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Search of human proteins with 41327691
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
(1317 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 2561 0.0
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 545 e-154
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 540 e-153
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 533 e-151
gi|40254834 kinesin family member 1C [Homo sapiens] 498 e-140
gi|7661878 kinesin family member 14 [Homo sapiens] 496 e-140
gi|239756270 PREDICTED: StAR-related lipid transfer (START) doma... 495 e-139
gi|239750815 PREDICTED: StAR-related lipid transfer (START) doma... 495 e-139
gi|239745175 PREDICTED: StAR-related lipid transfer (START) doma... 495 e-139
gi|46852172 kinesin family member 13B [Homo sapiens] 486 e-137
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 479 e-135
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 479 e-135
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 479 e-135
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 479 e-135
gi|116686122 kinesin family member 4 [Homo sapiens] 311 2e-84
gi|150010604 kinesin family member 4B [Homo sapiens] 309 1e-83
gi|30794488 kinesin family member 27 [Homo sapiens] 305 1e-82
gi|46852174 kinesin family member 3A [Homo sapiens] 304 4e-82
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 295 3e-79
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 295 3e-79
gi|71061468 centromere protein E [Homo sapiens] 292 2e-78
gi|4758646 kinesin family member 3B [Homo sapiens] 290 8e-78
gi|9910266 kinesin family member 15 [Homo sapiens] 285 2e-76
gi|83716024 kinesin family member 21B [Homo sapiens] 283 1e-75
gi|38569484 kinesin family member 21A [Homo sapiens] 272 1e-72
gi|41352705 kinesin family member 3C [Homo sapiens] 264 4e-70
gi|4758650 kinesin family member 5C [Homo sapiens] 259 2e-68
gi|13699824 kinesin family member 11 [Homo sapiens] 257 6e-68
gi|45446749 kinesin family member 5A [Homo sapiens] 254 5e-67
gi|122937289 kinesin family member 18B [Homo sapiens] 249 2e-65
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 2561 bits (6638), Expect = 0.0
Identities = 1317/1317 (100%), Positives = 1317/1317 (100%)
Query: 1 MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDF 60
MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDF
Sbjct: 1 MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDF 60
Query: 61 SFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSG 120
SFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSG
Sbjct: 61 SFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSG 120
Query: 121 LIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKE 180
LIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKE
Sbjct: 121 LIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKE 180
Query: 181 GPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEM 240
GPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEM
Sbjct: 181 GPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEM 240
Query: 241 PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTL 300
PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTL
Sbjct: 241 PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTL 300
Query: 301 AKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIIN 360
AKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIIN
Sbjct: 301 AKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIIN 360
Query: 361 KPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTK 420
KPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTK
Sbjct: 361 KPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTK 420
Query: 421 EWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYV 480
EWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYV
Sbjct: 421 EWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYV 480
Query: 481 GRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAV 540
GRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAV
Sbjct: 481 GRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAV 540
Query: 541 ILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFER 600
ILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFER
Sbjct: 541 ILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFER 600
Query: 601 QQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKR 660
QQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKR
Sbjct: 601 QQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKR 660
Query: 661 RSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEK 720
RSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEK
Sbjct: 661 RSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEK 720
Query: 721 AEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLR 780
AEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLR
Sbjct: 721 AEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLR 780
Query: 781 RGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLE 840
RGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLE
Sbjct: 781 RGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLE 840
Query: 841 KDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEY 900
KDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEY
Sbjct: 841 KDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEY 900
Query: 901 RLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQ 960
RLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQ
Sbjct: 901 RLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQ 960
Query: 961 ANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQ 1020
ANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQ
Sbjct: 961 ANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQ 1020
Query: 1021 RHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYE 1080
RHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYE
Sbjct: 1021 RHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYE 1080
Query: 1081 VDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEG 1140
VDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEG
Sbjct: 1081 VDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEG 1140
Query: 1141 CSTSADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDA 1200
CSTSADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDA
Sbjct: 1141 CSTSADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDA 1200
Query: 1201 HFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKYAELAALEFPPKKLFGNKDERVIAER 1260
HFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKYAELAALEFPPKKLFGNKDERVIAER
Sbjct: 1201 HFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKYAELAALEFPPKKLFGNKDERVIAER 1260
Query: 1261 RSHLEKYLRDFFSVMLQSATSPLHINKVGLTLSKHTICEFSPFFKKGVFDYSSHGTG 1317
RSHLEKYLRDFFSVMLQSATSPLHINKVGLTLSKHTICEFSPFFKKGVFDYSSHGTG
Sbjct: 1261 RSHLEKYLRDFFSVMLQSATSPLHINKVGLTLSKHTICEFSPFFKKGVFDYSSHGTG 1317
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 545 bits (1403), Expect = e-154
Identities = 363/880 (41%), Positives = 499/880 (56%), Gaps = 123/880 (13%)
Query: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61
ASVKVAVRVRP N RE E+K IIQM+ + T+I N K P +E K+F++D+S
Sbjct: 4 ASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNP--------KEAPKSFSFDYS 55
Query: 62 FYS-ADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS- 119
++S + P + SQ V+ +G +++ AFEGYN C+FAYGQTG+GKSYTMMG +S
Sbjct: 56 YWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQ 115
Query: 120 -GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHP 178
G+IP++CE LF +IN+ +E S+ EVSY+EIY ERVRDLL K+ NLRVREHP
Sbjct: 116 AGIIPQLCEELFEKINDNCN-EEMSYSVEVSYMEIYCERVRDLLNPKNKG--NLRVREHP 172
Query: 179 KEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDS 238
GPYVEDLSK V +Y D+ +LMDAGN RT AAT MN+ SSRSHA+FTI FTQ K D+
Sbjct: 173 LLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDN 232
Query: 239 E--MPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDA 296
E + E VSKI LVDLAGSERAD+TGA G RLKEG NINKSL TLG VISALA++S+
Sbjct: 233 ETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKK- 291
Query: 297 ANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAK 356
KKK F+PYRDSVLTWLL+++LGGNS+T M+A +SPAD+NY ETLSTLRYA+RAK
Sbjct: 292 -----KKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAK 346
Query: 357 NIINKPTINEDANVKLIRELRAEIARLKTLL-AQG-------NQIALLDSPTALSME--- 405
I INED N KL+REL+ E+ RLK LL AQG + +L SP++ S+
Sbjct: 347 QIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQV 406
Query: 406 ----------------------EKLQQNEARVQELTKEWTNKWNETQNI-------LKEQ 436
E+L+++E + EL + W K +T+ I L E
Sbjct: 407 GLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEM 466
Query: 437 TLALRKEG--IGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLH 494
+A+R++G +GV + PHL+ +++D L + +LY++K+G T VG+ DA QDIVL
Sbjct: 467 GVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLS 526
Query: 495 GLDLESEHCIF----ENIGGT-VTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMF 549
G ++ EHCIF N G VTL P S+ VNG ++ + L G I++G+ ++F
Sbjct: 527 GAHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVF 586
Query: 550 RFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKL 609
RFNHP++A REK S S + T + E +++ ++
Sbjct: 587 RFNHPEQARAEREKTPSAETPSEPVDWTFAQR-----------------ELLEKQGIDMK 629
Query: 610 ESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKL 669
+ K ++EME K +K E + + +E QR + E ++KQ E+ RS E
Sbjct: 630 QEMEKRLQEMEILYKKEKEEADLL---LEQQRLDYESKLQALQKQVET---RSLAAET-- 681
Query: 670 KDLLAEKEKFEEERLREQQEIEL-----QKKRQEEETFLR--VQEELQRLKELN----NN 718
E+E+ EEE Q E EL +K + + T LR + LKE N
Sbjct: 682 ----TEEEEEEEEVPWTQHEFELAQWAFRKWKSHQFTSLRDLLWGNAVYLKEANAISVEL 737
Query: 719 EKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQL 778
+K +FQ D L + E+EK + V+ V +Q
Sbjct: 738 KKKVQFQFVLLTDTLYSPLPPELLPTEMEKTHEDRPFPRTVVAVE------------VQD 785
Query: 779 LRRGEVQW--VEEEKRDLEGIRESLLRVKEARAGGDEDGE 816
L+ G + +E+ K+ L+ +RE R E + ++ E
Sbjct: 786 LKNGATHYWSLEKLKQRLDLMREMYDRAGEMASSAQDESE 825
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 540 bits (1390), Expect = e-153
Identities = 331/777 (42%), Positives = 475/777 (61%), Gaps = 91/777 (11%)
Query: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61
ASVKVAVRVRP N RE ++K IIQM S TTI N K P +E K+F++D+S
Sbjct: 4 ASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQP--------KETPKSFSFDYS 55
Query: 62 FYS-ADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNS--GD 118
++S + +Y SQ+ V++ +G ++++ AFEGYN C+FAYGQTG+GKSYTMMG
Sbjct: 56 YWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQ 115
Query: 119 SGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHP 178
G+IP++CE LFSRIN+TT D S+ EVSY+EIY ERVRDLL K+ NLRVREHP
Sbjct: 116 QGIIPQLCEDLFSRINDTTN-DNMSYSVEVSYMEIYCERVRDLLNPKNKG--NLRVREHP 172
Query: 179 KEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDS 238
GPYVEDLSK V +Y D+++LMD+GN RT AAT MN+ SSRSHA+F I FTQ + D+
Sbjct: 173 LLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDA 232
Query: 239 E--MPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDA 296
E + E VSKI LVDLAGSERAD+TGA G RLKEG NINKSL TLG VISALA++
Sbjct: 233 ETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGP 292
Query: 297 ANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAK 356
KKK F+PYRDSVLTWLL+++LGGNS+T M+A +SPAD+NY ETLSTLRYA+RAK
Sbjct: 293 NKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAK 352
Query: 357 NIINKPTINEDANVKLIRELRAEIARLKTLL-AQG--------NQIA------------- 394
I INED N KLIREL+ E+ RL+ LL AQG N +
Sbjct: 353 QIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDMTNALVGMSPSSSLSALSS 412
Query: 395 -----------LLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNI-------LKEQ 436
+L +P + E+L++ E + EL + W K T+ I L E
Sbjct: 413 RAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEM 472
Query: 437 TLALRKEG--IGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLH 494
+A+R++G +GV + PHL+ +++D L + +LY++K+G T VGR+D QDIVL
Sbjct: 473 GVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDGERRQDIVLS 532
Query: 495 GLDLESEHCIF--ENIGGT---VTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMF 549
G ++ EHC+F ++ GG+ VTL P G+ VNG ++ E + L G I++G++++F
Sbjct: 533 GHFIKEEHCVFRSDSRGGSEAVVTLEPCEGADTYVNGKKVTEPSILRSGNRIIMGKSHVF 592
Query: 550 RFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKL 609
RFNHP++A R++R+ + D + ++ L L G++ +++ + L++L
Sbjct: 593 RFNHPEQA---RQERERTPCAETPAEPVDWAFAQREL----LEKQGIDMKQEMEQRLQEL 645
Query: 610 ESKRKLIEE-----MEEKQKSDKAELERMQQEV---------ETQRKETEIVQLQIRKQE 655
E + + E +E+++ +++LE +Q+++ E + + + VQ R+ E
Sbjct: 646 EDQYRREREEATYLLEQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECE 705
Query: 656 ESL---KRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEEL 709
+L ++ ++ L+DLL F L+E I ++ K++ + F+ + + L
Sbjct: 706 LALWAFRKWKWYQFTSLRDLLWGNAIF----LKEANAISVELKKKVQFQFVLLTDTL 758
Score = 31.2 bits (69), Expect = 6.9
Identities = 22/78 (28%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 673 LAEKEKFEEERLREQ--QEIELQKKRQEEE-TFLRVQEELQRLKELNNNEKAEKFQIFQE 729
L EK+ + ++ EQ QE+E Q +R+ EE T+L Q+ L +L +K + + E
Sbjct: 626 LLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDSRYYPE 685
Query: 730 LDQLQKEKDEQYAKLELE 747
+++ ++E +++ E E
Sbjct: 686 VNEEEEEPEDEVQWTERE 703
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 533 bits (1372), Expect = e-151
Identities = 407/1186 (34%), Positives = 613/1186 (51%), Gaps = 141/1186 (11%)
Query: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61
ASVKVAVRVRP N RE E+K IIQM+ + T+I N K P +E K+F++D+S
Sbjct: 4 ASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNP--------KEAPKSFSFDYS 55
Query: 62 FYS-ADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS- 119
++S + P + SQ V+ +G +++ AFEGYN C+FAYGQTG+GKSYTMMG +S
Sbjct: 56 YWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQ 115
Query: 120 -GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHP 178
G+IP++CE LF +IN+ +E S+ EVSY+EIY ERVRDLL K+ NLRVREHP
Sbjct: 116 AGIIPQLCEELFEKINDNCN-EEMSYSVEVSYMEIYCERVRDLLNPKNKG--NLRVREHP 172
Query: 179 KEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDS 238
GPYVEDLSK V +Y D+ +LMDAGN RT AAT MN+ SSRSHA+FTI FTQ K D+
Sbjct: 173 LLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDN 232
Query: 239 E--MPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDA 296
E + E VSKI LVDLAGSERAD+TGA G RLKEG NINKSL TLG VISALA++S+
Sbjct: 233 ETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKK- 291
Query: 297 ANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAK 356
KKK F+PYRDSVLTWLL+++LGGNS+T M+A +SPAD+NY ETLSTLRYA+RAK
Sbjct: 292 -----KKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAK 346
Query: 357 NIINKPTINEDANVKLIRELRAEIARLKTLL-AQG-------NQIALLDSPTALSME--- 405
I INED N KL+REL+ E+ RLK LL AQG + +L SP++ S+
Sbjct: 347 QIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQV 406
Query: 406 ----------------------EKLQQNEARVQELTKEWTNKWNETQNI-------LKEQ 436
E+L+++E + EL + W K +T+ I L E
Sbjct: 407 GLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEM 466
Query: 437 TLALRKEG--IGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLH 494
+A+R++G +GV + PHL+ +++D L + +LY++K+G T VG+ DA QDIVL
Sbjct: 467 GVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLS 526
Query: 495 GLDLESEHCIF----ENIGGT-VTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMF 549
G ++ EHCIF N G VTL P S+ VNG ++ + L G I++G+ ++F
Sbjct: 527 GAHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVF 586
Query: 550 RFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKL 609
RFNHP++A REK S S + T + E +++ ++
Sbjct: 587 RFNHPEQARAEREKTPSAETPSEPVDWTFAQR-----------------ELLEKQGIDMK 629
Query: 610 ESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKL 669
+ K ++EME K +K E + + +E QR + + ++S KR E
Sbjct: 630 QEMEKRLQEMEILYKKEKEEADLL---LEQQRLDAD-----SDSGDDSDKR---SCEESW 678
Query: 670 KDLLAEKEKFEEERLRE-QQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQ 728
K + + +EK +L+ ++ L ++ E ++ ++ + K K+
Sbjct: 679 KLITSLREKLPPSKLQTIVKKCGLPSSGKKREPI-----KMYQIPQRRRLSKDSKWVTIS 733
Query: 729 ELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVE 788
+L ++Q K+ Y ++ L R QE E + +V ++L R + V
Sbjct: 734 DL-KIQAVKEICY-EVALNDFRHSRQEIEALAIVK--MKELCAMYGKKDPNERDSWRAVA 789
Query: 789 EEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKD 848
+ D G+ + + A G D ++L K + E +++ K N++ + ++
Sbjct: 790 RDVWDTVGVGDEKIEDVMATGKGSTDVDDL-KVHIDKLEDILQEVKKQNNMKDEEIK--- 845
Query: 849 ILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQ 908
+L+ ++ + +++L + + K S K E V + K L +ER
Sbjct: 846 VLRNKMLKMEKVLPLIGSQEQK-SPGSHKAKEPVGAGVSSTSENNVSKGDNGELAKEERV 904
Query: 909 LQYLLQNHLPTL-------LEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQA 961
Q L N P + ++Q F+ L + ++ V E + ++
Sbjct: 905 SQ--LMNGDPAFRRGRLRWMRQEQIRFKNLQQQEITKQLRRQNVPHRFIPPENRKPRFPF 962
