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Search of human proteins with 41327776
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 792 0.0
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 769 0.0
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 313 2e-85
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 231 1e-60
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 219 5e-57
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 203 3e-52
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 198 6e-51
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 193 3e-49
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 193 3e-49
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 190 2e-48
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 189 4e-48
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 184 1e-46
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 184 1e-46
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 184 1e-46
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 183 2e-46
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 182 5e-46
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 181 1e-45
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 181 1e-45
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 180 2e-45
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 176 4e-44
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 175 6e-44
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 175 6e-44
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi... 173 2e-43
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 172 4e-43
gi|4758112 HLA-B associated transcript 1 [Homo sapiens] 172 5e-43
gi|18375623 HLA-B associated transcript 1 [Homo sapiens] 172 5e-43
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 172 5e-43
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 172 5e-43
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi... 169 4e-42
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 164 2e-40
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 792 bits (2046), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ
Sbjct: 1 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
Query: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG
Sbjct: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
Query: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180
VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL
Sbjct: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180
Query: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240
NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ
Sbjct: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240
Query: 241 YYIFIPSKFKSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIH 300
YYIFIPSKFKSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIH
Sbjct: 241 YYIFIPSKFKSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIH 300
Query: 301 RVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRF 360
RVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRF
Sbjct: 301 RVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRF 360
Query: 361 ARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 406
ARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
Sbjct: 361 ARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 406
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 769 bits (1986), Expect = 0.0
Identities = 406/455 (89%), Positives = 406/455 (89%), Gaps = 49/455 (10%)
Query: 1 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ
Sbjct: 1 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
Query: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG
Sbjct: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
Query: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180
VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL
Sbjct: 121 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL 180
Query: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240
NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ
Sbjct: 181 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ 240
Query: 241 YYIFIPSKFK-------------------------------------------------S 251
YYIFIPSKFK S
Sbjct: 241 YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS 300
Query: 252 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 311
KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS
Sbjct: 301 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 360
Query: 312 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK 371
GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK
Sbjct: 361 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK 420
Query: 372 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 406
KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
Sbjct: 421 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR 455
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 313 bits (802), Expect = 2e-85
Identities = 178/439 (40%), Positives = 250/439 (56%), Gaps = 58/439 (13%)
Query: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
F +LG++ L E C QLG +PT +Q+ IP L+GRD +G A+TGSGKT AF LPIL
Sbjct: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
Query: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHI 145
L E P +F LVLTPTRELA+QI+EQF LG +G++ +IVGG+D ++Q+L L++KPH+
Sbjct: 64 LSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHV 123
Query: 146 IIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNM---DFETEVDKILKVIPRDRKTF 202
+IATPGRL DHL ++ F+++ +++LVMDEADR+L DF +++ IL +P R+T
