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Search of human proteins with 41349443
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41349443 potassium channel, subfamily T, member 2 [Homo
sapiens]
(1135 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens] 2296 0.0
gi|240255505 potassium channel, subfamily T, member 1 [Homo sapi... 1782 0.0
gi|157074214 potassium channel, subfamily U, member 1 [Homo sapi... 142 2e-33
gi|62388890 large conductance calcium-activated potassium channe... 125 3e-28
gi|238624132 large conductance calcium-activated potassium chann... 124 4e-28
gi|238624130 large conductance calcium-activated potassium chann... 124 4e-28
gi|26638650 large conductance calcium-activated potassium channe... 124 4e-28
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 43 0.002
gi|163792201 Shaw-related voltage-gated potassium channel protei... 43 0.002
gi|88758576 Shaw-related voltage-gated potassium channel protein... 43 0.002
gi|24497462 Shaw-related voltage-gated potassium channel protein... 43 0.002
gi|24497464 Shaw-related voltage-gated potassium channel protein... 43 0.002
gi|21217561 Shaw-related voltage-gated potassium channel protein... 42 0.003
gi|21217563 Shaw-related voltage-gated potassium channel protein... 42 0.003
gi|24497458 Shaw-related voltage-gated potassium channel protein... 42 0.003
gi|24497460 Shaw-related voltage-gated potassium channel protein... 42 0.003
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 41 0.006
gi|22024390 potassium voltage-gated channel, subfamily H, member... 41 0.007
gi|27886648 potassium voltage-gated channel, subfamily H, member... 41 0.007
gi|27886646 potassium voltage-gated channel, subfamily H, member... 41 0.007
gi|4504831 potassium voltage-gated channel, subfamily H, member ... 39 0.021
gi|27437001 potassium voltage-gated channel, subfamily H, member... 39 0.021
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H... 39 0.021
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 39 0.021
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 38 0.048
gi|160420295 hypothetical protein LOC85459 [Homo sapiens] 37 0.081
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i... 37 0.11
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i... 37 0.11
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 37 0.11
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 37 0.11
>gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens]
Length = 1135
Score = 2296 bits (5951), Expect = 0.0
Identities = 1135/1135 (100%), Positives = 1135/1135 (100%)
Query: 1 MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSL 60
MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSL
Sbjct: 1 MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSL 60
Query: 61 RIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVSVALISLFETI 120
RIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVSVALISLFETI
Sbjct: 61 RIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVSVALISLFETI 120
Query: 121 LLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENM 180
LLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENM
Sbjct: 121 LLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENM 180
Query: 181 INDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTF 240
INDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTF
Sbjct: 181 INDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTF 240
Query: 241 STVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEK 300
STVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEK
Sbjct: 241 STVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEK 300
Query: 301 HVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYL 360
HVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYL
Sbjct: 301 HVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYL 360
Query: 361 QGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQIL 420
QGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQIL
Sbjct: 361 QGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQIL 420
Query: 421 KPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKM 480
KPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKM
Sbjct: 421 KPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKM 480
Query: 481 YGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRREDNKNILLNPGP 540
YGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRREDNKNILLNPGP
Sbjct: 481 YGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRREDNKNILLNPGP 540
Query: 541 RYIMNSTDICFYINITKEENSAFKNQDQQRKSNVSRSFYHGPSRLPVHSIIASMGTVAID 600
RYIMNSTDICFYINITKEENSAFKNQDQQRKSNVSRSFYHGPSRLPVHSIIASMGTVAID
