Guide to the Human Genome
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Search of human proteins with 42476022

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens]
         (843 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens]        1687   0.0  
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]                     53   1e-06
gi|118402596 cell division cycle protein 23 [Homo sapiens]             49   2e-05
gi|118766328 transmembrane and tetratricopeptide repeat containi...    49   3e-05
gi|118766330 transmembrane and tetratricopeptide repeat containi...    49   3e-05
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]       47   6e-05
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]       47   6e-05
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi...    47   6e-05
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi...    47   6e-05
gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sap...    47   1e-04
gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sap...    47   1e-04
gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sap...    47   1e-04
gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sap...    47   1e-04
gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapi...    47   1e-04
gi|224809432 transmembrane and tetratricopeptide repeat containi...    46   1e-04
gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens]         46   2e-04
gi|83415184 transmembrane and tetratricopeptide repeat containin...    45   2e-04
gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho...    43   0.001
gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [H...    43   0.001
gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Ho...    43   0.001
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]           42   0.002
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ...    42   0.002
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-...    42   0.002
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ...    42   0.003
gi|124256489 crooked neck-like 1 protein [Homo sapiens]                41   0.004
gi|4503729 FK506 binding protein 52 [Homo sapiens]                     41   0.005
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]     40   0.009
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]         40   0.012
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]       40   0.012
gi|6912458 calcineurin binding protein 1 [Homo sapiens]                39   0.026

>gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens]
          Length = 843

 Score = 1687 bits (4368), Expect = 0.0
 Identities = 843/843 (100%), Positives = 843/843 (100%)

Query: 1   MWTPELAILRGFPTEAERQQWKQEGVVGSESGSFLQLLLEGNYEAIFLNSMTQNIFNSTT 60
           MWTPELAILRGFPTEAERQQWKQEGVVGSESGSFLQLLLEGNYEAIFLNSMTQNIFNSTT
Sbjct: 1   MWTPELAILRGFPTEAERQQWKQEGVVGSESGSFLQLLLEGNYEAIFLNSMTQNIFNSTT 60

Query: 61  TAEEKIDSYLEKQVVTFLDYSTDLDTTERQQLIFLLGVSSLQLFVQSNWTGPPVDLHPQD 120
           TAEEKIDSYLEKQVVTFLDYSTDLDTTERQQLIFLLGVSSLQLFVQSNWTGPPVDLHPQD
Sbjct: 61  TAEEKIDSYLEKQVVTFLDYSTDLDTTERQQLIFLLGVSSLQLFVQSNWTGPPVDLHPQD 120

Query: 121 FLSSVLFQQFSEVKGLDAFVLSLLTLDGESIYSLTSKPILLLLARIILVNVRHKLTAIQS 180
           FLSSVLFQQFSEVKGLDAFVLSLLTLDGESIYSLTSKPILLLLARIILVNVRHKLTAIQS
Sbjct: 121 FLSSVLFQQFSEVKGLDAFVLSLLTLDGESIYSLTSKPILLLLARIILVNVRHKLTAIQS 180

Query: 181 LPWWTLRCVNIHQHLLEERSPLLFTLAENCIDQVMKLQNLFVDDSGRYLAIQFHLECAYV 240
           LPWWTLRCVNIHQHLLEERSPLLFTLAENCIDQVMKLQNLFVDDSGRYLAIQFHLECAYV
Sbjct: 181 LPWWTLRCVNIHQHLLEERSPLLFTLAENCIDQVMKLQNLFVDDSGRYLAIQFHLECAYV 240

Query: 241 FLYYYEYRKAKDQLDIAKDISQLQIDLTGALGKRTRFQENYVAQLILDVRREGDVLSNCE 300
           FLYYYEYRKAKDQLDIAKDISQLQIDLTGALGKRTRFQENYVAQLILDVRREGDVLSNCE
Sbjct: 241 FLYYYEYRKAKDQLDIAKDISQLQIDLTGALGKRTRFQENYVAQLILDVRREGDVLSNCE 300

Query: 301 FTPAPTPQEHLTKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPV 360
           FTPAPTPQEHLTKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPV
Sbjct: 301 FTPAPTPQEHLTKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPV 360

Query: 361 HTLTEVELLAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDK 420
           HTLTEVELLAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDK
Sbjct: 361 HTLTEVELLAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDK 420

Query: 421 TTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAG 480
           TTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAG
Sbjct: 421 TTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAG 480

Query: 481 QHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRN 540
           QHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRN
Sbjct: 481 QHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRN 540

Query: 541 KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNN 600
           KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNN
Sbjct: 541 KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNN 600

Query: 601 LSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRD 660
           LSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRD
Sbjct: 601 LSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRD 660

Query: 661 KYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYG 720
           KYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYG
Sbjct: 661 KYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYG 720

Query: 721 NGQSEKPDENEKAFQCLSKAYKCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSS 780
           NGQSEKPDENEKAFQCLSKAYKCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSS
Sbjct: 721 NGQSEKPDENEKAFQCLSKAYKCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSS 780

Query: 781 SQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFR 840
           SQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFR
Sbjct: 781 SQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFR 840

Query: 841 NQY 843
           NQY
Sbjct: 841 NQY 843


>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
          Length = 519

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 53/262 (20%), Positives = 105/262 (40%), Gaps = 16/262 (6%)

Query: 423 SVLERLKIFYCCQV--PPHWAIQRQLASLLFELGCTSSALQIFEKLEM-----WE---DV 472
           ++ E L++F  C V  P      +Q+A  LF LG   +A++++ +        WE   ++
Sbjct: 82  NIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNL 141

Query: 473 VICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRY------RS 526
            +CY    Q  KA++ L   L        Y +LG +       DKA E+ +        +
Sbjct: 142 GVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPEN 201

Query: 527 ARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQR 586
                +  LL+L+   +Q+  E    ++  +P       + G       D+  +   ++ 
Sbjct: 202 TELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRV 261

Query: 587 CVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFS 646
                P++   WNN+   +   K+ V A   L+ A       W+I  N  L    + +++
Sbjct: 262 VACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYA 321

Query: 647 EAIKAYHRLLDLRDKYKDVQVL 668
            A       ++ + K  ++ +L
Sbjct: 322 SAFHFLSAAINFQPKMGELYML 343



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 41/201 (20%), Positives = 80/201 (39%), Gaps = 11/201 (5%)

Query: 464 EKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLL-GDVLGDHSCYDKAWELS 522
           E  E+   + + Y + G + KA E L   L    T     L  G ++  H  +D A  L+
Sbjct: 200 ENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVA--LT 257

Query: 523 RYR--------SARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLAL 574
           +YR        S     +  +     K++   + C +R+  + P    + ++LG  +L +
Sbjct: 258 KYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTM 317

Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWEN 634
           + Y  +       +  +P   E +  L+ +   L+    A R   EA+  +  +  +  N
Sbjct: 318 QQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLN 377

Query: 635 YILTSTDVGEFSEAIKAYHRL 655
           Y +   + GE   A+  Y  +
Sbjct: 378 YAVLLYNQGEKKNALAQYQEM 398



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 29/124 (23%), Positives = 51/124 (41%), Gaps = 1/124 (0%)