Sbjct: 124 VIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTL 183
Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFK------------ 250
LFSAT+T +++LQ A P + TVE+L Q Y+ +P K K
Sbjct: 184 LFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQ 243
Query: 251 -----------------------------------------SKRLGSLNKFKAKARSILL 269
+R +L KFK+ IL+
Sbjct: 244 DEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILI 303
Query: 270 ATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRI 329
ATDVASRGLDIP V VV+N + P K YIHRVGRTARAGR G+AIT VTQYD+ L I
Sbjct: 304 ATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAI 363
Query: 330 EHLIGKKLPGFPTQDDEVMMLTERVAEAQRFA--RMELREHGEKKKRSREDAGDNDDTEG 387
E I KKL F ++ EV+ + +V +R ++E EKK+ ++ + +
Sbjct: 364 EEQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDP 423
Query: 388 AIGVRNKVAGGKMKKRKGR 406
+ + K K+K++ R
Sbjct: 424 DLEAKRKAELAKIKQKNRR 442
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 231 bits (588), Expect = 1e-60
Identities = 141/417 (33%), Positives = 221/417 (52%), Gaps = 55/417 (13%)
Query: 21 EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFAL 80
+E +F+D+ ++ L +A +G+ +PT IQ IP+ L G+DI A TG+GKT AFAL
Sbjct: 215 DENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFAL 274
Query: 81 PILNALLETPQRL---FALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSL 137
P+L L+ P++ LVL PTREL Q+ L + + + VGG+D SQ
Sbjct: 275 PVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEA 334
Query: 138 ALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPR 197
AL P I+IATPGRLIDHL N F+L +++ L++DEADR+L+ FE ++ +I+++
Sbjct: 335 ALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSH 394
Query: 198 DRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYI-------------- 243
R+T LFSATMT +V+ L +LKNPV+ V+S L+Q +I
Sbjct: 395 HRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIV 454
Query: 244 --------------FIPSKFKSKR------------------------LGSLNKFKAKAR 265
F +K ++ R L +L +FK +
Sbjct: 455 AALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQI 514
Query: 266 SILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVEL 325
IL+ATDVA+RGLDI V V+NF +P K Y+HRVGRTARAGR+G++++ V + + ++
Sbjct: 515 DILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKM 574
Query: 326 FQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSREDAGDN 382
+ I + D ++ +++ + ++ L+ E+K+ + +A N
Sbjct: 575 LKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQIN 631
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 219 bits (557), Expect = 5e-57
Identities = 138/394 (35%), Positives = 206/394 (52%), Gaps = 85/394 (21%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
+++KD + + E D+ G+ +PT IQ +AIP+ LQ RDIIG+AETGSGKT AF +P+L
Sbjct: 391 RSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLL 450
Query: 84 ---------NALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMS 134
+ + E+ Q +A++L PTRELA QI E+ G +G+++ ++GGI
Sbjct: 451 VWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISRED 510
Query: 135 QSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKV 194
Q L I+IATPGRLID LEN + L Y+V+DEADR+++M FE +V KIL+
Sbjct: 511 QGFRLRMGCEIVIATPGRLIDVLEN-RYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEH 569
Query: 195 IP--------------------------RDRKTFLFSATMTKKVQKLQRAALKNPVKCAV 228
+P + R+T +F+ATM V++L R+ L+ P +
Sbjct: 570 MPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYI 629
Query: 229 SSKYQTVEKLQQYYIFIPSKFKSKRL---------------------------------- 254
S + E+++Q + K K+L
Sbjct: 630 GSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGY 689
Query: 255 ---------------GSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYI 299
+L+ KA A+ IL+ATDVA RG+DI V +VVN+D+ + +DYI
Sbjct: 690 NACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYI 749
Query: 300 HRVGRTARAGRSGKAITFVTQYDVELFQRIEHLI 333
HR+GRT RAG+SG AITF+T+ D +F ++ I
Sbjct: 750 HRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAI 783
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 203 bits (516), Expect = 3e-52
Identities = 138/447 (30%), Positives = 221/447 (49%), Gaps = 76/447 (17%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
K++ G++ + + + G+ KPT IQ +AIP + GRD+IG+A+TGSGKT AF LP+
Sbjct: 372 KSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMF 431
Query: 84 NAL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLA 138
+ LE + A+++TPTRELA QI+++ + ++G++ + GG Q
Sbjct: 432 RHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAE 491
Query: 139 LAKKPHIIIATPGRLIDHLENTKG--FNLRALKYLVMDEADRILNMDFETEVDKILKVIP 196
L + II+ TPGR+ID L G NLR + Y+V+DEADR+ +M FE +V +I+ +
Sbjct: 492 LKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVR 551
Query: 197 RDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKSKRL-- 254
DR+T +FSAT + ++ L R L P++ V + ++Q I I + K +L
Sbjct: 552 PDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLE 611
Query: 255 --------GS----------------------------------------LNKFKAKARS 266
GS +N FK
Sbjct: 612 LLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCK 671
Query: 267 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ----YD 322
+L+AT VA+RGLD+ H+ +VVN+ P H +DY+HR GRT RAG G A TF+T+ Y
Sbjct: 672 LLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYA 731
Query: 323 VELFQRIEHLIGKKLP--------GFPTQDDEVMMLTERVA----EAQRFARMELREHGE 370
++ + +E L G +P F Q + ++ + + +F E E
Sbjct: 732 GDIIKALE-LSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANE 790
Query: 371 KKKRSREDAG--DNDDTEGAIGVRNKV 395
+KK + G D+DD + A+ + ++
Sbjct: 791 RKKLQKAALGLQDSDDEDAAVDIDEQI 817
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 198 bits (504), Expect = 6e-51
