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Search of human proteins with 42544125
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
(638 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 1366 0.0
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 1273 0.0
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] 1122 0.0
gi|160707881 formin 2 [Homo sapiens] 115 1e-25
gi|42544127 splicing factor 1 isoform 4 [Homo sapiens] 112 8e-25
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 112 8e-25
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 112 1e-24
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 107 3e-23
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 107 3e-23
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 107 3e-23
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 105 1e-22
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 105 1e-22
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 103 4e-22
gi|163965366 nascent polypeptide-associated complex alpha subuni... 102 1e-21
gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7... 100 5e-21
gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7... 100 5e-21
gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6... 100 5e-21
gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5... 100 5e-21
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 99 1e-20
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 99 1e-20
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 99 2e-20
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 98 2e-20
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 97 3e-20
gi|18959210 WIRE protein [Homo sapiens] 95 2e-19
gi|11386183 WAS protein family, member 2 [Homo sapiens] 92 2e-18
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 92 2e-18
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 91 3e-18
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 91 3e-18
gi|47132519 Ras association and pleckstrin homology domains 1 is... 89 1e-17
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 87 4e-17
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 1366 bits (3535), Expect = 0.0
Identities = 638/638 (100%), Positives = 638/638 (100%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
Query: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN
Sbjct: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
Query: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK
Sbjct: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
Query: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR
Sbjct: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
Query: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP
Sbjct: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS
Sbjct: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
Query: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP
Sbjct: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
Query: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
Query: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPR 600
IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPR
Sbjct: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPR 600
Query: 601 GGDGPSHESEDFPRPLVTLPGRQPQQRPWWTGWFGKAA 638
GGDGPSHESEDFPRPLVTLPGRQPQQRPWWTGWFGKAA
Sbjct: 601 GGDGPSHESEDFPRPLVTLPGRQPQQRPWWTGWFGKAA 638
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 1273 bits (3294), Expect = 0.0
Identities = 599/612 (97%), Positives = 601/612 (98%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
Query: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN
Sbjct: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
Query: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK
Sbjct: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
Query: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR
Sbjct: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
Query: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP
Sbjct: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS
Sbjct: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
Query: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP
Sbjct: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
Query: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
Query: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPR 600
IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMM P
Sbjct: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPP 600
Query: 601 GGDGPSHESEDF 612
P + +F
Sbjct: 601 PPPPPPMDPSNF 612
Score = 65.1 bits (157), Expect = 2e-10
Identities = 58/183 (31%), Positives = 67/183 (36%), Gaps = 43/183 (23%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWM--------NSGPSE 375
P P G P + PL + PPPPS + + PW ++G
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
Query: 376 SRPYHGMHGGGPGGPG-----GGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP 430
P+ PG G P P P G P PPPP PPPP
Sbjct: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLP--------PGVQPPLPPGAPPPP---PPPP 589
Query: 431 PMNQG-----PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP 485
P + G P PP PPPMD T +G GV GM PP GM PP PPPP
Sbjct: 590 PGSAGMMYAPPPPP----PPPMDPSNFVTMMGMGV------AGM---PPFGM-PPAPPPP 635
Query: 486 SGQ 488
Q
Sbjct: 636 PPQ 638
Score = 32.0 bits (71), Expect = 1.8
Identities = 37/143 (25%), Positives = 40/143 (27%), Gaps = 45/143 (31%)
Query: 524 PWQQ-------NTTTTTTSAGTGSIP-------PWQQQQA-----------------AAA 552
PWQ NTT T G G I P Q A A
Sbjct: 264 PWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEA 323
Query: 553 ASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPP--------PPPPGSAGMMIPPRGG-- 602
P + P PL +P P PPPP PP S P G
Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
Query: 603 ----DGPSHESEDFPRPLVTLPG 621
GP FP PL +L G
Sbjct: 384 GGGPGGPGGGPHSFPHPLPSLTG 406
>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
Length = 548
Score = 1122 bits (2903), Expect = 0.0
Identities = 528/536 (98%), Positives = 529/536 (98%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
Query: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN
Sbjct: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
Query: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK
Sbjct: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
Query: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR
Sbjct: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
Query: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP
Sbjct: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS
Sbjct: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
Query: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP
Sbjct: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
Query: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA 536
PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQ + A
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAAAMA 536
Score = 32.0 bits (71), Expect = 1.8
Identities = 37/143 (25%), Positives = 40/143 (27%), Gaps = 45/143 (31%)
Query: 524 PWQQ-------NTTTTTTSAGTGSIP-------PWQQQQA-----------------AAA 552
PWQ NTT T G G I P Q A A
Sbjct: 264 PWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEA 323
Query: 553 ASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPP--------PPPPGSAGMMIPP----- 599
P + P PL +P P PPPP PP S P
Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
Query: 600 -RGGDGPSHESEDFPRPLVTLPG 621
G GP FP PL +L G
Sbjct: 384 GGGPGGPGGGPHSFPHPLPSLTG 406
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 115 bits (288), Expect = 1e-25
Identities = 112/325 (34%), Positives = 132/325 (40%), Gaps = 52/325 (16%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P+P + S+S P L P P P P+L ST +PP + P +
Sbjct: 860 PLPCTESSSSMPG---LGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP 916
Query: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ---PPPPPMNQG--PHP 438
G G P P + PLP L G G P PPPP PPPPP+ P P
Sbjct: 917 GAGIPPPPPLPGAGILPLPPLPGA--GIP-------PPPPLPGAAIPPPPPLPGAGIPLP 967
Query: 439 PGHHG----PPPMDQYLGSTPV----GSGVYRLHQ--GKGMMPPPPM---GMMPPPPPPP 485
P G PPP G P G+G+ G G+ PPPP+ G+ PPPP P
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027
Query: 486 SGQPPPPPSG----PLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541
+G PPPPP P PP PPPPP P + + PLP G G
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP------------GAGIP 1075
Query: 542 PPWQQQQAAAAASPGAPQMQGNPTMVPLPP-GVQPPLP-PGAPPPPPPPPPGSAGMMIPP 599
PP A P P G P PLP G+ PP P PGA PPPPP PG+ PP
Sbjct: 1076 PPPPLPGAGIPPPPPLPGA-GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134
Query: 600 RGGDGPSHESEDFPRPLVTLPGRQP 624
G G P P V +P P
Sbjct: 1135 LPGAGIPPPP---PLPRVGIPPPPP 1156
Score = 112 bits (279), Expect = 1e-24
Identities = 101/298 (33%), Positives = 116/298 (38%), Gaps = 63/298 (21%)
Query: 324 PVPASVGSTSGPATTPLASA----PRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
P P + + P PL A P P A PPPP L PP + P P
Sbjct: 943 PPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPL---PGAGIP- 998
Query: 380 HGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ----PPPPPMNQG 435
P PG G P P P G P PPPP + PPPPP+
Sbjct: 999 -----PPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1050
Query: 436 PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM---GMMPPPPPPPSGQPPPP 492
PP PPP+ G G+ PPPP+ G+ PPPP P +G PPPP
Sbjct: 1051 GIPP----PPPLP-----------------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089
Query: 493 PSG----PLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQ 548
P P PP PPPPP P + + PLP G G PP
Sbjct: 1090 PLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP------------GAGIPPPPPLPG 1137
Query: 549 AAAAASPGAPQMQGNPTMVPLP-PGVQPPLP-PGAPPPPPPPPPGSAGMMIPPRGGDG 604
A P P++ G P PLP G+ PP P PGA PPPPP PG PP G G
Sbjct: 1138 AGIPPPPPLPRV-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVG 1194
Score = 111 bits (277), Expect = 2e-24
Identities = 103/302 (34%), Positives = 117/302 (38%), Gaps = 49/302 (16%)
Query: 324 PVPASVGSTSGPATTPLASA---PRPAAP-ANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
P P + P PL A P P P A PPPP L PP + P
Sbjct: 910 PPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP- 968
Query: 380 HGMHGGG----PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ----PPPPP 431
+ G G P PG G P P P G P PPPP + PPPPP
Sbjct: 969 -PLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024
Query: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM---GMMPPPPPPPSGQ 488
+ PP PPP+ G G+ PPPP+ G+ PPPP P +G
Sbjct: 1025 LPGAGIPP----PPPLP-----------------GAGIPPPPPLPGAGIPPPPPLPGAGI 1063
Query: 489 PPPPPSG----PLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPW 544
PPPPP P PP PPPPP P + + PLP G G PP
Sbjct: 1064 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV-GIPPPPPLPGAGIPPPP 1122
Query: 545 QQQQAAAAASPGAPQMQGNPTMVPLPP-GVQPPLP-PGAPPPPPPPPPGSAGMMIPPRGG 602
A P P G P PLP G+ PP P PGA PPPPP PG+ PP G
Sbjct: 1123 PLPGAGIPPPPPLPGA-GIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1181
Query: 603 DG 604
G
Sbjct: 1182 VG 1183
Score = 106 bits (264), Expect = 7e-23
Identities = 110/338 (32%), Positives = 129/338 (38%), Gaps = 55/338 (16%)
Query: 324 PVPASVGSTSGPATTPLASA----PRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
P+P + P PL A P P A PPPP L PP + P
Sbjct: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP- 1023
Query: 380 HGMHGGG----PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ----PPPPP 431
+ G G P PG G P P P G P PPPP + PPPPP
Sbjct: 1024 -PLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1079
Query: 432 MNQG--PHPPGHHG----PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM---GMMPPPP 482
+ P PP G PPP +G P G G+ PPPP+ G+ PPPP
Sbjct: 1080 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP-----LPGAGIPPPPPLPGAGIPPPPP 1134
Query: 483 PPPSGQPPPPPSG----PLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGT 538
P +G PPPPP P PP PPPPP P + + PLP G
Sbjct: 1135 LPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV-GIPPPPPLPGV 1193
Query: 539 GSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL-PPGAPPPPPPPPPGSAGMMI 597
G PP A P P + G + +PP PPL PPG PPPP P S ++
Sbjct: 1194 GIPPP---PPLPGAGIPPPPPLPG----MGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLL 1246
Query: 598 PPRGGDGPSHESEDFPRPLVTLPGRQPQQRPWWTGWFG 635
P G S P P V G P P +G FG
Sbjct: 1247 PQVG-------SSTLPTPQVC--GFLPPPLP--SGLFG 1273
Score = 102 bits (254), Expect = 1e-21
Identities = 92/272 (33%), Positives = 106/272 (38%), Gaps = 40/272 (14%)
Query: 353 PPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLP-------SLT 405
PPPPSL+ + P S S + H + P P P S
Sbjct: 811 PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSM 870
Query: 406 GGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG----PPPMDQYLGSTPVGSGVY 461
G G P P PP P M P P P PP G PPP G+ G
Sbjct: 871 PGLGMVP----PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA---GIPPP 923
Query: 462 RLHQGKGMMPPPPM---GMMPPPPPPPSGQPPPPPSG----PLPPWQQQQQQPPPPPPPS 514
G G++P PP+ G+ PPPP P + PPPPP PLPP PPPPP P
Sbjct: 924 PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPG 983
Query: 515 SSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLP-PGV 573
+ + PLP G G PP A P P G P PLP G+
Sbjct: 984 AGIPPPPPLP------------GAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGI 1030
Query: 574 QPPLP-PGAPPPPPPPPPGSAGMMIPPRGGDG 604
