BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens] (843 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens] 1687 0.0 gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 53 1e-06 gi|118402596 cell division cycle protein 23 [Homo sapiens] 49 2e-05 gi|118766328 transmembrane and tetratricopeptide repeat containi... 49 3e-05 gi|118766330 transmembrane and tetratricopeptide repeat containi... 49 3e-05 gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 47 6e-05 gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 47 6e-05 gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 47 6e-05 gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 47 6e-05 gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sap... 47 1e-04 gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sap... 47 1e-04 gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sap... 47 1e-04 gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sap... 47 1e-04 gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapi... 47 1e-04 gi|224809432 transmembrane and tetratricopeptide repeat containi... 46 1e-04 gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens] 46 2e-04 gi|83415184 transmembrane and tetratricopeptide repeat containin... 45 2e-04 gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho... 43 0.001 gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [H... 43 0.001 gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Ho... 43 0.001 gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] 42 0.002 gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 42 0.002 gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 42 0.002 gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 42 0.003 gi|124256489 crooked neck-like 1 protein [Homo sapiens] 41 0.004 gi|4503729 FK506 binding protein 52 [Homo sapiens] 41 0.005 gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 40 0.009 gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 40 0.012 gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 40 0.012 gi|6912458 calcineurin binding protein 1 [Homo sapiens] 39 0.026 >gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens] Length = 843 Score = 1687 bits (4368), Expect = 0.0 Identities = 843/843 (100%), Positives = 843/843 (100%) Query: 1 MWTPELAILRGFPTEAERQQWKQEGVVGSESGSFLQLLLEGNYEAIFLNSMTQNIFNSTT 60 MWTPELAILRGFPTEAERQQWKQEGVVGSESGSFLQLLLEGNYEAIFLNSMTQNIFNSTT Sbjct: 1 MWTPELAILRGFPTEAERQQWKQEGVVGSESGSFLQLLLEGNYEAIFLNSMTQNIFNSTT 60 Query: 61 TAEEKIDSYLEKQVVTFLDYSTDLDTTERQQLIFLLGVSSLQLFVQSNWTGPPVDLHPQD 120 TAEEKIDSYLEKQVVTFLDYSTDLDTTERQQLIFLLGVSSLQLFVQSNWTGPPVDLHPQD Sbjct: 61 TAEEKIDSYLEKQVVTFLDYSTDLDTTERQQLIFLLGVSSLQLFVQSNWTGPPVDLHPQD 120 Query: 121 FLSSVLFQQFSEVKGLDAFVLSLLTLDGESIYSLTSKPILLLLARIILVNVRHKLTAIQS 180 FLSSVLFQQFSEVKGLDAFVLSLLTLDGESIYSLTSKPILLLLARIILVNVRHKLTAIQS Sbjct: 121 FLSSVLFQQFSEVKGLDAFVLSLLTLDGESIYSLTSKPILLLLARIILVNVRHKLTAIQS 180 Query: 181 LPWWTLRCVNIHQHLLEERSPLLFTLAENCIDQVMKLQNLFVDDSGRYLAIQFHLECAYV 240 LPWWTLRCVNIHQHLLEERSPLLFTLAENCIDQVMKLQNLFVDDSGRYLAIQFHLECAYV Sbjct: 181 LPWWTLRCVNIHQHLLEERSPLLFTLAENCIDQVMKLQNLFVDDSGRYLAIQFHLECAYV 240 Query: 241 FLYYYEYRKAKDQLDIAKDISQLQIDLTGALGKRTRFQENYVAQLILDVRREGDVLSNCE 300 FLYYYEYRKAKDQLDIAKDISQLQIDLTGALGKRTRFQENYVAQLILDVRREGDVLSNCE Sbjct: 241 FLYYYEYRKAKDQLDIAKDISQLQIDLTGALGKRTRFQENYVAQLILDVRREGDVLSNCE 300 Query: 301 FTPAPTPQEHLTKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPV 360 FTPAPTPQEHLTKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPV Sbjct: 301 FTPAPTPQEHLTKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPV 360 Query: 361 HTLTEVELLAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDK 420 HTLTEVELLAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDK Sbjct: 361 HTLTEVELLAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDK 420 Query: 421 TTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAG 480 TTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAG Sbjct: 421 TTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAG 480 Query: 481 QHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRN 540 QHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRN Sbjct: 481 QHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRN 540 Query: 541 KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNN 600 KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNN Sbjct: 541 KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNN 600 Query: 601 LSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRD 660 LSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRD Sbjct: 601 LSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRD 660 Query: 661 KYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYG 720 KYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYG Sbjct: 661 KYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYG 720 Query: 721 NGQSEKPDENEKAFQCLSKAYKCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSS 780 NGQSEKPDENEKAFQCLSKAYKCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSS Sbjct: 721 NGQSEKPDENEKAFQCLSKAYKCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSS 780 Query: 781 SQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFR 840 SQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFR Sbjct: 781 SQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFR 840 Query: 841 NQY 843 NQY Sbjct: 841 NQY 843 >gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] Length = 519 Score = 53.1 bits (126), Expect = 1e-06 Identities = 53/262 (20%), Positives = 105/262 (40%), Gaps = 16/262 (6%) Query: 423 SVLERLKIFYCCQV--PPHWAIQRQLASLLFELGCTSSALQIFEKLEM-----WE---DV 472 ++ E L++F C V P +Q+A LF LG +A++++ + WE ++ Sbjct: 82 NIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNL 141 Query: 473 VICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRY------RS 526 +CY Q KA++ L L Y +LG + DKA E+ + + Sbjct: 142 GVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPEN 201 Query: 527 ARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQR 586 + LL+L+ +Q+ E ++ +P + G D+ + ++ Sbjct: 202 TELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRV 261 Query: 587 CVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFS 646 P++ WNN+ + K+ V A L+ A W+I N L + +++ Sbjct: 262 VACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYA 321 Query: 647 EAIKAYHRLLDLRDKYKDVQVL 668 A ++ + K ++ +L Sbjct: 322 SAFHFLSAAINFQPKMGELYML 343 Score = 42.7 bits (99), Expect = 0.001 Identities = 41/201 (20%), Positives = 80/201 (39%), Gaps = 11/201 (5%) Query: 464 EKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLL-GDVLGDHSCYDKAWELS 522 E E+ + + Y + G + KA E L L T L G ++ H +D A L+ Sbjct: 200 ENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVA--LT 257 Query: 523 