Identities = 132/416 (31%), Positives = 211/416 (50%), Gaps = 66/416 (15%)
Query: 18 VEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGA 77
+ E F D ++ + + + T+IQ + I LALQG+D++G A+TGSGKT A
Sbjct: 63 INVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLA 122
Query: 78 FALPILNALLE----TPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSM 133
F +P+L AL + L L+++PTRELA+Q E +G + + +I+GG D
Sbjct: 123 FLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 182
Query: 134 SQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILK 193
++ + +I++ TPGRL+ H++ T F+ L+ LV+DEADRIL+M F ++ +++
Sbjct: 183 HEAERI-NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIE 241
Query: 194 VIPRDRKTFLFSATMTKKVQKLQRAALKNP--VKCAVSSKYQTVEKLQQYYI-------- 243
+P+ R+T LFSAT TK V+ L R +LKNP V +KY T L+Q YI
Sbjct: 242 NLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKI 301
Query: 244 -----FIPSKFKSK--------------------------------------RLGSLNKF 260
F+ S K K R+ N+F
Sbjct: 302 SVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEF 361
Query: 261 KAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ 320
K ++L ATD+A+RGLD P V+ V+ FD P + YIHR GRTAR G+A+ +
Sbjct: 362 VRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLP 421
Query: 321 YDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSR 376
+ + ++ L+ KK+P E+ + E++ + Q+ L + + K+R++
Sbjct: 422 SEKAM---VQQLLQKKVP-----VKEIKINPEKLIDVQKKLESILAQDQDLKERAQ 469
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 193 bits (490), Expect = 3e-49
Identities = 122/354 (34%), Positives = 180/354 (50%), Gaps = 57/354 (16%)
Query: 25 TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84
+F G + L + +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF P+L
Sbjct: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
Query: 85 AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139
+ LE A+++ PTREL QI + + G + ++S + GG Q+ AL
Sbjct: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373
Query: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
+ I++ TPGRLIDH++ K NL+ + YLV DEADR+ +M FE +V I + DR
Sbjct: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432
Query: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKF------- 249
+T LFSAT KK++KL R L +P++ + E + Q + PSK+
Sbjct: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRL 492
Query: 250 -----------------------------------------KSKRLGSLNKFKAKARSIL 268
+S+R ++ FK K +L
Sbjct: 493 VEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVL 552
Query: 269 LATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 322
+ATDVA+RGLDIP + V+N+D+ + HR+GRT RAG G A T +T D
Sbjct: 553 VATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 193 bits (490), Expect = 3e-49
Identities = 122/354 (34%), Positives = 180/354 (50%), Gaps = 57/354 (16%)
Query: 25 TFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILN 84
+F G + L + +T+PT IQ + +P+AL GRD+IG+A+TGSGKT AF P+L
Sbjct: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 313
Query: 85 AL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL 139
+ LE A+++ PTREL QI + + G + ++S + GG Q+ AL
Sbjct: 314 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 373
Query: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
+ I++ TPGRLIDH++ K NL+ + YLV DEADR+ +M FE +V I + DR
Sbjct: 374 QEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDR 432
Query: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI---PSKF------- 249
+T LFSAT KK++KL R L +P++ + E + Q + PSK+
Sbjct: 433 QTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRL 492
Query: 250 -----------------------------------------KSKRLGSLNKFKAKARSIL 268
+S+R ++ FK K +L
Sbjct: 493 VEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVL 552
Query: 269 LATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYD 322
+ATDVA+RGLDIP + V+N+D+ + HR+GRT RAG G A T +T D
Sbjct: 553 VATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 190 bits (482), Expect = 2e-48
Identities = 141/397 (35%), Positives = 195/397 (49%), Gaps = 83/397 (20%)
Query: 44 WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
+T+PT IQ + PLAL GRD++G+A+TGSGKT A+ LP + LE LVL
Sbjct: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250
Query: 99 TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
PTRELA Q+ + + G ++S I GG Q L + I IATPGRLID LE
Sbjct: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310
Query: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
+ K NLR YLV+DEADR+L+M FE ++ KI+ I DR+T ++SAT K+V++L
Sbjct: 311 SGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 369
Query: 219 ALKNPVK--------------------CAVSSKYQTV---------EKLQQYYIFIPS-- 247
L++ + C S K + EK + IF+ +
Sbjct: 370 FLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKR 429
Query: 248 ----------------------KFKSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 285
K + +R LN+F++ IL+ATDVASRGLD+ V
Sbjct: 430 RCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKF 489
Query: 286 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDD 345
V+N+D P S+DY+HR+GRTAR+ G A TF T PG Q
Sbjct: 490 VINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT------------------PGNLKQAR 531
Query: 346 EVMMLTERVAEAQRFARMELREH------GEKKKRSR 376
E++ + E +A M+L +H G K RSR
Sbjct: 532 ELIKVLEEANQAINPKLMQLVDHRGGGGGGGKGGRSR 568
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 189 bits (480), Expect = 4e-48
Identities = 136/383 (35%), Positives = 190/383 (49%), Gaps = 77/383 (20%)
Query: 44 WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
+T+PT IQ + PLAL GRD++G+A+TGSGKT A+ LP + LE LVL