PP P PGA PPPPP PG+ PP G G
Sbjct: 1031 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1062
Score = 89.4 bits (220), Expect = 9e-18
Identities = 82/255 (32%), Positives = 102/255 (40%), Gaps = 34/255 (13%)
Query: 378 PYHGMHGGGPGGPGG--GPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPM--- 432
P G+ G P PG GP + SL +Q + + P QPPPPP
Sbjct: 759 PVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLW 818
Query: 433 NQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM------------GMMPP 480
+ G PG P + ++ S + PPP+ GM+PP
Sbjct: 819 SAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPP 878
Query: 481 PPPPPSGQPPPP-PSGPLP---PWQQQQQQPPPPPP-PSSSMASSTPLPWQQNTTTTTTS 535
PPPP G P PS +P P Q + PPPPPP P + + PLP
Sbjct: 879 PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGA-GILPLPPL 937
Query: 536 AGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP-----GVQPPLP-PGAPPPPPPPP 589
G G PP AA P P + G +PLPP G+ PP P PGA PPPPP
Sbjct: 938 PGAGIPPP---PPLPGAAIPPPPPLPG--AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPL 992
Query: 590 PGSAGMMIPPRGGDG 604
PG+ PP G G
Sbjct: 993 PGAGIPPPPPLPGAG 1007
Score = 30.4 bits (67), Expect = 5.2
Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 11/80 (13%)
Query: 559 QMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHES--------- 609
Q+Q L +P PP A P P G ++ P GG G + S
Sbjct: 216 QLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSA 275
Query: 610 -EDFPRPLVTLPGRQPQQRP 628
D P L P R+PQQ P
Sbjct: 276 LSDLPESLAAEP-REPQQPP 294
>gi|42544127 splicing factor 1 isoform 4 [Homo sapiens]
Length = 80
Score = 112 bits (281), Expect = 8e-25
Identities = 56/68 (82%), Positives = 59/68 (86%), Gaps = 6/68 (8%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYI------V 54
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYI +
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIGKYTFCI 60
Query: 55 QLQIEDLT 62
Q+ E +T
Sbjct: 61 QMHFEIVT 68
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 112 bits (281), Expect = 8e-25
Identities = 107/337 (31%), Positives = 125/337 (37%), Gaps = 68/337 (20%)
Query: 311 KEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPP-PPSLMSTTQSRPPWM 369
+E SL+A + P GP + P P N P PP Q PP
Sbjct: 26 EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 85
Query: 370 NSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP-----PW 424
+ P P PG P G P P P GPPP P
Sbjct: 86 GNKPQGPPP--------PGKPQGPP-------PQGDKSRSPRSPPGKPQGPPPQGGNQPQ 130
Query: 425 MQPPPPPMNQGPHPPGHH---GPPPMDQYLGSTPVGSGVYRLHQ---GKGMMPPPPMGMM 478
PPPP QGP P G + GPPP + G P G R + GK PPP G
Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQ 190
Query: 479 PPPPPPPSGQP--PPP-----PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTT 531
P PPPP G+P PPP P GP PP + Q PPP + S ++ +P Q
Sbjct: 191 PQGPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQGPPPQGDNKSQSARSPPGKPQGPPP 247
Query: 532 TTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQ--PP-----------LP 578
+ G PP + Q G P GN P PPG PP P
Sbjct: 248 QGGNQPQGPPPPPGKPQ-------GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300
Query: 579 PGAP--PPP--------PPPPPGSAGMMIPPRGGDGP 605
PG P PPP PPPPPG PP+GG+ P
Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKP-QGPPPQGGNKP 336
Score = 111 bits (277), Expect = 2e-24
Identities = 107/332 (32%), Positives = 118/332 (35%), Gaps = 82/332 (24%)
Query: 344 PRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPL-- 401
P P PPP S + PP GP P G GP P G P P P
Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQG-PPPQGG 147
Query: 402 -----PSLTGGHGGHPMQHN------------PNGPPP-----PWMQPPPPPMNQGPHPP 439
P G G P Q + P GPPP P PPPP QGP P
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 207
Query: 440 GHH---GPPPMDQYLGSTPVG---SGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQP--PP 491
G + GPPP + G P G S R GK PPP G P PPPP G+P PP
Sbjct: 208 GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 267
Query: 492 P-----PSGPLPPWQQQ--------------------QQQPP--------PPPPPSSSMA 518
P P GP PP + Q Q PP PPPPP
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 327
Query: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQ-QQAAAAASP-----GAPQMQGNPTMVPLPPG 572
P P N G PP Q ++ +A SP G PQ +GN P PP
Sbjct: 328 ---PPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPA 384
Query: 573 ----VQPPLPPGAPPPPPPPPPGSAGMMIPPR 600
QP PP P PP PP PP+
Sbjct: 385 GGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416
Score = 107 bits (268), Expect = 3e-23
Identities = 104/328 (31%), Positives = 122/328 (37%), Gaps = 49/328 (14%)
Query: 340 LASAPRPAAP--ANNPP-PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHS 396
+A P+ A P N P PPS Q PP + P P G G P G P
Sbjct: 32 IAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 91
Query: 397 FPHPL----PSLTGGHGGHPMQH--NPNGPPP-----PWMQPPPPPMNQGPHPPGHH--- 442
P P P G P P GPPP P PPPP QGP P G +
Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 151
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQ---GKGMMPPPPMGMMPPPPPPPSGQP--PPP----- 492
GPPP + G P G R + GK PPP G P PPPP G+P PPP
Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 211
Query: 493 PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAA 552
P GP PP + Q PPP + S ++ +P Q + G PP + Q
Sbjct: 212 PQGPPPPGKPQG---PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ---- 264
Query: 553 ASPGAPQMQGNPTMVPLPPGV-QPPLPPGAP-----------PPPPPPPPGSAGMMIPPR 600
G P GN P PPG Q P P G P PPP G+ PP
Sbjct: 265 ---GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPP 321
Query: 601 GGDGPSHESEDFPRPLVTLPGRQPQQRP 628
G + +P P +PQ P
Sbjct: 322 PGKPQGPPPQGGNKPQGPPPPGKPQGPP 349
Score = 103 bits (258), Expect = 4e-22
Identities = 95/302 (31%), Positives = 105/302 (34%), Gaps = 61/302 (20%)
Query: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
+ P P GP P P P PP S + PP GP P G
Sbjct: 140 QGPPPQGGNKPQGP--------PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP---PQGG 188
Query: 382 MHGGGPGGPGGGPHSFPHPL-------PSLTGGHGGHPMQHN------------PNGPPP 422
GP P G P P P P G G P Q + P GPPP
Sbjct: 189 NQPQGPPPPPGKPQG-PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247
Query: 423 -----PWMQPPPPPMNQGPHPPGHH---GPPPMDQYLGSTPVGSGVYRLHQ---GKGMMP 471
P PPPP QGP P G + GPPP + G P G R + GK P
Sbjct: 248 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307
Query: 472 PPPMGMMPPPPPPPSGQP--PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNT 529
PP G P PPPP G+P PPP G P +P PPP S + S P
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP----- 362
Query: 530 TTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQP---PLPPGAPPPPP 586
G PP Q+ P A GNP PP QP P PP P
Sbjct: 363 ------PGKPQGPPQQEGNNPQGPPPPAG---GNPQQPQAPPAGQPQGPPRPPQGGRPSR 413
Query: 587 PP 588
PP
Sbjct: 414 PP 415
Score = 90.9 bits (224), Expect = 3e-18
Identities = 79/251 (31%), Positives = 90/251 (35%), Gaps = 46/251 (18%)
Query: 402 PSLTGGHG-GHPMQ--HNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGS 458
PSL G+ G P Q + P GPP P +P PP G P G PP
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPP------------- 75
Query: 459 GVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSG------------PLPPWQQQQQQ 506
GK PPP G P PPPP PPP G P P Q Q
Sbjct: 76 -------GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 128
Query: 507 PPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQ----MQG 562
P PPPP P + G P + ++ + PG PQ G
Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188
Query: 563 NPTMVPLPPGVQP--PLPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFP-RPLVTL 619
N P PP +P P P G P PPPPG PP GD S + P +P
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--QGPPPQGDNKSQSARSPPGKPQGPP 246
Query: 620 P--GRQPQQRP 628
P G QPQ P
Sbjct: 247 PQGGNQPQGPP 257
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 112 bits (279), Expect = 1e-24
Identities = 105/325 (32%), Positives = 118/325 (36%), Gaps = 54/325 (16%)
Query: 311 KEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMN 370
+E SL+A + P P GP P P N P P Q PP +
Sbjct: 26 EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 85
Query: 371 SGPSESRPYHGMHGGGPGGP---GGGPHSFPHPLPSLTGGHGGHPMQ--HNPNGPPPPWM 425
S P G P GP GG P P P G G P Q + P GPPPP
Sbjct: 86 KSRSPRSP-----PGKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQGGNRPQGPPPPGK 137
Query: 426 QPPPPPM---NQGPH-PPGH-HGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPP ++ P PPG GPPP G+ P G GK PPP G P
Sbjct: 138 PQGPPPQGDKSRSPRSPPGKPQGPPPQG---GNQPQGPPP---PPGKPQGPPPQGGKKPQ 191
Query: 481 PPPPP---------------SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPW 525
PPPP S PP P GP P Q Q PPPPP P P
Sbjct: 192 GPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQG-----PPPQ 246
Query: 526 QQNTTTTTTSAGTGSIPPWQ-QQQAAAAASP-----GAPQMQGNPTMVPLPPG----VQP 575
N G PP Q ++ +A SP G PQ +GN P PP QP
Sbjct: 247 GGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 306
Query: 576 PLPPGAPPPPPPPPPGSAGMMIPPR 600
PP P PP PP PP+
Sbjct: 307 QAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 92.0 bits (227), Expect = 1e-18
Identities = 80/243 (32%), Positives = 92/243 (37%), Gaps = 36/243 (14%)
Query: 410 GHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHH---GPPPMDQYLGSTPVG--SGVYRLH 464
G+P +P G P PPPP QGP P G + GPPP + G P G S R
Sbjct: 34 GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
Query: 465 QGKGMMPPPPMGMMPPPPPPPSGQP--PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
GK PPP G P PPPP G+P PPP G P Q PPPP P P
Sbjct: 94 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP------QGPPPPGKPQG------P 141
Query: 523 LPWQQNTTTTTTSAGTGSIPPWQ--QQQAAAAASPGAPQ----MQGNPTMVPLPPGV-QP 575
P + + + G PP Q Q PG PQ G P PPG Q
Sbjct: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG 201
Query: 576 PLPPG----------APPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQPQ 625
P P G P PPP G+ PP G + +P P +PQ
Sbjct: 202 PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 261
Query: 626 QRP 628
P
Sbjct: 262 GPP 264
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 107 bits (268), Expect = 3e-23
Identities = 121/497 (24%), Positives = 175/497 (35%), Gaps = 79/497 (15%)
Query: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221
R +GS+ + GRK DG+ P G + P A ++N E VKK+ ++
Sbjct: 22 RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 81
Query: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281
++ +++ + Q + E R + + I RP SE ++ +
Sbjct: 82 VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 140
Query: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334
G+ I D + P P +++ D ++ L +AP + +S
Sbjct: 141 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 200
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388
P TP P P A PP S T S+ P P+ P+ +H P
Sbjct: 201 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 258
Query: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442
P PH PHP G G P + PP PP P P+ Q P PP
Sbjct: 259 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 318
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGM-------------------MPPPPMGM---MPP 480
G PP G P+G+ + + +PP P+ M PP
Sbjct: 319 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 377
Query: 481 P-------PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTP----LPWQQNT 529
P P P + + PP SGP P PPP P SS+++ P P Q
Sbjct: 378 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 437
Query: 530 TTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPP- 588
+ + + PP Q P + G + P PP Q P PG PPP PP
Sbjct: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT 497
Query: 589 ------PPGSAGMMIPP 599
PP G P
Sbjct: 498 CPSTSTPPAGPGTSAQP 514
Score = 50.8 bits (120), Expect = 4e-06
Identities = 54/184 (29%), Positives = 64/184 (34%), Gaps = 38/184 (20%)
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
P P D S S ++ Q + P G+ P P P G P P GP P
Sbjct: 162 PSPQDNESDSD--SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTP----S 215
Query: 504 QQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563
PP P++S A + P A T +P QQA A PQ
Sbjct: 216 ATAVPPQGSPTASQAPNQP------------QAPTAPVPHTHIQQAPALH----PQR--- 256
Query: 564 PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGM------MIPPRGGDGPSHESEDFPRPLV 617
PP PP P +P PP P GSAG PP G GP PL+
Sbjct: 257 ------PPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 309
Query: 618 TLPG 621
PG
Sbjct: 310 QHPG 313
Score = 45.4 bits (106), Expect = 2e-04
Identities = 34/113 (30%), Positives = 46/113 (40%), Gaps = 9/113 (7%)
Query: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPP-- 576
SS P Q+ +T+ S IP Q ++ + +S +Q P + P GV P
Sbjct: 144 SSDPKDIDQDNRSTSPS-----IPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS 198
Query: 577 -LPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQPQQRP 628
PPG P P P P SA +PP+G S P +P QQ P
Sbjct: 199 SAPPGTPQLPTPGPTPSA-TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 250
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 107 bits (268), Expect = 3e-23
Identities = 121/497 (24%), Positives = 175/497 (35%), Gaps = 79/497 (15%)
Query: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221
R +GS+ + GRK DG+ P G + P A ++N E VKK+ ++
Sbjct: 576 RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 635
Query: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281
++ +++ + Q + E R + + I RP SE ++ +
Sbjct: 636 VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 694