Sbjct: 541 RYIMNSTDICFYINITKEENSAFKNQDQQRKSNVSRSFYHGPSRLPVHSIIASMGTVAID 600
Query: 601 LQDTSCRSASGPTLSLPTEGSKEIRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEE 660
LQDTSCRSASGPTLSLPTEGSKEIRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEE
Sbjct: 601 LQDTSCRSASGPTLSLPTEGSKEIRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEE 660
Query: 661 MSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKL 720
MSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKL
Sbjct: 661 MSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKL 720
Query: 721 IIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGS 780
IIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGS
Sbjct: 721 IIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGS 780
Query: 781 IDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELT 840
IDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELT
Sbjct: 781 IDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELT 840
Query: 841 HPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQS 900
HPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQS
Sbjct: 841 HPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQS 900
Query: 901 FVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVPIGIYR 960
FVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVPIGIYR
Sbjct: 901 FVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVPIGIYR 960
Query: 961 TESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARR 1020
TESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARR
Sbjct: 961 TESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARR 1020
Query: 1021 LSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTL 1080
LSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTL
Sbjct: 1021 LSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTL 1080
Query: 1081 SYILINPSPDTRIELNDVVYLIRPDPLAYLPNSEPSRRNSICNVTGQDSREETQL 1135
SYILINPSPDTRIELNDVVYLIRPDPLAYLPNSEPSRRNSICNVTGQDSREETQL
Sbjct: 1081 SYILINPSPDTRIELNDVVYLIRPDPLAYLPNSEPSRRNSICNVTGQDSREETQL 1135
>gi|240255505 potassium channel, subfamily T, member 1 [Homo sapiens]
Length = 1235
Score = 1782 bits (4616), Expect = 0.0
Identities = 896/1185 (75%), Positives = 1006/1185 (84%), Gaps = 53/1185 (4%)
Query: 1 MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSL 60
M DL+SEV PLPPRYRFRDLLLGD +QNDDRVQVEFY+NENTFKERLKLFFIKNQRSSL
Sbjct: 54 MSDLDSEVLPLPPRYRFRDLLLGDPSFQNDDRVQVEFYVNENTFKERLKLFFIKNQRSSL 113
Query: 61 RIRLFNFSLKLLSCLLYIIRVLLENPSQGN-------------------EWSHIFWVNRS 101
RIRLFNFSLKLL+CLLYI+RVLL++P+ G W+ I WV R
Sbjct: 114 RIRLFNFSLKLLTCLLYIVRVLLDDPALGIGCWGCPKQNYSFNDSSSEINWAPILWVERK 173
Query: 102 LPLWGLQVSVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRN 161
+ LW +QV VA+IS ET+LL YLSYKGNIWEQI R+ F+LE+IN +PFII+IFWP LRN
Sbjct: 174 MTLWAIQVIVAIISFLETMLLIYLSYKGNIWEQIFRVSFVLEMINTLPFIITIFWPPLRN 233
Query: 162 LFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLE 221
LF+PVFLNCWLAKHALENMIND HRAI RTQSAMFNQVLIL TLLCL+FT CGIQHLE
Sbjct: 234 LFIPVFLNCWLAKHALENMINDFHRAILRTQSAMFNQVLILFCTLLCLVFTGTCGIQHLE 293
Query: 222 RIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLW 281
R G+ L+L S YFCIVTFSTVG+GDVTP+ W S+L VV MICVALVVLP+QFE+L YLW
Sbjct: 294 RAGENLSLLTSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLW 353
Query: 282 MERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMD 341
MERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMD
Sbjct: 354 MERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMD 413
Query: 342 VQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTIL 401
VQVRRVLQIP+WSQRVIYLQGSALKDQDL+RAKMD+ EACFILSSR EVDRT++DHQTIL
Sbjct: 414 VQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTIL 473
Query: 402 RAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLL 461
RAWAVKDFAPNCPLYVQILKPENKFH+KFADHVVCEEE KYAMLALNCICPATSTLITLL
Sbjct: 474 RAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPATSTLITLL 533
Query: 462 VHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGV 521
VHTSRGQEGQ+SPEQWQ+MYGRCSGNEVYHI + +S FF EYEGKSFTYA+FHAHKK+GV
Sbjct: 534 VHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAFHAHKKYGV 593
Query: 522 CLIGVRREDNKNILLNPGPRYIMNSTDICFYINITKEENSA--FKNQDQQRKSNVS-RSF 578
CLIG++REDNK+ILLNPGPR+I+ ++D CFYINITKEENSA FK +++++K S +
Sbjct: 594 CLIGLKREDNKSILLNPGPRHILAASDTCFYINITKEENSAFIFKQEEKRKKRAFSGQGL 653
Query: 579 YHGPSRLPVHSIIASMGTVAIDLQDTSCR------SASGPTLSLPTEGSKEIRRPSIAPV 632
+ GP+RLPVHSIIASMGTVA+DLQ T R G L+LPTE RRPSIAPV
Sbjct: 654 HEGPARLPVHSIIASMGTVAMDLQGTEHRPTQSGGGGGGSKLALPTENGSGSRRPSIAPV 713
Query: 633 LEVADTSSIQTCDLLSDQSEDETTP-DEEMSSNLEYAKGYPPYSPYIGSSPTFCHLLHEK 691
LE+AD+S++ CDLLSDQSEDE TP D+E S +EY KGYPP SPYIGSSPT CHLL K
