Sbjct: 348 EALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQI 403


>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
           sapiens]
          Length = 577

 Score =  399 bits (1026), Expect = e-111
 Identities = 189/356 (53%), Positives = 240/356 (67%), Gaps = 1/356 (0%)

Query: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
           +P  FNFA DVLD W D EKAGK+  +PA WW+N  G+E+ W+F EL   S++ AN+LS 
Sbjct: 40  VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSG 99

Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
           AC LQRGDRV ++LPRVPEWWL  + C+R G + +PGT Q+   DILYRLQ SKA  I+ 
Sbjct: 100 ACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159

Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
            D +   VD VAS+C +L  KL+VSE S +GW N K+L+  AS +H CV+T   E  AI+
Sbjct: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219

Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
           FTSGTSG PKM  H++SS GL   ++   W  L  SD+MW  SDTGW  +   S+  PW 
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILCSLMEPWA 278

Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
            GAC F H LP+F+P  IL+TLS YPI     AP VYRML+Q D++SYKF  L++CV+ G
Sbjct: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVG 338

Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
           E + P+  E WR +TGLDI E YGQTET L C   K MKIKPG MG  +  +DV++
Sbjct: 339 ESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQI 394


>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
           sapiens]
          Length = 577

 Score =  396 bits (1017), Expect = e-110
 Identities = 187/359 (52%), Positives = 247/359 (68%), Gaps = 6/359 (1%)

Query: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
           +PE FNFA  VLD W  KEK GK+  NPAFWW+N  G+E++WSF E+G L+R+ AN+ ++
Sbjct: 45  VPEEFNFASYVLDYWAQKEKEGKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQ 104

Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
            C LQ+GD + L+LPRVPEWWL  V C+RTG + IP T  L  KDILYRLQ SKA  I+T
Sbjct: 105 TCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVT 164

Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
            D LA  VD++AS+C +L +KL+VS++SREGW + + L+K AS  HTCVK+K  + M IF
Sbjct: 165 IDALASEVDSIASQCPSLKTKLLVSDHSREGWLDFRSLVKSASPEHTCVKSKTLDPMVIF 224

Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVN---GRFWLDLTPSDVMWNTSDTGWAKSAWSSVFS 290
           FTSGT+G+PKM  H+H   GL L  +    R    L  SDV W  SD+GW  +   ++  
Sbjct: 225 FTSGTTGFPKMAKHSH---GLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVE 281

Query: 291 PWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCV 350
           PW  G  VF HHLP+F+   I+QTL KYPI  F    ++YRM++Q D TS +F +L+HC 
Sbjct: 282 PWTAGCTVFIHHLPQFDTKVIIQTLLKYPINHFWGVSSIYRMILQQDFTSIRFPALEHCY 341

Query: 351 SAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
           + GE + P   E+W+ +TGL +YE YGQ+ET LIC  + GMKIKPG MGK +P +DV+V
Sbjct: 342 TGGEVVLPKDQEEWKRRTGLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQV 400


>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score =  394 bits (1013), Expect = e-110
 Identities = 189/356 (53%), Positives = 239/356 (67%), Gaps = 1/356 (0%)

Query: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
           +P  FNFA DVLD W D EKAGK+  +PA WW+N  G+E+ W+F EL   S++ ANILS 
Sbjct: 40  VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANILSG 99

Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
           AC LQRGDRV ++LPRVPEWWL  + C+R G + +PGT Q+   DILYRLQ SKA  I+ 
Sbjct: 100 ACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159

Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
            D +   VD VAS+C +L  KL+VSE S +GW N K+L+  AS +H CV+T   E  AI+
Sbjct: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219

Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
           FTSGTSG PKM  H++SS GL   ++   W  L  SD+MW  SDTGW  +   S+   W 
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILGSLLESWT 278

Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
            GAC F H LP+F+P  IL+TLS YPI     AP VYRML+Q D++SYKF  L++C++ G
Sbjct: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGG 338

Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
           E + P+  E WR +TGLDI E YGQTET L C   K MKIKPG MG  +  +DV+V
Sbjct: 339 ESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394


>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score =  394 bits (1013), Expect = e-110
 Identities = 189/356 (53%), Positives = 239/356 (67%), Gaps = 1/356 (0%)

Query: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
           +P  FNFA DVLD W D EKAGK+  +PA WW+N  G+E+ W+F EL   S++ ANILS 
Sbjct: 40  VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANILSG 99

Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
           AC LQRGDRV ++LPRVPEWWL  + C+R G + +PGT Q+   DILYRLQ SKA  I+ 
Sbjct: 100 ACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159

Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
            D +   VD VAS+C +L  KL+VSE S +GW N K+L+  AS +H CV+T   E  AI+
Sbjct: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219

Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
           FTSGTSG PKM  H++SS GL   ++   W  L  SD+MW  SDTGW  +   S+   W 
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILGSLLESWT 278

Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
            GAC F H LP+F+P  IL+TLS YPI     AP VYRML+Q D++SYKF  L++C++ G
Sbjct: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGG 338

Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
           E + P+  E WR +TGLDI E YGQTET L C   K MKIKPG MG  +  +DV+V
Sbjct: 339 ESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394


>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 2 [Homo sapiens]
          Length = 571

 Score =  394 bits (1012), Expect = e-110
 Identities = 188/356 (52%), Positives = 239/356 (67%), Gaps = 1/356 (0%)

Query: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
           +P  FNFA DVLD W D EKAGK+  +PA WW+N  G+E+ W+F EL   S++ AN+LS 
Sbjct: 40  VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSG 99

Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
           AC LQRGDRV ++LPRVPEWWL  + C+R G + +PGT Q+   DILYRLQ SKA  I+ 
Sbjct: 100 ACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159

Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
            D +   VD VAS+C +L  KL+VSE S +GW N K+L+  AS +H CV+T   E  AI+
Sbjct: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219

Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
           FTSGTSG PKM  H++SS GL   ++   W  L  SD+MW  SDTGW  +   S+   W 
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILGSLLESWT 278

Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
            GAC F H LP+F+P  IL+TLS YPI     AP VYRML+Q D++SYKF  L++C++ G
Sbjct: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGG 338

Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
           E + P+  E WR +TGLDI E YGQTET L C   K MKIKPG MG  +  +DV+V
Sbjct: 339 ESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394


>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 1 [Homo sapiens]
          Length = 571

 Score =  394 bits (1012), Expect = e-110
 Identities = 188/356 (52%), Positives = 239/356 (67%), Gaps = 1/356 (0%)

Query: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
           +P  FNFA DVLD W D EKAGK+  +PA WW+N  G+E+ W+F EL   S++ AN+LS 
Sbjct: 40  VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSG 99

Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
           AC LQRGDRV ++LPRVPEWWL  + C+R G + +PGT Q+   DILYRLQ SKA  I+ 
Sbjct: 100 ACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159

Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
            D +   VD VAS+C +L  KL+VSE S +GW N K+L+  AS +H CV+T   E  AI+
Sbjct: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219

Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
           FTSGTSG PKM  H++SS GL   ++   W  L  SD+MW  SDTGW  +   S+   W 
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILGSLLESWT 278

Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
            GAC F H LP+F+P  IL+TLS YPI     AP VYRML+Q D++SYKF  L++C++ G
Sbjct: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGG 338

Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
           E + P+  E WR +TGLDI E YGQTET L C   K MKIKPG MG  +  +DV+V
Sbjct: 339 ESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
           sapiens]
          Length = 480

 Score =  355 bits (912), Expect = 3e-98
 Identities = 169/357 (47%), Positives = 238/357 (66%), Gaps = 1/357 (0%)

Query: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
           + + FNFAKDVLDQW+  EK G +   PA W ++  GEE +WSFE +  LS+K A+ILS+
Sbjct: 45  VSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSD 104

Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
            C+L  GDR+++ILP  PE +   +AC+R G   +PG+ QLT K I Y+L+ SKA CI+ 
Sbjct: 105 TCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVA 164

Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
           N+ +AP V++  S C  L +KL+VS+ S +GW + K+L++ A    T ++TK  + MAIF
Sbjct: 165 NEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIF 224

Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
           FT GT+G PKM  ++    G+G S   R W+DL P+DV+W+  D      + S+V   W 
Sbjct: 225 FTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWF 284

Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQND-ITSYKFKSLKHCVSA 352
           QGACVF  H+P F P ++L  LS++PIT   + P +Y+ L+Q+   TSY+FKSLK CV+A
Sbjct: 285 QGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAA 344

Query: 353 GEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
           G PI+P V E W+  T LDIYEGYGQTET L+C   K +K+KP S+GKP P + V++
Sbjct: 345 GGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQI 401


>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
           1 [Homo sapiens]
          Length = 701

 Score =  104 bits (259), Expect = 2e-22
 Identities = 95/373 (25%), Positives = 158/373 (42%), Gaps = 54/373 (14%)