Query: 962 NANQLQK---------LQATFEFTANIARQEEKVRKKEKEILESREKQQREALERAL--- 1009
+N + + E ++++ RK KE ES+EK + A +
Sbjct: 963 KSNPKHRNSWSPGTHIIITEDEVIELRIPKDDEARKGNKE--ESQEKGGKGAFKDPQFPW 1020
Query: 1010 ----ARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQE 1065
R + ++H + + R + SLN+G + + QAS AE
Sbjct: 1021 GSQGMRSQDHIQVSKQHINNQQQPPQLRWRSNSLNNGQPKSTRCQASASAESLNSHSGHP 1080
Query: 1066 RLEYEIQQLKQKIYEVDGVQKDHH--GTLEGKVASSSLPVSAEKSH 1109
+ + Q K+ I++ +++ G LEG A+S + + SH
Sbjct: 1081 TADVQTFQAKRHIHQHRQSYCNYNTGGQLEGNAATSYQKQTDKPSH 1126
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 498 bits (1283), Expect = e-140
Identities = 307/717 (42%), Positives = 423/717 (58%), Gaps = 97/717 (13%)
Query: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61
ASVKVAVRVRP N RE +AK ++ M+ + T+I N K ++ K+FT+D+S
Sbjct: 4 ASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPK--------QSKDAPKSFTFDYS 55
Query: 62 FYS-ADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNS--GD 118
++S T+ P + SQ+ V++ +G +++ AFEGYN C+FAYGQTG+GKSYTMMG G
Sbjct: 56 YWSHTSTEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQ 115
Query: 119 SGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHP 178
G++P++CE LFSR++E + S+ EVSY+EIY ERVRDLL KS + LRVREHP
Sbjct: 116 QGIVPQLCEDLFSRVSENQS-AQLSYSVEVSYMEIYCERVRDLLNPKSRGS--LRVREHP 172
Query: 179 KEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD- 237
GPYV+DLSK V +Y D+ +LMD GN RT AAT MN+ SSRSHA+FTI FTQ D
Sbjct: 173 ILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQ 232
Query: 238 -SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDA 296
+ + E VSKI LVDLAGSERAD++GA G+RLKEG NINKSL TLG VISALAD+
Sbjct: 233 LTGLDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSK- 291
Query: 297 ANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAK 356
K+K F+PYRDSVLTWLLK++LGGNS+T MIA +SPAD+NY ETLSTLRYA+R K
Sbjct: 292 -----KRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTK 346
Query: 357 NIINKPTINEDANVKLIRELRAEIARLKTLL-AQGNQIALLD------------------ 397
I INED N +LIREL+ E+ARL+ LL AQG + L+
Sbjct: 347 QIRCNAIINEDPNARLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGALPAVSS 406
Query: 398 --------SPTALSME-------------------EKLQQNEARVQELTKEWTNKWNET- 429
SPT + E E+LQ+ E + EL + W K +T
Sbjct: 407 PPAPVSPSSPTTHNGELEPSFSPNTESQIGPEEAMERLQETEKIIAELNETWEEKLRKTE 466
Query: 430 ------QNILKEQTLALRKEG--IGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVG 481
+ +L E +A+R++G +GV + PHL+ +++D L + +LYH+K+G T VG
Sbjct: 467 ALRMEREALLAEMGVAVREDGGTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVG 526
Query: 482 RDDASTEQDIVLHGLDLESEHCIFENIGG-----TVTLIPLSGSQCSVNGVQIVEATHLN 536
+ D DI L G + +HC+F +I VTL P G++ VNG + E L
Sbjct: 527 QVD----MDIKLTGQFIREQHCLFRSIPQPDGEVVVTLEPCEGAETYVNGKLVTEPLVLK 582
Query: 537 QGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGL 596
G I++G+ ++FRFNHP E A+L +R D + +++ L + L
Sbjct: 583 SGNRIVMGKNHVFRFNHP-EQARLERERGVPPPPGPPSEPVDWNFAQKELLEQQGIDIKL 641
Query: 597 EFE----------RQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKE 643
E E R+++EE + L +++L + + SDK E + + + R++
Sbjct: 642 EMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGDDSDKRSCEESWRLISSLREQ 698
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 496 bits (1278), Expect = e-140
Identities = 307/760 (40%), Positives = 439/760 (57%), Gaps = 57/760 (7%)
Query: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61
+ V VAVRVRP +REK +A ++ M + T+ + ++ F YD S
Sbjct: 357 SQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEH----------PDTKQVYNFIYDVS 406
Query: 62 FYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGL 121
F+S D P Y SQ V++ L +++ AFEG+N C+FAYGQTGSGKSYTMMG S + G+
Sbjct: 407 FWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGI 466
Query: 122 IPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSS---KTFNLRVREHP 178
IPR CE LFS++ + E S+ E+S+ E+YNE++ DLL K + LRVREHP
Sbjct: 467 IPRFCEDLFSQVARK-QTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHP 525
Query: 179 KEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD- 237
GPYVE LS ++V +Y D++ ++ GN R TAATGMND SSRSH++FT+ TQ K +
Sbjct: 526 VYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEF 585
Query: 238 ---SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQ 294
E S+I+L+DLAGSER G RLKEG +INKSL+TLG VISAL++
Sbjct: 586 VEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQ-- 643
Query: 295 DAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANR 354
A ++ VF+PYR+SVLTWLLK+SLGGNSKT MIATISPA N ETLSTLRYAN+
Sbjct: 644 ------ANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQ 697
Query: 355 AKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQI----ALLDSPTALSMEEKLQQ 410
A+ I+N +NED N KLIREL+AEIA+LK I L S+ KL Q
Sbjct: 698 ARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQ 757
Query: 411 NEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIIL 470
E + E+ + W K+ + + ++T L+K GI +D+ LP+L+ +++D + ++L
Sbjct: 758 QERDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLL 817
Query: 471 YHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIV 530
Y +KEG T VG+ ++ DI L G+ + +HC +N GGTV++IP+ ++ VNG I+
Sbjct: 818 YMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHIL 877
Query: 531 EATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVM 590
E T L G ++LG + FRFNHP E K KR SG + S D ++ L
Sbjct: 878 EITVLRHGDRVILGGDHYFRFNHPVEVQK--GKRPSGRDTPISEGPKDFEFAKNELLMA- 934
Query: 591 LYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRK--ETEIVQ 648
QR +LE E K ++ EE + + E QQE+ +Q+ E++I
Sbjct: 935 -----------QRSQLE-AEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKA 982
Query: 649 LQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEE 708
L+ +EES +++ I N+ + + E+ E+ + +QEI + KKR E ET L ++
Sbjct: 983 LEAELREESQRKKMQEINNQKAN--HKIEELEKAKQHLEQEIYVNKKRLEMET-LATKQA 1039
Query: 709 LQ-------RLKELNNNEKAEKFQIFQELDQLQKEKDEQY 741
L+ R+ E EK + + Q L Q + +D+ +
Sbjct: 1040 LEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTF 1079
Score = 40.0 bits (92), Expect = 0.015
Identities = 90/438 (20%), Positives = 176/438 (40%), Gaps = 69/438 (15%)
Query: 655 EESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRL-- 712
EE+L + + +L +A+ + +L + + E+ K + + + E RL
Sbjct: 686 EETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCR 745
Query: 713 KELNNNEKA--EKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEE--Q 768
+E+ + ++ + E+ ++ KEK EQ K +L++ + ++ + HL
Sbjct: 746 QEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVN 805
Query: 769 LREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDED----GEELEKAQLR 824
L E ++ ++L L I+E V + + D G +
Sbjct: 806 LNEDPQLSEML--------------LYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCT 851
Query: 825 FFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEIL-----ECLKCEHDKESRLLEKHD 879
F + V K V K IL+ V + + + H E + ++
Sbjct: 852 IKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPS 911
Query: 880 ESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQ-RAFEILDRGPLSL 938
T ++E P+DFE + + +L ++ L ++E Q +A E + +G
Sbjct: 912 GRDTPISEGPKDFE----------FAKNELLMAQRSQLEAEIKEAQLKAKEEMMQG---- 957
Query: 939 DNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESRE 998
Q+ KEM ++E +Q A ++++ L+A +EE RKK +EI +
Sbjct: 958 ----IQIAKEMAQQELS-SQKAAYESKIKALEAEL--------REESQRKKMQEINNQKA 1004
Query: 999 KQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQE 1058
+ E LE+A LE+ ++ +E+E K A + R L E
Sbjct: 1005 NHKIEELEKAKQHLEQEIYVNKKR----LEMETLATKQALEDHSIRHARIL--------E 1052
Query: 1059 ALEKDQERLEYEIQQLKQ 1076
ALE +++++ E+Q L+Q
Sbjct: 1053 ALETEKQKIAKEVQILQQ 1070
>gi|239756270 PREDICTED: StAR-related lipid transfer (START) domain
containing 9 [Homo sapiens]
Length = 4614
Score = 495 bits (1275), Expect = e-139
Identities = 308/794 (38%), Positives = 462/794 (58%), Gaps = 100/794 (12%)
Query: 1 MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPE--GGTGDSGRERTKTFTY 58
MA+V+VAVRVRP+++RE + I++++ I NLK+ G GDS RE+ F +
Sbjct: 1 MANVQVAVRVRPLSKRETKEGGRIIVEVDGKVAKIRNLKVDNRPDGFGDS-REKVMAFGF 59
Query: 59 DFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGD 118
D+ ++S + + P Y SQ++VF+ LG +V+ +GYN C+FAYGQTGSGK+YTM+G
Sbjct: 60 DYCYWSVNPEDPQYASQDVVFQDLGMEVLSGVAKGYNICLFAYGQTGSGKTYTMLGTPAS 119
Query: 119 SGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSK-TFNLRVREH 177
GL PRICEGLF R + +S R +VS+LEIYNERVRDLL++ K ++ LRVREH
Sbjct: 120 VGLTPRICEGLFVREKDCASLP-SSCRIKVSFLEIYNERVRDLLKQSGQKKSYTLRVREH 178
Query: 178 PKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD 237
P+ GPYV+ LS+H+V NY V +L++ G NR TAAT +++ SSRSHAIFTI +TQA +
Sbjct: 179 PEMGPYVQGLSQHVVTNYKQVIQLLEEGIANRITAATHVHEASSRSHAIFTIHYTQAILE 238
Query: 238 SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQ--- 294
+ +P E SKI+LVDLAGSERAD + R+ EG NINKSLVTLG VIS LA SQ
Sbjct: 239 NNLPSEMASKINLVDLAGSERADPSYCKD-RIAEGANINKSLVTLGIVISTLAQNSQVFS 297
Query: 295 -----------------------DAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIM 331
++ ++Q ++PYRDSVLTWLLKDSLGGNSKTIM
Sbjct: 298 SCQSLNSSVSNGGDSGILSSPSGTSSGGAPSRRQSYIPYRDSVLTWLLKDSLGGNSKTIM 357
Query: 332 IATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGN 391
+A +T+STLRYA+ AKNIINKP +NE +R Q N
Sbjct: 358 VAITR-------QTMSTLRYASSAKNIINKPRVNE------VRPF------------QKN 392
Query: 392 QIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDS 451
+L D +++E + QNE +V +LTK+WT KWN+ Q +++ ++ + + GVV+DS
Sbjct: 393 FSSLSDE----NLKELVLQNELKVDQLTKDWTQKWNDWQALMEHYSVDINRRRAGVVIDS 448
Query: 452 ELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGT 511
LPHL+ ++DD+LSTG++LYHLK G +E +HC + G
Sbjct: 449 SLPHLMALEDDVLSTGVVLYHLK--------------------GQWIERDHCTITSACGV 488
Query: 512 VTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSS 571
V L P G++C+VNG ++ + L QGAVI LG+ FRFNHP EAA LR++R+ G ++
Sbjct: 489 VVLRPARGARCTVNGREVTASCRLTQGAVITLGKAQKFRFNHPAEAAVLRQRRQVGEAAA 548
Query: 572 FSLSMTDLSKSRENLSAVMLYNPGLEFERQQREEL--EKLESKRKLIEEMEEKQKSDKAE 629
S+ L + ++ + +P L ER+ EE E ++ R + + S +A+
Sbjct: 549 GRGSLEWLDLDGDLAASRLGLSPLLWKERRALEEQCDEDHQTPR-------DGETSHRAQ 601
Query: 630 LERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKD---LLAEKEKFEEERLRE 686
+++ Q VE R +I+ +IR +E L+ I ++K+ L +E + ++
Sbjct: 602 IQQQQSYVEDLRH--QILAEEIRAAKE-LEFDQAWISQQIKENQQCLLREETWLASLQQQ 658
Query: 687 QQEIELQKKRQEE----ETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYA 742
QQE ++ +K E + +L+ E+Q + + ++ Q+ + E++ +
Sbjct: 659 QQEDQVAEKELEASVALDAWLQTDPEIQPSPFVQSQKRVVHLQLLRRHTLRAAERNVRRK 718
Query: 743 KLELEKKRLEEQEK 756
K+ + +R+ ++++
Sbjct: 719 KVSFQLERIIKKQR 732
>gi|239750815 PREDICTED: StAR-related lipid transfer (START) domain
containing 9 [Homo sapiens]
Length = 4614
Score = 495 bits (1275), Expect = e-139
Identities = 308/794 (38%), Positives = 462/794 (58%), Gaps = 100/794 (12%)
Query: 1 MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPE--GGTGDSGRERTKTFTY 58
MA+V+VAVRVRP+++RE + I++++ I NLK+ G GDS RE+ F +
Sbjct: 1 MANVQVAVRVRPLSKRETKEGGRIIVEVDGKVAKIRNLKVDNRPDGFGDS-REKVMAFGF 59
Query: 59 DFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGD 118
D+ ++S + + P Y SQ++VF+ LG +V+ +GYN C+FAYGQTGSGK+YTM+G
Sbjct: 60 DYCYWSVNPEDPQYASQDVVFQDLGMEVLSGVAKGYNICLFAYGQTGSGKTYTMLGTPAS 119
Query: 119 SGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSK-TFNLRVREH 177
GL PRICEGLF R + +S R +VS+LEIYNERVRDLL++ K ++ LRVREH
Sbjct: 120 VGLTPRICEGLFVREKDCASLP-SSCRIKVSFLEIYNERVRDLLKQSGQKKSYTLRVREH 178
Query: 178 PKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD 237
P+ GPYV+ LS+H+V NY V +L++ G NR TAAT +++ SSRSHAIFTI +TQA +
Sbjct: 179 PEMGPYVQGLSQHVVTNYKQVIQLLEEGIANRITAATHVHEASSRSHAIFTIHYTQAILE 238
Query: 238 SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQ--- 294
+ +P E SKI+LVDLAGSERAD + R+ EG NINKSLVTLG VIS LA SQ
Sbjct: 239 NNLPSEMASKINLVDLAGSERADPSYCKD-RIAEGANINKSLVTLGIVISTLAQNSQVFS 297
Query: 295 -----------------------DAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIM 331
++ ++Q ++PYRDSVLTWLLKDSLGGNSKTIM
Sbjct: 298 SCQSLNSSVSNGGDSGILSSPSGTSSGGAPSRRQSYIPYRDSVLTWLLKDSLGGNSKTIM 357
Query: 332 IATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGN 391
+A +T+STLRYA+ AKNIINKP +NE +R Q N
Sbjct: 358 VAITR-------QTMSTLRYASSAKNIINKPRVNE------VRPF------------QKN 392
Query: 392 QIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDS 451
+L D +++E + QNE +V +LTK+WT KWN+ Q +++ ++ + + GVV+DS
Sbjct: 393 FSSLSDE----NLKELVLQNELKVDQLTKDWTQKWNDWQALMEHYSVDINRRRAGVVIDS 448
Query: 452 ELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGT 511
LPHL+ ++DD+LSTG++LYHLK G +E +HC + G
Sbjct: 449 SLPHLMALEDDVLSTGVVLYHLK--------------------GQWIERDHCTITSACGV 488
Query: 512 VTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSS 571
V L P G++C+VNG ++ + L QGAVI LG+ FRFNHP EAA LR++R+ G ++
Sbjct: 489 VVLRPARGARCTVNGREVTASCRLTQGAVITLGKAQKFRFNHPAEAAVLRQRRQVGEAAA 548
Query: 572 FSLSMTDLSKSRENLSAVMLYNPGLEFERQQREEL--EKLESKRKLIEEMEEKQKSDKAE 629
S+ L + ++ + +P L ER+ EE E ++ R + + S +A+
Sbjct: 549 GRGSLEWLDLDGDLAASRLGLSPLLWKERRALEEQCDEDHQTPR-------DGETSHRAQ 601
Query: 630 LERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKD---LLAEKEKFEEERLRE 686
+++ Q VE R +I+ +IR +E L+ I ++K+ L +E + ++
Sbjct: 602 IQQQQSYVEDLRH--QILAEEIRAAKE-LEFDQAWISQQIKENQQCLLREETWLASLQQQ 658
Query: 687 QQEIELQKKRQEE----ETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYA 742
QQE ++ +K E + +L+ E+Q + + ++ Q+ + E++ +
Sbjct: 659 QQEDQVAEKELEASVALDAWLQTDPEIQPSPFVQSQKRVVHLQLLRRHTLRAAERNVRRK 718
Query: 743 KLELEKKRLEEQEK 756
K+ + +R+ ++++
Sbjct: 719 KVSFQLERIIKKQR 732
>gi|239745175 PREDICTED: StAR-related lipid transfer (START) domain
containing 9 [Homo sapiens]
Length = 4614
Score = 495 bits (1275), Expect = e-139
Identities = 308/794 (38%), Positives = 462/794 (58%), Gaps = 100/794 (12%)
Query: 1 MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPE--GGTGDSGRERTKTFTY 58
MA+V+VAVRVRP+++RE + I++++ I NLK+ G GDS RE+ F +
Sbjct: 1 MANVQVAVRVRPLSKRETKEGGRIIVEVDGKVAKIRNLKVDNRPDGFGDS-REKVMAFGF 59
Query: 59 DFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGD 118
D+ ++S + + P Y SQ++VF+ LG +V+ +GYN C+FAYGQTGSGK+YTM+G
Sbjct: 60 DYCYWSVNPEDPQYASQDVVFQDLGMEVLSGVAKGYNICLFAYGQTGSGKTYTMLGTPAS 119
Query: 119 SGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSK-TFNLRVREH 177
GL PRICEGLF R + +S R +VS+LEIYNERVRDLL++ K ++ LRVREH
Sbjct: 120 VGLTPRICEGLFVREKDCASLP-SSCRIKVSFLEIYNERVRDLLKQSGQKKSYTLRVREH 178
Query: 178 PKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD 237
P+ GPYV+ LS+H+V NY V +L++ G NR TAAT +++ SSRSHAIFTI +TQA +
Sbjct: 179 PEMGPYVQGLSQHVVTNYKQVIQLLEEGIANRITAATHVHEASSRSHAIFTIHYTQAILE 238
Query: 238 SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQ--- 294
+ +P E SKI+LVDLAGSERAD + R+ EG NINKSLVTLG VIS LA SQ
Sbjct: 239 NNLPSEMASKINLVDLAGSERADPSYCKD-RIAEGANINKSLVTLGIVISTLAQNSQVFS 297
Query: 295 -----------------------DAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIM 331
++ ++Q ++PYRDSVLTWLLKDSLGGNSKTIM
Sbjct: 298 SCQSLNSSVSNGGDSGILSSPSGTSSGGAPSRRQSYIPYRDSVLTWLLKDSLGGNSKTIM 357
Query: 332 IATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGN 391
+A +T+STLRYA+ AKNIINKP +NE +R Q N
Sbjct: 358 VAITR-------QTMSTLRYASSAKNIINKPRVNE------VRPF------------QKN 392
Query: 392 QIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDS 451
+L D +++E + QNE +V +LTK+WT KWN+ Q +++ ++ + + GVV+DS
Sbjct: 393 FSSLSDE----NLKELVLQNELKVDQLTKDWTQKWNDWQALMEHYSVDINRRRAGVVIDS 448
Query: 452 ELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGT 511
LPHL+ ++DD+LSTG++LYHLK G +E +HC + G
Sbjct: 449 SLPHLMALEDDVLSTGVVLYHLK--------------------GQWIERDHCTITSACGV 488
Query: 512 VTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSS 571
V L P G++C+VNG ++ + L QGAVI LG+ FRFNHP EAA LR++R+ G ++
Sbjct: 489 VVLRPARGARCTVNGREVTASCRLTQGAVITLGKAQKFRFNHPAEAAVLRQRRQVGEAAA 548
Query: 572 FSLSMTDLSKSRENLSAVMLYNPGLEFERQQREEL--EKLESKRKLIEEMEEKQKSDKAE 629
S+ L + ++ + +P L ER+ EE E ++ R + + S +A+
Sbjct: 549 GRGSLEWLDLDGDLAASRLGLSPLLWKERRALEEQCDEDHQTPR-------DGETSHRAQ 601
Query: 630 LERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKD---LLAEKEKFEEERLRE 686
+++ Q VE R +I+ +IR +E L+ I ++K+ L +E + ++
Sbjct: 602 IQQQQSYVEDLRH--QILAEEIRAAKE-LEFDQAWISQQIKENQQCLLREETWLASLQQQ 658
Query: 687 QQEIELQKKRQEE----ETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYA 742
QQE ++ +K E + +L+ E+Q + + ++ Q+ + E++ +
Sbjct: 659 QQEDQVAEKELEASVALDAWLQTDPEIQPSPFVQSQKRVVHLQLLRRHTLRAAERNVRRK 718
Query: 743 KLELEKKRLEEQEK 756
K+ + +R+ ++++
Sbjct: 719 KVSFQLERIIKKQR 732
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 486 bits (1252), Expect = e-137
Identities = 322/834 (38%), Positives = 459/834 (55%), Gaps = 63/834 (7%)
Query: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTIT--NLKIPEGGTGDSGRERTKTFTYD 59
+ VKVAVR+RPMNRRE DL K ++ ++ +K + N + +G R + K F YD
Sbjct: 4 SKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKG----DARGQPKVFAYD 59