Query: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334
G+ I D + P P +++ D ++ L +AP + +S
Sbjct: 695 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 754
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388
P TP P P A PP S T S+ P P+ P+ +H P
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 812
Query: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442
P PH PHP G G P + PP PP P P+ Q P PP
Sbjct: 813 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 872
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGM-------------------MPPPPMGM---MPP 480
G PP G P+G+ + + +PP P+ M PP
Sbjct: 873 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 931
Query: 481 P-------PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTP----LPWQQNT 529
P P P + + PP SGP P PPP P SS+++ P P Q
Sbjct: 932 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991
Query: 530 TTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPP- 588
+ + + PP Q P + G + P PP Q P PG PPP PP
Sbjct: 992 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT 1051
Query: 589 ------PPGSAGMMIPP 599
PP G P
Sbjct: 1052 CPSTSTPPAGPGTSAQP 1068
Score = 50.8 bits (120), Expect = 4e-06
Identities = 54/184 (29%), Positives = 64/184 (34%), Gaps = 38/184 (20%)
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
P P D S S ++ Q + P G+ P P P G P P GP P
Sbjct: 716 PSPQDNESDSD--SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTP----S 769
Query: 504 QQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563
PP P++S A + P A T +P QQA A PQ
Sbjct: 770 ATAVPPQGSPTASQAPNQP------------QAPTAPVPHTHIQQAPALH----PQR--- 810
Query: 564 PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGM------MIPPRGGDGPSHESEDFPRPLV 617
PP PP P +P PP P GSAG PP G GP PL+
Sbjct: 811 ------PPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 863
Query: 618 TLPG 621
PG
Sbjct: 864 QHPG 867
Score = 45.4 bits (106), Expect = 2e-04
Identities = 34/113 (30%), Positives = 46/113 (40%), Gaps = 9/113 (7%)
Query: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPP-- 576
SS P Q+ +T+ S IP Q ++ + +S +Q P + P GV P
Sbjct: 698 SSDPKDIDQDNRSTSPS-----IPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS 752
Query: 577 -LPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQPQQRP 628
PPG P P P P SA +PP+G S P +P QQ P
Sbjct: 753 SAPPGTPQLPTPGPTPSA-TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 804
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 107 bits (268), Expect = 3e-23
Identities = 121/497 (24%), Positives = 175/497 (35%), Gaps = 79/497 (15%)
Query: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221
R +GS+ + GRK DG+ P G + P A ++N E VKK+ ++
Sbjct: 576 RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 635
Query: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281
++ +++ + Q + E R + + I RP SE ++ +
Sbjct: 636 VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 694
Query: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334
G+ I D + P P +++ D ++ L +AP + +S
Sbjct: 695 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 754
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388
P TP P P A PP S T S+ P P+ P+ +H P
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 812
Query: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442
P PH PHP G G P + PP PP P P+ Q P PP
Sbjct: 813 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 872
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGM-------------------MPPPPMGM---MPP 480
G PP G P+G+ + + +PP P+ M PP
Sbjct: 873 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 931
Query: 481 P-------PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTP----LPWQQNT 529
P P P + + PP SGP P PPP P SS+++ P P Q
Sbjct: 932 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991
Query: 530 TTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPP- 588
+ + + PP Q P + G + P PP Q P PG PPP PP
Sbjct: 992 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT 1051
Query: 589 ------PPGSAGMMIPP 599
PP G P
Sbjct: 1052 CPSTSTPPAGPGTSAQP 1068
Score = 50.8 bits (120), Expect = 4e-06
Identities = 54/184 (29%), Positives = 64/184 (34%), Gaps = 38/184 (20%)
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
P P D S S ++ Q + P G+ P P P G P P GP P
Sbjct: 716 PSPQDNESDSD--SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTP----S 769
Query: 504 QQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563
PP P++S A + P A T +P QQA A PQ
Sbjct: 770 ATAVPPQGSPTASQAPNQP------------QAPTAPVPHTHIQQAPALH----PQR--- 810
Query: 564 PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGM------MIPPRGGDGPSHESEDFPRPLV 617
PP PP P +P PP P GSAG PP G GP PL+
Sbjct: 811 ------PPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 863
Query: 618 TLPG 621
PG
Sbjct: 864 QHPG 867
Score = 45.4 bits (106), Expect = 2e-04
Identities = 34/113 (30%), Positives = 46/113 (40%), Gaps = 9/113 (7%)
Query: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPP-- 576
SS P Q+ +T+ S IP Q ++ + +S +Q P + P GV P
Sbjct: 698 SSDPKDIDQDNRSTSPS-----IPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS 752
Query: 577 -LPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQPQQRP 628
PPG P P P P SA +PP+G S P +P QQ P
Sbjct: 753 SAPPGTPQLPTPGPTPSA-TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP 804
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 105 bits (263), Expect = 1e-22
Identities = 106/352 (30%), Positives = 127/352 (36%), Gaps = 80/352 (22%)
Query: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS--ESRP 378
G PVP S G SGP P P PP P + S S PP + S P +S P
Sbjct: 148 GRFPVP-SPGHRSGP--------PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
Query: 379 YHGMHGGGPGGP-----GGGPHSFPHPLPSLTGG--------HGGHPMQHNPNGPPPPWM 425
++ PGGP G P FP + GG P + P PP P
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258
Query: 426 ----QPPPPPMNQGPHPPGHHG--PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP 479
+PPPPP G P H PPP Q PV S + PPPP
Sbjct: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQN-NKPPVPSTPRPSASSQAPPPPPPPSRPG 317
Query: 480 PPPPPPSGQ----------------------PPPPPSGPLPPWQQQQQQPPPPPPPSSSM 517
PPP PPS P P SGPLPP ++ PPPP
Sbjct: 318 PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER----PPPPVRDPP 373
Query: 518 ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL 577
S PLP PP + + + A P PQ+ + G +PPL
Sbjct: 374 GRSGPLP---------------PPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL 418
Query: 578 PP-----GAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQP 624
PP GAPPPPPP G P + ES + P+ LP +P
Sbjct: 419 PPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE---WESRFYFHPISDLPPPEP 467
Score = 102 bits (254), Expect = 1e-21
Identities = 98/326 (30%), Positives = 120/326 (36%), Gaps = 45/326 (13%)
Query: 327 ASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG 386
A+ + SG + PL + A PPS P SGP E P
Sbjct: 115 ANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPE--PQRNRMPPP 172
Query: 387 PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPP 446
G P S P P+PS P HN PP P P P P PG+ G
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSP--HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTAL 230
Query: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM---PPPPPPPSGQ---------PPPPPS 494
+ +P+ S + +PP P + PPPPPPP G PPPPP
Sbjct: 231 GGGSIRQSPLSSS--SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 495 GPLPPW------QQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQ 548
PP Q PPPPPPP S PLP +S+G P Q+
Sbjct: 289 NNKPPVPSTPRPSASSQAPPPPPPP--SRPGPPPLP--------PSSSGNDETPRLPQRN 338
Query: 549 AAAAASPGAPQMQGNPTMVPLPPGVQPPL----PPGAPPPPPPPPP----GSAGMMIPPR 600
+ ++S G +P PP +PP PPG P PPPPP GS +P
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT 398
Query: 601 GGDGPSHESEDFPR--PLVTLPGRQP 624
PS D PR P LP +P
Sbjct: 399 -PQLPSRSGVDSPRSGPRPPLPPDRP 423
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 105 bits (263), Expect = 1e-22
Identities = 106/352 (30%), Positives = 127/352 (36%), Gaps = 80/352 (22%)
Query: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS--ESRP 378
G PVP S G SGP P P PP P + S S PP + S P +S P
Sbjct: 148 GRFPVP-SPGHRSGP--------PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
Query: 379 YHGMHGGGPGGP-----GGGPHSFPHPLPSLTGG--------HGGHPMQHNPNGPPPPWM 425
++ PGGP G P FP + GG P + P PP P
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258
Query: 426 ----QPPPPPMNQGPHPPGHHG--PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP 479
+PPPPP G P H PPP Q PV S + PPPP
Sbjct: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQN-NKPPVPSTPRPSASSQAPPPPPPPSRPG 317
Query: 480 PPPPPPSGQ----------------------PPPPPSGPLPPWQQQQQQPPPPPPPSSSM 517
PPP PPS P P SGPLPP ++ PPPP
Sbjct: 318 PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER----PPPPVRDPP 373
Query: 518 ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL 577
S PLP PP + + + A P PQ+ + G +PPL
Sbjct: 374 GRSGPLP---------------PPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL 418
Query: 578 PP-----GAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQP 624
PP GAPPPPPP G P + ES + P+ LP +P
Sbjct: 419 PPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE---WESRFYFHPISDLPPPEP 467
Score = 102 bits (254), Expect = 1e-21
Identities = 98/326 (30%), Positives = 120/326 (36%), Gaps = 45/326 (13%)
Query: 327 ASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG 386
A+ + SG + PL + A PPS P SGP E P
Sbjct: 115 ANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPE--PQRNRMPPP 172
Query: 387 PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPP 446
G P S P P+PS P HN PP P P P P PG+ G
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSP--HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTAL 230
Query: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM---PPPPPPPSGQ---------PPPPPS 494
+ +P+ S + +PP P + PPPPPPP G PPPPP
Sbjct: 231 GGGSIRQSPLSSS--SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 495 GPLPPW------QQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQ 548
PP Q PPPPPPP S PLP +S+G P Q+
Sbjct: 289 NNKPPVPSTPRPSASSQAPPPPPPP--SRPGPPPLP--------PSSSGNDETPRLPQRN 338
Query: 549 AAAAASPGAPQMQGNPTMVPLPPGVQPPL----PPGAPPPPPPPPP----GSAGMMIPPR 600
+ ++S G +P PP +PP PPG P PPPPP GS +P
Sbjct: 339 LSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT 398
Query: 601 GGDGPSHESEDFPR--PLVTLPGRQP 624
PS D PR P LP +P
Sbjct: 399 -PQLPSRSGVDSPRSGPRPPLPPDRP 423
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 103 bits (258), Expect = 4e-22
Identities = 85/257 (33%), Positives = 95/257 (36%), Gaps = 71/257 (27%)
Query: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440
G H G GG GG H F P P + G P GP P P PP PP
Sbjct: 15 GFHRRGGGGGRGGLHDFRSPPPGM-----GLNQNRGPMGPGPGQSGPKPPI------PP- 62
Query: 441 HHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPW 500
PPP Q PPP PPP PP QPPP P
Sbjct: 63 ---PPPHQQQ------------------QQPPP---QQPPPQQPPPHQPPPHP------- 91
Query: 501 QQQQQQPPPPPPPSSS--MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAP 558
Q QQQ PPPPP SS + + P P + G GS PP A+++A P P
Sbjct: 92 QPHQQQQPPPPPQDSSKPVVAQGPGP----------APGVGSAPP-----ASSSAPPATP 136
Query: 559 QMQG-----NPTMVPLPPGVQPPLPPGAPPPPPP------PPPGSAGMMIPPRGGDGPSH 607
G P P PP PPGAPPP PP PP + G PP GP
Sbjct: 137 PTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP 196
Query: 608 ESEDFPRPLVTLPGRQP 624
+ P P G+ P
Sbjct: 197 GPKQGPGPGGPKGGKMP 213
Score = 75.1 bits (183), Expect = 2e-13
Identities = 78/276 (28%), Positives = 85/276 (30%), Gaps = 79/276 (28%)
Query: 339 PLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFP 398
P+ P + P PPP Q PP P + P P
Sbjct: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPP--QQPPPQQPP-------------------P 84
Query: 399 HPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGS 458
H P HP H PPPP P + QGP GP P VGS
Sbjct: 85 HQPPP-------HPQPHQQQQPPPPPQDSSKPVVAQGP------GPAP--------GVGS 123
Query: 459 GVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMA 518
PP PP PP SG PP GP P PPP S+
Sbjct: 124 A------------PPASSSAPPATPPTSGAPPGSGPGPTP--------TPPPAVTSAPPG 163
Query: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLP 578
+ P P TT AG PP AA PG QG PG P P
Sbjct: 164 APPPTPPSSGVPTTPPQAGGPPPPP------AAVPGPGPGPKQG--------PG--PGGP 207
Query: 579 PGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPR 614
G P P P G G+ P G P H PR
Sbjct: 208 KGGKMPGGPKPGGGPGLS-TPGGHPKPPHRGGGEPR 242
Score = 67.8 bits (164), Expect = 3e-11
Identities = 58/187 (31%), Positives = 68/187 (36%), Gaps = 30/187 (16%)
Query: 344 PRPAAPANNPPPPSLMST------------TQSRPPWMNSGPSESRPYHGMHGGGPGGPG 391
P+P PPPP S S PP +S P + P G PG
Sbjct: 91 PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG------APPG 144
Query: 392 GGPHSFPHPLPSLTGGHGGHPMQHNPNG-----PPPPWMQPPPPPMNQGPHPPGHHGPPP 446
GP P P P++T G P P+ PP PPPP GP P GP P
Sbjct: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP 204
Query: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQ 506
G P G + G G+ P G P PP G+P PP+ QQ Q
Sbjct: 205 GGPKGGKMPGGP---KPGGGPGLSTP---GGHPKPPHRGGGEPRGGRQHH-PPYHQQHHQ 257
Query: 507 PPPPPPP 513
PPP P
Sbjct: 258 GPPPGGP 264
Score = 62.4 bits (150), Expect = 1e-09
Identities = 55/174 (31%), Positives = 62/174 (35%), Gaps = 31/174 (17%)
Query: 457 GSGVYRLHQGKGMMPPPPMGMMPPPPP--PPSGQPPPPPSGPLPPWQQQQQQPPPPPPPS 514
G G LH + PPP MG+ P P GQ P P P PP QQQQQPPP PP