Query: 536 LHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALE-DYQGSAKAFQRCVTLEPDN 594
           LH   K+++ C    +  ++           +      LE + Q S + FQ C  L P +
Sbjct: 41  LHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQS 100

Query: 595 AEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHR 654
           A+    ++ S   L +   A     EA K N + W+I  N  +    + +F++A    H 
Sbjct: 101 ADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHN 160

Query: 655 LLDL 658
            L+L
Sbjct: 161 ALNL 164



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 28/128 (21%), Positives = 54/128 (42%), Gaps = 7/128 (5%)

Query: 533 KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEP 592
           +AL+       QE +E F+    ++P        +  +   L  ++ + + +     L  
Sbjct: 73  QALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQ 132

Query: 593 DNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN---YEHWQIWENYILTSTDVGEFSEAI 649
            + E  +NL   YI LKQ  KA   L  AL  N     +  + + ++L     G+  +AI
Sbjct: 133 KDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLE----GDLDKAI 188

Query: 650 KAYHRLLD 657
           + Y + ++
Sbjct: 189 EVYKKAVE 196


>gi|118402596 cell division cycle protein 23 [Homo sapiens]
          Length = 597

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 53/247 (21%), Positives = 98/247 (39%), Gaps = 46/247 (18%)

Query: 363 LTEVELLAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDKTT 422
           +T+ E+L F    LS P  W  +     + T+L+      +E A+++ Q L D    K++
Sbjct: 213 ITDKEMLKF----LSLPDTWMKEFFLAHIYTELQL-----IEEALQKYQNLIDVGFSKSS 263

Query: 423 SVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAGQH 482
            ++ ++ + Y                    +     AL IF +L   +       R    
Sbjct: 264 YIVSQIAVAY------------------HNIRDIDKALSIFNELRKQDPY-----RIENM 300

Query: 483 GKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKE 542
                +L     K E   L   L ++  D    +    +  Y S R+Q  KA L+     
Sbjct: 301 DTFSNLLYVRSMKSELSYLAHNLCEI--DKYRVETCCVIGNYYSLRSQHEKAALY----- 353

Query: 543 FQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLS 602
                  F+R++K+NP  LG W  +G  Y+ +++   + +A++  + +   +  AW  L 
Sbjct: 354 -------FQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLG 406

Query: 603 TSYIRLK 609
            +Y  LK
Sbjct: 407 QTYEILK 413



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 24/120 (20%), Positives = 50/120 (41%), Gaps = 1/120 (0%)

Query: 513 SCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYL 572
           S +++  +   YR         LL++R+ +  E         +I+  ++     +G  Y 
Sbjct: 284 SIFNELRKQDPYRIENMDTFSNLLYVRSMK-SELSYLAHNLCEIDKYRVETCCVIGNYYS 342

Query: 573 ALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIW 632
               ++ +A  FQR + L P    AW  +   Y+ +K    A +  + A++ N   ++ W
Sbjct: 343 LRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAW 402


>gi|118766328 transmembrane and tetratricopeptide repeat containing
           4 isoform 2 [Homo sapiens]
          Length = 741

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 42/193 (21%), Positives = 74/193 (38%), Gaps = 11/193 (5%)

Query: 475 CYERAGQHGKAEEILRQELEKKE-TPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSK 533
           C  R+G+    E++ R  L        ++  +G  L D      A  +  YR A     K
Sbjct: 457 CVLRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAA--IRYYREAVRLNPK 514

Query: 534 ALLHLRN--------KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQ 585
            +  + N         E QE  E    +V+I P     W +LG    +L+ ++ + ++++
Sbjct: 515 YVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYR 574

Query: 586 RCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEF 645
             +       + + NL   Y  L + V A    + A     EH   W N I+   + G  
Sbjct: 575 TAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNL 634

Query: 646 SEAIKAYHRLLDL 658
           ++A       L+L
Sbjct: 635 AQAEAVGREALEL 647



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 39/184 (21%), Positives = 74/184 (40%), Gaps = 14/184 (7%)

Query: 547 VECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYI 606
           +  +  +V++NP  +    +LG       + Q + +     V ++PD A AW NL     
Sbjct: 502 IRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQN 561

Query: 607 RLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQ 666
            LK+   A ++ + A+K   ++   + N      D+    +A+ A+     L+ ++    
Sbjct: 562 SLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAW 621

Query: 667 VLKILVRAVIDGMTDRSGDVATGLKGKLQELFGR-VTSRVTNDGEIWRLYAHVYGNGQSE 725
              I+       + D +G++A        E  GR     + ND  +    A+V G  Q  
Sbjct: 622 NNMII-------LLDNTGNLAQA------EAVGREALELIPNDHSLMFSLANVLGKSQKY 668

Query: 726 KPDE 729
           K  E
Sbjct: 669 KESE 672



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 26/127 (20%), Positives = 52/127 (40%)

Query: 538 LRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEA 597
           LR+ E++   + F  ++ + P+   V +++G       +   + + ++  V L P    A
Sbjct: 459 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHA 518

Query: 598 WNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLD 657
            NNL        +  +A   L  A++   +    W N  +    +  F  A ++Y   + 
Sbjct: 519 MNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIK 578

Query: 658 LRDKYKD 664
            R KY D
Sbjct: 579 HRRKYPD 585


>gi|118766330 transmembrane and tetratricopeptide repeat containing
           4 isoform 1 [Homo sapiens]
          Length = 760

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 42/193 (21%), Positives = 74/193 (38%), Gaps = 11/193 (5%)

Query: 475 CYERAGQHGKAEEILRQELEKKE-TPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSK 533
           C  R+G+    E++ R  L        ++  +G  L D      A  +  YR A     K
Sbjct: 476 CVLRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAA--IRYYREAVRLNPK 533

Query: 534 ALLHLRN--------KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQ 585
            +  + N         E QE  E    +V+I P     W +LG    +L+ ++ + ++++
Sbjct: 534 YVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYR 593

Query: 586 RCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEF 645
             +       + + NL   Y  L + V A    + A     EH   W N I+   + G  
Sbjct: 594 TAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNL 653

Query: 646 SEAIKAYHRLLDL 658
           ++A       L+L
Sbjct: 654 AQAEAVGREALEL 666



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 39/184 (21%), Positives = 74/184 (40%), Gaps = 14/184 (7%)

Query: 547 VECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYI 606
           +  +  +V++NP  +    +LG       + Q + +     V ++PD A AW NL     
Sbjct: 521 IRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQN 580

Query: 607 RLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQ 666
            LK+   A ++ + A+K   ++   + N      D+    +A+ A+     L+ ++    
Sbjct: 581 SLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAW 640

Query: 667 VLKILVRAVIDGMTDRSGDVATGLKGKLQELFGR-VTSRVTNDGEIWRLYAHVYGNGQSE 725
              I+       + D +G++A        E  GR     + ND  +    A+V G  Q  
Sbjct: 641 NNMII-------LLDNTGNLAQA------EAVGREALELIPNDHSLMFSLANVLGKSQKY 687

Query: 726 KPDE 729
           K  E
Sbjct: 688 KESE 691



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 26/127 (20%), Positives = 52/127 (40%)