Query: 60 FSFYSADTKSPD-YVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGD 118
F+S D + Y Q++VFK LG +++++AF+GYNAC+FAYGQTGSGKSYTMMG +
Sbjct: 60 HCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQ 119
Query: 119 SGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHP 178
GLIPR+C GLF R + +E SF+ EVSY+EIYNE+VRDLL K S+ L+VREH
Sbjct: 120 PGLIPRLCSGLFERTQKEEN-EEQSFKVEVSYMEIYNEKVRDLLDPKGSRQ-TLKVREHS 177
Query: 179 KEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD- 237
GPYV+ LSK V +Y D+E LM GN +RT AAT MN+ SSRSHA+F I T +D
Sbjct: 178 VLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDV 237
Query: 238 -SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDA 296
S E V K+ LVDLAGSERA TGA G RLKEG NINKSL TLG VISALAD S
Sbjct: 238 KSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSA-- 295
Query: 297 ANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAK 356
K K FVPYRDSVLTWLLKDSLGGNSKT M+AT+SPA NY ETLSTLRYA+RAK
Sbjct: 296 ----GKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAK 351
Query: 357 NIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQ 416
+I+N +NED N ++IR+LR E+ +L+ Q+ ++ + ++++L+++E +Q
Sbjct: 352 HIVNHAVVNEDPNARIIRDLREEVEKLR------EQLTKAEAMKSPELKDRLEESEKLIQ 405
Query: 417 ELTKEWTNKWNETQNILKEQTLALRKEGI-----GVVLDSELPHLIGIDDDLLSTGIILY 471
E+T W K +T+ I +E+ L GI G+ + + L+ ++ D +++Y
Sbjct: 406 EMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVY 465
Query: 472 HLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFE-NIGGTVTLIPLSGSQCSVNGVQIV 530
+LKE T +G ++ QDI L G+ + EHCI + G V L P ++ VNG +
Sbjct: 466 YLKE-HTLIG---SANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVS 521
Query: 531 EATHLNQGAVILLGRTNMFRFNHPKEAAKLR---EKRKSGLLSSFSLSMTDL-SKSRENL 586
L+ G IL G + FR N PK+ K E + + + S D+ S +
Sbjct: 522 SPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEV 581
Query: 587 SAVMLYN---PGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKE 643
S+ + +N +E + + ++S +E+ E++K E +R+ E E ++
Sbjct: 582 SSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLR 641
Query: 644 TEIVQLQIRKQE-ESLKRRSFH---IENKLKDLLAEKEKFEEE---RLREQ--------Q 688
+L KQ S+ R SFH + +L+ E+E RLREQ +
Sbjct: 642 R---RLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVR 698
Query: 689 EIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEK 748
E + ++ T +V ++ L+ N K + +K K +Q LE
Sbjct: 699 EANYIAEELDKRTEYKVTLQIP-ASSLDANRKRGSLLSEPAIQVRRKGKGKQIWSLEKLD 757
Query: 749 KRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLL 802
RL + L +E + + +R + + E+E L G+ L
Sbjct: 758 NRLLDMRD----LYQEWKECEEDNPVIRSYFKRADPFYDEQENHSLIGVANVFL 807
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 479 bits (1234), Expect = e-135
Identities = 344/935 (36%), Positives = 505/935 (54%), Gaps = 95/935 (10%)
Query: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFY 63
VKVAVRVRPMNRRE +L K +++ME ++T L P T R+ K F +D+ F+
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTV---LHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 64 SAD-TKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLI 122
S D + + Y QE+VFK LG +++ AF+GYNAC+FAYGQTGSGKS++MMG++ GLI
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQLGLI 122
Query: 123 PRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGP 182
PR+C LF RI+ + +F+ EVSY+EIYNE+VRDLL K S+ +L+VREH GP
Sbjct: 123 PRLCCALFKRISLEQN-ESQTFKVEVSYMEIYNEKVRDLLDPKGSRQ-SLKVREHKVLGP 180
Query: 183 YVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD--SEM 240
YV+ LS+ V ++ D+E LM GN +RT AAT MN+ SSRSHA+F I TQ +D S
Sbjct: 181 YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGN 240
Query: 241 PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTL 300
E VSK+ LVDLAGSER TGA G RLKEG NINKSL TLG VIS+LAD
Sbjct: 241 SGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD------QAA 294
Query: 301 AKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIIN 360
K K FVPYRDSVLTWLLKD+LGGNS+T MIATISPA NY ETLSTLRYA+RAK I+N
Sbjct: 295 GKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVN 354
Query: 361 KPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTK 420
+NED N K+IRELR E+ +L+ L+Q ++ A ++EKL+++E ++ELT
Sbjct: 355 HAVVNEDPNAKVIRELREEVEKLREQLSQA------EAMKAPELKEKLEESEKLIKELTV 408
Query: 421 EWTNKWNETQNILKEQTLALRKEGI-----GVVLDSELPHLIGIDDDLLSTGIILYHLKE 475
W K +T+ I +E+ L GI G+ + + +L+ ++ D +++Y+LK+
Sbjct: 409 TWEEKLRKTEEIAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLVYYLKD 468
Query: 476 GQTYVGRDDASTEQDIVLHGLDLESEHCIFENIG-GTVTLIPLSGSQCSVNGVQIVEATH 534
T VG D T QDI L G+ ++ +HC + G VTL P ++ VNG + T
Sbjct: 469 -HTRVGAD---TSQDIQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLVCSTTQ 524
Query: 535 LNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSM----TDLSKSRENLSAVM 590
L G IL G + FR N PK +++ L F DL + E S
Sbjct: 525 LWHGDRILWGNNHFFRINLPK-------RKRRDWLKDFEKETGPPEHDLDAASEASS--- 574
Query: 591 LYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQR--KETEIVQ 648
P +E Q E + K + ++ + Q +K LE + +E QR E E+ Q
Sbjct: 575 --EPDYNYEFAQMEVIMKTLNSNDPVQNV--VQVLEKQYLEEKRSALEEQRLMYERELEQ 630
Query: 649 LQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEE 708
L +Q+ S R+ ++ D LA + ++++ + E ++ ++ +++E+
Sbjct: 631 L---RQQLSPDRQP---QSSGPDRLAYSSQTAQQKVTQWAE---ERDELFRQSLAKLREQ 681
Query: 709 LQRLKEL--NNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKR-----------LEEQE 755
L + L N AE+ +L Q A L +KR + +
Sbjct: 682 LVKANTLVREANFLAEE---MSKLTDYQVTLQIPAANLSANRKRGAIVSEPAIQVRRKGK 738
Query: 756 KEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEE--EKRDLEGIRESLLRVKEARAGGDE 813
QV + LE +L + +++ Q +W E+ E + L G R EA+ +
Sbjct: 739 STQVWTIEKLENKLIDMRDLYQ-------EWKEKVPEAKRLYGKRGD--PFYEAQENHNL 789
Query: 814 DGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQ--KDILKKEVQEEQEILECLKCEHDKE 871
G + F + K + V +++ + ++ + ++++ + ++E E+ E
Sbjct: 790 IGVANVFLECLFCDVKLQYAVPIISQQGEVAGRLHVEVMRVTGAVPERVVEDDSSENSSE 849
Query: 872 SRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKE 906
S LE D S + ++K + R++ KE
Sbjct: 850 SGSLEVVDSS-------GEIIHRVKKLTCRVKIKE 877
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 479 bits (1234), Expect = e-135
Identities = 344/935 (36%), Positives = 505/935 (54%), Gaps = 95/935 (10%)
Query: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFY 63
VKVAVRVRPMNRRE +L K +++ME ++T L P T R+ K F +D+ F+
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTV---LHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 64 SAD-TKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLI 122
S D + + Y QE+VFK LG +++ AF+GYNAC+FAYGQTGSGKS++MMG++ GLI
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQLGLI 122
Query: 123 PRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGP 182
PR+C LF RI+ + +F+ EVSY+EIYNE+VRDLL K S+ +L+VREH GP
Sbjct: 123 PRLCCALFKRISLEQN-ESQTFKVEVSYMEIYNEKVRDLLDPKGSRQ-SLKVREHKVLGP 180
Query: 183 YVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD--SEM 240
YV+ LS+ V ++ D+E LM GN +RT AAT MN+ SSRSHA+F I TQ +D S
Sbjct: 181 YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGN 240
Query: 241 PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTL 300
E VSK+ LVDLAGSER TGA G RLKEG NINKSL TLG VIS+LAD
Sbjct: 241 SGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD------QAA 294
Query: 301 AKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIIN 360
K K FVPYRDSVLTWLLKD+LGGNS+T MIATISPA NY ETLSTLRYA+RAK I+N
Sbjct: 295 GKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVN 354
Query: 361 KPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTK 420
+NED N K+IRELR E+ +L+ L+Q ++ A ++EKL+++E ++ELT
Sbjct: 355 HAVVNEDPNAKVIRELREEVEKLREQLSQA------EAMKAPELKEKLEESEKLIKELTV 408
Query: 421 EWTNKWNETQNILKEQTLALRKEGI-----GVVLDSELPHLIGIDDDLLSTGIILYHLKE 475
W K +T+ I +E+ L GI G+ + + +L+ ++ D +++Y+LK+
Sbjct: 409 TWEEKLRKTEEIAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLVYYLKD 468
Query: 476 GQTYVGRDDASTEQDIVLHGLDLESEHCIFENIG-GTVTLIPLSGSQCSVNGVQIVEATH 534
T VG D T QDI L G+ ++ +HC + G VTL P ++ VNG + T
Sbjct: 469 -HTRVGAD---TSQDIQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLVCSTTQ 524
Query: 535 LNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSM----TDLSKSRENLSAVM 590
L G IL G + FR N PK +++ L F DL + E S
Sbjct: 525 LWHGDRILWGNNHFFRINLPK-------RKRRDWLKDFEKETGPPEHDLDAASEASS--- 574
Query: 591 LYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQR--KETEIVQ 648
P +E Q E + K + ++ + Q +K LE + +E QR E E+ Q
Sbjct: 575 --EPDYNYEFAQMEVIMKTLNSNDPVQNV--VQVLEKQYLEEKRSALEEQRLMYERELEQ 630
Query: 649 LQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEE 708
L +Q+ S R+ ++ D LA + ++++ + E ++ ++ +++E+
Sbjct: 631 L---RQQLSPDRQP---QSSGPDRLAYSSQTAQQKVTQWAE---ERDELFRQSLAKLREQ 681
Query: 709 LQRLKEL--NNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKR-----------LEEQE 755
L + L N AE+ +L Q A L +KR + +
Sbjct: 682 LVKANTLVREANFLAEE---MSKLTDYQVTLQIPAANLSANRKRGAIVSEPAIQVRRKGK 738
Query: 756 KEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEE--EKRDLEGIRESLLRVKEARAGGDE 813
QV + LE +L + +++ Q +W E+ E + L G R EA+ +
Sbjct: 739 STQVWTIEKLENKLIDMRDLYQ-------EWKEKVPEAKRLYGKRGD--PFYEAQENHNL 789
Query: 814 DGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQ--KDILKKEVQEEQEILECLKCEHDKE 871
G + F + K + V +++ + ++ + ++++ + ++E E+ E
Sbjct: 790 IGVANVFLECLFCDVKLQYAVPIISQQGEVAGRLHVEVMRVTGAVPERVVEDDSSENSSE 849
Query: 872 SRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKE 906
S LE D S + ++K + R++ KE
Sbjct: 850 SGSLEVVDSS-------GEIIHRVKKLTCRVKIKE 877
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 479 bits (1234), Expect = e-135
Identities = 344/935 (36%), Positives = 505/935 (54%), Gaps = 95/935 (10%)
Query: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFY 63
VKVAVRVRPMNRRE +L K +++ME ++T L P T R+ K F +D+ F+
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTV---LHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 64 SAD-TKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLI 122
S D + + Y QE+VFK LG +++ AF+GYNAC+FAYGQTGSGKS++MMG++ GLI
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQLGLI 122
Query: 123 PRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGP 182
PR+C LF RI+ + +F+ EVSY+EIYNE+VRDLL K S+ +L+VREH GP
Sbjct: 123 PRLCCALFKRISLEQN-ESQTFKVEVSYMEIYNEKVRDLLDPKGSRQ-SLKVREHKVLGP 180
Query: 183 YVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD--SEM 240
YV+ LS+ V ++ D+E LM GN +RT AAT MN+ SSRSHA+F I TQ +D S
Sbjct: 181 YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGN 240
Query: 241 PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTL 300
E VSK+ LVDLAGSER TGA G RLKEG NINKSL TLG VIS+LAD
Sbjct: 241 SGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD------QAA 294
Query: 301 AKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIIN 360
K K FVPYRDSVLTWLLKD+LGGNS+T MIATISPA NY ETLSTLRYA+RAK I+N
Sbjct: 295 GKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVN 354
Query: 361 KPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTK 420
+NED N K+IRELR E+ +L+ L+Q ++ A ++EKL+++E ++ELT
Sbjct: 355 HAVVNEDPNAKVIRELREEVEKLREQLSQA------EAMKAPELKEKLEESEKLIKELTV 408
Query: 421 EWTNKWNETQNILKEQTLALRKEGI-----GVVLDSELPHLIGIDDDLLSTGIILYHLKE 475
W K +T+ I +E+ L GI G+ + + +L+ ++ D +++Y+LK+
Sbjct: 409 TWEEKLRKTEEIAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLVYYLKD 468
Query: 476 GQTYVGRDDASTEQDIVLHGLDLESEHCIFENIG-GTVTLIPLSGSQCSVNGVQIVEATH 534
T VG D T QDI L G+ ++ +HC + G VTL P ++ VNG + T
Sbjct: 469 -HTRVGAD---TSQDIQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLVCSTTQ 524
Query: 535 LNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSM----TDLSKSRENLSAVM 590
L G IL G + FR N PK +++ L F DL + E S
Sbjct: 525 LWHGDRILWGNNHFFRINLPK-------RKRRDWLKDFEKETGPPEHDLDAASEASS--- 574
Query: 591 LYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQR--KETEIVQ 648
P +E Q E + K + ++ + Q +K LE + +E QR E E+ Q
Sbjct: 575 --EPDYNYEFAQMEVIMKTLNSNDPVQNV--VQVLEKQYLEEKRSALEEQRLMYERELEQ 630
Query: 649 LQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEE 708
L +Q+ S R+ ++ D LA + ++++ + E ++ ++ +++E+
Sbjct: 631 L---RQQLSPDRQP---QSSGPDRLAYSSQTAQQKVTQWAE---ERDELFRQSLAKLREQ 681
Query: 709 LQRLKEL--NNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKR-----------LEEQE 755
L + L N AE+ +L Q A L +KR + +
Sbjct: 682 LVKANTLVREANFLAEE---MSKLTDYQVTLQIPAANLSANRKRGAIVSEPAIQVRRKGK 738
Query: 756 KEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEE--EKRDLEGIRESLLRVKEARAGGDE 813
QV + LE +L + +++ Q +W E+ E + L G R EA+ +
Sbjct: 739 STQVWTIEKLENKLIDMRDLYQ-------EWKEKVPEAKRLYGKRGD--PFYEAQENHNL 789
Query: 814 DGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQ--KDILKKEVQEEQEILECLKCEHDKE 871
G + F + K + V +++ + ++ + ++++ + ++E E+ E
Sbjct: 790 IGVANVFLECLFCDVKLQYAVPIISQQGEVAGRLHVEVMRVTGAVPERVVEDDSSENSSE 849
Query: 872 SRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKE 906
S LE D S + ++K + R++ KE
Sbjct: 850 SGSLEVVDSS-------GEIIHRVKKLTCRVKIKE 877
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 479 bits (1234), Expect = e-135
Identities = 344/935 (36%), Positives = 505/935 (54%), Gaps = 95/935 (10%)
Query: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFY 63
VKVAVRVRPMNRRE +L K +++ME ++T L P T R+ K F +D+ F+
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTV---LHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 64 SAD-TKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLI 122
S D + + Y QE+VFK LG +++ AF+GYNAC+FAYGQTGSGKS++MMG++ GLI
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQLGLI 122
Query: 123 PRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGP 182
PR+C LF RI+ + +F+ EVSY+EIYNE+VRDLL K S+ +L+VREH GP
Sbjct: 123 PRLCCALFKRISLEQN-ESQTFKVEVSYMEIYNEKVRDLLDPKGSRQ-SLKVREHKVLGP 180
Query: 183 YVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD--SEM 240
YV+ LS+ V ++ D+E LM GN +RT AAT MN+ SSRSHA+F I TQ +D S
Sbjct: 181 YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGN 240
Query: 241 PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTL 300
E VSK+ LVDLAGSER TGA G RLKEG NINKSL TLG VIS+LAD
Sbjct: 241 SGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD------QAA 294
Query: 301 AKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIIN 360
K K FVPYRDSVLTWLLKD+LGGNS+T MIATISPA NY ETLSTLRYA+RAK I+N
Sbjct: 295 GKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVN 354
Query: 361 KPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTK 420
+NED N K+IRELR E+ +L+ L+Q ++ A ++EKL+++E ++ELT
Sbjct: 355 HAVVNEDPNAKVIRELREEVEKLREQLSQA------EAMKAPELKEKLEESEKLIKELTV 408
Query: 421 EWTNKWNETQNILKEQTLALRKEGI-----GVVLDSELPHLIGIDDDLLSTGIILYHLKE 475
W K +T+ I +E+ L GI G+ + + +L+ ++ D +++Y+LK+
Sbjct: 409 TWEEKLRKTEEIAQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLVYYLKD 468
Query: 476 GQTYVGRDDASTEQDIVLHGLDLESEHCIFENIG-GTVTLIPLSGSQCSVNGVQIVEATH 534
T VG D T QDI L G+ ++ +HC + G VTL P ++ VNG + T
Sbjct: 469 -HTRVGAD---TSQDIQLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLVCSTTQ 524
Query: 535 LNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSM----TDLSKSRENLSAVM 590
L G IL G + FR N PK +++ L F DL + E S
Sbjct: 525 LWHGDRILWGNNHFFRINLPK-------RKRRDWLKDFEKETGPPEHDLDAASEASS--- 574
Query: 591 LYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQR--KETEIVQ 648
P +E Q E + K + ++ + Q +K LE + +E QR E E+ Q
Sbjct: 575 --EPDYNYEFAQMEVIMKTLNSNDPVQNV--VQVLEKQYLEEKRSALEEQRLMYERELEQ 630
Query: 649 LQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEE 708
L +Q+ S R+ ++ D LA + ++++ + E ++ ++ +++E+
Sbjct: 631 L---RQQLSPDRQP---QSSGPDRLAYSSQTAQQKVTQWAE---ERDELFRQSLAKLREQ 681
Query: 709 LQRLKEL--NNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKR-----------LEEQE 755
L + L N AE+ +L Q A L +KR + +
Sbjct: 682 LVKANTLVREANFLAEE---MSKLTDYQVTLQIPAANLSANRKRGAIVSEPAIQVRRKGK 738
Query: 756 KEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEE--EKRDLEGIRESLLRVKEARAGGDE 813
QV + LE +L + +++ Q +W E+ E + L G R EA+ +
Sbjct: 739 STQVWTIEKLENKLIDMRDLYQ-------EWKEKVPEAKRLYGKRGD--PFYEAQENHNL 789
Query: 814 DGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQ--KDILKKEVQEEQEILECLKCEHDKE 871
G + F + K + V +++ + ++ + ++++ + ++E E+ E
Sbjct: 790 IGVANVFLECLFCDVKLQYAVPIISQQGEVAGRLHVEVMRVTGAVPERVVEDDSSENSSE 849
Query: 872 SRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKE 906
S LE D S + ++K + R++ KE
Sbjct: 850 SGSLEVVDSS-------GEIIHRVKKLTCRVKIKE 877
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 311 bits (798), Expect = 2e-84
Identities = 295/1053 (28%), Positives = 499/1053 (47%), Gaps = 143/1053 (13%)
Query: 54 KTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMM 113
K+FTYDF F + QE VF T ++K F+GYNA V AYGQTGSGK+Y+M
Sbjct: 47 KSFTYDFVFDPS-------TEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMG 99
Query: 114 G-------NSGDSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKS 166
G N G+IPR+ + LF I++ + ++ F +VSYLEIYNE + DLL
Sbjct: 100 GAYTAEQENEPTVGVIPRVIQLLFKEIDKKSDFE---FTLKVSYLEIYNEEILDLLCPSR 156
