Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 42475558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]
(1137 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens] 2306 0.0
gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens] 2193 0.0
gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens] 2112 0.0
gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor ... 100 8e-21
gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [H... 79 2e-14
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 60 9e-09
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 60 9e-09
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 60 1e-08
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 56 2e-07
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 55 4e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 5e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 53 1e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 53 1e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 53 1e-06
gi|93141033 PAX interacting protein 1 [Homo sapiens] 52 2e-06
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 52 3e-06
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 52 4e-06
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 51 7e-06
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 51 7e-06
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 50 9e-06
gi|50345997 E1A binding protein p300 [Homo sapiens] 50 2e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 50 2e-05
gi|33286444 mastermind-like 2 [Homo sapiens] 50 2e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 50 2e-05
gi|209862789 microtubule associated monoxygenase, calponin and L... 49 2e-05
gi|73808090 zinc finger protein 207 isoform b [Homo sapiens] 49 3e-05
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 49 4e-05
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 49 4e-05
gi|50345881 cytoplasmic polyadenylation element binding protein ... 48 5e-05
gi|146134388 YLP motif containing 1 [Homo sapiens] 48 5e-05
>gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]
Length = 1137
Score = 2306 bits (5976), Expect = 0.0
Identities = 1137/1137 (100%), Positives = 1137/1137 (100%)
Query: 1 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60
MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
Sbjct: 1 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60
Query: 61 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120
WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
Sbjct: 61 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120
Query: 121 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180
VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
Sbjct: 121 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180
Query: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240
LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
Sbjct: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240
Query: 241 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300
KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
Sbjct: 241 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300
Query: 301 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360
NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
Sbjct: 301 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360
Query: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420
LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
Sbjct: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420
Query: 421 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480
LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
Sbjct: 421 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480
Query: 481 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540
GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
Sbjct: 481 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540
Query: 541 EKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTL 600
EKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTL
Sbjct: 541 EKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTL 600
Query: 601 EKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 660
EKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS
Sbjct: 601 EKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 660
Query: 661 RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ 720
RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ
Sbjct: 661 RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ 720
Query: 721 QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 780
QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK
Sbjct: 721 QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 780
Query: 781 SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM 840
SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM
Sbjct: 781 SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM 840
Query: 841 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 900
QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV
Sbjct: 841 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 900
Query: 901 FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 960
FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS
Sbjct: 901 FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 960
Query: 961 SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN 1020
SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN
Sbjct: 961 SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN 1020
Query: 1021 HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1080
HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT
Sbjct: 1021 HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1080
Query: 1081 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH 1137
WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
Sbjct: 1081 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH 1137
>gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]
Length = 1091
Score = 2193 bits (5682), Expect = 0.0
Identities = 1091/1137 (95%), Positives = 1091/1137 (95%), Gaps = 46/1137 (4%)
Query: 1 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60
MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
Sbjct: 1 MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL 60
Query: 61 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120
WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
Sbjct: 61 WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR 120
Query: 121 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180
VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
Sbjct: 121 VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ 180
Query: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240
LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
Sbjct: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240
Query: 241 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300
KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
Sbjct: 241 KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI 300
Query: 301 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360
NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
Sbjct: 301 NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP 360
Query: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420
LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
Sbjct: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE 420
Query: 421 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480
LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
Sbjct: 421 LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV 480
Query: 481 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540
GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
Sbjct: 481 GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG 540
Query: 541 EKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTL 600
EKPVVTFKENIKTREVNRDQGRSFPPKE
Sbjct: 541 EKPVVTFKENIKTREVNRDQGRSFPPKE-------------------------------- 568
Query: 601 EKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 660
VKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS
Sbjct: 569 --------------VKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 614
Query: 661 RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ 720
RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ
Sbjct: 615 RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ 674
Query: 721 QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 780
QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK
Sbjct: 675 QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 734
Query: 781 SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM 840
SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM
Sbjct: 735 SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM 794
Query: 841 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 900
QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV
Sbjct: 795 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 854
Query: 901 FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 960
FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS
Sbjct: 855 FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 914
Query: 961 SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN 1020
SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN
Sbjct: 915 SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN 974
Query: 1021 HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1080
HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT
Sbjct: 975 HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1034
Query: 1081 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH 1137
WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
Sbjct: 1035 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH 1091
>gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]
Length = 1049
Score = 2112 bits (5473), Expect = 0.0
Identities = 1049/1095 (95%), Positives = 1049/1095 (95%), Gaps = 46/1095 (4%)
Query: 43 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 102
MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY
Sbjct: 1 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 60
Query: 103 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 162
TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA
Sbjct: 61 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 120
Query: 163 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 222
RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA
Sbjct: 121 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 180
Query: 223 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 282
STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR
Sbjct: 181 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 240
Query: 283 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 342
LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL
Sbjct: 241 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 300
Query: 343 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 402
CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP
Sbjct: 301 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 360
Query: 403 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 462
HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI
Sbjct: 361 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 420
Query: 463 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 522
GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG
Sbjct: 421 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 480
Query: 523 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKN 582
LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKE
Sbjct: 481 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKE-------------- 526
Query: 583 DGKKDNNKRKTETKKCTLEKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQAS 642
VKSQTELRKTPVSEARKTPVTQTPTQAS
Sbjct: 527 --------------------------------VKSQTELRKTPVSEARKTPVTQTPTQAS 554
Query: 643 NSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS 702
NSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS
Sbjct: 555 NSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS 614
Query: 703 PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 762
PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ
Sbjct: 615 PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 674
Query: 763 ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 822
ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL
Sbjct: 675 ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 734
Query: 823 QTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRS 882
QTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRS
Sbjct: 735 QTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRS 794
Query: 883 VMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQE 942
VMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQE
Sbjct: 795 VMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQE 854
Query: 943 RYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQ 1002
RYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQ
Sbjct: 855 RYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQ 914
Query: 1003 SPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLS 1062
SPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLS
Sbjct: 915 SPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLS 974
Query: 1063 ATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQ 1122
ATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQ
Sbjct: 975 ATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQ 1034
Query: 1123 KQKQQRGQGTMNPPH 1137
KQKQQRGQGTMNPPH
Sbjct: 1035 KQKQQRGQGTMNPPH 1049
>gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor
[Homo sapiens]
Length = 1419
Score = 100 bits (249), Expect = 8e-21
Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 16/243 (6%)
Query: 7 QYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFK 66
Q L+ + +L D + G ++ R L LY++ ++ D+E++ ++ V+Q LW +AF
Sbjct: 591 QELQLSNLLSRDRISPE-GLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFY 649
Query: 67 NQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQL 126
I + K+ N +++ L L+ S F+ LLQ+L + L + +
Sbjct: 650 QVIEKFRQLVKDPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYMDGLAI 709
Query: 127 GIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTS------QAESYYRHAAQ 180
++T A++ Q C++ GDIARYR Q S +A S+Y A
Sbjct: 710 RSKPLRKTVKYALIS---------AQRCMICQGDIARYREQASDTANYGKARSWYLKAQH 760
Query: 181 LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV 240
+ P NG+PYNQLA+LA L ++YY RS+A P A +L + +++
Sbjct: 761 IAPKNGRPYNQLALLAVYTRRKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQM 820
Query: 241 KTK 243
+ K
Sbjct: 821 EKK 823
Score = 36.6 bits (83), Expect = 0.14
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 29/147 (19%)
Query: 249 FIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLL--FQKAFNSQQLVHVTVINLFQLH 306
FI +F+ HG ++ +E + EK+ ++F+ LL S +++ + IN+F +H
Sbjct: 892 FILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVH 951
Query: 307 H--LRD-FSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPL-------------QNE 350
+ L+D FS E Q L LA+F S L C C L Q++
Sbjct: 952 NSQLKDCFSEECRSVIQEQAAALG----LAMF-SLLVRRCTCLLKESAKAQLSSPEDQDD 1006
Query: 351 SQEESYNAYP------LPAVKVSMDWL 371
+ +++ LP+VKV DW+
Sbjct: 1007 QDDIKVSSFVPDLKELLPSVKVWSDWM 1033
>gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [Homo
sapiens]
Length = 1016
Score = 79.0 bits (193), Expect = 2e-14
Identities = 62/225 (27%), Positives = 106/225 (47%), Gaps = 29/225 (12%)
Query: 33 RQALQDLYQK-MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANL 91
R L++L K M + ++Y +K E+ LW + I ++ K+ + RS ++
Sbjct: 56 RNKLRELCVKLMFLHPVDYG--RKAEELLWRKVYYEVIQLIKTNKKHIHS--RSTLECAY 111
Query: 92 SLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIV---KPQSSS-- 146
L A GFY LL + + + ++L C + + + T ++ KP S+S
Sbjct: 112 RTHLVAGIGFYQHLLLYIQSHYQLELQCCIDWTHV---------TDPLIGCKKPVSASGK 162
Query: 147 ----CSYICQHCLVHLGDIARYRNQTSQ------AESYYRHAAQLVPSNGQPYNQLAILA 196
C CLV+LGD++RY+N+ + AE +Y A + P G P+NQL LA
Sbjct: 163 EMDWAQMACHRCLVYLGDLSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLA 222
Query: 197 SSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVK 241
SK ++ ++ Y R I + F A NL++ KA + ++K
Sbjct: 223 GSKYYNVEAMYCYLRCIQSEVSFEGAYGNLKRLYDKAAKMYHQLK 267
Score = 41.6 bits (96), Expect = 0.004
Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 24/168 (14%)
Query: 361 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLN-------------SFHPHEEDL 407
LPAVKV +DWLR P + Q +W L LLN + P +DL
Sbjct: 655 LPAVKVFLDWLRTNPDLI-IVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDL 713
Query: 408 SSISATP-------LPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLI 460
P LPE+ L+ LR + R +F ++ +E +R +
Sbjct: 714 LEGCELPDLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESV---VRICCIR 770
Query: 461 SIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQE 508
S G +IA Q ++Q EVG + I + + L ++A+ + +E
Sbjct: 771 SFGHFIARLQGSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEE 818
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 60.5 bits (145), Expect = 9e-09
Identities = 115/475 (24%), Positives = 159/475 (33%), Gaps = 85/475 (17%)
Query: 633 PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF-PAGVSV 691
P+ +TP +S P+ G P P G P + PP G GY P G
Sbjct: 373 PLARTPQPSS-----PMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQT 426
Query: 692 PGTF---LQPTAHSPAGNQVQAGKQSHIPYSQQRPSG--------------PGPMNQGPQ 734
P + +Q A S G Q PY QQ PSG P P Q P
Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYT--QQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484
Query: 735 QS-QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQ 793
S QPPSQ P AQP+ Q Q Q L Q Q P P+ PPH Y
Sbjct: 485 YSQQPPSQTP----HAQPSYQQQPQSQPPQL-QSSQPPYSQQPS---QPPHQQSPAPYPS 536
Query: 794 ADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFP 853
++ Q P QP Y Q P Q P QQQP + P
Sbjct: 537 QQSTTQQ-------------HPQSQPPYSQ---------PQAQSPYQQQQPQQ------P 568
Query: 854 MEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPF 913
+ P+ + + R Q+ + D G ++ P M
Sbjct: 569 APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA--------SSAPSMTS 620
Query: 914 EKSLLEKPS-ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAP 972
K E + L S SS L+G + ++ V ++SS + +P+ +P
Sbjct: 621 SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680
Query: 973 ----QETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV--PF 1026
L + +P PAS S SP + + +P PP+ +S+ P
Sbjct: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740
Query: 1027 SNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTW 1081
N I +R + P G SA S + S Q T G++
Sbjct: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPG-------SALSPRQPSGGQIHTGMGSY 788
Score = 36.2 bits (82), Expect = 0.18
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 19/121 (15%)
Query: 638 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPAGVSVPGTF 695
P Q S+ P H ++ P+R +PPP Y + P + GSG AG P
Sbjct: 198 PQQNSHDHGFPNHQYNSY--YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP--- 252
Query: 696 LQPTAHSPAGNQVQAGKQSHIPYSQQR---PSGPGPMNQGPQQSQPPSQQPLTSLPAQPT 752
P++ + A + S ++QQR G GP G QP + L L P+
Sbjct: 253 --PSSSASASS-------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPS 303
Query: 753 A 753
+
Sbjct: 304 S 304
Score = 31.6 bits (70), Expect = 4.5
Identities = 37/186 (19%), Positives = 64/186 (34%), Gaps = 21/186 (11%)
Query: 688 GVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSL 747
G + P T T PAG G Q+ P+ R P QQ+ PP
Sbjct: 1432 GNAYPATATAATERRPAG-----GPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQ 1486
Query: 748 PAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQL-----W- 801
+ AQ + Q + + ++ + + P +H + + ++ W
Sbjct: 1487 ASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWP 1546
Query: 802 -----NPPQVQGPLGKIMPVKQPYYLQTQDPIKLFE--PSLQPPVMQQQPLEKKMKPFPM 854
PP GP + P+ +P Q P + P + P +P+E + P
Sbjct: 1547 SHGTRQPP--YGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSP-SK 1603
Query: 855 EPYNHN 860
P+ H+
Sbjct: 1604 SPFLHS 1609
Score = 31.2 bits (69), Expect = 5.9
Identities = 48/226 (21%), Positives = 79/226 (34%), Gaps = 20/226 (8%)
Query: 717 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 776
PYS+ G G + GP+Q P P + +P + A Q P+
Sbjct: 1259 PYSRAAGPGLGNVAMGPRQHYPYG-GPYDRVRTEPGIGPEGNMSTGA-PQPNLMPSNPDS 1316
Query: 777 ALGKSPPHHSGFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQP--YYLQTQDPIKLFEP 833
+ SP + QQ QQ N QG P G P +Q Y Q Q+ + +
Sbjct: 1317 GM-YSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDG 1375
Query: 834 SLQPPVM--------------QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMAD 879
+ PP Q QP ++++ P +P + + P+ + Y A
Sbjct: 1376 TYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAY 1435
Query: 880 NRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELM 925
+ A G ++ F+ +D V P + P ++M
Sbjct: 1436 PATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMM 1481
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 60.5 bits (145), Expect = 9e-09
Identities = 115/475 (24%), Positives = 159/475 (33%), Gaps = 85/475 (17%)
Query: 633 PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF-PAGVSV 691
P+ +TP +S P+ G P P G P + PP G GY P G
Sbjct: 373 PLARTPQPSS-----PMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQT 426
Query: 692 PGTF---LQPTAHSPAGNQVQAGKQSHIPYSQQRPSG--------------PGPMNQGPQ 734
P + +Q A S G Q PY QQ PSG P P Q P
Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYT--QQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484
Query: 735 QS-QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQ 793
S QPPSQ P AQP+ Q Q Q L Q Q P P+ PPH Y
Sbjct: 485 YSQQPPSQTP----HAQPSYQQQPQSQPPQL-QSSQPPYSQQPS---QPPHQQSPAPYPS 536
Query: 794 ADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFP 853
++ Q P QP Y Q P Q P QQQP + P
Sbjct: 537 QQSTTQQ-------------HPQSQPPYSQ---------PQAQSPYQQQQPQQ------P 568
Query: 854 MEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPF 913
+ P+ + + R Q+ + D G ++ P M
Sbjct: 569 APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA--------SSAPSMTS 620
Query: 914 EKSLLEKPS-ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAP 972
K E + L S SS L+G + ++ V ++SS + +P+ +P
Sbjct: 621 SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680
Query: 973 ----QETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV--PF 1026
L + +P PAS S SP + + +P PP+ +S+ P
Sbjct: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740
Query: 1027 SNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTW 1081
N I +R + P G SA S + S Q T G++
Sbjct: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPG-------SALSPRQPSGGQIHTGMGSY 788
Score = 36.2 bits (82), Expect = 0.18
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 19/121 (15%)
Query: 638 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPAGVSVPGTF 695
P Q S+ P H ++ P+R +PPP Y + P + GSG AG P
Sbjct: 198 PQQNSHDHGFPNHQYNSY--YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP--- 252
Query: 696 LQPTAHSPAGNQVQAGKQSHIPYSQQR---PSGPGPMNQGPQQSQPPSQQPLTSLPAQPT 752
P++ + A + S ++QQR G GP G QP + L L P+
Sbjct: 253 --PSSSASASS-------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPS 303
Query: 753 A 753
+
Sbjct: 304 S 304
Score = 33.1 bits (74), Expect = 1.5
Identities = 46/199 (23%), Positives = 73/199 (36%), Gaps = 16/199 (8%)
Query: 717 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 776
PYS+ G G + GP+Q P P + +P + A Q P+
Sbjct: 1259 PYSRAAGPGLGNVAMGPRQHYPYG-GPYDRVRTEPGIGPEGNMSTGA-PQPNLMPSNPDS 1316
Query: 777 ALGKSPPHHSGFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQPYYLQTQDPIKLFEPSL 835
+ SP + QQ QQ N QG P G P +Q Q Q + P
Sbjct: 1317 GM-YSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLP 1375
Query: 836 QPPVMQQQPLE--------KKMKPFPMEPYNH-NPSEVKVPEFYWDSSY---SMADNRSV 883
+P + P + K K P P +H P+ V+ P D ++ S+ + V
Sbjct: 1376 RPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPV 1435
Query: 884 MAQQANIDRRGKRSPGVFR 902
+ Q+ + + +P +R
Sbjct: 1436 LKQRRRLTMKDIGTPEAWR 1454
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 60.1 bits (144), Expect = 1e-08
Identities = 93/385 (24%), Positives = 144/385 (37%), Gaps = 58/385 (15%)
Query: 672 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 731
PPP M + P T LQ A Q Q +Q + QQ+ + Q
Sbjct: 129 PPPGTSGMAPHSMAVVSTATPQTQLQ--LQQVALQQQQQQQQ----FQQQQQAALQQQQQ 182
Query: 732 GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQY 791
QQ Q +QQ Q Q QLQ Q QQQQ K HH QQ
Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQ--QQQQQHLIKL---------HHQNQQQI 231
Query: 792 QQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 851
QQ +QL Q+Q L + +Q Q Q ++ P QPP+ Q QP + P
Sbjct: 232 QQ--QQQQLQRIAQLQ--LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287
Query: 852 FPMEPYNHNPSEVKVPEFYWDSSYSMADNR----SVMAQQANIDRRGKRSPGVFRPEQDP 907
++ +H P+ +A N+ +Q + + + PG Q P
Sbjct: 288 QQLQQMHHTQHHQPPPQ---PQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP 344
Query: 908 ---------VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNL 958
V + P + + ++ + + + ++ + G ++Q P + + G+ +
Sbjct: 345 LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLP--MLSSPSPGQQV 402
Query: 959 TSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS--SNPSSLPSSP 1016
+ P +PQ P PS +S+ S+ + SP S +PS PS
Sbjct: 403 QTPQSMPPPPQPSPQ-----------PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS 451