Query: 59  NFAKDVLDQWTDKEKAGKKPSNPAFWWI-NRNGEEMRWSFEELGSLSRKFANILSEACSL 117
           N   +VLD+   ++K G K    AF+W  N  GE  + ++ +L     +F+N+L +   +
Sbjct: 102 NICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GI 157

Query: 118 QRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDV- 176
           Q+GDRV + +P +PE  +A +AC R G +        + + +  R+  S  + +IT D  
Sbjct: 158 QKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF 217

Query: 177 --------LAPAVDAVASKCEN----LHSKLIVSENSRE--GWGNLK------------- 209
                   L    D    KC+     +   ++V    R   G G+               
Sbjct: 218 YRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277

Query: 210 -------------ELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGL 256
                        ELM+ A D          + + I +TSG++G PK   HT   + L +
Sbjct: 278 QISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYV 337

Query: 257 SVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTL 315
           +   ++  D    DV W T+D GW        + P   GA  V    +P +   + L ++
Sbjct: 338 ATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSI 397

Query: 316 -SKYPITVFCSAPTVYRMLVQ---NDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLD 371
             KY +T F +APT  R+L++     +T +   SL+   + GEPI P+    +    G  
Sbjct: 398 VDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQ 457

Query: 372 ---IYEGYGQTET 381
              I + + QTET
Sbjct: 458 RCPIVDTFWQTET 470


>gi|253970489 acyl-CoA synthetase short-chain family member 2
           isoform 2 [Homo sapiens]
          Length = 714

 Score =  100 bits (250), Expect = 2e-21
 Identities = 96/386 (24%), Positives = 159/386 (41%), Gaps = 67/386 (17%)

Query: 59  NFAKDVLDQWTDKEKAGKKPSNPAFWWI-NRNGEEMRWSFEELGSLSRKFANILSEACSL 117
           N   +VLD+   ++K G K    AF+W  N  GE  + ++ +L     +F+N+L +   +
Sbjct: 102 NICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GI 157

Query: 118 QRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDV- 176
           Q+GDRV + +P +PE  +A +AC R G +        + + +  R+  S  + +IT D  
Sbjct: 158 QKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF 217

Query: 177 --------LAPAVDAVASKCEN----LHSKLIVSENSR--------------------EG 204
                   L    D    KC+     +   ++V    R                    + 
Sbjct: 218 YRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277

Query: 205 WGNLKE---------------------LMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPK 243
            G LKE                     LM+ A D          + + I +TSG++G PK
Sbjct: 278 QGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPK 337

Query: 244 MTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHH 302
              HT   + L ++   ++  D    DV W T+D GW        + P   GA  V    
Sbjct: 338 GVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEG 397

Query: 303 LPRFEPTSILQTL-SKYPITVFCSAPTVYRMLVQ---NDITSYKFKSLKHCVSAGEPITP 358
           +P +   + L ++  KY +T F +APT  R+L++     +T +   SL+   + GEPI P
Sbjct: 398 IPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINP 457

Query: 359 DVTEKWRNKTGLD---IYEGYGQTET 381
           +    +    G     I + + QTET
Sbjct: 458 EAWLWYHRVVGAQRCPIVDTFWQTET 483


>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
           sapiens]
          Length = 689

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 95/386 (24%), Positives = 159/386 (41%), Gaps = 40/386 (10%)

Query: 49  DFKLGIPEYF-----NFAKDVLDQWTDKEKAGKKPSNPAFWWI-NRNGEEMRWSFEELGS 102
           DF  G   +F     N + + LDQ        K P + A  W  +  G E+R ++ EL  
Sbjct: 94  DFSTGKIGWFLGGQLNVSVNCLDQ-----HVRKSPESVALIWERDEPGTEVRITYRELLE 148

Query: 103 LSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYR 162
            + + AN L     + RGDRV + +P  P    A +AC R G V        + + +  R
Sbjct: 149 TTCRLANTLKRH-GVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGR 207

Query: 163 LQSSKANCIITNDV---------LAPAVDAVASKCENLHSKLIVSE-NSREGWGNLKELM 212
           +  +K   +IT +          L   VD     C  +   L+    +++   G+L   +
Sbjct: 208 INDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPL 267

Query: 213 KH--ASDSHTCVKTK--HNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
           +   A +   C        +++ + +TSG++G PK   HT + + L  ++  +   D  P
Sbjct: 268 EQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQP 327

Query: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTS--ILQTLSKYPITVFCSA 326
            D+    +D GW       V+ P   GA           P +    +T+ +  I  F  A
Sbjct: 328 GDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGA 387