Query: 167 SKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAI 226
K + +RE PKEG + L++ V D ++ GN +RT A+T MN SSRSHAI
Sbjct: 157 EKA-QINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAI 215
Query: 227 FTIKFTQAKFDSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVI 286
FTI Q K S+ SK+HLVDLAGSER T A G RLKEG NIN+ L+ LGNVI
Sbjct: 216 FTISLEQRK-KSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVI 274
Query: 287 SALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETL 346
SAL D KK FVPYRDS LT LL+DSLGGNS T+MIA +SPAD N ETL
Sbjct: 275 SALGD----------DKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETL 324
Query: 347 STLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPT---ALS 403
+TLRYA+RA+ I NKP +N D + L+ ++ +L+ LL Q + L S T + +
Sbjct: 325 NTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSEN 384
Query: 404 MEEKLQQNEARVQE---LTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGID 460
++ +++N++ V+E L++ + +T +L+ L E ++++L L
Sbjct: 385 LQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILT---EQANEKMNAKLEEL---- 437
Query: 461 DDLLSTGIILYHLKEGQTYVGRDDASTEQDI-----VLHGLDLESEHCIFENIGGTVTLI 515
R A+ + D+ L +L+ I N+ +T +
Sbjct: 438 ---------------------RQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQL 476
Query: 516 PLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLS 575
C + T + Q A + E + + + +L
Sbjct: 477 SDETVACMAAAID----TAVEQEAQV--------------ETSPETSRSSDAFTTQHALR 518
Query: 576 MTDLSKSRENLSAVMLYNPGLEFERQQRE-ELEKLESK-RKLIEEMEEKQKSDKAELERM 633
+SK L+ + L + Q + +L+ ++ + + I+E+E + + + E E +
Sbjct: 519 QAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEEL 578
Query: 634 QQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQ 693
E++T +K+ +L R+ ++R +E ++ DL +++L EQ ++ L+
Sbjct: 579 VLELQTAKKDANQAKLSERR-----RKRLQELEGQIADL--------KKKLNEQSKL-LK 624
Query: 694 KKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEE 753
K E T ++ +E++ +K ++ Q+ +++ + ++ + K + E +L+E
Sbjct: 625 LKESTERTVSKLNQEIRMMKN-------QRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKE 677
Query: 754 QEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKR---DLEGIRESLLRVKEARAG 810
+++++ + LE R Q+ +LRR + KR L+ RE + KE ++
Sbjct: 678 RDRKRQYELLKLE---RNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSR 734
Query: 811 GDEDGEELEKAQLRFFEFKRRQLVKLVNLEK------DLVQQKDILKKEVQEEQEILECL 864
G +E R + ++ +V+ E+ DL++ + IL ++V + +E E
Sbjct: 735 G------MEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESG 788
Query: 865 KCEHDKESRLLEKHDESVTDVTEVPQDFEK-IKPVEYRLQYKERQLQYLLQNHLPTLLEE 923
+ K R E V+E K I+ +E ++++ Q+ L Q L
Sbjct: 789 ENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDA---- 844
Query: 924 KQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQE 983
E DR +N +E + K + + ++ Q+ KL+++ + +
Sbjct: 845 -----ESEDRPKQRWENIATILEAKCALK-YLIGELVSSKIQVSKLESSLKQSKTSCADM 898
Query: 984 EKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGS 1043
+K+ +E+ E + L+ L R+E++H + ++ + +K +
Sbjct: 899 QKMLFEERNHFAEIETE----LQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSE 954
Query: 1044 REQSGLQASLEAEQEALEKDQERLEYEIQQLKQ 1076
+EQ L ++L+ + E LEK +E E Q L++
Sbjct: 955 KEQQ-LLSTLKCQDEELEKMREVCEQNQQLLRE 986
Score = 78.6 bits (192), Expect = 4e-14
Identities = 115/500 (23%), Positives = 220/500 (44%), Gaps = 66/500 (13%)
Query: 599 ERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESL 658
+ Q +EL +L L E + K + ++L+ +Q + + KE E+ + ++K++E L
Sbjct: 519 QAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEEL 578
Query: 659 KRRSFHIENKLKDLLAEKEKFEEERLREQQEIE-----LQKKRQEEETFLRVQEELQR-L 712
++ KD A + K E R + QE+E L+KK E+ L+++E +R +
Sbjct: 579 V---LELQTAKKD--ANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTV 633
Query: 713 KELNNNEKAEKFQIFQELDQLQK--EKDEQYA-KLELEKKRLEEQEKEQVMLVAHLEEQL 769
+LN + K Q Q + Q+++ EK Q+ K + E +L+E+++++ + LE
Sbjct: 634 SKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLE--- 690
Query: 770 REKQEMIQLLRRGEVQWVEEEKR---DLEGIRESLLRVKEARAGGDEDGEELEKAQLRFF 826
R Q+ +LRR + KR L+ RE + KE ++ G +E R
Sbjct: 691 RNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRG------MEGTAARVK 744
Query: 827 EFKRRQLVKLVNLEK------DLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDE 880
+ ++ +V+ E+ DL++ + IL ++V + +E E + K R E
Sbjct: 745 NWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTE 804
Query: 881 SVTDVTEVPQDFEK-IKPVEYRLQYKERQLQYLLQNHLPTLLEEK-----QRAFEILDR- 933
V+E K I+ +E ++++ Q+ L Q L E++ + IL+
Sbjct: 805 VRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAK 864
Query: 934 -GPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKL---------QATFEFTANIARQE 983
L L + ++ + E L Q + + +QK+ + E A + R E
Sbjct: 865 CALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRME 924
Query: 984 EKVRKK--------------EKEILES---REKQQREALERALARLERRHSALQRHSTLG 1026
++ ++K EK++ ES +E+Q L+ LE+ +++ L
Sbjct: 925 QQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLL 984
Query: 1027 MEIEEQRQKLASLNSGSREQ 1046
E E +QKL L SR++
Sbjct: 985 RENEIIKQKLTLLQVASRQK 1004
Score = 37.4 bits (85), Expect = 0.096
Identities = 62/301 (20%), Positives = 135/301 (44%), Gaps = 37/301 (12%)
Query: 610 ESKRKLIEEMEEKQ--KSDKAELERMQQEVET-----QRKETEIVQL--QIRKQEESLKR 660
E+KR L + +E+++ D A+L+ ++ E +R+ + ++ Q+ + E+S+ +
Sbjct: 759 EAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITK 818
Query: 661 RSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEK 720
+ +E +++ A+ +++ L + E + +Q E + E LK L
Sbjct: 819 QIESLETEMEFRSAQIADLQQKLLDAESE---DRPKQRWENIATILEAKCALKYLIGELV 875
Query: 721 AEKFQIFQELDQLQKEKD---EQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQ 777
+ K Q+ + L++ K + L E+ E E E + +E+Q +EK ++
Sbjct: 876 SSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEK--VLY 933
Query: 778 LLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLV 837
LL + + + E++ + E + E ++ D EELEK +R + +QL++
Sbjct: 934 LLSQLQQSQMAEKQLE-ESVSEKEQQLLSTLKCQD---EELEK--MREVCEQNQQLLR-- 985
Query: 838 NLEKDLVQQKDILKKEVQEEQEILECLKCEHD----------KESRLLEKHDESVTDVTE 887
E ++++QK L + ++ + + D K SR+ EK E D+ +
Sbjct: 986 --ENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPKPKPSRVKEKFLEQSMDIED 1043
Query: 888 V 888
+
Sbjct: 1044 L 1044
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 309 bits (791), Expect = 1e-83
Identities = 312/1109 (28%), Positives = 518/1109 (46%), Gaps = 180/1109 (16%)
Query: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFY 63
V+VA+R RP+ +E + + +T + GT K+FTYDF F
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVV------GTD-------KSFTYDFVFD 56
Query: 64 SADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMG-------NS 116
QE VF ++K F+GYNA V AYGQTGSGK+Y+M G N
Sbjct: 57 PC-------TEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENE 109
Query: 117 GDSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVRE 176
G+IPR+ + LF I++ + ++ F +VSYLEIYNE + DLL K + +RE
Sbjct: 110 PTVGIIPRVIQLLFKEIDKKSDFE---FTLKVSYLEIYNEEILDLLCPSREKA-QINIRE 165
Query: 177 HPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKF 236
PKEG + L++ V D ++ GN +RT A+T MN SSRSHAIFTI Q K
Sbjct: 166 DPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK- 224
Query: 237 DSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDA 296
S+ C SK+HLVDLAGSER T A G RLKEG NIN+ L+ LGNVISAL D
Sbjct: 225 KSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD----- 279
Query: 297 ANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAK 356
KK FVPYRDS LT LL+DSLGGNS T+MIA +SPAD N ETLSTLRYA+RA+
Sbjct: 280 -----DKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRAR 334
Query: 357 NIINKPTINEDANVKLIRELRAEIARLKTLLAQ---GNQIALLDSPTALSMEEKLQQNEA 413
I NKP +N D + + L+ ++ +L+ LL Q G +++ + +++ +++N++
Sbjct: 335 KIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQS 394
Query: 414 RVQE---LTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIIL 470
V+E L++ + +T +L+ L E + L+++L L ++ + L
Sbjct: 395 LVEENEKLSRCLSKAAGQTAQMLERIILT---EQVNEKLNAKLEEL----RQHVACKLDL 447
Query: 471 YHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIV 530
L E L +L+ I N+ +T + C+ +
Sbjct: 448 QKLVE----------------TLEDQELKENVEIICNLQQLITQLSDETVACTAAAID-- 489
Query: 531 EATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVM 590
T + + A + E + + + +L +SK L+ +
Sbjct: 490 --TAVEEEAQV--------------ETSPETSRSSDAFTTQHALHQAQMSKEVVELNNAL 533
Query: 591 LYNPGLEFERQQRE-ELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQL 649
L + Q + +L+ ++ + ++ K+ + E+ +Q+E KE + +L
Sbjct: 534 ALKEALVRKMTQNDNQLQPIQF------QYQDNIKNLELEVINLQKE-----KEELVREL 582
Query: 650 QIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEEL 709
Q K+ + + S H L++L E Q +L+KK E+ L+++E
Sbjct: 583 QTAKKNVNQAKLSEHRHKLLQEL-------------EGQIADLKKKLNEQSKLLKLKEST 629
Query: 710 QRLKELNNNE----KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHL 765
+R N E K ++ Q+ +++ + ++ + K + E +L+E+++++ + L
Sbjct: 630 ERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKL 689
Query: 766 EEQLREKQEMIQLLRRGEVQWVEEEKR---DLEGIRESLLRVKEARAGGDED-------- 814
E R Q+ +LRR + KR L+ RE + KE ++ G E
Sbjct: 690 E---RNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNW 746
Query: 815 -GEELEKAQLRFFEFKRRQLVKLVN----LEKDLVQQKDILKKEVQEE--QEILECLKCE 867
G E+E + E +R L L+ L +D+VQ K+ KKE +E ++ +C
Sbjct: 747 LGNEIE--VMVSTEEAKRHLNDLLEDRKILAQDVVQLKE--KKESRENPPPKLRKCTFSL 802
Query: 868 HDKESRLLEKHDESVTDVTEVPQDFE----KIKPVEYRL---QYKERQLQYLLQNHLPTL 920
+ ++LE D + + + E +I ++ +L + ++R Q ++ T+
Sbjct: 803 SEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQ--CWENIATI 860
Query: 921 LEEKQRAFEILDRGPLS------LDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFE 974
LE K ++ S L+N+L Q + + ++ L + Q + ++++ E
Sbjct: 861 LEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIET-----E 915
Query: 975 FTANIARQEEKVRKK--------------EKEILES---REKQQREALERALARLERRHS 1017
A + R E++ ++K EK++ +S +E+Q L+ LE+
Sbjct: 916 LQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMRE 975
Query: 1018 ALQRHSTLGMEIEEQRQKLASLNSGSREQ 1046
+++ L E E +QKL L SR++
Sbjct: 976 VCEQNQQLLQENEIIKQKLILLQVASRQK 1004
Score = 51.2 bits (121), Expect = 6e-06
Identities = 82/410 (20%), Positives = 180/410 (43%), Gaps = 64/410 (15%)
Query: 577 TDLSKSRENLSAVMLYNPGLEFERQQREELEKL----ESKRKLIEEMEEKQKSDKAELER 632
T+ + S+ N M+ N ++ RQ +E+ EK + K K + +++E+ + + EL +
Sbjct: 629 TERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLK 688
Query: 633 MQQEVETQ----RKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQ- 687
+++ + Q R++TE ++ +++L+++ + +K K+ + ++ R+R
Sbjct: 689 LERNFQKQSSVLRRKTEEAAAANKRLKDALQKQR-EVTDKRKETQSHGKEGIAARVRNWL 747
Query: 688 -QEIELQKKRQEEETFLR--------VQEELQRLKELNNNE-----KAEKF--------- 724
EIE+ +E + L + +++ +LKE + K K
Sbjct: 748 GNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHG 807
Query: 725 QIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGE- 783
Q+ + D + K+ + ++EL ++ + + Q +L A E++ ++ E I + +
Sbjct: 808 QVLESEDCITKQIESLETEMELRSAQIADLQ--QKLLDAESEDRPKQCWENIATILEAKC 865
Query: 784 -----VQWVEEEKRDLEGIRESLLRVK-----------EARAGGDEDGEELEKAQLRFFE 827
+ + K + + SL + K E + E EL+ +R +
Sbjct: 866 ALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQ 925
Query: 828 FKRRQLVKLVN-LEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVT 886
+ +++ LV+ L++ + +K + K ++EQ+++ L+C+ ++ LEK E
Sbjct: 926 QHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEE----LEKMREVCEQNQ 981
Query: 887 EVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPT-LLEEKQRAFEILDRGP 935
++ Q+ E IK LQ R Q HLP L +FE + P
Sbjct: 982 QLLQENEIIKQKLILLQVASR------QKHLPNDTLLSPDSSFEYIPPKP 1025
Score = 44.7 bits (104), Expect = 6e-04
Identities = 87/488 (17%), Positives = 206/488 (42%), Gaps = 70/488 (14%)
Query: 707 EELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLE 766
EE ++L + + Q+ + + ++ ++ AKLE ++ + + Q ++ +
Sbjct: 397 EENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLED 456
Query: 767 EQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFF 826
++L+E E+I L++ Q +E ++ + +EA+ + A
Sbjct: 457 QELKENVEIICNLQQLITQLSDETVACTAAAIDTAVE-EEAQVETSPETSRSSDAFTTQH 515
Query: 827 EFKRRQLVK-LVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLE--------K 877
+ Q+ K +V L L ++ +++K Q + + L+ ++ ++ + LE +
Sbjct: 516 ALHQAQMSKEVVELNNALALKEALVRKMTQNDNQ-LQPIQFQYQDNIKNLELEVINLQKE 574
Query: 878 HDESVTDVTEVPQDFEKIKPVEYR---LQYKERQLQYLL-----QNHLPTLLEEKQRAFE 929
+E V ++ ++ + K E+R LQ E Q+ L Q+ L L E +R
Sbjct: 575 KEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVS 634
Query: 930 ILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKK 989
L++ + N Q+ ++M+E E+ Q++ ++ + + +E+ RK+
Sbjct: 635 KLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDK------------EVIQLKERDRKR 682
Query: 990 EKEILESREKQQREA------LERALARLERRHSALQRHSTLGMEIEEQRQKLASLNS-- 1041
+ E+L+ Q+++ E A A +R ALQ+ E+ ++R++ S
Sbjct: 683 QYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQ----REVTDKRKETQSHGKEG 738
Query: 1042 -GSREQSGLQASLE---AEQEA------LEKDQERLEYEIQQLKQK-------------- 1077
+R ++ L +E + +EA L +D++ L ++ QLK+K
Sbjct: 739 IAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKC 798
Query: 1078 ---IYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLH 1134
+ EV G + + ++ S + + + L ++A E+ ++ +++
Sbjct: 799 TFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIA 858
Query: 1135 RVISEGCS 1142
++ C+
Sbjct: 859 TILEAKCA 866
Score = 36.2 bits (82), Expect = 0.21
Identities = 53/254 (20%), Positives = 104/254 (40%), Gaps = 33/254 (12%)
Query: 493 LHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQG-------AVILLGR 545
+HG LESE CI + I T + L +Q + ++++A ++ A IL +
Sbjct: 805 VHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIATILEAK 864
Query: 546 TNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLY---NPGLEFERQQ 602
+ ++K+ + L S D+ K ML+ N E E +
Sbjct: 865 CALKYLIGELVSSKIHVTKLENSLRQSKASCADMQK--------MLFEEQNHFSEIETEL 916
Query: 603 REELEKLESKRK-----LIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEES 657
+ EL ++E + + L+ +++E Q ++K Q E KE ++V + EE
Sbjct: 917 QAELVRMEQQHQEKVLYLVSQLQESQMAEK------QLEKSASEKEQQLVSTLQCQDEEL 970
Query: 658 LKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNN 717
K R +N + LL E E +++ + Q + ++K +T L + +
Sbjct: 971 EKMREVCEQN--QQLLQENEIIKQKLILLQ--VASRQKHLPNDTLLSPDSSFEYIPPKPK 1026
Query: 718 NEKAEKFQIFQELD 731
+ ++ + Q +D
Sbjct: 1027 PSRVKEKFLEQSMD 1040
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 305 bits (782), Expect = 1e-82
Identities = 353/1307 (27%), Positives = 575/1307 (43%), Gaps = 223/1307 (17%)
Query: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFY 63
VKVAVR+RP+ +E + +++ IP GR+R FT+DF F
Sbjct: 6 VKVAVRIRPLLCKEALHNHQVCVRV-----------IPNSQQVIIGRDRV--FTFDFVFG 52
Query: 64 SADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGN------SG 117
T Q+ V+ T +V S EGYNA VFAYGQTGSGK+YT+ G G
Sbjct: 53 KNST-------QDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEG 105
Query: 118 DSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREH 177
G+IPR + +F I+E D F +VSY+E+Y E +RDLL ++S +L +RE
Sbjct: 106 QKGIIPRAIQEIFQSISEHPSID---FNVKVSYIEVYKEDLRDLLELETSMK-DLHIRED 161
Query: 178 PKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD 237
K + + V++ G+V L++ GN R T T MN+ SSRSHAIFTI Q +
Sbjct: 162 EKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKN 221
Query: 238 SEM--------PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISAL 289
E P VSK H VDLAGSER TG TG R KE IN L+ LGNVISAL
Sbjct: 222 MEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISAL 281
Query: 290 ADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTL 349
D ++K +PYRD+ +T LLKDSLGG++KT+MI +SP+ N+ E+L++L
Sbjct: 282 GD---------PRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSL 332
Query: 350 RYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLL-------AQGNQIALLDSPTA- 401
+YANRA+NI NKPT+N I E+ EI L+ L +Q QI SP
Sbjct: 333 KYANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTN 392
Query: 402 --LSMEEKLQQ-----------------------NEARVQELTKEWTNKW-NETQNILKE 435
S+EE++ Q + R+ E + +W N Q + K
Sbjct: 393 RIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKA 452
Query: 436 QTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDD-ASTEQDIVLH 494
+ R G L+ H+ + + LK+ Q + D+ ++++ +
Sbjct: 453 VLTSFRGIGGTASLEEGPQHVTVLQ--------LKRELKKCQCVLAADEVVFNQKELEVK 504
Query: 495 GLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQ---IVEATHLNQGAVILLGRTNMFRF 551
L + + + EN G V+L VN +Q I+E L L + N+
Sbjct: 505 ELKNQVQMMVQENKGHAVSLKEAQ----KVNRLQNEKIIEQQLLVDQLSEELTKLNLSVT 560
Query: 552 NHPKE------AAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFER----- 600
+ KE A++ E+R + L SR++ V P +R
Sbjct: 561 SSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGF 620
Query: 601 --QQREELEKLESKRKLI----------EEMEEKQKSDKAELERMQQEVETQRKETEIVQ 648
+ + L +E + K++ EE E ++KS R + Q+ ++
Sbjct: 621 RTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSG----TRCRSRSWIQKPDSVCSL 676