Query: 1017 P----THNHNSVPFSNFGPIGTPDN 1037
P T + SVP + GP+ TP N
Sbjct: 452 PVTARTPQNFSVP--SPGPLNTPVN 474
Score = 38.5 bits (88), Expect = 0.037
Identities = 63/264 (23%), Positives = 95/264 (35%), Gaps = 39/264 (14%)
Query: 601 EKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLP- 659
++ Q+ +Q +++Q +++ P+ + + P P Q H P P P
Sbjct: 250 QQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPP 309
Query: 660 ---SRPGFPPPTYVIPPPVAFSMGSG----YTFP--AGVSVPGTFLQPTAH--------- 701
++P PP P V+ + YT P V P QP
Sbjct: 310 VAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTA 369
Query: 702 ---SPAGNQVQAG---KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQS 755
+ A V G QS +P PS PG Q P QS PP QP + P QP++Q
Sbjct: 370 VQTAQAAQMVAPGVQVSQSSLPMLSS-PS-PGQQVQTP-QSMPPPPQP-SPQPGQPSSQP 425
Query: 756 TSQLQVQALTQQQQSPTKAVPALGKSP---PHHSGFQQYQQADASKQL---WNPPQVQGP 809
S + + SP+ +P+ P P + Q + L NP V P
Sbjct: 426 NSNVS----SGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSP 481
Query: 810 LGKIMPVKQPYYLQTQDPIKLFEP 833
G +Q Y + + K EP
Sbjct: 482 AGSSQAEEQQYLDKLKQLSKYIEP 505
Score = 33.1 bits (74), Expect = 1.5
Identities = 46/221 (20%), Positives = 78/221 (35%), Gaps = 12/221 (5%)
Query: 615 VKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPP 674
V+ Q + ++T V A+ + Q S S + P + + PPP P P
Sbjct: 359 VQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQP 418
Query: 675 VAFSMGSGYTFPAG-VSVPGTFLQPTAHSPAGNQVQAGKQSHI----PYSQQRPSGPGPM 729
S +G P +FL + P+ + V A + P P P +
Sbjct: 419 GQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSV 478
Query: 730 NQGPQQSQPPSQQPLTSLP-----AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPH 784
SQ QQ L L +P + +++ ++ S K++ + P
Sbjct: 479 MSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSK 538
Query: 785 HSGFQQYQQAD-ASKQLWNPPQV-QGPLGKIMPVKQPYYLQ 823
+ Q+ + A ++L N V P + P KQ Y Q
Sbjct: 539 RCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQ 579
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 55.8 bits (133), Expect = 2e-07
Identities = 119/453 (26%), Positives = 159/453 (35%), Gaps = 84/453 (18%)
Query: 645 QFIPIHHPGAFPPLPSRPGFPPP----TYVIPPPVAFSMGSGYTFPAGVSVPGTF----- 695
Q P P PP P +P PPP PPP SM PA S P F
Sbjct: 747 QQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQ-QAAPAMKSSPPPFIATQV 805
Query: 696 --LQP----TAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPP--SQQPLTSL 747
L+P + P G+ Q H+P +P P + Q P+ S PP +Q + S
Sbjct: 806 PVLEPQLPGSVFDPIGHFTQ--PILHLP----QPELPPHLPQPPEHSTPPHLNQHAVVSP 859
Query: 748 P----AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSP--PHHSGFQQYQQADASKQLW 801
P A P S + AL + P PAL ++P P Q Q ++
Sbjct: 860 PALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPP 919
Query: 802 NPP----QVQGPLGKIMPVKQPYYL------QTQDPIKL---FEPSLQPPVMQQQPLEKK 848
PP Q+Q L ++ V+ P L Q+Q P L PS+Q + QQ P
Sbjct: 920 APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPP 979
Query: 849 MKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPV 908
+P P H P V S + QQ G++ P P Q
Sbjct: 980 PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPP----PPQPAK 1035
Query: 909 PRMPFEK---------------SLLEKPSELMSHS---SSFLSLTGFSLNQERYPNNSMF 950
P+ + L E PS LM HS S F SLT S Q+
Sbjct: 1036 PQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKK-- 1093
Query: 951 NEVYGKNLTSSSKAELSPSMAPQETSLYS-LFEGTPWSPSLPASSDHSTPASQSPHSSNP 1009
+ L ++S + P + +E ++S + P+SPSL P P
Sbjct: 1094 -----QELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL-----RPEPPKHPESIKAP 1143
Query: 1010 SSLPSSP---PTHNHNSV---PFSNFGPIGTPD 1036
LP P P V P N P G PD
Sbjct: 1144 VHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPD 1176
Score = 41.6 bits (96), Expect = 0.004
Identities = 64/286 (22%), Positives = 92/286 (32%), Gaps = 64/286 (22%)
Query: 636 QTPTQASNSQFI----PIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSV 691
Q P++ SN P P P L P P P PP V P
Sbjct: 868 QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQ 927
Query: 692 PGTFLQ-------PTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPL 744
+LQ PT P+ +VQ+ +P PS + Q P PP QP
Sbjct: 928 MQLYLQQLQKVQPPTPLLPS-VKVQSQPPPPLP-PPPHPSVQQQLQQQPPPPPPPQPQPP 985
Query: 745 TSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQ-------------- 790
QP + +Q T QQ P P G+ PPH QQ
Sbjct: 986 PQQQHQPPPRPVHLQPMQFSTHIQQPP----PPQGQQPPHPPPGQQPPPPQPAKPQQVIQ 1041
Query: 791 -----------------YQQADASKQLWNPPQVQ--------GPLGKIMPVKQPY----Y 821
++A + + +P Q P + P KQ
Sbjct: 1042 HHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASV 1101
Query: 822 LQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVP 867
+Q Q + + E + P+++ +P ++P EP H P +K P
Sbjct: 1102 VQPQPLVVVKEEKIHSPIIRSEPFSPSLRP---EPPKH-PESIKAP 1143
Score = 40.4 bits (93), Expect = 0.010
Identities = 44/140 (31%), Positives = 55/140 (39%), Gaps = 25/140 (17%)
Query: 705 GNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQAL 764
G+ + K+ H + QQ P P+ PQQ PP QQP P P Q Q Q
Sbjct: 729 GHPGREQKKHHHHHHQQMQQAPAPV---PQQPPPPPQQP----PPPPPPQ--QQQQPPPP 779
Query: 765 TQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQT 824
P +A PA+ SPP F Q QL P V P+G T
Sbjct: 780 PPPPSMPQQAAPAMKSSPP---PFIATQVPVLEPQL--PGSVFDPIGHF----------T 824
Query: 825 QDPIKLFEPSLQPPVMQQQP 844
Q + L +P L PP + Q P
Sbjct: 825 QPILHLPQPEL-PPHLPQPP 843
Score = 33.5 bits (75), Expect = 1.2
Identities = 59/279 (21%), Positives = 100/279 (35%), Gaps = 45/279 (16%)
Query: 601 EKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 660
+K ++ K+ + K + E+ + S+A++ P +T S++ + P P+ S
Sbjct: 537 KKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPA---PMKS 593
Query: 661 RPGFPPPTYVIPP-----PVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQS- 714
+P PPTY P+++ + +PG L H + +
Sbjct: 594 KP---PPTYESEEEDKCKPMSYEEKRQLSLDIN-KLPGEKLGRVVHIIQSREPSLKNSNP 649
Query: 715 ---HIPYSQQRPSGPGPMNQGPQQSQPPSQQP----------------LTSLPAQPTAQS 755
I + +PS + + ++P +S ++ +++S
Sbjct: 650 DEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSES 709
Query: 756 TSQLQVQALTQQQ-QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIM 814
+S + T+ +S K P + HH QQ QQA A PP Q P
Sbjct: 710 SSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQP----- 764
Query: 815 PVKQPYYLQTQDPIKLFEPSLQPPVMQQQ--PLEKKMKP 851
P P Q Q P P PP M QQ P K P
Sbjct: 765 PPPPPPQQQQQPP-----PPPPPPSMPQQAAPAMKSSPP 798
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
sapiens]
Length = 2191
Score = 55.1 bits (131), Expect = 4e-07
Identities = 130/536 (24%), Positives = 191/536 (35%), Gaps = 88/536 (16%)
Query: 653 GAFPPLPSRPGFPPPTYVIPPPVAFSMGS---GYTFPAGVSVPGTF-LQPTAHSPAGNQV 708
G++P S P PPP P A + G+ G AG+ + Q A SPA
Sbjct: 377 GSYPEYSS-PSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAA 435
Query: 709 QAGKQSHIPYSQQRPSGPGPM---NQGPQQSQPPSQQP-LTSLPAQPTAQSTSQLQVQAL 764
Q ++SH S P PGP +QG ++P L + + P +Q
Sbjct: 436 Q--QRSHPAMS---PGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG 490
Query: 765 TQQQQSPTK-AVPALGKSPPHHSGFQQYQQADASKQLWN------PPQV--QGPLGKIMP 815
+ P + + G++P +G Q QQ D+ W PPQ QG G
Sbjct: 491 SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQ 550
Query: 816 VKQPYYLQTQDPIKL-----FEPS-----LQPPV-MQQQPLEKKMKPFPMEPYNHNPSEV 864
+QPYY Q P L + PS QP M Q+ + +P P+ P N ++
Sbjct: 551 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP-PLAPGKPNHEDL 609
Query: 865 KV-----PEFYWDSSYSMAD---------NRSVMAQQANIDRRGKRSP--GVFRPEQDP- 907
+ P D S S+ D + +V A + + + +P F P P
Sbjct: 610 NLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPH 669
Query: 908 ---VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKA 964
+P P PS + S S S +G ++ P + M + G SSS
Sbjct: 670 LSSIPGGP-------SPSPVGSPVGSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHP 721
Query: 965 ELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV 1024
LS S PQE + GT +P + T S SPH S P + + S
Sbjct: 722 ALSQSPMPQERGFMA---GTQRNPQMAQYGPQQTGPSMSPHPS-PGGQMHAGISSFQQSN 777
Query: 1025 PFSNFGP----IGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 1080
+GP G N R PA G + + S S + +
Sbjct: 778 SSGTYGPQMSQYGPQGNYSR---------PPAYSG-----VPSASYSGPGPGMGISANNQ 823
Query: 1081 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPP 1136
G GPS + AV + + S + P P + + Q+G M PP
Sbjct: 824 MHGQGPS-QPCGAVPLGRMPS--AGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP 876
Score = 40.0 bits (92), Expect = 0.013
Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 9/124 (7%)
Query: 652 PGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAG 711
P A P L S PG P P+ V P + SG PA S+PG+ + P P G+Q ++
Sbjct: 664 PHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPA--SIPGSQMPP---QPPGSQSESS 718
Query: 712 KQ---SHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQ 768
S P Q+R G + PQ +Q QQ S+ P+ + + Q
Sbjct: 719 SHPALSQSPMPQERGFMAG-TQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSN 777
Query: 769 QSPT 772
S T
Sbjct: 778 SSGT 781
Score = 36.2 bits (82), Expect = 0.18
Identities = 46/165 (27%), Positives = 59/165 (35%), Gaps = 18/165 (10%)
Query: 622 RKTPVSEARKTPVTQTPTQASNSQFIPIHHPG-AFPPLPSRPGFPPPTYVIPPPVAFSMG 680
R P+S A P +Q P Q SQ HP + P+P GF T P +
Sbjct: 692 RSGPISPA-SIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQY--- 747
Query: 681 SGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQ--QSQP 738
G G + P H G Q+ AG S + GP GPQ S+P
Sbjct: 748 -------GPQQTGPSMSP--HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRP 798
Query: 739 PSQQPLTSLP-AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSP 782
P+ + S + P Q Q P AVP LG+ P
Sbjct: 799 PAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVP-LGRMP 842
Score = 33.1 bits (74), Expect = 1.5
Identities = 52/225 (23%), Positives = 72/225 (32%), Gaps = 39/225 (17%)
Query: 650 HHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ 709
H PG +P P+ Y PP G Y + Q ++
Sbjct: 1303 HQPGLYPQQPNYKRHMDGMY--GPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP 1360
Query: 710 AGKQSHIPYSQQRPSGPGPMNQ---GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 766
Q PYS++R GPG + PQ P Q + P Q + + + +
Sbjct: 1361 IQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNR 1420
Query: 767 Q-QQSPTKAVPALGKS------------------PPHHSGFQQYQQADASKQ-LWNPPQV 806
Q PT+A P G + P H S Q Y + AS Q + PP
Sbjct: 1421 QGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPP-- 1478
Query: 807 QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 851
QP Y QT + P Q+ LE +M P
Sbjct: 1479 -----------QPSY-QTPPSLPNHISRAPSPASFQRSLENRMSP 1511
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 54.7 bits (130), Expect = 5e-07
Identities = 123/483 (25%), Positives = 175/483 (36%), Gaps = 86/483 (17%)
Query: 593 TETKKCTLEKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQT-PTQASNSQFIPIHH 651
T +K L +A S T+ R P + TP+ T P + +P+
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
Query: 652 PGAFPP-----LPSRPGFPP----PTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS 702
P P LPS P PP P+ PP A S T P + VP + P+ +
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA--PPSLQTIPP-IQVPHSLTSPSLQA 402
Query: 703 P----AGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQ----------------PPSQQ 742
P A + +QA P Q S + P+Q+Q PP Q
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSF---LTMSPRQTQASLTSPSRPASTPPDSPPLQA 459
Query: 743 PLTSLPAQPTAQSTSQLQVQALTQQQQ-SPTKAVPALGKSPPHHSGFQQYQQADASKQLW 801
PL SLPA P Q++ V L+ P +A+ +L P QA S +
Sbjct: 460 PL-SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP---------QAPLSSLIM 509
Query: 802 NPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQP-------LEKKMKPFPM 854
P + Q L P L T L PSL PP +Q LE P P
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENL--PSLAPPPLQTASAPLTTPHLETPPCPAPC 567
Query: 855 EPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFE 914
P PS + P SS + ++ A A+ +G SP + P P P+ P
Sbjct: 568 -PLQAPPSPLTTPPPETPSSIATPPPQAPPAL-ASPPLQGLPSPPL-SPLATPPPQAPPX 624
Query: 915 KSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQE 974
+L P + + L+ + + PN + + +A SP +P
Sbjct: 625 LAL--PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL---------QAPFSPPPSPPV 673
Query: 975 TSLYSLFEGTPWSPSLPASSDHSTPASQSPHS--SNPSSLPSSPPTHNHNSVPFSNFGPI 1032
+ +S P+ P S +TP SQ+P S + P +P SPP S P S P
Sbjct: 674 QAPFS-------PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA----SPPMS---PS 719
Query: 1033 GTP 1035
TP
Sbjct: 720 ATP 722
Score = 43.1 bits (100), Expect = 0.001
Identities = 83/378 (21%), Positives = 127/378 (33%), Gaps = 61/378 (16%)
Query: 674 PVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGP 733
P ++ +G PGT A + G P ++ RP GP
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210
Query: 734 QQSQPPSQQPLTSLPAQPTA----QSTSQLQVQALTQQQQSPTKAVPALGKSP--PHHSG 787
S+ + +P + +P+A Q + + + SP ++ P+ +P P H
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270