Sbjct: 714 LELADSSALLPCDLLSDQSEDEVTPSDDEGLSVVEYVKGYPPNSPYIGSSPTLCHLLPVK 773
Query: 692 VPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNP 751
PFCCLRLDK C+HN YEDAKAYGFKNKLIIV+AETAGNGLYNFIVPLRAYYR +KELNP
Sbjct: 774 APFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNP 833
Query: 752 IVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEE 811
IVLLLDN PD HFL+AIC FPMVYYM GS+DNLD LL+CG+ +A N+VVVDKESTMSAEE
Sbjct: 834 IVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSLLQCGIIYADNLVVVDKESTMSAEE 893
Query: 812 DYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERG 871
DYMADAKTIVNVQT+FRLF SLSI TELTHP+NMRFMQFRAKD YSLALSKLEK+ERE G
Sbjct: 894 DYMADAKTIVNVQTMFRLFPSLSITTELTHPSNMRFMQFRAKDSYSLALSKLEKRERENG 953
Query: 872 SNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKIT 931
SNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMI+ITRLLLGLDTTPGSG+LC+MKIT
Sbjct: 954 SNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKIT 1013
Query: 932 ADDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSE-------SQISISVEEWEDTK 984
DLWIRTY RL+QKLCSS+ ++PIGIYRTES +TSE SQIS++VE+ EDT+
Sbjct: 1014 EGDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHVFSTSEPHDLRAQSQISVNVEDCEDTR 1073
Query: 985 DSKEQGHHR------SNHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGK--TAEKI 1036
+ K R S R++ D ++HPLLRRKS+QWARRLSRK PK +G+ AE I
Sbjct: 1074 EVKGPWGSRAGTGGSSQGRHTGGGDPAEHPLLRRKSLQWARRLSRKAPKQAGRAAAAEWI 1133
Query: 1037 TQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTLSYILINPSPDTRIELN 1096
+QQRL+LYRRSERQEL+ELVKNRMKHLGL T GYDEMNDHQ+TLSY+LINP PDTR+E +
Sbjct: 1134 SQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYDEMNDHQNTLSYVLINPPPDTRLEPS 1193
Query: 1097 DVVYLIRPDPLAYLPNSEPSRRNSI------CNVTGQDSREETQL 1135
D+VYLIR DPLA++ +S SR++S CN ++R+ETQL
Sbjct: 1194 DIVYLIRSDPLAHVASSSQSRKSSCSHKLSSCN---PETRDETQL 1235
>gi|157074214 potassium channel, subfamily U, member 1 [Homo
sapiens]
Length = 1149
Score = 142 bits (358), Expect = 2e-33
Identities = 198/852 (23%), Positives = 357/852 (41%), Gaps = 161/852 (18%)
Query: 137 RIPFILEIINAVPFIISIFWPSLRNLFVPVFLNC-WLAKHALENM-------INDLHRAI 188
+I F LE+ + I+ IF ++ F+ +L WL L + I + RAI
Sbjct: 163 KIKFWLEMNS----IVDIF--TIPPTFISYYLKSNWLGLRFLRALRLLELPQILQILRAI 216
Query: 189 QRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIG---------KKLNLFDSLYFCIVT 239
+ + S F++ L+S +L FT I +E G + ++ F+S+Y + T
Sbjct: 217 KTSNSVKFSK---LLSIILSTWFTAAGFIHLVENSGDPWLKGRNSQNISYFESIYLVMAT 273
Query: 240 FSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTE 299
STVGFGDV +T + F++ +L++ ++ L+ ++K +Y + +
Sbjct: 274 TSTVGFGDVVAKTSLGRTFIMFFTLGSLILFANYIPEMVELFANKRKYTSSYEALKGK-- 331
Query: 300 KHVVLCVSSLKIDLLMDFLNEFYAHPRLQ-DYYVVILCPTEMDVQVRRVLQIPMWSQRVI 358
K +V+C ++ +D + FL F + + +V L T +++ + + +
Sbjct: 332 KFIVVC-GNITVDSVTAFLRNFLRDKSGEINTEIVFLGETPPSLELETIFKC--YLAYTT 388
Query: 359 YLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQ 418
++ GSA+K +DL R ++ AEAC I+++ D + D I+R ++K++ + +Q
Sbjct: 389 FISGSAMKWEDLRRVAVESAEACLIIANPLCSDSHAEDISNIMRVLSIKNYDSTTRIIIQ 448
Query: 419 ILKPENKFHI--------KFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEG 470
IL+ NK ++ D+++C E K +A C+ P T +T L Q
Sbjct: 449 ILQSHNKVYLPKIPSWNWDTGDNIICFAELKLGFIAQGCLVPGLCTFLTSLFVE---QNK 505
Query: 471 QQSPEQ-WQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVR-- 527
+ P+Q W+K + N++ L + ++ G SF + K + LI +
Sbjct: 506 KVMPKQTWKKHFLNSMKNKILTQRLSD-----DFAGMSFPEVARLCFLKMHLLLIAIEYK 560
Query: 528 ---REDNKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQQRKSNVSRSFYHGPSR 584
+ ++LNP P+ + + F+I T ++ R++ S H
Sbjct: 561 SLFTDGFCGLILNPPPQVRIRKNTLGFFIAETPKD---------VRRALFYCSVCHDDVF 611
Query: 585 LPVHSIIASMGTVAIDLQDTSCRSASGPTLSLPT--------EGSKEIRRPSIAPVLEVA 636
+P +I + G C+S S +++P+ +G +P A
Sbjct: 612 IP--ELITNCG----------CKSRSRQHITVPSVKRMKKCLKGISSRISGQDSPPRVSA 659
Query: 637 DTSSIQTCDLLSDQSEDETTPDEEMSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCC 696
TSSI + Q + E D+ SS + + PT + K
Sbjct: 660 STSSISNFTTRTLQHDVEQDSDQLDSSGM-----------FHWCKPTSLDKVTLK----- 703
Query: 697 LRLDKSCQHNYYEDAKAYGFKNKLIIVA---AETAGNGLYNFIVPLRAYYRPKKELNPIV 753
R KS Y F+N ++ A +A GL NF++PLRA +KEL IV
Sbjct: 704 -RTGKS----------KYKFRNHIVACVFGDAHSAPMGLRNFVMPLRASNYTRKELKDIV 752
Query: 754 LL--LDN-PPDMHFLDAICW-FPMVYYMVG--------SIDNLDDLLRCGVTF-----AA 796
+ LD + FL W FP +Y + G N++ C V ++
Sbjct: 753 FIGSLDYLQREWRFL----WNFPQIYILPGCALYSGDLHAANIEQCSMCAVLSPPPQPSS 808
Query: 797 NMVVVDKESTM------SAEEDYMADAKTIVNVQTLFRL--------FSSLSIITELTHP 842
N +VD E+ M S + D +D V+ +T + I+TEL +P
Sbjct: 809 NQTLVDTEAIMATLTIGSLQIDSSSDPSPSVSEETPGYTNGHNEKSNCRKVPILTELKNP 868