Query: 649 LQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEE 708
+++ ++ ++ E+ D L E ++ ++L+ + I + K++ E + ++ +
Sbjct: 677 VELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMK 736
Query: 709 LQRLKEL---NNNEKAEKFQIFQELDQLQKEKDEQYAKLEL-----EKKRLEEQEKEQVM 760
+KEL N+ K+ Q ++ +L E D + AK+EL + + LE ++ V
Sbjct: 737 EDLIKELIKTGNDAKSVSKQYSLKVTKL--EHDAEQAKVELIETQKQLQELENKDLSDVA 794
Query: 761 LVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEK 820
+ L+++ R+K + +L VQ ++++++D + + SL E RA E + K
Sbjct: 795 MKVKLQKEFRKKMDAAKL----RVQVLQKKQQDSKKL-ASLSIQNEKRANELEQSVDHMK 849
Query: 821 AQ-------LRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEE-----QEILECLKCEH 868
Q LR KR+QL ++ ++D + K+I K QEE E L+ +
Sbjct: 850 YQKIQLQRKLREENEKRKQLDAVI--KRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKR 907
Query: 869 DKES--------RLLEKH---DESVTDVTEVPQDFEK----IKPVEYRLQYKERQLQYLL 913
K S +L E+ DE V V Q+ E+ +K E + KE LQ
Sbjct: 908 RKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQE-- 965
Query: 914 QNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATF 973
++HL +K R+ + L+ L + L +E+E+ EK QL +T
Sbjct: 966 KSHLE---NKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQ------------TSTA 1010
Query: 974 EFTANIARQEEKVRKKEKEILESREKQQREAL----------ERALARLERRHSALQRHS 1023
E I+ Q E V +KEK+ L+ R E L E L +LE AL+
Sbjct: 1011 EEKTKISEQVE-VLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAI 1069
Query: 1024 TLGMEIEEQRQK--LASLNSGSREQSGLQASLEAEQEA---------------LEKDQER 1066
E + RQK AS ++ SR ++ + L L + + +
Sbjct: 1070 EYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERK 1129
Query: 1067 LEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEE- 1125
+ +++K K+ E D + ++ L+ ++ ++ M ++ + E++
Sbjct: 1130 QQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDG 1189
Query: 1126 ---------VQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKL 1163
+ ++Q L + + TS D K ++L I+R+L
Sbjct: 1190 EGIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQL 1236
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 304 bits (778), Expect = 4e-82
Identities = 193/420 (45%), Positives = 246/420 (58%), Gaps = 38/420 (9%)
Query: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
+VKV VR RP+N REK + K + +++ + TIT K DS E KTFT+D +
Sbjct: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKT------DSSNEPPKTFTFD-TV 66
Query: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
+ ++K D V+ ++ S EGYN +FAYGQTG+GK++TM G
Sbjct: 67 FGPESKQLD------VYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR 120
Query: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
G+IP +F I + + F VSYLEIYNE VRDLL + +T L V+E P
Sbjct: 121 GIIPNSFAHIFGHIAKAE--GDTRFLVRVSYLEIYNEEVRDLLGK--DQTQRLEVKERPD 176
Query: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKF--TQAKFD 237
G Y++DLS ++V N D++ +M G+ NR+ AT MN+ SSRSHAIFTI ++ D
Sbjct: 177 VGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGID 236
Query: 238 SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAA 297
M + K+HLVDLAGSER TGATG RLKE IN SL TLGNVISAL D
Sbjct: 237 GNMHVR-MGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVD------ 289
Query: 298 NTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKN 357
K VPYR+S LT LL+DSLGGNSKT+M A I PAD NY ET+STLRYANRAKN
Sbjct: 290 -----GKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKN 344
Query: 358 IINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQE 417
I NK INED L+R+ + EI LK L +G +I S + +S E+ E V E
Sbjct: 345 IKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEI----SGSDISGSEEDDDEEGEVGE 400
Score = 59.7 bits (143), Expect = 2e-08
Identities = 62/255 (24%), Positives = 120/255 (47%), Gaps = 34/255 (13%)
Query: 550 RFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYN-------------PGL 596
R + K A++ E K LL F + +L K E + + G
Sbjct: 341 RAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGE 400
Query: 597 EFERQQREELEKLESKRKLIE---EMEEKQKS-----DKAELERMQQEVETQRKETEIVQ 648
+ E++++ +K S K+IE +++E++K+ D E ER + E +++E ++++
Sbjct: 401 DGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLK 460
Query: 649 LQIRKQEESLKRRSFHIENKL----KDLLAEKEKFEEERLREQQEIELQKKRQEEETFLR 704
Q ++ +SL + +E K+ DLLA+ E E+E+L E+ +EL+++R+ E R
Sbjct: 461 AQ--QEHQSLLEKLSALEKKVIVGGVDLLAKAE--EQEKLLEESNMELEERRKRAEQLRR 516
Query: 705 VQEELQRLKELNNNEKAEKFQIFQELDQLQKEK-DEQYAKLELEKKRLEEQEKEQVMLVA 763
EE KE + EK+ QE Q + +K + + L K + + ++E +
Sbjct: 517 ELEE----KEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIE 572
Query: 764 HLEEQLREKQEMIQL 778
L E +R+ ++L
Sbjct: 573 GLLENIRQLSRELRL 587
Score = 44.7 bits (104), Expect = 6e-04
Identities = 51/196 (26%), Positives = 91/196 (46%), Gaps = 27/196 (13%)
Query: 600 RQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLK 659
RQ ++E+E+L+ K + EE+ S E + + EV ++ + + + + + +
Sbjct: 361 RQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMI 420
Query: 660 RRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNE 719
I+ + K L + + EEER + + E+E + E+ L+ Q+E Q L L
Sbjct: 421 EMQAKIDEERKALETKLDMEEEERNKARAELE-----KREKDLLKAQQEHQSL--LEKLS 473
Query: 720 KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLL 779
EK I +D L AK E ++K LEE E L E+++ + L
Sbjct: 474 ALEKKVIVGGVDLL--------AKAEEQEKLLEESNME-----------LEERRKRAEQL 514
Query: 780 RRGEVQWVEEEKRDLE 795
RR E++ E+E+ D+E
Sbjct: 515 RR-ELEEKEQERLDIE 529
Score = 41.6 bits (96), Expect = 0.005
Identities = 72/339 (21%), Positives = 145/339 (42%), Gaps = 43/339 (12%)
Query: 707 EELQRLKELNNNEKAEKFQIFQ-ELDQLQK--EKDEQYAKLELEKKRLEEQEKEQVMLVA 763
+ ++ +N + K + FQ E+++L+K E+ E+ + ++ ++ E+ +V
Sbjct: 343 KNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDG 402
Query: 764 HLEEQLREKQE-----MIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEEL 818
++ R K++ MI++ + ++EE++ LE L +E R + E+
Sbjct: 403 EKRKKRRGKKKVSPDKMIEMQAK-----IDEERKALE---TKLDMEEEERNKARAELEKR 454
Query: 819 EKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCE----------- 867
EK L+ + + L KL LEK ++ L + +E++++LE E
Sbjct: 455 EKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQL 514
Query: 868 ----HDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNH---LPTL 920
+KE L+ ++ + E +K+K V L + ++ L Q H + L
Sbjct: 515 RRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGL 574
Query: 921 LEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIA 980
LE ++ L L +DN + ++ +E E + + + Q L+ N+
Sbjct: 575 LENIRQLSRELRLQMLIIDNF---IPRDYQEMIENYVHWNEDIGEWQ-LKCVAYTGNNMR 630
Query: 981 RQEEKVRKKEKEILESREKQ-----QREALERALARLER 1014
+Q KKEK+ E E+L ++L +LER
Sbjct: 631 KQTPVPDKKEKDPFEVDLSHVYLAYTEESLRQSLMKLER 669
Score = 36.2 bits (82), Expect = 0.21
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 28/178 (15%)
Query: 944 QVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIAR----QEEKVRKKEKEILESREK 999
+V ++ E+++++ + + + +++ ++QA + EE+ R K + LE REK
Sbjct: 397 EVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREK 456
Query: 1000 QQREALERALARLERRHSALQRHSTLG-------------------MEIEEQRQKLASLN 1040
+A + + LE+ SAL++ +G ME+EE+R++ L
Sbjct: 457 DLLKAQQEHQSLLEKL-SALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLR 515
Query: 1041 SGSREQSGLQASLEAEQEALEKDQE----RLEYEIQQLKQKIYEVDGVQKDHHGTLEG 1094
E+ + +E + +L+++ + +L+ L E+ +Q++H +EG
Sbjct: 516 RELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEG 573
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 295 bits (754), Expect = 3e-79
Identities = 188/417 (45%), Positives = 244/417 (58%), Gaps = 40/417 (9%)
Query: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
+VKV VR RPMN+RE++L + ++ ++ ++ I G D E K FT+D ++
Sbjct: 5 AVKVVVRCRPMNQRERELRCQPVVTVDCARAQCC---IQNPGAAD---EPPKQFTFDGAY 58
Query: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMG---NSGDS 119
+ D+V+ E ++ + +V+ EGYN +FAYGQTGSGKS+TM G
Sbjct: 59 HV------DHVT-EQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQR 111
Query: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
G+IPR E +F + + F SYLEIYNE VRDLL + + L ++EHP+
Sbjct: 112 GIIPRAFEHVFESVQCA---ENTKFLVRASYLEIYNEDVRDLLGADTKQ--KLELKEHPE 166
Query: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSE 239
+G YV+ LS H V + E +M+ G NR+ T MN SSRSH+IFTI + D
Sbjct: 167 KGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDER 226
Query: 240 MPCET-VSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAAN 298
K++LVDLAGSER TGATG RLKE IN SL LGNVISAL D
Sbjct: 227 GKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVD------- 279
Query: 299 TLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNI 358
+ VPYRDS LT LL+DSLGGN+KT+M+A +SPAD NY ETLSTLRYANRAKNI
Sbjct: 280 ----GRCKHVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNI 335
Query: 359 INKPTINEDANVKLIRELRAEIARLKTLLAQ----GNQIALLD---SPTALSMEEKL 408
NKP INED L+RE + EI +LK +L Q + ALL P + +EEKL
Sbjct: 336 RNKPRINEDPKDALLREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKL 392
Score = 31.6 bits (70), Expect = 5.2
Identities = 21/80 (26%), Positives = 45/80 (56%), Gaps = 13/80 (16%)
Query: 607 EKLESKRKLIEEMEEKQKSDKAELERMQQE-----------VETQRKETEIVQLQIRKQE 655
E++ +K KL+E+M+ K ++ + E++ +Q E + Q +++ ++Q Q+ +Q
Sbjct: 806 EEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLLQ-QLLEQV 864
Query: 656 ESLKRRSFHIENKLKDLLAE 675
+ L RR + N L+ +L E
Sbjct: 865 QPLIRRDCNYSN-LEKILRE 883
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 295 bits (754), Expect = 3e-79
Identities = 188/417 (45%), Positives = 244/417 (58%), Gaps = 40/417 (9%)
Query: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
+VKV VR RPMN+RE++L + ++ ++ ++ I G D E K FT+D ++
Sbjct: 5 AVKVVVRCRPMNQRERELRCQPVVTVDCARAQCC---IQNPGAAD---EPPKQFTFDGAY 58
Query: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMG---NSGDS 119
+ D+V+ E ++ + +V+ EGYN +FAYGQTGSGKS+TM G
Sbjct: 59 HV------DHVT-EQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQR 111
Query: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
G+IPR E +F + + F SYLEIYNE VRDLL + + L ++EHP+
Sbjct: 112 GIIPRAFEHVFESVQCA---ENTKFLVRASYLEIYNEDVRDLLGADTKQ--KLELKEHPE 166
Query: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSE 239
+G YV+ LS H V + E +M+ G NR+ T MN SSRSH+IFTI + D
Sbjct: 167 KGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDER 226
Query: 240 MPCET-VSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAAN 298
K++LVDLAGSER TGATG RLKE IN SL LGNVISAL D
Sbjct: 227 GKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVD------- 279
Query: 299 TLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNI 358
+ VPYRDS LT LL+DSLGGN+KT+M+A +SPAD NY ETLSTLRYANRAKNI
Sbjct: 280 ----GRCKHVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNI 335
Query: 359 INKPTINEDANVKLIRELRAEIARLKTLLAQ----GNQIALLD---SPTALSMEEKL 408
NKP INED L+RE + EI +LK +L Q + ALL P + +EEKL
Sbjct: 336 RNKPRINEDPKDALLREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKL 392
Score = 31.6 bits (70), Expect = 5.2
Identities = 21/80 (26%), Positives = 45/80 (56%), Gaps = 13/80 (16%)
Query: 607 EKLESKRKLIEEMEEKQKSDKAELERMQQE-----------VETQRKETEIVQLQIRKQE 655
E++ +K KL+E+M+ K ++ + E++ +Q E + Q +++ ++Q Q+ +Q
Sbjct: 806 EEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLLQ-QLLEQV 864
Query: 656 ESLKRRSFHIENKLKDLLAE 675
+ L RR + N L+ +L E
Sbjct: 865 QPLIRRDCNYSN-LEKILRE 883
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 292 bits (747), Expect = 2e-78
Identities = 340/1262 (26%), Positives = 568/1262 (45%), Gaps = 146/1262 (11%)
Query: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
+V V VRVRP+N RE+ L + + I + + +K+F +D F
Sbjct: 6 AVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQV------------DGSKSFNFDRVF 53
Query: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLI 122
+ +T + V++ + ++ SA +GYN +FAYGQT SGK+YTMMG+ G+I
Sbjct: 54 HGNETT-------KNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVI 106
Query: 123 PRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGP 182
PR +F +I ++ + F VSY+EIYNE + DLL + K L +RE
Sbjct: 107 PRAIHDIFQKIK---KFPDREFLLRVSYMEIYNETITDLL-CGTQKMKPLIIREDVNRNV 162
Query: 183 YVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPC 242
YV DL++ +V + + G +R T MN SSRSH IF + + C
Sbjct: 163 YVADLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNC 222
Query: 243 E---TVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANT 299
E VS ++LVDLAGSERA TGA GVRLKEG NIN+SL LG VI L+D
Sbjct: 223 EGSVKVSHLNLVDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGG--- 279
Query: 300 LAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNII 359
F+ YRDS LT +L++SLGGN+KT +I TI+P V++ ETL+ L++A+ AK +
Sbjct: 280 -------FINYRDSKLTRILQNSLGGNAKTRIICTITP--VSFDETLTALQFASTAKYMK 330
Query: 360 NKPTINE-DANVKLIRELRAEIARLKTLL----AQGNQIALLDSPTALSMEEK--LQ--Q 410
N P +NE + L++ R EI LK L + A+ A +EEK LQ Q
Sbjct: 331 NTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQ 390
Query: 411 NEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLD--SELPHLIGIDDDLLSTGI 468
NE +++ LT+ + T L+++ A RK + L +++ + D + T I
Sbjct: 391 NE-KIENLTRMLVTSSSLT---LQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNI 446
Query: 469 ILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQ 528
K + D S + SE +F N T++ I + + +N
Sbjct: 447 TTKTHKLSINLLREIDES-----------VCSESDVFSNTLDTLSEIEWNPATKLLNQEN 495
Query: 529 I-VEATHLNQGAVILLGRTNMFRFNHPKEAAKLREK----------RKSGLLSSFSLSMT 577
I E L L+ R + KL+EK RK+ L +
Sbjct: 496 IESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQL-IH 554
Query: 578 DLSKSRENLSAVMLYNPGLEFERQQREEL--EKLESKRKLIEEME-EKQKSDKAELERMQ 634
++S + + +YN LE E + EL EK + +KL E ++ +K ++ K +L
Sbjct: 555 EISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSL 614
Query: 635 QEVE--TQRKET----EIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQ 688
+ +E Q K+T E V L +++ L+ + ++ K+K+L ++ E + Q
Sbjct: 615 ESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQS 674
Query: 689 EIELQKKRQE--EETFLRVQEELQRLKELNNNEKAEKFQIFQELD----QLQKEKDEQYA 742
++E +KK Q E+ E+ +L L + + + EL+ LQKE +++
Sbjct: 675 QLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVE 734
Query: 743 KLEL--EKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEE---EKRDLEGI 797
+ E E+ L + K V L +++++K E + ++ + + E ++ ++G+
Sbjct: 735 ENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGL 794
Query: 798 RESLLRVKE--ARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDI-LKKEV 854
E + + K+ A + + E + Q K+V E + + Q+ + L KE
Sbjct: 795 LEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEA 854
Query: 855 QEEQEILECLKCEHD-KESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQ----- 908
Q+ L LK E K L EK E + E+ Q E+++ + LQ ER+
Sbjct: 855 QKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLIT 914
Query: 909 --LQYLLQNHLPTLLEEKQRAFEI-----LDRGPLSLD-----NTLYQVEKEMEEKEEQL 956
LQ L+ + TL +EK ++ ++R L D N ++++ E L
Sbjct: 915 EKLQQTLE-EVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESL 973
Query: 957 AQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRH 1016
Q+Q N L K + + E + N+ +E K+ E QQ+ LE ++
Sbjct: 974 KQHQETINTL-KSKISEEVSRNLHMEENTGETKD-------EFQQKMVGIDKKQDLEAKN 1025
Query: 1017 SALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKD-QERLEYEIQQLK 1075
+ EI EQ++K+ SL E + S+ AE+E L+ D +E +E I+ +
Sbjct: 1026 TQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQE 1085
Query: 1076 QKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHR 1135
+ D ++K + K + ++ E S + A +EE+++ + Q L
Sbjct: 1086 ELRLLGDELKKQQEIVAQEK--NHAIKKEGELSRTCDRL-----AEVEEKLKEKSQQLQE 1138
Query: 1136 V------ISEGCSTSADTMKDNEKLHNGTIQRKLKYERM------VSRSLGANPDDLKDP 1183
+ E S + + E L N ++L E M +++ L N +++K
Sbjct: 1139 KQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSI 1198
Query: 1184 IK 1185
K
Sbjct: 1199 TK 1200
Score = 112 bits (279), Expect = 3e-24
Identities = 191/877 (21%), Positives = 388/877 (44%), Gaps = 159/877 (18%)
Query: 379 EIARLKTLLAQGNQIALLDSPTA-LSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQT 437
EI LK L + ++ L T L + +KL +N V+ +TKE + +LKE
Sbjct: 1159 EIENLKNEL-KNKELTLEHMETERLELAQKLNENYEEVKSITKE--------RKVLKE-- 1207
Query: 438 LALRKEGIGVVLDSELPHLIGIDDDLLSTG--------IILYHLKEGQTYVG--RDDAST 487
L+K ++E HL G ++ +TG I HLKE Q + R S
Sbjct: 1208 --LQKS-----FETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSE 1260
Query: 488 EQDIVLHGLDLESEHCIFEN----IGGTVTLIP----LSGSQCSVNGVQIVEATHLNQGA 539
+ +++ DLE H + + L+P +S +Q ++N ++++ + +
Sbjct: 1261 KTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDS 1320
Query: 540 VILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFE 599
L R M R ++ + +E+ KS L+K R+NL + LE +
Sbjct: 1321 T-TLARIEMERLRLNEKFQESQEEIKS------------LTKERDNLKTI---KEALEVK 1364
Query: 600 RQQ-----REELEKLESKR-----------------KLIEEMEEKQKSDKA--------- 628
Q RE L K++ + K++ EME+ + D A
Sbjct: 1365 HDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEML 1424
Query: 629 ELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEER----- 683
L + QE + K + +++ +E L+ S ++ +K+++A+ + EEE