Sbjct: 22 GGGRGGLHDFRS--PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPP 79
Query: 515 SSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQ 574
P P Q P QQQQ P P + +V PG
Sbjct: 80 QQPPPHQPPPHPQ---------------PHQQQQ------PPPPPQDSSKPVVAQGPGPA 118
Query: 575 PPLPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQPQQRP 628
P + APP PP + PP G P P P + P P
Sbjct: 119 PGVG-SAPPASSSAPPAT-----PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP 166
Score = 61.6 bits (148), Expect = 2e-09
Identities = 56/158 (35%), Positives = 66/158 (41%), Gaps = 31/158 (19%)
Query: 320 LGEAPVPASVGSTSGPATTPLASAPRPAAPANNP-PPPSLMSTTQSRPPWMNSGPSESRP 378
+G AP PAS S++ PAT P + AP + P P PPP++ S PP + PS P
Sbjct: 121 VGSAP-PAS--SSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP--PTPPSSGVP 175
Query: 379 YHGMHGGGPG-------GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP---PWMQP- 427
GGP GPG GP P P GG G M P GP P P +
Sbjct: 176 TTPPQAGGPPPPPAAVPGPGPGPKQGPGP-----GGPKGGKM---PGGPKPGGGPGLSTP 227
Query: 428 ---PPPPMNQGPHPPG---HHGPPPMDQYLGSTPVGSG 459
P PP G P G HH P + G P G G
Sbjct: 228 GGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPG 265
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 102 bits (253), Expect = 1e-21
Identities = 92/332 (27%), Positives = 117/332 (35%), Gaps = 37/332 (11%)
Query: 326 PASVGSTSGPATTPLASAPR--PAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P +T P P + +P+ P PA PP P T S P W + P+ + P
Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS-PKWAPTPPAATPP---SP 973
Query: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPP-PPWMQPPPP-------PMNQG 435
GGP P P P P + G P +P G P PP + PP P P +G
Sbjct: 974 KGGPATPS--PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031
Query: 436 PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPP----PPPPSGQPPP 491
P PP +TP+ G +P P G P P PP+ PP
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAAT--LPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 492 PPSGPLPPWQQQQQQPPPPPPPSSSMASSTP----LPWQQNTTTTTTSAGTGSIPPWQQQ 547
P GP P + PP PPS +TP P T + G + PP
Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149
Query: 548 QAAAAASP------GAPQMQGNPTMVPLPP-----GVQPPLPPGAPPPPPPPPPGSAGMM 596
AA P P +G PT P G+ P P GAP P PP G +
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1209
Query: 597 IPPRGGDGPSHESEDFPRPLVTLPGRQPQQRP 628
P P+ + P P L P+ P
Sbjct: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241
Score = 91.7 bits (226), Expect = 2e-18
Identities = 92/327 (28%), Positives = 113/327 (34%), Gaps = 41/327 (12%)
Query: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385
PA+ G TTP A+ P P P + + PP GP+ P G
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK-----G 1101
Query: 386 GPGGPGGGPHSFPHPLPSL-TGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGP 444
P P P P P L T H G P P P PPP P P P
Sbjct: 1102 APMPPAATP---PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKG-APTTPAATPP 1157
Query: 445 PPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP-----PSGQPPPPPSGPLPP 499
P P G+ PP P G + P P P+ PP P G P
Sbjct: 1158 SPKGGLATPPPKGAPTT-----PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212
Query: 500 WQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA---GTGSIPPWQQQQAAAAASPG 556
+ P PPS +TP P TT T G + PP + AA+P
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP- 1271
Query: 557 APQMQG-----------NPTMV--PLPPGVQPPLPP-GAPPPP--PPPPPGSAGMMIPPR 600
P ++G NP +V P P G PP GAP PP PP P + PP+
Sbjct: 1272 -PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330
Query: 601 GGDGPSHESEDFPRPLVTLPGRQPQQR 627
G P + P+ TLP P +
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Score = 88.2 bits (217), Expect = 2e-17
Identities = 100/380 (26%), Positives = 125/380 (32%), Gaps = 71/380 (18%)
Query: 298 GDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATT-------PLASAPR--PAA 348
G P S K + + G P+ + + PA T P +P+ P
Sbjct: 929 GIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP 988
Query: 349 PANNPPPPSLMSTTQS----------RPPWMNSGPSESRPYHGMH---GGGPGGPGGGPH 395
PA PP P T S PP P+ + G P P G P
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 396 SFPHP----------LPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPP 445
+ P P LPS GG P + G P P PP P GP P G P
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGG----PATPSLKGAPTPPAATPPSPKG-GPATPSPKGAP 1103
Query: 446 PMDQYLGSTPVGSGVYRLHQG----KGMMPPPPMGMMPPPPP-----PPSGQPPPPPSGP 496
+P G H+G PP P G + PPP P+ PP P G
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 497 LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTT---TTTTSAGTGSIPPWQQQQAAAAA 553
P + P PPS +TP P TT T + G + P + AA
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 554 SPGAPQ---MQGNPTMVPLPPGVQPPLPPGAPPPPPP----------PPPGSAGMMIPPR 600
+P +P+ +P P P PP P G P PPP PP G+ PP
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283
Query: 601 GGDGPSHESEDFPRPLVTLP 620
G P P V P
Sbjct: 1284 KG---------APNPAVVTP 1294
Score = 80.5 bits (197), Expect = 4e-15
Identities = 86/309 (27%), Positives = 108/309 (34%), Gaps = 40/309 (12%)
Query: 334 GPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSG---PSE--------SRPYHGM 382
G TTP A+ P P PPP +T + PP G PS + P
Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206
Query: 383 HGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP----PPPWMQPPPPPMNQGPHP 438
G P G P + PS GG + P P P P P PP P P
Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTP 1266
Query: 439 PGHHGPPPMDQYLGSTPVGSGVYRLHQGKG----MMPPPPMGMMPPPPPPPSGQPPPPPS 494
P PP + L + P H+G + PP P G P PP G P PP +
Sbjct: 1267 PAAT-PPSLKGGLATPP--------HKGAPNPAVVTPPSPKG--GPATSPPKGAPTPPAA 1315
Query: 495 GPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAAS 554
P P PP P ++ +P TT +S G + P ++ AA+
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375
Query: 555 PGAPQMQGNPTMVPLPP--GVQPPLPPGAPPPP---PPPPPGSAGMMIPPRGGDGPSHES 609
P +G P M P P G P P G P P P P + + G PS
Sbjct: 1376 ---PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS--K 1430
Query: 610 EDFPRPLVT 618
D P VT
Sbjct: 1431 GDLTPPAVT 1439
Score = 76.3 bits (186), Expect = 8e-14
Identities = 103/395 (26%), Positives = 124/395 (31%), Gaps = 96/395 (24%)
Query: 317 MAELGEAP-VPASVGSTS-GPATTP------------LASAPRPAAPANNPPPPSLMSTT 362
+A L AP +P SV S S PA TP A AP ++P P S S T
Sbjct: 721 LATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASAT 780
Query: 363 QSR------------PPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLP-------- 402
S P ++ P RP GP P G S P+
Sbjct: 781 ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840
Query: 403 -SLTGGHGGHPMQHNPNGPPP--------------------PWMQPPPPPMN-----QGP 436
S G H+P P P P P P +N +GP
Sbjct: 841 LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
Query: 437 HPPGHHGPPPMDQYLGS------TPVGSGVYRLHQGKGMMPPPPMGMMPPP--------- 481
P P + S TP G+ KG P PP P P
Sbjct: 901 ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA-PTPPAATPPSPKGGPATPSP 959
Query: 482 ---PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGT 538
P PP+ PP P GP P + PP PPS +TP P T T
Sbjct: 960 KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 539 GSIPPWQQQQAAAAASPGA--PQMQGNPTMVPLP------PGVQPPLPPGAPPPP----P 586
P A+ P A P +G+P PLP P P P G P P
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 587 PPPPGSAGMMIPPRGGDGPSHES-EDFPRPLVTLP 620
P PP + PP GP+ S + P P P
Sbjct: 1080 PTPPAAT----PPSPKGGPATPSPKGAPMPPAATP 1110
Score = 62.4 bits (150), Expect = 1e-09
Identities = 87/353 (24%), Positives = 113/353 (32%), Gaps = 77/353 (21%)
Query: 323 APVPASVGSTS---GPATTPLASAPRPAA-----PANNP--PPPSLMSTTQSRPPWMNSG 372
AP PA V S GPAT+P AP P A P +P PPP T + P G
Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345
Query: 373 PSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQH-----------NPNGPP 421
GGP P P P+ T H G P +P G P
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTP---PAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Query: 422 P--------PWMQPPPPPMNQGPHPP--GHHGPPPMDQY------LGSTPVGSGVYRLHQ 465
P P P +G P G PP + S P G +
Sbjct: 1403 TSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK 1462
Query: 466 GKGMMPP--PPMGMMPPPP---------------PPPSGQPPPP---PSGPLPPWQQQQQ 505
G +P PP PP P P P G P P PS P
Sbjct: 1463 GDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSS 1522
Query: 506 QPPPPPPPSSSMASSTP---------------LPWQQNTTTTTTSAGTGSIPPWQQQQAA 550
+ P P ++ ++ TP +P + T T + P ++ +
Sbjct: 1523 RRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582
Query: 551 AAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP--PPPPPGSAGMMIPPRG 601
A +P + +P + +PP V P P AP PP PP P P+G
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635
Score = 61.2 bits (147), Expect = 3e-09
Identities = 69/291 (23%), Positives = 99/291 (34%), Gaps = 42/291 (14%)
Query: 325 VPASVGSTSGPATTPLASAPRPAAPANNP----PPPSLMSTTQSRPPWMNSGPSESRPYH 380
+P+ G + PA PL+ PA P P ++ P + P+ S P
Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK- 1453
Query: 381 GMHGGGPGGPG--GGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHP 438
GGP P G P LP++T +P PP P + P
Sbjct: 1454 ----GGPATPSSKGDP-----TLPAVT--------PPSPKEPPAPKQVATSSSPKKAPAT 1496
Query: 439 PGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498
P G P + + S+P + + P + P + PP+ +P
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556
Query: 499 PWQQQQQQPPP---PPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASP 555
++ P P P PSS ASS P T S G+ P + A SP
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPP--------AVTPSTYKGAPSPKELLIPPAVTSP 1608
Query: 556 GAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDGPS 606
+P P PP V PP P P P P ++ + P D P+
Sbjct: 1609 -------SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652
Score = 51.6 bits (122), Expect = 2e-06
Identities = 67/285 (23%), Positives = 90/285 (31%), Gaps = 14/285 (4%)
Query: 326 PASVGSTSGPATT-----PLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380
PA+ GPAT P A P +P P P + +++ + P +
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506
Query: 381 GMHGGGPGGPGGGPHSFPHPL-PSLTGGHGGHPMQHNPNGPP-PPWMQPPPPPMNQGPHP 438
+ P P S P+ P+ T P P PP M P P
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566
Query: 439 PGHHGPPPMDQYLGSTP-VGSGVYRLHQGKGMMPPPPMGMMPPP---PPPPSGQPPPPPS 494
P P + S P V Y+ + PP P P P PP+ PP P
Sbjct: 1567 PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626
Query: 495 GPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAAS 554
GP P + PP P S + ++P T A G P ++ A
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL--PAKKGPTALKEV 1684
Query: 555 PGAPQMQGNPTM-VPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIP 598
AP + P + P G Q PP P P G P
Sbjct: 1685 LVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGP 1729
Score = 45.8 bits (107), Expect = 1e-04
Identities = 66/275 (24%), Positives = 89/275 (32%), Gaps = 30/275 (10%)
Query: 322 EAPV-PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380
EAP P+S ++S PA TP P+ P PP++ S + P P P
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPS-PKELLIPPAVTSPSPKEAPT----PPAVTPPS 1623
Query: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440
G P G P S P SL + +P P + P
Sbjct: 1624 PEKGPATPAPKGTPTSPPVTPSSL---------KDSPTSPASVTCKMGATVPQASKGLPA 1674
Query: 441 HHGPPPMDQYL-GSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPS------GQPPPPP 493
GP + + L P + + KG PP P PS G
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA 1734
Query: 494 SGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAA 553
PL P Q+ + S S P + +T T +A +P + +AA
Sbjct: 1735 PAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAP 1794
Query: 554 SPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPP 588
SP P +PL P P LPP P P
Sbjct: 1795 SP--------PVSLPLAPSPVPTLPPKQQFLPSSP 1821
Score = 37.0 bits (84), Expect = 0.056
Identities = 42/144 (29%), Positives = 55/144 (38%), Gaps = 24/144 (16%)
Query: 487 GQPPPPPSGPLPPWQQQ-----QQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS- 540
GQP P P P QQ Q P P PS+ ++ +P+ Q+++ T GT
Sbjct: 39 GQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPE 98
Query: 541 --------IPPWQQQQAAAAASPG-APQMQGNP-TMVPL------PPGVQ--PPLPPGAP 582
I P A A ASP AP ++G P + PL P VQ PP
Sbjct: 99 APTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLL 158
Query: 583 PPPPPPPPGSAGMMIPPRGGDGPS 606
PP +G +I PS
Sbjct: 159 TSPPSVAVAESGSVITLSAPIAPS 182
Score = 33.5 bits (75), Expect = 0.62
Identities = 55/238 (23%), Positives = 81/238 (34%), Gaps = 45/238 (18%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P P++ + GP +T AP P P + S P P ES+ +
Sbjct: 1718 PDPSAKNGSKGPLSTV---APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774
Query: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG 443
+F LP P + + P P P P+ P P
Sbjct: 1775 AA----------AFEKVLPK--------PESASVSAAPSP---PVSLPLAPSPVPT---- 1809
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
PP Q+L S+P G+ K + P ++P PP P SG +P Q
Sbjct: 1810 LPPKQQFLPSSP---GLVLESPSKPLAPADEDELLPLIPPEPI-------SGGVP---FQ 1856
Query: 504 QQQPPPPPPPSSSMASSTPLPWQ----QNTTTTTTSAGTGSIPPWQQQQAAAAASPGA 557
P P S+ + TP Q N + T S S+P ++Q + A + A
Sbjct: 1857 SVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQA 1914
Score = 29.6 bits (65), Expect = 8.9
Identities = 32/115 (27%), Positives = 44/115 (38%), Gaps = 21/115 (18%)
Query: 511 PPPSSSMASSTPLPWQQNTTTTTTSA----GTGSIPPWQQ--QQAAAAASPGAPQMQGNP 564
P S+ A P + +T TTT++ GT S+ P ++ P P N
