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Search of human proteins with 42544121
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42544121 vacuolar protein sorting 13C protein isoform 1A
[Homo sapiens]
(3710 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Hom... 7281 0.0
gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Hom... 7260 0.0
gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Hom... 7016 0.0
gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Hom... 6995 0.0
gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens] 1700 0.0
gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens] 1679 0.0
gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens] 1679 0.0
gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens] 1649 0.0
gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens] 234 2e-60
gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens] 234 2e-60
gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens] 107 2e-22
gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens] 107 2e-22
gi|119874215 vacuolar protein sorting 13B isoform 4 [Homo sapiens] 84 3e-15
gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens] 84 3e-15
gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens] 52 1e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 41 0.019
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 41 0.025
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 38 0.16
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 38 0.21
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 38 0.21
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 38 0.21
gi|55770834 centromere protein F [Homo sapiens] 38 0.21
gi|13699824 kinesin family member 11 [Homo sapiens] 37 0.28
gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [H... 37 0.48
gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [H... 36 0.62
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] 36 0.62
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] 36 0.62
gi|51988900 XPG-complementing protein [Homo sapiens] 36 0.81
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 35 1.4
gi|55749659 UHRF1 (ICBP90) binding protein 1-like isoform b [Hom... 35 1.8
>gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Homo
sapiens]
Length = 3710
Score = 7281 bits (18891), Expect = 0.0
Identities = 3710/3710 (100%), Positives = 3710/3710 (100%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180
ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG
Sbjct: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180
Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240
ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL
Sbjct: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240
Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300
TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID
Sbjct: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300
Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360
LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ
Sbjct: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360
Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420
LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS
Sbjct: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420
Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL 480
ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL
Sbjct: 421 ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL 480
Query: 481 PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY 540
PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY
Sbjct: 481 PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY 540
Query: 541 ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA 600
ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA
Sbjct: 541 ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA 600
Query: 601 VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ 660
VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ
Sbjct: 601 VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ 660
Query: 661 TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA 720
TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA
Sbjct: 661 TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA 720
Query: 721 EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK 780
EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK
Sbjct: 721 EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK 780
Query: 781 DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED 840
DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED
Sbjct: 781 DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED 840
Query: 841 GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG 900
GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG
Sbjct: 841 GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG 900
Query: 901 TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP 960
TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP
Sbjct: 901 TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP 960
Query: 961 SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ 1020
SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ
Sbjct: 961 SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ 1020
Query: 1021 QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ 1080
QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ
Sbjct: 1021 QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ 1080
Query: 1081 SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL 1140
SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL
Sbjct: 1081 SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL 1140
Query: 1141 NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI 1200
NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI
Sbjct: 1141 NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI 1200
Query: 1201 DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR 1260
DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR
Sbjct: 1201 DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR 1260
Query: 1261 TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL 1320
TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL
Sbjct: 1261 TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL 1320
Query: 1321 FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII 1380
FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII
Sbjct: 1321 FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII 1380
Query: 1381 NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD 1440
NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD
Sbjct: 1381 NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD 1440
Query: 1441 FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH 1500
FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH
Sbjct: 1441 FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH 1500
Query: 1501 LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA 1560
LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA
Sbjct: 1501 LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA 1560
Query: 1561 ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS 1620
ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS
Sbjct: 1561 ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS 1620
Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680
ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ
Sbjct: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680
Query: 1681 TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL 1740
TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL
Sbjct: 1681 TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL 1740
Query: 1741 IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ 1800
IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ
Sbjct: 1741 IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ 1800
Query: 1801 RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV 1860
RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV
Sbjct: 1801 RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV 1860
Query: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH 1920
RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH
Sbjct: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH 1920
Query: 1921 NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN 1980
NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN
Sbjct: 1921 NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN 1980
Query: 1981 NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP 2040
NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP
Sbjct: 1981 NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP 2040
Query: 2041 RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL 2100
RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL
Sbjct: 2041 RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL 2100
Query: 2101 EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK 2160
EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK
Sbjct: 2101 EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK 2160
Query: 2161 ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES 2220
ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES
Sbjct: 2161 ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES 2220
Query: 2221 FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT 2280
FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT
Sbjct: 2221 FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT 2280
Query: 2281 LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS 2340
LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS
Sbjct: 2281 LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS 2340
Query: 2341 GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR 2400
GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR
Sbjct: 2341 GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR 2400
Query: 2401 VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI 2460
VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI
Sbjct: 2401 VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI 2460
Query: 2461 PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN 2520
PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN
Sbjct: 2461 PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN 2520
Query: 2521 VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC 2580
VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC
Sbjct: 2521 VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC 2580
Query: 2581 MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL 2640
MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL
Sbjct: 2581 MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL 2640
Query: 2641 LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS 2700
LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS
Sbjct: 2641 LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS 2700
Query: 2701 DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF 2760
DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF
Sbjct: 2701 DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF 2760
Query: 2761 SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS 2820
SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS
Sbjct: 2761 SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS 2820
Query: 2821 RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV 2880
RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV
Sbjct: 2821 RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV 2880
Query: 2881 GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT 2940
GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT
Sbjct: 2881 GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT 2940
Query: 2941 PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY 3000
PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY
Sbjct: 2941 PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY 3000
Query: 3001 DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES 3060
DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES
Sbjct: 3001 DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES 3060
Query: 3061 KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN 3120
KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN
Sbjct: 3061 KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN 3120
Query: 3121 FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH 3180
FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH
Sbjct: 3121 FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH 3180
Query: 3181 PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL 3240
PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL
Sbjct: 3181 PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL 3240
Query: 3241 FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS 3300
FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS
Sbjct: 3241 FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS 3300
Query: 3301 GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR 3360
GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR
Sbjct: 3301 GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR 3360
Query: 3361 HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV 3420
HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV
Sbjct: 3361 HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV 3420
Query: 3421 RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG 3480
RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG
Sbjct: 3421 RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG 3480
Query: 3481 FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR 3540
FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR
Sbjct: 3481 FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR 3540
Query: 3541 AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKK 3600
AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKK
Sbjct: 3541 AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKK 3600
Query: 3601 TILMVTNRRVLCIKEVEILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSA 3660
TILMVTNRRVLCIKEVEILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSA
Sbjct: 3601 TILMVTNRRVLCIKEVEILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSA 3660
Query: 3661 NQGCVRKVYLKDTATAERACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS 3710
NQGCVRKVYLKDTATAERACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS
Sbjct: 3661 NQGCVRKVYLKDTATAERACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS 3710
>gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Homo
sapiens]
Length = 3753
Score = 7260 bits (18837), Expect = 0.0
Identities = 3710/3753 (98%), Positives = 3710/3753 (98%), Gaps = 43/3753 (1%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 ALQKAAEK-------------------------------------------DKPKEAKKD 137
ALQKAAEK DKPKEAKKD
Sbjct: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
Query: 138 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 197
TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN
Sbjct: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
Query: 198 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 257
EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS
Sbjct: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
Query: 258 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 317
ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY
Sbjct: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
Query: 318 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 377
KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK
Sbjct: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
Query: 378 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 437
VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK
Sbjct: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
Query: 438 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 497
KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS
Sbjct: 481 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 540
Query: 498 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 557
VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI
Sbjct: 541 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 600
Query: 558 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 617
GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT
Sbjct: 601 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 660
Query: 618 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 677
SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT
Sbjct: 661 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 720
Query: 678 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 737
FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI
Sbjct: 721 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 780
Query: 738 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 797
LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA
Sbjct: 781 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 840
Query: 798 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 857
QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA
Sbjct: 841 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 900
Query: 858 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 917
AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK
Sbjct: 901 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 960
Query: 918 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 977
KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF
Sbjct: 961 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 1020
Query: 978 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1037
SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD
Sbjct: 1021 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1080
Query: 1038 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1097
IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK
Sbjct: 1081 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1140
Query: 1098 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1157
TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL
Sbjct: 1141 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1200
Query: 1158 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1217
LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN
Sbjct: 1201 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1260
Query: 1218 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1277
AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP
Sbjct: 1261 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1320
Query: 1278 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1337
INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK
Sbjct: 1321 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1380
Query: 1338 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1397
VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK
Sbjct: 1381 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1440
Query: 1398 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1457
KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV
Sbjct: 1441 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1500
Query: 1458 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1517
TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF
Sbjct: 1501 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1560
Query: 1518 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1577
SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA
Sbjct: 1561 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1620
Query: 1578 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1637
DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA
Sbjct: 1621 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1680
Query: 1638 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1697
TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA
Sbjct: 1681 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1740
Query: 1698 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1757
ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL
Sbjct: 1741 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1800
Query: 1758 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1817
PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK
Sbjct: 1801 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1860
Query: 1818 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1877
GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ
Sbjct: 1861 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1920
Query: 1878 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1937
EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS
Sbjct: 1921 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1980
Query: 1938 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 1997
GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ
Sbjct: 1981 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 2040
Query: 1998 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2057
IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR
Sbjct: 2041 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2100
Query: 2058 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2117
PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP
Sbjct: 2101 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2160
Query: 2118 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2177
FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS
Sbjct: 2161 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2220
Query: 2178 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2237
PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV
Sbjct: 2221 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2280
Query: 2238 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2297
ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI
Sbjct: 2281 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2340
Query: 2298 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2357
ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN
Sbjct: 2341 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2400
Query: 2358 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2417
NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ
Sbjct: 2401 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2460
Query: 2418 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2477
NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA
Sbjct: 2461 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2520
Query: 2478 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2537
SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH
Sbjct: 2521 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2580
Query: 2538 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2597
VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN
Sbjct: 2581 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2640
Query: 2598 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2657
TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD
Sbjct: 2641 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2700
Query: 2658 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2717
VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI
Sbjct: 2701 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2760
Query: 2718 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2777
GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI
Sbjct: 2761 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2820
Query: 2778 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2837
STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL
Sbjct: 2821 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2880
Query: 2838 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2897
ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG
Sbjct: 2881 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2940
Query: 2898 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 2957
TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV
Sbjct: 2941 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 3000
Query: 2958 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3017
LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR
Sbjct: 3001 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3060
Query: 3018 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3077
VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE
Sbjct: 3061 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3120
Query: 3078 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3137
VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK
Sbjct: 3121 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3180
Query: 3138 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3197
RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF
Sbjct: 3181 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3240
Query: 3198 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3257
IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI
Sbjct: 3241 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3300
Query: 3258 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3317
QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS
Sbjct: 3301 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3360
Query: 3318 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3377
VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL
Sbjct: 3361 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3420
Query: 3378 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3437
DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR
Sbjct: 3421 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3480
Query: 3438 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3497
ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV
Sbjct: 3481 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3540
Query: 3498 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3557
EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI
Sbjct: 3541 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3600
Query: 3558 HEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVE 3617
HEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVE
Sbjct: 3601 HEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVE 3660
Query: 3618 ILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAE 3677
ILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAE
Sbjct: 3661 ILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAE 3720
Query: 3678 RACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS 3710
RACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS
Sbjct: 3721 RACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS 3753
>gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Homo
sapiens]
Length = 3585
Score = 7016 bits (18204), Expect = 0.0
Identities = 3578/3582 (99%), Positives = 3580/3582 (99%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180
ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG
Sbjct: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180
Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240
ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL
Sbjct: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240
Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300
TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID
Sbjct: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300
Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360
LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ
Sbjct: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360
Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420
LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS
Sbjct: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420
Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL 480
ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL
Sbjct: 421 ADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTL 480
Query: 481 PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY 540
PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY
Sbjct: 481 PKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY 540
Query: 541 ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA 600
ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA
Sbjct: 541 ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNA 600
Query: 601 VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ 660
VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ
Sbjct: 601 VVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQ 660
Query: 661 TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA 720
TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA
Sbjct: 661 TGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA 720
Query: 721 EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK 780
EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK
Sbjct: 721 EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMK 780
Query: 781 DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED 840
DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED
Sbjct: 781 DVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAED 840
Query: 841 GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG 900
GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG
Sbjct: 841 GEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG 900
Query: 901 TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP 960
TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP
Sbjct: 901 TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGP 960
Query: 961 SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ 1020
SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ
Sbjct: 961 SFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQ 1020
Query: 1021 QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ 1080
QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ
Sbjct: 1021 QKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ 1080
Query: 1081 SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL 1140
SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL
Sbjct: 1081 SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSL 1140
Query: 1141 NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI 1200
NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI
Sbjct: 1141 NVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI 1200
Query: 1201 DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR 1260
DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR
Sbjct: 1201 DLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR 1260
Query: 1261 TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL 1320
TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL
Sbjct: 1261 TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL 1320
Query: 1321 FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII 1380
FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII
Sbjct: 1321 FRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDII 1380
Query: 1381 NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD 1440
NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD
Sbjct: 1381 NMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD 1440
Query: 1441 FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH 1500
FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH
Sbjct: 1441 FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLH 1500
Query: 1501 LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA 1560
LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA
Sbjct: 1501 LEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITA 1560
Query: 1561 ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS 1620
ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS
Sbjct: 1561 ELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS 1620
Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680
ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ
Sbjct: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680
Query: 1681 TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL 1740
TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL
Sbjct: 1681 TAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGL 1740
Query: 1741 IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ 1800
IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ
Sbjct: 1741 IRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ 1800
Query: 1801 RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV 1860
RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV
Sbjct: 1801 RNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETV 1860
Query: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH 1920
RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH
Sbjct: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFH 1920
Query: 1921 NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN 1980
NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN
Sbjct: 1921 NDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDN 1980
Query: 1981 NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP 2040
NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP
Sbjct: 1981 NSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILP 2040
Query: 2041 RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL 2100
RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL
Sbjct: 2041 RQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKL 2100
Query: 2101 EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK 2160
EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK
Sbjct: 2101 EQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIK 2160
Query: 2161 ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES 2220
ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES
Sbjct: 2161 ISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITES 2220
Query: 2221 FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT 2280
FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT
Sbjct: 2221 FKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVT 2280
Query: 2281 LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS 2340
LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS
Sbjct: 2281 LQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISS 2340
Query: 2341 GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR 2400
GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR
Sbjct: 2341 GNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLR 2400
Query: 2401 VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI 2460
VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI
Sbjct: 2401 VMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANI 2460
Query: 2461 PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN 2520
PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN
Sbjct: 2461 PVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKN 2520
Query: 2521 VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC 2580
VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC
Sbjct: 2521 VKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRC 2580
Query: 2581 MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL 2640
MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL
Sbjct: 2581 MLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYL 2640
Query: 2641 LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS 2700
LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS
Sbjct: 2641 LEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSS 2700
Query: 2701 DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF 2760
DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF
Sbjct: 2701 DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILF 2760
Query: 2761 SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS 2820
SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS
Sbjct: 2761 SFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLS 2820
Query: 2821 RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV 2880
RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV
Sbjct: 2821 RIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVV 2880
Query: 2881 GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT 2940
GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT
Sbjct: 2881 GCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHT 2940
Query: 2941 PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY 3000
PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY
Sbjct: 2941 PWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPY 3000
Query: 3001 DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES 3060
DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES
Sbjct: 3001 DANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNES 3060
Query: 3061 KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN 3120
KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN
Sbjct: 3061 KQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVN 3120
Query: 3121 FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH 3180
FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH
Sbjct: 3121 FDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFH 3180
Query: 3181 PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL 3240
PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL
Sbjct: 3181 PVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIAL 3240
Query: 3241 FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS 3300
FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS
Sbjct: 3241 FTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGS 3300
Query: 3301 GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR 3360
GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR
Sbjct: 3301 GGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVR 3360
Query: 3361 HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV 3420
HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV
Sbjct: 3361 HYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGV 3420
Query: 3421 RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG 3480
RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG
Sbjct: 3421 RSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKG 3480
Query: 3481 FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR 3540
FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR
Sbjct: 3481 FLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR 3540
Query: 3541 AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLENHIK 3582
AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLE ++
Sbjct: 3541 AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLEQELE 3582
>gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Homo
sapiens]
Length = 3628
Score = 6995 bits (18150), Expect = 0.0
Identities = 3578/3625 (98%), Positives = 3580/3625 (98%), Gaps = 43/3625 (1%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG
Sbjct: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE
Sbjct: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
Query: 121 ALQKAAEK-------------------------------------------DKPKEAKKD 137
ALQKAAEK DKPKEAKKD
Sbjct: 121 ALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD 180
Query: 138 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 197
TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN
Sbjct: 181 TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
Query: 198 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 257
EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS
Sbjct: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
Query: 258 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 317
ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY
Sbjct: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
Query: 318 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 377
KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK
Sbjct: 361 KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSK 420
Query: 378 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 437
VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK
Sbjct: 421 VSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGK 480
Query: 438 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 497
KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS
Sbjct: 481 KESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS 540
Query: 498 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 557
VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI
Sbjct: 541 VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASI 600
Query: 558 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 617
GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT
Sbjct: 601 GDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQIT 660
Query: 618 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 677
SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT
Sbjct: 661 SATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT 720
Query: 678 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 737
FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI
Sbjct: 721 FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHI 780
Query: 738 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 797
LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA
Sbjct: 781 LQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSA 840
Query: 798 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 857
QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA
Sbjct: 841 QSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA 900
Query: 858 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 917
AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK
Sbjct: 901 AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLK 960
Query: 918 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 977
KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF
Sbjct: 961 KISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAF 1020
Query: 978 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1037
SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD
Sbjct: 1021 SSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD 1080
Query: 1038 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1097
IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK
Sbjct: 1081 IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPK 1140
Query: 1098 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1157
TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL
Sbjct: 1141 TVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSL 1200
Query: 1158 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1217
LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN
Sbjct: 1201 LNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN 1260
Query: 1218 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1277
AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP
Sbjct: 1261 AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHP 1320
Query: 1278 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1337
INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK
Sbjct: 1321 INLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK 1380
Query: 1338 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1397
VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK
Sbjct: 1381 VKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK 1440
Query: 1398 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1457
KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV
Sbjct: 1441 KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNV 1500
Query: 1458 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1517
TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF
Sbjct: 1501 TDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPF 1560
Query: 1518 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1577
SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA
Sbjct: 1561 SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA 1620
Query: 1578 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1637
DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA
Sbjct: 1621 DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDA 1680
Query: 1638 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1697
TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA
Sbjct: 1681 TEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERA 1740
Query: 1698 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1757
ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL
Sbjct: 1741 ASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL 1800
Query: 1758 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1817
PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK
Sbjct: 1801 PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIK 1860
Query: 1818 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1877
GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ
Sbjct: 1861 GKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQ 1920
Query: 1878 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1937
EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS
Sbjct: 1921 EDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASS 1980
Query: 1938 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 1997
GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ
Sbjct: 1981 GKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQ 2040
Query: 1998 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2057
IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR
Sbjct: 2041 IDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVR 2100
Query: 2058 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2117
PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP
Sbjct: 2101 PNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACP 2160
Query: 2118 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2177
FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS
Sbjct: 2161 FLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALS 2220
Query: 2178 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2237
PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV
Sbjct: 2221 PKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVV 2280
Query: 2238 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2297
ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI
Sbjct: 2281 ESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLI 2340
Query: 2298 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2357
ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN
Sbjct: 2341 ERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFN 2400
Query: 2358 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2417
NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ
Sbjct: 2401 NLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQ 2460
Query: 2418 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2477
NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA
Sbjct: 2461 NLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNA 2520
Query: 2478 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2537
SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH
Sbjct: 2521 SHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFH 2580
Query: 2538 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2597
VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN
Sbjct: 2581 VPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVN 2640
Query: 2598 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2657
TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD
Sbjct: 2641 TVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTAD 2700
Query: 2658 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2717
VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI
Sbjct: 2701 VLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRI 2760
Query: 2718 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2777
GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI
Sbjct: 2761 GSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKI 2820
Query: 2778 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2837
STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL
Sbjct: 2821 STSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSL 2880
Query: 2838 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2897
ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG
Sbjct: 2881 ELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNG 2940
Query: 2898 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 2957
TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV
Sbjct: 2941 TLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMV 3000
Query: 2958 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3017
LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR
Sbjct: 3001 LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQR 3060
Query: 3018 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3077
VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE
Sbjct: 3061 VLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWE 3120
Query: 3078 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3137
VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK
Sbjct: 3121 VKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIK 3180
Query: 3138 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3197
RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF
Sbjct: 3181 RDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPF 3240
Query: 3198 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3257
IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI
Sbjct: 3241 IDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLI 3300
Query: 3258 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3317
QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS
Sbjct: 3301 QQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHS 3360
Query: 3318 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3377
VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL
Sbjct: 3361 VNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGL 3420
Query: 3378 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3437
DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR
Sbjct: 3421 DVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSR 3480
Query: 3438 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3497
ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV
Sbjct: 3481 ITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPV 3540
Query: 3498 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3557
EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI
Sbjct: 3541 EGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLI 3600
Query: 3558 HEDGIIRPYDRQESEGSDLLENHIK 3582
HEDGIIRPYDRQESEGSDLLE ++
Sbjct: 3601 HEDGIIRPYDRQESEGSDLLEQELE 3625
>gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]
Length = 3174
Score = 1700 bits (4402), Expect = 0.0
Identities = 1005/2610 (38%), Positives = 1544/2610 (59%), Gaps = 150/2610 (5%)
Query: 1145 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1196
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
Query: 1197 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1248
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
Query: 1249 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1291
D+QLT + L +R + + I + NLE F+ R
Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
Query: 1292 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1338
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Query: 1339 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1382
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
Query: 1383 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1442
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
Query: 1443 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1502
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
Query: 1503 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1561
ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE
Sbjct: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057
Query: 1562 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1621
L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117
Query: 1622 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1681
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ
Sbjct: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177
Query: 1682 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1741
AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237
Query: 1742 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1801
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R
Sbjct: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297
Query: 1802 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1860
NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357
Query: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1915
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416
Query: 1916 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 1975
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476
Query: 1976 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2035
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E
Sbjct: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532
Query: 2036 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2095
T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587
Query: 2096 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2155
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647
Query: 2156 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2215
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T
Sbjct: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706
Query: 2216 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2273
E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762
Query: 2274 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2325
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + +
Sbjct: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822
Query: 2326 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2384
+ +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF +
Sbjct: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881
Query: 2385 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2444
N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S
Sbjct: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938
Query: 2445 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2504
F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI
Sbjct: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998
Query: 2505 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2564
+NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E
Sbjct: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051
Query: 2565 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2623
+ EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL
Sbjct: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107
Query: 2624 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2682
+P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167
Query: 2683 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2741
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY
Sbjct: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
Query: 2742 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2801
+++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287
Query: 2802 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2861
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW +
Sbjct: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341
Query: 2862 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2921
+C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV
Sbjct: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401
Query: 2922 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 2980
ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461
Query: 2981 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3039
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E
Sbjct: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519
Query: 3040 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3097
A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579
Query: 3098 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3153
++++ S + I+LD N V M++ P ++R++L +++E+ S+H
Sbjct: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639
Query: 3154 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3213
Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++
Sbjct: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699
Query: 3214 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3273
+ KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757