Query: 327 PTVYRMLVQND---ITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLD----IYEGYGQT 379
           PT  R+L++     +  Y   SL+   S GEPI  +  E W ++   D    + + + QT
Sbjct: 388 PTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINCEAWE-WLHRVVGDSRCTLVDTWWQT 446

Query: 380 ETVLIC----GNFKGMKIKPGSMGKP 401
           ET  IC     + +G +I P    +P
Sbjct: 447 ETGGICIAPRPSEEGAEILPAMAMRP 472


>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
           sapiens]
          Length = 686

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 82/373 (21%), Positives = 141/373 (37%), Gaps = 41/373 (10%)

Query: 95  WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
           ++++E+     K A +L +   +++GD V++ +P +P+     +AC R G +        
Sbjct: 144 FTYKEVLEQVSKLAGVLVKH-GIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGF 202

Query: 155 TQKDILYRLQSSKANCIITNDV---------LAPAVDAVASKCENLHSKLIVSENSREGW 205
             K++  R+   K   ++T              P V+      ++   K+++        
Sbjct: 203 ASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEA 262

Query: 206 GNL---------KELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGL 256
             L         +E+ K  + SH CV       + I +TSGT+G PK        + + L
Sbjct: 263 VPLAPGRDLDWDEEMAK--AQSHDCVPVLSEHPLYILYTSGTTGLPKGVIRPTGGYAVML 320

Query: 257 SVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQG-ACVFTHHLPRFEPT--SILQ 313
             +      L P +V W  SD GW        + P + G   V     P   P   +  +
Sbjct: 321 HWSMSSIYGLQPGEVWWAASDLGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYFR 380

Query: 314 TLSKYPITVFCSAPTVYRMLVQNDI-----TSYKFKSLKHCVSAGEPITPDVTEKWRNKT 368
            L+++ +    +APT  R + Q D        Y     K    AGE    +  E  +N  
Sbjct: 381 VLAEHGVAALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTLFVAGERCDVETLEWSKNVF 440

Query: 369 GLDIYEGYGQTET----VLICGNFKGMKI-KPGSMGKPSPAFDVKVCTSPSR----RMFN 419
            + + + + QTET       C      K   PG  GK  P ++V +     +    R   
Sbjct: 441 RVPVLDHWWQTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLKARCLG 500

Query: 420 NPICTLPTYRLPP 432
           N +  LP   LPP
Sbjct: 501 NIVVKLP---LPP 510


>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 76/348 (21%), Positives = 140/348 (40%), Gaps = 41/348 (11%)

Query: 94  RWSFEELGSLSRKFANILSEACSLQRGD----RVILILPRVPEWWLANVACLRTGTVLIP 149
           R ++ EL S S + +  +   C    GD    RV  +      + +A  A   +G V +P
Sbjct: 65  RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVP 124

Query: 150 GTTQLTQKDILYRLQSSKANCIITN----DVLAPAVDAVASKCENLHSKLIVSENSREGW 205
              +     + Y +  S+++ ++ +    ++L+P V  +      L   +          
Sbjct: 125 LYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGA------ 178

Query: 206 GNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLD 265
                 ++  ++     +   N+   I +TSGT+G PK    TH +    ++     W  
Sbjct: 179 ------VEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWA- 231

Query: 266 LTPSDVMWNTSDTGWAKSAWSSVFSP-WIQGACVFTHHLPRFEPTSILQTL--SKYP-IT 321
            T  DV+ +           +++  P W+   CV    +P F P  + +    S+ P I 
Sbjct: 232 WTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVM---MPEFSPQQVWEKFLSSETPRIN 288

Query: 322 VFCSAPTVYRMLV------------QNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG 369
           VF + PT+Y  L+            Q+ + +   + ++  VS    +   V EKW+N TG
Sbjct: 289 VFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITG 348

Query: 370 LDIYEGYGQTET-VLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRR 416
             + E YG TE  + + G        PGS+G P P   V++ +   +R
Sbjct: 349 HTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQR 396


>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 76/348 (21%), Positives = 140/348 (40%), Gaps = 41/348 (11%)

Query: 94  RWSFEELGSLSRKFANILSEACSLQRGD----RVILILPRVPEWWLANVACLRTGTVLIP 149
           R ++ EL S S + +  +   C    GD    RV  +      + +A  A   +G V +P
Sbjct: 65  RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVP 124

Query: 150 GTTQLTQKDILYRLQSSKANCIITN----DVLAPAVDAVASKCENLHSKLIVSENSREGW 205
              +     + Y +  S+++ ++ +    ++L+P V  +      L   +          
Sbjct: 125 LYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGA------ 178