Sbjct: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250
Query: 99 TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
PTRELA Q+ + + G ++S I GG Q L + I IATPGRLID LE
Sbjct: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310
Query: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
+ K NLR YLV+DEADR+L+M FE ++ KI+ I DR+T ++SAT K+V++L
Sbjct: 311 SGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 369
Query: 219 ALKNPVK--------------------CAVSSKYQTV---------EKLQQYYIFIPS-- 247
L++ + C S K + EK + IF+ +
Sbjct: 370 FLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKR 429
Query: 248 ----------------------KFKSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 285
K + +R LN+F++ IL+ATDVASRGLD+ V
Sbjct: 430 RCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKF 489
Query: 286 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDD 345
V+N+D P S+DY+HR+GRTAR+ G A TF T PG Q
Sbjct: 490 VINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT------------------PGNLKQAR 531
Query: 346 EVMMLTERVAEAQRFARMELREH 368
E++ + E +A M+L +H
Sbjct: 532 ELIKVLEEANQAINPKLMQLVDH 554
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 184 bits (468), Expect = 1e-46
Identities = 125/339 (36%), Positives = 185/339 (54%), Gaps = 57/339 (16%)
Query: 31 VTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLET- 89
V + +A ++G+T T+IQ ++I L+GRD++ A+TGSGKT AF +P + +++
Sbjct: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 245
Query: 90 --PQR-LFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHII 146
P+ L+L+PTRELA Q + L + +I+GG + +++ L +II
Sbjct: 246 FMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINII 305
Query: 147 IATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSA 206
+ATPGRL+DH++NT GF + L+ LV+DEADRIL++ FE E+ +I+K++P R+T LFSA
Sbjct: 306 VATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSA 365
Query: 207 TMTKKVQKLQRAAL-KNPVKCAV--SSKYQTVEKLQQYYIFIPSK---------FKSKRL 254
T T+KV+ L R +L K P+ V TV+ L+Q Y+ PS+ K R
Sbjct: 366 TQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRK 425
Query: 255 GSLNKFKAKARSI----------------------------------------LLATDVA 274
L F + S+ LL TDVA
Sbjct: 426 KKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVA 485
Query: 275 SRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGK 313
+RGLDIP VD +V +D P K+YIHRVGRTAR G +G+
Sbjct: 486 ARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR-GLNGR 523
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 184 bits (468), Expect = 1e-46
Identities = 122/374 (32%), Positives = 193/374 (51%), Gaps = 58/374 (15%)
Query: 19 EEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAF 78
+++++ F+ +G++ + + + G+ PT IQ + IP+ L G+D++ +A TGSGKT F
Sbjct: 91 KKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACF 150
Query: 79 ALPILNAL----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMS 134
LP+ L +T R AL+L+PTRELA Q + + LG G+++A+I+GG
Sbjct: 151 LLPMFERLKTHSAQTGAR--ALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMED 208
Query: 135 QSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKV 194
Q AL + P IIIATPGRL+ H+ L++++Y+V DEADR+ M F ++ +I+
Sbjct: 209 QFAALHENPDIIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIAR 267
Query: 195 IPRDRKTFLFSATMTKKVQKLQRAALKNPV--KCAVSSK--------------------- 231
+P +T LFSAT+ K + + RA L PV + V +K
Sbjct: 268 LPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVL 327
Query: 232 ----YQTVEKLQQYYIFIPSKFKSKRLG------------------------SLNKFKAK 263
+ V Q +F+ +K ++ L +L KF
Sbjct: 328 LHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLG 387
Query: 264 ARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDV 323
S L+ TD+A+RGLDIP +D V+N+ P K ++HRVGR ARAGRSG A + V ++
Sbjct: 388 KCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEI 447
Query: 324 ELFQRIEHLIGKKL 337
+ +G+ L
Sbjct: 448 PYLLDLHLFLGRSL 461
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 184 bits (468), Expect = 1e-46
Identities = 122/374 (32%), Positives = 193/374 (51%), Gaps = 58/374 (15%)
Query: 19 EEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAF 78
+++++ F+ +G++ + + + G+ PT IQ + IP+ L G+D++ +A TGSGKT F
Sbjct: 91 KKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACF 150
Query: 79 ALPILNAL----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMS 134
LP+ L +T R AL+L+PTRELA Q + + LG G+++A+I+GG
Sbjct: 151 LLPMFERLKTHSAQTGAR--ALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMED 208
Query: 135 QSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKV 194
Q AL + P IIIATPGRL+ H+ L++++Y+V DEADR+ M F ++ +I+
Sbjct: 209 QFAALHENPDIIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIAR 267
Query: 195 IPRDRKTFLFSATMTKKVQKLQRAALKNPV--KCAVSSK--------------------- 231
+P +T LFSAT+ K + + RA L PV + V +K
Sbjct: 268 LPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVL 327
Query: 232 ----YQTVEKLQQYYIFIPSKFKSKRLG------------------------SLNKFKAK 263
+ V Q +F+ +K ++ L +L KF
Sbjct: 328 LHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLG 387
Query: 264 ARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDV 323
S L+ TD+A+RGLDIP +D V+N+ P K ++HRVGR ARAGRSG A + V ++
Sbjct: 388 KCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEI 447
Query: 324 ELFQRIEHLIGKKL 337
+ +G+ L
Sbjct: 448 PYLLDLHLFLGRSL 461
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 183 bits (465), Expect = 2e-46
Identities = 115/395 (29%), Positives = 193/395 (48%), Gaps = 58/395 (14%)
Query: 5 EEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDI 64
+E D + E + T TF +G+ + L G+ KP+ IQ AI ++GRD+
Sbjct: 19 KEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDV 78