Query: 3274 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3331
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD
Sbjct: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817
Query: 3332 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3391
V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S
Sbjct: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877
Query: 3392 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3451
EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 3452 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3511
D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 3512 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3571
+GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056
Query: 3572 EGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVEILGLMCVDWQCPFE 3631
G+ +L+ ++ Y+Y + +K +LM+T R VL + + L C +WQ F+
Sbjct: 3057 TGNQMLQ-VMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTC-EWQYSFD 3114
Query: 3632 DFVFPP-SVSENVLKISVKE--QGLFHKKD 3658
+F P V L+I KE + +FH ++
Sbjct: 3115 EFTKEPFIVHGRRLRIEAKERVKSVFHARE 3144
Score = 1149 bits (2971), Expect = 0.0
Identities = 616/1353 (45%), Positives = 889/1353 (65%), Gaps = 39/1353 (2%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180
A QK ++++ K+DTF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L
Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240
LS+ T +++W PC+ +E +K++ KLIRLD+L AYWNV M Y + LD LKN I+
Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300
+P Y ++F+PISA+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++
Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360
LLESVD M +N PYRK+KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ
Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420
+K YK YK KLT K E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+
Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLT 479
E GWFS LW E +++ + PET+++++TPEEK L+ AIGYSE+ + T
Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
Query: 480 LPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHW 539
L K + A + L S S+ +REN PE++ I I T + QRPGAQA+K E K++ +
Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
Query: 540 YITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVN 599
+ITGL P L++S+ D SL +I FE NP D Q I++++P+E+IYDA+TVN
Sbjct: 541 HITGLPDNSEKPRLLSSL-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVN 599
Query: 600 AVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVP 659
++VEFF+ K + L Q+T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VP
Sbjct: 600 SIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVP 659
Query: 660 QTGFHHEKSDLLILDFGTFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLL 716
Q G S+LL+LD G ++ SK + K ++L+EIMD+AYD FD+++ +VQLL
Sbjct: 660 QDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLL 719
Query: 717 FARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISD 776
++R + W++ R ST HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD
Sbjct: 720 YSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISD 779
Query: 777 QKMKDVLYLMNSIPLPQKSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV-------- 827
+K++ ++ L+ SIP P+ P +VS+ + T LGTS + +
Sbjct: 780 KKLQGIMELIESIPKPE------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPS 833
Query: 828 --ESESDDEYFDAEDGE-------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVI 878
E +S++E+FDA P KS++ +L+K + + + ++FE+ +V+
Sbjct: 834 VSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVL 891
Query: 879 LEFTKQQKE-EDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLI 937
+EF + E +++ V LG E +RT+DL ++LK+ L E +KP++L+
Sbjct: 892 IEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLV 951
Query: 938 SSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLT 997
++ D DLL +EY+KA+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL
Sbjct: 952 TTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLH 1011
Query: 998 TIIP-SDDQSISVAKEVQISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVC 1055
I+P S+++S V+ +TE + K + K A+ S + DII ++ A+L+ + +
Sbjct: 1012 NILPQSEEKSAPVS-----TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQ 1066
Query: 1056 NEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFN 1115
++K NI+EIKI+GLDS + ++ + + A+L NIIV D D ++KKAV I G EVF F
Sbjct: 1067 DQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFK 1126
Query: 1116 LDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAAT 1175
+ Y DAT G YTDM+ VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT
Sbjct: 1127 MVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEAT 1186
Query: 1176 AQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLV 1235
QAA AAT VK+LAQRS R++++I++KAPV+VIPQS +S N V D GLI + N F ++
Sbjct: 1187 VQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMI 1246
Query: 1236 SDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHK 1295
++ PPVID + ++L+++ LYR+ Y + LL P+NLE +V RNL WY +
Sbjct: 1247 TESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQE 1306
Query: 1296 VPVVEIKGHLDSMNVSLNQEDLNLLFRILTENL 1328
VP + L M L+QED+ +F+ L N+
Sbjct: 1307 VPCFNVNAQLKPMEFILSQEDITTIFKTLHGNI 1339
Score = 54.7 bits (130), Expect = 2e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 1517 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1564
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
Query: 1565 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1620
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
Query: 1681 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1729
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
Query: 1730 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1778
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
Query: 1779 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1835
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
Query: 1836 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1869
M+++ E+ +P P V V+ ++ S+
Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
>gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]
Length = 3095
Score = 1679 bits (4347), Expect = 0.0
Identities = 982/2527 (38%), Positives = 1504/2527 (59%), Gaps = 145/2527 (5%)
Query: 1145 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1196
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
Query: 1197 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1248
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
Query: 1249 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1291
D+QLT + L +R + + I + NLE F+ R
Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
Query: 1292 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1338
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Query: 1339 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1382
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
Query: 1383 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1442
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
Query: 1443 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1502
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
Query: 1503 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1561
ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE
Sbjct: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057
Query: 1562 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1621
L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117
Query: 1622 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1681
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ
Sbjct: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177
Query: 1682 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1741
AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237
Query: 1742 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1801
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R
Sbjct: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297
Query: 1802 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1860
NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357
Query: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1915
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416
Query: 1916 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 1975
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476
Query: 1976 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2035
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E
Sbjct: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532
Query: 2036 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2095
T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587
Query: 2096 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2155
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647
Query: 2156 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2215
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T
Sbjct: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706
Query: 2216 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2273
E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762
Query: 2274 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2325
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + +
Sbjct: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822
Query: 2326 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2384
+ +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF +
Sbjct: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881
Query: 2385 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2444
N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S
Sbjct: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938
Query: 2445 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2504
F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI
Sbjct: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998
Query: 2505 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2564
+NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E
Sbjct: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051
Query: 2565 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2623
+ EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL
Sbjct: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107
Query: 2624 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2682
+P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167
Query: 2683 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2741
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY
Sbjct: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
Query: 2742 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2801
+++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287
Query: 2802 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2861
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW +
Sbjct: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341
Query: 2862 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2921
+C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV
Sbjct: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401
Query: 2922 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 2980
ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461
Query: 2981 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3039
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E
Sbjct: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519
Query: 3040 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3097
A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579
Query: 3098 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3153
++++ S + I+LD N V M++ P ++R++L +++E+ S+H
Sbjct: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639
Query: 3154 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3213
Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++
Sbjct: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699
Query: 3214 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3273
+ KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757
Query: 3274 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3331
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD
Sbjct: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817
Query: 3332 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3391
V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S
Sbjct: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877
Query: 3392 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3451
EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 3452 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3511
D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 3512 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3571
+GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056
Query: 3572 EGSDLLE 3578
G+ +L+
Sbjct: 3057 TGNQMLQ 3063
Score = 1149 bits (2971), Expect = 0.0
Identities = 616/1353 (45%), Positives = 889/1353 (65%), Gaps = 39/1353 (2%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180
A QK ++++ K+DTF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L
Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240
LS+ T +++W PC+ +E +K++ KLIRLD+L AYWNV M Y + LD LKN I+
Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300
+P Y ++F+PISA+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++
Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360
LLESVD M +N PYRK+KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ
Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420
+K YK YK KLT K E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+
Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLT 479
E GWFS LW E +++ + PET+++++TPEEK L+ AIGYSE+ + T
Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
Query: 480 LPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHW 539
L K + A + L S S+ +REN PE++ I I T + QRPGAQA+K E K++ +
Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
Query: 540 YITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVN 599
+ITGL P L++S+ D SL +I FE NP D Q I++++P+E+IYDA+TVN
Sbjct: 541 HITGLPDNSEKPRLLSSL-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVN 599
Query: 600 AVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVP 659
++VEFF+ K + L Q+T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VP
Sbjct: 600 SIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVP 659
Query: 660 QTGFHHEKSDLLILDFGTFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLL 716
Q G S+LL+LD G ++ SK + K ++L+EIMD+AYD FD+++ +VQLL
Sbjct: 660 QDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLL 719
Query: 717 FARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISD 776
++R + W++ R ST HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD
Sbjct: 720 YSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISD 779
Query: 777 QKMKDVLYLMNSIPLPQKSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV-------- 827
+K++ ++ L+ SIP P+ P +VS+ + T LGTS + +
Sbjct: 780 KKLQGIMELIESIPKPE------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPS 833
Query: 828 --ESESDDEYFDAEDGE-------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVI 878
E +S++E+FDA P KS++ +L+K + + + ++FE+ +V+
Sbjct: 834 VSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVL 891
Query: 879 LEFTKQQKE-EDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLI 937
+EF + E +++ V LG E +RT+DL ++LK+ L E +KP++L+
Sbjct: 892 IEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLV 951
Query: 938 SSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLT 997
++ D DLL +EY+KA+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL
Sbjct: 952 TTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLH 1011
Query: 998 TIIP-SDDQSISVAKEVQISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVC 1055
I+P S+++S V+ +TE + K + K A+ S + DII ++ A+L+ + +
Sbjct: 1012 NILPQSEEKSAPVS-----TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQ 1066
Query: 1056 NEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFN 1115
++K NI+EIKI+GLDS + ++ + + A+L NIIV D D ++KKAV I G EVF F
Sbjct: 1067 DQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFK 1126
Query: 1116 LDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAAT 1175
+ Y DAT G YTDM+ VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT
Sbjct: 1127 MVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEAT 1186
Query: 1176 AQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLV 1235
QAA AAT VK+LAQRS R++++I++KAPV+VIPQS +S N V D GLI + N F ++
Sbjct: 1187 VQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMI 1246
Query: 1236 SDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHK 1295
++ PPVID + ++L+++ LYR+ Y + LL P+NLE +V RNL WY +
Sbjct: 1247 TESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQE 1306
Query: 1296 VPVVEIKGHLDSMNVSLNQEDLNLLFRILTENL 1328
VP + L M L+QED+ +F+ L N+
Sbjct: 1307 VPCFNVNAQLKPMEFILSQEDITTIFKTLHGNI 1339
Score = 54.7 bits (130), Expect = 2e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 1517 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1564
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
Query: 1565 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1620
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
Query: 1681 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1729
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
Query: 1730 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1778
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
Query: 1779 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1835
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
Query: 1836 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1869
M+++ E+ +P P V V+ ++ S+
Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
>gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]
Length = 3069
Score = 1679 bits (4347), Expect = 0.0
Identities = 982/2527 (38%), Positives = 1504/2527 (59%), Gaps = 145/2527 (5%)
Query: 1145 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1196
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
Query: 1197 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1248
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
Query: 1249 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1291
D+QLT + L +R + + I + NLE F+ R
Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
Query: 1292 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1338
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Query: 1339 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1382
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
Query: 1383 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1442
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
Query: 1443 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1502
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
Query: 1503 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNIS-QKDVFDLKITAE 1561
ALL+ +++L + P SE EK + + E + +K ++ +S +D+ L+I AE