Query: 206 GNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLD 265
                 ++  ++     +   N+   I +TSGT+G PK    TH +    ++     W  
Sbjct: 179 ------VEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWA- 231

Query: 266 LTPSDVMWNTSDTGWAKSAWSSVFSP-WIQGACVFTHHLPRFEPTSILQTL--SKYP-IT 321
            T  DV+ +           +++  P W+   CV    +P F P  + +    S+ P I 
Sbjct: 232 WTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVM---MPEFSPQQVWEKFLSSETPRIN 288

Query: 322 VFCSAPTVYRMLV------------QNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG 369
           VF + PT+Y  L+            Q+ + +   + ++  VS    +   V EKW+N TG
Sbjct: 289 VFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITG 348

Query: 370 LDIYEGYGQTET-VLICGNFKGMKIKPGSMGKPSPAFDVKVCTSPSRR 416
             + E YG TE  + + G        PGS+G P P   V++ +   +R
Sbjct: 349 HTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQR 396


>gi|62865631 solute carrier family 27 (fatty acid transporter),
           member 6 [Homo sapiens]
          Length = 619

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 70/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%)

Query: 95  WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
           ++++++   S + A++     SL++GD V L++   P++        + G V+    T +
Sbjct: 80  YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139

Query: 155 TQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMK 213
               +L  +++     ++   D+L    + + S  EN+ S   + ++  +G  +LKE + 
Sbjct: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENI-SVWGMKDSVPQGVISLKEKLS 198

Query: 214 HASD-----SHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
            + D     SH  V    +  + IF TSGT+G PK    +      G +V   F    T 
Sbjct: 199 TSPDEPVPRSHHVVSLLKSTCLYIF-TSGTTGLPKAAVISQLQVLRGSAVLWAF--GCTA 255

Query: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327
            D+++ T     + +A   +      GA CV      +F  +       KY +TVF    
Sbjct: 256 HDIVYITLPLYHSSAAILGISGCVELGATCVLK---KKFSASQFWSDCKKYDVTVFQYIG 312

Query: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICG 386
            + R L +      + K  K  ++ G  I  DV  ++ ++ G + + E Y  TE+ +   
Sbjct: 313 ELCRYLCKQSKREGE-KDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFM 371

Query: 387 NFKGMKIKPGSMGK 400
           N+ G   + G++G+
Sbjct: 372 NYTG---RIGAIGR 382


>gi|13325055 solute carrier family 27 (fatty acid transporter),
           member 6 [Homo sapiens]
          Length = 619

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 70/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%)

Query: 95  WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
           ++++++   S + A++     SL++GD V L++   P++        + G V+    T +
Sbjct: 80  YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139

Query: 155 TQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMK 213
               +L  +++     ++   D+L    + + S  EN+ S   + ++  +G  +LKE + 
Sbjct: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENI-SVWGMKDSVPQGVISLKEKLS 198

Query: 214 HASD-----SHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
            + D     SH  V    +  + IF TSGT+G PK    +      G +V   F    T 
Sbjct: 199 TSPDEPVPRSHHVVSLLKSTCLYIF-TSGTTGLPKAAVISQLQVLRGSAVLWAF--GCTA 255

Query: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327
            D+++ T     + +A   +      GA CV      +F  +       KY +TVF    
Sbjct: 256 HDIVYITLPLYHSSAAILGISGCVELGATCVLK---KKFSASQFWSDCKKYDVTVFQYIG 312

Query: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICG 386
            + R L +      + K  K  ++ G  I  DV  ++ ++ G + + E Y  TE+ +   
Sbjct: 313 ELCRYLCKQSKREGE-KDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFM 371

Query: 387 NFKGMKIKPGSMGK 400
           N+ G   + G++G+
Sbjct: 372 NYTG---RIGAIGR 382


>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
          Length = 646

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 69/312 (22%), Positives = 122/312 (39%), Gaps = 15/312 (4%)

Query: 95  WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
           W+F +L + S   AN+  +      GD V + L   PE+    +   + G         L
Sbjct: 104 WTFAQLDAYSNAVANLFRQL-GFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162

Query: 155 TQKDILYRLQSSKANCIITNDVLAPAVDAVASKCENLHSKLIVSENSREG----WGNLKE 210
            ++ + + L +S A  +I    +  AV  V+        K    +   EG       L  
Sbjct: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222