Query: 65 IGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSA 124
I +++G+GKT F++ +L L + AL+L PTRELA QI + ALG + VQ
Sbjct: 79 IAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCH 138
Query: 125 VIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDF 184
+GG + L H++ TPGR+ D + + RA+K LV+DEAD +LN F
Sbjct: 139 ACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEMLNKGF 197
Query: 185 ETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYY-- 242
+ ++ + + +P + L SAT+ ++ ++ + +P++ V T+E ++Q++
Sbjct: 198 KEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVA 257
Query: 243 ------------------------IFIPSKFK------------------------SKRL 254
IF +K K +R
Sbjct: 258 VEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERE 317
Query: 255 GSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKA 314
+ +F++ A +L++TDV +RGLD+P V +++N+D+P + + YIHR+GR+ R GR G A
Sbjct: 318 SIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVA 377
Query: 315 ITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMM 349
I FV D+ + + IE + TQ DE+ M
Sbjct: 378 INFVKNDDIRILRDIEQY-------YSTQIDEMPM 405
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 182 bits (462), Expect = 5e-46
Identities = 137/397 (34%), Positives = 200/397 (50%), Gaps = 65/397 (16%)
Query: 37 EACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQ----- 91
E + G+ KPT IQ +A P+ LQG D+IG+A+TG+GKT + +P L+ P
Sbjct: 255 ENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQR 314
Query: 92 -RLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATP 150
R LVLTPTRELA Q+ + S G++S + GG + Q L K IIIATP
Sbjct: 315 NRPGMLVLTPTRELALQVEGEC-CKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATP 373
Query: 151 GRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTK 210
GRL D L+ + NL+ + YLV+DEAD++L+M FE ++ KIL + DR+T + SAT
Sbjct: 374 GRLND-LQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPH 432
Query: 211 KVQKLQRAALKNPV--------KCAVSSK-------------------YQTVEKLQQYYI 243
V +L ++ LK P+ AVSS Q++ + +
Sbjct: 433 SVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIV 492
Query: 244 FIPSKFKSKRLGS------------------------LNKFKAKARSILLATDVASRGLD 279
F+ K + L S L FK IL+ATD+ASRGLD
Sbjct: 493 FVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLD 552
Query: 280 IPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPG 339
+ V V NFD P + ++Y+HR+GRT RAGR+G +IT +T+ D + + +++ +
Sbjct: 553 VHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERANQS 612
Query: 340 FPTQDDEVMMLTERVAEAQRFARMEL---REHGEKKK 373
P +E++ + ER Q+ ME R G KK
Sbjct: 613 IP---EELVSMAERFKAHQQKREMERKMERPQGRPKK 646
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 181 bits (459), Expect = 1e-45
Identities = 118/359 (32%), Positives = 183/359 (50%), Gaps = 63/359 (17%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
K+FK++ + + G PT IQI+ IP L GRD+IG+A TGSGKT F LP++
Sbjct: 181 KSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVI 240
Query: 84 NALLETPQRL--------FALVLTPTRELAFQ---ISEQFEAL---GSSIGVQSAVIVGG 129
LE +RL + L++ P+RELA Q I E + L SS ++ A+ +GG
Sbjct: 241 MFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGG 300
Query: 130 IDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVD 189
+ Q + H+++ATPGRL+D L+ K +L +YL +DEADR+++M FE ++
Sbjct: 301 MSVKEQMETIRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFEGDIR 359
Query: 190 KILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAV--------------------- 228
I R+T LFSATM KK+Q ++AL PV V
Sbjct: 360 TIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEA 419
Query: 229 -------------------SSKYQTVEKLQQYYI--------FIPSKFKSKRLGSLNKFK 261
+ K V+ + +Y + K + +R ++ F+
Sbjct: 420 KMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFR 479
Query: 262 AKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ 320
+ +L+ATDVAS+GLD P + V+N+D+P ++Y+HR+GRT R+G +G A TF+ +
Sbjct: 480 EGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINK 538
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 181 bits (458), Expect = 1e-45
Identities = 119/368 (32%), Positives = 188/368 (51%), Gaps = 60/368 (16%)
Query: 12 EASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETG 71
E ++PI++ F+ + +VL + G+ PT IQ++ IP+ L GRDI+ A+TG
Sbjct: 197 EVTRPIID------FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTG 250
Query: 72 SGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGI 130
SGKT AF LP++ L + AL+LTPTRELA QI Q + L S + +++ ++VGG+
Sbjct: 251 SGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGL 310
Query: 131 DSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDK 190
Q L + +IIATPGRL+D ++ + L +K +V+DEAD +L M F+ +V
Sbjct: 311 PLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKMGFQQQVLD 369
Query: 191 ILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFK 250
IL+ IP D +T L SAT+ +++L L NPV+ K ++Q +++ K
Sbjct: 370 ILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAK 429
Query: 251 SKRLGSL-----------------------------------------NKFKAKARSIL- 268
K+L + K + + ++IL
Sbjct: 430 KKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILK 489
Query: 269 ----------LATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 318
++T V RGLD+ V +VVNFD+P+ +Y+H++GR R G++G AITF+
Sbjct: 490 GLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFI 549
Query: 319 TQYDVELF 326
LF
Sbjct: 550 NNNSKRLF 557
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 180 bits (456), Expect = 2e-45
Identities = 122/339 (35%), Positives = 174/339 (51%), Gaps = 59/339 (17%)
Query: 44 WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
+T+PT IQ + P+AL G D++G+A+TGSGKT ++ LP + LE LVL