Query: 538 LRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEA 597
           LR+ E++   + F  ++ + P+   V +++G       +   + + ++  V L P    A
Sbjct: 478 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHA 537

Query: 598 WNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLD 657
            NNL        +  +A   L  A++   +    W N  +    +  F  A ++Y   + 
Sbjct: 538 MNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIK 597

Query: 658 LRDKYKD 664
            R KY D
Sbjct: 598 HRRKYPD 604


>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
          Length = 1036

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 49/210 (23%), Positives = 82/210 (39%), Gaps = 17/210 (8%)

Query: 467 EMWEDVVICYERAGQHGKAEEILRQELEKK--------ETPSLYCLLGDVLGDHSCYDKA 518
           E + ++   Y+  GQ  +A E  R  L  K           +     GD+ G    Y  A
Sbjct: 80  EAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 139

Query: 519 WE----LSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLAL 574
            +    L   RS      KAL  L     +E   C+ ++++  P     W +LGC + A 
Sbjct: 140 LQYNPDLYCVRSDLGNLLKALGRL-----EEAKACYLKAIETQPNFAVAWSNLGCVFNAQ 194

Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWEN 634
            +   +   F++ VTL+P+  +A+ NL       +   +A      AL  +  H  +  N
Sbjct: 195 GEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGN 254

Query: 635 YILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664
                 + G    AI  Y R ++L+  + D
Sbjct: 255 LACVYYEQGLIDLAIDTYRRAIELQPHFPD 284



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 11/176 (6%)

Query: 499 PSLYCLLGDV------LGD----HSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVE 548
           P LYC+  D+      LG      +CY KA E ++   A A  +   +     E    + 
Sbjct: 144 PDLYCVRSDLGNLLKALGRLEEAKACYLKAIE-TQPNFAVAWSNLGCVFNAQGEIWLAIH 202

Query: 549 CFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRL 608
            FE++V ++P  L  + +LG        +  +  A+ R ++L P++A    NL+  Y   
Sbjct: 203 HFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQ 262

Query: 609 KQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664
                A  T + A++        + N      + G  +EA   Y+  L L   + D
Sbjct: 263 GLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHAD 318



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 28/123 (22%), Positives = 58/123 (47%), Gaps = 10/123 (8%)

Query: 515 YDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLAL 574
           Y KA E+    +A      ++L  + K  QE +  ++ +++I+P     + ++G     +
Sbjct: 340 YRKALEVFPEFAAAHSNLASVLQQQGK-LQEALMHYKEAIRISPTFADAYSNMGNTLKEM 398

Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK---------CN 625
           +D QG+ + + R + + P  A+A +NL++ +       +A  + + ALK         CN
Sbjct: 399 QDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCN 458

Query: 626 YEH 628
             H
Sbjct: 459 LAH 461



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 24/116 (20%), Positives = 47/116 (40%)

Query: 543 FQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLS 602
           F   V  + R++ ++P    V  +L C Y        +   ++R + L+P   +A+ NL+
Sbjct: 231 FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLA 290

Query: 603 TSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDL 658
            +        +A      AL+    H     N      + G   EA++ Y + L++
Sbjct: 291 NALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 346



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 21/127 (16%), Positives = 52/127 (40%)

Query: 536 LHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNA 595
           +H + +           ++K NP+    + +LG  Y      Q + + ++  + L+PD  
Sbjct: 54  IHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFI 113

Query: 596 EAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRL 655
           + + NL+ + +       A +    AL+ N + + +  +       +G   EA   Y + 
Sbjct: 114 DGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKA 173

Query: 656 LDLRDKY 662
           ++ +  +
Sbjct: 174 IETQPNF 180



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 5/104 (4%)

Query: 566 SLGCAYLALEDYQ-GSAKAFQR-CVTL---EPDNAEAWNNLSTSYIRLKQKVKAFRTLQE 620
           S G A LA  +YQ G  +A +R C+ L   EPDN      LS+ + + ++  ++      
Sbjct: 11  STGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTL 70

Query: 621 ALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664
           A+K N    + + N      + G+  EAI+ Y   L L+  + D
Sbjct: 71  AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFID 114


>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
          Length = 1046

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 49/210 (23%), Positives = 82/210 (39%), Gaps = 17/210 (8%)

Query: 467 EMWEDVVICYERAGQHGKAEEILRQELEKK--------ETPSLYCLLGDVLGDHSCYDKA 518
           E + ++   Y+  GQ  +A E  R  L  K           +     GD+ G    Y  A
Sbjct: 90  EAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 149

Query: 519 WE----LSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLAL 574
            +    L   RS      KAL  L     +E   C+ ++++  P     W +LGC + A 
Sbjct: 150 LQYNPDLYCVRSDLGNLLKALGRL-----EEAKACYLKAIETQPNFAVAWSNLGCVFNAQ 204

Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWEN 634
            +   +   F++ VTL+P+  +A+ NL       +   +A      AL  +  H  +  N
Sbjct: 205 GEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGN 264

Query: 635 YILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664
                 + G    AI  Y R ++L+  + D
Sbjct: 265 LACVYYEQGLIDLAIDTYRRAIELQPHFPD 294



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 11/176 (6%)

Query: 499 PSLYCLLGDV------LGD----HSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVE 548
           P LYC+  D+      LG      +CY KA E ++   A A  +   +     E    + 
Sbjct: 154 PDLYCVRSDLGNLLKALGRLEEAKACYLKAIE-TQPNFAVAWSNLGCVFNAQGEIWLAIH 212

Query: 549 CFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRL 608
            FE++V ++P  L  + +LG        +  +  A+ R ++L P++A    NL+  Y   
Sbjct: 213 HFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQ 272

Query: 609 KQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664
                A  T + A++        + N      + G  +EA   Y+  L L   + D
Sbjct: 273 GLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHAD 328



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 28/123 (22%), Positives = 58/123 (47%), Gaps = 10/123 (8%)

Query: 515 YDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLAL 574
           Y KA E+    +A      ++L  + K  QE +  ++ +++I+P     + ++G     +
Sbjct: 350 YRKALEVFPEFAAAHSNLASVLQQQGK-LQEALMHYKEAIRISPTFADAYSNMGNTLKEM 408

Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK---------CN 625
           +D QG+ + + R + + P  A+A +NL++ +       +A  + + ALK         CN
Sbjct: 409 QDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCN 468

Query: 626 YEH 628
             H
Sbjct: 469 LAH 471



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 24/116 (20%), Positives = 47/116 (40%)

Query: 543 FQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLS 602
           F   V  + R++ ++P    V  +L C Y        +   ++R + L+P   +A+ NL+
Sbjct: 241 FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLA 300

Query: 603 TSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDL 658
            +        +A      AL+    H     N      + G   EA++ Y + L++
Sbjct: 301 NALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 356



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 21/127 (16%), Positives = 52/127 (40%)

Query: 536 LHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNA 595
           +H + +           ++K NP+    + +LG  Y      Q + + ++  + L+PD  
Sbjct: 64  IHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFI 123