Query: 211 LMKHASDSHTC-VKTKH-NEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
           L+K AS +    + +K  ++ +   +TSGT+G PK     HS +   ++  G     +  
Sbjct: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRY-YRMAAFGHHAYRMQA 281

Query: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPT 328
           +DV+++      +      V    I G  V      +F  +       KY  TV      
Sbjct: 282 ADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLR--KKFSASRFWDDCIKYNCTVVQYIGE 339

Query: 329 VYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGL-DIYEGYGQTETVLICGN 387
           + R L++  +   + +  +  ++ G  + P + E++  + G+  I E YG TE      N
Sbjct: 340 ICRYLLKQPVREAE-RRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIAN 398

Query: 388 FKGMKIKPGSMG 399
             G   K GS G
Sbjct: 399 MDG---KVGSCG 407


>gi|227499619 solute carrier family 27 (fatty acid transporter),
           member 2 isoform 1 [Homo sapiens]
          Length = 620

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 68/339 (20%), Positives = 137/339 (40%), Gaps = 26/339 (7%)

Query: 72  EKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVP 131
           EKA + P  P   +      +   ++ ++   S + A  L +   L++GD V L++   P
Sbjct: 61  EKARQTPHKPFLLF-----RDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEP 115

Query: 132 EWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAV--ASKCE 189
            +    +  ++ G  +      +  K +L+  Q   A  ++ +  L  AV+ +  + K +
Sbjct: 116 AYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKD 175

Query: 190 NLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIM-----AIFFTSGTSGYPKM 244
           ++    +   ++ +G  +  + +   S +    ++  +E+         +TSGT+G PK 
Sbjct: 176 DVSIYYVSRTSNTDGIDSFLDKVDEVS-TEPIPESWRSEVTFSTPALYIYTSGTTGLPKA 234

Query: 245 TAHTHSS--FGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHH 302
              TH    +G GL+    F   L   DV++ T     + +    +    + GA +    
Sbjct: 235 AMITHQRIWYGTGLT----FVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALR- 289

Query: 303 LPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTE 362
             +F  +       KY +TV      + R L  N       +  K  ++ G  +  DV  
Sbjct: 290 -TKFSASQFWDDCRKYNVTVIQYIGELLRYLC-NSPQKPNDRDHKVRLALGNGLRGDVWR 347

Query: 363 KWRNKTG-LDIYEGYGQTETVLICGNFKGMKIKPGSMGK 400
           ++  + G + IYE Y  TE  +    F     K G++G+
Sbjct: 348 QFVKRFGDICIYEFYAATEGNI---GFMNYARKVGAVGR 383


>gi|40807357 solute carrier family 27 (fatty acid transporter),
           member 4 [Homo sapiens]
          Length = 643

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 46/196 (23%), Positives = 82/196 (41%), Gaps = 19/196 (9%)

Query: 90  GEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEW---WLANVACLRTGTV 146
           G +  W+F +L   S   AN L +A  L  GD   + +    E+   WL  +A L     
Sbjct: 97  GTDTHWTFRQLDEYSSSVANFL-QARGLASGDVAAIFMENRNEFVGLWLG-MAKLGVEAA 154

Query: 147 LIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAVASK--------CENLHSKLIVS 198
           LI   T L +  +L+ L +S+A  ++    +A A+  V +         C        V 
Sbjct: 155 LI--NTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWEPGAVP 212

Query: 199 ENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSV 258
            ++      LK+  KH     +C      + +   +TSGT+G PK     HS +   ++ 
Sbjct: 213 PSTEHLDPLLKDAPKHLP---SCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRY-YRMAA 268

Query: 259 NGRFWLDLTPSDVMWN 274
              +   + P+D++++
Sbjct: 269 LVYYGFRMRPNDIVYD 284


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 73/303 (24%), Positives = 114/303 (37%), Gaps = 29/303 (9%)

Query: 114 ACSLQRGDRVILILPRVPE--WWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCI 171
           A  L  G  V L+LP  PE  W    +A     T  +P  T L +  +L+ L+S  A  +
Sbjct: 208 AAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVP--TALRRGPLLHCLRSCGARAL 265

Query: 172 ITNDVLAPAV------DAVASKCENLHSKLIVSENSREGWGNLKELMKHASDS----HTC 221
               VLAP        D  A +   LH           G  +L   +    D     +  
Sbjct: 266 ----VLAPEFLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLS 321

Query: 222 VKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWL-DLTPSDVMWNTSDTGW 280
                 +     FTSGT+G PK    +H      L   G + L  +   DV++       
Sbjct: 322 SPQSITDTCLYIFTSGTTGLPKAARISHLKI---LQCQGFYQLCGVHQEDVIYLALPLYH 378