Sbjct: 1002 ALLNTINYLHNILPQSE----EKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAE 1057
Query: 1562 LNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSI 1621
L+ +F+ DQKCNI++IKI G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1058 LSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYI 1117
Query: 1622 LGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQT 1681
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ
Sbjct: 1118 TGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQA 1177
Query: 1682 AKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLI 1741
AK+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1178 AKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLI 1237
Query: 1742 RVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQR 1801
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++R
Sbjct: 1238 TMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVER 1297
Query: 1802 NLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETV 1860
NL WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1298 NLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYS 1357
Query: 1861 RVRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQES 1915
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1358 ATSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQAS 1416
Query: 1916 GVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRK 1975
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1417 FTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLT 1476
Query: 1976 NDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKE 2035
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A E
Sbjct: 1477 VGFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVE 1532
Query: 2036 TQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSL 2095
T + QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 1533 TSV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICY 1587
Query: 2096 STSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVK 2155
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 1588 KGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK 1647
Query: 2156 EFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTAT 2215
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL T
Sbjct: 1648 SLTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNET 1706
Query: 2216 EITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLM 2273
E + + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 1707 EKIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLI 1762
Query: 2274 AAVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPG 2325
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + +
Sbjct: 1763 NLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEE 1822
Query: 2326 DDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVK 2384
+ +PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF +
Sbjct: 1823 NYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMIL 1881
Query: 2385 NAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSF 2444
N++G+ I V P+ + V+ P + + G++L ++Y + N ++ S
Sbjct: 1882 NSLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKL 1938
Query: 2445 FTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQI 2504
F + + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI
Sbjct: 1939 FFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQI 1998
Query: 2505 KNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTT 2564
+NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E
Sbjct: 1999 RNHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGID 2051
Query: 2565 YISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHL 2623
+ EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL
Sbjct: 2052 F----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHL 2107
Query: 2624 YPSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNG 2682
+P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2108 WPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKS 2167
Query: 2683 HFRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQY 2741
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY
Sbjct: 2168 EYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
Query: 2742 RSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPA 2801
+++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2228 KADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKG 2287
Query: 2802 NNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASS 2861
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW +
Sbjct: 2288 LKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLE 2341
Query: 2862 ECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTV 2921
+C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTV
Sbjct: 2342 QCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTV 2401
Query: 2922 ITFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWT 2980
ITF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2402 ITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWR 2461
Query: 2981 YAANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQ 3039
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E
Sbjct: 2462 CRKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL 2519
Query: 3040 ADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQ 3097
A+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 2520 AEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLER 2579
Query: 3098 SYQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSH 3153
++++ S + I+LD N V M++ P ++R++L +++E+ S+H
Sbjct: 2580 EFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAH 2639
Query: 3154 QRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVL 3213
Q S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++
Sbjct: 2640 QSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQIS 2699
Query: 3214 QFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSM 3273
+ KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 2700 RIKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASL 2757
Query: 3274 TDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTD 3331
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTD
Sbjct: 2758 VDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTD 2817
Query: 3332 VDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLS 3391
V D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR S
Sbjct: 2818 VQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFS 2877
Query: 3392 EGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITM 3451
EGVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TM
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 3452 DKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKG 3511
D++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 3512 IGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQES 3571
+GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDG 3056
Query: 3572 EGSDLLE 3578
G+ +L+
Sbjct: 3057 TGNQMLQ 3063
Score = 1149 bits (2971), Expect = 0.0
Identities = 616/1353 (45%), Positives = 889/1353 (65%), Gaps = 39/1353 (2%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180
A QK ++++ K+DTF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L
Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240
LS+ T +++W PC+ +E +K++ KLIRLD+L AYWNV M Y + LD LKN I+
Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300
+P Y ++F+PISA+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++
Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360
LLESVD M +N PYRK+KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ
Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420
+K YK YK KLT K E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+
Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLT 479
E GWFS LW E +++ + PET+++++TPEEK L+ AIGYSE+ + T
Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
Query: 480 LPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHW 539
L K + A + L S S+ +REN PE++ I I T + QRPGAQA+K E K++ +
Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
Query: 540 YITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVN 599
+ITGL P L++S+ D SL +I FE NP D Q I++++P+E+IYDA+TVN
Sbjct: 541 HITGLPDNSEKPRLLSSL-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVN 599
Query: 600 AVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVP 659
++VEFF+ K + L Q+T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VP
Sbjct: 600 SIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVP 659
Query: 660 QTGFHHEKSDLLILDFGTFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLL 716
Q G S+LL+LD G ++ SK + K ++L+EIMD+AYD FD+++ +VQLL
Sbjct: 660 QDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLL 719
Query: 717 FARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISD 776
++R + W++ R ST HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD
Sbjct: 720 YSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISD 779
Query: 777 QKMKDVLYLMNSIPLPQKSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV-------- 827
+K++ ++ L+ SIP P+ P +VS+ + T LGTS + +
Sbjct: 780 KKLQGIMELIESIPKPE------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPS 833
Query: 828 --ESESDDEYFDAEDGE-------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVI 878
E +S++E+FDA P KS++ +L+K + + + ++FE+ +V+
Sbjct: 834 VSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVL 891
Query: 879 LEFTKQQKE-EDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLI 937
+EF + E +++ V LG E +RT+DL ++LK+ L E +KP++L+
Sbjct: 892 IEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLV 951
Query: 938 SSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLT 997
++ D DLL +EY+KA+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL
Sbjct: 952 TTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLH 1011
Query: 998 TIIP-SDDQSISVAKEVQISTEKQQKNSTLPK-AIVSSRDSDIIDFRLFAKLNAFCVIVC 1055
I+P S+++S V+ +TE + K + K A+ S + DII ++ A+L+ + +
Sbjct: 1012 NILPQSEEKSAPVS-----TTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQ 1066
Query: 1056 NEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFN 1115
++K NI+EIKI+GLDS + ++ + + A+L NIIV D D ++KKAV I G EVF F
Sbjct: 1067 DQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFK 1126
Query: 1116 LDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAAT 1175
+ Y DAT G YTDM+ VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT
Sbjct: 1127 MVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEAT 1186
Query: 1176 AQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLV 1235
QAA AAT VK+LAQRS R++++I++KAPV+VIPQS +S N V D GLI + N F ++
Sbjct: 1187 VQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMI 1246
Query: 1236 SDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHK 1295
++ PPVID + ++L+++ LYR+ Y + LL P+NLE +V RNL WY +
Sbjct: 1247 TESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQE 1306
Query: 1296 VPVVEIKGHLDSMNVSLNQEDLNLLFRILTENL 1328
VP + L M L+QED+ +F+ L N+
Sbjct: 1307 VPCFNVNAQLKPMEFILSQEDITTIFKTLHGNI 1339
Score = 54.7 bits (130), Expect = 2e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 1517 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1564
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
Query: 1565 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1620
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
Query: 1681 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1729
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
Query: 1730 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1778
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
Query: 1779 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1835
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
Query: 1836 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1869
M+++ E+ +P P V V+ ++ S+
Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
>gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]
Length = 3135
Score = 1649 bits (4269), Expect = 0.0
Identities = 991/2609 (37%), Positives = 1517/2609 (58%), Gaps = 187/2609 (7%)
Query: 1145 IQIVYLHKFLMSLLNFLNNFQTAKE----SLSAATAQAAE----RAATSVKDLAQRSFRV 1196
++I+Y + + S++ F F+ KE L+AAT E + AT + + + +
Sbjct: 589 LEIIYDARTVNSIVEF---FRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVL 645
Query: 1197 SINIDLKAPVIVIPQSSI---STNAVVVDLGLIRV----HNQFSLVSDEDYLNPPVIDR- 1248
+ I+LKA I++PQ I ++N +++DLG ++V ++ V + ++DR
Sbjct: 646 DLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRA 705
Query: 1249 ---MDVQLTKLTL--------YRTVIQPGIYHPDIQLLHPINLE------FLVNRNLAAS 1291
D+QLT + L +R + + I + NLE F+ R
Sbjct: 706 YDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFK 765
Query: 1292 WYHKVPVVEIK-------GHLDSMNVSLNQEDLNLL------FRILTENLCEGTEDLDKV 1338
Y K+P++ ++ G ++ + E + + F+I T ++ K+
Sbjct: 766 IYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKI 825
Query: 1339 KPRVQETGEIKEPLEISISQDVHDSKNT-------LTTGVEEIR---------SVDIINM 1382
P + E+ E ++ D+ + TGV+ IR SV++
Sbjct: 826 IPLL----ELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTF 881
Query: 1383 LLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFT 1442
+ FE+ +V++ + E+ VL LG E +++TYD+ A A+LK+ ++C ++
Sbjct: 882 KIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYL 941
Query: 1443 DSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLE 1502
D +P++++ + + T E LL + KA+ + P+ K+ +++ Q +KV+F+SLD+ LH E
Sbjct: 942 DENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTE 1001
Query: 1503 ALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAEL 1562
ALL+ +++L + P SE S A S +D D+
Sbjct: 1002 ALLNTINYLHNILPQSEEKS--------------------APVSTTETEDKGDV------ 1035
Query: 1563 NAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSIL 1622
IK G+D+ + ++P +T++ A+L++IIV++ D+ +I+KKAV I
Sbjct: 1036 ----------------IKKLGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYIT 1079
Query: 1623 GDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTA 1682
G EVF F++ Y DAT G AY DM+ VD +++ VGCI++V+V KF S+L F++NFQ A
Sbjct: 1080 GKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAA 1139
Query: 1683 KEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIR 1742
K+AL+ ATVQAA AA+ +K+LAQ+S R+ +DIN+KAPV++IPQS VS N +AD GLI
Sbjct: 1140 KQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLIT 1199
Query: 1743 VENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRN 1802
+ N F ++ S PPVID + I+L++++L R+ Q +++L P+N+ + ++RN
Sbjct: 1200 MTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERN 1259
Query: 1803 LAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLG-EASSQPSPTQSVQETVR 1861
L WY ++P + +LKPM+ LS++D+T + K L N+ E SP + +
Sbjct: 1260 LCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSA 1319
Query: 1862 VRKVDVSSVPDHLKEQEDWTDSKLSMNQIV-----SLQFDFHFESLSIILYNNDINQESG 1916
V ++ H T + + ++ +L F + L+++LY+ Q S
Sbjct: 1320 TSGV-TTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASF 1378
Query: 1917 VAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKN 1976
+ S +L E +L + S+ KM+ DGS S LK C LDD R +++AT RMI
Sbjct: 1379 TDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTV 1438
Query: 1977 DQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKET 2036
D M+DI Y++ ++G DAV ++Y+CASVEFL TVA+ F++A A ET
Sbjct: 1439 GFDKKD-MMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTG---TAVET 1494
Query: 2037 QILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLS 2096
+ QT T K ++ +SV+ + +I +PE+VFVA +TK DAPAL + QC +
Sbjct: 1495 SV---QTWTAKEEVPTQESVK--WEINVIIKNPEIVFVADMTKNDAPALVITTQCEICYK 1549
Query: 2097 TSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKE 2156
+ M A+++DL+V ACPFL KR ITTVLQPC LF + + Q I++ VK
Sbjct: 1550 GNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVKS 1609
Query: 2157 FIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATE 2216
+K+SP+I+NT++TI +AL TKE ++T+ +LW K WFL TE
Sbjct: 1610 LTLKVSPVIINTMITITSALYT-TKETIPEETASSTAHLWEKKDTKTLKMWFLEESNETE 1668
Query: 2217 ITESFKGI--EHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMA 2274
+ + +I+ N ++SI + LE G+GHRTVP+LLA+S+FSG KNW+SL+
Sbjct: 1669 KIAPTTELVPKGEMIKMN----IDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLIN 1724
Query: 2275 AVADVTLQVHYYNEIHAVWEPLIE-----RVEGKRQWNLRLDVKKNP---VQDKSLLPGD 2326
+ L+VHYYNE+ VWEPL+E + E R WNL + +KK + + +
Sbjct: 1725 LHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEEN 1784
Query: 2327 DFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEG-TASTFDYSLKDRAPFTVKN 2385
+PE + I S + +NIT+SK L + NNL K F+E T S+ D+ +KD APF + N
Sbjct: 1785 YKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADF-VKDLAPFMILN 1843
Query: 2386 AVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFF 2445
++G+ I V P+ + V+ P + + G++L ++Y + N ++ S F
Sbjct: 1844 SLGLTISVSPSDSFSVLNIPMAKS-YVLKNGESLSMDYIRTKDNDHFNA--MTSLSSKLF 1900
Query: 2446 TLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIK 2505
+ + P ++ IP+ + GRRLY VR+ + S++ QID EG+K +T+RSP+QI+
Sbjct: 1901 FILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQIR 1960
Query: 2506 NHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTY 2565
NHFS+ +Y+ +G A PE EF++PL SYR +F++P +Q E +
Sbjct: 1961 NHFSVPLSVYEGDT------LLGTASPENEFNIPLGSYRSFIFLKPEDE-NYQMCEGIDF 2013
Query: 2566 ISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGED-WDVAYIIHLY 2624
EE+ ++ +C S S ++N V D L+ + + ED WD+ YI+HL+
Sbjct: 2014 ----EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHLW 2069
Query: 2625 PSLTLRNLLPYSLRYLLEGTAET-HELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGH 2683
P + LRNLLPY + Y +EG + L+EG +A + +++ + L L+ Y +W
Sbjct: 2070 PPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKSE 2129
Query: 2684 FRIRDTLPEFFPVCFSS-DSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYR 2742
+ I+ + V F+ E T +D++VH+ + V++ SPYW++NKT R+LQY+
Sbjct: 2130 YHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQYK 2189
Query: 2743 SEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPAN 2802
++ IH KHP +++ +LFSF+ + F NKVQL ++ S S+ FS+DTVGS+G VKC
Sbjct: 2190 ADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKGL 2249
Query: 2803 NMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSE 2862
M+Y VGV+I +SSFN++RIVT TPF I NKS + V E +D KW + +
Sbjct: 2250 KMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGND------KWLSLDLEQ 2303
Query: 2863 CLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVI 2922
C+PFWPE S KL ++V E K ++N+Q+N LL L++ GGI+ +VN AEHSTVI
Sbjct: 2304 CIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTVI 2363
Query: 2923 TFSDYHEGSAPALIMNHTPWDILTYKQSGSPE-EMVLLPRQARLFAWADPTGTRKLTWTY 2981
TF DYH+G+A L++NHT +++ Y QS E E L P +A + WADP G+R+L W
Sbjct: 2364 TFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWRC 2423
Query: 2982 AANVGEHDLLKDGCGQFPYDANIQ-IHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQA 3040
+ GE D P D + I+ VSF +G QR++LFT+D + ++E+ E A
Sbjct: 2424 RKSHGEVTQKDDM--MMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELA 2481
Query: 3041 DYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQK--WKPFSQKQIILLEQS 3098