RYR--------SARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLAL 574 +YR S + + K++ + C +R+ + P + ++LG +L + Sbjct: 258 KYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTM 317 Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWEN 634 + Y + + +P E + L+ + L+ A R EA+ + + + N Sbjct: 318 QQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLN 377 Query: 635 YILTSTDVGEFSEAIKAYHRL 655 Y + + GE A+ Y + Sbjct: 378 YAVLLYNQGEKKNALAQYQEM 398 Score = 40.8 bits (94), Expect = 0.005 Identities = 29/124 (23%), Positives = 51/124 (41%), Gaps = 1/124 (0%) Query: 536 LHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALE-DYQGSAKAFQRCVTLEPDN 594 LH K+++ C + ++ + LE + Q S + FQ C L P + Sbjct: 41 LHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQS 100 Query: 595 AEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHR 654 A+ ++ S L + A EA K N + W+I N + + +F++A H Sbjct: 101 ADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHN 160 Query: 655 LLDL 658 L+L Sbjct: 161 ALNL 164 Score = 33.5 bits (75), Expect = 0.85 Identities = 28/128 (21%), Positives = 54/128 (42%), Gaps = 7/128 (5%) Query: 533 KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEP 592 +AL+ QE +E F+ ++P + + L ++ + + + L Sbjct: 73 QALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQ 132 Query: 593 DNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN---YEHWQIWENYILTSTDVGEFSEAI 649 + E +NL YI LKQ KA L AL N + + + ++L G+ +AI Sbjct: 133 KDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLE----GDLDKAI 188 Query: 650 KAYHRLLD 657 + Y + ++ Sbjct: 189 EVYKKAVE 196 >gi|118402596 cell division cycle protein 23 [Homo sapiens] Length = 597 Score = 48.9 bits (115), Expect = 2e-05 Identities = 53/247 (21%), Positives = 98/247 (39%), Gaps = 46/247 (18%) Query: 363 LTEVELLAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDKTT 422 +T+ E+L F LS P W + + T+L+ +E A+++ Q L D K++ Sbjct: 213 ITDKEMLKF----LSLPDTWMKEFFLAHIYTELQL-----IEEALQKYQNLIDVGFSKSS 263 Query: 423 SVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAGQH 482 ++ ++ + Y + AL IF +L + R Sbjct: 264 YIVSQIAVAY------------------HNIRDIDKALSIFNELRKQDPY-----RIENM 300 Query: 483 GKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKE 542 +L K E L L ++ D + + Y S R+Q KA L+ Sbjct: 301 DTFSNLLYVRSMKSELSYLAHNLCEI--DKYRVETCCVIGNYYSLRSQHEKAALY----- 353 Query: 543 FQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLS 602 F+R++K+NP LG W +G Y+ +++ + +A++ + + + AW L Sbjct: 354 -------FQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLG 406 Query: 603 TSYIRLK 609 +Y LK Sbjct: 407 QTYEILK 413 Score = 35.0 bits (79), Expect = 0.29 Identities = 24/120 (20%), Positives = 50/120 (41%), Gaps = 1/120 (0%) Query: 513 SCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYL 572 S +++ + YR LL++R+ + E +I+ ++ +G Y Sbjct: 284 SIFNELRKQDPYRIENMDTFSNLLYVRSMK-SELSYLAHNLCEIDKYRVETCCVIGNYYS 342 Query: 573 ALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIW 632 ++ +A FQR + L P AW + Y+ +K A + + A++ N ++ W Sbjct: 343 LRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAW 402 >gi|118766328 transmembrane and tetratricopeptide repeat containing 4 isoform 2 [Homo sapiens] Length = 741 Score = 48.5 bits (114), Expect = 3e-05 Identities = 42/193 (21%), Positives = 74/193 (38%), Gaps = 11/193 (5%) Query: 475 CYERAGQHGKAEEILRQELEKKE-TPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSK 533 C R+G+ E++ R L ++ +G L D A + YR A K Sbjct: 457 CVLRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAA--IRYYREAVRLNPK 514 Query: 534 ALLHLRN--------KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQ 585 + + N E QE E +V+I P W +LG +L+ ++ + ++++ Sbjct: 515 YVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYR 574 Query: 586 RCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEF 645 + + + NL Y L + V A + A EH W N I+ + G Sbjct: 575 TAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNL 634 Query: 646 SEAIKAYHRLLDL 658 ++A L+L Sbjct: 635 AQAEAVGREALEL 647 Score = 40.4 bits (93), Expect = 0.007 Identities = 39/184 (21%), Positives = 74/184 (40%), Gaps = 14/184 (7%) Query: 547 VECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYI 606 + + +V++NP + +LG + Q + + V ++PD A AW NL Sbjct: 502 IRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQN 561 Query: 607 RLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQ 666 LK+ A ++ + A+K ++ + N D+ +A+ A+ L+ ++ Sbjct: 562 SLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAW 621 Query: 667 VLKILVRAVIDGMTDRSGDVATGLKGKLQELFGR-VTSRVTNDGEIWRLYAHVYGNGQSE 725 I+ + D +G++A E GR + ND + A+V G Q Sbjct: 622 NNMII-------LLDNTGNLAQA------EAVGREALELIPNDHSLMFSLANVLGKSQKY 668 Query: 726 KPDE 729 K E Sbjct: 669 KESE 672 Score = 38.9 bits (89), Expect = 0.020 Identities = 26/127 (20%), Positives = 52/127 (40%) Query: 538 LRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEA 597 LR+ E++ + F ++ + P+ V +++G + + + ++ V L P A Sbjct: 459 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHA 518 Query: 598 WNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLD 657 NNL + +A L A++ + W N + + F A ++Y + Sbjct: 519 MNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIK 578 Query: 658 LRDKYKD 664 R KY D Sbjct: 579 HRRKYPD 585 >gi|118766330 transmembrane and tetratricopeptide repeat containing 4 isoform 1 [Homo sapiens] Length = 760 Score = 48.5 bits (114), Expect = 3e-05 Identities = 42/193 (21%), Positives = 74/193 (38%), Gaps = 11/193 (5%) Query: 475 CYERAGQHGKAEEILRQELEKKE-TPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSK 533 C R+G+ E++ R L ++ +G L D A + YR A K Sbjct: 476 CVLRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAA--IRYYREAVRLNPK 533 Query: 534 ALLHLRN--------KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQ 585 + + N E QE E +V+I P W +LG +L+ ++ + ++++ Sbjct: 534 YVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYR 593 Query: 586 RCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEF 645 + + + NL Y L + V A + A EH W N I+ + G Sbjct: 594 TAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNL 653 Query: 646 SEAIKAYHRLLDL 658 ++A L+L Sbjct: 654 AQAEAVGREALEL 666 Score = 40.4 bits (93), Expect = 0.007 Identities = 39/184 (21%), Positives = 74/184 (40%), Gaps = 14/184 (7%) Query: 547 VECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYI 606 + + +V++NP + +LG + Q + + V ++PD A AW NL Sbjct: 521 IRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQN 580 Query: 607 RLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQ 666 LK+ A ++ + A+K ++ + N D+ +A+ A+ L+ ++ Sbjct: 581 SLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAW 640 Query: 667 VLKILVRAVIDGMTDRSGDVATGLKGKLQELFGR-VTSRVTNDGEIWRLYAHVYGNGQSE 725 I+ + D +G++A E GR + ND + A+V G Q Sbjct: 641 NNMII-------LLDNTGNLAQA------EAVGREALELIPNDHSLMFSLANVLGKSQKY 687 Query: 726 KPDE 729 