Query: 281 AKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITS 340
              +   +      GA V      +F      +   ++ +TVF     + R LV N   S
Sbjct: 379 MSGSLLGIVGCMGIGATVVLK--SKFSAGQFWEDCQQHRVTVFQYIGELCRYLV-NQPPS 435

Query: 341 YKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICGNFKGMKIKPGSMG 399
              +  K  ++ G  + PD  E++  + G L + E YG TE  +   N+ G +   G++G
Sbjct: 436 KAERGHKVRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQR---GAVG 492

Query: 400 KPS 402
           + S
Sbjct: 493 RAS 495


>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
          Length = 615

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 69/319 (21%), Positives = 124/319 (38%), Gaps = 31/319 (9%)

Query: 91  EEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPG 150
           E++R +F +L     K A+ L  +  L +GDR+ +  P    W L  +A  + G +L+  
Sbjct: 96  EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154

Query: 151 TTQLTQKDILYRLQSSKANCII-----TNDVLAPAVDAVASKCENLHSKLIVSENSRE-- 203
                  ++ Y L+      ++             +  +  + EN     + S+   +  
Sbjct: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214

Query: 204 ----------GWGNLKELMKHASDSHTCVKTKHNEIMA-------IFFTSGTSGYPKMTA 246
                     G   L E++   S      + ++N+          I FTSGT+G PK   
Sbjct: 215 TVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274

Query: 247 HTHSSFGLGLSVNG-RFWL-DLTPSDV-MWNTSDTGWAKSAWSSVFSPWIQGACVFTHHL 303
            +H +     ++ G R  L + TP  + M   +       + +      + GA +     
Sbjct: 275 LSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILAS- 333

Query: 304 PRFEPTSILQTLSKYPITVFCSAPTVY-RMLVQNDITSYKFKSLKHCVSAGEPITPDVTE 362
           P F     L+ +S+   T     PT++  +L Q D +SY   ++   V AG P  P++  
Sbjct: 334 PIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPELIR 393

Query: 363 KWRNKTGL-DIYEGYGQTE 380
              NK  + D+   YG TE
Sbjct: 394 AIINKINMKDLVVAYGTTE 412


>gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sapiens]
          Length = 1576

 Score = 36.2 bits (82), Expect = 0.060
 Identities = 37/125 (29%), Positives = 54/125 (43%), Gaps = 12/125 (9%)

Query: 60   FAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEM-RWSFEELGSLSRKFANILSEACSLQ 118
            F  ++L QW    +A   P +  F  +N  G  +   S  +L   + + A++L +   L 
Sbjct: 990  FLAEIL-QW----RAQATPDHVLFMLLNAKGTTVCTASCLQLHKRAERIASVLGDKGHLN 1044

Query: 119  RGDRVILILPRVPEWWLANVACLRTG----TVLIPGTTQLTQKDILYRL--QSSKANCII 172
             GD V+L+ P   E   A   CL  G    TV  P    LT      R+    SKA CI+
Sbjct: 1045 AGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACIL 1104

Query: 173  TNDVL 177
            T+  L
Sbjct: 1105 TSQTL 1109


>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
           b [Homo sapiens]
          Length = 722

 Score = 35.8 bits (81), Expect = 0.079
 Identities = 23/82 (28%), Positives = 35/82 (42%)

Query: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGN 387
           +++  L  N I +     ++  V+   P +P V    R   G  +YEGYGQTE    C  
Sbjct: 435 SIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTF 494

Query: 388 FKGMKIKPGSMGKPSPAFDVKV 409
                   G +G P P   +K+
Sbjct: 495 TTPGDWTSGHVGAPLPCNHIKL 516



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 43/191 (22%), Positives = 73/191 (38%), Gaps = 25/191 (13%)

Query: 76  KKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWL 135
           +KP  P  W    + +E+    E LGS       +L   C       + +     PEW +
Sbjct: 137 RKPKQPYQWL---SYQEVADRAEFLGS------GLLQHNCKACTDQFIGVFAQNRPEWII 187

Query: 136 ANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAV--DAVASKCENLHS 193
             +AC     V++P    L    I Y + ++  + +I +      +  + V  K E    
Sbjct: 188 VELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK-ETPGL 246

Query: 194 KLIV-----SENSREGWGNLKELMKHASDSHTCVKTKH--------NEIMAIFFTSGTSG 240
           KLI+      E  +E       ++K       C +  H        +++  + FTSGT+G
Sbjct: 247 KLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTG 306