Query: 596 EAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRL 655
           + + NL+ + +       A +    AL+ N + + +  +       +G   EA   Y + 
Sbjct: 124 DGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKA 183

Query: 656 LDLRDKY 662
           ++ +  +
Sbjct: 184 IETQPNF 190



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 5/102 (4%)

Query: 568 GCAYLALEDYQ-GSAKAFQR-CVTL---EPDNAEAWNNLSTSYIRLKQKVKAFRTLQEAL 622
           G A LA  +YQ G  +A +R C+ L   EPDN      LS+ + + ++  ++      A+
Sbjct: 23  GLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAI 82

Query: 623 KCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664
           K N    + + N      + G+  EAI+ Y   L L+  + D
Sbjct: 83  KQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFID 124


>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
           sapiens]
          Length = 830

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 40/194 (20%), Positives = 82/194 (42%), Gaps = 17/194 (8%)

Query: 445 QLASLLFELGCTSSALQIFEKLEMWEDVVI----CYERAGQHGKAE---EILRQELEK-- 495
           Q+    FEL     A +IF ++   E+  +     Y     H + +    +L ++L    
Sbjct: 510 QIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMD 569

Query: 496 KETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLH-------LRNKEFQECVE 548
           K +P  +C  G+       +D A +  + R+ +   + A  +       +  +E  + + 
Sbjct: 570 KNSPEAWCAAGNCFSLQREHDIAIKFFQ-RAIQVDPNYAYAYTLLGHEFVLTEELDKALA 628

Query: 549 CFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRL 608
           CF  ++++NP     W+ LG  Y   E +  +   FQ+ + + P ++    ++      L
Sbjct: 629 CFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHAL 688

Query: 609 KQKVKAFRTLQEAL 622
           K+  KA  TL +A+
Sbjct: 689 KKSEKALDTLNKAI 702



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 21/95 (22%), Positives = 44/95 (46%)

Query: 564 WFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK 623
           W + G  +    ++  + K FQR + ++P+ A A+  L   ++  ++  KA    + A++
Sbjct: 576 WCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR 635

Query: 624 CNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDL 658
            N  H+  W    +      +FS A   + + LD+
Sbjct: 636 VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDI 670



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 24/121 (19%), Positives = 52/121 (42%), Gaps = 7/121 (5%)

Query: 541 KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNN 600
           +E    ++ F+R+++++P     +  LG  ++  E+   +   F+  + + P +  AW  
Sbjct: 587 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 646

Query: 601 LSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRD 660
           L   Y + ++   A    Q+AL  N +         +    +G    A+K   + LD  +
Sbjct: 647 LGMIYYKQEKFSLAEMHFQKALDINPQS-------SVLLCHIGVVQHALKKSEKALDTLN 699

Query: 661 K 661
           K
Sbjct: 700 K 700


>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
           sapiens]
          Length = 824

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 40/194 (20%), Positives = 82/194 (42%), Gaps = 17/194 (8%)

Query: 445 QLASLLFELGCTSSALQIFEKLEMWEDVVI----CYERAGQHGKAE---EILRQELEK-- 495
           Q+    FEL     A +IF ++   E+  +     Y     H + +    +L ++L    
Sbjct: 504 QIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMD 563

Query: 496 KETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLH-------LRNKEFQECVE 548
           K +P  +C  G+       +D A +  + R+ +   + A  +       +  +E  + + 
Sbjct: 564 KNSPEAWCAAGNCFSLQREHDIAIKFFQ-RAIQVDPNYAYAYTLLGHEFVLTEELDKALA 622

Query: 549 CFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRL 608
           CF  ++++NP     W+ LG  Y   E +  +   FQ+ + + P ++    ++      L
Sbjct: 623 CFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHAL 682

Query: 609 KQKVKAFRTLQEAL 622
           K+  KA  TL +A+
Sbjct: 683 KKSEKALDTLNKAI 696



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 21/95 (22%), Positives = 44/95 (46%)

Query: 564 WFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK 623
           W + G  +    ++  + K FQR + ++P+ A A+  L   ++  ++  KA    + A++
Sbjct: 570 WCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR 629

Query: 624 CNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDL 658
            N  H+  W    +      +FS A   + + LD+
Sbjct: 630 VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDI 664



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 24/121 (19%), Positives = 52/121 (42%), Gaps = 7/121 (5%)

Query: 541 KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNN 600
           +E    ++ F+R+++++P     +  LG  ++  E+   +   F+  + + P +  AW  
Sbjct: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640

Query: 601 LSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRD 660
           L   Y + ++   A    Q+AL  N +         +    +G    A+K   + LD  +
Sbjct: 641 LGMIYYKQEKFSLAEMHFQKALDINPQS-------SVLLCHIGVVQHALKKSEKALDTLN 693

Query: 661 K 661
           K
Sbjct: 694 K 694


>gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo
           sapiens]
          Length = 639

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571
           YDK ++       R       + L  L+  +    V  FE +V+ +P  +  W  LG   
Sbjct: 320 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 379

Query: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629
              E    +  A +RC+ L+PDN  A   L+ S+     + +A  TL++ L+    Y H 
Sbjct: 380 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 438

Query: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688
                 ++T  + G     +    R+L  L      ++V ++ + AV    T    DV  
Sbjct: 439 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 492

Query: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726
           GL G L  L G     V           ND  +W        NG QSE+
Sbjct: 493 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 21/81 (25%), Positives = 36/81 (44%)

Query: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601
           E+ + V+CF  ++ + P    +W  LG         + +  A++R + L+P    +  NL
Sbjct: 503 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 562

Query: 602 STSYIRLKQKVKAFRTLQEAL 622
             S I L    +A     EAL
Sbjct: 563 GISCINLGAHREAVEHFLEAL 583


>gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo
           sapiens]
          Length = 639

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571
           YDK ++       R       + L  L+  +    V  FE +V+ +P  +  W  LG   
Sbjct: 320 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 379

Query: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629
              E    +  A +RC+ L+PDN  A   L+ S+     + +A  TL++ L+    Y H 
Sbjct: 380 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 438

Query: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688
                 ++T  + G     +    R+L  L      ++V ++ + AV    T    DV  
Sbjct: 439 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 492

Query: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726
           GL G L  L G     V           ND  +W        NG QSE+
Sbjct: 493 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 21/81 (25%), Positives = 36/81 (44%)

Query: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601
           E+ + V+CF  ++ + P    +W  LG         + +  A++R + L+P    +  NL
Sbjct: 503 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 562

Query: 602 STSYIRLKQKVKAFRTLQEAL 622
             S I L    +A     EAL
Sbjct: 563 GISCINLGAHREAVEHFLEAL 583


>gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo
           sapiens]
          Length = 602

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571
           YDK ++       R       + L  L+  +    V  FE +V+ +P  +  W  LG   
Sbjct: 283 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 342

Query: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629
              E    +  A +RC+ L+PDN  A   L+ S+     + +A  TL++ L+    Y H 
Sbjct: 343 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 401

Query: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688
                 ++T  + G     +    R+L  L      ++V ++ + AV    T    DV  
Sbjct: 402 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 455

Query: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726
           GL G L  L G     V           ND  +W        NG QSE+
Sbjct: 456 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 503