Query: 788 FQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYY---LQTQDPIKLFEPSLQPPVMQQQP 844
Q Q PPQV P P P L T P + PP P
Sbjct: 271 ----QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP 326
Query: 845 LEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPE 904
L + P P P +P + + A + SP P
Sbjct: 327 LPATLPPSP-------PLATPLP-------------LAPPSPSAPPSLQTLPSPPATPPS 366
Query: 905 QDP----VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 960
Q P P M SL P + HS + SL + P+ + +
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL-------QAPPSPLALSSLQATTSLG 419
Query: 961 SSKAELSPS---MAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPP 1017
S + + S M+P++T + + SPS PAS+ +P Q+ P SLP+SPP
Sbjct: 420 SPTLQATHSFLTMSPRQT------QASLTSPSRPASTPPDSPPLQA-----PLSLPASPP 468
Query: 1018 THNHNSVPFSNFGPIGTP 1035
S S P+ +P
Sbjct: 469 LQTSLSPAVS---PLSSP 483
Score = 35.4 bits (80), Expect = 0.31
Identities = 65/245 (26%), Positives = 86/245 (35%), Gaps = 39/245 (15%)
Query: 623 KTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPP------PVA 676
+TP S A TP Q P ++ + P PL + P PP +PP P A
Sbjct: 582 ETPSSIA--TPPPQAPPALASPPLQGLPSP-PLSPLATPPPQAPPXLALPPLQAPPSPPA 638
Query: 677 FSMGSGYTFP---AGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQR-----PSGPGP 728
S P A ++ LQ P VQA P+S PS P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA------PFSPPASPPVSPSATPP 692
Query: 729 MNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGF 788
P + PP Q P S PA P ++ QA P + P+ SPP
Sbjct: 693 SQAPPSLAAPPLQVP-PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP----- 746
Query: 789 QQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIK-LFEPSLQ-PPVMQQQPLE 846
S PP+V PL P++ P P+ L +P Q PP + PL+
Sbjct: 747 -------MSPSATPPPRVP-PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798
Query: 847 KKMKP 851
P
Sbjct: 799 ALPSP 803
Score = 35.4 bits (80), Expect = 0.31
Identities = 36/142 (25%), Positives = 47/142 (33%), Gaps = 11/142 (7%)
Query: 625 PVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFP--------PPTYVIPPPVA 676
P+S + P P A+ +P P + P PS P PP V P P A
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
Query: 677 FSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQS 736
S P + P P P+ A P+S P+ P Q+
Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSP---PASFPGQAPFSPSASLPMSPLATPPPQA 831
Query: 737 QPPSQQPLTSLPAQPTAQSTSQ 758
P PL +P P A T Q
Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQ 853
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 53.1 bits (126), Expect = 1e-06
Identities = 73/275 (26%), Positives = 94/275 (34%), Gaps = 58/275 (21%)
Query: 627 SEARKTPVTQT-PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF 685
S+A P T P ++ Q P HP PP P P P P PP+ GS
Sbjct: 228 SQAPNQPQAPTAPVPHTHIQQAPALHPQR-PPSPHPPPHPSPH----PPLQPLTGS---- 278
Query: 686 PAGVSVPGTFLQPTAHS---PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQ 742
AG + QP H P + +QAG Q P P P PQ SQ Q
Sbjct: 279 -AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL------QHPGPPQPFGLPPQASQ--GQA 329
Query: 743 PLTSLPAQPTAQSTSQLQV-QALTQQQQSP-------------------TKAVPALG--- 779
PL + PA ++ QL Q+ Q QQ P T +P L
Sbjct: 330 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 389
Query: 780 --KSPPHHSGFQQYQQAD-----------ASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD 826
K PPH SG + +S +PP P ++MP QP
Sbjct: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 449
Query: 827 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNP 861
P L + PP P + P P+ +P
Sbjct: 450 PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHP 484
Score = 52.8 bits (125), Expect = 2e-06
Identities = 114/520 (21%), Positives = 167/520 (32%), Gaps = 120/520 (23%)
Query: 518 DGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGI 577
+ S LKS ++++ + ++ T + KT+E++R P E + S
Sbjct: 85 EASSPLKSNKRQREKVASDTEEADR---TSSKKTKTQEISRPNS----PSEGEGESSDSR 137
Query: 578 TVTKNDGKKDNNKRKTETKKCTLEKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQT 637
+V ++G D + + + ++ + Q L+ P + T VT
Sbjct: 138 SVN-DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA 196
Query: 638 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQ 697
P+ A P P LP+ PG P +PP GS P P
Sbjct: 197 PSSA----------PPGTPQLPT-PGPTPSATAVPP-----QGS----PTASQAPNQPQA 236
Query: 698 PTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTS 757
PTA P +Q H QRP P P P S P QPLT QP+A S +
Sbjct: 237 PTAPVPH-THIQQAPALH----PQRPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHA 288
Query: 758 QLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQ---YQQADASKQLWNPPQV---QGPLG 811
Q P G+ PP Q Q + PPQ Q PLG
Sbjct: 289 Q----------------PPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 332
Query: 812 KIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYW 871
P+ T + + +LQ QQ P E+ + P P+
Sbjct: 333 TSPAAAYPH---TSLQLPASQSALQS---QQPPREQPLPPAPLA---------------- 370
Query: 872 DSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSF 931
P + P P+P++P ++ H
Sbjct: 371 -------------------------MPHIKPPPTTPIPQLPAPQA--------HKHPPHL 397
Query: 932 LSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLP 991
+ FS+N P ++ K L+S S PS P L + P SP+ P
Sbjct: 398 SGPSPFSMNANLPPPPAL------KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQP 450
Query: 992 ASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGP 1031
S P S P+ L P PF GP
Sbjct: 451 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 490
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 53.1 bits (126), Expect = 1e-06
Identities = 73/275 (26%), Positives = 94/275 (34%), Gaps = 58/275 (21%)
Query: 627 SEARKTPVTQT-PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF 685
S+A P T P ++ Q P HP PP P P P P PP+ GS
Sbjct: 782 SQAPNQPQAPTAPVPHTHIQQAPALHPQR-PPSPHPPPHPSPH----PPLQPLTGS---- 832
Query: 686 PAGVSVPGTFLQPTAHS---PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQ 742
AG + QP H P + +QAG Q P P P PQ SQ Q
Sbjct: 833 -AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL------QHPGPPQPFGLPPQASQ--GQA 883
Query: 743 PLTSLPAQPTAQSTSQLQV-QALTQQQQSP-------------------TKAVPALG--- 779
PL + PA ++ QL Q+ Q QQ P T +P L
Sbjct: 884 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 943
Query: 780 --KSPPHHSGFQQYQQAD-----------ASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD 826
K PPH SG + +S +PP P ++MP QP
Sbjct: 944 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 1003
Query: 827 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNP 861
P L + PP P + P P+ +P
Sbjct: 1004 PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHP 1038
Score = 52.8 bits (125), Expect = 2e-06
Identities = 114/520 (21%), Positives = 167/520 (32%), Gaps = 120/520 (23%)
Query: 518 DGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGI 577
+ S LKS ++++ + ++ T + KT+E++R P E + S
Sbjct: 639 EASSPLKSNKRQREKVASDTEEADR---TSSKKTKTQEISRPNS----PSEGEGESSDSR 691
Query: 578 TVTKNDGKKDNNKRKTETKKCTLEKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQT 637
+V ++G D + + + ++ + Q L+ P + T VT
Sbjct: 692 SVN-DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA 750
Query: 638 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQ 697
P+ A P P LP+ PG P +PP GS P P
Sbjct: 751 PSSA----------PPGTPQLPT-PGPTPSATAVPP-----QGS----PTASQAPNQPQA 790
Query: 698 PTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTS 757
PTA P +Q H QRP P P P S P QPLT QP+A S +
Sbjct: 791 PTAPVPH-THIQQAPALH----PQRPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHA 842
Query: 758 QLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQ---YQQADASKQLWNPPQV---QGPLG 811
Q P G+ PP Q Q + PPQ Q PLG
Sbjct: 843 Q----------------PPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 886
Query: 812 KIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYW 871
P+ T + + +LQ QQ P E+ + P P+
Sbjct: 887 TSPAAAYPH---TSLQLPASQSALQS---QQPPREQPLPPAPLA---------------- 924
Query: 872 DSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSF 931
P + P P+P++P ++ H
Sbjct: 925 -------------------------MPHIKPPPTTPIPQLPAPQA--------HKHPPHL 951
Query: 932 LSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLP 991
+ FS+N P ++ K L+S S PS P L + P SP+ P
Sbjct: 952 SGPSPFSMNANLPPPPAL------KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQP 1004
Query: 992 ASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGP 1031
S P S P+ L P PF GP
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 1044
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 53.1 bits (126), Expect = 1e-06
Identities = 73/275 (26%), Positives = 94/275 (34%), Gaps = 58/275 (21%)
Query: 627 SEARKTPVTQT-PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF 685
S+A P T P ++ Q P HP PP P P P P PP+ GS
Sbjct: 782 SQAPNQPQAPTAPVPHTHIQQAPALHPQR-PPSPHPPPHPSPH----PPLQPLTGS---- 832
Query: 686 PAGVSVPGTFLQPTAHS---PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQ 742
AG + QP H P + +QAG Q P P P PQ SQ Q
Sbjct: 833 -AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL------QHPGPPQPFGLPPQASQ--GQA 883
Query: 743 PLTSLPAQPTAQSTSQLQV-QALTQQQQSP-------------------TKAVPALG--- 779
PL + PA ++ QL Q+ Q QQ P T +P L
Sbjct: 884 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 943
Query: 780 --KSPPHHSGFQQYQQAD-----------ASKQLWNPPQVQGPLGKIMPVKQPYYLQTQD 826
K PPH SG + +S +PP P ++MP QP
Sbjct: 944 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 1003
Query: 827 PIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNP 861
P L + PP P + P P+ +P
Sbjct: 1004 PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHP 1038
Score = 52.8 bits (125), Expect = 2e-06
Identities = 114/520 (21%), Positives = 167/520 (32%), Gaps = 120/520 (23%)
Query: 518 DGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGI 577
+ S LKS ++++ + ++ T + KT+E++R P E + S
Sbjct: 639 EASSPLKSNKRQREKVASDTEEADR---TSSKKTKTQEISRPNS----PSEGEGESSDSR 691
Query: 578 TVTKNDGKKDNNKRKTETKKCTLEKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQT 637
+V ++G D + + + ++ + Q L+ P + T VT
Sbjct: 692 SVN-DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA 750
Query: 638 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQ 697
P+ A P P LP+ PG P +PP GS P P
Sbjct: 751 PSSA----------PPGTPQLPT-PGPTPSATAVPP-----QGS----PTASQAPNQPQA 790
Query: 698 PTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTS 757
PTA P +Q H QRP P P P S P QPLT QP+A S +
Sbjct: 791 PTAPVPH-THIQQAPALH----PQRPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHA 842
Query: 758 QLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQ---YQQADASKQLWNPPQV---QGPLG 811
Q P G+ PP Q Q + PPQ Q PLG
Sbjct: 843 Q----------------PPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 886
Query: 812 KIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYW 871
P+ T + + +LQ QQ P E+ + P P+
Sbjct: 887 TSPAAAYPH---TSLQLPASQSALQS---QQPPREQPLPPAPLA---------------- 924
Query: 872 DSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSF 931
P + P P+P++P ++ H
Sbjct: 925 -------------------------MPHIKPPPTTPIPQLPAPQA--------HKHPPHL 951
Query: 932 LSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLP 991
+ FS+N P ++ K L+S S PS P L + P SP+ P
Sbjct: 952 SGPSPFSMNANLPPPPAL------KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQP 1004
Query: 992 ASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGP 1031
S P S P+ L P PF GP
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 1044
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 52.4 bits (124), Expect = 2e-06
Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 14/188 (7%)
Query: 703 PAGNQVQAGKQSHI-PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQV 761
P Q Q +Q+H +SQQ+ P PQQ P QQ Q QLQ
Sbjct: 447 PFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQ 506
Query: 762 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYY 821
L QQQ L + HS QQ QQ +Q Q ++ P+
Sbjct: 507 HQLQQQQ---------LAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHL 557
Query: 822 LQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE--FYWDSSYSMAD 879
QT ++ P QPP QQQ + P + + H+P+ V++PE F +++AD
Sbjct: 558 SQTSQALQHQVPPQQPP-QQQQQQQPPPSPQQHQLFGHDPA-VEIPEEGFLLGCVFAIAD 615
Query: 880 NRSVMAQQ 887
M+ +
Sbjct: 616 YPEQMSDK 623
Score = 44.7 bits (104), Expect = 5e-04
Identities = 46/154 (29%), Positives = 65/154 (42%), Gaps = 24/154 (15%)
Query: 699 TAHSPAGN---QVQAGKQSH-----IPYSQQRPSGPGPMNQGPQQSQPPSQQ-PLTSLPA 749
T +P N QV +Q H + +SQ + + M Q QQ+Q QQ P+ L
Sbjct: 362 TLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQP 421
Query: 750 QPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGP 809
Q Q+ L QQQQ P + PPH QQ QQ A ++ Q+Q P
Sbjct: 422 Q---------QIMQLQQQQQQQISQQP-YPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFP 471
Query: 810 LGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQ 843
++ P +Q + Q Q +P Q +QQQ
Sbjct: 472 QQQLHPPQQLHRPQQQ-----LQPFQQQHALQQQ 500