Sbjct: 114 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173
Query: 99 TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
PTRELA Q+ + + ++S I GG Q L + I IATPGRLID LE
Sbjct: 174 APTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233
Query: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
K NLR YLV+DEADR+L+M FE ++ KI+ I DR+T ++SAT K+V++L
Sbjct: 234 CGKT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 292
Query: 219 ALKNPVKCAVSSKYQTV-----------------------------EKLQQYYIFIPSKF 249
LK+ + + + + EK + +F+ +K
Sbjct: 293 FLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKR 352
Query: 250 KSKRLGS------------------------LNKFKAKARSILLATDVASRGLDIPHVDV 285
+ L LN+FK IL+ATDVASRGLD+ V
Sbjct: 353 RCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKF 412
Query: 286 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVE 324
V+N+D P S+DYIHR+GRTAR+ ++G A TF T +++
Sbjct: 413 VINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIK 451
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 176 bits (445), Expect = 4e-44
Identities = 116/382 (30%), Positives = 196/382 (51%), Gaps = 54/382 (14%)
Query: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
F+D + L ++GW KP+ IQ E+IP+AL GRDI+ A+ G+GK+GA+ +P+L
Sbjct: 98 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157
Query: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKKPH 144
L + A+V+ PTRELA Q+S+ + + G + GG + + L H
Sbjct: 158 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 217
Query: 145 IIIATPGRLIDHLENTKGF-NLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFL 203
++IATPGR++D ++ KG + ++ +V+DEAD++L+ DF ++ I+ +P++R+ L
Sbjct: 218 VVIATPGRILDLIK--KGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILL 275
Query: 204 FSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFK------------- 250
+SAT VQK + L+ P + + + T++ + QYY ++ + K
Sbjct: 276 YSATFPLSVQKFMNSHLQKPYEINLMEEL-TLKGVTQYYAYVTERQKVHCLNTLFSRLQI 334
Query: 251 ---------SKRLGSLNK-----------FKAKARS----------------ILLATDVA 274
S+R+ L K AK R L+ TD+
Sbjct: 335 NQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLF 394
Query: 275 SRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIG 334
+RG+DI V+VV+NFD P ++ Y+HR+GR+ R G G AI +T D + IE +G
Sbjct: 395 TRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLG 454
Query: 335 KKLPGFPTQDDEVMMLTERVAE 356
++ P+ D+ + + E +E
Sbjct: 455 TEIKPIPSNIDKSLYVAEYHSE 476
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 175 bits (444), Expect = 6e-44
Identities = 119/382 (31%), Positives = 188/382 (49%), Gaps = 73/382 (19%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
++F D+ + +++ + +T+PT +Q AIP+ + RD++ A+TGSGKT AF LPIL
Sbjct: 180 ESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPIL 239
Query: 84 NALLET------------------PQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
+ + Q +LVL PTRELA QI E+ V+ V
Sbjct: 240 SQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 299
Query: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185
+ GG D Q L + H+++ATPGRL+D +E K L KYLV+DEADR+L+M FE
Sbjct: 300 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 358
Query: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241
++ +I++ + P+ R T +FSAT K++Q L R L + AV T E + Q
Sbjct: 359 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 418
Query: 242 YIFIPSKFKSK------------------------------------------------- 252
+++ K
Sbjct: 419 VVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 478
Query: 253 -RLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 311
R +L++F++ IL+AT VA+RGLDI +V V+NFD+P+ ++Y+HR+GRT R G
Sbjct: 479 DREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNL 538
Query: 312 GKAITFVTQYDVELFQRIEHLI 333
G A +F + ++ + + + L+
Sbjct: 539 GLATSFFNERNINITKDLLDLL 560
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 175 bits (444), Expect = 6e-44
Identities = 116/381 (30%), Positives = 194/381 (50%), Gaps = 58/381 (15%)
Query: 6 EHDSPTEASQP--IVEE---EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
EH P E P ++E E F D+ + + L G+ KP+ IQ AI ++
Sbjct: 11 EHGGP-EGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIK 69
Query: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
G D+I A++G+GKT FA+ IL L + ALVL PTRELA QI + ALG +G
Sbjct: 70 GYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMG 129
Query: 121 VQSAVIVGGIDSMSQSLAL-AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRI 179
+GG + ++ L A+ PHI++ TPGR+ D L N + + + +K V+DEAD +
Sbjct: 130 ATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDML-NRRYLSPKWIKMFVLDEADEM 188
Query: 180 LNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQ 239
L+ F+ ++ +I + + + L SATM V ++ + +++P++ V + T+E ++
Sbjct: 189 LSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIK 248
Query: 240 QYY--------------------------IFIPSKFK----------------------- 250
Q+Y IF+ ++ K
Sbjct: 249 QFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMD 308
Query: 251 -SKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAG 309
+R + +F++ + +L+ TD+ +RG+D+ V +V+N+D+PT+ ++YIHR+GR R G
Sbjct: 309 QKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFG 368
Query: 310 RSGKAITFVTQYDVELFQRIE 330
R G AI FVT+ D + + IE
Sbjct: 369 RKGVAINFVTEEDKRILRDIE 389
>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
sapiens]
Length = 600
Score = 173 bits (439), Expect = 2e-43
Identities = 119/350 (34%), Positives = 177/350 (50%), Gaps = 69/350 (19%)
Query: 38 ACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLF--- 94
A +LG+ T +Q IPL ++ +D+ A TGSGKT AF +PIL LL ++L
Sbjct: 23 ALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRREEKLKKSQ 82