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 21/81 (25%), Positives = 36/81 (44%)

Query: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601
           E+ + V+CF  ++ + P    +W  LG         + +  A++R + L+P    +  NL
Sbjct: 466 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 525

Query: 602 STSYIRLKQKVKAFRTLQEAL 622
             S I L    +A     EAL
Sbjct: 526 GISCINLGAHREAVEHFLEAL 546


>gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo
           sapiens]
          Length = 654

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571
           YDK ++       R       + L  L+  +    V  FE +V+ +P  +  W  LG   
Sbjct: 335 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 394

Query: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629
              E    +  A +RC+ L+PDN  A   L+ S+     + +A  TL++ L+    Y H 
Sbjct: 395 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 453

Query: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688
                 ++T  + G     +    R+L  L      ++V ++ + AV    T    DV  
Sbjct: 454 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 507

Query: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726
           GL G L  L G     V           ND  +W        NG QSE+
Sbjct: 508 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 555



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 21/81 (25%), Positives = 36/81 (44%)

Query: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601
           E+ + V+CF  ++ + P    +W  LG         + +  A++R + L+P    +  NL
Sbjct: 518 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 577

Query: 602 STSYIRLKQKVKAFRTLQEAL 622
             S I L    +A     EAL
Sbjct: 578 GISCINLGAHREAVEHFLEAL 598


>gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo
           sapiens]
          Length = 631

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%)

Query: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571
           YDK ++       R       + L  L+  +    V  FE +V+ +P  +  W  LG   
Sbjct: 312 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 371

Query: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629
              E    +  A +RC+ L+PDN  A   L+ S+     + +A  TL++ L+    Y H 
Sbjct: 372 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 430

Query: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688
                 ++T  + G     +    R+L  L      ++V ++ + AV    T    DV  
Sbjct: 431 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 484

Query: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726
           GL G L  L G     V           ND  +W        NG QSE+
Sbjct: 485 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 532



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 21/81 (25%), Positives = 36/81 (44%)

Query: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601
           E+ + V+CF  ++ + P    +W  LG         + +  A++R + L+P    +  NL
Sbjct: 495 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 554

Query: 602 STSYIRLKQKVKAFRTLQEAL 622
             S I L    +A     EAL
Sbjct: 555 GISCINLGAHREAVEHFLEAL 575


>gi|224809432 transmembrane and tetratricopeptide repeat containing
           3 [Homo sapiens]
          Length = 914

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 28/122 (22%), Positives = 56/122 (45%)

Query: 535 LLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDN 594
           L+       +E  + + +++ + P     + S G   L +     + +A+ + + L+ +N
Sbjct: 537 LIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNN 596

Query: 595 AEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHR 654
           A+ W NL+  +I LK+  +A +    AL+ N +H     N  +   + GE     +A  R
Sbjct: 597 ADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKR 656

Query: 655 LL 656
           LL
Sbjct: 657 LL 658



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 26/112 (23%), Positives = 59/112 (52%), Gaps = 1/112 (0%)

Query: 553 SVKINPMQLGVWFSLGCAYLALEDYQGSA-KAFQRCVTLEPDNAEAWNNLSTSYIRLKQK 611
           + +I P  L V+ +L     A E     A + +++ +++ PD  +A+ +     +++ + 
Sbjct: 520 AARIAPNHLNVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKP 579

Query: 612 VKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYK 663
           +KA     +AL+ +  +  +W N  +   ++ E +EA+K ++R L+L  K+K
Sbjct: 580 LKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHK 631



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQE--ALKCNYEHWQIW 632
           +D  G+ K F+R + ++P N +  +NL   Y   K  +KA R L E  AL  + E+ Q  
Sbjct: 751 KDILGAKKCFERILEMDPSNVQGKHNLCVVYFEEKDLLKAERCLLETLALAPHEEYIQRH 810

Query: 633 ENYILTSTDVGEFSEAI 649
            N +        F E I
Sbjct: 811 LNIVRDKISSSSFIEPI 827



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 26/144 (18%), Positives = 60/144 (41%), Gaps = 15/144 (10%)

Query: 539 RNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAW 598
           RN +++     F  ++K+N     +W ++G A    ++++ + K F +   ++PD+  A 
Sbjct: 424 RNWDWESEYTLFMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGAH 483

Query: 599 NNLSTSYIRLKQKVKAFRTL--------------QEALKCNYEHWQIWENYI-LTSTDVG 643
            N+  +Y  L +  +A  +               + A +    H  ++ N   L   +  
Sbjct: 484 MNVGRTYKNLNRTKEAEESYMMAKSLMPQIIPGKKYAARIAPNHLNVYINLANLIRANES 543

Query: 644 EFSEAIKAYHRLLDLRDKYKDVQV 667
              EA + Y + + +R  +K   +
Sbjct: 544 RLEEADQLYRQAISMRPDFKQAYI 567



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 34/153 (22%), Positives = 64/153 (41%), Gaps = 42/153 (27%)

Query: 515 YDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKIN----------------- 557
           Y KA EL R  +A    + A++H+  KE  E ++ F R++++N                 
Sbjct: 586 YLKALELDR-NNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAIVMQES 644

Query: 558 --------------------PMQLGVWFSLGCAYLALEDYQGSAKA--FQRCVTLEPDNA 595
                               P+    +F+LG   LA++D + +      ++ + L+ D  
Sbjct: 645 GEVKLRPEARKRLLSYINEEPLDANGYFNLG--MLAMDDKKDNEAEIWMKKAIKLQADFR 702

Query: 596 EAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEH 628
            A  NL+  Y +  +++KA   L+E L+   +H
Sbjct: 703 SALFNLALLYSQTAKELKALPILEELLRYYPDH 735


>gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens]
          Length = 1121

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 6/139 (4%)

Query: 533  KALLHLRNKEFQECVECFERSVK--INPMQLG-VWFSLGCAYLALEDYQGSAKAFQRCVT 589
            K  L+  +    E   C+ER++   ++  ++  ++  LG  YL  ++Y+ + K + +   
Sbjct: 969  KGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACK 1028

Query: 590  LEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAI 649
              P +   W  L  +  RL++  +A   L EA   N  + ++W    L    VG   EA 
Sbjct: 1029 RSP-SCLTWLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAE 1087

Query: 650  KAYHRLLDLRDKYKDVQVL 668
            +AY  ++ L  K KD  +L
Sbjct: 1088 QAYKYMIKL--KLKDEALL 1104



 Score = 37.7 bits (86), Expect = 0.045
 Identities = 20/76 (26%), Positives = 33/76 (43%)

Query: 548 ECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIR 607
           ECF++++ +N   +      G   + LE+Y+ +   F+    LEP N  AW  L   Y  
Sbjct: 690 ECFQKALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEI 749

Query: 608 LKQKVKAFRTLQEALK 623
               ++      EA K
Sbjct: 750 QNNDIRMEMAFHEASK 765


>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
           [Homo sapiens]
          Length = 774

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 65/337 (19%), Positives = 135/337 (40%), Gaps = 37/337 (10%)

Query: 530 QRSKALLHLRN-----KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAF 584
           Q ++AL +L N     ++ +E +   + S+K  P     + SL       E ++ + + +
Sbjct: 438 QHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIY 497