Query: 241 YPKMTAHTHSS 251
            PK    TH +
Sbjct: 307 NPKGAMLTHGN 317


>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
           a [Homo sapiens]
          Length = 722

 Score = 35.8 bits (81), Expect = 0.079
 Identities = 23/82 (28%), Positives = 35/82 (42%)

Query: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGN 387
           +++  L  N I +     ++  V+   P +P V    R   G  +YEGYGQTE    C  
Sbjct: 435 SIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTF 494

Query: 388 FKGMKIKPGSMGKPSPAFDVKV 409
                   G +G P P   +K+
Sbjct: 495 TTPGDWTSGHVGAPLPCNHIKL 516



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 43/191 (22%), Positives = 73/191 (38%), Gaps = 25/191 (13%)

Query: 76  KKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWL 135
           +KP  P  W    + +E+    E LGS       +L   C       + +     PEW +
Sbjct: 137 RKPKQPYQWL---SYQEVADRAEFLGS------GLLQHNCKACTDQFIGVFAQNRPEWII 187

Query: 136 ANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAV--DAVASKCENLHS 193
             +AC     V++P    L    I Y + ++  + +I +      +  + V  K E    
Sbjct: 188 VELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK-ETPGL 246

Query: 194 KLIV-----SENSREGWGNLKELMKHASDSHTCVKTKH--------NEIMAIFFTSGTSG 240
           KLI+      E  +E       ++K       C +  H        +++  + FTSGT+G
Sbjct: 247 KLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTG 306

Query: 241 YPKMTAHTHSS 251
            PK    TH +
Sbjct: 307 NPKGAMLTHGN 317


>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
          Length = 1098

 Score = 35.0 bits (79), Expect = 0.13
 Identities = 43/174 (24%), Positives = 74/174 (42%), Gaps = 14/174 (8%)

Query: 216 SDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNT 275
           ++ H  ++ KH  +  +  TSGT+G PK+    H      +  + R   D+T  DV++  
Sbjct: 180 AEEHMDLRLKHC-LAYVLHTSGTTGIPKIVRVPHKCIVPNIQ-HFRVLFDITQEDVLFLA 237

Query: 276 SDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTL-SKYPITVFCSAPTVYR--- 331
           S   +  S      +     + +      +  P+ +   L S + +TV  + PT+ R   
Sbjct: 238 SPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFG 297

Query: 332 -MLVQNDITSYKFKSLKHCVSAGEPI-TPDVTEKWR---NKTGLDIYEGYGQTE 380
             L+++ + S    SL+     GE   +  V   WR   NKT   I+  YG TE
Sbjct: 298 SQLIKSTVLS-ATTSLRVLALGGEAFPSLTVLRSWRGEGNKT--QIFNVYGITE 348


>gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]
          Length = 1567

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 38/130 (29%), Positives = 54/130 (41%), Gaps = 18/130 (13%)

Query: 58   FNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSF-EELGSLSRKFANILSEACS 116
            F F  DVL QW    +A   P +P F  +N  G     +   +L   + + A  L E   
Sbjct: 980  FLFLADVL-QW----RAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEKGR 1034

Query: 117  LQRGDRVILILPRVPEWWLANVACLRTGTVLIP---------GTTQLTQKDILYRLQSSK 167
            L  GD V L+ P   +   A   CL  G V +          GTT  T K I   ++ SK
Sbjct: 1035 LSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMI---VEVSK 1091

Query: 168  ANCIITNDVL 177
            + C++T   +
Sbjct: 1092 SACVLTTQAV 1101


>gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]
          Length = 1571

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 38/130 (29%), Positives = 54/130 (41%), Gaps = 18/130 (13%)

Query: 58   FNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSF-EELGSLSRKFANILSEACS 116
            F F  DVL QW    +A   P +P F  +N  G     +   +L   + + A  L E   
Sbjct: 984  FLFLADVL-QW----RAHTTPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEKGR 1038

Query: 117  LQRGDRVILILPRVPEWWLANVACLRTGTVLIP---------GTTQLTQKDILYRLQSSK 167
            L  GD V L+ P   +   A   CL  G V +          GTT  T K I   ++ SK
Sbjct: 1039 LSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMI---VEVSK 1095

Query: 168  ANCIITNDVL 177
            + C++T   +
Sbjct: 1096 SACVLTTQAV 1105


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,685,697
Number of Sequences: 37866
Number of extensions: 813999
Number of successful extensions: 1645
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 1592
Number of HSP's gapped (non-prelim): 57
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.