Sbjct: 649 PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENC 708
Query: 565 TMVPLPPGVQPPLP--------PGAPPPPPPPPPGSAGMMIPP--RGGDGPSHES 609
+ P P PL P + P P PP G+ PP + DG SH S
Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGT-----PPGTKKVDGISHTS 758
>gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7B
[Homo sapiens]
Length = 319
Score = 100 bits (248), Expect = 5e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7
[Homo sapiens]
Length = 325
Score = 100 bits (248), Expect = 5e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6
[Homo sapiens]
Length = 319
Score = 100 bits (248), Expect = 5e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5
[Homo sapiens]
Length = 341
Score = 100 bits (248), Expect = 5e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 99.0 bits (245), Expect = 1e-20
Identities = 88/253 (34%), Positives = 97/253 (38%), Gaps = 64/253 (25%)
Query: 364 SRPPWMNSGPSESRPYHGMHGG----GPGGPGGGPHSFPH----PLPSLTGGHGGHPMQH 415
SR + G R + GG GP GPGG P FP P P L G P
Sbjct: 193 SRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL-----GPPGPP 247
Query: 416 NPNGPPPPWMQPPPP---PMNQGPHPPGHHGPPPM--DQYLGSTPVGSGVYRLHQGKGMM 470
P GPPPP PPP P N+G PP PP + Q G P+G L G
Sbjct: 248 GPPGPPPPGQVLPPPLAGPPNRGDRPP----PPVLFPGQPFGQPPLGP----LPPGP--- 296
Query: 471 PPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTT 530
PPP G PPP PPP Q PPPP GP PP +PP P P ++A LP
Sbjct: 297 PPPVPGYGPPPGPPPPQQGPPPPPGPFPP------RPPGPLGPPLTLAPPPHLPG----- 345
Query: 531 TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP--- 587
PP A P AP + NP P P P PPP
Sbjct: 346 -----------PP-------PGAPPPAPHV--NPAFFPPPTNSGMPTSDSRGPPPTDPYG 385
Query: 588 -PPPGSAGMMIPP 599
PPP G PP
Sbjct: 386 RPPPYDRGDYGPP 398
Score = 92.4 bits (228), Expect = 1e-18
Identities = 82/246 (33%), Positives = 87/246 (35%), Gaps = 60/246 (24%)
Query: 382 MHGGGPGGPGGGPHSFPHP--------LPSLTGGHGGHPMQHNPNGPPPPW---MQPPPP 430
M G G GP GG P P G P P GPPPP+ PP P
Sbjct: 180 MSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239
Query: 431 PMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQP- 489
P+ P PPG GPPP Q L G PP G PPPP GQP
Sbjct: 240 PLGP-PGPPGPPGPPPPGQVLPPPLAG--------------PPNRGDRPPPPVLFPGQPF 284
Query: 490 PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQA 549
PP GPLPP PPPP P P P Q G PP
Sbjct: 285 GQPPLGPLPPG-------PPPPVPGYGPPPGPPPPQQ------------GPPPP------ 319
Query: 550 AAAASPGAPQMQGNP-TMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDG-PSH 607
P P G P T+ P PP PG PP PPP P PP G P+
Sbjct: 320 PGPFPPRPPGPLGPPLTLAP------PPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTS 373
Query: 608 ESEDFP 613
+S P
Sbjct: 374 DSRGPP 379
Score = 82.8 bits (203), Expect = 9e-16
Identities = 64/188 (34%), Positives = 73/188 (38%), Gaps = 23/188 (12%)
Query: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380
G P P G T P PL P P P PPP ++ + PP P +
Sbjct: 224 GGPPPPFPAGQT--PPRPPLGP-PGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP 280
Query: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440
G G P G P P P+P G+G P GPPPP PPPPP P PPG
Sbjct: 281 GQPFGQP-PLGPLPPGPPPPVP----GYG------PPPGPPPPQQGPPPPPGPFPPRPPG 329
Query: 441 HHGPP---PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP------PPPPPPSGQPPP 491
GPP +L P G+ H PPP MP PPP P G+PPP
Sbjct: 330 PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
Query: 492 PPSGPLPP 499
G P
Sbjct: 390 YDRGDYGP 397
Score = 74.3 bits (181), Expect = 3e-13
Identities = 67/214 (31%), Positives = 76/214 (35%), Gaps = 55/214 (25%)
Query: 428 PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSG 487
PP ++ P G G ++ G+ P G P P G PPPP P+G
Sbjct: 188 PPGGSSRAAFPQGGRG---RGRFPGAVPGGDRF-----------PGPAGPGGPPPPFPAG 233
Query: 488 QPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ 546
Q PP PP GP P P PP PP PL N G PP
Sbjct: 234 QTPPRPPLGPPGP-------PGPPGPPPPGQVLPPPLAGPPNR---------GDRPP--- 274
Query: 547 QQAAAAASPGAPQMQGNPTMVPLPPGVQPPLP------------PGAPPPPPPPPPGSAG 594
PG P G P + PLPPG PP+P G PPPP P PP G
Sbjct: 275 ---PPVLFPGQPF--GQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG 329
Query: 595 MMIPPRGGDGPSHESEDFPRPLVTLPGRQPQQRP 628
+ PP P H P P P P P
Sbjct: 330 PLGPPLTLAPPPH----LPGPPPGAPPPAPHVNP 359
Score = 50.1 bits (118), Expect = 6e-06
Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 24/155 (15%)
Query: 321 GEAPVPASV--GSTSG-PATTPLASAPRPAAPANNPPP---------PSLMSTTQSRPPW 368
G+ P P + G G P PL P P P PPP P RPP
Sbjct: 270 GDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG 329
Query: 369 MNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP--PWMQ 426
P P + G PG P PH P P T + G P + GPPP P+ +
Sbjct: 330 PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPT--NSGMPTS-DSRGPPPTDPYGR 386
Query: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVY 461
PP P+ G +GPP + TP+ +
Sbjct: 387 PP-------PYDRGDYGPPGREMDTARTPLSEAEF 414
Score = 47.4 bits (111), Expect = 4e-05
Identities = 44/149 (29%), Positives = 57/149 (38%), Gaps = 20/149 (13%)
Query: 497 LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAA------ 550
L P ++ Q P P + S + ++ T + S + PP +AA
Sbjct: 143 LLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGR 202
Query: 551 -----AAASPGA-----PQMQGNPTMVPLPPGVQPPLPPGAPP-PPPPPPPGSAGMMIPP 599
A PG P G P P P G PP PP PP PP PP P G ++PP
Sbjct: 203 GRGRFPGAVPGGDRFPGPAGPGGPPP-PFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPP 261
Query: 600 RGGDGPSHESEDFPRPLVTLPGRQPQQRP 628
P+ D P P V PG+ Q P
Sbjct: 262 PLAGPPNR--GDRPPPPVLFPGQPFGQPP 288
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 99.0 bits (245), Expect = 1e-20
Identities = 77/216 (35%), Positives = 86/216 (39%), Gaps = 25/216 (11%)
Query: 316 LMAELGEA-PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS 374
+++ LG P P S P P A P P PPPP PP + P
Sbjct: 224 VVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGT-PG 282
Query: 375 ESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ 434
P HG P PGG PH P HG H + H GPP QPPP P
Sbjct: 283 AGHPGHGHSHPHPFPPGGMPH--PGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPG 340
Query: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP----SGQPP 490
PHP GPPPM P GS + H G P PP GM PPP P +G P
Sbjct: 341 MPHP----GPPPMGMPPRGPPFGSPMG--HPG----PMPPHGMRGPPPLMPPHGYTGPPR 390
Query: 491 PPP----SGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
PPP GPLPP + P PP PP + P
Sbjct: 391 PPPYGYQRGPLPP---PRPTPRPPVPPRGPLRGPLP 423
Score = 70.5 bits (171), Expect = 5e-12
Identities = 62/187 (33%), Positives = 69/187 (36%), Gaps = 30/187 (16%)
Query: 462 RLHQGKGMMPPPPM-----------GMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPP 509
R HQ PPPP G+ PP PPP PPP PP G LPP PPP
Sbjct: 206 RPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPP 265
Query: 510 PPP------PSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563
PP P S+ P ++ G P Q Q A P G+
Sbjct: 266 MPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLA----HHGPHGLGH 321
Query: 564 PTMVPLPPGVQPP--LPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPG 621
P P G QPP PPG P P PPP M +PPRG S P P + G
Sbjct: 322 PHAGPPGSGGQPPPRPPPGMPHPGPPP------MGMPPRGPPFGSPMGHPGPMPPHGMRG 375
Query: 622 RQPQQRP 628
P P
Sbjct: 376 PPPLMPP 382
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 98.6 bits (244), Expect = 2e-20
Identities = 90/264 (34%), Positives = 105/264 (39%), Gaps = 41/264 (15%)
Query: 346 PAAPANNP----PPPSLMSTTQSRPPWMNS---GPSESRPYHGMHGGGPGGPGG-GPHSF 397
P+ PA P PPP LM+ RPP S P P M GP G GP
Sbjct: 221 PSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQL 280
Query: 398 PHPLPSLTGGHGGHPMQHNPNG---PPPPWMQPPPP---PMNQGPHPP--GHHGPPPMDQ 449
P P P G H P+ H P PP P + PP P P G HPP G H P P
Sbjct: 281 PPPAP---GVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAP--- 334
Query: 450 YLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPP---PPPSGQPPPPPSGPLPPWQQQQQQ 506
G P GV+ G+ PP P G+ PP P PPPS P G P Q
Sbjct: 335 --GVHPPAPGVHP--PAPGVHPPAP-GVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQ 389
Query: 507 PPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTM 566
P PP+ M P Q ++ G PP ++PG PT
Sbjct: 390 APGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPP-----GVHPSNPGVHP----PT- 439
Query: 567 VPLPPGVQPPLPPGAPPPPPPPPP 590
P+PP ++PPLP P PPPPP
Sbjct: 440 -PMPPMLRPPLPSEGPGNIPPPPP 462
Score = 82.0 bits (201), Expect = 2e-15
Identities = 74/239 (30%), Positives = 87/239 (36%), Gaps = 32/239 (13%)
Query: 393 GPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLG 452
GP P P L G P PPPP P PP GP P G GPP +
Sbjct: 226 GPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAP 285
Query: 453 ST--------PVGSGVYRLHQGKGMMPPPPMGMMPPPP---PPPSGQPPPPPSGPLPPWQ 501
P SGV+ G+ PP P G+ PP P PP SG PP P G PP
Sbjct: 286 GVHPPAPVVHPPASGVH--PPAPGVHPPAP-GVHPPAPGVHPPTSGVHPPAP-GVHPPAP 341
Query: 502 QQQQQPPPPPPPSSSMASSTP-LPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQM 560
P PP+ + P + + + G P QA P
Sbjct: 342 GVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMH 401
Query: 561 QGNPTMVPLPPGVQP------PLPPGAPP------PPPPPPPGSAGMMIPPRGGDGPSH 607
P + P PPGV P P PPG P PP P PP M+ PP +GP +
Sbjct: 402 PQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPP----MLRPPLPSEGPGN 456
Score = 75.9 bits (185), Expect = 1e-13
Identities = 68/211 (32%), Positives = 80/211 (37%), Gaps = 29/211 (13%)
Query: 420 PPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP 479
PP P P PP + P PP +G PP S +PPPP G +P
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPES----------------LPPPPPGGLP 260
Query: 480 PPPPPPSGQPPPPPSGP--LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAG 537
PP PP+G P P GP LPP P P P +S P P
Sbjct: 261 LPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPAS-GVHPPAPGVHPPAPGVHPPA 319
Query: 538 TGSIPPWQQQQAAAAASPGAPQMQ-GNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMM 596
G PP + P AP + P + P PGV PP P PP P PP SAG+
Sbjct: 320 PGVHPP------TSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVH 373
Query: 597 IPPRGGDGPSHESEDFPRPLV--TLPGRQPQ 625
P G P+ + P V PG PQ
Sbjct: 374 -PQAPGVHPAAPAVHPQAPGVHPPAPGMHPQ 403
Score = 74.3 bits (181), Expect = 3e-13
Identities = 67/209 (32%), Positives = 79/209 (37%), Gaps = 38/209 (18%)
Query: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQS-RPPWMN---SGPSESR 377
+ P PA P P AS P AP +PP P + PP P
Sbjct: 279 QLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHP 338
Query: 378 PYHGMHGGGPGGPGGGPHSFP-----HPLPSL------TGGHGGHPMQHNPNGPPPPWMQ 426
P G+H PG P P HP PS G H P H P P +
Sbjct: 339 PAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVH----PQAPGVH 394
Query: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPS 486
PP P M+ P PG H PP G P GV+ Q G+ P P G+ PP P PP
Sbjct: 395 PPAPGMH--PQAPGVHPQPP-----GVHPSAPGVHP--QPPGVHPSNP-GVHPPTPMPPM 444
Query: 487 GQPPPPPSGPLPPWQQQQQQPPPPPPPSS 515
+PP P GP PPPPP++
Sbjct: 445 LRPPLPSEGP---------GNIPPPPPTN 464
Score = 73.9 bits (180), Expect = 4e-13
Identities = 55/182 (30%), Positives = 72/182 (39%), Gaps = 22/182 (12%)
Query: 425 MQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG-MMPPPPP 483
M+ PP P + PPG PPP P+ +G + P PP+ +PPPPP
Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPP--------PLMNG---------LPPRPPLPESLPPPPP 256
Query: 484 PPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPP 543
PP PP+GP P PP PPP+ + P+ + + G P
Sbjct: 257 GGLPLPPMPPTGPAP---SGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAP 313
Query: 544 WQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGD 603
A P + P + P PGV PP PG PP P P + G+ PP G
Sbjct: 314 GVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPP-APGVHPPAPGVHPPAPGVHPPPSAGV 372
Query: 604 GP 605
P
Sbjct: 373 HP 374
Score = 49.7 bits (117), Expect = 8e-06
Identities = 39/126 (30%), Positives = 50/126 (39%), Gaps = 26/126 (20%)
Query: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380
G P P++ P P A A P AP +PP P + + P ++ P
Sbjct: 363 GVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGM----HPQAPGVHPQPP------ 412
Query: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440
G+H PG HP P G H +P H P P PP ++PP P G PP
Sbjct: 413 GVHPSAPG---------VHPQP--PGVHPSNPGVHPPT-PMPPMLRPPLPSEGPGNIPP- 459
Query: 441 HHGPPP 446
PPP
Sbjct: 460 ---PPP 462
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/154 (27%), Positives = 48/154 (31%), Gaps = 52/154 (33%)
Query: 470 MPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNT 529
M PP P PP +PPPP LPP + PPPPP PLP
Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPP------GGLPLP----- 262
Query: 530 TTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP-GVQPPLPPGAP--PPPP 586
P+PP G P PPG P PPP
Sbjct: 263 --------------------------------------PMPPTGPAPSGPPGPPQLPPPA 284
Query: 587 PPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLP 620
P A ++ PP G P P P V P
Sbjct: 285 PGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPP 318
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 98.2 bits (243), Expect = 2e-20
Identities = 74/225 (32%), Positives = 84/225 (37%), Gaps = 46/225 (20%)
Query: 410 GHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG----PPPMDQYLGSTPVGSGVYR--- 462
G P P G P PPPP QGP P G + PPP + G P G +
Sbjct: 34 GKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPP 93
Query: 463 LHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPP------PPSSS 516
H GK PPP G PPP G+P PP P Q +PPPPP PP
Sbjct: 94 PHPGKPERPPPQGGNQSQGTPPPPGKPERPP----PQGGNQSHRPPPPPGKPERPPPQGG 149