Query: 95 --ALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKP--HIIIATP 150
A+++TPTRELA QI E S ++ G + + + K+ +II+ATP
Sbjct: 83 VGAIIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDVERFKQQGGNIIVATP 142
Query: 151 GRLIDHLEN-TKGFNL----RALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFS 205
GRL D +G +L R+L LV+DEADR+L+M FE ++ IL+ +P+ R+T LFS
Sbjct: 143 GRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFS 202
Query: 206 ATMTKKVQKLQRAALKNPVKCAV-------SSKYQTVEKLQQYYIF-------------- 244
AT T++V+ L RA L+NPV+ +V SS +T +L+ YY+
Sbjct: 203 ATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKADEKFNQLVHFL 262
Query: 245 ------------------------------------IPSKFKSKRLGSLNKFKAKARSIL 268
I K K KR +F+ IL
Sbjct: 263 RNHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIMCIHGKMKYKRNKIFMEFRKLQSGIL 322
Query: 269 LATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFV 318
+ TDV +RG+DIP V+ V+ +D P+++ ++HR GRTAR G G A+ F+
Sbjct: 323 VCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFL 372
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 172 bits (437), Expect = 4e-43
Identities = 110/372 (29%), Positives = 187/372 (50%), Gaps = 52/372 (13%)
Query: 21 EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFAL 80
E +F D+ +++ L G+ KP+ IQ AI ++G D+I A++G+GKT FA+
Sbjct: 29 EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAI 88
Query: 81 PILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL- 139
IL + + ALVL PTRELA QI + ALG +G +GG + ++ L
Sbjct: 89 SILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQ 148
Query: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199
+ PHII+ TPGR+ D L N + + + +K V+DEAD +L+ F+ ++ I + + +
Sbjct: 149 MEAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT 207
Query: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYY----------------- 242
+ L SATM V ++ + +++P++ V + T+E ++Q+Y
Sbjct: 208 QVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLY 267
Query: 243 ---------IFIPSKFK------------------------SKRLGSLNKFKAKARSILL 269
IFI ++ K +R + +F++ + +L+
Sbjct: 268 ETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLI 327
Query: 270 ATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRI 329
TD+ +RG+D+ V +V+N+D+PT+ ++YIHR+GR R GR G AI VT+ D + I
Sbjct: 328 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387
Query: 330 EHLIGKKLPGFP 341
E + P
Sbjct: 388 ETFYNTSIEEMP 399
>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 172 bits (436), Expect = 5e-43
Identities = 110/374 (29%), Positives = 186/374 (49%), Gaps = 55/374 (14%)
Query: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
F+D + L A G+ P+++Q E IP A+ G D++ A++G GKT F L L
Sbjct: 47 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106
Query: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK-P 143
L ++ LV+ TRELAFQIS+++E + V+ AV GG+ L K P
Sbjct: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166
Query: 144 HIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL-NMDFETEVDKILKVIPRDRKTF 202
HI++ TPGR++ L K NL+ +K+ ++DE D++L +D +V +I ++ P +++
Sbjct: 167 HIVVGTPGRIL-ALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVM 225
Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQ-TVEKLQQYYIFIPSKFKSK--------- 252
+FSAT++K+++ + R +++P++ V + + T+ LQQYY+ + K++
Sbjct: 226 MFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVL 285
Query: 253 ----------------------------------------RLGSLNKFKAKARSILLATD 272
RL +FK R IL+AT+
Sbjct: 286 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345
Query: 273 VASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT-QYDVELFQRIEH 331
+ RG+DI V++ N+D+P S Y+HRV R R G G AITFV+ + D ++ ++
Sbjct: 346 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405
Query: 332 LIGKKLPGFPTQDD 345
+ P + D
Sbjct: 406 RFEVNISELPDEID 419
>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 172 bits (436), Expect = 5e-43
Identities = 110/374 (29%), Positives = 186/374 (49%), Gaps = 55/374 (14%)
Query: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
F+D + L A G+ P+++Q E IP A+ G D++ A++G GKT F L L
Sbjct: 47 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106
Query: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK-P 143
L ++ LV+ TRELAFQIS+++E + V+ AV GG+ L K P
Sbjct: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166
Query: 144 HIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL-NMDFETEVDKILKVIPRDRKTF 202
HI++ TPGR++ L K NL+ +K+ ++DE D++L +D +V +I ++ P +++
Sbjct: 167 HIVVGTPGRIL-ALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVM 225
Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQ-TVEKLQQYYIFIPSKFKSK--------- 252
+FSAT++K+++ + R +++P++ V + + T+ LQQYY+ + K++
Sbjct: 226 MFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVL 285
Query: 253 ----------------------------------------RLGSLNKFKAKARSILLATD 272
RL +FK R IL+AT+
Sbjct: 286 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345
Query: 273 VASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT-QYDVELFQRIEH 331
+ RG+DI V++ N+D+P S Y+HRV R R G G AITFV+ + D ++ ++
Sbjct: 346 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405
Query: 332 LIGKKLPGFPTQDD 345
+ P + D
Sbjct: 406 RFEVNISELPDEID 419
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 172 bits (436), Expect = 5e-43
Identities = 118/382 (30%), Positives = 187/382 (48%), Gaps = 73/382 (19%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
+ F D+ + +++ + +T+PT +Q AIP+ RD++ A+TGSGKT AF LPIL
Sbjct: 178 ENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPIL 237
Query: 84 NALL------------------ETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