Query: 585 QRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGE 644
           Q  +   PD+++  NN     +      KA    Q+A+K +  H     N       +GE
Sbjct: 498 QTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGE 557

Query: 645 FSEAIKAYHRLLDLRDKYKDV--------------QVLKILVRAVIDGMTDRSGDVA--- 687
            S A + Y R L +  K + +              + L+I   A     + R   +A   
Sbjct: 558 NSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQ 617

Query: 688 ----TGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYGNGQSEKP--DENEKAFQCLSKAY 741
                G   + +++   + S  T   E +RL + +Y   ++     D  +KA Q   K  
Sbjct: 618 VLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDP 677

Query: 742 KCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSS---SQEAVQMLSSVRLNLRGL 798
           K  ++    + +    + ++ +A     VA++ + +++    +   +Q +    ++ R  
Sbjct: 678 KVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAY 737

Query: 799 LSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDL 835
             +A QL  D      S+ L +++  +D L   LQ++
Sbjct: 738 YERALQLVPD------SKLLKENLAKLDRLEKRLQEV 768



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 20/109 (18%), Positives = 51/109 (46%)

Query: 550 FERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLK 609
           ++R+++++P      F+LG    + E  + +    +  +   P+ A+A+++L++     +
Sbjct: 429 YQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQE 488

Query: 610 QKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDL 658
           +  +A    Q  +K   +   +  NY +   D G   +A+  Y + + L
Sbjct: 489 RFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKL 537


>gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo
           sapiens]
          Length = 864

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 27/217 (12%)

Query: 535 LLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDN 594
           LL   +K++ E ++C+  ++K++   L +   L    + + D +G  +   + + L P  
Sbjct: 88  LLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQ 147

Query: 595 AEAWNNLSTSYIRLKQKVKAFRTLQE--------ALKCNYEHWQ--IWENYILTSTDVGE 644
             +W   + +Y  LK    A + L+E          K +YE+ +  +++N ++   D+ +
Sbjct: 148 RASWIGYAIAYHLLKDYDMALKLLEEFRQTQQVPPNKIDYEYSELILYQNQVMREADLLQ 207

Query: 645 FSEAIKAYHRLLDLRDKYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSR 704
            S         L+  + Y+     K+LV  +        G++   L G+L+E      + 
Sbjct: 208 ES---------LEHIEMYEKQICDKLLVEEI-------KGEILLKL-GRLKEASEVFKNL 250

Query: 705 VTNDGEIWRLYAHVYGNGQSEKPDENEKAFQCLSKAY 741
           +  + E W  Y  +    Q    +E  + ++ +SK +
Sbjct: 251 IDRNAENWCYYEGLEKALQISTLEERLQIYEEISKQH 287



 Score = 33.9 bits (76), Expect = 0.65
 Identities = 35/156 (22%), Positives = 69/156 (44%), Gaps = 11/156 (7%)

Query: 514 CYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLA 573
           CY  A +L +  + +  R  +LL ++ ++ +   E   + +++ P Q   W     AY  
Sbjct: 102 CYRNALKLDK-DNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHL 160

Query: 574 LEDYQGSAK---AFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQ 630
           L+DY  + K    F++   + P+  +     S   +   Q ++    LQE+L    EH +
Sbjct: 161 LKDYDMALKLLEEFRQTQQVPPNKID--YEYSELILYQNQVMREADLLQESL----EHIE 214

Query: 631 IWENYILTSTDVGEF-SEAIKAYHRLLDLRDKYKDV 665
           ++E  I     V E   E +    RL +  + +K++
Sbjct: 215 MYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNL 250


>gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [Homo
           sapiens]
          Length = 429

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 27/217 (12%)

Query: 535 LLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDN 594
           LL   +K++ E ++C+  ++K++   L +   L    + + D +G  +   + + L P  
Sbjct: 88  LLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQ 147

Query: 595 AEAWNNLSTSYIRLKQKVKAFRTLQE--------ALKCNYEHWQ--IWENYILTSTDVGE 644
             +W   + +Y  LK    A + L+E          K +YE+ +  +++N ++   D+ +
Sbjct: 148 RASWIGYAIAYHLLKDYDMALKLLEEFRQTQQVPPNKIDYEYSELILYQNQVMREADLLQ 207

Query: 645 FSEAIKAYHRLLDLRDKYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSR 704
            S         L+  + Y+     K+LV  +        G++   L G+L+E      + 
Sbjct: 208 ES---------LEHIEMYEKQICDKLLVEEI-------KGEILLKL-GRLKEASEVFKNL 250

Query: 705 VTNDGEIWRLYAHVYGNGQSEKPDENEKAFQCLSKAY 741
           +  + E W  Y  +    Q    +E  + ++ +SK +
Sbjct: 251 IDRNAENWCYYEGLEKALQISTLEERLQIYEEISKQH 287



 Score = 33.9 bits (76), Expect = 0.65
 Identities = 35/156 (22%), Positives = 69/156 (44%), Gaps = 11/156 (7%)

Query: 514 CYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLA 573
           CY  A +L +  + +  R  +LL ++ ++ +   E   + +++ P Q   W     AY  
Sbjct: 102 CYRNALKLDK-DNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHL 160

Query: 574 LEDYQGSAK---AFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQ 630
           L+DY  + K    F++   + P+  +     S   +   Q ++    LQE+L    EH +
Sbjct: 161 LKDYDMALKLLEEFRQTQQVPPNKID--YEYSELILYQNQVMREADLLQESL----EHIE 214

Query: 631 IWENYILTSTDVGEF-SEAIKAYHRLLDLRDKYKDV 665
           ++E  I     V E   E +    RL +  + +K++
Sbjct: 215 MYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNL 250


>gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Homo
           sapiens]
          Length = 311

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 27/217 (12%)

Query: 535 LLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDN 594
           LL   +K++ E ++C+  ++K++   L +   L    + + D +G  +   + + L P  
Sbjct: 88  LLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQ 147

Query: 595 AEAWNNLSTSYIRLKQKVKAFRTLQE--------ALKCNYEHWQ--IWENYILTSTDVGE 644
             +W   + +Y  LK    A + L+E          K +YE+ +  +++N ++   D+ +
Sbjct: 148 RASWIGYAIAYHLLKDYDMALKLLEEFRQTQQVPPNKIDYEYSELILYQNQVMREADLLQ 207

Query: 645 FSEAIKAYHRLLDLRDKYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSR 704
            S         L+  + Y+     K+LV  +        G++   L G+L+E      + 
Sbjct: 208 ES---------LEHIEMYEKQICDKLLVEEI-------KGEILLKL-GRLKEASEVFKNL 250

Query: 705 VTNDGEIWRLYAHVYGNGQSEKPDENEKAFQCLSKAY 741
           +  + E W  Y  +    Q    +E  + ++ +SK +
Sbjct: 251 IDRNAENWCYYEGLEKALQISTLEERLQIYEEISKQH 287



 Score = 33.9 bits (76), Expect = 0.65
 Identities = 35/156 (22%), Positives = 69/156 (44%), Gaps = 11/156 (7%)