Query: 843 ANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFV 902
+N+ F++ L LE +E +L+ F+ G VFS S LD+LL +F
Sbjct: 869 SNIHFIE---------QLGGLEGSLQETNLHLS----TAFSTGTVFSGSFLDSLLATAFY 915
Query: 903 KDYMISITRLLL 914
+++ + ++L+
Sbjct: 916 NYHVLELLQMLV 927
>gi|62388890 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform a [Homo sapiens]
Length = 1182
Score = 125 bits (313), Expect = 3e-28
Identities = 129/493 (26%), Positives = 210/493 (42%), Gaps = 65/493 (13%)
Query: 107 LQVSVALISLFETIL-LGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVP 165
LQ+ +A F L +++ +W F LE+ + V F ++ +FV
Sbjct: 215 LQIDMAFNVFFLLYFGLRFIAANDKLW-------FWLEVNSVVDFF------TVPPVFVS 261
Query: 166 VFLN-CWLAKHALENMINDLHRAIQRTQSAMFNQVLI------LISTLLCLIFTCI--CG 216
V+LN WL L + R IQ ++ F +L L++ L I T + G
Sbjct: 262 VYLNRSWLGLRFLRAL-----RLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAG 316
Query: 217 IQHL-ERIG---------KKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVA 266
HL E G + L ++ +Y +VT STVG+GDV +T +LF+V I
Sbjct: 317 FIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG 376
Query: 267 LVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPR 326
L + ++ L R+K GG+YS KH+V+C + ++ + +FL +F H
Sbjct: 377 LAMFASYVPEIIELIGNRKKYGGSYSA--VSGRKHIVVC-GHITLESVSNFLKDFL-HKD 432
Query: 327 LQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSS 386
D V I+ + + +V + QGS L DL R K++ A+AC IL++
Sbjct: 433 RDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILAN 492
Query: 387 RCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHI--------KFADHVVCEE 438
+ D + D I+R ++K++ P + Q+L+ NK H+ K D +C
Sbjct: 493 KYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLA 552
Query: 439 EFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEEST 498
E K +A +C+ ST++ L S + + WQK Y NE+Y L +
Sbjct: 553 ELKLGFIAQSCLAQGLSTMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA- 609
Query: 499 FFAEYEGKSFTYASFHAHKKFGVCLIGV-------RREDNKNILLNPGPRYIMNSTDICF 551
+ G SF K + +I + K IL+NPG + + F
Sbjct: 610 ----FVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQEGTLGF 665
Query: 552 YI-NITKEENSAF 563
+I + KE AF
Sbjct: 666 FIASDAKEVKRAF 678
Score = 37.0 bits (84), Expect = 0.11
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 832 SLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSIS 891
++ IITEL + N++F+ ++ + + PFA G F++S
Sbjct: 944 NIPIITELVNDTNVQFLD----------------QDDDDDPDTELYLTQPFACGTAFAVS 987
Query: 892 MLDTLLYQSFVKDYMISITRLLLGLDTTP 920
+LD+L+ ++ D ++++ R L+ TP
Sbjct: 988 VLDSLMSATYFNDNILTLIRTLVTGGATP 1016
>gi|238624132 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform d [Homo sapiens]
Length = 1219
Score = 124 bits (312), Expect = 4e-28
Identities = 128/489 (26%), Positives = 210/489 (42%), Gaps = 61/489 (12%)
Query: 107 LQVSVALISLFETIL-LGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVP 165
LQ+ +A F L +++ +W F LE+ + V F ++ +FV
Sbjct: 215 LQIDMAFNVFFLLYFGLRFIAANDKLW-------FWLEVNSVVDFF------TVPPVFVS 261
Query: 166 VFLN-CWLAKHALENMINDLHRAIQRTQSAMFNQVLI------LISTLLCLIFTCI--CG 216
V+LN WL L + R IQ ++ F +L L++ L I T + G
Sbjct: 262 VYLNRSWLGLRFLRAL-----RLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAG 316
Query: 217 IQHL-ERIG---------KKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVA 266
HL E G + L ++ +Y +VT STVG+GDV +T +LF+V I
Sbjct: 317 FIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG 376
Query: 267 LVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPR 326
L + ++ L R+K GG+YS KH+V+C + ++ + +FL +F H
Sbjct: 377 LAMFASYVPEIIELIGNRKKYGGSYSA--VSGRKHIVVC-GHITLESVSNFLKDFL-HKD 432
Query: 327 LQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSS 386
D V I+ + + +V + QGS L DL R K++ A+AC IL++
Sbjct: 433 RDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILAN 492
Query: 387 RCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHI--------KFADHVVCEE 438
+ D + D I+R ++K++ P + Q+L+ NK H+ K D +C
Sbjct: 493 KYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLA 552
Query: 439 EFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEEST 498
E K +A +C+ ST++ L S + + WQK Y NE+Y L +
Sbjct: 553 ELKLGFIAQSCLAQGLSTMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA- 609
Query: 499 FFAEYEGKSFTYASFHAHKKFGVCLIGVRRED---NKNILLNPGPRYIMNSTDICFYI-N 554
+ G SF K + +I + + IL+NPG + + F+I +
Sbjct: 610 ----FVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIAS 665
Query: 555 ITKEENSAF 563
KE AF
Sbjct: 666 DAKEVKRAF 674
Score = 37.0 bits (84), Expect = 0.11
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 832 SLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSIS 891
++ IITEL + N++F+ ++ + + PFA G F++S
Sbjct: 981 NIPIITELVNDTNVQFLD----------------QDDDDDPDTELYLTQPFACGTAFAVS 1024