K E Sbjct: 688 KESE 691 Score = 38.9 bits (89), Expect = 0.020 Identities = 26/127 (20%), Positives = 52/127 (40%) Query: 538 LRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEA 597 LR+ E++ + F ++ + P+ V +++G + + + ++ V L P A Sbjct: 478 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHA 537 Query: 598 WNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLD 657 NNL + +A L A++ + W N + + F A ++Y + Sbjct: 538 MNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIK 597 Query: 658 LRDKYKD 664 R KY D Sbjct: 598 HRRKYPD 604 >gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] Length = 1036 Score = 47.4 bits (111), Expect = 6e-05 Identities = 49/210 (23%), Positives = 82/210 (39%), Gaps = 17/210 (8%) Query: 467 EMWEDVVICYERAGQHGKAEEILRQELEKK--------ETPSLYCLLGDVLGDHSCYDKA 518 E + ++ Y+ GQ +A E R L K + GD+ G Y A Sbjct: 80 EAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 139 Query: 519 WE----LSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLAL 574 + L RS KAL L +E C+ ++++ P W +LGC + A Sbjct: 140 LQYNPDLYCVRSDLGNLLKALGRL-----EEAKACYLKAIETQPNFAVAWSNLGCVFNAQ 194 Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWEN 634 + + F++ VTL+P+ +A+ NL + +A AL + H + N Sbjct: 195 GEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGN 254 Query: 635 YILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664 + G AI Y R ++L+ + D Sbjct: 255 LACVYYEQGLIDLAIDTYRRAIELQPHFPD 284 Score = 38.9 bits (89), Expect = 0.020 Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 11/176 (6%) Query: 499 PSLYCLLGDV------LGD----HSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVE 548 P LYC+ D+ LG +CY KA E ++ A A + + E + Sbjct: 144 PDLYCVRSDLGNLLKALGRLEEAKACYLKAIE-TQPNFAVAWSNLGCVFNAQGEIWLAIH 202 Query: 549 CFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRL 608 FE++V ++P L + +LG + + A+ R ++L P++A NL+ Y Sbjct: 203 HFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQ 262 Query: 609 KQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664 A T + A++ + N + G +EA Y+ L L + D Sbjct: 263 GLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHAD 318 Score = 38.9 bits (89), Expect = 0.020 Identities = 28/123 (22%), Positives = 58/123 (47%), Gaps = 10/123 (8%) Query: 515 YDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLAL 574 Y KA E+ +A ++L + K QE + ++ +++I+P + ++G + Sbjct: 340 YRKALEVFPEFAAAHSNLASVLQQQGK-LQEALMHYKEAIRISPTFADAYSNMGNTLKEM 398 Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK---------CN 625 +D QG+ + + R + + P A+A +NL++ + +A + + ALK CN Sbjct: 399 QDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCN 458 Query: 626 YEH 628 H Sbjct: 459 LAH 461 Score = 36.6 bits (83), Expect = 0.10 Identities = 24/116 (20%), Positives = 47/116 (40%) Query: 543 FQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLS 602 F V + R++ ++P V +L C Y + ++R + L+P +A+ NL+ Sbjct: 231 FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLA 290 Query: 603 TSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDL 658 + +A AL+ H N + G EA++ Y + L++ Sbjct: 291 NALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 346 Score = 31.6 bits (70), Expect = 3.2 Identities = 21/127 (16%), Positives = 52/127 (40%) Query: 536 LHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNA 595 +H + + ++K NP+ + +LG Y Q + + ++ + L+PD Sbjct: 54 IHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFI 113 Query: 596 EAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRL 655 + + NL+ + + A + AL+ N + + + + +G EA Y + Sbjct: 114 DGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKA 173 Query: 656 LDLRDKY 662 ++ + + Sbjct: 174 IETQPNF 180 Score = 31.2 bits (69), Expect = 4.2 Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 5/104 (4%) Query: 566 SLGCAYLALEDYQ-GSAKAFQR-CVTL---EPDNAEAWNNLSTSYIRLKQKVKAFRTLQE 620 S G A LA +YQ G +A +R C+ L EPDN LS+ + + ++ ++ Sbjct: 11 STGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTL 70 Query: 621 ALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664 A+K N + + N + G+ EAI+ Y L L+ + D Sbjct: 71 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFID 114 >gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] Length = 1046 Score = 47.4 bits (111), Expect = 6e-05 Identities = 49/210 (23%), Positives = 82/210 (39%), Gaps = 17/210 (8%) Query: 467 EMWEDVVICYERAGQHGKAEEILRQELEKK--------ETPSLYCLLGDVLGDHSCYDKA 518 E + ++ Y+ GQ +A E R L K + GD+ G Y A Sbjct: 90 EAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 149 Query: 519 WE----LSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLAL 574 + L RS KAL L +E C+ ++++ P W +LGC + A Sbjct: 150 LQYNPDLYCVRSDLGNLLKALGRL-----EEAKACYLKAIETQPNFAVAWSNLGCVFNAQ 204 Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWEN 634 + + F++ VTL+P+ +A+ NL + +A AL + H + N Sbjct: 205 GEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGN 264 Query: 635 YILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664 + G AI Y R ++L+ + D Sbjct: 265 LACVYYEQGLIDLAIDTYRRAIELQPHFPD 294 Score = 38.9 bits (89), Expect = 0.020 Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 11/176 (6%) Query: 499 PSLYCLLGDV------LGD----HSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVE 548 P LYC+ D+ LG +CY KA E ++ A A + + E + Sbjct: 154 PDLYCVRSDLGNLLKALGRLEEAKACYLKAIE-TQPNFAVAWSNLGCVFNAQGEIWLAIH 212 Query: 549 CFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRL 608 FE++V ++P L + +LG + + A+ R ++L P++A NL+ Y Sbjct: 213 HFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQ 272 Query: 609 KQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664 A T + A++ + N + G +EA Y+ L L + D Sbjct: 273 GLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHAD 328 Score = 38.9 bits (89), Expect = 0.020 Identities = 28/123 (22%), Positives = 58/123 (47%), Gaps = 10/123 (8%) Query: 515 YDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLAL 574 Y KA E+ +A ++L + K QE + ++ +++I+P + ++G + Sbjct: 350 YRKALEVFPEFAAAHSNLASVLQQQGK-LQEALMHYKEAIRISPTFADAYSNMGNTLKEM 408 Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK---------CN 625 +D QG+ + + R + + P A+A +NL++ + +A + + ALK CN Sbjct: 409 QDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCN 468 Query: 626 YEH 628 H Sbjct: 469 LAH 471 Score = 36.6 bits (83), Expect = 0.10 Identities = 24/116 (20%), Positives = 47/116 (40%) Query: 543 FQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLS 602 F V + R++ ++P V +L C Y + ++R + L+P +A+ NL+ Sbjct: 241 FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLA 300 Query: 603 TSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDL 658 + +A AL+ H N + G EA++ Y + L++ Sbjct: 301 NALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 356 Score = 31.6 bits (70), Expect = 3.2 Identities = 21/127 (16%), Positives = 52/127 (40%) Query: 536 LHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNA 595 +H + + ++K NP+ + +LG Y Q + + ++ + L+PD Sbjct: 64 IHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFI 123 Query: 596 EAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRL 655 + + NL+ + + A + AL+ N + + + + +G EA Y + Sbjct: 124 DGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKA 183 Query: 656 LDLRDKY 662 ++ + + Sbjct: 184 IETQPNF 190 Score = 30.0 bits (66), Expect = 9.4 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 5/102 (4%) Query: 568 GCAYLALEDYQ-GSAKAFQR-CVTL---EPDNAEAWNNLSTSYIRLKQKVKAFRTLQEAL 622 G A LA +YQ G +A +R C+ L EPDN LS+ + + ++ ++ A+ Sbjct: 23 GLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAI 82 Query: 623 KCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664 K N + + N + G+ EAI+ Y L L+ + D Sbjct: 83 KQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFID 124 >gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapiens] Length = 830 Score = 47.4 bits (111), Expect = 6e-05 Identities = 40/194 (20%), Positives = 82/194 (42%), Gaps = 17/194 (8%) Query: 445 QLASLLFELGCTSSALQIFEKLEMWEDVVI----CYERAGQHGKAE---EILRQELEK-- 495 Q+ FEL A +IF ++ E+ + Y H + + +L ++L Sbjct: 510 QIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMD 569 Query: 496 KETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLH-------LRNKEFQECVE 548 K +P +C G+ +D A + + R+ + + A + + +E + + Sbjct: 570 KNSPEAWCAAGNCFSLQREHDIAIKFFQ-RAIQVDPNYAYAYTLLGHEFVLTEELDKALA 628 Query: 549 CFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRL 608 CF ++++NP W+ LG Y E + + FQ+ + + P ++ ++ L Sbjct: 629 CFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHAL 688 Query: 609 KQKVKAFRTLQEAL 622 K+ KA TL +A+ Sbjct: 689 KKSEKALDTLNKAI 702 Score = 40.4 bits (93), Expect = 0.007 Identities = 21/95 (22%), Positives = 44/95 (46%) Query: 564 WFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK 623 W + G + ++ + K FQR + ++P+ A A+ L ++ ++ KA + A++ Sbjct: 576 WCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR 635 Query: 624 CNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDL 658 N H+ W + +FS A + + LD+ Sbjct: 636 VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDI 670 Score = 36.6 bits (83), Expect = 0.10 Identities = 24/121 (19%), Positives = 52/121 (42%), Gaps = 7/121 (5%) Query: 541 KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNN 600 +E ++ F+R+++++P + LG ++ E+ + F+ + + P + AW Sbjct: 587 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 646 Query: 601 LSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRD 660 L Y + ++ A Q+AL N + + +G A+K + LD + Sbjct: 647 LGMIYYKQEKFSLAEMHFQKALDINPQS-------SVLLCHIGVVQHALKKSEKALDTLN 699 Query: 661 K 661 K Sbjct: 700 K 700 >gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapiens] Length = 824 Score = 47.4 bits (111), Expect = 6e-05 Identities = 40/194 (20%), Positives = 82/194 (42%), Gaps = 17/194 (8%) Query: 445 QLASLLFELGCTSSALQIFEKLEMWEDVVI----CYERAGQHGKAE---EILRQELEK-- 495 Q+ FEL A +IF ++ E+ + Y H + + +L ++L Sbjct: 504 QIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMD 563 Query: 496 KETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLH-------LRNKEFQECVE 548 K +P +C G+ +D A + + R+ + + A + + +E + + Sbjct: 564 KNSPEAWCAAGNCFSLQREHDIAIKFFQ-RAIQVDPNYAYAYTLLGHEFVLTEELDKALA 622 Query: 549 CFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRL 608 CF ++++NP W+ LG Y E + + FQ+ + + P ++ ++ L Sbjct: 623 CFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHAL 682 Query: 609 KQKVKAFRTLQEAL 622 K+ KA TL +A+ Sbjct: 683 KKSEKALDTLNKAI 696 Score = 40.4 bits (93), Expect = 0.007 Identities = 21/95 (22%), Positives = 44/95 (46%) Query: 564 WFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK 623 W + G + ++ + K FQR + ++P+ A A+ L ++ ++ KA + A++ Sbjct: 570 WCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR 629 Query: 624 CNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDL 658 N H+ W + +FS A + + LD+ Sbjct: 630 VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDI 664 Score = 36.6 bits (83), Expect = 0.10 Identities = 24/121 (19%), Positives = 52/121 (42%), Gaps = 7/121 (5%) Query: 541 KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNN 600 +E ++ F+R+++++P + LG ++ E+ + F+ + + P + AW Sbjct: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640 Query: 601 LSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRD 660 L Y + ++ A Q+AL N + + +G A+K + LD + Sbjct: 641 LGMIYYKQEKFSLAEMHFQKALDINPQS-------SVLLCHIGVVQHALKKSEKALDTLN 693 Query: 661 K 661 K Sbjct: 694 K 694 >gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sapiens] Length = 639 Score = 46.6 bits (109), Expect = 1e-04 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%) Query: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571 YDK ++ R + L L+ + V FE +V+ +P + W LG Sbjct: 320 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 379 Query: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629 E + A +RC+ L+PDN A L+ S+ + +A TL++ L+ Y H Sbjct: 380 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 438 Query: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688 ++T + G + R+L L ++V ++ + AV T DV Sbjct: 439 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 492 Query: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726 GL G L L G V ND +W NG QSE+ Sbjct: 493 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540 Score = 37.4 bits (85), Expect = 0.059 Identities = 21/81 (25%), Positives = 36/81 (44%) Query: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601 E+ + V+CF ++ + P +W LG + + A++R + L+P + NL Sbjct: 503 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 562 Query: 602 STSYIRLKQKVKAFRTLQEAL 622 S I L +A EAL Sbjct: 563 GISCINLGAHREAVEHFLEAL 583 >gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sapiens] Length = 639 Score = 46.6 bits (109), Expect = 1e-04 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%) Query: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571 YDK ++ R + L L+ + V FE +V+ +P + W LG Sbjct: 320 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 379 Query: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629 E + A +RC+ L+PDN A L+ S+ + +A TL++ L+ Y H Sbjct: 380 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 438 Query: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688 ++T + G + R+L L ++V ++ + AV T DV Sbjct: 439 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 492 Query: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726 GL G L L G V ND +W NG QSE+ Sbjct: 493 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 540 Score = 37.4 bits (85), Expect = 0.059 Identities = 21/81 (25%), Positives = 36/81 (44%) Query: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601 E+ + V+CF ++ + P +W LG + + A++R + L+P + NL Sbjct: 