Score = 32.7 bits (73), Expect = 2.0
Identities = 50/291 (17%), Positives = 91/291 (31%), Gaps = 27/291 (9%)
Query: 735 QSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPT------KAVPALGKSPPHHSGF 788
QS S+ T PA T ++ + A QQ P+ + + A K+
Sbjct: 320 QSSERSEMIATWSPAVRTLRNITN---NADIQQMNRPSNVAHILQTLSAPTKNLEQQVNH 376
Query: 789 QQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKK 848
Q +A+ L++ +V + +Q Q Q P+ +P + QQQ +
Sbjct: 377 SQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQIS 436
Query: 849 MKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPV 908
+P+P +P + P A QQ ++ P Q +
Sbjct: 437 QQPYPQQPPH--------PFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQL 488
Query: 909 PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSP 968
+ +L ++ +L H L Q++ + + + + +
Sbjct: 489 QPFQQQHALQQQFHQLQQH----------QLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQ 538
Query: 969 SMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTH 1019
M Q+ + P + H P Q P P SP H
Sbjct: 539 RMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQH 589
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 52.0 bits (123), Expect = 3e-06
Identities = 59/217 (27%), Positives = 72/217 (33%), Gaps = 32/217 (14%)
Query: 657 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ-----AG 711
P+ P PPP ++ PPP + G P G P Q +P G+ V G
Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQG---PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468
Query: 712 KQSHIPYSQQRPSGPGPMNQGPQQSQ---PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQ 768
P P P P Q P PP QQ P P S+ QQ
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528
Query: 769 QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPI 828
+ T G PP +QQ Q A A+ PQ+QG P P Q P+
Sbjct: 529 TTTTTTSAGTGSIPP----WQQQQAAAAASP--GAPQMQG-----NPTMVPLPPGVQPPL 577
Query: 829 KLFEPSLQPPVMQQQPLEKKM-------KPFPMEPYN 858
P PP P M P PM+P N
Sbjct: 578 ---PPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSN 611
Score = 33.9 bits (76), Expect = 0.90
Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 6/49 (12%)
Query: 638 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFP 686
P N +P+ PG PPLP PG PPP PPP S G Y P
Sbjct: 558 PQMQGNPTMVPLP-PGVQPPLP--PGAPPPP---PPPPPGSAGMMYAPP 600
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 51.6 bits (122), Expect = 4e-06
Identities = 108/471 (22%), Positives = 151/471 (32%), Gaps = 87/471 (18%)
Query: 637 TPTQASN-SQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPA-GVSVP 692
+P+ AS+ S F P + P A+ P P PG P P+ Y+ P A S T PA P
Sbjct: 1547 SPSAASDASGFSPGYSP-AWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSP 1605
Query: 693 GTFL-QPTAHSPAGNQVQAGKQSHIPYS-QQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQ 750
G + Q ++SP S+ P S P+ P P S TS
Sbjct: 1606 GGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1665
Query: 751 PTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPL 810
PT+ S S T SPT SP + Y S +P P
Sbjct: 1666 PTSPSYSP------TSPSYSPT--------SPSYSPTSPSYSPTSPSYSPTSPS--YSPT 1709
Query: 811 GKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFY 870
P Y T PS P P P N+ P+
Sbjct: 1710 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSP---TSPNYTPT-------- 1758
Query: 871 WDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSS 930
SYS SP + P P PS + S
Sbjct: 1759 -SPSYS------------------PTSPSYSPTSPNYTPTSPNYSP--TSPSYSPTSPSY 1797
Query: 931 FLSLTGFSLNQERY-PNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPS 989
+ +S + RY P + + +S S + SPS +P TP SPS
Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTP------SSPSYSPSSPSYSPTSPKY------TPTSPS 1845
Query: 990 LPASSDHSTPASQSPHSSNPSSLPSSP-------------PTHNHNSVPFSNFGPIGTPD 1036
SS TP S ++P P+SP P ++ S +S P+ TP
Sbjct: 1846 YSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTP- 1904
Query: 1037 NRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPS 1087
T+ ++ P Y + + + + ST S T G+ P+
Sbjct: 1905 -----TSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPT 1950
Score = 38.9 bits (89), Expect = 0.028
Identities = 38/140 (27%), Positives = 56/140 (40%), Gaps = 18/140 (12%)
Query: 959 TSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP-- 1016
TS S + SPS +P S +P SP+ +S + TP S S ++PS P+SP
Sbjct: 1723 TSPSYSPTSPSYSPTSPSY------SPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNY 1776
Query: 1017 ----PTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWH 1072
P ++ S +S P +P T+ + P Y ++ S S
Sbjct: 1777 TPTSPNYSPTSPSYSPTSPSYSP------TSPSYSPSSPRYTPQSPTYTPSSPSYSPSSP 1830
Query: 1073 QASTPSGTWTGHGPSMEDSS 1092
S S +T PS SS
Sbjct: 1831 SYSPTSPKYTPTSPSYSPSS 1850
Score = 37.7 bits (86), Expect = 0.063
Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 18/140 (12%)
Query: 959 TSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP-- 1016
TS S + SPS +P S +P SPS +S +P S S ++PS P+SP
Sbjct: 1681 TSPSYSPTSPSYSPTSPSY------SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1734
Query: 1017 ----PTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWH 1072
P+++ S +S P TP T+ + P+ +Y + + +
Sbjct: 1735 SPTSPSYSPTSPNYSPTSPNYTP------TSPSYSPTSPSYSPTSPNYTPTSPNYSPTSP 1788
Query: 1073 QASTPSGTWTGHGPSMEDSS 1092
S S +++ PS SS
Sbjct: 1789 SYSPTSPSYSPTSPSYSPSS 1808
Score = 34.3 bits (77), Expect = 0.69
Identities = 37/140 (26%), Positives = 60/140 (42%), Gaps = 19/140 (13%)
Query: 960 SSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP--- 1016
S S + SP+ P+ Y TP SPS +S +P S S ++P+ P+SP
Sbjct: 1590 SPSYSPTSPAYEPRSPGGY-----TPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYS 1644
Query: 1017 ---PTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQ 1073
P+++ S +S P +P T+ + P+ Y S TS S S
Sbjct: 1645 PTSPSYSPTSPSYSPTSPSYSP------TSPSYSPTSPSYSPTSPSY-SPTSPSYSPTSP 1697
Query: 1074 ASTP-SGTWTGHGPSMEDSS 1092
+ +P S +++ PS +S
Sbjct: 1698 SYSPTSPSYSPTSPSYSPTS 1717
Score = 33.9 bits (76), Expect = 0.90
Identities = 36/133 (27%), Positives = 58/133 (43%), Gaps = 20/133 (15%)
Query: 967 SPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP------PTHN 1020
SPS +P S +P SPS +S + +P S S ++PS P+SP P+++
Sbjct: 1612 SPSYSPTSPSY------SPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1665
Query: 1021 HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTP-SG 1079
S +S P +P T+ + P+ Y S TS S S + +P S
Sbjct: 1666 PTSPSYSPTSPSYSP------TSPSYSPTSPSYSPTSPSY-SPTSPSYSPTSPSYSPTSP 1718
Query: 1080 TWTGHGPSMEDSS 1092
+++ PS +S
Sbjct: 1719 SYSPTSPSYSPTS 1731
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 50.8 bits (120), Expect = 7e-06
Identities = 52/190 (27%), Positives = 64/190 (33%), Gaps = 22/190 (11%)
Query: 657 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ-----AG 711
P+ P PPP ++ PPP + G P G P Q +P G+ V G
Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQG---PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468
Query: 712 KQSHIPYSQQRPSGPGPMNQGPQQSQ---PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQ 768
P P P P Q P PP QQ P P S+ QQ
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528
Query: 769 QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPI 828
+ T G PP +QQ Q A A+ PQ+QG P P Q P+
Sbjct: 529 TTTTTTSAGTGSIPP----WQQQQAAAAASP--GAPQMQG-----NPTMVPLPPGVQPPL 577
Query: 829 KLFEPSLQPP 838
P PP
Sbjct: 578 PPGAPPPPPP 587
Score = 31.6 bits (70), Expect = 4.5
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 6/43 (13%)
Query: 638 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMG 680
P N +P+ PG PPLP PG PPP PPP S G
Sbjct: 558 PQMQGNPTMVPLP-PGVQPPLP--PGAPPPP---PPPPPGSAG 594
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 50.8 bits (120), Expect = 7e-06
Identities = 89/384 (23%), Positives = 134/384 (34%), Gaps = 46/384 (11%)
Query: 672 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 731
PPP M + P T LQ A Q Q +Q + QQ+ + Q
Sbjct: 129 PPPGTSGMAPHSMAVVSTATPQTQLQ--LQQVALQQQQQQQQ----FQQQQQAALQQQQQ 182
Query: 732 GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQY 791
QQ Q +QQ Q Q QLQ Q QQQQ K HH QQ
Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQ--QQQQQHLIKL---------HHQNQQQI 231
Query: 792 QQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 851
QQ +QL Q+Q L + +Q Q Q ++ P QPP+ Q QP + P
Sbjct: 232 QQ--QQQQLQRIAQLQ--LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287
Query: 852 FPMEPYNHNPSEVKVPEFYWDSSYSMADNR----SVMAQQANIDRRGKRSPGVFRPEQDP 907
++ +H P+ +A N+ +Q + + + PG Q P
Sbjct: 288 QQLQQMHHTQHHQPPPQ---PQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP 344
Query: 908 ---------VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSM-----FNEV 953
V + P + + ++ + + + ++ + G + E M F
Sbjct: 345 LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPT 404
Query: 954 YGKNLTSSSKAEL--SPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSS 1011
+ SS L P ++SL L +P + P SP PSS
Sbjct: 405 TAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSP-GQQVQTPQSMPPPPQPSPQPGQPSS 463
Query: 1012 LPSSPPTHNHNSVPFSNFGPIGTP 1035
P+S + P S+F P +P
Sbjct: 464 QPNSNVSSGPAPSP-SSFLPSPSP 486
Score = 36.6 bits (83), Expect = 0.14
Identities = 47/166 (28%), Positives = 63/166 (37%), Gaps = 6/166 (3%)
Query: 687 AGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGP-GPMNQGPQQS-QPP---SQ 741
A VS P LQ PA G P G G M Q S QPP S
Sbjct: 76 ASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSG 135
Query: 742 QPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLW 801
S+ TA +QLQ+Q + QQQ + ++ QQ QQ ++Q
Sbjct: 136 MAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSA 195
Query: 802 NPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEK 847
Q Q + + ++Q Q Q IKL + Q QQQ L++
Sbjct: 196 MQQQFQAVVQQQQQLQQQQQ-QQQHLIKLHHQNQQQIQQQQQQLQR 240
Score = 31.2 bits (69), Expect = 5.9
Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 15/143 (10%)
Query: 698 PTAHSPAGNQVQAG-KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQST 756
P++ P G Q A QS +P S P P QQ Q P P P+ Q +
Sbjct: 411 PSSSIPLGRQPMAQVSQSSLPML----SSPSP----GQQVQTPQSMPPPPQPSPQPGQPS 462
Query: 757 SQLQVQALTQQQQSPTKAVPALGKSP---PHHSGFQQYQQADASKQL---WNPPQVQGPL 810
SQ + SP+ +P+ P P + Q + L NP V P
Sbjct: 463 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 522
Query: 811 GKIMPVKQPYYLQTQDPIKLFEP 833
G +Q Y + + K EP
Sbjct: 523 GSSQAEEQQYLDKLKQLSKYIEP 545
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 50.4 bits (119), Expect = 9e-06
Identities = 77/288 (26%), Positives = 99/288 (34%), Gaps = 48/288 (16%)
Query: 602 KLQETGKQNVAVQVKSQTELRKT-PVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS 660
KL E K + A K+Q + R T P+ + + +A +Q +PG LP
Sbjct: 332 KLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQ----PNPGI---LPI 384
Query: 661 RPGFPPP--TYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPY 718
+P P V PPP A + A V P P+ P Q QA + P
Sbjct: 385 QPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLP---QTQAKQPQAPPT 441
Query: 719 SQQRPSG-----PGPMNQGPQQSQP----PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQ 769
QQ PS P PQ Q QQ PAQ T Q QA TQQ Q
Sbjct: 442 PQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQ 501
Query: 770 S--PTKAVPALGKSPPHHSGFQQ-------YQQADASKQLWNPPQV-------------- 806
+ P PA+ + P G Q YQQ +Q Q+
Sbjct: 502 AVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQA 561
Query: 807 ---QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 851
Q P QP P EP++Q PV QQ ++ P
Sbjct: 562 ALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPP 609
Score = 41.6 bits (96), Expect = 0.004
Identities = 49/194 (25%), Positives = 65/194 (33%), Gaps = 15/194 (7%)
Query: 630 RKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGV 689
++TP TQ + +Q P H F + PPP P + T
Sbjct: 443 QQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQA 502
Query: 690 SVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPA 749
P T A P +Q + +Q + QQ Q QQ Q QQ T+L
Sbjct: 503 VHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQ---------QQQQQQQQQQQQLATALHQ 553
Query: 750 QPTAQSTSQLQ---VQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQV 806
Q + LQ A QQ Q A P +P Q + Q PP V
Sbjct: 554 QQLMTQQAALQQKPTMAAGQQPQPQPAAAPQ--PAPAQEPAIQAPVRQQPKVQTTPPPAV 611
Query: 807 QG-PLGKIMPVKQP 819
QG +G + P P
Sbjct: 612 QGQKVGSLTPPSSP 625
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 49.7 bits (117), Expect = 2e-05
Identities = 75/327 (22%), Positives = 121/327 (37%), Gaps = 43/327 (13%)
Query: 657 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI 716
P+P +PG P + PP ++ PA +Q AG Q +AG
Sbjct: 2099 PIPGQPGMPQGQPGLQPPTMPGQQGVHSNPA--------MQNMNPMQAGVQ-RAGLPQQQ 2149
Query: 717 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 776
P Q +P G Q Q + + P +Q L+ Q + QQQQ A P
Sbjct: 2150 PQQQLQPPMGGMSPQAQQMNMNHNTMP---------SQFRDILRRQQMMQQQQQQG-AGP 2199
Query: 777 ALGKSPPHHSGFQQYQ------QADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKL 830