+ + Q +LVL PTRELA QI E+ V+ V
Sbjct: 238 SQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 297
Query: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185
+ GG D Q L + H+++ATPGRL+D +E K L KYLV+DEADR+L+M FE
Sbjct: 298 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 356
Query: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241
++ +I++ + P+ R T +FSAT K++Q L R L + AV T E + Q
Sbjct: 357 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 416
Query: 242 YIFIP--------------------------------------------------SKFKS 251
+++ + +
Sbjct: 417 VVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 476
Query: 252 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 311
R +L++F++ IL+AT VA+RGLDI +V V+NFD+P+ ++Y+HR+GRT R G
Sbjct: 477 DREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNL 536
Query: 312 GKAITFVTQYDVELFQRIEHLI 333
G A +F + ++ + + + L+
Sbjct: 537 GLATSFFNEKNMNITKDLLDLL 558
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 172 bits (436), Expect = 5e-43
Identities = 118/382 (30%), Positives = 187/382 (48%), Gaps = 73/382 (19%)
Query: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
+ F D+ + +++ + +T+PT +Q AIP+ RD++ A+TGSGKT AF LPIL
Sbjct: 178 ENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPIL 237
Query: 84 NALL------------------ETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
+ + Q +LVL PTRELA QI E+ V+ V
Sbjct: 238 SQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCV 297
Query: 126 IVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFE 185
+ GG D Q L + H+++ATPGRL+D +E K L KYLV+DEADR+L+M FE
Sbjct: 298 VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMGFE 356
Query: 186 TEVDKILK---VIPRD-RKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQY 241
++ +I++ + P+ R T +FSAT K++Q L R L + AV T E + Q
Sbjct: 357 PQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQK 416
Query: 242 YIFIP--------------------------------------------------SKFKS 251
+++ + +
Sbjct: 417 VVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQR 476
Query: 252 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 311
R +L++F++ IL+AT VA+RGLDI +V V+NFD+P+ ++Y+HR+GRT R G
Sbjct: 477 DREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNL 536
Query: 312 GKAITFVTQYDVELFQRIEHLI 333
G A +F + ++ + + + L+
Sbjct: 537 GLATSFFNEKNMNITKDLLDLL 558
>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
sapiens]
Length = 427
Score = 169 bits (428), Expect = 4e-42
Identities = 108/374 (28%), Positives = 188/374 (50%), Gaps = 55/374 (14%)
Query: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
F+D + L A G+ P+++Q E IP A+ G D++ A++G GKT F L L
Sbjct: 46 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 105
Query: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK-P 143
+ ++ LV+ TRELAFQIS+++E + V+ +V GG+ L K P
Sbjct: 106 IEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCP 165
Query: 144 HIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL-NMDFETEVDKILKVIPRDRKTF 202
H+++ TPGR++ + N + F+L+ +K+ V+DE D++L +D +V +I ++ P +++
Sbjct: 166 HVVVGTPGRILALVRN-RSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCM 224
Query: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQ-TVEKLQQYYIFIPSKFKSK--------- 252
+FSAT++K ++ + R +++P++ V + + T+ LQQYY+ + K++
Sbjct: 225 MFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVL 284
Query: 253 ----------------------------------------RLGSLNKFKAKARSILLATD 272
RL +FK R IL+AT+
Sbjct: 285 EFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATN 344
Query: 273 VASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT-QYDVELFQRIEH 331
+ RG+DI V++V N+D+P S Y+HRV R R G G AITFV+ + D ++ ++
Sbjct: 345 LFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 404
Query: 332 LIGKKLPGFPTQDD 345
+ P + D
Sbjct: 405 RFEVNVAELPEEID 418
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 164 bits (414), Expect = 2e-40
Identities = 130/396 (32%), Positives = 202/396 (51%), Gaps = 60/396 (15%)
Query: 35 LCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETP---- 90
L ++ ++G KPT IQ +A P+ LQG D+I +A+TG+GKT ++ +P L P
Sbjct: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISRE 292
Query: 91 QRLFA--LVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIA 148
QR LVLTPTRELA + + S G++S I GG + Q ++K IIIA
Sbjct: 293 QRNGPGMLVLTPTRELALHVEAECSKY-SYKGLKSICIYGGRNRNGQIEDISKGVDIIIA 351
Query: 149 TPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATM 208
TPGRL D L+ NLR++ YLV+DEAD++L+M+FE ++ KIL + DR+T + SAT
Sbjct: 352 TPGRLND-LQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATW 410
Query: 209 TKKVQKLQRAALKNPV--------KCAVSSKYQ----TVEK----LQQYYI--------- 243
V++L + LK+P+ AV++ Q T EK L Q ++
Sbjct: 411 PDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKV 470
Query: 244 --FIPSKFKSKRLGS------------------------LNKFKAKARSILLATDVASRG 277
F+ K + L S + FK+ IL+ TD+ SRG
Sbjct: 471 IMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRG 530
Query: 278 LDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKL 337
LD+ V V N+D P + Y+HRVG R G++G ++T +TQ D ++ + ++ +
Sbjct: 531 LDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRAN 590
Query: 338 PGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKK 373
P +D VM ++ + +R R+ G+++K
Sbjct: 591 QSVP-EDLVVMAEQYKLNQQKRHRETRSRKPGQRRK 625
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,873,006
Number of Sequences: 37866
Number of extensions: 569464
Number of successful extensions: 1804
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1563
Number of HSP's gapped (non-prelim): 140
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.