Sbjct: 1425 GLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHC 1484
Query: 684 -LREQQEI--ELQKKRQEEETFL-RVQEELQRLKELNNN------EKAEKFQIFQELDQL 733
L+EQ+E EL+ E+ET + +Q++L+ + + N EK E+F I Q +
Sbjct: 1485 CLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQ 1544
Query: 734 QKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRD 793
+K + + K + K Q E ML L +L+E QE IQ++ + EK +
Sbjct: 1545 EKVNELKQFKEHRKAKDSALQSIESKML--ELTNRLQESQEEIQIMIK--------EKEE 1594
Query: 794 LEGIRESL-LRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKK 852
++ ++E+L + + + E +++++Q + ++F + + VN ++ + + + LK+
Sbjct: 1595 MKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLK---MTAVNETQEKMCEIEHLKE 1651
Query: 853 EVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYL 912
+ + ++ LE ++ E+ + +++L ++ E + VT+ D ++ VE L+ + QL+
Sbjct: 1652 QFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDD---LRSVEETLKVERDQLKEN 1708
Query: 913 LQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQAT 972
L+ + L EKQ +I+ T+ ++ + EK N++ +Q
Sbjct: 1709 LRETITRDL-EKQEELKIVHMHLKEHQETIDKLRGIVSEK----------TNEISNMQKD 1757
Query: 973 FEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQ 1032
E + + + ++ ++E I K+Q+E +++ + + L S + ++E
Sbjct: 1758 LEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKL---SNMQKDLE-- 1812
Query: 1033 RQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTL 1092
NS ++ Q +Q E +A E L+ ++ + ++K+ E++ ++K
Sbjct: 1813 -------NSNAKLQEKIQ-----ELKANEHQLITLKKDVNETQKKVSEMEQLKK------ 1854
Query: 1093 EGKVASSSLPVSAEKSHLVPLMDARINAYIEE--EVQRRLQDLHRVISEGCSTSADTMKD 1150
++ SL +S + + L +++ +EE V + +L RV E D +K+
Sbjct: 1855 --QIKDQSLTLSKLEIENLNLAQ-KLHENLEEMKSVMKERDNLRRV-EETLKLERDQLKE 1910
Query: 1151 N---EKLHNGTIQRKLKYERMVSRSLGANPDDLKDPI 1184
+ K + IQ++LK RM+S+ D L++ I
Sbjct: 1911 SLQETKARDLEIQQELKTARMLSKEHKETVDKLREKI 1947
Score = 90.1 bits (222), Expect = 1e-17
Identities = 105/516 (20%), Positives = 235/516 (45%), Gaps = 62/516 (12%)
Query: 604 EELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQ----RKETEIVQLQIRKQEESLK 659
EE+ + +R + +EE K ++ +L+ +E T+ ++E +IV + +++ +E++
Sbjct: 1679 EEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETID 1738
Query: 660 R-------RSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRL 712
+ ++ I N KDL + + + L+ Q+E+ + +E+ QE + +L
Sbjct: 1739 KLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQ-----QETIDKL 1793
Query: 713 KELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREK 772
+ + + EK +K L +QK+ + AKL+ + + L+ E + + L + E ++
Sbjct: 1794 RGIVS-EKTDK------LSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKV 1846
Query: 773 QEMIQLLRRGEVQWVEEEKRDLEGIR--ESLLRVKEARAGGDEDGEELEKAQLRFFEFKR 830
EM QL ++ + Q + K ++E + + L E ++ + L + + + +R
Sbjct: 1847 SEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVE-ETLKLER 1905
Query: 831 RQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEH-DKESRLLEKHDESVTDVTEVP 889
QL K+ +Q+ E+Q+E + L EH + +L EK E ++++
Sbjct: 1906 DQL-------KESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQ 1958
Query: 890 QDFEKIKPVEYR----LQYKERQLQYL-----LQNHLPTLLEEKQRAFEILDRGPLSLDN 940
+D +K K + LQ KE QL + + + +E+ ++ FE + S+
Sbjct: 1959 KDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRM 2018
Query: 941 TLYQVEKEMEEKEEQLAQYQANANQLQKLQATF-----EFTANIA------RQEEKVRKK 989
+Q+ K++ E E++ ++L++++ + +F A + RQ +V K
Sbjct: 2019 DNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQV-KP 2077
Query: 990 EKEILESREKQQREALERALARLE---RRHSALQRH----STLGMEIEEQRQKLASLNSG 1042
EK +L ++ E+L +R++ +R+S + H + L +++E++ + L+
Sbjct: 2078 EKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMR 2137
Query: 1043 SREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKI 1078
+ L E L +R E ++ +K+
Sbjct: 2138 VKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKL 2173
Score = 89.4 bits (220), Expect = 2e-17
Identities = 196/891 (21%), Positives = 370/891 (41%), Gaps = 123/891 (13%)
Query: 347 STLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEE 406
STL+ R K +I + VK + + + ++ +L+ L D ++M
Sbjct: 901 STLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNI 960
Query: 407 KLQQNEARVQELTKEWTNKWNETQNILKEQTLAL--RKEGIGVVLDSELPHLIGID--DD 462
Q+ E K+ N ++ + E+ +E G D ++GID D
Sbjct: 961 DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQD 1020
Query: 463 LLSTGIILYHLKEGQTYVG--RDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGS 520
L K QT +D+ EQ + L E + + +
Sbjct: 1021 L--------EAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNE-----LQQMLESVIAEKE 1067
Query: 521 QCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLS 580
Q + + +E T NQ + LLG + K+ ++ + K+ + +LS
Sbjct: 1068 QLKTDLKENIEMTIENQEELRLLG-------DELKKQQEIVAQEKNHAIKKEG----ELS 1116
Query: 581 KSRENLSAVMLYNPGLEFERQQREELEKLESKRKLI----EEMEEKQKSDKAELERMQQE 636
++ + L+ E E + +E+ ++L+ K++ + EEM E QK E+E ++ E
Sbjct: 1117 RTCDRLA---------EVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKIN-EIENLKNE 1166
Query: 637 VET-----QRKETEIVQLQIRKQEESLKRRSFHIENK-LKDLLAEKEKFEEER------L 684
++ + ETE ++L + E + +S E K LK+L ++ FE ER +
Sbjct: 1167 LKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKEL---QKSFETERDHLRGYI 1223
Query: 685 REQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIF--QELDQLQKEKDEQYA 742
RE + LQ K + + + ++E + + EL + + QI Q+L++ + E+
Sbjct: 1224 REIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIP 1283
Query: 743 KLELEKKRL----EEQEKEQVMLVAHL-EEQLREKQ-------EMIQLLRRGEVQWVEEE 790
L E++ L E E ++ M L EQ K EM +L + Q +EE
Sbjct: 1284 VLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEE 1343
Query: 791 KRDLEGIRESLLRVKEA-RAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDI 849
+ L R++L +KEA D+ E + + + E + +Q L EKD K +
Sbjct: 1344 IKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIV 1403
Query: 850 LKKEVQEEQEILECLKCEHDK---ESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKE 906
+ E Q + + L+ E + RL E HDE + V + D ++++ V LQ +
Sbjct: 1404 SEME-QFKPKDSALLRIEIEMLGLSKRLQESHDE-MKSVAKEKDDLQRLQEV---LQSES 1458
Query: 907 RQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQL 966
QL+ ++ + LE ++ ++ + T+ ++ + EKE +++ Q +
Sbjct: 1459 DQLKENIKEIVAKHLETEEE-LKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAI 1517
Query: 967 Q-KLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTL 1025
KLQ + I +EE+ K+ ++ + + ++ E A+ SALQ +
Sbjct: 1518 NDKLQNKIQ---EIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAK----DSALQSIESK 1570
Query: 1026 GMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQ 1085
+E+ + Q+ Q +Q ++ E+E +++ QE L+ E QLK+ E+
Sbjct: 1571 MLELTNRLQE---------SQEEIQIMIK-EKEEMKRVQEALQIERDQLKENTKEIVAKM 1620
Query: 1086 KD----HHGTLEGKVASSSLPVSAEKSHLVPLMDA-RIN-AYIEEEVQRRLQDLHRVISE 1139
K+ + L+ + + E HL + ++N IE E R Q LH + E
Sbjct: 1621 KESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEE 1680
Query: 1140 GCSTSADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPR 1190
S + K+ + L +++ LK ER D LK+ ++ +I R
Sbjct: 1681 MRSVT----KERDDLR--SVEETLKVER----------DQLKENLRETITR 1715
Score = 80.9 bits (198), Expect = 8e-15
Identities = 136/638 (21%), Positives = 260/638 (40%), Gaps = 86/638 (13%)
Query: 561 REKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEME 620
+E R GLL + DL+ ++ N + ++ ++ + L + E
Sbjct: 787 KESRVQGLLEEIGKTKDDLATTQSNYKSTD----------------QEFQNFKTLHMDFE 830
Query: 621 EKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFE 680
+K K E ERM QE+ KE + K + SL + K ++L EK +
Sbjct: 831 QKYKMVLEENERMNQEIVNLSKEAQ-------KFDSSLGALKTELSYKTQEL-QEKTREV 882
Query: 681 EERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQ 740
+ERL E ++++ Q + ++ T V+ E + E E + QE D L++ ++
Sbjct: 883 QERLNEMEQLKEQLENRDS-TLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQES- 940
Query: 741 YAKLELEKKRLEEQEKEQVMLVAHLEEQLR-------EKQEMIQLLRRGEVQWVEEEKRD 793
L++E+ +L+ + V + +EQLR + QE I L+ + V
Sbjct: 941 ---LQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHM 997
Query: 794 LEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKE 853
E E+ ++ G D+ + E K Q + + ++++Q+ +
Sbjct: 998 EENTGETKDEFQQKMVGIDKKQD---------LEAKNTQTLTADVKDNEIIEQQRKIFSL 1048
Query: 854 VQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKE--RQLQY 911
+QE+ E+ + L ES + EK ++ TD+ E +E ++ +E R L
Sbjct: 1049 IQEKNELQQML------ESVIAEK-EQLKTDLKE---------NIEMTIENQEELRLLGD 1092
Query: 912 LLQNHLPTLLEEKQRAFEILDRGPLSLD-NTLYQVEKEMEEKEEQLAQYQANANQLQKLQ 970
L+ + +EK A I G LS + L +VE++++EK +QL + Q +Q+
Sbjct: 1093 ELKKQQEIVAQEKNHA--IKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEM 1150
Query: 971 ATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHST---LGM 1027
+ + N + K ++ LE E ++ E ++ E S + L
Sbjct: 1151 SEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQK 1210
Query: 1028 EIEEQRQKLASLNSGSREQSGLQA--SLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQ 1085
E +R L E +GLQ L+ L++ QE ++ + + +K ++ Q
Sbjct: 1211 SFETERDHLRGY-IREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQ 1269
Query: 1086 --KDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCST 1143
+ H L+ +PV E+ L+P N E Q + +L +++E +T
Sbjct: 1270 DLEKSHTKLQ-----EEIPVLHEEQELLP------NVKEVSETQETMNEL-ELLTEQSTT 1317
Query: 1144 SADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLK 1181
T ++ + K + + +SL D+LK
Sbjct: 1318 KDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLK 1355
Score = 75.9 bits (185), Expect = 2e-13
Identities = 174/812 (21%), Positives = 335/812 (41%), Gaps = 142/812 (17%)
Query: 362 PTINEDA----NVKLIRELRAEIARLKTLLAQGNQIALLDSPTA-------LSMEEKLQQ 410
P ++E+ NVK + E + + L+ L Q DS T L + EK Q+
Sbjct: 1283 PVLHEEQELLPNVKEVSETQETMNELELLTEQSTT---KDSTTLARIEMERLRLNEKFQE 1339
Query: 411 NEARVQELTKEWTN--KWNETQNILKEQTLALRKEGIGVVLDSELPHLIGI---DDDLLS 465
++ ++ LTKE N E + +Q +E + + +S+ + + D +
Sbjct: 1340 SQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNET 1399
Query: 466 TGIILYHLKEGQTYVGRDDASTEQDIVLHGLD--LESEHCIFENIGGTVT-------LIP 516
T I+ E + + +D A +I + GL L+ H +++ ++
Sbjct: 1400 TKIV----SEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQ 1455
Query: 517 LSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSM 576
Q N +IV A HL + + + K +E+ + L + S
Sbjct: 1456 SESDQLKENIKEIV-AKHLETEEELKVAHCCL----------KEQEETINELRVNLSEKE 1504
Query: 577 TDLSKSRENLSAV--MLYNPGLE-FERQQREELEKLESKRKLIEEMEEKQKSDKAE---- 629
T++S ++ L A+ L N E +E++++ ++++ ++ + E+++ ++ KA+
Sbjct: 1505 TEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSAL 1564
Query: 630 -------------LERMQQEVETQRKETEI---VQLQIRKQEESLKRRSFHIENKLKDLL 673
L+ Q+E++ KE E VQ ++ + + LK + I K+K+
Sbjct: 1565 QSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQ 1624
Query: 674 AEKEKF--------------EEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNE 719
++ +F E E L+EQ E QK E ++ E RL ++ +
Sbjct: 1625 EKEYQFLKMTAVNETQEKMCEIEHLKEQ--FETQKLNLE-----NIETENIRLTQILHEN 1677
Query: 720 KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQ-----EKEQVMLVAHLEEQLREKQE 774
E + +E D L+ ++ + + K+ L E EK++ + + H+ L+E QE
Sbjct: 1678 LEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHM--HLKEHQE 1735
Query: 775 MIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGD-EDGEELEKAQLRFFE-----F 828
I LR V E+ ++ +++ L +A D + EEL A + E
Sbjct: 1736 TIDKLR----GIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETID 1791
Query: 829 KRRQLV-----KLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVT 883
K R +V KL N++KDL L++++QE LK + L + +E+
Sbjct: 1792 KLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQE-------LKANEHQLITLKKDVNETQK 1844
Query: 884 DVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLY 943
V+E+ Q ++IK L E + L Q L LEE + + D L
Sbjct: 1845 KVSEMEQLKKQIKDQSLTLSKLEIENLNLAQK-LHENLEEMKSVMKERD--------NLR 1895
Query: 944 QVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQRE 1003
+VE+ ++ + +QL + LQ T I ++ + R KE E+ +K + +
Sbjct: 1896 RVEETLKLERDQLK---------ESLQETKARDLEIQQELKTARMLSKEHKETVDKLREK 1946
Query: 1004 ALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKD 1063
E+ + + + + L +I+E ++K L R + + S ++ E +
Sbjct: 1947 ISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQL---LRVKEDVNMS---HKKINEME 2000
Query: 1064 QERLEYEIQQLKQKIYEVDGVQ--KDHHGTLE 1093
Q + ++E Q L + +D Q K H +LE
Sbjct: 2001 QLKKQFEAQNLSMQSVRMDNFQLTKKLHESLE 2032
Score = 75.9 bits (185), Expect = 2e-13
Identities = 162/745 (21%), Positives = 325/745 (43%), Gaps = 100/745 (13%)
Query: 392 QIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQN----------ILKEQTLALR 441
QI + + ++E LQ +++E TKE K E+Q + + Q
Sbjct: 1586 QIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCE 1645
Query: 442 KEGIGVVLDSELPHLIGID-DDLLSTGIILYHLKEGQTYVG-RDDASTEQDIVLHGLDLE 499
E + +++ +L I+ +++ T I+ +L+E ++ RDD + ++ L +E
Sbjct: 1646 IEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEET----LKVE 1701
Query: 500 SEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATH-LNQGAVILLGRTNMFR-----FNH 553
+ + EN+ T+T + + + + E +++ I+ +TN H
Sbjct: 1702 RDQ-LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEH 1760
Query: 554 PKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQR-EELEK-LES 611
+A K ++ + + ++ L + +E + + G+ E+ + ++K LE+
Sbjct: 1761 SNDALKAQDLK---IQEELRIAHMHLKEQQETIDKLR----GIVSEKTDKLSNMQKDLEN 1813
Query: 612 KRKLIEEMEEKQKSDKAELERMQQEV-ETQRKETEIVQLQIRKQEESLKRRSFHIENKLK 670
++E ++ K+++ +L ++++V ETQ+K +E+ QL+ + +++SL IEN
Sbjct: 1814 SNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENL-- 1871
Query: 671 DLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQ----RLKELNNNEKAEKFQI 726
LA+K L E E E++ +E + RV+E L+ +LKE KA +I
Sbjct: 1872 -NLAQK-------LHENLE-EMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI 1922
Query: 727 FQELD---QLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGE 783
QEL L KE E KL ++++ E+ + + L++ E Q+ IQ L++ E
Sbjct: 1923 QQELKTARMLSKEHKETVDKL---REKISEKTIQISDIQKDLDKSKDELQKKIQELQKKE 1979
Query: 784 VQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRF------FEFKRRQLVKLV 837
+Q LLRVKE + E+E+ + +F + R +L
Sbjct: 1980 LQ---------------LLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLT 2024
Query: 838 NLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKP 897
+ +++ I+ KE E + I E LK E D+ L ++ + ++KP
Sbjct: 2025 KKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLR-------EMIARDRQNHQVKP 2077
Query: 898 VEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDR----GPLSLDNTLYQVEKEMEEKE 953
+ L ++ L L+ + E +R E+ D LSLD +EKE+E ++
Sbjct: 2078 EKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLD-----LEKEIEFQK 2132
Query: 954 EQLAQYQANAN----QLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERAL 1009
E + +AN + Q + ++ F + + ++ KK K +L K + E E ++
Sbjct: 2133 ELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHE-SI 2191
Query: 1010 ARLERRH-SALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLE 1068
+ E +++ L ++I+ +Q + SRE L+ + + E ++ E
Sbjct: 2192 NKFEMDFIDEVEKQKELLIKIQHLQQ---DCDVPSRELRDLKLNQNMDLHIEEILKDFSE 2248
Query: 1069 YEIQQLKQKIYEVDGVQKDHHGTLE 1093
E +K + +V +K+ LE
Sbjct: 2249 SEFPSIKTEFQQVLSNRKEMTQFLE 2273
Score = 66.2 bits (160), Expect = 2e-10
Identities = 174/816 (21%), Positives = 325/816 (39%), Gaps = 166/816 (20%)
Query: 568 LLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDK 627
LL + + DL K E +S LE Q E+ + +L+EE + QK
Sbjct: 344 LLKRYRKEIMDLKKQLEEVS--------LETRAQAMEK----DQLAQLLEEKDLLQKVQN 391
Query: 628 AELERM------------QQEVETQRKETEIVQL-QIRKQEESLKRRSFHIENKLKDLLA 674
++E + QQE++ +RK L +I K + S F+I ++
Sbjct: 392 EKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPT---NITT 448
Query: 675 EKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRL------KELN--------NNEK 720
+ K LRE E E + F + L + K LN N+ +
Sbjct: 449 KTHKLSINLLREIDESVCS----ESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLR 504
Query: 721 AEKFQIFQELDQLQKEKDEQYAKLE----------LEKKRLEEQEKEQV-------MLVA 763
A+ + + +QL+ EK+E KL+ LE+K ++QE + + LV
Sbjct: 505 ADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVK 564
Query: 764 HLE--------------EQLREKQEMIQLLRRG-EVQWVEEEKRDLEGIRESLLRVKEAR 808
H E E LREK++ I+ L+ + Q +E K DL ES+ K+ +
Sbjct: 565 HAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMK 624
Query: 809 AGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILEC-LKCE 867
D E + R F R + ++L K+L ++ ++Q Q LE K +
Sbjct: 625 Q-TLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQ 683
Query: 868 HDKESRLLEKHDESVTDVT-----EVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLE 922
D E L +E +T +T +VP+D +E ++ +++L ++ +
Sbjct: 684 VDLEKELQSAFNE-ITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEEN------ 736
Query: 923 EKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQ 982
E R IL SL + + ++ KE+++K E+L + ++L + + +
Sbjct: 737 EALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKL---------FSEVVHK 787
Query: 983 EEKVRKKEKEILESRE-----KQQREALERALARLERRHSAL-QRHSTLGMEIEEQRQKL 1036
E +V+ +EI ++++ + ++ ++ + H Q++ + E E Q++