+G +H+ FQQ Q Q Q QG +G+I + Q + ++
Sbjct: 2200 GIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQA 2259
Query: 831 FEPSLQPPVMQQQPLEKKMKPFPMEPYNHN-PSEVKVPEFYWDSSYSMADNRSVMAQQAN 889
++ L QQ + ++P PM P H P++ + P + N+ V + Q
Sbjct: 2260 YQQRL-----LQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQ-VRSPQPV 2313
Query: 890 IDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN--- 946
R + P P P PRM + S + S ++ + Q + +
Sbjct: 2314 PSPRPQSQP----PHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQ 2369
Query: 947 NSMFNEVYGK----NLTSSSKAELSPS 969
NSM +++ NL +S +L S
Sbjct: 2370 NSMLSQLASNPGMANLHGASATDLGLS 2396
Score = 47.0 bits (110), Expect = 1e-04
Identities = 81/331 (24%), Positives = 117/331 (35%), Gaps = 77/331 (23%)
Query: 623 KTPVSEARKTPVT---QTPTQASNSQFIPIH---------HPGAFPPLPSRPGFPPPTYV 670
+ PVS+A+ + + +P SQ IH H + P+PSR P T
Sbjct: 788 QAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHT-- 845
Query: 671 IPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMN 730
PP + T PA V P PA + G QS + R + P
Sbjct: 846 -PPSIGAQQPPATTIPAPVPTP----------PA---MPPGPQSQALHPPPRQTPTPPTT 891
Query: 731 QGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQ 790
Q PQQ QP SLPA A S Q Q Q +QQ + + P PP +
Sbjct: 892 QLPQQVQP-------SLPA---APSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLS 941
Query: 791 YQQADASKQLWNPPQVQGP--LGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKK 848
Q+ NPP + + KQP Q+ +E K
Sbjct: 942 QPAVSIEGQVSNPPSTSSTEVNSQAIAEKQP--------------------SQEVKMEAK 981
Query: 849 MKPFPMEPYNHNP---SEVKVPEFYWDSSYS-------------MADNRSVMAQQANIDR 892
M+ EP + P SE KV + +S+ + D S A Q++
Sbjct: 982 MEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSS-PA 1040
Query: 893 RGKRSPGVFRPEQDPVPRMPFEKSLLEKPSE 923
G+ +F+PE+ MP ++L + E
Sbjct: 1041 PGQSKKKIFKPEELRQALMPTLEALYRQDPE 1071
Score = 42.0 bits (97), Expect = 0.003
Identities = 44/154 (28%), Positives = 58/154 (37%), Gaps = 22/154 (14%)
Query: 709 QAGKQSHIPYSQQRPSGPGPMN-QGPQQSQPPSQQPLTSLP--------AQPTAQSTSQL 759
Q G S P + P+G P Q PQ + P P S+P A P +Q +
Sbjct: 1844 QQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAG 1903
Query: 760 QVQALTQQQQSPTKAVPALGKSPPH--HSGFQQYQQADASKQLWNPPQVQGPLGKIMPVK 817
QV T P A P L PP Q + A+ +Q+ + Q P+ MP
Sbjct: 1904 QVTPPTP----PQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPM 1959
Query: 818 QPYYLQ-------TQDPIKLFEPSLQPPVMQQQP 844
P T+ P EP + P MQQQP
Sbjct: 1960 TPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQP 1993
Score = 37.7 bits (86), Expect = 0.063
Identities = 40/151 (26%), Positives = 55/151 (36%), Gaps = 23/151 (15%)
Query: 692 PGTFLQPTAHSPAG-------NQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQ----PPS 740
P T PT P +Q Q + +P R GP++QG Q P
Sbjct: 1852 PATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPP 1911
Query: 741 QQPLTSLPAQPTAQSTSQLQVQ--ALTQQQQSPTKAV--PALGKSPPHHSGFQQYQQADA 796
Q LP P A +Q+Q A TQ+Q + + P + PP A
Sbjct: 1912 QTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPP--------MTPMA 1963
Query: 797 SKQLWNPPQVQGPLGKIMPVKQPYYLQTQDP 827
+ PP +GP G + P P +Q Q P
Sbjct: 1964 PMGMNPPPMTRGPSGHLEPGMGPTGMQQQPP 1994
Score = 34.7 bits (78), Expect = 0.53
Identities = 141/672 (20%), Positives = 222/672 (33%), Gaps = 133/672 (19%)
Query: 435 DFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELIL 494
D S Q G RR+ QR I + QC N L
Sbjct: 1714 DESNNQQAAATQSPGDSRRLSIQRCIQ-------SLVHACQCRNANCSL----------- 1755
Query: 495 EDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTR 554
PS K ++Q T + G P K +++ + +C + PV F NIK +
Sbjct: 1756 --PSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPV-PFCLNIKQK 1812
Query: 555 EVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTLEKLQETGKQNVAVQ 614
+ ++ R + T G++ T T TG+Q Q
Sbjct: 1813 LRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTT-----PTGQQPTTPQ 1867
Query: 615 VKSQTELRKTPVSEARKTPVTQTPTQASNSQFI-PIHHPGAF----PPLPSRPGFPPPTY 669
P S+ + TP P +Q P+ A PP P + PP
Sbjct: 1868 TPQ-------PTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPG 1920
Query: 670 VIPPPVAFSMGSGYT-----------------------------FPAGVSVPGTFLQPTA 700
PPP A M P G++ P P+
Sbjct: 1921 --PPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSG 1978
Query: 701 H-----SPAGNQVQAG-KQSHIPYSQQRPSG-PGP-MNQGPQQSQPPSQQPLTSL----- 747
H P G Q Q Q +P QQ SG P P M Q QP + P L
Sbjct: 1979 HLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGI 2038
Query: 748 -PAQPTAQSTSQLQVQALTQQQQSPT------KAVPALGKSPPHHSGFQQYQQADASKQL 800
P +P + SQ +Q L + +SP+ + + L +P + F + + A +
Sbjct: 2039 SPLKPG--TVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANS- 2095
Query: 801 WNPPQVQGPLGK----------IMPVKQPYY----LQTQDPIKLFEPSLQPPVMQQQPLE 846
NP + G G MP +Q + +Q +P+ + +Q + QQ +
Sbjct: 2096 -NPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPM---QAGVQRAGLPQQQPQ 2151
Query: 847 KKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKR-SPGVFRPEQ 905
++++P PM + ++ + S + R M QQ G PG+ Q
Sbjct: 2152 QQLQP-PMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQ 2210
Query: 906 DPVPR----MPFEKSLLEKPSELMSHSS---------SFLSLTGFSLN--QERYPNNSMF 950
P+ P ++ ++ + M + + + G SL Q+R M
Sbjct: 2211 FQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMG 2270
Query: 951 NEVYGKNLTSSSKAELSPSMAP--QETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSS- 1007
+ V ++ + + +P Q + + SP P S P SQ PHSS
Sbjct: 2271 SPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQ-PVPSPR--PQSQPPHSSP 2327
Query: 1008 NPSSLPSSPPTH 1019
+P P P H
Sbjct: 2328 SPRMQPQPSPHH 2339
Score = 33.1 bits (74), Expect = 1.5
Identities = 44/168 (26%), Positives = 58/168 (34%), Gaps = 18/168 (10%)
Query: 713 QSHIPYSQQRPSGPGPMNQGPQQSQPPSQ---QPLTSLPAQ-------PTAQSTSQLQV- 761
Q H +Q P PM GP+ QP +Q P T P+Q P A S+ Q V
Sbjct: 734 QHHGQLAQPGALNP-PMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVS 792
Query: 762 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMP----VK 817
QA P + S H Q Q + +P + P P +
Sbjct: 793 QAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQ 852
Query: 818 QPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVK 865
QP T P + P PP Q Q L + P P P +V+
Sbjct: 853 QP--PATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQ 898
Score = 31.6 bits (70), Expect = 4.5
Identities = 35/117 (29%), Positives = 43/117 (36%), Gaps = 12/117 (10%)
Query: 704 AGNQVQAGKQSHIPY--SQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQV 761
AGN + Q P Q GP P+ G + P P T P Q S LQ+
Sbjct: 215 AGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQI 274
Query: 762 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQ 818
Q T+ S + A+ K G Q A PQVQ P G + PV Q
Sbjct: 275 Q--TKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPA-------PQVQQP-GLVTPVAQ 321
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 49.7 bits (117), Expect = 2e-05
Identities = 43/119 (36%), Positives = 49/119 (41%), Gaps = 19/119 (15%)
Query: 633 PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVP 692
P QTP + P+ PG PP P PG PPP V+PPP+A G P V P
Sbjct: 231 PAGQTPPRP------PLGPPG--PPGP--PGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP 280
Query: 693 GTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQP 751
G QP P G + G +P P GP P PQQ PP P P P
Sbjct: 281 G---QPFGQPPLG-PLPPGPPPPVP-GYGPPPGPPP----PQQGPPPPPGPFPPRPPGP 330
Score = 33.1 bits (74), Expect = 1.5
Identities = 26/98 (26%), Positives = 34/98 (34%), Gaps = 11/98 (11%)
Query: 652 PGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAG 711
PG FPP P P PP T PP + P G P + P P N
Sbjct: 320 PGPFPPRPPGPLGPPLTLAPPPHLPGP-------PPGAPPPAPHVNPAFFPPPTNSGMPT 372
Query: 712 KQSHIPYSQQRPSGPGPMNQG----PQQSQPPSQQPLT 745
S P P P ++G P + ++ PL+
Sbjct: 373 SDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLS 410
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 49.7 bits (117), Expect = 2e-05
Identities = 77/343 (22%), Positives = 126/343 (36%), Gaps = 67/343 (19%)
Query: 710 AGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQ 769
+ +Q QQ+ Q QQ Q PS QP SLP+QP +S LQ + L QQ Q
Sbjct: 637 SAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696
Query: 770 SPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPY----YLQTQ 825
+ P G+Q QQ Q Q GP P P Y+ +Q
Sbjct: 697 N----------QPIAGMGYQVSQQ-QRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745
Query: 826 DPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMA 885
+ + + +Q+Q +E+K + + M + +A
Sbjct: 746 QSLLNQQLMGKKQTLQRQIMEQKQQLLLQQ--------------------QMLADAEKIA 785
Query: 886 QQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYP 945
Q I+R R P ++ ++ V M +P+ S SS +SL
Sbjct: 786 PQDQINRHLSRPPPDYKDQRRNVGNM--------QPTAQYSGGSSTISLNS--------- 828
Query: 946 NNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDH----STPAS 1001
N ++ N V + + + + LS S + SL + + +LP + + ++ +
Sbjct: 829 NQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMN 888
Query: 1002 QSPHSSNPSSLPSS--------PPT---HNHNSVPFSNFGPIG 1033
Q NP L ++ PPT N+N+V G +G
Sbjct: 889 QLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVG 931
Score = 32.3 bits (72), Expect = 2.6
Identities = 42/190 (22%), Positives = 61/190 (32%), Gaps = 26/190 (13%)
Query: 681 SGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPM---NQGPQQSQ 737
+ Y + AG S G L + ++ + P + R P+ N Q
Sbjct: 511 ANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQ 570
Query: 738 PPSQQPLTSLPA------QPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQY 791
PS P + P+ Q Q Q Q Q QQQQ QQ
Sbjct: 571 MPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQ-----------------QQQ 613
Query: 792 QQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 851
QQ +Q Q Q + +Q Q Q + + Q QQQP + +
Sbjct: 614 QQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQS 673
Query: 852 FPMEPYNHNP 861
P +P +P
Sbjct: 674 LPSQPLLRSP 683
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 49.7 bits (117), Expect = 2e-05
Identities = 128/544 (23%), Positives = 183/544 (33%), Gaps = 91/544 (16%)
Query: 647 IPIHHP-GAFPPLPSRPGFP--PPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSP 703
+P P G P P P FP PPTY PP G+ PA + G +P A P
Sbjct: 2171 VPSQDPFGLAPAYPLEPRFPTAPPTY---PPYPSPTGA----PAQPPMLGASSRPGAGQP 2223
Query: 704 AG-NQVQAGKQSHIPYSQQ---RPSGPGPMN----QGPQQSQPPSQQPLTSLPAQPTAQS 755
+ G H P + +P P N + P + +PL S P P +S
Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPP--PFGES 2281
Query: 756 TSQLQVQALTQQQQSPTKAVPALG----KSPPHHSGFQQYQQADASKQLWNP------PQ 805
L+V+ SP+ P LG S H G + + D K P PQ
Sbjct: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341
Query: 806 VQG--------PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM---QQQPLEK----KMK 850
G P + + P + P +P QPP+ Q P E +
Sbjct: 2342 SPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPR 2401
Query: 851 PFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQ---ANIDRRGKRSPGVFRPEQDP 907
P +P++ P+ + SS S R + A+ + + R + RP P
Sbjct: 2402 SLPSDPFSRVPASPQSQS----SSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP 2457
Query: 908 VPRMPFEKSLLEKPSELMSHSSSFL--SLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAE 965
R PF L KP +F SL SL +P L + E
Sbjct: 2458 QSRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFP----------AALPAGPAGE 2505
Query: 966 LSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTP-ASQSPHSSNPSSLPSSPPTHNHNSV 1024
L + + + GT P+ + P A P P P PP H NS
Sbjct: 2506 LHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINS- 2564
Query: 1025 PFSNFGP---IGTPDNRDRRTAD-----RWKTDKPAMGGFGIDY-LSATSSSESSWHQAS 1075
+FGP +G P + + A P+ G G Y LS A
Sbjct: 2565 ---HFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621
Query: 1076 TPSGTWTGHGPSM-----------EDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQ 1124
S + HG S ED + SL + PG S L Q +++++
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681
Query: 1125 KQQR 1128
++QR
Sbjct: 2682 QRQR 2685
Score = 44.7 bits (104), Expect = 5e-04
Identities = 77/327 (23%), Positives = 118/327 (36%), Gaps = 57/327 (17%)
Query: 708 VQAGKQSHIPYSQQRPSGP----GPMNQGPQQS--QPPSQQPLTSLPAQPTAQSTSQLQV 761
VQ Q P +++ P P P++ P++S PP + S P + S +
Sbjct: 424 VQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEAL 483
Query: 762 QALTQQQQSPTKAVPALG--KSPPHHSGFQQYQQADASKQLWNPPQ--VQGPLG---KIM 814
++SP P PP S F +++ S +PP ++ PL +
Sbjct: 484 HLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS 543
Query: 815 PVKQPYYLQTQDPIKLFEPSLQPPV---MQQQPLEKKMKPFPME-PYNHNPSEVKVPEFY 870
P+ P+ P P+ PP + P E M P P E P + P ++ +
Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603
Query: 871 WDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSS 930
+S S S ++ R SP PE P+ P E+S + P E+ S
Sbjct: 604 EESPLSPPPEESPLSPPPEASRL---SPP---PEDSPMSPPP-EESPMSPPPEVSRLSPL 656
Query: 931 FLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSL 990
+ + LSP P+E+ L E +P SP