Query: 517 MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASP-----GAPQMQGNPTMVPLPP 571
S P P PP + ++ +A SP G PQ +GN P PP
Sbjct: 150 NQSQGPPPHPGKPEGP---------PPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPP 200
Query: 572 GV------------QPPLPPGAPPPPPPPPPGSAGMMIPPRGGDG 604
G QP PP P PPPPP PPR G
Sbjct: 201 GKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGR---PPRPAQG 242
Score = 77.8 bits (190), Expect = 3e-14
Identities = 67/202 (33%), Positives = 76/202 (37%), Gaps = 42/202 (20%)
Query: 345 RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSL 404
RP P P P QS+ P G E RP G G G PH P
Sbjct: 49 RPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQG----GNQSQGPPPHPGKPERPPP 104
Query: 405 TGGH---GGHPMQHNPNGPPPPW----MQPPPPP------------MNQGP--HPPGHHG 443
GG+ G P P PPP +PPPPP +QGP HP G
Sbjct: 105 QGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEG 164
Query: 444 PPPMD---QYLGSTPVGS--GVYRLHQGKGMMPPPPMGMMPPPPP---------PPSGQP 489
PPP + +P G G + K PPPP PPP PP+G+P
Sbjct: 165 PPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKP 224
Query: 490 ---PPPPSGPLPPWQQQQQQPP 508
PPPP G PP Q QQPP
Sbjct: 225 QGPPPPPQGGRPPRPAQGQQPP 246
Score = 69.7 bits (169), Expect = 8e-12
Identities = 59/203 (29%), Positives = 70/203 (34%), Gaps = 39/203 (19%)
Query: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNP------------PPPSLMSTTQSRPPWM 369
+ P P + GP P RP N PPP + +Q PP
Sbjct: 58 QGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPP 117
Query: 370 NSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP------- 422
P P G P P G P P + + G HP + P GPPP
Sbjct: 118 GK-PERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGK--PEGPPPQEGNKSR 174
Query: 423 ----PWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM 478
P +P PP +G P GPPP + G P G G P P
Sbjct: 175 SARSPPGKPQGPPQQEGNKP---QGPPPPGKPQGPPPAG--------GNPQQPQAPPAGK 223
Query: 479 P--PPPPPPSGQPPPPPSGPLPP 499
P PPPPP G+PP P G PP
Sbjct: 224 PQGPPPPPQGGRPPRPAQGQQPP 246
Score = 67.0 bits (162), Expect = 5e-11
Identities = 61/181 (33%), Positives = 68/181 (37%), Gaps = 31/181 (17%)
Query: 463 LHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPP------PPSSS 516
L GK P G P PPPP G+P PP P Q Q PPPPP PP
Sbjct: 31 LISGKPEGRRPQGGNQPQRPPPPPGKPQGPP----PQGGNQSQGPPPPPGKPEGRPPQGG 86
Query: 517 MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQ-- 574
S P P G PP Q S G P G P P G Q
Sbjct: 87 NQSQGPPP----------HPGKPERPPPQ----GGNQSQGTPPPPGKPERPPPQGGNQSH 132
Query: 575 -PPLPPGAPPPPPPPPPGSAGMMIPPRGG--DGPSHESEDFPRPLVTLPGRQPQQRPWWT 631
PP PPG P PPP G+ PP G +GP + + R + PG+ PQ P
Sbjct: 133 RPPPPPG-KPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGK-PQGPPQQE 190
Query: 632 G 632
G
Sbjct: 191 G 191
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 97.4 bits (241), Expect = 3e-20
Identities = 93/290 (32%), Positives = 99/290 (34%), Gaps = 61/290 (21%)
Query: 349 PANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGH 408
P PPPP + RPP S+ P GP GG P P P G
Sbjct: 47 PQRTPPPPG---KPEGRPP-QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQ 102
Query: 409 ---GGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQ 465
GG+ Q P P P PPP NQ PP G P G P G +Q
Sbjct: 103 PPQGGNQSQGPPPRPGKP-EGPPPQGGNQSQGPPPRPGKPE-----GPPPQGG-----NQ 151
Query: 466 GKGMMPPPPMGMMPPPPPPPSG---QPPPP----PSGPLPPWQQQQQQPPPPP------P 512
+G PPP P PPP G Q PPP P GP P Q Q PPP P P
Sbjct: 152 SQG---PPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 208
Query: 513 PSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASP------GAPQMQGNPTM 566
P S P P G PP Q P G P +GN
Sbjct: 209 PQGGNQSQGPPP----------RPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQ 258
Query: 567 VPLPPG-----------VQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDGP 605
P PPG Q PLPP A P PPPP G P G P
Sbjct: 259 RPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308
Score = 90.1 bits (222), Expect = 6e-18
Identities = 74/232 (31%), Positives = 83/232 (35%), Gaps = 48/232 (20%)
Query: 296 RPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPP- 354
RPG P+ + + E P P + GP PRP P PP
Sbjct: 95 RPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP-------PRPGKPEGPPPQ 147
Query: 355 -------PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGG 407
PP + PP S+ P H GP GG P P P G
Sbjct: 148 GGNQSQGPPPRPGKPEGPPP-QGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG 206
Query: 408 ---HGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464
GG+ Q GPPP +P PP G P GPPP H
Sbjct: 207 PPPQGGNQSQ----GPPPRPGKPEGPPSQGGNKP---QGPPP-----------------H 242
Query: 465 QGKGMMPPPPMGMMPPPPPPPSG-QPPPPPSG----PLPPWQQQQQQPPPPP 511
GK PPP G P PPPP Q PPPP G PLPP + Q PPPPP
Sbjct: 243 PGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPP 294
Score = 84.3 bits (207), Expect = 3e-16
Identities = 97/335 (28%), Positives = 113/335 (33%), Gaps = 78/335 (23%)
Query: 336 ATTPLASAPRPAAPANNPPPPSLMS-TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGP 394
A L+SA + PS++S + R P + P + P G G P P GG
Sbjct: 9 ALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRP--PQGGN 66
Query: 395 HSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ-----PPPPPMNQGPHPPGHH---GPPP 446
S G P P GPPP PP P +G P G + GPPP
Sbjct: 67 QS-----------QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPP 115
Query: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP--PPPPPPSGQPPPP------------ 492
GK PPP G PPP P + PPP
Sbjct: 116 -----------------RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR 158
Query: 493 ---PSGPLPPWQQQQQQPPP------PPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI-P 542
P GP P Q Q PPP PPP S P P G S P
Sbjct: 159 PGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 218
Query: 543 PWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPP--LPPGAPPPP-----PPPPPGSAGM 595
P + + S G + QG P P G P P PPPP PPPP G+
Sbjct: 219 PPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQ 278
Query: 596 MIPPRGG--DGPSHESEDFPRPLVTLPGRQPQQRP 628
+PP G GP P P P R PQ +P
Sbjct: 279 PLPPPAGKPQGPP------PPPQGGRPHRPPQGQP 307
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 95.1 bits (235), Expect = 2e-19
Identities = 95/333 (28%), Positives = 120/333 (36%), Gaps = 68/333 (20%)
Query: 298 GDPQSAQDKARMDKEYLSLMAE--LGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPP 355
G PQ D +R L M L + P + ST ++ P P AN PP
Sbjct: 132 GRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPT 191
Query: 356 PSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQH 415
P M ++++ P + P P +H G G P P P ++ G G +
Sbjct: 192 PLPMHSSKA-PAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAP 250
Query: 416 NPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM 475
PPPP+ QPP P GP P + P + Q S LH+ P P
Sbjct: 251 ----PPPPYRQPPGVP--NGPSSPTNESAPELPQRHNS---------LHR---KTPGPVR 292
Query: 476 GMMPPPPPPPS-----GQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTT 530
G+ PPPP S +PPPP P + PPPPPP + A P P
Sbjct: 293 GLAPPPPTSASPSLLSNRPPPPARDP----PSRGAAPPPPPPVIRNGARDAPPP------ 342
Query: 531 TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPP- 589
PP + + S G P PP P P PPPPPPPP
Sbjct: 343 -----------PPPYRMHGSEPPSRGKPP----------PP---PSRTPAGPPPPPPPPL 378
Query: 590 -PGSAGMMIPPRG--GDGPS----HESEDFPRP 615
G + R D S H EDFP P
Sbjct: 379 RNGHRDSITTVRSFLDDFESKYSFHPVEDFPAP 411
Score = 36.2 bits (82), Expect = 0.095
Identities = 12/15 (80%), Positives = 13/15 (86%)
Query: 478 MPPPPPPPSGQPPPP 492
+PPPPPPP G PPPP
Sbjct: 3 IPPPPPPPPGPPPPP 17
Score = 33.1 bits (74), Expect = 0.80
Identities = 13/20 (65%), Positives = 15/20 (75%), Gaps = 2/20 (10%)
Query: 475 MGMMPPPPPPPSGQPPPPPS 494
M + PPPPPPP PPPPP+
Sbjct: 1 MPIPPPPPPPPG--PPPPPT 18
Score = 33.1 bits (74), Expect = 0.80
Identities = 11/15 (73%), Positives = 12/15 (80%)
Query: 576 PLPPGAPPPPPPPPP 590
P+PP PPPP PPPP
Sbjct: 2 PIPPPPPPPPGPPPP 16
Score = 30.8 bits (68), Expect = 4.0
Identities = 15/32 (46%), Positives = 15/32 (46%), Gaps = 5/32 (15%)
Query: 478 MPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPP 509
MP PPPPP PPP P PP Q P
Sbjct: 1 MPIPPPPP-----PPPGPPPPPTFHQANTEQP 27
Score = 30.8 bits (68), Expect = 4.0
Identities = 12/19 (63%), Positives = 14/19 (73%), Gaps = 2/19 (10%)
Query: 567 VPLPPGVQPPLPPGAPPPP 585
+P+PP PP PPG PPPP
Sbjct: 1 MPIPP--PPPPPPGPPPPP 17
Score = 30.0 bits (66), Expect = 6.8
Identities = 12/16 (75%), Positives = 12/16 (75%), Gaps = 2/16 (12%)
Query: 575 PPLPPGAPPPPPPPPP 590
PP PP PPP PPPPP
Sbjct: 4 PPPPP--PPPGPPPPP 17
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 91.7 bits (226), Expect = 2e-18
Identities = 87/316 (27%), Positives = 111/316 (35%), Gaps = 122/316 (38%)
Query: 305 DKARMDKEYLSLMAELGEAPVPASVGSTSG---------------PATTPLASAPRPAAP 349
+K +M +E++ +LG + P ++ +G P + AS+P P+
Sbjct: 204 EKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFS 263
Query: 350 ANNPPPPSLMSTTQSRPPWMNSGPSE-SRPYHGMHGGGPGGPGGGPHSFP-HPLPSLTGG 407
+N PPP P+E S P G G GP P HP P+
Sbjct: 264 EDNLPPP----------------PAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA---- 303
Query: 408 HGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGK 467
P +P GP P + PP PP PP
Sbjct: 304 ----PPLGSPPGPKPGFAPPPAPP-------------PP--------------------- 325
Query: 468 GMMPPPPMGMMPPPPPPPSGQP--PPPPSGP-LPPWQQQQQQPPPPPPPSSSMASSTPLP 524
PPP +G+ PPPPP G P PPPPS P PP PPPPPPP++ + P P
Sbjct: 326 ---PPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPP 382
Query: 525 WQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPP 584
Q T G PP PP PP P P
Sbjct: 383 LSQPT---------GGAPP-------------------------------PPPPPPPPGP 402
Query: 585 PPPPPPGSAGM-MIPP 599
PPPP G+ G IPP
Sbjct: 403 PPPPFTGADGQPAIPP 418
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 91.7 bits (226), Expect = 2e-18
Identities = 91/298 (30%), Positives = 112/298 (37%), Gaps = 52/298 (17%)
Query: 297 PGDPQSAQDKARMDKE-YLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPP 355
P PQ A + +++ + E +P SV G T P+ P+P P + P P
Sbjct: 783 PSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQP 842
Query: 356 PSLMSTTQSRPPWMNSGPSESRP-YHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQ 414
P S PP +N S P H P P + P P P+ +
Sbjct: 843 PE-----HSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALP-PKPARPPA-VSPALT 895
Query: 415 HNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPP 474
P P PP M PP + + PP PP+ T + +Y L Q + + PP P
Sbjct: 896 QTPLLPQPP-MAQPPQVLLEDEEPPA----PPL------TSMQMQLY-LQQLQKVQPPTP 943
Query: 475 MGMMPPPPPPPSGQPPPP-PSGPLPPWQQQ-QQQPPPPPPPSSSMASSTPLPWQQNTTTT 532
+ P QPPPP P P P QQQ QQQPPPPPPP P P
Sbjct: 944 L----LPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQ-------PQP-------- 984
Query: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP-GVQPPLPPGAPPPPPPPP 589
PP QQ Q P P PP G QPP PP PPPP P
Sbjct: 985 ---------PPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP 1033
Score = 80.9 bits (198), Expect = 3e-15
Identities = 78/301 (25%), Positives = 100/301 (33%), Gaps = 58/301 (19%)
Query: 339 PLASAPRPAAPANNPPPPSLMST-----------TQSRPPWMNSGPSESRPYHGMHGGGP 387
P+A P+ PP P L S Q P + S +S+P
Sbjct: 904 PMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQP--------- 954
Query: 388 GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPM 447
P PLP +Q P PPPP QPPP +Q P P H P
Sbjct: 955 ----------PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQF 1004
Query: 448 DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQP 507
++ PPPP G PP PPP GQ PPPP P P Q Q
Sbjct: 1005 STHI-----------------QQPPPPQGQQPPHPPP--GQQPPPPQ-PAKPQQVIQHHH 1044
Query: 508 PP----PPPPSSSMASSTPLPWQ-QNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQG 562
P P S+ P P + + + T PP Q Q A +Q
Sbjct: 1045 SPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQP 1104
Query: 563 NPTMVPLPPGVQPPL---PPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTL 619
P +V + P+ P +P P PP + P P + D RP++
Sbjct: 1105 QPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRP 1164
Query: 620 P 620
P
Sbjct: 1165 P 1165
Score = 68.6 bits (166), Expect = 2e-11
Identities = 79/303 (26%), Positives = 94/303 (31%), Gaps = 68/303 (22%)
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGP 394
PA P P P P PPPP Q PP P S P P
Sbjct: 750 PAPVPQQPPPPPQQP---PPPPPPQQQQQPPPP----PPPPSMPQQAAPAMKSSPPPFIA 802
Query: 395 HSFPHPLPSLTG------GHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMD 448
P P L G GH P+ H P PP + P PP H PP ++
Sbjct: 803 TQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHL----------PQPPEHSTPPHLN 852
Query: 449 QYLGSTPVGSGVYRLHQGKGMMPPPPMGM---MPPPPPPPSGQPPPPPSGPLPPWQQQQQ 505
Q+ +P LH P P +PP P P P PL P
Sbjct: 853 QHAVVSPPA-----LHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLP------ 901
Query: 506 QPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT 565
QPP PP + P PP Q Q+Q
Sbjct: 902 QPPMAQPPQVLLEDEEP-----------------PAPPLTSMQMQLYLQ----QLQKVQP 940
Query: 566 MVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMI--------PPRGGDGPSHESEDFPRPLV 617
PL P V+ P PPP PPPP S + PP+ P + + PRP+
Sbjct: 941 PTPLLPSVKVQSQP--PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVH 998
Query: 618 TLP 620
P
Sbjct: 999 LQP 1001
Score = 67.8 bits (164), Expect = 3e-11
Identities = 52/142 (36%), Positives = 59/142 (41%), Gaps = 30/142 (21%)
Query: 464 HQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPL 523
HQ P P +P PPPP QPPPPP PP QQQQQPPPPPPP S + P