Query: 514 CYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLA 573
           CY  A +L +  + +  R  +LL ++ ++ +   E   + +++ P Q   W     AY  
Sbjct: 102 CYRNALKLDK-DNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHL 160

Query: 574 LEDYQGSAK---AFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQ 630
           L+DY  + K    F++   + P+  +     S   +   Q ++    LQE+L    EH +
Sbjct: 161 LKDYDMALKLLEEFRQTQQVPPNKID--YEYSELILYQNQVMREADLLQESL----EHIE 214

Query: 631 IWENYILTSTDVGEF-SEAIKAYHRLLDLRDKYKDV 665
           ++E  I     V E   E +    RL +  + +K++
Sbjct: 215 MYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNL 250


>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
          Length = 1564

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 20/68 (29%), Positives = 33/68 (48%)

Query: 538 LRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEA 597
           +RNKE++E ++  +  +K        W  +G A   LE    +  A+++   LEPD   A
Sbjct: 17  IRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLA 76

Query: 598 WNNLSTSY 605
           W  L+  Y
Sbjct: 77  WQGLANLY 84



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 43/167 (25%), Positives = 64/167 (38%), Gaps = 44/167 (26%)

Query: 450 LFELG--CTSSALQIFEKLEMWEDVVICYERAGQH----GKAEEILRQELEKKETPSLYC 503
           L  LG  C   AL++      W D+ I Y R  QH    G     L++ LEK    SL+C
Sbjct: 758 LLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEK----SLHC 813

Query: 504 LLGDV------------LGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFE 551
           L   V            LG  +CY     +  Y  A+                    CF 
Sbjct: 814 LKKAVRLDSNNHLYWNALGVVACYSG---IGNYALAQ-------------------HCFI 851

Query: 552 RSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAW 598
           +S++   +    W +LG  YL  E+ + + +AF+   +L+P     W
Sbjct: 852 KSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCW 898



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 34/171 (19%), Positives = 64/171 (37%), Gaps = 9/171 (5%)

Query: 501 LYCLLG----DVLGDHS----CYDKAWELSRYRSARAQRSKAL-LHLRNKEFQECVECFE 551
           ++C LG    DV+GD +    CY KA+EL    +     +  L + L + E    +    
Sbjct: 495 VFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTV 554

Query: 552 RSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQK 611
                       W   G  YL    +  +    Q  +  +P +   W +L  +Y+     
Sbjct: 555 TQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGY 614

Query: 612 VKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKY 662
             A ++  +A + N E              +G++ EA+  Y  ++  ++ Y
Sbjct: 615 TTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDY 665


>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
           sapiens]
          Length = 807

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 62/267 (23%), Positives = 112/267 (41%), Gaps = 40/267 (14%)

Query: 404 ERAMRQTQALADQ----FEDKTTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCT--S 457
           E+ + Q +++A+Q    F     S  E L I Y             + S L++      S
Sbjct: 119 EKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVL-----------IGSGLYDEAIRHFS 167

Query: 458 SALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDK 517
           + LQI   L    + V    +A Q   +  + R         +LY +  D    H  + +
Sbjct: 168 TMLQILSPLGRINEAVNDLTKAIQLQPSARLYRHR------GTLYFISEDYATAHEDFQQ 221

Query: 518 AWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDY 577
           + EL++ +   A   K L        +E +E F+ ++K     +  + SLG AY  L ++
Sbjct: 222 SLELNKNQPI-AMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNF 280

Query: 578 QGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYI- 636
           + + ++FQ+ + L        N++ T  +R    +    +LQEALK N++     E Y  
Sbjct: 281 EAATESFQKALLLNQ------NHVQTLQLR-GMMLYHHGSLQEALK-NFKRCLQLEPYNE 332

Query: 637 -------LTSTDVGEFSEAIKAYHRLL 656
                  L+   +G+F E IKA  +++
Sbjct: 333 VCQYMKGLSHVAMGQFYEGIKAQTKVM 359



 Score = 30.8 bits (68), Expect = 5.5
 Identities = 25/126 (19%), Positives = 55/126 (43%), Gaps = 3/126 (2%)

Query: 545 ECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTS 604
           E V    +++++ P    ++   G  Y   EDY  + + FQ+ + L  +   A      +
Sbjct: 181 EAVNDLTKAIQLQP-SARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLT 239

Query: 605 YIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664
           +       +A  + +EALK   +    +++      ++G F  A +++ + L L   +  
Sbjct: 240 FFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNH-- 297

Query: 665 VQVLKI 670
           VQ L++
Sbjct: 298 VQTLQL 303


>gi|24308141 small glutamine-rich tetratricopeptide repeat
           (TPR)-containing, beta [Homo sapiens]
          Length = 304

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 23/99 (23%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 568 GCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYE 627
           G  ++  E+Y  +   + + + L+P+NA  + N + +  +L     A +  ++A+  + +
Sbjct: 92  GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSK 151

Query: 628 HWQIWENYILTSTDVGEFSEAIKAYHRLLDL---RDKYK 663
           + + +    L  T + +F EA+ +Y + LDL    D YK
Sbjct: 152 YSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYK 190



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 18/110 (16%), Positives = 51/110 (46%)

Query: 537 HLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAE 596
           H++ + +   V+C+ ++++++P     + +   A   L  Y  + K  ++ + ++   ++
Sbjct: 95  HMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSK 154

Query: 597 AWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFS 646
           A+  +  +   L +  +A  + Q+AL  + E+     N  +    + E S
Sbjct: 155 AYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVS 204


>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
           sapiens]
          Length = 860

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 41/165 (24%), Positives = 77/165 (46%), Gaps = 17/165 (10%)

Query: 500 SLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPM 559
           +LY +  D    H  + ++ EL++ +   A   K L        +E +E F+ ++K    
Sbjct: 257 TLYFISEDYATAHEDFQQSLELNKNQPI-AMLYKGLTFFHRGLLKEAIESFKEALKQKVD 315

Query: 560 QLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQ 619
            +  + SLG AY  L +++ + ++FQ+ + L        N++ T  +R    +    +LQ
Sbjct: 316 FIDAYKSLGQAYRELGNFEAATESFQKALLLNQ------NHVQTLQLR-GMMLYHHGSLQ 368

Query: 620 EALKCNYEHWQIWENYI--------LTSTDVGEFSEAIKAYHRLL 656
           EALK N++     E Y         L+   +G+F E IKA  +++
Sbjct: 369 EALK-NFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVM 412



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 45/217 (20%), Positives = 85/217 (39%), Gaps = 21/217 (9%)

Query: 470 EDVVICYERAGQHGKAEEILRQELEKKETPSLYCLL---GDVLGDHSCYD-KAWELSRYR 525
           E++ I Y   G     E I       +E P L   +   G   G    +D K  EL+ + 
Sbjct: 145 EELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFE 204

Query: 526 SARA------------QRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLA 573
            +R             QR++ L  L      E V    +++++ P    ++   G  Y  
Sbjct: 205 LSRVITLEPDRPEVFEQRAEILSPLGR--INEAVNDLTKAIQLQP-SARLYRHRGTLYFI 261