Query: 892 MLDTLLYQSFVKDYMISITRLLLGLDTTP 920
+LD+L+ ++ D ++++ R L+ TP
Sbjct: 1025 VLDSLMSATYFNDNILTLIRTLVTGGATP 1053
>gi|238624130 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform c [Homo sapiens]
Length = 1236
Score = 124 bits (312), Expect = 4e-28
Identities = 128/489 (26%), Positives = 210/489 (42%), Gaps = 61/489 (12%)
Query: 107 LQVSVALISLFETIL-LGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVP 165
LQ+ +A F L +++ +W F LE+ + V F ++ +FV
Sbjct: 215 LQIDMAFNVFFLLYFGLRFIAANDKLW-------FWLEVNSVVDFF------TVPPVFVS 261
Query: 166 VFLN-CWLAKHALENMINDLHRAIQRTQSAMFNQVLI------LISTLLCLIFTCI--CG 216
V+LN WL L + R IQ ++ F +L L++ L I T + G
Sbjct: 262 VYLNRSWLGLRFLRAL-----RLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAG 316
Query: 217 IQHL-ERIG---------KKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVA 266
HL E G + L ++ +Y +VT STVG+GDV +T +LF+V I
Sbjct: 317 FIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG 376
Query: 267 LVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPR 326
L + ++ L R+K GG+YS KH+V+C + ++ + +FL +F H
Sbjct: 377 LAMFASYVPEIIELIGNRKKYGGSYSA--VSGRKHIVVC-GHITLESVSNFLKDFL-HKD 432
Query: 327 LQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSS 386
D V I+ + + +V + QGS L DL R K++ A+AC IL++
Sbjct: 433 RDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILAN 492
Query: 387 RCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHI--------KFADHVVCEE 438
+ D + D I+R ++K++ P + Q+L+ NK H+ K D +C
Sbjct: 493 KYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLA 552
Query: 439 EFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEEST 498
E K +A +C+ ST++ L S + + WQK Y NE+Y L +
Sbjct: 553 ELKLGFIAQSCLAQGLSTMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA- 609
Query: 499 FFAEYEGKSFTYASFHAHKKFGVCLIGVRRED---NKNILLNPGPRYIMNSTDICFYI-N 554
+ G SF K + +I + + IL+NPG + + F+I +
Sbjct: 610 ----FVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIAS 665
Query: 555 ITKEENSAF 563
KE AF
Sbjct: 666 DAKEVKRAF 674
Score = 37.0 bits (84), Expect = 0.11
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 832 SLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSIS 891
++ IITEL + N++F+ ++ + + PFA G F++S
Sbjct: 998 NIPIITELVNDTNVQFLD----------------QDDDDDPDTELYLTQPFACGTAFAVS 1041
Query: 892 MLDTLLYQSFVKDYMISITRLLLGLDTTP 920
+LD+L+ ++ D ++++ R L+ TP
Sbjct: 1042 VLDSLMSATYFNDNILTLIRTLVTGGATP 1070
>gi|26638650 large conductance calcium-activated potassium channel
subfamily M alpha member 1 isoform b [Homo sapiens]
Length = 1178
Score = 124 bits (312), Expect = 4e-28
Identities = 128/489 (26%), Positives = 210/489 (42%), Gaps = 61/489 (12%)
Query: 107 LQVSVALISLFETIL-LGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVP 165
LQ+ +A F L +++ +W F LE+ + V F ++ +FV
Sbjct: 215 LQIDMAFNVFFLLYFGLRFIAANDKLW-------FWLEVNSVVDFF------TVPPVFVS 261
Query: 166 VFLN-CWLAKHALENMINDLHRAIQRTQSAMFNQVLI------LISTLLCLIFTCI--CG 216
V+LN WL L + R IQ ++ F +L L++ L I T + G
Sbjct: 262 VYLNRSWLGLRFLRAL-----RLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAG 316
Query: 217 IQHL-ERIG---------KKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVA 266
HL E G + L ++ +Y +VT STVG+GDV +T +LF+V I
Sbjct: 317 FIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGG 376
Query: 267 LVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPR 326
L + ++ L R+K GG+YS KH+V+C + ++ + +FL +F H
Sbjct: 377 LAMFASYVPEIIELIGNRKKYGGSYSA--VSGRKHIVVC-GHITLESVSNFLKDFL-HKD 432
Query: 327 LQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSS 386
D V I+ + + +V + QGS L DL R K++ A+AC IL++
Sbjct: 433 RDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILAN 492
Query: 387 RCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHI--------KFADHVVCEE 438
+ D + D I+R ++K++ P + Q+L+ NK H+ K D +C
Sbjct: 493 KYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLA 552
Query: 439 EFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEEST 498
E K +A +C+ ST++ L S + + WQK Y NE+Y L +
Sbjct: 553 ELKLGFIAQSCLAQGLSTMLANLF--SMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSA- 609
Query: 499 FFAEYEGKSFTYASFHAHKKFGVCLIGVRRED---NKNILLNPGPRYIMNSTDICFYI-N 554
+ G SF K + +I + + IL+NPG + + F+I +
Sbjct: 610 ----FVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIAS 665
Query: 555 ITKEENSAF 563
KE AF
Sbjct: 666 DAKEVKRAF 674
Score = 37.0 bits (84), Expect = 0.11
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 832 SLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSIS 891
++ IITEL + N++F+ ++ + + PFA G F++S
Sbjct: 940 NIPIITELVNDTNVQFLD----------------QDDDDDPDTELYLTQPFACGTAFAVS 983
Query: 892 MLDTLLYQSFVKDYMISITRLLLGLDTTP 920