+ EI ++L +G+SLVNN +KQEV+YIGITSS VVWE KPK+K WKP S K LE+
Sbjct: 2482 EQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLERE 2541
Query: 3099 YQKHQISR--DHGWIKLDNNFEVNFDKDPMEMRL--PIRSPIKRDFLSGIQIEFKQSSHQ 3154
++++ S + I+LD N V M++ P ++R++L +++E+ S+HQ
Sbjct: 2542 FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQ 2601
Query: 3155 RSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQ 3214
S R ++Y +Q+ NQ+ GA+FP VF+PV PPKS+ +DS PKPF DVS++ R +S++ +
Sbjct: 2602 SSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISR 2661
Query: 3215 FKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSMT 3274
KYF VLIQEM L++D GF+ A+ L T E +L +DI+A E S+
Sbjct: 2662 IKYFKVLIQEMDLRLDLGFIYALTDLMTEAE--VTENTEVELFHKDIEAFKEEYKTASLV 2719
Query: 3275 DMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQE--MFAVHSVNLLLKSIGATLTDV 3332
D S +S +E+FHISP+KLHLS+SL SG EE+ KQ + VHS+NLLLKSIGATLTDV
Sbjct: 2720 DQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDV 2779
Query: 3333 DDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSE 3392
D++FKLA++E+ YQF+ L V+RHYS+Q +KQMYVL+LGLDVLGNPFGLIR SE
Sbjct: 2780 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSE 2839
Query: 3393 GVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMD 3452
GVEA FYEP+QGA+QGPEEF EG+ +G+++L G VGG AG S+ITG++ KG+AA+TMD
Sbjct: 2840 GVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMD 2899
Query: 3453 KEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGI 3512
++YQQKRRE +++QP F + + RGGKG + G V G+TGI+TKP++GA+K GAAGFFKG+
Sbjct: 2900 EDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGV 2959
Query: 3513 GKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQESE 3572
GKGLVGAVARPTGGI+DMASSTFQGI+RA E T EV SLRPPR +EDG+IRPY ++
Sbjct: 2960 GKGLVGAVARPTGGIIDMASSTFQGIKRATE-TSEVESLRPPRFFNEDGVIRPYRLRDGT 3018
Query: 3573 GSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVEILGLMCVDWQCPFED 3632
G+ +L+ ++ Y+Y + +K +LM+T R VL + + L C +WQ F++
Sbjct: 3019 GNQMLQ-VMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTC-EWQYSFDE 3076
Query: 3633 FVFPP-SVSENVLKISVKE--QGLFHKKD 3658
F P V L+I KE + +FH ++
Sbjct: 3077 FTKEPFIVHGRRLRIEAKERVKSVFHARE 3105
Score = 1108 bits (2865), Expect = 0.0
Identities = 601/1351 (44%), Positives = 863/1351 (63%), Gaps = 74/1351 (5%)
Query: 1 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAG 60
MV ESVV D+LNRFLGDYV +L+ SQL LGIW G VAL NLQIKENALS+LDVPFKVK G
Sbjct: 1 MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEE 120
I L L IPWKNLY + V A LE +YLL+VP + IKYD +KEEK L + KQ+EL RIEE
Sbjct: 61 HIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEE 120
Query: 121 ALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG 180
A QK ++++ K+DTF EKL TQ+IKN+QVKI+ IHI+YEDD+T+ +PLSFG++L
Sbjct: 121 AKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ 180
Query: 181 ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEIL 240
LS+ T +++W PC+ +E +K++ KLIRLD+L AYWNV M Y + LD LKN I+
Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
Query: 241 TSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMID 300
+P Y ++F+PISA+AKL MN ++ + PK++ IE+ NIAIE KPQY S+++
Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
Query: 301 LLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ 360
LLESVD M +N PYRK+KP +PLH + R WW YAI VLEV++ MWSW +I+KHRQ
Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
Query: 361 LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKS 420
+K YK YK KLT K E+ +++LEKTLDVFNI +ARQ A+VEV ++G K+ K+
Sbjct: 361 KVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEG 420
Query: 421 ADTGEKRGGWFSGLWGKKESKKKDEE-SLIPETIDDLMTPEEKDKLFTAIGYSESTHNLT 479
E GWFS LW E +++ + PET+++++TPEEK L+ AIGYSE+ + T
Sbjct: 421 VKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPT 480
Query: 480 LPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHW 539
L K + A + L S S+ +REN PE++ I I T + QRPGAQA+K E K++ +
Sbjct: 481 LLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSF 540
Query: 540 YITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVN 599
+ITGL P L++S+ D SL +I FE NP D Q I++++P+E+IYDA+TVN
Sbjct: 541 HITGLPDNSEKPRLLSSL-DDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVN 599
Query: 600 AVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVP 659
++VEFF+ K + L Q+T+ATL KLEE + +TATGL +IIET+KVLDL+INLK SY++VP
Sbjct: 600 SIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVP 659
Query: 660 QTGFHHEKSDLLILDFGTFQLNSKDQGL---QKTTNSSLEEIMDKAYDKFDVEIKNVQLL 716
Q G S+LL+LD G ++ SK + K ++L+EIMD+AYD FD+++ +VQLL
Sbjct: 660 QDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLL 719
Query: 717 FARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISD 776
++R + W++ R ST HIL PM ++EL+KAMV D+RM +FK+ G LPL+ +RISD
Sbjct: 720 YSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISD 779
Query: 777 QKMKDVLYLMNSIPLPQKSSAQSPERQVSS-IPIISGGTKGLLGTSLLLDTV-------- 827
+K++ ++ L+ SIP P+ P +VS+ + T LGTS + +
Sbjct: 780 KKLQGIMELIESIPKPE------PVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPS 833
Query: 828 --ESESDDEYFDAEDGE-------PQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVI 878
E +S++E+FDA P KS++ +L+K + + + ++FE+ +V+
Sbjct: 834 VSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQK--QDCSVNMTTFKIRFEVPKVL 891
Query: 879 LEFTKQQKE-EDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLI 937
+EF + E +++ V LG E +RT+DL ++LK+ L E +KP++L+
Sbjct: 892 IEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLV 951
Query: 938 SSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLT 997
++ D DLL +EY+KA+KN P ++ + Q +KV FSSL++ L T+AL+ +INYL
Sbjct: 952 TTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLH 1011
Query: 998 TIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNE 1057
I+P ++ K +ST + + +
Sbjct: 1012 NILPQSEE-----KSAPVSTTETE-----------------------------------D 1031
Query: 1058 KNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLD 1117
K ++ IK GLDS + ++ + + A+L NIIV D D ++KKAV I G EVF F +
Sbjct: 1032 KGDV--IKKLGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMV 1089
Query: 1118 LYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQ 1177
Y DAT G YTDM+ VD ++L VGCI++V++ KFL S+L F++NFQ AK++L+ AT Q
Sbjct: 1090 SYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQ 1149
Query: 1178 AAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSD 1237
AA AAT VK+LAQRS R++++I++KAPV+VIPQS +S N V D GLI + N F ++++
Sbjct: 1150 AAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITE 1209
Query: 1238 EDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVP 1297
PPVID + ++L+++ LYR+ Y + LL P+NLE +V RNL WY +VP
Sbjct: 1210 SQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVP 1269
Query: 1298 VVEIKGHLDSMNVSLNQEDLNLLFRILTENL 1328
+ L M L+QED+ +F+ L N+
Sbjct: 1270 CFNVNAQLKPMEFILSQEDITTIFKTLHGNI 1300
Score = 54.7 bits (130), Expect = 2e-06
Identities = 82/394 (20%), Positives = 175/394 (44%), Gaps = 57/394 (14%)
Query: 1517 FSEPSSSEKESELKP------LVGESRSIAVKAVSSNISQKD-----VFD-LKITAELNA 1564
+SE +++E++ +++P L E +++ +A+ + + D F+ LK L +
Sbjct: 437 WSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKS 496
Query: 1565 FNVFVCD--QKCNIADIKIHGMDASISVKPKQTDVF--ARLKDIIVMNVDLQSIHKKAVS 1620
++ + + QK + DI I I +P + ++ + + S + +S
Sbjct: 497 MSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLS 556
Query: 1621 ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQ 1680
L D + FQ+T + + V + + ++I+Y + S++ F F+
Sbjct: 557 SLDDAMSLFQITFEINPLD-------ETVSQRCIIEAEPLEIIYDARTVNSIVEF---FR 606
Query: 1681 TAKEA----LSTATVQAAE----RAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSV--- 1729
KE L+ AT+ E + A+ + + + L + INLKA II+PQ +
Sbjct: 607 PPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP 666
Query: 1730 SPNAVIADLGLIRVENK----FSLVPMEHYSLPPVIDK----MNIELTQLKLSRTIL--- 1778
+ N ++ DLG ++V +K V +L ++D+ +I+LT ++L + +
Sbjct: 667 TSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDN 726
Query: 1779 ---QASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVL 1835
L + IL P++ L + + + V++P +I GKL + + +S+ L +
Sbjct: 727 WREARKLSVSTQHILVPMHFNLELSKAM-VFMDVRMPKFKIYGKLPLISLRISDKKLQGI 785
Query: 1836 MKILLENLGEASSQPSPTQSVQETVRVRKVDVSS 1869
M+++ E+ +P P V V+ ++ S+
Sbjct: 786 MELI-----ESIPKPEPVTEVSAPVKSFQIQTST 814
Score = 33.5 bits (75), Expect = 4.0
Identities = 61/330 (18%), Positives = 128/330 (38%), Gaps = 36/330 (10%)
Query: 495 STSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLV 554
S V+ E ++ +++K +GL +++ RP ++ AKL + + I V
Sbjct: 1021 SAPVSTTETEDKGDVIKK--LGLDSEMIMRPSET--EINAKLRNIIVLDSDITAIYKKAV 1076
Query: 555 ASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQP------VEVIYDAKTVNAVVEF---F 605
G S + + S +V Q +EV++ K + +++ F F
Sbjct: 1077 YITGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNF 1136
Query: 606 QSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHH 665
Q+ K E A M ATG+ + + + L IN+K +V+PQ+
Sbjct: 1137 QAAKQALAEATVQAAGM--------AATGVKELAQRSSRMALDINIKAPVVVIPQSPV-- 1186
Query: 666 EKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWK 725
++ + DFG + + + ++ +S I D +++ ++L +R
Sbjct: 1187 -SENVFVADFGLITMTNTFHMITESQSSPPPVI-----DLITIKLSEMRLYRSRF----- 1235
Query: 726 KCRFQHPSTMHILQPMDIHVELAKAMV-EKDIRMARFKVSGGLPLMHVRISDQKMKDVLY 784
+ + +L P+++ V + + + E + F V+ L M +S + + +
Sbjct: 1236 -INDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFK 1294
Query: 785 LMNSIPLPQKSSAQSPERQVSSIPIISGGT 814
++ +K + SP SG T
Sbjct: 1295 TLHGNIWYEKDGSASPAVTKDQYSATSGVT 1324
>gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens]
Length = 4363
Score = 234 bits (596), Expect = 2e-60
Identities = 313/1479 (21%), Positives = 604/1479 (40%), Gaps = 268/1479 (18%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61
+LE +VA +LN +LG YV NLN QL + + G V L+NL +K++AL EL++PF+VKAG
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEA 121
I K+TL+IP+ + + V ++ L+L+ P ++ KE+ ++ K+ L +EE
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 122 LQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGE 181
+ ++ + E+ + + T++++N+++KI D+H+++ED VT+P P +FG+ +
Sbjct: 121 WKN--DRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKN 178
Query: 182 LSLLTANEHWTPCILNEADKIIYKLIRLD--SLSAYWNVNCSMSYQRSREQILDQLKNEI 239
+S+ A +NE + + + +LD S YW+V+C++ + ++ + + +
Sbjct: 179 VSMQNA--------VNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSM 230
Query: 240 LTSGNIPPNYQYIFQPISASAKLYMNPYAESELK---TPKLDCNIEIQNIAIELTKPQYL 296
+ ++ Y+ +P+ ASA L N ++ L+ +P++DC+I+++ I ++L++ QY
Sbjct: 231 ESR-----SHHYVLEPVFASALLKRN-CSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYR 284
Query: 297 SMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIK 356
+++ L+ ++ R +R++KP + + N R WW +A+++ L IR + +W +
Sbjct: 285 QIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANL-YEIREQRKRCTWDFML 343
Query: 357 KHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILAR---------QQAQV 407
+ SY Y NKL +S + ++E+ +E+ + + R Q+
Sbjct: 344 HRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELA 403
Query: 408 EVIRSGQKLRKKSADTGEKRGG----------WFSGLWGKKESKK------------KDE 445
E +R Q + + GG WF G WG ++ + +
Sbjct: 404 ESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPG-WGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 446 ESLIPETI-------------DDLMTPEEKDKLFTAIGYSESTHNLTL-------PKQYV 485
E IPE I + T ++D +F + +TL P+
Sbjct: 463 EQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNE 522
Query: 486 AHIMTL-----KLVSTSVTIRENKNIPEILKIQIIGL--------GTQ----VSQRPGAQ 528
+ M L KL++ S+ R + +L +++ GL GT V P +
Sbjct: 523 SAFMQLEFSDVKLLAESLPRRNS----SLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKE 578
Query: 529 ALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQP 588
+V GL+ S D + ++ +E NP S ++ L V ++P
Sbjct: 579 VGRVSQSF------GLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRP 632
Query: 589 VEVIYDAKTVNAVVEFFQSNK------GLDLE---QITSATLMKLEEIKERTATGLTH-- 637
+ +IY+ + + V +FF K G E ++ A + ++K +T +
Sbjct: 633 LNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTL 692
Query: 638 -------IIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGTFQL-NSKDQGLQK 689
IE K +R+++ ++ P F + L+++D G L N++D +K
Sbjct: 693 DRLLVGDFIEESKRWTVRLDISAPQVIFPD-DFKFKNPVLVVVDLGRMLLTNTQDNSRRK 751
Query: 690 TTNSSLEE-------------------------------------------------IMD 700
+ + S E +
Sbjct: 752 SRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMST 811
Query: 701 KAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMV-EKDIRMA 759
K Y+++ + ++Q++ R ++ WK + H+++ ++H++L + ++ D +
Sbjct: 812 KMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYP 871
Query: 760 RFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLG 819
+SG LP + + I++ K + L N L ++ + Q+ +G L
Sbjct: 872 GAVLSGNLPDLKIHINEDK---ISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQRGSLQ 928
Query: 820 TSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVIL 879
S++ T +++ E Q + + N I++L F
Sbjct: 929 DSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTN---A 985
Query: 880 EFTKQQKEEDTILVFNVTQLGTEATMRT----FDLTVVSYLKKISLDY------------ 923
F K+ + + L V L TM+T FDL + S+ K +S D
Sbjct: 986 HFVKRPYDAEVSL--TVHGLLLVDTMQTYGADFDLLMASH-KNLSFDIPTGSLRDSRAQS 1042
Query: 924 --------HEIEGSKRKPLHLISSS-----DKPGLDLLKVEYIKADKNGPSFQTAFGKTE 970
H +G+ S S K L+K+EY PS T
Sbjct: 1043 PVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLIKLEYQFVSSECPSMN--LDSTL 1100
Query: 971 QTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAI 1030
Q + + ++L+++L + +V I +L P + +S + ++ T
Sbjct: 1101 QVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY 1160
Query: 1031 VSSRDSDIIDFRLFAKLNAFCVIVCNEK--NNIAEIKIQGLDSSLSLQSRKQSLFARLEN 1088
+ + + RL L + EK IA I G ++S+ S + L
Sbjct: 1161 EQNTEVAVEIHRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGS-TFDMNGSLGC 1219
Query: 1089 IIVTDVDPKTVHKKAVSIMGNEVFRFNL--DL---------YPDA--TEGDLYT--DMSK 1133
+ + D+ V + V +GN V N+ D+ DA TE +T + SK
Sbjct: 1220 LQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVRMEDAALTEALSFTFVERSK 1279
Query: 1134 VDGVLSLNVGCIQIVYLHKFLMSLL--------NFLNNFQTAKESLSAATAQAAERAATS 1185
+ L+L + + + KFL L NF ++A ++ A +
Sbjct: 1280 QECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEM 1339
Query: 1186 VK----------------------DLAQR---SFRVSINIDLKAPVIVIPQSSISTNAVV 1220
V DLA + ++ +NI++++PV+ IP+ S +V
Sbjct: 1340 VSLFETPRKTREPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLV 1399
Query: 1221 VDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLY 1259
LG I + N F DE DR+ V++ + LY
Sbjct: 1400 GHLGQIFIQN-FVAGDDESR-----SDRLQVEIKDIKLY 1432
Score = 144 bits (362), Expect = 2e-33
Identities = 139/573 (24%), Positives = 260/573 (45%), Gaps = 61/573 (10%)
Query: 3141 LSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDV 3200
L+GI + + Q + L + +QVDNQL G P + + V P + E P + V
Sbjct: 3829 LTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLY-VTPLSNENEVIETGPAVQV 3887
Query: 3201 SVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQD 3260
+ + ++ + +K+ M+ Q ++I++ L +++ F E+E +++
Sbjct: 3888 NAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFG-YDQAESE------VEKY 3940
Query: 3261 IDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHSVNL 3320
+ L+ + E T I +FE+ IS ++ LS+ S+K ++ A+ S
Sbjct: 3941 DENLHEKTAEQGGTP--IRYYFENLKISIPQIKLSVFT------SNKLPLDLKALKS--- 3989
Query: 3321 LLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVL 3380
++G L +D + L + + + ++ +I +++H+ E+ L Q ++ +D L
Sbjct: 3990 ---TLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFL 4046
Query: 3381 GNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITG 3440
GNP GL+ +SEGV L G V G L + G + ++ G
Sbjct: 4047 GNPMGLLNDVSEGVTGLIK---YGNVGG--------------LIRNVTHGVSNSAAKFAG 4089
Query: 3441 SVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGA 3500
++ GL TMD +Q + RE + G+ L G G G++GG+T +IT VEG
Sbjct: 4090 TLSDGLGK-TMDNRHQSE-REYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGV 4147
Query: 3501 KKE-GAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAEST---EEVSSLRPPR- 3555
K E G +GF G+GKGLVG V +P G +D AS T Q ++ A + + +R PR
Sbjct: 4148 KTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRC 4207
Query: 3556 LIHEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKE 3615
G++ Y ++EG + L ++ E + A+ ++++++ V +K
Sbjct: 4208 CTGPQGLLPRYSESQAEGQEQLFKLTDNIQDE---FFIAVENIDSYCVLISSKAVYFLKS 4264
Query: 3616 VEILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGC--------VRK 3667
+ + + + ++D ++ VS++ K+ V+ + K S + G
Sbjct: 4265 GDYVDREAIFLEVKYDD-LYHCLVSKDHGKVYVQ---VTKKAVSTSSGVSIPGPSHQKPM 4320
Query: 3668 VYLKDTATAERACNAIEDAQSTRQQQKLMKQSS 3700
V++K A + I A+S +Q+LM + S
Sbjct: 4321 VHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLS 4353
Score = 84.3 bits (207), Expect = 2e-15
Identities = 65/289 (22%), Positives = 140/289 (48%), Gaps = 17/289 (5%)
Query: 947 LLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQS 1006
L+ + DK P F +++ + +++ V F+ L++L+ Q V +++ +D+ +
Sbjct: 1784 LVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHA 1843
Query: 1007 ISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKI 1066
+ + E + K + P A + S D ++ +L K+++ +++ + +A+ +
Sbjct: 1844 MRLPPEGILHNVKLE-----PHASMESGLQDPVNTKLDLKVHSLSLVLNKTTSELAKANV 1898
Query: 1067 QGLDSSLSLQSRKQSLFARLENIIVTDVDPK-TVHKKAVSIMGNEVFRFNLDLY--PDAT 1123
L + L + +L + ++ ++D+ +++ + G E F Y PD
Sbjct: 1899 SKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPL 1958
Query: 1124 EGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAA 1183
+ D +SL + +Q V+ +F ++ F+ +F ++ L Q A
Sbjct: 1959 L------RREHDIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGR---QRAAIEG 2009
Query: 1184 TSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQF 1232
+V+D AQR RV ++I+ APV++IP+SS S N +V +LG ++V N+F
Sbjct: 2010 QTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKF 2058
Score = 82.8 bits (203), Expect = 6e-15
Identities = 66/305 (21%), Positives = 147/305 (48%), Gaps = 20/305 (6%)
Query: 1447 EPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1506
EP ++ S D+ L+ + + D PEF + ++ + + V F LD+++ L+ +
Sbjct: 1770 EPKILVGKSKF-DDSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVV 1828
Query: 1507 FMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQ-KDVFDLKITAELNAF 1565
+DF F S+++ + P G ++ ++ +S S +D + K+ ++++
Sbjct: 1829 ILDF------FGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSL 1882
Query: 1566 NVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQS-IHKKAVSILGD 1624
++ + +A + + A + + + + + + ++ +++ + G+
Sbjct: 1883 SLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGE 1942
Query: 1625 EVFRFQLTLY--PDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTA 1682
E FQ Y PD + D ++S ++ +Q V+ +F ++ F+ +F
Sbjct: 1943 EALIFQTFKYGRPDPLLRREH------DIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQL 1996
Query: 1683 KEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIR 1742
++ L Q A +++D AQ+ R+L+DI APV++IP+SS S N ++A+LG ++
Sbjct: 1997 QDVLGR---QRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLK 2053
Query: 1743 VENKF 1747
V+NKF
Sbjct: 2054 VKNKF 2058