503 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 562 Query: 602 STSYIRLKQKVKAFRTLQEAL 622 S I L +A EAL Sbjct: 563 GISCINLGAHREAVEHFLEAL 583 >gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sapiens] Length = 602 Score = 46.6 bits (109), Expect = 1e-04 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%) Query: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571 YDK ++ R + L L+ + V FE +V+ +P + W LG Sbjct: 283 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 342 Query: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629 E + A +RC+ L+PDN A L+ S+ + +A TL++ L+ Y H Sbjct: 343 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 401 Query: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688 ++T + G + R+L L ++V ++ + AV T DV Sbjct: 402 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 455 Query: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726 GL G L L G V ND +W NG QSE+ Sbjct: 456 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 503 Score = 37.4 bits (85), Expect = 0.059 Identities = 21/81 (25%), Positives = 36/81 (44%) Query: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601 E+ + V+CF ++ + P +W LG + + A++R + L+P + NL Sbjct: 466 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 525 Query: 602 STSYIRLKQKVKAFRTLQEAL 622 S I L +A EAL Sbjct: 526 GISCINLGAHREAVEHFLEAL 546 >gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sapiens] Length = 654 Score = 46.6 bits (109), Expect = 1e-04 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%) Query: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571 YDK ++ R + L L+ + V FE +V+ +P + W LG Sbjct: 335 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 394 Query: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629 E + A +RC+ L+PDN A L+ S+ + +A TL++ L+ Y H Sbjct: 395 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 453 Query: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688 ++T + G + R+L L ++V ++ + AV T DV Sbjct: 454 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 507 Query: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726 GL G L L G V ND +W NG QSE+ Sbjct: 508 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 555 Score = 37.4 bits (85), Expect = 0.059 Identities = 21/81 (25%), Positives = 36/81 (44%) Query: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601 E+ + V+CF ++ + P +W LG + + A++R + L+P + NL Sbjct: 518 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 577 Query: 602 STSYIRLKQKVKAFRTLQEAL 622 S I L +A EAL Sbjct: 578 GISCINLGAHREAVEHFLEAL 598 >gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapiens] Length = 631 Score = 46.6 bits (109), Expect = 1e-04 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 25/229 (10%) Query: 515 YDKAWELSRYRSARAQRS---KALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY 571 YDK ++ R + L L+ + V FE +V+ +P + W LG Sbjct: 312 YDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQ 371 Query: 572 LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCN--YEHW 629 E + A +RC+ L+PDN A L+ S+ + +A TL++ L+ Y H Sbjct: 372 AENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAH- 430 Query: 630 QIWENYILTSTDVGEFSEAIKAYHRLL-DLRDKYKDVQVLKILVRAVIDGMTDRSGDVAT 688 ++T + G + R+L L ++V ++ + AV T DV Sbjct: 431 ------LVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQC 484 Query: 689 GLKGKLQELFGRVTSRV----------TNDGEIWRLYAHVYGNG-QSEK 726 GL G L L G V ND +W NG QSE+ Sbjct: 485 GL-GVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEE 532 Score = 37.4 bits (85), Expect = 0.059 Identities = 21/81 (25%), Positives = 36/81 (44%) Query: 542 EFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNL 601 E+ + V+CF ++ + P +W LG + + A++R + L+P + NL Sbjct: 495 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 554 Query: 602 STSYIRLKQKVKAFRTLQEAL 622 S I L +A EAL Sbjct: 555 GISCINLGAHREAVEHFLEAL 575 >gi|224809432 transmembrane and tetratricopeptide repeat containing 3 [Homo sapiens] Length = 914 Score = 46.2 bits (108), Expect = 1e-04 Identities = 28/122 (22%), Positives = 56/122 (45%) Query: 535 LLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDN 594 L+ +E + + +++ + P + S G L + + +A+ + + L+ +N Sbjct: 537 LIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNN 596 Query: 595 AEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHR 654 A+ W NL+ +I LK+ +A + AL+ N +H N + + GE +A R Sbjct: 597 ADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKR 656 Query: 655 LL 656 LL Sbjct: 657 LL 658 Score = 45.8 bits (107), Expect = 2e-04 Identities = 26/112 (23%), Positives = 59/112 (52%), Gaps = 1/112 (0%) Query: 553 SVKINPMQLGVWFSLGCAYLALEDYQGSA-KAFQRCVTLEPDNAEAWNNLSTSYIRLKQK 611 + +I P L V+ +L A E A + +++ +++ PD +A+ + +++ + Sbjct: 520 AARIAPNHLNVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKP 579 Query: 612 VKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYK 663 +KA +AL+ + + +W N + ++ E +EA+K ++R L+L K+K Sbjct: 580 LKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHK 631 Score = 35.8 bits (81), Expect = 0.17 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQE--ALKCNYEHWQIW 632 +D G+ K F+R + ++P N + +NL Y K +KA R L E AL + E+ Q Sbjct: 751 KDILGAKKCFERILEMDPSNVQGKHNLCVVYFEEKDLLKAERCLLETLALAPHEEYIQRH 810 Query: 633 ENYILTSTDVGEFSEAI 649 N + F E I Sbjct: 811 LNIVRDKISSSSFIEPI 827 Score = 32.3 bits (72), Expect = 1.9 Identities = 26/144 (18%), Positives = 60/144 (41%), Gaps = 15/144 (10%) Query: 539 RNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAW 598 RN +++ F ++K+N +W ++G A ++++ + K F + ++PD+ A Sbjct: 424 RNWDWESEYTLFMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGAH 483 Query: 599 NNLSTSYIRLKQKVKAFRTL--------------QEALKCNYEHWQIWENYI-LTSTDVG 643 N+ +Y L + +A + + A + H ++ N L + Sbjct: 484 MNVGRTYKNLNRTKEAEESYMMAKSLMPQIIPGKKYAARIAPNHLNVYINLANLIRANES 543 Query: 644 EFSEAIKAYHRLLDLRDKYKDVQV 667 EA + Y + + +R +K + Sbjct: 544 RLEEADQLYRQAISMRPDFKQAYI 567 Score = 31.2 bits (69), Expect = 4.2 Identities = 34/153 (22%), Positives = 64/153 (41%), Gaps = 42/153 (27%) Query: 515 YDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKIN----------------- 557 Y KA EL R +A + A++H+ KE E ++ F R++++N Sbjct: 586 YLKALELDR-NNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAIVMQES 644 Query: 558 --------------------PMQLGVWFSLGCAYLALEDYQGSAKA--FQRCVTLEPDNA 595 P+ +F+LG LA++D + + ++ + L+ D Sbjct: 645 GEVKLRPEARKRLLSYINEEPLDANGYFNLG--MLAMDDKKDNEAEIWMKKAIKLQADFR 702 Query: 596 EAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEH 628 A NL+ Y + +++KA L+E L+ +H Sbjct: 703 SALFNLALLYSQTAKELKALPILEELLRYYPDH 735 >gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens] Length = 1121 Score = 45.8 bits (107), Expect = 2e-04 Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 6/139 (4%) Query: 533 