Sbjct: 657 PVV------------------------------SRLSPP--PEESPLSPPPEESPTSPP- 683
Query: 991 PASSDHSTPASQSPHSSNPSSLPSSPP 1017
P +S S P SP S P P+SPP
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPP 710
Score = 43.1 bits (100), Expect = 0.001
Identities = 101/431 (23%), Positives = 142/431 (32%), Gaps = 81/431 (18%)
Query: 623 KTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPP-PTYVIPPPVAFSMG- 680
+TP+S + P + S P P + PP SR PP + + PPP M
Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592
Query: 681 ---SGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQ 737
+ FP P P SP +A + S P + P P P + S
Sbjct: 593 PPEASRLFPPFEESP--LSPPPEESPLSPPPEASRLS--PPPEDSPMSPPP--EESPMSP 646
Query: 738 PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK-SPPHHSGFQQYQQADA 796
PP L+ LP + S + ++SPT P + SPP D+
Sbjct: 647 PPEVSRLSPLPV-VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705
Query: 797 ------SKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMK 850
L + P + PL +P+ + L + P + P + +P E +
Sbjct: 706 PASPPPEDSLMSLPLEESPL---LPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS 762
Query: 851 PFPMEPY----NHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQD 906
P EP+ P VPE S + + S ++ ++ SP P
Sbjct: 763 PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHL------SPQTEEPHLS 816
Query: 907 PVPRMPF---------------EKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFN 951
PVP P E L +P E SH S L S E+ P
Sbjct: 817 PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE--SHLSPELEKPPLSPRPEKPPE----- 869
Query: 952 EVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSL------PASSDHSTPASQSPH 1005
E AP+E L+ P PSL PA S+ P P
Sbjct: 870 -------------EPGQCPAPEELPLFP----PPGEPSLSPLLGEPALSEPGEP----PL 908
Query: 1006 SSNPSSLPSSP 1016
S P LP SP
Sbjct: 909 SPLPEELPLSP 919
Score = 42.4 bits (98), Expect = 0.003
Identities = 61/229 (26%), Positives = 86/229 (37%), Gaps = 23/229 (10%)
Query: 832 EPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANID 891
EP L+ P+ ++ PL + P+ P PE S S + + ++
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486
Query: 892 RRGKRSPGVFRPEQDPV-------PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERY 944
R + SP PE+ P+ P P E+S L P E S S L T S E
Sbjct: 487 RPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE--SPPSPALE-TPLSPPPEAS 543
Query: 945 PNNSMFNEVY----GKNLTSSSKAELSP-SMAPQETSLYSLFEGTPWSPSLPAS------ 993
P + F E + L +S E S S P+E+ + E +P SP AS
Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603
Query: 994 --SDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDR 1040
S S P +SP S P + SPP + P P+ P R
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Score = 39.3 bits (90), Expect = 0.021
Identities = 91/416 (21%), Positives = 144/416 (34%), Gaps = 38/416 (9%)
Query: 621 LRKTPVSEA-RKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSM 679
L ++P+S ++P++ P +S F P+ PP S P T + PPP A +
Sbjct: 489 LEESPLSPPPEESPLSPPP---ESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPL 545
Query: 680 GSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGP----GPMNQGPQQ 735
+ + +S P L PT+ P +++ P ++ P P PM+ P+
Sbjct: 546 SPPFE-ESPLSPPPEEL-PTSPPPEASRLS-------PPPEESPMSPPPEESPMSPPPEA 596
Query: 736 SQ--PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALG-KSPPHHSGFQQYQ 792
S+ PP ++ S P + + S + + SP P SPP +
Sbjct: 597 SRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPE--VSRLS 654
Query: 793 QADASKQLWNPPQVQGPLG---KIMPVKQPYYLQTQDPIKLFEPSLQPP--VMQQQPLEK 847
+L +PP + PL + P P P P+ PP P E
Sbjct: 655 PLPVVSRL-SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPED 713
Query: 848 KMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKR---SPGVFRPE 904
+ P+E P +PE S + S ++ ++ R + SP P
Sbjct: 714 SLMSLPLEESPLLP----LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPH 769
Query: 905 QDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKA 964
P P P ++ E+P LS L+ + V + S
Sbjct: 770 LSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPE 829
Query: 965 ELSPSMAPQETSLYSLFEGTPWSPSL---PASSDHSTPASQSPHSSNPSSLPSSPP 1017
E S +E L E + SP L P S P + P LP PP
Sbjct: 830 ESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP 885
Score = 35.4 bits (80), Expect = 0.31
Identities = 73/301 (24%), Positives = 102/301 (33%), Gaps = 47/301 (15%)
Query: 569 VRRDYSKGITVTKNDGKKDNNK-RKTETKKCTLEKLQETGKQNVAVQVKSQTELRKTPVS 627
V R K + + KK + + + +K L Q++ Q QV+ Q + ++
Sbjct: 3534 VHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMA 3593
Query: 628 EARKTPVTQTPTQASNSQ-------FIPIHHPGAFPPLPSR----PGFPPPTYVIPPPVA 676
E R Q Q Q P P LP + G PP PP
Sbjct: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQ---GPPGG 3650
Query: 677 FSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQS 736
+ G T P G+++PG P ++ Q Q QQ G G + GP
Sbjct: 3651 QAGGLRLT-PGGMALPGQPGGPFLNTALAQQQQ----------QQHSGGAGSL-AGPSGG 3698
Query: 737 QPPSQQPLTSLPA-------------QPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPP 783
P L SL Q Q +LQ Q QQQQ A+ +
Sbjct: 3699 FFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQ 3758
Query: 784 HHSGFQQYQQADASKQ-LWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQ 842
G Q Q Q L P QG L + + + P Q P + P+ Q V+QQ
Sbjct: 3759 QGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPP-----QGPQGMLGPA-QVAVLQQ 3812
Query: 843 Q 843
Q
Sbjct: 3813 Q 3813
Score = 32.7 bits (73), Expect = 2.0
Identities = 51/179 (28%), Positives = 62/179 (34%), Gaps = 20/179 (11%)
Query: 707 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 766
Q Q +Q + QQ+ Q Q Q QQ L Q Q QLQ Q Q
Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQ 3962
Query: 767 ----QQQSPTKAVPALGKSPPHHSGFQQYQQADA--------SKQLWNPPQVQGPLGKIM 814
QQQ + + L +S S QQ QQ A Q ++ P GP +
Sbjct: 3963 QQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLT 4022
Query: 815 PVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDS 873
+Q T DP E + P Q PL P E P EVK P DS
Sbjct: 4023 GKEQ----NTVDPAVSSEATEGPSTHQGGPLAIGTTP---ESMATEPGEVK-PSLSGDS 4073
Score = 32.0 bits (71), Expect = 3.4
Identities = 51/241 (21%), Positives = 88/241 (36%), Gaps = 18/241 (7%)
Query: 618 QTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAF 677
+ L P+ E+ P+ + P S+ + P L RP P ++ P
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEP---HLSPQAEEP 768
Query: 678 SMGSGYTFPAGVSVPGT-FLQPTAH----SPAGNQVQAGKQSHIPYSQQRPSGPGPMNQG 732
+ P +VP L P A SP ++ Q+ P+ P P ++
Sbjct: 769 HLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPC-LSPQ 827
Query: 733 PQQSQ--PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQ 790
P++S P S++P S P + + +L+ L+ + + P + P +P F
Sbjct: 828 PEESHLSPQSEEPCLS-PRPEESHLSPELEKPPLSPRPEKPPEE-PGQCPAPEELPLFPP 885
Query: 791 YQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMK 850
+ S L P + + P+ + L EPSL P +M PL +
Sbjct: 886 PGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG-----EPSLSPQLMPPDPLPPPLS 940
Query: 851 P 851
P
Sbjct: 941 P 941
Score = 32.0 bits (71), Expect = 3.4
Identities = 35/128 (27%), Positives = 47/128 (36%), Gaps = 17/128 (13%)
Query: 692 PGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPP----SQQPLTSL 747
PGT P G Q Q G + G GP QGP + P S P+
Sbjct: 4246 PGTQTSPL-QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG- 4303
Query: 748 PAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQ 807
P PT +S Q Q SP+ +P + PP H G + Q P ++
Sbjct: 4304 PVHPTPPPSSP-QEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQ----------GPTLE 4352
Query: 808 GPLGKIMP 815
P G++ P
Sbjct: 4353 PPPGRVSP 4360
Score = 31.6 bits (70), Expect = 4.5
Identities = 40/164 (24%), Positives = 54/164 (32%), Gaps = 4/164 (2%)
Query: 651 HPGAFPPL-PSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ 709
HPGA P P R + V+ P G G V+ Q H G+
Sbjct: 3814 HPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQ-QQQQQHQQQGSMAG 3872
Query: 710 AG--KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQ 767
+QS + +S Q PM Q Q Q L Q Q Q Q+Q Q
Sbjct: 3873 LSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQ 3932
Query: 768 QQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLG 811
QQ + + + Q QQ +Q + Q Q +G
Sbjct: 3933 QQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976
Score = 31.2 bits (69), Expect = 5.9
Identities = 101/454 (22%), Positives = 157/454 (34%), Gaps = 94/454 (20%)
Query: 614 QVKSQTELRKTPVSEA-RKTPVTQTP-TQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVI 671
Q+++ R+ S+A R+TP Q P TQ S Q G P GFP P
Sbjct: 4221 QLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQ-------GLLGCQPQLGGFPGPQ--- 4270
Query: 672 PPPVAFSMGSG--------YTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRP 723
P+ +G+G P G G L P +P + P +RP
Sbjct: 4271 TGPLQ-ELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSS---------PQEPKRP 4320
Query: 724 SG-PGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSP 782
S P P +Q P ++Q P P T P PT + A Q + T LG
Sbjct: 4321 SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAA--QLADTLFSKGLGPWD 4378
Query: 783 PHHSGFQQYQQADASKQLWNPPQVQG---PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPV 839
P + + + +S + QV G P + +KQ EP +P
Sbjct: 4379 PPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQ-------------EPREEPCA 4425
Query: 840 MQQQPLEKKMKPFPM---EPYNH--------NPSEVKVPEFYWDSSYSMADNRSVMAQQA 888
+ Q ++++ P+ NH + + + + ++ R +A
Sbjct: 4426 LGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRA 4485
Query: 889 NIDRR--------GKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLN 940
I+ ++ G ++D R P L KP + S +S S
Sbjct: 4486 EINGHIDSKLAGLEQKLQGTPSNKEDAAARKP----LTPKPKRVQKASDRLVS----SRK 4537
Query: 941 QERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLF---------------EGTP 985
+ R + +E K L + L P P T+ +SLF G
Sbjct: 4538 KLRKEDGVRASEALLKQL--KQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAF 4595
Query: 986 WSPSLPASSDHSTPASQSPHSSNPSSLPSS-PPT 1018
S +LP D+ + + SNP + PSS PPT
Sbjct: 4596 GSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPT 4629
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 49.3 bits (116), Expect = 2e-05
Identities = 94/406 (23%), Positives = 155/406 (38%), Gaps = 56/406 (13%)
Query: 607 GKQNVAVQVKSQTE-LRKTPVSEARKTPVTQTPT---QASNSQFIPIHHPGA----FPPL 658
G+ + ++V E L +P + R +P Q S FIP+H P PP+
Sbjct: 1125 GEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSPQESALLFIPVHSPSTEGPQLPPV 1184
Query: 659 PSRPGFPPPTY-VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIP 717
P+ P + P P+ P+ + HSP +Q ++ P
Sbjct: 1185 PAATQEKSPEERLFPEPLLPKEKPKADAPSDLKA--------VHSPIRSQPVTLPEARTP 1236
Query: 718 YSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPA 777
S P P P + PPS P+ S P QP+ ++T + QSP + PA
Sbjct: 1237 VS---PGSPQPQPPVAASTPPPSPLPICSQP-QPSTEAT-------VPSPTQSPIRFQPA 1285
Query: 778 LGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQP 837
K+ + Q+D +L +P V L + V++ +++++ + +
Sbjct: 1286 PAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEE-FWMKSAEIRR-------- 1336
Query: 838 PVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRS 897
+ P+++ P P P P+ V + S D + + +I +R
Sbjct: 1337 -SLGLTPVDRSKGPEPSFP---TPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKR---- 1388
Query: 898 PGVFRPEQDPV----PRMPFEKSLLEKPSELMS-HSSSFLSLTGFSLNQERYPNNSMFNE 952
G+ +PE +P+ PR P ++ L E SSS L L G S N + + S FN
Sbjct: 1389 LGLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQS-FNT 1447
Query: 953 VYGKNLTSSSKAELSPSMAPQETSL-YSLFEGTPWS----PSLPAS 993
LT S P + +L L E P + P LPA+
Sbjct: 1448 SDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPAT 1493
>gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]
Length = 463
Score = 48.9 bits (115), Expect = 3e-05
Identities = 67/291 (23%), Positives = 94/291 (32%), Gaps = 30/291 (10%)
Query: 629 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 688
A T P Q P+ PG PP+P PG PP + P V M G
Sbjct: 122 AASTSFQPQPVQPQQGYIPPMAQPG-LPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
Query: 689 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPG--PMNQGPQQSQPPSQQPLTS 746
+ PG H Q G+ +P P GPG P+ G PP P
Sbjct: 181 MP-PGLH-----HQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPG----MPPGMPPPVP 230
Query: 747 LPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQV 806
P P + + + +PT VPA + P F QA A+ V
Sbjct: 231 RPGIPPMTQAQAVSAPGILNRPPAPTATVPA-PQPPVTKPLFPSAGQAQAA--------V 281
Query: 807 QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKV 866
QGP+G T +P K P+ P P+ +
Sbjct: 282 QGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTT 341
Query: 867 PE-----FYWDSSYSMADNRSVMAQ-QANIDRRGKRSPGVFRPEQDPVPRM 911
+ D S+ + R+ + + Q N+ R G+ G P P+ M
Sbjct: 342 TSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPIGGM 390
Score = 32.3 bits (72), Expect = 2.6
Identities = 47/200 (23%), Positives = 68/200 (34%), Gaps = 28/200 (14%)
Query: 644 SQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGV-SVPGTFLQPTAHS 702