Score = 53.9 bits (128), Expect = 3e-06
Identities = 96/441 (21%), Positives = 173/441 (39%), Gaps = 70/441 (15%)
Query: 2619 YIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTADVLHSRISGEIMEL-------- 2670
+ I+L P++ + NLLP L + ++G L G A LH+ + + +EL
Sbjct: 3151 HTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEA-ALHTADTSQNIELGVSLENFP 3209
Query: 2671 ----VLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRIGSRMVLSVF 2726
+L+ +N+ R+ D + + + + R GS + +
Sbjct: 3210 LCKELLIPPGTQNYMVRMRLYDV------------NRRQLNLTIRIVCRAEGSLKIF-IS 3256
Query: 2727 SPYWLINKTTRVLQYRSEDIHVKHPADFRD--------IILFSFKKKNIFTKNKVQLKIS 2778
+PYWLINKT L +R ++ F + +LF + K N ++I
Sbjct: 3257 APYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKE--QPNLCTMRIG 3314
Query: 2779 TS-------AWSSSFSLDTVGSYGCVKCPAN----NMEYLVGVSIK--MSSFNLSRIVTL 2825
W FSLD +K + Y +G+ +K + + +V
Sbjct: 3315 RGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIF 3374
Query: 2826 TPFCTIANKSSLELEVGEIA-SDGSMPTNKWNYIAS---SECLPFWPES-LSGKLCVR-- 2878
P + NKSS +L + + G N YI++ S + WP + LCVR
Sbjct: 3375 APRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLM 3434
Query: 2879 -VVGCEGSSKPFFYNRQDNGTLLSLEDLNGG---ILVDVNTAEHSTVITFSDYHEGSAPA 2934
V C S F ++N +++ D G + V++ + I+FSD + P
Sbjct: 3435 DVPNCIWSGG--FEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPF 3492
Query: 2935 LIMNHTPWDILTYKQSGSPEEMV---LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLL 2991
I N + ++ + Q G E + + P + +AW +PT +T T G ++
Sbjct: 3493 RIDNFSKVPVV-FTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLT-VKGAGSSEI- 3549
Query: 2992 KDGCGQFPYDANIQIHWVSFL 3012
C + N Q+++ +F+
Sbjct: 3550 --NCNMNDFQDNRQLYYENFI 3568
Score = 52.0 bits (123), Expect = 1e-05
Identities = 122/611 (19%), Positives = 236/611 (38%), Gaps = 138/611 (22%)
Query: 1274 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL---FRILT--ENL 1328
++ N+ + R L + K P + G+L + + +N++ ++ L F +LT E
Sbjct: 848 VVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMK 907
Query: 1329 CEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEI 1388
T+ +K+ P+ ++ G S+ V + ++ + R V + + LL E
Sbjct: 908 TSDTQIKEKIFPQEEQRG--------SLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEF 959
Query: 1389 KEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYD----MTAKAYLKKISMQCF--DFT 1442
K V + E GR + L V + YD +T L +MQ + DF
Sbjct: 960 K--VNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFD 1017
Query: 1443 -------------------DSKGE-PLHIINSSNVTD----------------------E 1460
DS+ + P+ N +++TD E
Sbjct: 1018 LLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQE 1077
Query: 1461 PLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEP 1520
L+K+ S+ P DST Q + + +LD++L+ E ++ + FL + P +
Sbjct: 1078 SLIKLEYQFVSSECPSMNL--DSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKD 1135
Query: 1521 SSSEKESELKPLVGE-SRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVC--------- 1570
S + PL+ + RS + + +++ ++ E++ N+ +
Sbjct: 1136 DLSPQ-----PLMTDFERSFREQGTYQSTYEQNT---EVAVEIHRLNLLLLRTVGMANRE 1187
Query: 1571 DQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEV---- 1626
IA I G ++S+ D+ L + +M++ ++ + V +G+ V
Sbjct: 1188 KYGRKIATASIGGTKVNVSMG-STFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYEN 1246
Query: 1627 -------FRFQLTLYPDATEGEA----YADMSKVDGKLSFKVGCIQIVYVHKFF----MS 1671
F DA EA + + SK + L+ K+ + + KF +S
Sbjct: 1247 IISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLS 1306
Query: 1672 LLNFLNNFQTAKEALST--ATVQAAERAASSMK------------------------DLA 1705
+ NF+ ++ +T TV A + A S DLA
Sbjct: 1307 MDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREPFILEENEIYGFDLA 1366
Query: 1706 QK---SFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVID 1762
+ +L+++IN+++PV+ IP+ SP ++ LG I ++N F E S D
Sbjct: 1367 SSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQN-FVAGDDESRS-----D 1420
Query: 1763 KMNIELTQLKL 1773
++ +E+ +KL
Sbjct: 1421 RLQVEIKDIKL 1431
Score = 39.7 bits (91), Expect = 0.056
Identities = 86/375 (22%), Positives = 148/375 (39%), Gaps = 50/375 (13%)
Query: 1274 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTE 1333
L P L+ V RNL H VP + I G+L S++ SL+ L+ +L NL E E
Sbjct: 2201 LTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGLLENNLGEPIE 2260
Query: 1334 DLDKVKPRVQETGEIKEP-LEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNF---EIK 1389
+ ++P ++++P + +S +V+ L +D++N+ L + K
Sbjct: 2261 EF--MRPY-----DLQDPRIHTVLSGEVYTCMCFL---------IDMVNVSLELKDPKRK 2304
Query: 1390 EVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD--FTDSKGE 1447
E +L + KK + L+E + T L SM FD + K
Sbjct: 2305 EGAGSLARFDFKKCKLLYE------------SFSNQTKSINLVSHSMMAFDTRYAGQKTS 2352
Query: 1448 PLHIINSSNVTDEPLLKMLLTKADSD-GPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1506
P + N + +P T+ F++ DS+ V +L + L + LL
Sbjct: 2353 P-GMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSS--CFTVVLNNLRVFLIFDWLLL 2409
Query: 1507 FMDFLSSAAPF--------SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKI 1558
DFL + + S +S ES + P +S + K S +S + ++K+
Sbjct: 2410 VHDFLHTPSDIKKQNHVTPSRHRNSSSESAIVPKTVKS-GVVTKRSSLPVSNERHLEVKV 2468
Query: 1559 TAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTD--VFARLKDIIVMNVDLQSIHK 1616
F V + D C + I ++ KP+ D L I V + L + H
Sbjct: 2469 NVTGTEF-VVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHD 2527
Query: 1617 KAVSILGDEVFRFQL 1631
A+SI+ + +L
Sbjct: 2528 TALSIVDPVQIQMEL 2542
>gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens]
Length = 4388
Score = 234 bits (596), Expect = 2e-60
Identities = 313/1479 (21%), Positives = 604/1479 (40%), Gaps = 268/1479 (18%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61
+LE +VA +LN +LG YV NLN QL + + G V L+NL +K++AL EL++PF+VKAG
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEA 121
I K+TL+IP+ + + V ++ L+L+ P ++ KE+ ++ K+ L +EE
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 122 LQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGE 181
+ ++ + E+ + + T++++N+++KI D+H+++ED VT+P P +FG+ +
Sbjct: 121 WKN--DRQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKN 178
Query: 182 LSLLTANEHWTPCILNEADKIIYKLIRLD--SLSAYWNVNCSMSYQRSREQILDQLKNEI 239
+S+ A +NE + + + +LD S YW+V+C++ + ++ + + +
Sbjct: 179 VSMQNA--------VNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQMELQEAMARSM 230
Query: 240 LTSGNIPPNYQYIFQPISASAKLYMNPYAESELK---TPKLDCNIEIQNIAIELTKPQYL 296
+ ++ Y+ +P+ ASA L N ++ L+ +P++DC+I+++ I ++L++ QY
Sbjct: 231 ESR-----SHHYVLEPVFASALLKRN-CSKKPLRSRHSPRIDCDIQLETIPLKLSQLQYR 284
Query: 297 SMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIK 356
+++ L+ ++ R +R++KP + + N R WW +A+++ L IR + +W +
Sbjct: 285 QIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANL-YEIREQRKRCTWDFML 343
Query: 357 KHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILAR---------QQAQV 407
+ SY Y NKL +S + ++E+ +E+ + + R Q+
Sbjct: 344 HRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEELA 403
Query: 408 EVIRSGQKLRKKSADTGEKRGG----------WFSGLWGKKESKK------------KDE 445
E +R Q + + GG WF G WG ++ + +
Sbjct: 404 ESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPG-WGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 446 ESLIPETI-------------DDLMTPEEKDKLFTAIGYSESTHNLTL-------PKQYV 485
E IPE I + T ++D +F + +TL P+
Sbjct: 463 EQWIPEEILGTEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQMNE 522
Query: 486 AHIMTL-----KLVSTSVTIRENKNIPEILKIQIIGL--------GTQ----VSQRPGAQ 528
+ M L KL++ S+ R + +L +++ GL GT V P +
Sbjct: 523 SAFMQLEFSDVKLLAESLPRRNS----SLLSVRLGGLFLRDLATEGTMFPLLVFPNPQKE 578
Query: 529 ALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQP 588
+V GL+ S D + ++ +E NP S ++ L V ++P
Sbjct: 579 VGRVSQSF------GLQTTSADRSDHYPAADPDGPVFEMLYERNPAHSHFERRLNVSTRP 632
Query: 589 VEVIYDAKTVNAVVEFFQSNK------GLDLE---QITSATLMKLEEIKERTATGLTH-- 637
+ +IY+ + + V +FF K G E ++ A + ++K +T +
Sbjct: 633 LNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQTKAEIRQTL 692
Query: 638 -------IIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGTFQL-NSKDQGLQK 689
IE K +R+++ ++ P F + L+++D G L N++D +K
Sbjct: 693 DRLLVGDFIEESKRWTVRLDISAPQVIFPD-DFKFKNPVLVVVDLGRMLLTNTQDNSRRK 751
Query: 690 TTNSSLEE-------------------------------------------------IMD 700
+ + S E +
Sbjct: 752 SRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQLQAHLMST 811
Query: 701 KAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMV-EKDIRMA 759
K Y+++ + ++Q++ R ++ WK + H+++ ++H++L + ++ D +
Sbjct: 812 KMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYP 871
Query: 760 RFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLG 819
+SG LP + + I++ K + L N L ++ + Q+ +G L
Sbjct: 872 GAVLSGNLPDLKIHINEDK---ISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQRGSLQ 928
Query: 820 TSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVIL 879
S++ T +++ E Q + + N I++L F
Sbjct: 929 DSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTN---A 985
Query: 880 EFTKQQKEEDTILVFNVTQLGTEATMRT----FDLTVVSYLKKISLDY------------ 923
F K+ + + L V L TM+T FDL + S+ K +S D
Sbjct: 986 HFVKRPYDAEVSL--TVHGLLLVDTMQTYGADFDLLMASH-KNLSFDIPTGSLRDSRAQS 1042
Query: 924 --------HEIEGSKRKPLHLISSS-----DKPGLDLLKVEYIKADKNGPSFQTAFGKTE 970
H +G+ S S K L+K+EY PS T
Sbjct: 1043 PVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQESLIKLEYQFVSSECPSMN--LDSTL 1100
Query: 971 QTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAI 1030
Q + + ++L+++L + +V I +L P + +S + ++ T
Sbjct: 1101 QVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY 1160
Query: 1031 VSSRDSDIIDFRLFAKLNAFCVIVCNEK--NNIAEIKIQGLDSSLSLQSRKQSLFARLEN 1088
+ + + RL L + EK IA I G ++S+ S + L
Sbjct: 1161 EQNTEVAVEIHRLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSMGS-TFDMNGSLGC 1219
Query: 1089 IIVTDVDPKTVHKKAVSIMGNEVFRFNL--DL---------YPDA--TEGDLYT--DMSK 1133
+ + D+ V + V +GN V N+ D+ DA TE +T + SK
Sbjct: 1220 LQLMDLTQDNVKNQYVVSIGNSVGYENIISDIGYFESVFVRMEDAALTEALSFTFVERSK 1279
Query: 1134 VDGVLSLNVGCIQIVYLHKFLMSLL--------NFLNNFQTAKESLSAATAQAAERAATS 1185
+ L+L + + + KFL L NF ++A ++ A +
Sbjct: 1280 QECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRGMLKSAATKVTTVLATKTAEYSEM 1339
Query: 1186 VK----------------------DLAQR---SFRVSINIDLKAPVIVIPQSSISTNAVV 1220
V DLA + ++ +NI++++PV+ IP+ S +V
Sbjct: 1340 VSLFETPRKTREPFILEENEIYGFDLASSHLDTVKLILNINIESPVVSIPRKPGSPELLV 1399
Query: 1221 VDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLY 1259
LG I + N F DE DR+ V++ + LY
Sbjct: 1400 GHLGQIFIQN-FVAGDDESR-----SDRLQVEIKDIKLY 1432
Score = 144 bits (362), Expect = 2e-33
Identities = 139/573 (24%), Positives = 260/573 (45%), Gaps = 61/573 (10%)
Query: 3141 LSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDV 3200
L+GI + + Q + L + +QVDNQL G P + + V P + E P + V
Sbjct: 3854 LTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLY-VTPLSNENEVIETGPAVQV 3912
Query: 3201 SVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQD 3260
+ + ++ + +K+ M+ Q ++I++ L +++ F E+E +++
Sbjct: 3913 NAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFFG-YDQAESE------VEKY 3965
Query: 3261 IDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHSVNL 3320
+ L+ + E T I +FE+ IS ++ LS+ S+K ++ A+ S
Sbjct: 3966 DENLHEKTAEQGGTP--IRYYFENLKISIPQIKLSVFT------SNKLPLDLKALKS--- 4014
Query: 3321 LLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVL 3380
++G L +D + L + + + ++ +I +++H+ E+ L Q ++ +D L
Sbjct: 4015 ---TLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGSVDFL 4071
Query: 3381 GNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITG 3440
GNP GL+ +SEGV L G V G L + G + ++ G
Sbjct: 4072 GNPMGLLNDVSEGVTGLIK---YGNVGG--------------LIRNVTHGVSNSAAKFAG 4114
Query: 3441 SVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGA 3500
++ GL TMD +Q + RE + G+ L G G G++GG+T +IT VEG
Sbjct: 4115 TLSDGLGK-TMDNRHQSE-REYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGV 4172
Query: 3501 KKE-GAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAEST---EEVSSLRPPR- 3555
K E G +GF G+GKGLVG V +P G +D AS T Q ++ A + + +R PR
Sbjct: 4173 KTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRC 4232
Query: 3556 LIHEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKE 3615
G++ Y ++EG + L ++ E + A+ ++++++ V +K
Sbjct: 4233 CTGPQGLLPRYSESQAEGQEQLFKLTDNIQDE---FFIAVENIDSYCVLISSKAVYFLKS 4289
Query: 3616 VEILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGC--------VRK 3667
+ + + + ++D ++ VS++ K+ V+ + K S + G
Sbjct: 4290 GDYVDREAIFLEVKYDD-LYHCLVSKDHGKVYVQ---VTKKAVSTSSGVSIPGPSHQKPM 4345
Query: 3668 VYLKDTATAERACNAIEDAQSTRQQQKLMKQSS 3700
V++K A + I A+S +Q+LM + S
Sbjct: 4346 VHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLS 4378
Score = 84.3 bits (207), Expect = 2e-15
Identities = 65/289 (22%), Positives = 140/289 (48%), Gaps = 17/289 (5%)
Query: 947 LLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQS 1006
L+ + DK P F +++ + +++ V F+ L++L+ Q V +++ +D+ +
Sbjct: 1784 LVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHA 1843
Query: 1007 ISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKI 1066
+ + E + K + P A + S D ++ +L K+++ +++ + +A+ +
Sbjct: 1844 MRLPPEGILHNVKLE-----PHASMESGLQDPVNTKLDLKVHSLSLVLNKTTSELAKANV 1898
Query: 1067 QGLDSSLSLQSRKQSLFARLENIIVTDVDPK-TVHKKAVSIMGNEVFRFNLDLY--PDAT 1123
L + L + +L + ++ ++D+ +++ + G E F Y PD
Sbjct: 1899 SKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGEEALIFQTFKYGRPDPL 1958
Query: 1124 EGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAA 1183
+ D +SL + +Q V+ +F ++ F+ +F ++ L Q A
Sbjct: 1959 L------RREHDIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGR---QRAAIEG 2009
Query: 1184 TSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQF 1232
+V+D AQR RV ++I+ APV++IP+SS S N +V +LG ++V N+F
Sbjct: 2010 QTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKF 2058
Score = 82.8 bits (203), Expect = 6e-15
Identities = 66/305 (21%), Positives = 147/305 (48%), Gaps = 20/305 (6%)
Query: 1447 EPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1506
EP ++ S D+ L+ + + D PEF + ++ + + V F LD+++ L+ +
Sbjct: 1770 EPKILVGKSKF-DDSLVHINIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVV 1828
Query: 1507 FMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQ-KDVFDLKITAELNAF 1565
+DF F S+++ + P G ++ ++ +S S +D + K+ ++++
Sbjct: 1829 ILDF------FGIGSTADNHAMRLPPEGILHNVKLEPHASMESGLQDPVNTKLDLKVHSL 1882
Query: 1566 NVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQS-IHKKAVSILGD 1624
++ + +A + + A + + + + + + ++ +++ + G+
Sbjct: 1883 SLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTCHGEFYRERFTTSGE 1942
Query: 1625 EVFRFQLTLY--PDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTA 1682
E FQ Y PD + D ++S ++ +Q V+ +F ++ F+ +F
Sbjct: 1943 EALIFQTFKYGRPDPLLRREH------DIRVSLRMASVQYVHTQRFQAEVVAFIQHFTQL 1996
Query: 1683 KEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIR 1742
++ L Q A +++D AQ+ R+L+DI APV++IP+SS S N ++A+LG ++
Sbjct: 1997 QDVLGR---QRAAIEGQTVRDQAQRCSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLK 2053
Query: 1743 VENKF 1747
V+NKF
Sbjct: 2054 VKNKF 2058
Score = 53.9 bits (128), Expect = 3e-06
Identities = 96/441 (21%), Positives = 173/441 (39%), Gaps = 70/441 (15%)
Query: 2619 YIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTADVLHSRISGEIMEL-------- 2670
+ I+L P++ + NLLP L + ++G L G A LH+ + + +EL
Sbjct: 3176 HTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEA-ALHTADTSQNIELGVSLENFP 3234
Query: 2671 ----VLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRIGSRMVLSVF 2726
+L+ +N+ R+ D + + + + R GS + +
Sbjct: 3235 LCKELLIPPGTQNYMVRMRLYDV------------NRRQLNLTIRIVCRAEGSLKIF-IS 3281
Query: 2727 SPYWLINKTTRVLQYRSEDIHVKHPADFRD--------IILFSFKKKNIFTKNKVQLKIS 2778
+PYWLINKT L +R ++ F + +LF + K N ++I
Sbjct: 3282 APYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKE--QPNLCTMRIG 3339
Query: 2779 TS-------AWSSSFSLDTVGSYGCVKCPAN----NMEYLVGVSIK--MSSFNLSRIVTL 2825
W FSLD +K + Y +G+ +K + + +V
Sbjct: 3340 RGIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIF 3399
Query: 2826 TPFCTIANKSSLELEVGEIA-SDGSMPTNKWNYIAS---SECLPFWPES-LSGKLCVR-- 2878
P + NKSS +L + + G N YI++ S + WP + LCVR
Sbjct: 3400 APRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLM 3459
Query: 2879 -VVGCEGSSKPFFYNRQDNGTLLSLEDLNGG---ILVDVNTAEHSTVITFSDYHEGSAPA 2934
V C S F ++N +++ D G + V++ + I+FSD + P
Sbjct: 3460 DVPNCIWSGG--FEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPF 3517
Query: 2935 LIMNHTPWDILTYKQSGSPEEMV---LLPRQARLFAWADPTGTRKLTWTYAANVGEHDLL 2991
I N + ++ + Q G E + + P + +AW +PT +T T G ++
Sbjct: 3518 RIDNFSKVPVV-FTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLT-VKGAGSSEI- 3574
Query: 2992 KDGCGQFPYDANIQIHWVSFL 3012
C + N Q+++ +F+
Sbjct: 3575 --NCNMNDFQDNRQLYYENFI 3593
Score = 52.0 bits (123), Expect = 1e-05
Identities = 122/611 (19%), Positives = 236/611 (38%), Gaps = 138/611 (22%)
Query: 1274 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLL---FRILT--ENL 1328
++ N+ + R L + K P + G+L + + +N++ ++ L F +LT E
Sbjct: 848 VVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMK 907
Query: 1329 CEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEI 1388
T+ +K+ P+ ++ G S+ V + ++ + R V + + LL E
Sbjct: 908 TSDTQIKEKIFPQEEQRG--------SLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEF 959
Query: 1389 KEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYD----MTAKAYLKKISMQCF--DFT 1442
K V + E GR + L V + YD +T L +MQ + DF
Sbjct: 960 K--VNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFD 1017
Query: 1443 -------------------DSKGE-PLHIINSSNVTD----------------------E 1460
DS+ + P+ N +++TD E
Sbjct: 1018 LLMASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLTDGATLNDRSATSVSLDKILTKEQE 1077
Query: 1461 PLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEP 1520
L+K+ S+ P DST Q + + +LD++L+ E ++ + FL + P +
Sbjct: 1078 SLIKLEYQFVSSECPSMNL--DSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKD 1135
Query: 1521 SSSEKESELKPLVGE-SRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVC--------- 1570
S + PL+ + RS + + +++ ++ E++ N+ +
Sbjct: 1136 DLSPQ-----PLMTDFERSFREQGTYQSTYEQNT---EVAVEIHRLNLLLLRTVGMANRE 1187
Query: 1571 DQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEV---- 1626
IA I G ++S+ D+ L + +M++ ++ + V +G+ V
Sbjct: 1188 KYGRKIATASIGGTKVNVSMG-STFDMNGSLGCLQLMDLTQDNVKNQYVVSIGNSVGYEN 1246
Query: 1627 -------FRFQLTLYPDATEGEA----YADMSKVDGKLSFKVGCIQIVYVHKFF----MS 1671
F DA EA + + SK + L+ K+ + + KF +S
Sbjct: 1247 IISDIGYFESVFVRMEDAALTEALSFTFVERSKQECFLNLKMASLHYNHSAKFLKELTLS 1306
Query: 1672 LLNFLNNFQTAKEALST--ATVQAAERAASSMK------------------------DLA 1705
+ NF+ ++ +T TV A + A S DLA
Sbjct: 1307 MDELEENFRGMLKSAATKVTTVLATKTAEYSEMVSLFETPRKTREPFILEENEIYGFDLA 1366
Query: 1706 QK---SFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVID 1762
+ +L+++IN+++PV+ IP+ SP ++ LG I ++N F E S D
Sbjct: 1367 SSHLDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQN-FVAGDDESRS-----D 1420
Query: 1763 KMNIELTQLKL 1773
++ +E+ +KL
Sbjct: 1421 RLQVEIKDIKL 1431
Score = 39.7 bits (91), Expect = 0.056
Identities = 86/375 (22%), Positives = 148/375 (39%), Gaps = 50/375 (13%)