KALLHLRNKEFQECVECFERSVK--INPMQLG-VWFSLGCAYLALEDYQGSAKAFQRCVT 589 K L+ + E C+ER++ ++ ++ ++ LG YL ++Y+ + K + + Sbjct: 969 KGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACK 1028 Query: 590 LEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAI 649 P + W L + RL++ +A L EA N + ++W L VG EA Sbjct: 1029 RSP-SCLTWLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAE 1087 Query: 650 KAYHRLLDLRDKYKDVQVL 668 +AY ++ L K KD +L Sbjct: 1088 QAYKYMIKL--KLKDEALL 1104 Score = 37.7 bits (86), Expect = 0.045 Identities = 20/76 (26%), Positives = 33/76 (43%) Query: 548 ECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIR 607 ECF++++ +N + G + LE+Y+ + F+ LEP N AW L Y Sbjct: 690 ECFQKALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEI 749 Query: 608 LKQKVKAFRTLQEALK 623 ++ EA K Sbjct: 750 QNNDIRMEMAFHEASK 765 >gi|83415184 transmembrane and tetratricopeptide repeat containing 1 [Homo sapiens] Length = 774 Score = 45.4 bits (106), Expect = 2e-04 Identities = 65/337 (19%), Positives = 135/337 (40%), Gaps = 37/337 (10%) Query: 530 QRSKALLHLRN-----KEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAF 584 Q ++AL +L N ++ +E + + S+K P + SL E ++ + + + Sbjct: 438 QHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIY 497 Query: 585 QRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGE 644 Q + PD+++ NN + KA Q+A+K + H N +GE Sbjct: 498 QTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGE 557 Query: 645 FSEAIKAYHRLLDLRDKYKDV--------------QVLKILVRAVIDGMTDRSGDVA--- 687 S A + Y R L + K + + + L+I A + R +A Sbjct: 558 NSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQ 617 Query: 688 ----TGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYGNGQSEKP--DENEKAFQCLSKAY 741 G + +++ + S T E +RL + +Y ++ D +KA Q K Sbjct: 618 VLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDP 677 Query: 742 KCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSS---SQEAVQMLSSVRLNLRGL 798 K ++ + + + ++ +A VA++ + +++ + +Q + ++ R Sbjct: 678 KVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAY 737 Query: 799 LSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDL 835 +A QL D S+ L +++ +D L LQ++ Sbjct: 738 YERALQLVPD------SKLLKENLAKLDRLEKRLQEV 768 Score = 30.4 bits (67), Expect = 7.2 Identities = 20/109 (18%), Positives = 51/109 (46%) Query: 550 FERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLK 609 ++R+++++P F+LG + E + + + + P+ A+A+++L++ + Sbjct: 429 YQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQE 488 Query: 610 QKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDL 658 + +A Q +K + + NY + D G +A+ Y + + L Sbjct: 489 RFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKL 537 >gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo sapiens] Length = 864 Score = 43.1 bits (100), Expect = 0.001 Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 27/217 (12%) Query: 535 LLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDN 594 LL +K++ E ++C+ ++K++ L + L + + D +G + + + L P Sbjct: 88 LLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQ 147 Query: 595 AEAWNNLSTSYIRLKQKVKAFRTLQE--------ALKCNYEHWQ--IWENYILTSTDVGE 644 +W + +Y LK A + L+E K +YE+ + +++N ++ D+ + Sbjct: 148 RASWIGYAIAYHLLKDYDMALKLLEEFRQTQQVPPNKIDYEYSELILYQNQVMREADLLQ 207 Query: 645 FSEAIKAYHRLLDLRDKYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSR 704 S L+ + Y+ K+LV + G++ L G+L+E + Sbjct: 208 ES---------LEHIEMYEKQICDKLLVEEI-------KGEILLKL-GRLKEASEVFKNL 250 Query: 705 VTNDGEIWRLYAHVYGNGQSEKPDENEKAFQCLSKAY 741 + + E W Y + Q +E + ++ +SK + Sbjct: 251 IDRNAENWCYYEGLEKALQISTLEERLQIYEEISKQH 287 Score = 33.9 bits (76), Expect = 0.65 Identities = 35/156 (22%), Positives = 69/156 (44%), Gaps = 11/156 (7%) Query: 514 CYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLA 573 CY A +L + + + R +LL ++ ++ + E + +++ P Q W AY Sbjct: 102 CYRNALKLDK-DNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHL 160 Query: 574 LEDYQGSAK---AFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQ 630 L+DY + K F++ + P+ + S + Q ++ LQE+L EH + Sbjct: 161 LKDYDMALKLLEEFRQTQQVPPNKID--YEYSELILYQNQVMREADLLQESL----EHIE 214 Query: 631 IWENYILTSTDVGEF-SEAIKAYHRLLDLRDKYKDV 665 ++E I V E E + RL + + +K++ Sbjct: 215 MYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNL 250 >gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [Homo sapiens] Length = 429 Score = 43.1 bits (100), Expect = 0.001 Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 27/217 (12%) Query: 535 LLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDN 594 LL +K++ E ++C+ ++K++ L + L + + D +G + + + L P Sbjct: 88 LLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQ 147 Query: 595 AEAWNNLSTSYIRLKQKVKAFRTLQE--------ALKCNYEHWQ--IWENYILTSTDVGE 644 +W + +Y LK A + L+E K +YE+ + +++N ++ D+ + Sbjct: 148 RASWIGYAIAYHLLKDYDMALKLLEEFRQTQQVPPNKIDYEYSELILYQNQVMREADLLQ 207 Query: 645 FSEAIKAYHRLLDLRDKYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSR 704 S L+ + Y+ K+LV + G++ L G+L+E + Sbjct: 208 ES---------LEHIEMYEKQICDKLLVEEI-------KGEILLKL-GRLKEASEVFKNL 250 Query: 705 VTNDGEIWRLYAHVYGNGQSEKPDENEKAFQCLSKAY 741 + + E W Y + Q +E + ++ +SK + Sbjct: 251 IDRNAENWCYYEGLEKALQISTLEERLQIYEEISKQH 287 Score = 33.9 bits (76), Expect = 0.65 Identities = 35/156 (22%), Positives = 69/156 (44%), Gaps = 11/156 (7%) Query: 514 CYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLA 573 CY A +L + + + R +LL ++ ++ + E + +++ P Q W AY Sbjct: 102 CYRNALKLDK-DNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHL 160 Query: 574 LEDYQGSAK---AFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQ 630 L+DY + K F++ + P+ + S + Q ++ LQE+L EH + Sbjct: 161 LKDYDMALKLLEEFRQTQQVPPNKID--YEYSELILYQNQVMREADLLQESL----EHIE 214 Query: 631 IWENYILTSTDVGEF-SEAIKAYHRLLDLRDKYKDV 665 ++E I V E E + RL + + +K++ Sbjct: 215 MYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNL 250 >gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Homo sapiens] Length = 311 Score = 43.1 bits (100), Expect = 0.001 Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 27/217 (12%) Query: 535 LLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDN 594 LL +K++ E ++C+ ++K++ L + L + + D +G + + + L P Sbjct: 88 LLQRSDKKYDEAIKCYRNALKLDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQ 147 Query: 595 AEAWNNLSTSYIRLKQKVKAFRTLQE--------ALKCNYEHWQ--IWENYILTSTDVGE 644 +W + +Y LK A + L+E K +YE+ + +++N ++ D+ + Sbjct: 148 RASWIGYAIAYHLLKDYDMALKLLEEFRQTQQVPPNKIDYEYSELILYQNQVMREADLLQ 207 Query: 645 FSEAIKAYHRLLDLRDKYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSR 704 S L+ + Y+ K+LV + G++ L G+L+E + Sbjct: 208 ES---------LEHIEMYEKQICDKLLVEEI-------KGEILLKL-GRLKEASEVFKNL 250 Query: 705 VTNDGEIWRLYAHVYGNGQSEKPDENEKAFQCLSKAY 741 + + E W Y + Q +E + ++ +SK + Sbjct: 251 IDRNAENWCYYEGLEKALQISTLEERLQIYEEISKQH 287 Score = 33.9 bits (76), Expect = 0.65 Identities = 35/156 (22%), Positives = 69/156 (44%), Gaps = 11/156 (7%) Query: 514 CYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLA 573 CY A +L + + + R +LL ++ ++ + E + +++ P Q W AY Sbjct: 102 CYRNALKLDK-DNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPTQRASWIGYAIAYHL 160 Query: 574 LEDYQGSAK---AFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQ 630 L+DY + K F++ + P+ + S + Q ++ LQE+L EH + Sbjct: 161 LKDYDMALKLLEEFRQTQQVPPNKID--YEYSELILYQNQVMREADLLQESL----EHIE 214 Query: 631 IWENYILTSTDVGEF-SEAIKAYHRLLDLRDKYKDV 665 ++E I V E E + RL + + +K++ Sbjct: 215 MYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNL 250 >gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] Length = 1564 Score = 42.0 bits (97), Expect = 0.002 Identities = 20/68 (29%), Positives = 33/68 (48%) Query: 538 LRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEA 597 +RNKE++E ++ + +K W +G A LE + A+++ LEPD A Sbjct: 17 IRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLA 76 Query: 598 WNNLSTSY 605 W L+ Y Sbjct: 77 WQGLANLY 84 Score = 41.2 bits (95), Expect = 0.004 Identities = 43/167 (25%), Positives = 64/167 (38%), Gaps = 44/167 (26%) Query: 450 LFELG--CTSSALQIFEKLEMWEDVVICYERAGQH----GKAEEILRQELEKKETPSLYC 503 L LG C AL++ W D+ I Y R QH G L++ LEK SL+C Sbjct: 758 LLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEK----SLHC 813 Query: 504 LLGDV------------LGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFE 551 L V LG +CY + Y A+ CF Sbjct: 814 LKKAVRLDSNNHLYWNALGVVACYSG---IGNYALAQ-------------------HCFI 851 Query: 552 RSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAW 598 +S++ + W +LG YL E+ + + +AF+ +L+P W Sbjct: 852 KSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCW 898 Score = 38.5 bits (88), Expect = 0.026 Identities = 34/171 (19%), Positives = 64/171 (37%), Gaps = 9/171 (5%) Query: 501 LYCLLG----DVLGDHS----CYDKAWELSRYRSARAQRSKAL-LHLRNKEFQECVECFE 551 ++C LG DV+GD + CY KA+EL + + L + L + E + Sbjct: 495 VFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTV 554 Query: 552 RSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQK 611 W G YL + + Q + +P + W +L +Y+ Sbjct: 555 TQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGY 614 Query: 612 VKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKY 662 A ++ +A + N E +G++ EA+ Y ++ ++ Y Sbjct: 615 TTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDY 665 >gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo sapiens] Length = 807 Score = 42.0 bits (97), Expect = 0.002 Identities = 62/267 (23%), Positives = 112/267 (41%), Gaps = 40/267 (14%) Query: 404 ERAMRQTQALADQ----FEDKTTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCT--S 457 E+ + Q +++A+Q F S E L I Y + S L++ S Sbjct: 119 EKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVL-----------IGSGLYDEAIRHFS 167 Query: 458 SALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDK 517 + LQI L + V +A Q + + R +LY + D H + + Sbjct: 168 TMLQILSPLGRINEAVNDLTKAIQLQPSARLYRHR------GTLYFISEDYATAHEDFQQ 221 Query: 518 AWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDY 577 + EL++ + A K L +E +E F+ ++K + + SLG AY L ++ Sbjct: 222 SLELNKNQPI-AMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNF 280 Query: 578 QGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYI- 636 + + ++FQ+ + L N++ T +R + +LQEALK N++ E Y Sbjct: 281 EAATESFQKALLLNQ------NHVQTLQLR-GMMLYHHGSLQEALK-NFKRCLQLEPYNE 332 Query: 637 -------LTSTDVGEFSEAIKAYHRLL 656 L+ +G+F E IKA +++ Sbjct: 333 VCQYMKGLSHVAMGQFYEGIKAQTKVM 359 Score = 30.8 bits (68), Expect = 5.5 Identities = 25/126 (19%), Positives = 55/126 (43%), Gaps = 3/126 (2%) Query: 545 ECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTS 604 E V +++++ P ++ G Y EDY + + FQ+ + L + A + Sbjct: 181 EAVNDLTKAIQLQP-SARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLT 239 Query: 605 YIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664 + +A + +EALK + +++ ++G F A +++ + L L + Sbjct: 240 FFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNH-- 297 Query: 665 VQVLKI 670 VQ L++ Sbjct: 298 VQTLQL 303 >gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta [Homo sapiens] Length = 304 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/99 (23%), Positives = 50/99 (50%), Gaps = 3/99 (3%) Query: 568 GCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYE 627 G ++ E+Y + + + + L+P+NA + N + + +L A + ++A+ + + Sbjct: 92 GNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSK 151 Query: 628 HWQIWENYILTSTDVGEFSEAIKAYHRLLDL---RDKYK 663 + + + L T + +F EA+ +Y + LDL D YK Sbjct: 152 YSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYK 190 Score = 35.4 bits (80), Expect = 0.22 Identities = 18/110 (16%), Positives = 51/110 (46%) Query: 537 HLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAE 596 H++ + + V+C+ ++++++P + + A L Y + K ++ + ++ ++ Sbjct: 95 HMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSK 154 Query: 597 AWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFS 646 A+ + + L + +A + Q+AL + E+ N + + E S Sbjct: 155 AYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVS 204 >gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo sapiens] Length = 860 Score = 41.6 bits (96), Expect = 0.003 Identities = 41/165 (24%), Positives = 77/165 (46%), Gaps = 17/165 (10%) Query: 500 SLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPM 559 +LY + D H + ++ EL++ + A K L +E +E F+ ++K Sbjct: 257 TLYFISEDYATAHEDFQQSLELNKNQPI-AMLYKGLTFFHRGLLKEAIESFKEALKQKVD 315 Query: 560 QLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQ 619 + + SLG AY L +++ + ++FQ+ + L N++ T +R + +LQ Sbjct: 316 FIDAYKSLGQAYRELGNFEAATESFQKALLLNQ------NHVQTLQLR-GMMLYHHGSLQ 368 Query: 620 EALKCNYEHWQIWENYI--------LTSTDVGEFSEAIKAYHRLL 656 EALK N++ E Y L+ +G+F E IKA +++ Sbjct: 369 EALK-NFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVM 412 Score = 31.6 bits (70), Expect = 3.2 Identities = 45/217 (20%), Positives = 85/217 (39%), Gaps = 21/217 (9%) Query: 470 EDVVICYERAGQHGKAEEILRQELEKKETPSLYCLL---GDVLGDHSCYD-KAWELSRYR 525 E++ I Y G E I +E P L + G G +D K EL+ + Sbjct: 145 EELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFE 204 Query: 526 SARA------------QRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLA 573 +R QR++ L L E V +++++ P ++ G Y Sbjct: 205 LSRVITLEPDRPEVFEQRAEILSPLGR--INEAVNDLTKAIQLQP-SARLYRHRGTLYFI 261 Query: 574 LEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWE 633 EDY + + FQ+ + L + A ++ +A + +EALK + ++ Sbjct: 262 SEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYK 321 Query: 634 NYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQVLKI 670 + ++G F A +++ + L L + VQ L++ Sbjct: 322 SLGQAYRELGNFEAATESFQKALLLNQNH--VQTLQL 356 >gi|124256489 crooked neck-like 1 protein [Homo sapiens] Length = 848 