Sbjct: 743 HQQMQQAPAP----VPQQPPPPPQQPPPPP----PP--QQQQQPPPPPPPPSMPQQAAP- 791
Query: 524 PWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT---MVPLPPGVQPPLPPG 580
A S PP+ Q P P +P P+ QP LPP
Sbjct: 792 ------------AMKSSPPPFIATQ-VPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPH 838
Query: 581 APPPP---PPPPPGSAGMMIPP 599
P PP PP ++ PP
Sbjct: 839 LPQPPEHSTPPHLNQHAVVSPP 860
Score = 58.2 bits (139), Expect = 2e-08
Identities = 83/287 (28%), Positives = 95/287 (33%), Gaps = 70/287 (24%)
Query: 408 HGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHH--------GPPPMDQY----LGSTP 455
H H Q P P QPPPPP P PP PP M Q + S+P
Sbjct: 738 HHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSP 797
Query: 456 ---VGSGVYRLH-QGKGMMPPP-----------PMGMMPP--PPPPPSGQPP-------- 490
+ + V L Q G + P P +PP P PP PP
Sbjct: 798 PPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVV 857
Query: 491 -PP------PSGPLPPWQQQQQQPPPP--PPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541
PP P P P + PP P PP S + TPL Q
Sbjct: 858 SPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEE 917
Query: 542 PP------------WQQQQAAAAASPGAP----QMQGNPTMVPLP-PGVQPPL--PPGAP 582
PP QQ Q +P P Q Q P + P P P VQ L P P
Sbjct: 918 PPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPP 977
Query: 583 PPPPPPPPGSAGMMIPPRGGDGPSH-ESEDFPRPLVTLPGRQPQQRP 628
PPP P PP PPR P H + F + P Q QQ P
Sbjct: 978 PPPQPQPPPQQQHQPPPR----PVHLQPMQFSTHIQQPPPPQGQQPP 1020
Score = 48.9 bits (115), Expect = 1e-05
Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 21/109 (19%)
Query: 426 QPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP 485
QP PPP+ PHP P + TPV M PP + PPP PP
Sbjct: 212 QPNPPPVQATPHP----FPAVTPDLIVQTPV------------MTVVPPQPLQTPPPVPP 255
Query: 486 SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTT 534
QPPP P+ Q Q PP + + + + +TTT TT
Sbjct: 256 QPQPPPAPAP-----QPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299
Score = 38.5 bits (88), Expect = 0.019
Identities = 53/235 (22%), Positives = 76/235 (32%), Gaps = 54/235 (22%)
Query: 327 ASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG 386
A G ++ P TT ++ P+ P NPPP
Sbjct: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQAT--------------------------- 221
Query: 387 PGGPGGGPHSFPHPLPSLTGGHG------GHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440
PH FP P L P+Q P PP P QPPP P P P
Sbjct: 222 -------PHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQP--QPPPAP---APQPVQ 269
Query: 441 HHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPW 500
H P + +TP + + K P + P PPS PP P
Sbjct: 270 SHPP-----IIAATPQPVKTKKGVKRKADTTTPTT--IDPIHEPPS--LPPEPKTTKLGQ 320
Query: 501 QQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASP 555
+++ +P PP + P P + + + +G + ++ AA A P
Sbjct: 321 RRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWP 375
Score = 32.7 bits (73), Expect = 1.1
Identities = 58/283 (20%), Positives = 78/283 (27%), Gaps = 80/283 (28%)
Query: 345 RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSL 404
+P P PP PS+ Q +PP P P H P P F +
Sbjct: 953 QPPPPLPPPPHPSVQQQLQQQPP-PPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQP 1011
Query: 405 TGGHGGHPMQHNPNGPPPPWMQPPPPPM-----------NQGPHPPGHHGPPPMDQYLGS 453
G P H P G PP QP P P+ GH P + S
Sbjct: 1012 PPPQGQQP-PHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHS 1070
Query: 454 TPVGSGVYRLHQGK---------------GMMPPPPM--------------------GMM 478
+ HQ ++ P P+ +
Sbjct: 1071 PQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLR 1130
Query: 479 PPPPPPPSG-----------------------QPP----PPPSGPLPPWQQQQQQPPPPP 511
P PP P +PP PPP P +Q+Q+P P
Sbjct: 1131 PEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGA--PDKDKQKQEPKTPV 1188
Query: 512 PPSSSMASSTPLPWQ---QNTTTTTTSAGTGSIPPWQQQQAAA 551
P + W Q TT +S S ++Q + AA
Sbjct: 1189 APKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAA 1231
Score = 32.0 bits (71), Expect = 1.8
Identities = 37/146 (25%), Positives = 47/146 (32%), Gaps = 26/146 (17%)
Query: 483 PPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIP 542
P S P + P Q Q PPP +TP P+ T ++
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPP--------VQATPHPFPAVTPDLIVQTPVMTVV 242
Query: 543 PWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGG 602
P Q Q T P+PP QPP P AP P PP A P +
Sbjct: 243 PPQPLQ----------------TPPPVPPQPQPP-PAPAPQPVQSHPPIIAATPQPVKTK 285
Query: 603 DGPSHESEDFPRPLVTLPGRQPQQRP 628
G ++ D P P +P P
Sbjct: 286 KGVKRKA-DTTTPTTIDPIHEPPSLP 310
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 90.9 bits (224), Expect = 3e-18
Identities = 99/328 (30%), Positives = 121/328 (36%), Gaps = 77/328 (23%)
Query: 348 APANNPPPPSLMSTTQSRPPWMN------------------SGPSESRPYHGMHGGGPGG 389
AP PPPP S Q++ P N SGP+++ P PG
Sbjct: 1543 APPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGH 1602
Query: 390 PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH---PPGHHGPPP 446
H P P++ H PPPP PPP GPH P H
Sbjct: 1603 HVTPGHFLPSQNPTI------HHQTAAAVVPPPP-----PPPPAPGPHLVQQPNSHQQHS 1651
Query: 447 MDQYLGS----TPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQ 502
+ +G TP GS ++ G + PPPP PP P P PPP PS L Q
Sbjct: 1652 VAHVVGPVHAVTP-GSHIHSQTAGHHLPPPPP-----PPGPAPHHHPPPHPSTGLQGLQA 1705
Query: 503 QQQQ-------PPPPPPPSSSMAS--------STPLPWQQNTTTTTTSAGTGSIPPWQQQ 547
Q Q PPPPPPPSS +AS + P Q +SA ++PP+ Q
Sbjct: 1706 QHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHP-TVPPYPSQ 1764
Query: 548 QAAAAASPGAPQMQ--GNPTMVPLP---PGVQPPLPPGAPPPPPP---PPPGSAGMMIPP 599
PQ Q G PLP P +QP P P P P PGS + P
Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVAL---P 1821
Query: 600 RGGDGPSHESEDFPRPLVTLPGRQPQQR 627
G GP S +PG+ P R
Sbjct: 1822 HGVQGPQQAS--------PVPGQIPIHR 1841
Score = 61.2 bits (147), Expect = 3e-09
Identities = 70/240 (29%), Positives = 78/240 (32%), Gaps = 58/240 (24%)
Query: 338 TPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG----------- 386
T A P P P PP P Q +S P H + G
Sbjct: 1621 TAAAVVPPPPPP---PPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHL 1677
Query: 387 ---PGGPGGGPHSFPHPLPS--LTGGHGGHPMQHNPNGPPPPWMQPPPPPMN-------- 433
P PG PH P P PS L G H QH N PPP PPPPP +
Sbjct: 1678 PPPPPPPGPAPHHHPPPHPSTGLQGLQAQH--QHVVNSAPPP--PPPPPPSSVLASGHHT 1733
Query: 434 ---QGPHPPGHHGPPPM------------DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM 478
Q H P H GPP Q T +G G HQ G P P+ +
Sbjct: 1734 TSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQ--HQPSGTGPHCPLPVT 1791
Query: 479 PP----------PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528
P P P SG P P S LP Q QQ P P + P +Q N
Sbjct: 1792 GPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNN 1851
Score = 57.0 bits (136), Expect = 5e-08
Identities = 62/213 (29%), Positives = 74/213 (34%), Gaps = 58/213 (27%)
Query: 420 PPPPWMQPPPPPMNQGPHPPGHHG---PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG 476
PP P ++ PP + PH P HG P P Q LGS YR H + P +G
Sbjct: 1442 PPSPHLENPPK--SSTPHTPVQHGYLSPKPPSQQLGSP------YRPHHSQS----PQVG 1489
Query: 477 MMPPPPPP---PSGQPPP--------------PPSGPLPPWQQQQQQ---------PPPP 510
P P+ Q P PSG Q Q PPPP
Sbjct: 1490 TPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPP 1549
Query: 511 PPPSSS----------MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAA--ASPGAP 558
PPPSSS + L + T TS ++P QQ +PG
Sbjct: 1550 PPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHF 1609
Query: 559 QMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPG 591
NPT+ P PPPPPPP PG
Sbjct: 1610 LPSQNPTIHHQTAAAVVP-----PPPPPPPAPG 1637
Score = 46.6 bits (109), Expect = 7e-05
Identities = 37/121 (30%), Positives = 43/121 (35%), Gaps = 16/121 (13%)
Query: 482 PPPPSGQPPPPPSGPLPPWQQQQQQPPPP---------PPPSSSMASSTPLPWQQNTTTT 532
PP P + PP S P P Q P PP P S S TP Q
Sbjct: 1442 PPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTP----QREPQR 1497
Query: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGS 592
++P QQ + P Q + T Q L APPPPPPPPP S
Sbjct: 1498 NFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFN---QQSLNSTAPPPPPPPPPSS 1554
Query: 593 A 593
+
Sbjct: 1555 S 1555
Score = 32.0 bits (71), Expect = 1.8
Identities = 42/191 (21%), Positives = 57/191 (29%), Gaps = 32/191 (16%)
Query: 465 QGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPL- 523
Q KG P P + P P + +P P P Q + PP S S P
Sbjct: 1310 QAKG--PVPSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQ 1367
Query: 524 -----------PWQQNTTTTTTSAGTGSIPPWQQQQAA---AAASPGAP----------- 558
W + + G QQ+Q + A S P
Sbjct: 1368 AHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQ 1427
Query: 559 ---QMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRP 615
++ PT + PP PP + P P G PP G + P
Sbjct: 1428 LSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPK-PPSQQLGSPYRPHHSQSP 1486
Query: 616 LVTLPGRQPQQ 626
V P R+PQ+
Sbjct: 1487 QVGTPQREPQR 1497
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 90.9 bits (224), Expect = 3e-18
Identities = 99/328 (30%), Positives = 121/328 (36%), Gaps = 77/328 (23%)
Query: 348 APANNPPPPSLMSTTQSRPPWMN------------------SGPSESRPYHGMHGGGPGG 389
AP PPPP S Q++ P N SGP+++ P PG
Sbjct: 1543 APPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGH 1602
Query: 390 PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH---PPGHHGPPP 446
H P P++ H PPPP PPP GPH P H
Sbjct: 1603 HVTPGHFLPSQNPTI------HHQTAAAVVPPPP-----PPPPAPGPHLVQQPNSHQQHS 1651
Query: 447 MDQYLGS----TPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQ 502
+ +G TP GS ++ G + PPPP PP P P PPP PS L Q
Sbjct: 1652 VAHVVGPVHAVTP-GSHIHSQTAGHHLPPPPP-----PPGPAPHHHPPPHPSTGLQGLQA 1705
Query: 503 QQQQ-------PPPPPPPSSSMAS--------STPLPWQQNTTTTTTSAGTGSIPPWQQQ 547
Q Q PPPPPPPSS +AS + P Q +SA ++PP+ Q
Sbjct: 1706 QHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHP-TVPPYPSQ 1764
Query: 548 QAAAAASPGAPQMQ--GNPTMVPLP---PGVQPPLPPGAPPPPPP---PPPGSAGMMIPP 599
PQ Q G PLP P +QP P P P P PGS + P
Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVAL---P 1821
Query: 600 RGGDGPSHESEDFPRPLVTLPGRQPQQR 627
G GP S +PG+ P R
Sbjct: 1822 HGVQGPQQAS--------PVPGQIPIHR 1841
Score = 61.2 bits (147), Expect = 3e-09
Identities = 70/240 (29%), Positives = 78/240 (32%), Gaps = 58/240 (24%)
Query: 338 TPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG----------- 386
T A P P P PP P Q +S P H + G
Sbjct: 1621 TAAAVVPPPPPP---PPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHL 1677
Query: 387 ---PGGPGGGPHSFPHPLPS--LTGGHGGHPMQHNPNGPPPPWMQPPPPPMN-------- 433
P PG PH P P PS L G H QH N PPP PPPPP +
Sbjct: 1678 PPPPPPPGPAPHHHPPPHPSTGLQGLQAQH--QHVVNSAPPP--PPPPPPSSVLASGHHT 1733
Query: 434 ---QGPHPPGHHGPPPM------------DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM 478
Q H P H GPP Q T +G G HQ G P P+ +
Sbjct: 1734 TSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQ--HQPSGTGPHCPLPVT 1791
Query: 479 PP----------PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528
P P P SG P P S LP Q QQ P P + P +Q N
Sbjct: 1792 GPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNN 1851
Score = 57.0 bits (136), Expect = 5e-08
Identities = 62/213 (29%), Positives = 74/213 (34%), Gaps = 58/213 (27%)
Query: 420 PPPPWMQPPPPPMNQGPHPPGHHG---PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG 476
PP P ++ PP + PH P HG P P Q LGS YR H + P +G
Sbjct: 1442 PPSPHLENPPK--SSTPHTPVQHGYLSPKPPSQQLGSP------YRPHHSQS----PQVG 1489
Query: 477 MMPPPPPP---PSGQPPP--------------PPSGPLPPWQQQQQQ---------PPPP 510
P P+ Q P PSG Q Q PPPP
Sbjct: 1490 TPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPP 1549
Query: 511 PPPSSS----------MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAA--ASPGAP 558
PPPSSS + L + T TS ++P QQ +PG
Sbjct: 1550 PPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHF 1609
Query: 559 QMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPG 591
NPT+ P PPPPPPP PG
Sbjct: 1610 LPSQNPTIHHQTAAAVVP-----PPPPPPPAPG 1637
Score = 46.6 bits (109), Expect = 7e-05
Identities = 37/121 (30%), Positives = 43/121 (35%), Gaps = 16/121 (13%)
Query: 482 PPPPSGQPPPPPSGPLPPWQQQQQQPPPP---------PPPSSSMASSTPLPWQQNTTTT 532
PP P + PP S P P Q P PP P S S TP Q
Sbjct: 1442 PPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTP----QREPQR 1497
Query: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGS 592
++P QQ + P Q + T Q L APPPPPPPPP S
Sbjct: 1498 NFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFN---QQSLNSTAPPPPPPPPPSS 1554
Query: 593 A 593
+
Sbjct: 1555 S 1555
Score = 32.0 bits (71), Expect = 1.8
Identities = 42/191 (21%), Positives = 57/191 (29%), Gaps = 32/191 (16%)
Query: 465 QGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPL- 523
Q KG P P + P P + +P P P Q + PP S S P
Sbjct: 1310 QAKG--PVPSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQ 1367
Query: 524 -----------PWQQNTTTTTTSAGTGSIPPWQQQQAA---AAASPGAP----------- 558
W + + G QQ+Q + A S P
Sbjct: 1368 AHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQ 1427
Query: 559 ---QMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRP 615
++ PT + PP PP + P P G PP G + P
Sbjct: 1428 LSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPK-PPSQQLGSPYRPHHSQSP 1486
Query: 616 LVTLPGRQPQQ 626
V P R+PQ+
Sbjct: 1487 QVGTPQREPQR 1497
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 89.0 bits (219), Expect = 1e-17
Identities = 96/378 (25%), Positives = 133/378 (35%), Gaps = 75/378 (19%)
Query: 285 AGHIASDC-------KFQRPGDPQSAQDKARMD---KEYLSLMAELGEAPVPASVGSTSG 334