Query: 574 LEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWE 633
            EDY  + + FQ+ + L  +   A      ++       +A  + +EALK   +    ++
Sbjct: 262 SEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYK 321

Query: 634 NYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQVLKI 670
           +      ++G F  A +++ + L L   +  VQ L++
Sbjct: 322 SLGQAYRELGNFEAATESFQKALLLNQNH--VQTLQL 356


>gi|124256489 crooked neck-like 1 protein [Homo sapiens]
          Length = 848

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 31/153 (20%), Positives = 67/153 (43%), Gaps = 3/153 (1%)

Query: 505 LGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVW 564
           L ++    S Y++A ++  YR+       A + ++N++       ++R++   P     W
Sbjct: 255 LKEIQRARSIYERALDVD-YRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFW 313

Query: 565 FSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKC 624
           +        L +  G+ + F+R +  +P+  +AW++     +R K+  +A RT+ E    
Sbjct: 314 YKYTYMEEMLGNVAGARQVFERWMEWQPEE-QAWHSYINFELRYKEVDRA-RTIYERFVL 371

Query: 625 NYEHWQIWENYILTSTDVGEFSEAIKAYHRLLD 657
            +   + W  Y         F+ A K Y R ++
Sbjct: 372 VHPDVKNWIKYARFEEKHAYFAHARKVYERAVE 404


>gi|4503729 FK506 binding protein 52 [Homo sapiens]
          Length = 459

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 41/183 (22%), Positives = 82/183 (44%), Gaps = 19/183 (10%)

Query: 435 QVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELE 494
           Q+PP+  ++ +L    FE    S  +   EKLE      I  ER   + K  +  +  L+
Sbjct: 236 QIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQ---STIVKERGTVYFKEGKYKQALLQ 292

Query: 495 KKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQR-----SKALLHLRNKEFQECVEC 549
            K+  S              Y+ ++     + A+A R     + A+ HL+ + F   +E 
Sbjct: 293 YKKIVSWLE-----------YESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIES 341

Query: 550 FERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLK 609
             ++++++       F  G A+LA+ D++ +   FQ+ + L P+N  A   L+    R++
Sbjct: 342 CNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIR 401

Query: 610 QKV 612
           +++
Sbjct: 402 RQL 404


>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
          Length = 499

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 20/97 (20%), Positives = 49/97 (50%)

Query: 571 YLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQ 630
           Y   +DY+ + K + + + L P NA  + N S +Y+R +    A      A++ + ++ +
Sbjct: 38  YFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 97

Query: 631 IWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQV 667
            +     ++  +G+F  A++ Y  ++ ++   KD ++
Sbjct: 98  GYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKM 134


>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
          Length = 2481

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 48/223 (21%), Positives = 93/223 (41%), Gaps = 39/223 (17%)

Query: 500  SLYCLLGDVLGDHSCYDKAWELSRYRS-----ARAQRSKALLHLRNKEFQECVECFERSV 554
            ++Y  LG       CY++  +L +        A+   +  +  +     +E +  FE+ +
Sbjct: 802  AVYMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQL 861

Query: 555  KINPMQLG---------VWFSLGCAYLALEDYQGSAKAFQRCVTLE------PDNAEAWN 599
             +     G          + +LG  Y AL DY+ + K +++ +++        D A+A+ 
Sbjct: 862  AMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYR 921

Query: 600  NLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLR 659
             L   +       +A  +LQ+AL C       +E  ++ + ++GE     +AY  L  L 
Sbjct: 922  GLGNGH-------RAMGSLQQALVC-------FEKRLVVAHELGEAFNKAQAYGELGSLH 967

Query: 660  DKYKDV-QVLKILVRA--VIDGMTDRS--GDVATGLKGKLQEL 697
             +  +  Q +  L R   +   M DR+   D A GL G  Q++
Sbjct: 968  SQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQM 1010



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 20/96 (20%)

Query: 566 SLGCAYLALEDYQGSAKAFQRCVTL------EPDNAEAWNNLSTSYIRLKQKVKAFRTLQ 619
           SLG  Y A+ DY  +  + ++CV L      E   A    N+   YI       A    +
Sbjct: 319 SLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYI-------AMGDFE 371

Query: 620 EALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRL 655
            A++C+ +H +I       + D+G   E  +AY  L
Sbjct: 372 NAVQCHEQHLKI-------AKDLGNKREEARAYSNL 400



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 34/149 (22%), Positives = 65/149 (43%), Gaps = 21/149 (14%)

Query: 533 KALLHL-RNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLE 591
           KALL+  + +E Q+ +    +S+  +  +     +LG  ++  +D  G+ K +++ + L 
Sbjct: 685 KALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLA 744

Query: 592 PD------NAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYE----------HWQIWENY 635
                    A A+  L T+Y  +++  KA     + L+   E          H  +   Y
Sbjct: 745 HQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVY 804

Query: 636 ILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664
           +     +G+++ A K Y   LDL  K KD
Sbjct: 805 MA----LGKYTMAFKCYEEQLDLGQKLKD 829


>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
          Length = 313

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 22/100 (22%), Positives = 53/100 (53%), Gaps = 2/100 (2%)

Query: 526 SARAQRSKALLH--LRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKA 583
           SA A+R K   +  ++ + F+  V  + +++++NP     + +   AY  L +Y G+ + 
Sbjct: 88  SAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQD 147

Query: 584 FQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK 623
            +R + ++P  ++A+  +  +   L + V+A    ++AL+
Sbjct: 148 CERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALE 187



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 24/97 (24%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 515 YDKAWELSRYRSAR-AQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLA 573
           Y KA EL+   +     R+ A   L N  +   V+  ER++ I+P     +  +G A  +
Sbjct: 114 YGKAIELNPANAVYFCNRAAAYSKLGN--YAGAVQDCERAICIDPAYSKAYGRMGLALSS 171

Query: 574 LEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQ 610
           L  +  +   +++ + L+PDN    +NL  + ++L++
Sbjct: 172 LNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLRE 208


>gi|6912458 calcineurin binding protein 1 [Homo sapiens]
          Length = 2220

 Score = 38.5 bits (88), Expect = 0.026
 Identities = 21/95 (22%), Positives = 42/95 (44%)

Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWEN 634
           ED + + + +   V L+  +   W  +    +RL +   A    +E L+CN +HW   +N
Sbjct: 104 EDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDN 163

Query: 635 YILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQVLK 669
            I     + +++  +    + L+   +Y    VLK
Sbjct: 164 LITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLK 198



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 20/98 (20%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 531 RSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTL 590
           ++ A L  + ++ +  +E +  +V ++   + +W+ +G   L L     +  AF+  +  
Sbjct: 94  KNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRC 153

Query: 591 EPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK--CNY 626
            PD+    +NL T    L         + +AL+  C Y
Sbjct: 154 NPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRY 191


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,548,314
Number of Sequences: 37866
Number of extensions: 1257687
Number of successful extensions: 3743
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 3436
Number of HSP's gapped (non-prelim): 321
length of query: 843
length of database: 18,247,518
effective HSP length: 111
effective length of query: 732
effective length of database: 14,044,392
effective search space: 10280494944
effective search space used: 10280494944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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