Score = 41.2 bits (95), Expect = 0.004 Identities = 31/153 (20%), Positives = 67/153 (43%), Gaps = 3/153 (1%) Query: 505 LGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVW 564 L ++ S Y++A ++ YR+ A + ++N++ ++R++ P W Sbjct: 255 LKEIQRARSIYERALDVD-YRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFW 313 Query: 565 FSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKC 624 + L + G+ + F+R + +P+ +AW++ +R K+ +A RT+ E Sbjct: 314 YKYTYMEEMLGNVAGARQVFERWMEWQPEE-QAWHSYINFELRYKEVDRA-RTIYERFVL 371 Query: 625 NYEHWQIWENYILTSTDVGEFSEAIKAYHRLLD 657 + + W Y F+ A K Y R ++ Sbjct: 372 VHPDVKNWIKYARFEEKHAYFAHARKVYERAVE 404 >gi|4503729 FK506 binding protein 52 [Homo sapiens] Length = 459 Score = 40.8 bits (94), Expect = 0.005 Identities = 41/183 (22%), Positives = 82/183 (44%), Gaps = 19/183 (10%) Query: 435 QVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELE 494 Q+PP+ ++ +L FE S + EKLE I ER + K + + L+ Sbjct: 236 QIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQ---STIVKERGTVYFKEGKYKQALLQ 292 Query: 495 KKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQR-----SKALLHLRNKEFQECVEC 549 K+ S Y+ ++ + A+A R + A+ HL+ + F +E Sbjct: 293 YKKIVSWLE-----------YESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIES 341 Query: 550 FERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLK 609 ++++++ F G A+LA+ D++ + FQ+ + L P+N A L+ R++ Sbjct: 342 CNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIR 401 Query: 610 QKV 612 +++ Sbjct: 402 RQL 404 >gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] Length = 499 Score = 40.0 bits (92), Expect = 0.009 Identities = 20/97 (20%), Positives = 49/97 (50%) Query: 571 YLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQ 630 Y +DY+ + K + + + L P NA + N S +Y+R + A A++ + ++ + Sbjct: 38 YFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 97 Query: 631 IWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQV 667 + ++ +G+F A++ Y ++ ++ KD ++ Sbjct: 98 GYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKM 134 >gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] Length = 2481 Score = 39.7 bits (91), Expect = 0.012 Identities = 48/223 (21%), Positives = 93/223 (41%), Gaps = 39/223 (17%) Query: 500 SLYCLLGDVLGDHSCYDKAWELSRYRS-----ARAQRSKALLHLRNKEFQECVECFERSV 554 ++Y LG CY++ +L + A+ + + + +E + FE+ + Sbjct: 802 AVYMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQL 861 Query: 555 KINPMQLG---------VWFSLGCAYLALEDYQGSAKAFQRCVTLE------PDNAEAWN 599 + G + +LG Y AL DY+ + K +++ +++ D A+A+ Sbjct: 862 AMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYR 921 Query: 600 NLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLR 659 L + +A +LQ+AL C +E ++ + ++GE +AY L L Sbjct: 922 GLGNGH-------RAMGSLQQALVC-------FEKRLVVAHELGEAFNKAQAYGELGSLH 967 Query: 660 DKYKDV-QVLKILVRA--VIDGMTDRS--GDVATGLKGKLQEL 697 + + Q + L R + M DR+ D A GL G Q++ Sbjct: 968 SQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQM 1010 Score = 33.5 bits (75), Expect = 0.85 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 20/96 (20%) Query: 566 SLGCAYLALEDYQGSAKAFQRCVTL------EPDNAEAWNNLSTSYIRLKQKVKAFRTLQ 619 SLG Y A+ DY + + ++CV L E A N+ YI A + Sbjct: 319 SLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYI-------AMGDFE 371 Query: 620 EALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRL 655 A++C+ +H +I + D+G E +AY L Sbjct: 372 NAVQCHEQHLKI-------AKDLGNKREEARAYSNL 400 Score = 30.0 bits (66), Expect = 9.4 Identities = 34/149 (22%), Positives = 65/149 (43%), Gaps = 21/149 (14%) Query: 533 KALLHL-RNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLE 591 KALL+ + +E Q+ + +S+ + + +LG ++ +D G+ K +++ + L Sbjct: 685 KALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLA 744 Query: 592 PD------NAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYE----------HWQIWENY 635 A A+ L T+Y +++ KA + L+ E H + Y Sbjct: 745 HQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVY 804 Query: 636 ILTSTDVGEFSEAIKAYHRLLDLRDKYKD 664 + +G+++ A K Y LDL K KD Sbjct: 805 MA----LGKYTMAFKCYEEQLDLGQKLKD 829 >gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] Length = 313 Score = 39.7 bits (91), Expect = 0.012 Identities = 22/100 (22%), Positives = 53/100 (53%), Gaps = 2/100 (2%) Query: 526 SARAQRSKALLH--LRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKA 583 SA A+R K + ++ + F+ V + +++++NP + + AY L +Y G+ + Sbjct: 88 SAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQD 147 Query: 584 FQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK 623 +R + ++P ++A+ + + L + V+A ++AL+ Sbjct: 148 CERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALE 187 Score = 33.1 bits (74), Expect = 1.1 Identities = 24/97 (24%), Positives = 48/97 (49%), Gaps = 3/97 (3%) Query: 515 YDKAWELSRYRSAR-AQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLA 573 Y KA EL+ + R+ A L N + V+ ER++ I+P + +G A + Sbjct: 114 YGKAIELNPANAVYFCNRAAAYSKLGN--YAGAVQDCERAICIDPAYSKAYGRMGLALSS 171 Query: 574 LEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQ 610 L + + +++ + L+PDN +NL + ++L++ Sbjct: 172 LNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLRE 208 >gi|6912458 calcineurin binding protein 1 [Homo sapiens] Length = 2220 Score = 38.5 bits (88), Expect = 0.026 Identities = 21/95 (22%), Positives = 42/95 (44%) Query: 575 EDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWEN 634 ED + + + + V L+ + W + +RL + A +E L+CN +HW +N Sbjct: 104 EDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDN 163 Query: 635 YILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQVLK 669 I + +++ + + L+ +Y VLK Sbjct: 164 LITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLK 198 Score = 30.0 bits (66), Expect = 9.4 Identities = 20/98 (20%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Query: 531 RSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTL 590 ++ A L + ++ + +E + +V ++ + +W+ +G L L + AF+ + Sbjct: 94 KNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRC 153 Query: 591 EPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALK--CNY 626 PD+ +NL T L + +AL+ C Y Sbjct: 154 NPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRY 191 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.134 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,548,314 Number of Sequences: 37866 Number of extensions: 1257687 Number of successful extensions: 3743 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 74 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 3436 Number of HSP's gapped (non-prelim): 321 length of query: 843 length of database: 18,247,518 effective HSP length: 111 effective length of query: 732 effective length of database: 14,044,392 effective search space: 10280494944 effective search space used: 10280494944 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.