Sbjct: 788 ESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEI 847
Query: 1037 ASLNSGSREQSGLQASLEAE--------QEALEKDQERLEYEIQQLKQKIYEVDGVQK-- 1086
+L+ +++ +L+ E QE + QERL E++QLK+++ D +
Sbjct: 848 VNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLN-EMEQLKEQLENRDSTLQTV 906
Query: 1087 DHHGTLEGKVASSSL----PVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCS 1142
+ TL + +L ++ EK L L ++ ++ E + D+H ++
Sbjct: 907 EREKTLITEKLQQTLEEVKTLTQEKDDLKQLQES-----LQIERDQLKSDIHDTVNMNID 961
Query: 1143 TSADTMKDNEKL--HNGTIQR-KLKYERMVSRSL--GANPDDLKDPIKISIPRYVLCGQG 1197
T E L H TI K K VSR+L N + KD + + G
Sbjct: 962 TQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKM-------VG 1014
Query: 1198 KDAHFEFEVKIT-----------VLDETWTVFRRYSRFREMHKTLKLKYAELAALEFPPK 1246
D + E K T ++++ +F E+ + L+ AE L+ K
Sbjct: 1015 IDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLK 1074
Query: 1247 -------------KLFGN---KDERVIAERRSHLEK 1266
+L G+ K + ++A+ ++H K
Sbjct: 1075 ENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIK 1110
Score = 42.0 bits (97), Expect = 0.004
Identities = 91/461 (19%), Positives = 183/461 (39%), Gaps = 74/461 (16%)
Query: 597 EFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEE 656
+ + +Q E + K E I+E+E KQK +++ +QQ+ + +E ++L
Sbjct: 2182 KIKEEQHESINKFEMD--FIDEVE-KQKELLIKIQHLQQDCDVPSRELRDLKLN------ 2232
Query: 657 SLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQE------------EETFLR 704
+ HIE LKD + +F + QQ + +K+ + E+
Sbjct: 2233 --QNMDLHIEEILKDF--SESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNG 2288
Query: 705 VQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAH 764
+Q+E R+ ++NN I E + ++ + E + K L+E+ ++
Sbjct: 2289 IQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQT 2348
Query: 765 LEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLR 824
L+ L ++ ++ K R + L ++ R ELE +
Sbjct: 2349 LKTSLASGAQVNPT--------TQDNKNPHVTSRATQLTTEKIR--------ELENSLHE 2392
Query: 825 FFEFKRRQLVKLVNLEKDLVQQKDILKK---EVQEEQEIL----ECLKCEHDKESRLLEK 877
E + K++ ++K+L DI+ K +V E + L E ++ DK + +
Sbjct: 2393 AKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKP 2452
Query: 878 HDESVTDVTE--VPQDFEKIKPV-EYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRG 934
+ E + D+ V D EK+K E+ + + Q + LL E R R
Sbjct: 2453 YKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLR------RS 2506
Query: 935 PLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEIL 994
+ D ++ + + + L + +Q +A + + E +R EKEI
Sbjct: 2507 QQAQDTSVISEHTDPQPSNKPLT-CGGGSGIVQNTKA-------LILKSEHIR-LEKEI- 2556
Query: 995 ESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQK 1035
S+ KQQ E L +++++ L + L E++ +++
Sbjct: 2557 -SKLKQQNEQL------IKQKNELLSNNQHLSNEVKTWKER 2590
Score = 34.3 bits (77), Expect = 0.81
Identities = 45/248 (18%), Positives = 102/248 (41%), Gaps = 29/248 (11%)
Query: 555 KEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRK 614
++ L+EK + + +L + S ++ N + NP + R + EK+
Sbjct: 2330 QDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVT-SRATQLTTEKIRELEN 2388
Query: 615 LIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIE-------- 666
+ E +E ++++ +MQ+E+E +Q ++ + + L++ I+
Sbjct: 2389 SLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVAL 2448
Query: 667 ------NKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRL--KELNNN 718
+++DL + K + E+++ +E E K+ + + Q+E+ RL + L +
Sbjct: 2449 GAKPYKEEIEDLKMKLVKIDLEKMKNAKEFE--KEISATKATVEYQKEVIRLLRENLRRS 2506
Query: 719 EKAEKFQIFQELDQLQKEKDE----------QYAKLELEKKRLEEQEKEQVMLVAHLEEQ 768
++A+ + E Q Q K + K EKE L E+
Sbjct: 2507 QQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQL 2566
Query: 769 LREKQEMI 776
+++K E++
Sbjct: 2567 IKQKNELL 2574
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 290 bits (741), Expect = 8e-78
Identities = 235/699 (33%), Positives = 347/699 (49%), Gaps = 110/699 (15%)
Query: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
SV+V VR RPMN +EK ++ ++ K ++K P+G + E KTFT+D +
Sbjct: 9 SVRVVVRCRPMNGKEKAASYDKVVDVDV-KLGQVSVKNPKG----TAHEMPKTFTFDAVY 63
Query: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
D + + + F+ L V S +G+N +FAYGQTG+GK+YTM G GD
Sbjct: 64 ---DWNAKQFELYDETFRPL----VDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKR 116
Query: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
G+IP + +F+ I+ R + SYLEIY E +RDLL + +K L ++E P
Sbjct: 117 GVIPNSFDHIFTHIS---RSQNQQYLVRASYLEIYQEEIRDLLSKDQTK--RLELKERPD 171
Query: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIF--TIKFTQAKFD 237
G YV+DLS + ++ ++E +M+ GN NR+ AT MN+ SSRSHAIF TI+ ++ D
Sbjct: 172 TGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLD 231
Query: 238 SEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAA 297
E V K++LVDLAGSER TGA G RLKE IN SL LGNVISAL D
Sbjct: 232 GENHIR-VGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVD------ 284
Query: 298 NTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKN 357
K +PYRDS LT LL+DSLGGN+KT+M+A + PA N ETL+TLRYANRAKN
Sbjct: 285 -----GKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKN 339
Query: 358 IINKPTINEDANVKLIRELRAEIARLKTLLAQGN-------QIALLDSPTALSMEEKLQQ 410
I NKP +NED L+RE + EIARLK L + + + + EE+ ++
Sbjct: 340 IKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEE 399
Query: 411 NEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIIL 470
E +E + + W E Q L+ + A+ ++D L +
Sbjct: 400 GEEGEEE-GDDKDDYWREQQEKLEIEKRAI------------------VEDHSLVAEEKM 440
Query: 471 YHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIV 530
LKE + + DL E E +G + + S+ V G IV
Sbjct: 441 RLLKEKEKKME---------------DLRREKDAAEMLGAKIKAME---SKLLVGGKNIV 482
Query: 531 EATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVM 590
+ H N+ IL + +E A+ + + + + S+ E L
Sbjct: 483 D--HTNEQQKILEQKR--------QEIAEQKRRER-------EIQQQMESRDEETLELKE 525
Query: 591 LYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQ 650
Y+ QQ ++ K K ++++ K ++ KAE+ +Q+E +R+E E Q +
Sbjct: 526 TYS-----SLQQEVDI-----KTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNE 575
Query: 651 IRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQE 689
+ ++ LK + IEN + L EK K +++E
Sbjct: 576 LTRE---LKLKHLIIENFIP--LEEKSKIMNRAFFDEEE 609
Score = 44.3 bits (103), Expect = 8e-04
Identities = 41/202 (20%), Positives = 94/202 (46%), Gaps = 20/202 (9%)
Query: 604 EELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSF 663
E+ + LE KR+ I E + +++ + ++E +E ++ +Q ++ + + LK+
Sbjct: 487 EQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKK--- 543
Query: 664 HIENKLKDLLAEKEKFEEERLREQQEI---------ELQKKRQEEETFLRVQEELQRLKE 714
+ +KL+ + AE +EE ++E+QE+ EL+ K E F+ ++E+ + +
Sbjct: 544 -LFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNR 602
Query: 715 LNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQE 774
+E+ + + +L + + +++Q K + + + + + + R + E
Sbjct: 603 AFFDEEEDHW----KLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAE 658
Query: 775 MIQLLRRGEVQWVEEEKRDLEG 796
I LL E+ RD EG
Sbjct: 659 NIVLL---ELDMPSRTTRDYEG 677
Score = 40.8 bits (94), Expect = 0.009
Identities = 37/173 (21%), Positives = 86/173 (49%), Gaps = 12/173 (6%)
Query: 600 RQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLK 659
+++ +++E L ++ E + K K+ +++L + + E + + Q R++ K
Sbjct: 444 KEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQK 503
Query: 660 RRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNE 719
RR I+ +++ E + +E QQE++++ K+ + ++ +LQ +K ++
Sbjct: 504 RREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLK-----KLFSKLQAVKAEIHDL 558
Query: 720 KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEE----QEKEQVMLVAHLEEQ 768
+ E + QEL+Q Q E + L+L+ +E +EK ++M A +E+
Sbjct: 559 QEEHIKERQELEQTQNELTRE---LKLKHLIIENFIPLEEKSKIMNRAFFDEE 608
Score = 36.6 bits (83), Expect = 0.16
Identities = 78/386 (20%), Positives = 158/386 (40%), Gaps = 51/386 (13%)
Query: 510 GTVTLIPLSGSQ----CSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRK 565
G + L+ L+GS+ G ++ EAT +N ++ LG + R+ +
Sbjct: 239 GKLNLVDLAGSERQAKTGAQGERLKEATKINL-SLSALGNVISALVDGKSTHIPYRDSKL 297
Query: 566 SGLLSSFSLSMTDLSKSRENLSAVMLYNPG-LEFERQQREELEKLESKRKLIEEMEEKQK 624
+ LL SL N VM+ N G + ++ + ++ K I+ +
Sbjct: 298 TRLLQD-SLG--------GNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNE 348
Query: 625 SDK-AELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEER 683
K A L Q+E+ + + E + RK+ E +R ++ E E+ EEE
Sbjct: 349 DPKDALLREFQEEIARLKAQLEKRSIGRRKRREK-RREGGGSGGGGEEEEEEGEEGEEEG 407
Query: 684 ------LREQQE-IELQKKRQEEETFLRVQEELQRLKE-----------------LNNNE 719
REQQE +E++K+ E+ L +E+++ LKE L
Sbjct: 408 DDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKI 467
Query: 720 KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKE----QVMLVAHLEEQLREKQEM 775
KA + ++ + +EQ LE +++ + EQ++ Q + + EE L K+
Sbjct: 468 KAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETY 527
Query: 776 IQLLRRGEVQWVEEEK--RDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQL 833
L + +++ + +K L+ ++ + ++E ++ E+ + R + K +
Sbjct: 528 SSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLII 587
Query: 834 VKLVNLEKDLVQQKDILKKEVQEEQE 859
+ LE ++ I+ + +E+E
Sbjct: 588 ENFIPLE----EKSKIMNRAFFDEEE 609
Score = 32.3 bits (72), Expect = 3.1
Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 7/162 (4%)
Query: 982 QEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHST----LGMEIEEQRQKLA 1037
Q+EK+ +++ I+E E + R L E++ L+R LG +I+ KL
Sbjct: 417 QQEKLEIEKRAIVEDHSLVAEEKM-RLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLL 475
Query: 1038 SLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVA 1097
+ + Q + ++ +Q+R E EIQQ + E K+ + +L+ +V
Sbjct: 476 VGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVD 535
Query: 1098 SSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISE 1139
+ + S L + A I+ EE ++ R Q+L + +E
Sbjct: 536 IKTKKLKKLFSKL-QAVKAEIHDLQEEHIKER-QELEQTQNE 575
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 285 bits (729), Expect = 2e-76
Identities = 319/1198 (26%), Positives = 527/1198 (43%), Gaps = 176/1198 (14%)
Query: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
++KV VR+RP R + + + + +T L KTFT+D
Sbjct: 26 AIKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLH---------SNPEPKTFTFD--- 73
Query: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
+ AD + +QE VF T+ +V+S GYN +FAYGQTGSGK++TMMG S
Sbjct: 74 HVADVDT----TQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFS 129
Query: 120 ----GLIPRICEGLFSRINETTRWDEA--SFRTEVSYLEIYNERVRDLLRRKSSKTFNLR 173
G+IPR E LFS I+ A SF + S++EIYNE++ DLL S + L
Sbjct: 130 HNLRGVIPRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLL---DSASAGLY 186
Query: 174 VREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQ 233
+REH K+G +V + +V + + +++ G NR A+T MN SSRSHA+FTI
Sbjct: 187 LREHIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIES 246
Query: 234 AKFDSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLS 293
+ +E+ S ++LVDLAGSER T A G+RLKE GNIN+SL LG VI+AL D+
Sbjct: 247 MEKSNEIVNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVG 306
Query: 294 QDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYAN 353
KQ V YRDS LT+LL+DSLGGN+KT +IA + P +GETLSTL +A
Sbjct: 307 NG--------KQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQ 358
Query: 354 RAKNIINKPTINED---------ANVKLIRELRAEIA-------------RLKTLLAQGN 391
RAK I NK +NED A VK ++E AE+A + KT +
Sbjct: 359 RAKLIKNKAVVNEDTQGNVSQLQAEVKRLKEQLAELASGQTPPESFLTRDKKKTNYMEYF 418
Query: 392 QIALLDSPTALSMEEKLQQNEARVQELT---------KEWTNKWNETQNILKEQTLALRK 442
Q A+L + ++ L + ++++LT + K+ E Q I E+ L K
Sbjct: 419 QEAMLFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMIVKFREDQIIRLEK---LHK 475
Query: 443 EGIGVVLDSELPHLIG-IDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESE 501
E G L E L+ + +++ + + H Y + + E++ L L+
Sbjct: 476 ESRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPVKR 535
Query: 502 HCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLR 561
+ T+ L + ++G+ E + NQ + F +
Sbjct: 536 AQEMD----AQTIAKLEKAFSEISGM---EKSDKNQQGFSPKAQKEPCLFANT------- 581
Query: 562 EKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELE-KLESKRK------ 614
EK K+ LL T+L+ S++ Y E R+++ ELE +L+S +K
Sbjct: 582 EKLKAQLLQI----QTELNNSKQE------YEEFKELTRKRQLELESELQSLQKANLNLE 631
Query: 615 -LIEEMEEKQKSDKAELERMQQE-VETQRKETEIVQLQIRKQEE-SLKRRSFHIENKLKD 671
L+E + ++ + ++L ++ E ++ T+ QL R + S + SF
Sbjct: 632 NLLEATKACKRQEVSQLNKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNS 691
Query: 672 LLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELD 731
+ + + E E E + +E T VQE++ L+ + E+ + ++ Q +D
Sbjct: 692 SILDNDILNEPVPPEMNEQAFEAISEELRT---VQEQMSALQAKLDEEEHKNLKLQQHVD 748
Query: 732 QLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEK 791
+L+ + E+ +Q++E + + LE+QL+E Q L+ E
Sbjct: 749 KLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLK--------SEV 800
Query: 792 RDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILK 851
DL + S +EL +L + FK Q + L + + + L
Sbjct: 801 HDLRVVLHSA-------------DKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLD 847
Query: 852 KEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQY 911
E +++LE C D L E + ++ Q+F+K + L+
Sbjct: 848 NLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKK----------ENETLKS 897
Query: 912 LLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEME----EKEEQLAQYQANANQLQ 967
L N + L EK+R ++ + +N+ ++ K +E EK+++ A+ + ++Q
Sbjct: 898 DLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQ 957
Query: 968 KLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLE-------------- 1013
KL+ + T + EK R +K+++ Q +E + E
Sbjct: 958 KLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINC 1017
Query: 1014 RRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQ--ERLEYEI 1071
+ +SAL + I++Q + L R L E +E+D E L +
Sbjct: 1018 KYNSALVDREESRVLIKKQEVDILDLKETLR--------LRILSEDIERDMLCEDLAHAT 1069
Query: 1072 QQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRR 1129
+QL + K H G L+ S+ +K L+ + ++N EE Q++
Sbjct: 1070 EQLNM----LTEASKKHSGLLQ-----SAQEELTKKEALIQELQHKLNQKKEEVEQKK 1118
Score = 73.6 bits (179), Expect = 1e-12
Identities = 109/583 (18%), Positives = 246/583 (42%), Gaps = 115/583 (19%)
Query: 596 LEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQI---- 651
+++ +QQ E L +L K ++E + K K+E+ ++ + + KE V+L+
Sbjct: 766 IDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFK 825
Query: 652 ---RKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQ------QEI------------ 690
K+ L R H++ +L +L E EK E + Q QEI
Sbjct: 826 TNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNL 885
Query: 691 ---------------------ELQKKRQ-------EEETFLRVQEELQRLKELNNNEKAE 722
E +K+R EE+ +E L+ L+ + ++ E
Sbjct: 886 QNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKE 945
Query: 723 KFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRG 782
+ Q++ ++QK +E E LE+ +VA L Q++E + +
Sbjct: 946 TAKCEQQMAKVQK-LEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSV----CE 1000
Query: 783 EVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKD 842
+ + ++ K++L+ I + A +E ++K ++ + K + ++L L +D
Sbjct: 1001 KTETIDTLKQELKDIN---CKYNSALVDREESRVLIKKQEVDILDLK--ETLRLRILSED 1055
Query: 843 LVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDF--------EK 894
+ ++D+L +++ E L L K S LL+ E +T + Q+ E+
Sbjct: 1056 I--ERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEE 1113
Query: 895 IKPVEYRLQYKERQLQYLL----------------QNHLPTLLEEKQRAFEILDRGPLSL 938
++ + +K RQL++++ Q HL LLE +++ E SL
Sbjct: 1114 VEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSL 1173
Query: 939 DNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTA-----------NIARQEE--- 984
++ + ++ ++ E K ++ + + +++ L+ + +I RQ+E
Sbjct: 1174 EHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSD 1233
Query: 985 -------KVRKKEKEILESREKQQR--EALERALARLERRHSALQRHSTLGMEIEEQRQK 1035
+++ +++E ++ R + + E + + A LE SAL + + ++ ++
Sbjct: 1234 QNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVER 1293
Query: 1036 LASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKI 1078
+L S + ++ + L ++ E + +++ER E++ L++++
Sbjct: 1294 TQTLESKAFQE---KEQLRSKLEEMYEERERTSQEMEMLRKQV 1333
Score = 68.2 bits (165), Expect = 5e-11
Identities = 144/707 (20%), Positives = 293/707 (41%), Gaps = 127/707 (17%)
Query: 554 PKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKR 613
P E+ R+K+K+ + F +M KS E++++ +EK+
Sbjct: 400 PPESFLTRDKKKTNYMEYFQEAMLFFKKS----------------EQEKKSLIEKVTQLE 443
Query: 614 KLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLL 673
L + E+ +S+K + + +E +I++L+ +E R F E + D L
Sbjct: 444 DLTLKKEKFIQSNK---------MIVKFREDQIIRLEKLHKES---RGGFLPEEQ--DRL 489
Query: 674 AEKEKFEEERLREQQEIELQKKR--------QEEETFLRVQEELQRLKELNNNEKAEKFQ 725
+ + E + LREQ E + + +EE LR+ E ++R +E++ A+ +
Sbjct: 490 LSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPVKRAQEMDAQTIAKLEK 549
Query: 726 IFQELDQLQK-EKDEQYAKLELEKK-----RLEEQEKEQVMLVAHLEEQLREKQEMIQLL 779
F E+ ++K +K++Q + +K+ E+ + + + + L +E +E +L