+ F P++ A P +P FP T + + + A + S P T +A S
Sbjct: 287 TDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATS 346
Query: 703 PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 762
+ I ++R P P+ P Q P+ + P P + Q
Sbjct: 347 KLIHP-----DEDISLEERRAQLPKYQRNLPR----PGQAPIGNPPVGPIG---GMMPPQ 394
Query: 763 ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 822
QQQ +P G+ HH G Y PP QGP P+ PY
Sbjct: 395 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAM------PPYGQGP-----PMVPPYQG 443
Query: 823 QTQDPIKLFEPSLQPPVMQQ 842
P ++PPVM Q
Sbjct: 444 GPPRP----PMGMRPPVMSQ 459
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 48.5 bits (114), Expect = 4e-05
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 7/165 (4%)
Query: 648 PIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG---VSVPGT-FLQPTAHSP 703
P+ PG PP P P ++ PP + G FP G V+ PGT L PT
Sbjct: 78 PMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIW 137
Query: 704 AGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQA 763
N+ GK + Y+ + G + Q P+ + AQ AQ+ +Q Q QA
Sbjct: 138 VENKTPDGKVYY--YNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQA 195
Query: 764 LTQQQQSPTKAVPALGKSPPHHSGFQQYQ-QADASKQLWNPPQVQ 807
Q Q A ++ Q Q QA A Q Q Q
Sbjct: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
Score = 35.8 bits (81), Expect = 0.24
Identities = 59/296 (19%), Positives = 97/296 (32%), Gaps = 38/296 (12%)
Query: 604 QETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPG 663
Q + QV++Q + + + TP T +P A ++ S P
Sbjct: 232 QAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTS-----------TSSSTPS 280
Query: 664 FPPPTYVIPPPVAFSMGS----GYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSH---- 715
T VA ++ + T + VSV + + +P VQ Q H
Sbjct: 281 STTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTL 340
Query: 716 ---IPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPT 772
+P+S +P+ P P PP + PL +P Q
Sbjct: 341 PPAVPHSVPQPTTAIPAF--PPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAI 398
Query: 773 KAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFE 832
A PA S + +Y+ AD +N ++ K +K+ L+ K+ E
Sbjct: 399 AASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEE----KIKE 454
Query: 833 PSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQA 888
P +P +P PME +P E + E + AQ+A
Sbjct: 455 PIKEP----------SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKA 500
Score = 33.1 bits (74), Expect = 1.5
Identities = 41/152 (26%), Positives = 55/152 (36%), Gaps = 26/152 (17%)
Query: 652 PGAFPPL--PSRPGFPP----------PTYVIPPPVAFSMGSGYTFPAGVSV-------P 692
P PP+ P P PP P + A + S +T P GV V P
Sbjct: 116 PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTP 175
Query: 693 GTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQ-QPLTSLPAQP 751
Q + A Q QA Q+ Q + Q Q+Q +Q Q AQ
Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 235
Query: 752 TAQSTSQLQVQALTQQQ------QSPTKAVPA 777
AQ+ +Q+Q Q Q Q +PT + PA
Sbjct: 236 QAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA 267
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 48.5 bits (114), Expect = 4e-05
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 7/165 (4%)
Query: 648 PIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG---VSVPGT-FLQPTAHSP 703
P+ PG PP P P ++ PP + G FP G V+ PGT L PT
Sbjct: 78 PMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIW 137
Query: 704 AGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQA 763
N+ GK + Y+ + G + Q P+ + AQ AQ+ +Q Q QA
Sbjct: 138 VENKTPDGKVYY--YNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQA 195
Query: 764 LTQQQQSPTKAVPALGKSPPHHSGFQQYQ-QADASKQLWNPPQVQ 807
Q Q A ++ Q Q QA A Q Q Q
Sbjct: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
Score = 36.2 bits (82), Expect = 0.18
Identities = 65/317 (20%), Positives = 108/317 (34%), Gaps = 59/317 (18%)
Query: 604 QETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPG 663
Q + QV++Q + + + TP T +P A ++ S P
Sbjct: 232 QAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTS-----------TSSSTPS 280
Query: 664 FPPPTYVIPPPVAFSMGS----GYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSH---- 715
T VA ++ + T + VSV + + +P VQ Q H
Sbjct: 281 STTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTL 340
Query: 716 ---IPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP------AQPTAQSTSQLQVQALTQ 766
+P+S +P+ P P PP + PL +P A S ++ A T+
Sbjct: 341 PPAVPHSVPQPTTAIPAF--PPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTK 398
Query: 767 QQQSPTKAVP---------ALGKSPPHHSG------FQQYQQADASKQLWNPPQVQGPLG 811
P A P A+ SP +G + +Y+ AD +N ++
Sbjct: 399 TGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWE 458
Query: 812 KIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYW 871
K +K+ L+ K+ EP +P +P PME +P E + E
Sbjct: 459 KPQELKEKEKLEE----KIKEPIKEP----------SEEPLPMETEEEDPKEEPIKEIKE 504
Query: 872 DSSYSMADNRSVMAQQA 888
+ AQ+A
Sbjct: 505 EPKEEEMTEEEKAAQKA 521
Score = 33.1 bits (74), Expect = 1.5
Identities = 41/152 (26%), Positives = 55/152 (36%), Gaps = 26/152 (17%)
Query: 652 PGAFPPL--PSRPGFPP----------PTYVIPPPVAFSMGSGYTFPAGVSV-------P 692
P PP+ P P PP P + A + S +T P GV V P
Sbjct: 116 PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTP 175
Query: 693 GTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQ-QPLTSLPAQP 751
Q + A Q QA Q+ Q + Q Q+Q +Q Q AQ
Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 235
Query: 752 TAQSTSQLQVQALTQQQ------QSPTKAVPA 777
AQ+ +Q+Q Q Q Q +PT + PA
Sbjct: 236 QAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA 267
>gi|50345881 cytoplasmic polyadenylation element binding protein 3
[Homo sapiens]
Length = 698
Score = 48.1 bits (113), Expect = 5e-05
Identities = 62/290 (21%), Positives = 91/290 (31%), Gaps = 78/290 (26%)
Query: 605 ETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGF 664
+T Q Q + Q ++ VSEA TP++ + + +P P A PP P+ P
Sbjct: 11 KTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDK 70
Query: 665 --------------------PPPTYVIPPPVAFSMGSGYTFPAGVS-------------V 691
PPP P + S G T+ G + V
Sbjct: 71 MQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPV 130
Query: 692 PGTFL--------QPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQP 743
GT L P Q+ + H Q+P P P Q Q +QPP QP
Sbjct: 131 NGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQH----HQQPPPPAPAPQPAQPAQPPQAQP 186
Query: 744 --LTSLPAQPTAQSTSQLQV------QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQAD 795
PA P+ +Q Q + + S + AV A + S +
Sbjct: 187 PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQ 246
Query: 796 ASKQLWNPPQ-------------------------VQGPLGKIMPVKQPY 820
+ W+ P V PL I P+K+P+
Sbjct: 247 SVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPF 296
Score = 32.3 bits (72), Expect = 2.6
Identities = 58/278 (20%), Positives = 97/278 (34%), Gaps = 37/278 (13%)
Query: 825 QDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPS---EVKVPEFYWDSSYSMADNR 881
QD + + + QP QQQ ++ +P P + PS + P+ +S+
Sbjct: 2 QDDLLMDKSKTQPQPQQQQ--RQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPA 59
Query: 882 SVMAQQANIDRRGKRSPGV------FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLT 935
+ D+ SP + P+Q P P+ P PS + S+ +
Sbjct: 60 AAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAV 119
Query: 936 GFSLNQERYP-NNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASS 994
S Q P N +M + + ++ SP + +T + + P +P+ +
Sbjct: 120 EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQ--QPPPPAPAPQPAQ 177
Query: 995 DHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMG 1054
P +Q P + PS P ++ PI T KP+
Sbjct: 178 PAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPI--------------MTSKPSSS 223
Query: 1055 GF--GIDYLSATSSSESSW--HQA-----STPSGTWTG 1083
+A SS+ SSW HQ+ S PS W G
Sbjct: 224 SAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGG 261
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 48.1 bits (113), Expect = 5e-05
Identities = 85/382 (22%), Positives = 120/382 (31%), Gaps = 54/382 (14%)
Query: 664 FPPPTYVIPPPVAF---SMGSGY---TFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI- 716
+PPP PPPVA S G GY T PA S G H Q+Q Q +
Sbjct: 14 YPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQ 73
Query: 717 ----PYSQQRPSGPGPM-----NQGPQQSQPPSQQPLTSLPAQP--TAQSTSQLQVQALT 765
P+ P P P G Q PP P P P + Q Q + Q L
Sbjct: 74 CVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPP----PPGPALSYQKQQQYKHQMLH 129
Query: 766 QQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQ 825
Q+ P VP +SPP +PP P G MP Q Y Q
Sbjct: 130 HQRDGPPGLVPMELESPPE-----------------SPPV---PPGSYMPPSQSYMPPPQ 169
Query: 826 DPIKLFEPS--------LQPPVMQQQPLEKKMKPFPMEPYNHNPSE--VKVPEFYWDSSY 875
P + P+ QP Q P + + P P + + S+ + + Y SS
Sbjct: 170 PPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQ 229
Query: 876 SMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLT 935
+ S ++ + P + V + P E K +E + T
Sbjct: 230 ASPSRPSQGHSKSQL--LAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPST 287
Query: 936 GFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSD 995
Q++Y + + + P +A P + +P S
Sbjct: 288 MTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPS 347
Query: 996 HSTPASQSPHSSNPSSLPSSPP 1017
P P+ P LP P
Sbjct: 348 SEEPPLPPPNEEVPPPLPPEEP 369
Score = 47.0 bits (110), Expect = 1e-04
Identities = 90/457 (19%), Positives = 164/457 (35%), Gaps = 70/457 (15%)
Query: 612 AVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVI 671
A+ + Q + + + R P P + + P PG++ P PS+ PPP
Sbjct: 114 ALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMP-PSQSYMPPPQ--- 169
Query: 672 PPPVAFSMGSGYTF-------PAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ---- 720
PPP + S + P+ ++L PT P+ + + QS++ +SQ
Sbjct: 170 PPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT---PSYSSSSSSSQSYLSHSQSYLP 226
Query: 721 QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQA---LTQQQQSPTKAVPA 777
+ P +QG +SQ + P ++ P T L+ A T+QQQ+ + P+
Sbjct: 227 SSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPS 286
Query: 778 LGKSPPHHSGFQQYQQADASKQ----LWNPPQVQGPL---GKIMPVKQPYYLQTQDPIKL 830
P Y+Q S Q + P +GP+ PVK+ + +
Sbjct: 287 --TMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPE 344
Query: 831 FEPSLQPPVMQQQPLEKKMKPF-PMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQAN 889
S +PP+ P E+ P P EP + +P E D+ + QQ
Sbjct: 345 SPSSEEPPL--PPPNEEVPPPLPPEEPQSEDPEE--------DARLKQLQAAAAHWQQHQ 394
Query: 890 IDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQER------ 943
R G + G+ + + + +++ P + + S + L + + Q++
Sbjct: 395 QHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVD-MQLRHYEMQQQQFQHLYQ 453
Query: 944 ---------------YPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP 988
YP+ E + T + + S ++ + + +
Sbjct: 454 EWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKN----- 508
Query: 989 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVP 1025
+ S P P+S P LP+ PP S+P
Sbjct: 509 --QYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLP 543
Score = 36.2 bits (82), Expect = 0.18
Identities = 49/227 (21%), Positives = 80/227 (35%), Gaps = 19/227 (8%)
Query: 559 DQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTLEKLQETGKQNVAVQVKSQ 618
+Q S+P K+ ++Y K + K + + + K Q G ++
Sbjct: 464 EQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPY 523
Query: 619 TELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFS 678
+++ P+ P P P A P PG PPP V+PP + S
Sbjct: 524 SQM---------PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPP--VMPPSLPTS 572
Query: 679 MGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQ- 737
+ P G+ + P P + AG +P + P P+ P S
Sbjct: 573 VP-----PPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSA 627
Query: 738 -PPSQQPLTSLP-AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSP 782
PP P +P P + + + + +Q Q P K PAL +P
Sbjct: 628 TPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTP 674
Score = 31.6 bits (70), Expect = 4.5
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 8/74 (10%)
Query: 658 LPSRPGFPPPTY--VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSH 715
+PS P PPP IPPP MG P P +Q T G + K
Sbjct: 1602 IPSAPVLPPPPVHSSIPPPGPVPMGMP---PMSKPPP---VQQTVDYGHGRDISTNKVEQ 1655
Query: 716 IPYSQQRPSGPGPM 729
IPY ++ P P+
Sbjct: 1656 IPYGERITLRPDPL 1669
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,762,927
Number of Sequences: 37866
Number of extensions: 2597024
Number of successful extensions: 15460
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 767
Number of HSP's that attempted gapping in prelim test: 10982
Number of HSP's gapped (non-prelim): 3852
length of query: 1137
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1024
effective length of database: 13,968,660
effective search space: 14303907840
effective search space used: 14303907840
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.