+LD+L+ ++ D ++++ R L+ TP
Sbjct: 984 VLDSLMSATYFNDNILTLIRTLVTGGATP 1012
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 42.7 bits (99), Expect = 0.002
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 186 RAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKK------------LNLFDSL 233
R + T A N+ L+LI L + I + ERIG + N+
Sbjct: 332 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGF 391
Query: 234 YFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPI 272
++ +VT +T+G+GD+ P+TWS L V +C VL I
Sbjct: 392 WWAVVTMTTLGYGDMYPQTWSGML--VGALCALAGVLTI 428
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 42.7 bits (99), Expect = 0.002
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 186 RAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKK------------LNLFDSL 233
R + T A N+ L+LI L + I + ERIG + N+
Sbjct: 332 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGF 391
Query: 234 YFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPI 272
++ +VT +T+G+GD+ P+TWS L V +C VL I
Sbjct: 392 WWAVVTMTTLGYGDMYPQTWSGML--VGALCALAGVLTI 428
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 42.7 bits (99), Expect = 0.002
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 186 RAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKK------------LNLFDSL 233
R + T A N+ L+LI L + I + ERIG + N+
Sbjct: 368 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGF 427
Query: 234 YFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPI 272
++ +VT +T+G+GD+ P+TWS L V +C VL I
Sbjct: 428 WWAVVTMTTLGYGDMYPKTWSGML--VGALCALAGVLTI 464
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 42.7 bits (99), Expect = 0.002
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 186 RAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKK------------LNLFDSL 233
R + T A N+ L+LI L + I + ERIG + N+
Sbjct: 368 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGF 427
Query: 234 YFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPI 272
++ +VT +T+G+GD+ P+TWS L V +C VL I
Sbjct: 428 WWAVVTMTTLGYGDMYPKTWSGML--VGALCALAGVLTI 464
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 42.7 bits (99), Expect = 0.002
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 186 RAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKK------------LNLFDSL 233
R + T A N+ L+LI L + I + ERIG + N+
Sbjct: 368 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGF 427
Query: 234 YFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPI 272
++ +VT +T+G+GD+ P+TWS L V +C VL I
Sbjct: 428 WWAVVTMTTLGYGDMYPKTWSGML--VGALCALAGVLTI 464
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 42.4 bits (98), Expect = 0.003
Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 186 RAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKK------------LNLFDSL 233
R + T A N+ L+LI L + I + ER+G + N+
Sbjct: 369 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGF 428
Query: 234 YFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPI 272
++ +VT +T+G+GD+ P+TWS L V +C VL I
Sbjct: 429 WWAVVTMTTLGYGDMYPQTWSGML--VGALCALAGVLTI 465
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 42.4 bits (98), Expect = 0.003
Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 186 RAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKK------------LNLFDSL 233
R + T A N+ L+LI L + I + ER+G + N+
Sbjct: 369 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGF 428
Query: 234 YFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPI 272
++ +VT +T+G+GD+ P+TWS L V +C VL I
Sbjct: 429 WWAVVTMTTLGYGDMYPQTWSGML--VGALCALAGVLTI 465
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 42.4 bits (98), Expect = 0.003
Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 186 RAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKK------------LNLFDSL 233
R + T A N+ L+LI L + I + ER+G + N+
Sbjct: 369 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGF 428
Query: 234 YFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPI 272
++ +VT +T+G+GD+ P+TWS L V +C VL I
Sbjct: 429 WWAVVTMTTLGYGDMYPQTWSGML--VGALCALAGVLTI 465
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 42.0 bits (97), Expect = 0.003
Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 19/128 (14%)
Query: 186 RAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKK------------LNLFDSL 233
R + T A N+ L+LI L + I + ERIG N+
Sbjct: 435 RVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGF 494
Query: 234 YFCIVTFSTVGFGDVTPETWSSKLF--VVAMICVALVVLPI-----QFEQLAYLWMERQK 286
++ +VT +T+G+GD+ P+TWS L + A+ V + +P+ F L M +QK
Sbjct: 495 WWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQK 554
Query: 287 SGGNYSRH 294
++H
Sbjct: 555 LPKKKNKH 562