Query: 1274 LLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTE 1333
L P L+ V RNL H VP + I G+L S++ SL+ L+ +L NL E E
Sbjct: 2201 LTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLYKYKLIRGLLENNLGEPIE 2260
Query: 1334 DLDKVKPRVQETGEIKEP-LEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNF---EIK 1389
+ ++P ++++P + +S +V+ L +D++N+ L + K
Sbjct: 2261 EF--MRPY-----DLQDPRIHTVLSGEVYTCMCFL---------IDMVNVSLELKDPKRK 2304
Query: 1390 EVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD--FTDSKGE 1447
E +L + KK + L+E + T L SM FD + K
Sbjct: 2305 EGAGSLARFDFKKCKLLYE------------SFSNQTKSINLVSHSMMAFDTRYAGQKTS 2352
Query: 1448 PLHIINSSNVTDEPLLKMLLTKADSD-GPEFKTIHDSTKQRLKVSFASLDLVLHLEALLS 1506
P + N + +P T+ F++ DS+ V +L + L + LL
Sbjct: 2353 P-GMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTKDSS--CFTVVLNNLRVFLIFDWLLL 2409
Query: 1507 FMDFLSSAAPF--------SEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKI 1558
DFL + + S +S ES + P +S + K S +S + ++K+
Sbjct: 2410 VHDFLHTPSDIKKQNHVTPSRHRNSSSESAIVPKTVKS-GVVTKRSSLPVSNERHLEVKV 2468
Query: 1559 TAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTD--VFARLKDIIVMNVDLQSIHK 1616
F V + D C + I ++ KP+ D L I V + L + H
Sbjct: 2469 NVTGTEF-VVIEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHD 2527
Query: 1617 KAVSILGDEVFRFQL 1631
A+SI+ + +L
Sbjct: 2528 TALSIVDPVQIQMEL 2542
>gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens]
Length = 4022
Score = 107 bits (268), Expect = 2e-22
Identities = 69/264 (26%), Positives = 121/264 (45%), Gaps = 13/264 (4%)
Query: 3309 KQEMFAVHSVNLLLKSIGATLT---DVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQ 3365
K + VNLL+ SI A+L D + +E F QL+ ++ HY+
Sbjct: 3584 KLRKLVIQPVNLLV-SIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAG 3642
Query: 3366 FLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFG 3425
L + +V LD+LG+P L+R + GV F P++G +GP F G+ G S
Sbjct: 3643 ALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVK 3702
Query: 3426 HTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGV 3485
H G ++ + S+ + + +++D+E+ ++ E + P G+ L +G +
Sbjct: 3703 HISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISL 3762
Query: 3486 VGGVTGIITKPVEGAKKEG---------AAGFFKGIGKGLVGAVARPTGGIVDMASSTFQ 3536
+G + GI+ +P++ +K A G G+GKG++G +P GG ++ S T
Sbjct: 3763 LGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGY 3822
Query: 3537 GIQRAAESTEEVSSLRPPRLIHED 3560
GI A ++ P +H D
Sbjct: 3823 GILHGAGLSQLPKQRHQPSDLHAD 3846
Score = 84.0 bits (206), Expect = 3e-15
Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 17/213 (7%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60
+LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGL--YLLVVPGASIKYDAVKEEKSLQDVKQKELSRI 118
I +L + +PW L E VV T+ + L + G +++ + + + S I
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 119 E-EALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFG 176
+ +Q+AA D +V+ L +V+ NV + I ++ +KY EDD+ LS
Sbjct: 121 KPRRMQQAAPTDPD---LPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVN 172
Query: 177 VTLGELSLLTANEHWTPCI--LNEADKIIYKLI 207
+T E T E W ++ D ++ K+I
Sbjct: 173 ITSAE--CYTVGELWDRAFMDISATDLVLRKVI 203
>gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens]
Length = 3997
Score = 107 bits (268), Expect = 2e-22
Identities = 69/264 (26%), Positives = 121/264 (45%), Gaps = 13/264 (4%)
Query: 3309 KQEMFAVHSVNLLLKSIGATLT---DVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQ 3365
K + VNLL+ SI A+L D + +E F QL+ ++ HY+
Sbjct: 3559 KLRKLVIQPVNLLV-SIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAG 3617
Query: 3366 FLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFG 3425
L + +V LD+LG+P L+R + GV F P++G +GP F G+ G S
Sbjct: 3618 ALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVK 3677
Query: 3426 HTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGV 3485
H G ++ + S+ + + +++D+E+ ++ E + P G+ L +G +
Sbjct: 3678 HISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISL 3737
Query: 3486 VGGVTGIITKPVEGAKKEG---------AAGFFKGIGKGLVGAVARPTGGIVDMASSTFQ 3536
+G + GI+ +P++ +K A G G+GKG++G +P GG ++ S T
Sbjct: 3738 LGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGY 3797
Query: 3537 GIQRAAESTEEVSSLRPPRLIHED 3560
GI A ++ P +H D
Sbjct: 3798 GILHGAGLSQLPKQRHQPSDLHAD 3821
Score = 84.0 bits (206), Expect = 3e-15
Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 17/213 (7%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60
+LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGL--YLLVVPGASIKYDAVKEEKSLQDVKQKELSRI 118
I +L + +PW L E VV T+ + L + G +++ + + + S I
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 119 E-EALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFG 176
+ +Q+AA D +V+ L +V+ NV + I ++ +KY EDD+ LS
Sbjct: 121 KPRRMQQAAPTDPD---LPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVN 172
Query: 177 VTLGELSLLTANEHWTPCI--LNEADKIIYKLI 207
+T E T E W ++ D ++ K+I
Sbjct: 173 ITSAE--CYTVGELWDRAFMDISATDLVLRKVI 203
>gi|119874215 vacuolar protein sorting 13B isoform 4 [Homo sapiens]
Length = 415
Score = 84.0 bits (206), Expect = 3e-15
Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 17/213 (7%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60
+LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGL--YLLVVPGASIKYDAVKEEKSLQDVKQKELSRI 118
I +L + +PW L E VV T+ + L + G +++ + + + S I
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 119 E-EALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFG 176
+ +Q+AA D +V+ L +V+ NV + I ++ +KY EDD+ LS
Sbjct: 121 KPRRMQQAAPTDPD---LPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVN 172
Query: 177 VTLGELSLLTANEHWTPCI--LNEADKIIYKLI 207
+T E T E W ++ D ++ K+I
Sbjct: 173 ITSAE--CYTVGELWDRAFMDISATDLVLRKVI 203
>gi|35493725 vacuolar protein sorting 13B isoform 3 [Homo sapiens]
Length = 863
Score = 84.0 bits (206), Expect = 3e-15
Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 17/213 (7%)
Query: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENAL-SELDVPFKVKAG 60
+LES V +L ++ Y++NL S L+L +WGG+V L L++K + L EL +PF +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 61 QIDKLTLKIPWKNLYGEAVVATLEGL--YLLVVPGASIKYDAVKEEKSLQDVKQKELSRI 118
I +L + +PW L E VV T+ + L + G +++ + + + S I
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 119 E-EALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKY-EDDVTDPKRPLSFG 176
+ +Q+AA D +V+ L +V+ NV + I ++ +KY EDD+ LS
Sbjct: 121 KPRRMQQAAPTDPD---LPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIV-----LSVN 172
Query: 177 VTLGELSLLTANEHWTPCI--LNEADKIIYKLI 207
+T E T E W ++ D ++ K+I
Sbjct: 173 ITSAE--CYTVGELWDRAFMDISATDLVLRKVI 203
>gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens]
Length = 2078
Score = 51.6 bits (122), Expect = 1e-05
Identities = 51/221 (23%), Positives = 103/221 (46%), Gaps = 19/221 (8%)
Query: 10 LLNRFLGDYV-ENLNKSQLKLGIWGGNVALDNLQIKENALSEL----DVPFKVKAGQIDK 64
LL R+LG ++ E L+ QL L ++ G +L + + + L+E+ D P +V G I
Sbjct: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
Query: 65 LTLKIPWKNLYGEAVVATLEGLYLLVVP------GASIKYDAVKEEKSLQDVKQKELSRI 118
++L +PW +L + + GL ++ P G+ Y + S+Q K+ ++
Sbjct: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSFMTSSMQLAKECLSQKL 136
Query: 119 EEALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVT 178
+ + E +P E + F E + T V++ V+V D ++ E + K + +
Sbjct: 137 TD---EQGEGSQPFEG-LEKFAETIET-VLRRVKVTFIDTVLRIEHVPENSKTGTALEIR 191
Query: 179 LGELSLL--TANEHWTPCILNEADKIIYKLIRLDSLSAYWN 217
+ TA+E + +++ +KL++L +S +W+
Sbjct: 192 IERTVYCDETADES-SGINVHQPTAFAHKLLQLSGVSLFWD 231
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 41.2 bits (95), Expect = 0.019
Identities = 33/141 (23%), Positives = 69/141 (48%), Gaps = 19/141 (13%)
Query: 342 HIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKV------SEEIQKEIQDLEKTLDV 395
+I + T+ +++ +R + ++ KN Q K+ EIQ ++DL++ L+
Sbjct: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 396 FNIILARQQAQVEVIRSGQKLRKKSADTG---EKRGGW-------FSGLWGKKESKKKDE 445
++L +QQ QVE R G++L+ SA E+ W +W ++E ++ E
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
Query: 446 ESLIPETIDDLMTPEEKDKLF 466
E + + +L E+++K++
Sbjct: 311 EKMCEQ---ELKIREQEEKMW 328
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 40.8 bits (94), Expect = 0.025
Identities = 33/141 (23%), Positives = 69/141 (48%), Gaps = 19/141 (13%)
Query: 342 HIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKV------SEEIQKEIQDLEKTLDV 395
+I + T+ +++ +R + ++ KN Q K+ EIQ ++DL++ L+
Sbjct: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 396 FNIILARQQAQVEVIRSGQKLRKKSADTG---EKRGGW-------FSGLWGKKESKKKDE 445
++L +QQ QVE R G++L+ SA E+ W +W ++E ++ E
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
Query: 446 ESLIPETIDDLMTPEEKDKLF 466
E + + +L E+++K++
Sbjct: 311 EKMCEQ---ELKIREQEEKMW 328
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 38.1 bits (87), Expect = 0.16
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 363 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 421
K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA
Sbjct: 210 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 268
Query: 422 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 462
+ ++ L ++E K +E I E + + EEK
Sbjct: 269 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEK 310
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 37.7 bits (86), Expect = 0.21
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 363 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 421
K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA
Sbjct: 222 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280
Query: 422 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 462
+ ++ L ++E K +E I E + + EEK
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 37.7 bits (86), Expect = 0.21
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 363 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 421
K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA
Sbjct: 222 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280
Query: 422 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 462
+ ++ L ++E K +E I E + + EEK
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 37.7 bits (86), Expect = 0.21
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 363 KSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSA- 421
K+ K+ K +L +S+ SE IQ +++L++ L+ ++L +QQ Q E G++L+ SA
Sbjct: 283 KNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 341
Query: 422 -DTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEK 462
+ ++ L ++E K +E I E + + EEK
Sbjct: 342 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 383
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 37.7 bits (86), Expect = 0.21
Identities = 43/207 (20%), Positives = 87/207 (42%), Gaps = 24/207 (11%)
Query: 1303 GHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDK---------------VKPRVQETGE 1347
G L +N SLNQE +NL+ + +E+ ++ +K + R +ETG
Sbjct: 977 GTLKEINASLNQEKMNLIQK--SESFANYIDEREKSISELSDQYKQEKLILLQRCEETGN 1034
Query: 1348 IKEPL--EISISQDVHDSKNTLT---TGVEEIRSVDIINMLLNF--EIKEVVVTLMKKSE 1400
E L + +Q+ + L T + E R ++ + F E +E + L E
Sbjct: 1035 AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEE 1094
Query: 1401 KKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNVTDE 1460
+ + EL +Q + +++ +K+ + + + + + +N +E
Sbjct: 1095 RNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENE 1154
Query: 1461 PLLKMLLTKADSDGPEFKTIHDSTKQR 1487
L+K++ TK + E + I +S K+R
Sbjct: 1155 QLMKVMKTKHECQNLESEPIRNSVKER 1181
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 37.4 bits (85), Expect = 0.28
Identities = 73/355 (20%), Positives = 144/355 (40%), Gaps = 58/355 (16%)
Query: 370 KNKLTQSKVSEEIQKEIQDLEKT---LDVFNIILARQQAQVEVIRSGQK----LRKKSAD 422
KN+L Q K ++Q + Q+LE T L + L +++ + S ++ K +
Sbjct: 444 KNELDQCK--SDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLN 501
Query: 423 TGEKRGGWFSGLWGKKESKKK------DEESLIPETIDDLMTPEEKDKLFTAIGYSESTH 476
T E+ SGL K + KK + + + + ++ L E+ G S+
Sbjct: 502 TVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEE---LIKDGSSKQKA 558
Query: 477 NLTLPKQYVAHIMTLKLVS----TSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKV 532
L + K ++++ + + T+V + +IPE + + + + + Q+L
Sbjct: 559 MLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILKE---QSLAA 615
Query: 533 EAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVI 592
E+K + + + D++ SL + T S+LKI SQ +
Sbjct: 616 ESKTVLQELINVLKTDLLSSLEMILSPTVVSILKI-----------------NSQLKHIF 658
Query: 593 YDAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLK 652
+ TV +E ++ +L+ S L E++E T + ++E++K NL
Sbjct: 659 KTSLTVADKIE----DQKKELDGFLSILCNNLHELQENT---ICSLVESQKQCG---NLT 708
Query: 653 PSYLVVPQTGFHHEKSDLLILDFGTFQ---LNSKDQGLQKTTNSSLEEIMDKAYD 704
+ QT H + +++ T + L K + +QK +S E I K+ D
Sbjct: 709 EDLKTIKQT---HSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKD 760
>gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
sapiens]
Length = 601
Score = 36.6 bits (83), Expect = 0.48
Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 30/114 (26%)
Query: 3404 GAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEL 3463
G QGP+ EG G RSL G G V+ + G+VG+
Sbjct: 67 GPAQGPQREEEGAP-GCRSLVGRGWGVGWAAVAEVQGTVGE------------------- 106
Query: 3464 SRQPRDFGDSLARGGKGFLRGVVGGVTG---IITKPVEGAKKEGAAGFFKGIGK 3514
R FG GG+G L VGG G + K G KEG +F G GK
Sbjct: 107 -RGALAFG-----GGRGLLAAGVGGAEGGCQVTRKIKRGRSKEGGGSWF-GAGK 153
>gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
sapiens]
Length = 601
Score = 36.2 bits (82), Expect = 0.62
Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 30/114 (26%)
Query: 3404 GAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEL 3463
G QGP+ EG G RSL G G V+ + G+VG+
Sbjct: 67 GPAQGPQREEEGAP-GCRSLVGRGWGVGWAAVAEVQGTVGE------------------- 106
Query: 3464 SRQPRDFGDSLARGGKGFLRGVVGGVTG---IITKPVEGAKKEGAAGFFKGIGK 3514
R FG GG+G L VGG G + K G KEG +F G GK
Sbjct: 107 -RGACAFG-----GGRGLLAAGVGGAEGGCQVTRKIKRGRSKEGGGSWF-GAGK 153
>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
Length = 849
Score = 36.2 bits (82), Expect = 0.62
Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 16/156 (10%)
Query: 1050 FCVIVCNEK-----NNIAEIKIQGLDSSLSLQSRKQSL------FARLENIIVTDVDPKT 1098
F V +C EK N + +++ S +S+++ +++L +LE + T P+
Sbjct: 622 FLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELETFPPPED 681
Query: 1099 VHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKV-DGVLSLNVGCIQIVYLHKFLMSL 1157
+H K V+ M V T L+ +M K+ ++ ++ V + FL L
Sbjct: 682 LHDKFVTKMSRFVISAKEQY---ETLSKLHENMEKLYQSIIGYYAIDVKKVSVEDFLTDL 738
Query: 1158 LNFLNNF-QTAKESLSAATAQAAERAATSVKDLAQR 1192
NF F Q KE++ A+ E+ K+LA+R
Sbjct: 739 NNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAER 774
>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
Length = 1193
Score = 36.2 bits (82), Expect = 0.62
Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 16/156 (10%)
Query: 1050 FCVIVCNEK-----NNIAEIKIQGLDSSLSLQSRKQSL------FARLENIIVTDVDPKT 1098
F V +C EK N + +++ S +S+++ +++L +LE + T P+
Sbjct: 885 FLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELETFPPPED 944
Query: 1099 VHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKV-DGVLSLNVGCIQIVYLHKFLMSL 1157
+H K V+ M V T L+ +M K+ ++ ++ V + FL L
Sbjct: 945 LHDKFVTKMSRFVISAKEQY---ETLSKLHENMEKLYQSIIGYYAIDVKKVSVEDFLTDL 1001
Query: 1158 LNFLNNF-QTAKESLSAATAQAAERAATSVKDLAQR 1192
NF F Q KE++ A+ E+ K+LA+R
Sbjct: 1002 NNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAER 1037
>gi|51988900 XPG-complementing protein [Homo sapiens]
Length = 1186
Score = 35.8 bits (81), Expect = 0.81
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 31/230 (13%)
Query: 687 LQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVE 746
LQ+T SS+ + +A D ++NV A+ E + + + +T Q + +
Sbjct: 583 LQET--SSIVSVPSEAVDN----VENVVSFNAKEHENFLETIQEQQTTESAGQDL---IS 633
Query: 747 LAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSS 806
+ KA+ +I + G + ISD++++ A+ PE +S
Sbjct: 634 IPKAVEPMEIDSEESESDGSFIEVQSVISDEELQ----------------AEFPE---TS 674
Query: 807 IPIISGGTKGLLGTSLLLDTVESES---DDEYFDAEDGEPQTCKSMKGSELKKAAEVPNE 863
P G + L+GT ESES D+ D DGEPQ + L + ++ E
Sbjct: 675 KPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLE 734
Query: 864 ELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVV 913
EL L ++ L+ KQQ+E V L ++ +R F + +
Sbjct: 735 ELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYI 784
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 35.0 bits (79), Expect = 1.4
Identities = 62/325 (19%), Positives = 133/325 (40%), Gaps = 39/325 (12%)
Query: 101 VKEEKSLQDVKQKELSRIEEALQKAAEKDKPKEAKKDTFV--EKLATQVIK---NVQVKI 155
V + ++Q + ++ R+E+A +K E + KEA +V EK + + K ++ K+
Sbjct: 277 VTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKL 336
Query: 156 TDIHIKYEDDVTDPKRPLSFGVTLGEL-SLLTANEHWTPCILNEADKIIYKLIRLDSLSA 214
D + + E + K+ G L L E T ++ E DK + + I +
Sbjct: 337 RDANKELEKNTNKIKQ---LSQEKGRLHQLYETKEGETTRLIREIDK-LKEDINSHVIKV 392
Query: 215 YWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKT 274
W N + S ++ D+LK I + K Y E+K+
Sbjct: 393 KWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQE---SEEIKS 449
Query: 275 PKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYA 334
+LD + + +E Q D LE + +A ++ + +R +K
Sbjct: 450 NELDAKLRVTKGELE---KQMQEKSDQLE-----MHHAKIKELEDL-------KRTFKEG 494
Query: 335 IDSV----LEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKVSEEIQ------- 383
+D + +V ++ + + K+++++ K +N L + K ++++Q
Sbjct: 495 MDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGK 554
Query: 384 KEIQDLEKTLDVFNIILARQQAQVE 408
+EI++L++ ++ N ++ Q +E
Sbjct: 555 QEIENLKEEVESLNSLINDLQKDIE 579
>gi|55749659 UHRF1 (ICBP90) binding protein 1-like isoform b [Homo
sapiens]
Length = 522
Score = 34.7 bits (78), Expect = 1.8
Identities = 34/192 (17%), Positives = 73/192 (38%), Gaps = 36/192 (18%)
Query: 3 LESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSE-LDVPFKVKAGQ 61
+ ++ + + L + +NL+ ++ L G L NL++ E L LD+P + +
Sbjct: 1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINK 60
Query: 62 I--DKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIE 119
+ +K +++IPW L + +L+ + + E+S E
Sbjct: 61 VFCNKASIRIPWTKLKTHPICLSLDKVIM-------------------------EMSTCE 95
Query: 120 EALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTL 179
E ++ P A +V++ + V + I I+ + + L
Sbjct: 96 E--PRSPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRI------GAKAFNASFEL 147
Query: 180 GELSLLTANEHW 191
+L + + N HW
Sbjct: 148 SQLRIYSVNAHW 159
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 126,737,896
Number of Sequences: 37866
Number of extensions: 5465083
Number of successful extensions: 16185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 15755
Number of HSP's gapped (non-prelim): 212
length of query: 3710
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3588
effective length of database: 13,627,866
effective search space: 48896783208
effective search space used: 48896783208
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.