AGH+ S + + G KARM+ + Y SL+ L P + + S
Sbjct: 564 AGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQ 623
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGP 394
P+ P P P PPPP +QS P + P +
Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAP-----SAGSAAPMFVKYSTITRLQNASQ 678
Query: 395 HS---FPHPLPSLTGGHGGHP-MQHNPNG--PPPPWMQPPPPPMNQGPHPPGHHGPP--P 446
HS F P P + P + PNG PPPP PPPPP G P P
Sbjct: 679 HSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP---PPPPPPTPGSAMAQLKPAPCAP 735
Query: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPP-----PPSGQP------------ 489
+ P ++++ + PP P PPPPP PP P
Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQVAPPTP----PPPPPIPAPLPPQAPPKPLVTIPAPTST 791
Query: 490 -----------PPPPSGPLPPWQQQQQQPP---PPPPPSSSMASSTP-LPWQQNTTTTTT 534
PP P+ P+PP ++Q P PP PP+ + P LP QQ+
Sbjct: 792 KTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPP 851
Query: 535 SAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPG-------------A 581
+ +P +Q A+ P P + + P+P V P PP
Sbjct: 852 PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPV 911
Query: 582 PPPPPPPPPGSAGMMIPP 599
P P PPPP + ++ PP
Sbjct: 912 PSPDFPPPPPESSLVFPP 929
Score = 71.2 bits (173), Expect = 3e-12
Identities = 102/399 (25%), Positives = 130/399 (32%), Gaps = 98/399 (24%)
Query: 315 SLMAELGEAPVPASVGSTSGPA-------------TTPLASAPRPAAPANNPPP------ 355
S MA+L AP S+ S P P P P PA PP
Sbjct: 723 SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPL 782
Query: 356 ---PSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGG----GPHSFPHPLPSLTGGH 408
P+ ST P + P P P P P + P P+P T
Sbjct: 783 VTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPT--- 839
Query: 409 GGHPMQHNPNGPPPPWMQPPPPPM-----NQGPHPPGHHGPPPMD-QYLGSTPVGSGVYR 462
P Q + PPP P P + +Q P PP PP M+ Q L P
Sbjct: 840 --LPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT---PPAMESQPLKPVPANVAPQS 894
Query: 463 LHQGKG---------------MMPPPPMGMM--PPPPPPPSGQPPPPPSGPLPPWQQQQQ 505
K PPPP + PPPPP P PPPPP P +
Sbjct: 895 PPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG 954
Query: 506 QPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT 565
P +SS P P Q ++ +S+G P + + + P G+P+
Sbjct: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPS 1014
Query: 566 MVPLPPGVQPPLP----------PG----------AP-------------PPPP-----P 587
LPP PP P PG AP P PP P
Sbjct: 1015 KETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFP 1074
Query: 588 PPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQPQQ 626
PPP + +PP + P+ S + P V + QPQQ
Sbjct: 1075 PPPPETELPLPPI--EIPAVFSGN-TSPKVAVVNPQPQQ 1110
Score = 46.6 bits (109), Expect = 7e-05
Identities = 77/365 (21%), Positives = 95/365 (26%), Gaps = 118/365 (32%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNP-----------PPPSLMSTTQS-------- 364
PVP + + PA+ S P P P P PPPS +S S
Sbjct: 809 PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ 868
Query: 365 -----RPPWMNSGPSESRPYHGMHGGGPG---GPGGGPHSFPHPLPSLTGGHGGHPMQHN 416
PP M S P + P + P P P S P P P +
Sbjct: 869 FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP 928
Query: 417 PNGPPPPWMQPPPPPMNQGPHP---------------PGHHGPPPMDQYLGSTPVGSGVY 461
P P P PPPPP P P PG PPP Q S SG
Sbjct: 929 PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAE 988
Query: 462 RLHQ---------------------GKGMMPPPPMGMMP--------------------- 479
K +PPP P
Sbjct: 989 HPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSA 1048
Query: 480 ----------------PPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPL 523
P PP S PPPPP LP PP P+ +++P
Sbjct: 1049 KAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP--------LPPIEIPAVFSGNTSP- 1099
Query: 524 PWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPP 583
+ W + A P P+ + + QP + P
Sbjct: 1100 ---------KVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQ 1150
Query: 584 PPPPP 588
P P
Sbjct: 1151 VPTSP 1155
Score = 45.4 bits (106), Expect = 2e-04
Identities = 26/68 (38%), Positives = 28/68 (41%), Gaps = 8/68 (11%)
Query: 538 TGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMI 597
T +PP Q P P+ PLPP PP PP PPPPPPPPP
Sbjct: 603 TSLVPPLSPQPKIVT-----PYTASQPSP-PLPP--PPPPPPPPPPPPPPPPPPLPSQSA 654
Query: 598 PPRGGDGP 605
P G P
Sbjct: 655 PSAGSAAP 662
Score = 40.0 bits (92), Expect = 0.007
Identities = 62/287 (21%), Positives = 92/287 (32%), Gaps = 41/287 (14%)
Query: 297 PGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPP- 355
P P + + K + + + + P P S P +P+ + P P P +P P
Sbjct: 892 PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPD 951
Query: 356 ----PSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLT-GGHGG 410
P ++ S P P+ R G P S + T G
Sbjct: 952 KSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESG 1011
Query: 411 HPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQ--YLGSTPVGSGVYRLHQGKG 468
P + PPP P P +N G + P + Q PV SG +GK
Sbjct: 1012 SPSKET---LPPPAAPPKPGKLNLS----GVNLPGVLQQGCVSAKAPVLSG-----RGKD 1059
Query: 469 MM---PPPPMGMMPPPPPPPSGQPPPPPS----------------GPLPPWQQQQQQPPP 509
+ P PP PPPPP + P PP P P +
Sbjct: 1060 SVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKA 1119
Query: 510 PPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPG 556
PPP ST L + + T + +P +++ + PG
Sbjct: 1120 PPPTRPKRNDSTRLTQAEISEQPTMATVVPQVP--TSPKSSLSVQPG 1164
Score = 31.6 bits (70), Expect = 2.3
Identities = 21/67 (31%), Positives = 25/67 (37%), Gaps = 2/67 (2%)
Query: 545 QQQQAAAAASPGAPQMQGNPTMVPLPPGVQP--PLPPGAPPPPPPPPPGSAGMMIPPRGG 602
++ A S P P + P P V P P P PPPPPPP PP
Sbjct: 588 EESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP 647
Query: 603 DGPSHES 609
PS +
Sbjct: 648 PLPSQSA 654
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 87.4 bits (215), Expect = 4e-17
Identities = 91/330 (27%), Positives = 118/330 (35%), Gaps = 48/330 (14%)
Query: 322 EAPVPASVGSTSGPATTPLASAPR----PAAPANNPPPPSLMSTTQSRPPWMNSGPSESR 377
+ P S+ S++ P ++P S P P APA+ P P RPP + ++
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 378 PYHGMHGGGP---GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ 434
P G P P S P T Q P P PP +
Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353
Query: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS 494
P PP PP +T +GS L +P PP+ + PPP PP+
Sbjct: 354 LPSPPA---TPPSQ---ATTSLGSPT--LQATHSFLPSPPLSPLATPPPQA------PPA 399
Query: 495 GPLPPWQQQQQQPPPPP--PPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQA--- 549
LPP Q PP PP PP S +A TP P N S PP QA
Sbjct: 400 LALPPLQA----PPSPPASPPLSPLA--TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453
Query: 550 ----------AAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMM--- 596
A S P + P VP P PP+ P A PPP PPP +A +
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513
Query: 597 -IPPRGGDG-PSHESEDFPRPLVTLPGRQP 624
PP+ + + P P + PG+ P
Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPGQAP 543
Score = 82.4 bits (202), Expect = 1e-15
Identities = 80/303 (26%), Positives = 106/303 (34%), Gaps = 27/303 (8%)
Query: 333 SGPATTPLASAP----RPAAPANNPPPPSLMSTTQS-------RPPWMNSGPSESRPYHG 381
+ PA PL+S+P P+A + PP+L +T S P + PS S P
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSL 351
Query: 382 MHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQH-NPNGPPPPWMQPPP----PPMNQGP 436
P + P+L H P +P PPP Q PP PP+ P
Sbjct: 352 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP--QAPPALALPPLQAPP 409
Query: 437 HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPP----MGMMPPPPPPPSGQPPPP 492
PP PP+ +P +H + PPP PP PP P
Sbjct: 410 SPP---ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
Query: 493 PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAA 552
PS P Q PP PP S M+ S P Q PP A
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526
Query: 553 ASPGAPQMQGN-PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMM-IPPRGGDGPSHESE 610
P + P P P P+ P A PPP PP +A ++ +PP P+ ++
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586
Query: 611 DFP 613
P
Sbjct: 587 RRP 589
Score = 74.3 bits (181), Expect = 3e-13
Identities = 100/373 (26%), Positives = 128/373 (34%), Gaps = 81/373 (21%)
Query: 320 LGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMN-SGPSESRP 378
LG + A+ P +PLA+ P A PA PP + + PP + PS P
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428
Query: 379 -------YHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPP 431
P P P S P P P Q P+ PP PP PP
Sbjct: 429 NALAVHLLQAPFSPPPSPPVQAPFSPPASPP--VSPSATPPSQAPPSLAAPPLQVPPSPP 486
Query: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP----PPMGMMPPPPPPPSG 487
+ P P PP L + P+ +L + PP PP+ +P PP G
Sbjct: 487 ASP-PMSPSATPPPQAPPPLAAPPL-----QLAKPPPQAPPALATPPLQALPSPPASFPG 540
Query: 488 Q----------------PPP-------------PPSGPLPPWQQQQQQPP---------- 508
Q PPP PPS P P Q ++PP
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600
Query: 509 ----------PPPPPSSSMAS--STPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPG 556
PPPPPS S +S S P +++ T+T + AAA+ P
Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 660
Query: 557 APQMQGNPTMVPLPPGVQPPL----PPGAPPP-PPPPPPGSAGMMIPPRGGDGPSHESED 611
A +P P PPL PGAP P PP PGSA + +GP +
Sbjct: 661 AELAACHPAAWSRGPA--PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT-- 716
Query: 612 FPRPLVTLPGRQP 624
P P PG P
Sbjct: 717 -PAPGALDPGPSP 728
Score = 62.4 bits (150), Expect = 1e-09
Identities = 88/357 (24%), Positives = 110/357 (30%), Gaps = 102/357 (28%)
Query: 294 FQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNP 353
F P P + + SL A + P P+ TP AP P A
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA----A 507
Query: 354 PPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLP-SLTGGHGGHP 412
PP L PP + + P ++ P P SFP P S + P
Sbjct: 508 PPLQLAKPPPQAPPALATPPLQALP-------------SPPASFPGQAPFSPSASLPMSP 554
Query: 413 MQHNPNGPPP----PWMQ-PPPPPMN---QGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464
+ P PP P +Q PP PP + Q P P GP T V
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP--------DTSVSG------ 600
Query: 465 QGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPP--------------- 509
P + + P PPPPPS P SGP P
Sbjct: 601 ------PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 654
Query: 510 -PPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVP 568
PPP + +A+ P W + G PP A +PGAP +P
Sbjct: 655 ASPPPDAELAACHPAAWSR-----------GPAPP-----LAFRGAPGAP--------LP 690
Query: 569 LPPGVQPPL------------PPGAPPPP----PPPPPGSAGMMIPPRGGDGPSHES 609
PP P P A P P P P PG++G G G S S
Sbjct: 691 WPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 747
Score = 57.0 bits (136), Expect = 5e-08
Identities = 77/320 (24%), Positives = 96/320 (30%), Gaps = 21/320 (6%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPAN-NPPPPSLMSTTQSRPPWMNSGPSESRPYHGM 382
P PA + T PRPA A PP + S + PS +
Sbjct: 172 PSPAMARRSRAAGTE--VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229
Query: 383 HGGG---PGGPGGGPHSFPHPLPSLTG--GHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH 437
GGG P + P P+ +G G +P+ P P +Q PP P
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289
Query: 438 PPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPL 497
P+ +TP S + + P + P PP PS P
Sbjct: 290 KDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP- 348
Query: 498 PPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGA 557
Q P PP P S +S P Q T + S + Q A A P
Sbjct: 349 ---PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405
Query: 558 PQMQGNPTMVPLPPGVQP-PLPPGA--------PPPPPPPPPGSAGMMIPPRGGDGPSHE 608
P PL P P P P A P PPP PP A P PS
Sbjct: 406 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465
Query: 609 SEDFPRPLVTLPGRQPQQRP 628
P + P Q P
Sbjct: 466 PPSQAPPSLAAPPLQVPPSP 485
Score = 35.8 bits (81), Expect = 0.12
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 15/73 (20%)
Query: 571 PGVQPPLPPGAPPPPPPPPP------GSAGM-----MIPPRGGDGPSHESEDFPRPLVT- 618
PG+ P PPG+P PPPP P G+AG + GG G + E PR T
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 619 ---LPGRQPQQRP 628
R P RP
Sbjct: 82 SAGTSSRNPASRP 94
Score = 31.6 bits (70), Expect = 2.3
Identities = 41/184 (22%), Positives = 58/184 (31%), Gaps = 39/184 (21%)
Query: 436 PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM--------GMMPPPPPP--- 484
P PPG PPP PV R+ G + P+ G P P
Sbjct: 27 PRPPGSPRPPP--------PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 485 -----------PSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN----T 529
P+ +PP G P + P P P + ++ P P Q +
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
Query: 530 TTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMV----PLPPGVQPPLPPGAPPPP 585
T + G + P + +A A + G P+ G + LP AP
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
Query: 586 PPPP 589
P PP
Sbjct: 198 PRPP 201
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.134 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,709,381
Number of Sequences: 37866
Number of extensions: 4037285
Number of successful extensions: 122037
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1373
Number of HSP's successfully gapped in prelim test: 2087
Number of HSP's that attempted gapping in prelim test: 23200
Number of HSP's gapped (non-prelim): 33721
length of query: 638
length of database: 18,247,518
effective HSP length: 109
effective length of query: 529
effective length of database: 14,120,124
effective search space: 7469545596
effective search space used: 7469545596
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.