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 41.2 bits (95), Expect = 0.006
Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Query: 200 LILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDV 248
++LI L ++ +C + G + DSLYFC VTFST+GFGD+
Sbjct: 216 VLLILGLFAVLLSCCASAMYTSVEG--WDYVDSLYFCFVTFSTIGFGDL 262
>gi|22024390 potassium voltage-gated channel, subfamily H, member 5
isoform 1 [Homo sapiens]
Length = 988
Score = 40.8 bits (94), Expect = 0.007
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 17/176 (9%)
Query: 232 SLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNY 291
SLYF + + +T+GFG++ P T K+F VAM+ V ++ F + ++ + + Y
Sbjct: 422 SLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRY 481
Query: 292 SRHRAQTEKHVVLC-VSSLKIDLLMDFLNEFYAHPR-LQDYYVVILCPTEMDVQVRRVLQ 349
+ L V + +MD++ ++ + + V+ +CP +M + L
Sbjct: 482 HEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLN 541
Query: 350 IPMWSQRVIY-------LQGSALKDQ-------DLLRAKMDDAEA-CFILSSRCEV 390
++++ + L+ A++ Q DL+ + +A CF++S EV
Sbjct: 542 RKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEV 597
>gi|27886648 potassium voltage-gated channel, subfamily H, member 5
isoform 2 [Homo sapiens]
Length = 624
Score = 40.8 bits (94), Expect = 0.007
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 17/176 (9%)
Query: 232 SLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNY 291
SLYF + + +T+GFG++ P T K+F VAM+ V ++ F + ++ + + Y
Sbjct: 364 SLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRY 423
Query: 292 SRHRAQTEKHVVLC-VSSLKIDLLMDFLNEFYAHPR-LQDYYVVILCPTEMDVQVRRVLQ 349
+ L V + +MD++ ++ + + V+ +CP +M + L
Sbjct: 424 HEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLN 483
Query: 350 IPMWSQRVIY-------LQGSALKDQ-------DLLRAKMDDAEA-CFILSSRCEV 390
++++ + L+ A++ Q DL+ + +A CF++S EV
Sbjct: 484 RKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEV 539
>gi|27886646 potassium voltage-gated channel, subfamily H, member 5
isoform 3 [Homo sapiens]
Length = 611
Score = 40.8 bits (94), Expect = 0.007
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 17/176 (9%)
Query: 232 SLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNY 291
SLYF + + +T+GFG++ P T K+F VAM+ V ++ F + ++ + + Y
Sbjct: 422 SLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRY 481
Query: 292 SRHRAQTEKHVVLC-VSSLKIDLLMDFLNEFYAHPR-LQDYYVVILCPTEMDVQVRRVLQ 349
+ L V + +MD++ ++ + + V+ +CP +M + L
Sbjct: 482 HEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLN 541
Query: 350 IPMWSQRVIY-------LQGSALKDQ-------DLLRAKMDDAEA-CFILSSRCEV 390
++++ + L+ A++ Q DL+ + +A CF++S EV
Sbjct: 542 RKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEV 597
>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
isoform 2 [Homo sapiens]
Length = 962
Score = 39.3 bits (90), Expect = 0.021
Identities = 25/115 (21%), Positives = 54/115 (46%), Gaps = 2/115 (1%)
Query: 232 SLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNY 291
SLYF + + ++VGFG++ P T K+F VA++ + ++ F + ++ + + Y
Sbjct: 426 SLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRY 485
Query: 292 SRHRAQTEKHVVLC-VSSLKIDLLMDFLNEFYAHPR-LQDYYVVILCPTEMDVQV 344
+ L V + +MD++ ++ R + V+ +CP +M +
Sbjct: 486 HEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADI 540
>gi|27437001 potassium voltage-gated channel, subfamily H, member 1
isoform 1 [Homo sapiens]
Length = 989
Score = 39.3 bits (90), Expect = 0.021
Identities = 25/115 (21%), Positives = 54/115 (46%), Gaps = 2/115 (1%)
Query: 232 SLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNY 291
SLYF + + ++VGFG++ P T K+F VA++ + ++ F + ++ + + Y
Sbjct: 453 SLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRY 512
Query: 292 SRHRAQTEKHVVLC-VSSLKIDLLMDFLNEFYAHPR-LQDYYVVILCPTEMDVQV 344
+ L V + +MD++ ++ R + V+ +CP +M +
Sbjct: 513 HEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADI 567
>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
sapiens]
Length = 872
Score = 39.3 bits (90), Expect = 0.021
Identities = 16/43 (37%), Positives = 29/43 (67%), Gaps = 2/43 (4%)
Query: 231 DSLYFCIVTFSTVGFGDVTPETWSSKLFVV--AMICVALVVLP 271
D+L++ ++T +T+G+GD TP+TW +L ++I V+ LP
Sbjct: 305 DALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALP 347
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 39.3 bits (90), Expect = 0.021
Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 10/48 (20%)
Query: 201 ILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDV 248
ILIS ++T I G + FDSLYFC V FST+GFGD+
Sbjct: 206 ILISCCASAMYTPIEGWSY----------FDSLYFCFVAFSTIGFGDL 243
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 38.1 bits (87), Expect = 0.048
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 7/81 (8%)
Query: 194 AMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTP-ET 252
A+ + VL+ T+ C F LE N +S YFC ++ ST+G GD P E
Sbjct: 180 AIVHAVLLGFVTVSCFFFIPAAVFSVLE---DDWNFLESFYFCFISLSTIGLGDYVPGEG 236
Query: 253 WSSK---LFVVAMICVALVVL 270
++ K L+ + + C L+ L
Sbjct: 237 YNQKFRELYKIGITCYLLLGL 257
>gi|160420295 hypothetical protein LOC85459 [Homo sapiens]
Length = 2601
Score = 37.4 bits (85), Expect = 0.081
Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 17/137 (12%)
Query: 935 LWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRS 994
L++ + L +++CS + P ++ T+ S DTK K Q H S
Sbjct: 974 LYVHKQSELDRRVCSEQAE-PSFPFQVAQHTFTSLPSA---------DTKSGKIQEQHSS 1023
Query: 995 NHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSG--KTAEKITQQRLNLYRRSERQEL 1052
S QSD P+ + S+ + ++ P H E++T+QR L R E Q
Sbjct: 1024 KSEKGLVSCQSDIPISQDGSLSFLQQFL---PLHDSLKLLQEQLTKQRDTLQARHEAQ-- 1078
Query: 1053 AELVKNRMKHLGLSTVG 1069
EL+ +R + LG S G
Sbjct: 1079 VELLLHRQRDLGDSKSG 1095
>gi|26638655 potassium voltage-gated channel KQT-like protein 4
isoform b [Homo sapiens]
Length = 641
Score = 37.0 bits (84), Expect = 0.11
Identities = 15/43 (34%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
Query: 231 DSLYFCIVTFSTVGFGDVTPETWSSKLFVV--AMICVALVVLP 271
DSL++ +T +T+G+GD TP TW ++ A++ ++ LP
Sbjct: 272 DSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALP 314
>gi|26638653 potassium voltage-gated channel KQT-like protein 4
isoform a [Homo sapiens]
Length = 695
Score = 37.0 bits (84), Expect = 0.11
Identities = 15/43 (34%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
Query: 231 DSLYFCIVTFSTVGFGDVTPETWSSKLFVV--AMICVALVVLP 271
DSL++ +T +T+G+GD TP TW ++ A++ ++ LP
Sbjct: 272 DSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALP 314
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 37.0 bits (84), Expect = 0.11
Identities = 27/136 (19%), Positives = 60/136 (44%), Gaps = 19/136 (13%)
Query: 202 LISTLLCLIFTCICGIQHLERIGKKL---NLFDSLYFCIVTFSTVGFGDVT--------- 249
+IST++ ++F C+ + I K + + D++YF ++T +T+GFGD
Sbjct: 208 IISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYL 267
Query: 250 ----PETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLC 305
P W +++ + VL + + L + + ++ G + H A+ +V
Sbjct: 268 DFYKPVVW---FWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAE 324
Query: 306 VSSLKIDLLMDFLNEF 321
+ L ++ ++F
Sbjct: 325 FKETRRRLSVEIYDKF 340
Score = 32.3 bits (72), Expect = 2.6
Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 17/130 (13%)
Query: 156 WPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLI-------------L 202
W ++ +F+ V L + + + H QRT + Q I L
Sbjct: 44 WKTVSTIFLVVVLYLIIGATVFK-ALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDEL 102
Query: 203 ISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAM 262
I ++ I I + + +L S +F +T+GFG+++P T K+F
Sbjct: 103 IQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIF---C 159
Query: 263 ICVALVVLPI 272
I AL+ +P+
Sbjct: 160 IIYALLGIPL 169
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 37.0 bits (84), Expect = 0.11
Identities = 27/136 (19%), Positives = 60/136 (44%), Gaps = 19/136 (13%)
Query: 202 LISTLLCLIFTCICGIQHLERIGKKL---NLFDSLYFCIVTFSTVGFGDVT--------- 249
+IST++ ++F C+ + I K + + D++YF ++T +T+GFGD
Sbjct: 223 IISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYL 282
Query: 250 ----PETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLC 305
P W +++ + VL + + L + + ++ G + H A+ +V
Sbjct: 283 DFYKPVVW---FWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAE 339
Query: 306 VSSLKIDLLMDFLNEF 321
+ L ++ ++F
Sbjct: 340 FKETRRRLSVEIYDKF 355
Score = 32.3 bits (72), Expect = 2.6
Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 17/130 (13%)
Query: 156 WPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLI-------------L 202
W ++ +F+ V L + + + H QRT + Q I L
Sbjct: 59 WKTVSTIFLVVVLYLIIGATVFK-ALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDEL 117
Query: 203 ISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAM 262
I ++ I I + + +L S +F +T+GFG+++P T K+F
Sbjct: 118 IQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIF---C 174
Query: 263 ICVALVVLPI 272
I AL+ +P+
Sbjct: 175 IIYALLGIPL 184
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,787,505
Number of Sequences: 37866
Number of extensions: 1859877
Number of successful extensions: 4868
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 4723
Number of HSP's gapped (non-prelim): 160
length of query: 1135
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1022
effective length of database: 13,968,660
effective search space: 14275970520
effective search space used: 14275970520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.