Sbjct: 550 AFSEISGMEKSDKNQQGFSPKAQKEPCLFANTEKLKAQLLQIQTELNNSKQEYEEFKELT 609
Query: 780 RRGEVQWVEEEKRDLEGIRESLLRVKEA-RAGGDEDGEELEK----------AQLRFFEF 828
R+ +++ +E E + L+ +L + EA +A ++ +L K + ++
Sbjct: 610 RKRQLE-LESELQSLQKANLNLENLLEATKACKRQEVSQLNKIHAETLKIITTPTKAYQL 668
Query: 829 KRRQLVKL---------VNLEKDLVQQKDILKKEVQEE------QEILECLKCEHDKESR 873
R + KL + + + DIL + V E + I E L+ ++ S
Sbjct: 669 HSRPVPKLSPEMGSFGSLYTQNSSILDNDILNEPVPPEMNEQAFEAISEELRTVQEQMSA 728
Query: 874 LLEKHDESVTDVTEVPQDFEKIKP---------VEYRLQYKERQLQYLLQ-NHLPTLLEE 923
L K DE ++ Q +K++ R+ + ++Q + L Q N L L+E
Sbjct: 729 LQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQLQE 788
Query: 924 KQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQE 983
Q + L L L+ +KE+ + + + ++ NQ ++ E ++ Q
Sbjct: 789 TQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFK--TNQEKEFNKLSERHMHVQLQL 846
Query: 984 EKVRKKEKEILESRE-------------KQQREALERALARLERRHSALQRHSTLGMEI- 1029
+ +R + +++LES+ K + + L R L ++ + L+ ME+
Sbjct: 847 DNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELL 906
Query: 1030 ---EEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQK 1086
+E+ KL+ +E S + E EK +E + E Q K VQK
Sbjct: 907 EAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAK--------VQK 958
Query: 1087 DHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCSTSAD 1146
L + SSL S + D ++ A ++ ++Q+L + E T D
Sbjct: 959 LEESLLATEKVISSLEKSRDS-------DKKVVA----DLMNQIQELRTSVCEKTET-ID 1006
Query: 1147 TMKD-----NEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISI 1188
T+K N K ++ + R + R++ + + DLK+ +++ I
Sbjct: 1007 TLKQELKDINCKYNSALVDR--EESRVLIKKQEVDILDLKETLRLRI 1051
Score = 60.8 bits (146), Expect = 8e-09
Identities = 145/739 (19%), Positives = 291/739 (39%), Gaps = 89/739 (12%)
Query: 332 IATISPADVNYGETLSTLRYANRAKNIINKPT---INEDANVKLIRELRAEIARLKTLLA 388
+ +SP ++G +L T + +I+N+P +NE A + ELR ++ L A
Sbjct: 673 VPKLSPEMGSFG-SLYTQNSSILDNDILNEPVPPEMNEQAFEAISEELRTVQEQMSALQA 731
Query: 389 QGNQIALLDSPTALSMEE---KLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKE-- 443
+ ++ + L +++ KL+ + ++QEL W + Q L Q L K+
Sbjct: 732 KLDE----EEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQLQ 787
Query: 444 ---GIGVVLDSELPHLIGI----DDDLLSTGIILYHLKEGQT--YVGRDDASTEQDIVLH 494
L SE+ L + D +L S + K Q + + + L
Sbjct: 788 ETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLD 847
Query: 495 GLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFR--FN 552
L LE+E + L S ++ + E L++ + N
Sbjct: 848 NLRLENEKLLESKAC-------LQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLN 900
Query: 553 HPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFER--QQREELEKLE 610
+ E + ++R + L F + SK + + E + QQ +++KLE
Sbjct: 901 NLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLE 960
Query: 611 SK----RKLIEEMEEKQKSDK---AELERMQQEVETQ--RKETEIVQLQIRKQEESLKRR 661
K+I +E+ + SDK A+L QE+ T K I L+ ++ + K
Sbjct: 961 ESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYN 1020
Query: 662 SFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEE----ETFLRVQEELQRLKELNN 717
S ++ + +L +K++ + L+E + + + E E E+L L E +
Sbjct: 1021 SALVDREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASK 1080
Query: 718 NEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQ 777
+EL + + E KL +K+ +E+++ E + LE + E Q
Sbjct: 1081 KHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQ 1140
Query: 778 LLRRGE------VQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELE------KAQLRF 825
+ + +E +++++E R S ++ +ED E K QLR
Sbjct: 1141 SPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLRE 1200
Query: 826 FEFKRRQLVKLVNLEKDLVQQKDILKKEVQE-EQEILECLKCEHDKESRLLEKHDES--V 882
E R + +L+ L Q D +K++ + +Q + + ++++E + E+ +S V
Sbjct: 1201 MENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIV 1260
Query: 883 TDVTEVPQDFEKIKPVEYR-----------------LQYKERQLQYLLQNHLPTLLEEKQ 925
++ ++ D E+++ Y L+ K Q + L++ L + EE++
Sbjct: 1261 EEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERE 1320
Query: 926 RAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEK 985
R + ++ + K++E E+ + + N QK+Q R E+
Sbjct: 1321 RTSQEME-----------MLRKQVECLAEENGKLVGHQNLHQKIQYVVRLKKENVRLAEE 1369
Query: 986 VRKKEKEILESREKQQREA 1004
K E + +EK++ E+
Sbjct: 1370 TEKLRAENVFLKEKKRSES 1388
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 283 bits (723), Expect = 1e-75
Identities = 261/860 (30%), Positives = 413/860 (48%), Gaps = 141/860 (16%)
Query: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFY 63
VKVAVR+RP +EK +E I T++T + P+ G + K FTYDF F
Sbjct: 9 VKVAVRIRPQLSKEK-IEGCHIC------TSVTPGE-PQVLLG-----KDKAFTYDFVF- 54
Query: 64 SADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTM------MGNSG 117
DT QE ++ T + +++ FEGYNA V AYGQTG+GK+YTM +
Sbjct: 55 DLDTW------QEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEE 108
Query: 118 DSGLIPRICEGLFSRINETTRWDEAS------FRTEVSYLEIYNERVRDLLRRKSS---- 167
+ G+IPR LF I E R + F+ +LE+YNE + DL
Sbjct: 109 EQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTR 168
Query: 168 -KTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAI 226
+ N+++ E G Y ++ L+ + ++ + + G ++RTTA+T MN SSRSHAI
Sbjct: 169 HRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAI 228
Query: 227 FTIKFTQAKFDSE----------MPCET---------VSKIHLVDLAGSERADATGATGV 267
FTI Q + ++ +P T +K H VDLAGSER TGATG
Sbjct: 229 FTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGE 288
Query: 268 RLKEGGNINKSLVTLGNVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNS 327
R KEG +IN L+ LGNVISAL D S KK V VPYRDS LT LL+DSLGGNS
Sbjct: 289 RAKEGISINCGLLALGNVISALGDQS---------KKVVHVPYRDSKLTRLLQDSLGGNS 339
Query: 328 KTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLL 387
+TIMIA +SP+D ++ ETL+TL+YANRA+NI NK +N+D + I LRAEIARL+ L
Sbjct: 340 QTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMEL 399
Query: 388 AQ---GNQIALLDSPTALS---MEEKLQQNE--------ARVQELTKEWTNKWNETQNIL 433
+ G ++ D S E + Q E +QE N+ TQ +
Sbjct: 400 MEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNR--VTQLMS 457
Query: 434 KEQTLALRK-----EGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTE 488
+E L L K E IG ++ + + + + LL + + L+ + R A +
Sbjct: 458 QEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRS---LSRASARSP 514
Query: 489 QDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNM 548
++G + GS S + +A+ + + A L R
Sbjct: 515 Y-----------------SLGASPAAPAFGGSPAS----SMEDASEVIRRAKQDLERLKK 553
Query: 549 FRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEK 608
+++ + +K L + TD +++ E G E E + +E E
Sbjct: 554 KEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEE--RDESGCEEEEGREDEDED 611
Query: 609 LESKRKLIE---EMEEKQKSDKAELERMQQEVETQRK---ETEIVQLQIRKQEESLKRRS 662
S+ L++ + EEK+ + +A+L + E+E ++K E E Q +++ + + +
Sbjct: 612 SGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKL 671
Query: 663 FHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAE 722
++NK++D E++ R Q + + EE+ + +RL+E+N +
Sbjct: 672 ILLQNKIRDTQLERD-------RVLQNLSTMECYTEEKANKIKADYEKRLREMNRD---- 720
Query: 723 KFQIFQELDQLQKE-----KDEQYAKLELEKKRLE--EQEKEQVMLVAHLEEQLREKQEM 775
Q+L QKE K++ + EL+K + E E +K +V L+ + E+ ++++ +
Sbjct: 721 ----LQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREE-QQRRRL 775
Query: 776 IQLLRRGEVQWVEEEKRDLE 795
++ R E+ +++E+R E
Sbjct: 776 VETKRNREIAQLKKEQRRQE 795
Score = 58.2 bits (139), Expect = 5e-08
Identities = 156/743 (20%), Positives = 298/743 (40%), Gaps = 90/743 (12%)
Query: 386 LLAQGNQIALL-------------DSPTALSMEEKLQQNEARVQELTKEWTNK-WNETQN 431
LLA GN I+ L DS +++ L N + +++ + ET N
Sbjct: 300 LLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 359
Query: 432 ILKEQTLALR-KEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQD 490
LK A K + V D + + ++ + L K G+ +G D A D
Sbjct: 360 TLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSD 419
Query: 491 IVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTN--- 547
+ L+ E+ G + L + Q +++ + ++Q A +LL +
Sbjct: 420 LFRENAMLQKEN-------GALRL-RVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGN 471
Query: 548 ----MFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQR 603
N+ +E +LR K LL S +++ + L +S SA Y+ G
Sbjct: 472 EAIGALIQNYIREIEELRTK----LLESEAMNES-LRRSLSRASARSPYSLGASPAAPAF 526
Query: 604 EELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSF 663
S +E+ E + K +LER++++ QR+++ ++E KR
Sbjct: 527 GG-----SPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSP-------EKEAFKKRAKL 574
Query: 664 HIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEEL----QRLKELNNNE 719
EN + E E+ EEE R++ E ++ R++E+ +E L +E N
Sbjct: 575 QQENSEETDENEAEEEEEE--RDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNF 632
Query: 720 KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLE----EQEKEQVMLVAHLEEQLREKQEM 775
+A+ + E++ QK DE LE ++RL+ + E++ ++L + + E+ +
Sbjct: 633 QADLADLTCEIEIKQKLIDE----LENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRV 688
Query: 776 IQLLRRGEVQWVEEE----KRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRR 831
+Q L E + EE+ K D E + R + ++ L K Q R+ R
Sbjct: 689 LQNLSTMEC-YTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRY----ER 743
Query: 832 QLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQD 891
+L KL ++ + K L K+++EEQ+ ++ + ++E L+K E ++
Sbjct: 744 ELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKK--EQRRQEFQIRAL 801
Query: 892 FEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAF---EILDRG-PLSLDNTLYQVEK 947
+ + E L+ K +++ L + P RA +LD G +S T + E
Sbjct: 802 ESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAES 861
Query: 948 EMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALER 1007
+ Q+ N +++ +K + + + ++LER
Sbjct: 862 GARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLER 921
Query: 1008 ALARLERRHSALQRHSTLGMEIE-----EQRQKLASLNSGSREQSGLQASLEAEQEALEK 1062
+ + +QR + + +E + ++R++L L R + + L+AE EK
Sbjct: 922 RIIDI-----VMQRMTIVNLEADMERLIKKREELFLLQEALRRK---RERLQAESPEEEK 973
Query: 1063 DQERLEYEIQQLKQKI-YEVDGV 1084
+ L EI+ L I Y DG+
Sbjct: 974 GLQELAEEIEVLAANIDYINDGI 996
Score = 37.0 bits (84), Expect = 0.12
Identities = 80/442 (18%), Positives = 172/442 (38%), Gaps = 72/442 (16%)
Query: 562 EKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGL---------EFERQQREELEKLESK 612
E++ + + + + + ++++ + L A + L E ++ Q E E ++K
Sbjct: 700 EEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAK 759
Query: 613 RKLIEEMEEKQKSDK-------AELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHI 665
L+++M E+Q+ + E+ ++++E Q + ++ Q R+QE L+R++ +
Sbjct: 760 VALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEV 819
Query: 666 E------NKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRL--KELNN 717
+ + +A + + L E+ E E+ R + R +++N+
Sbjct: 820 SALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINH 879
Query: 718 -------------NEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAH 764
+KFQ K ++ LE + Q V L A
Sbjct: 880 FLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEAD 939
Query: 765 LEEQLREKQEMIQL---LRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKA 821
+E +++++E+ L LRR + E + +G++E ++ A D + +
Sbjct: 940 MERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDC 999
Query: 822 QLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKH-DE 880
Q +V LE+ K+E+ + C + LL+
Sbjct: 1000 Q-----------ATIVQLEE--------TKEELDSTDTSVVISSCSLAEARLLLDNFLKA 1040
Query: 881 SVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNH-LPTLLEEKQRAFEILDRGPLSLD 939
S+ +V Q +I+ +E RL ++ + QNH L L EK A L
Sbjct: 1041 SIDKGLQVAQKEAQIRLLEGRL--RQTDMAGSSQNHLLLDALREKAEAHP-------ELQ 1091
Query: 940 NTLYQVEKE--MEEKEEQLAQY 959
+Y V++E +E+++++
Sbjct: 1092 ALIYNVQQENGYASTDEEISEF 1113
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 272 bits (696), Expect = 1e-72
Identities = 320/1205 (26%), Positives = 527/1205 (43%), Gaps = 164/1205 (13%)
Query: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61
+SV+VAVR+RP +EK +E I T++T + P+ G + K FT+D+
Sbjct: 8 SSVRVAVRIRPQLAKEK-IEGCHIC------TSVTPGE-PQVFLG-----KDKAFTFDYV 54
Query: 62 FYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS-- 119
F D S QE ++ +++ FEGYNA VFAYGQTG+GK+YTM G D
Sbjct: 55 F---DIDS----QQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNI 106
Query: 120 -----GLIPRICEGLFSRINETTR------WDEASFRTEVSYLEIYNERVRDLLRRK--- 165
G+I R + LF I E F+ +LE+YNE V DL
Sbjct: 107 VEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDI 166
Query: 166 --SSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRS 223
SK N+R+ E G Y ++ V ++ + + G ++RTTA+T MN SSRS
Sbjct: 167 DAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRS 226
Query: 224 HAIFTIKFTQAKFDSEMPCETVS-------------------KIHLVDLAGSERADATGA 264
HAIFTI Q + ++ + + K H VDLAGSER TGA
Sbjct: 227 HAIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGA 286
Query: 265 TGVRLKEGGNINKSLVTLGNVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLG 324
TG R KEG +IN L+ LGNVISAL D S K+ VPYRDS LT LL+DSLG
Sbjct: 287 TGERAKEGISINCGLLALGNVISALGDKS---------KRATHVPYRDSKLTRLLQDSLG 337
Query: 325 GNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLK 384
GNS+TIMIA +SP+D ++ ETL+TL+YANRA+NI NK +N+D + I LR+EI RL+
Sbjct: 338 GNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQ 397
Query: 385 -TLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKE 443
L+ ++D S+ + +N E N ++E ALR
Sbjct: 398 MELMEYKTGKRIIDEEGVESINDMFHENAMLQTE-----NNNLRVRIKAMQETVDALRSR 452
Query: 444 GIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIV-LHGLDLESEH 502
+V D +L EG + S ++I L LESE
Sbjct: 453 ITQLVSD--------------QANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESE- 497
Query: 503 CIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQG----AVILLGRTNMFRFNHPKEAA 558
+ EN+ +T S G T L+ +I L + ++ E
Sbjct: 498 AVNENLRKNLTRATARAPYFS--GSSTFSPTILSSDKETIEIIDLAKKDL-------EKL 548
Query: 559 KLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEE 618
K +EKRK ++ TD + ++ V E E + E E E EE
Sbjct: 549 KRKEKRKKKSVAG-KEDNTDTDQEKKEEKGVS------ERENNELEVEESQEVSDHEDEE 601
Query: 619 MEEKQKSDKAELERMQQEVETQRKETEIVQLQIRK--QEESLKRRSF-HIENKLKDLLAE 675
EE+++ D + E +++ E Q + E ++K++ +EN K L
Sbjct: 602 EEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTL 661
Query: 676 KEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRL--KELNNNEKAEKFQIFQELDQL 733
K+++EE+ + Q +I +T L + LQ L E + EKA+K +
Sbjct: 662 KKQYEEKLMMLQHKI--------RDTQLERDQVLQNLGSVESYSEEKAKK---------V 704
Query: 734 QKEKDEQYAKLELEKKRLEEQEKEQVMLV---AHLEEQLREKQEMIQLLRRGEVQWVEEE 790
+ E +++ + E +RL+ +KE L+ + E+QL++ Q+ + +++ +V+ +++
Sbjct: 705 RSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQM 764
Query: 791 KRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDIL 850
K + E R + E E AQL+ + KR ++L+ +K Q+ +L
Sbjct: 765 KEEQEKARLT------------ESRRNREIAQLKKDQRKRDHQLRLLEAQKR--NQEVVL 810
Query: 851 KKEVQEEQEILECLKCEHDK-ESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKER-Q 908
+++ +E + ++ DK ++ K S + ++ R +++ +
Sbjct: 811 RRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMR 870
Query: 909 LQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQK 968
+ LPT R + +G L ++ + K K + L + + +
Sbjct: 871 IPVARVQALPTPATNGNRK-KYQRKG---LTGRVF-ISKTARMKWQLLERRVTDIIMQKM 925
Query: 969 LQATFEFTAN-IARQEEKVRKKEKEILESREKQQREALE--RALARL-ERRHSALQRHST 1024
+ E N + +Q E++ K+ +++ + REK +E E + +A + E S
Sbjct: 926 TISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDY 985
Query: 1025 LGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGV 1084
+ I + + + + E L + L + + L++ + K +
Sbjct: 986 INDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINK--GLQAA 1043
Query: 1085 QKDHH-GTLEGKVASSSLPVSAEKSHLVPLM--DARINAYIEEEVQRRLQDLHRVISEGC 1141
QK+ LEG++ + + + + L ++ A +N ++ + LQDL V E
Sbjct: 1044 QKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENV 1103
Query: 1142 STSAD 1146
S D
Sbjct: 1104 EDSTD 1108
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 264 bits (675), Expect = 4e-70
Identities = 221/710 (31%), Positives = 338/710 (47%), Gaps = 128/710 (18%)
Query: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
++KV R RP++R+E+ + I+ M+ +T L+ P G E KTFT+D +
Sbjct: 10 ALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVT-LRNPRAAPG----ELPKTFTFD-AV 63
Query: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
Y A +K D + + ++ S +G+N VFAYGQTG+GK+YTM G +
Sbjct: 64 YDASSKQADLYDETV------RPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELR 117
Query: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
G+IP E +F+ I+ R + SYLEIY E +RDLL ++ K L ++E+P+
Sbjct: 118 GVIPNAFEHIFTHIS---RSQNQQYLVRASYLEIYQEEIRDLLSKEPGK--RLELKENPE 172
Query: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIF--TIKFTQAKFD 237
G Y++DLS + +N ++E +M+ GN R +T MN+VSSRSHAIF T++ ++ D
Sbjct: 173 TGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSD 232
Query: 238 SEMPCETVSKIHLVDLAGSERADATG------------------------ATGVRLKEGG 273
+ V K++LVDLAGSER + G A G R KE
Sbjct: 233 GQDHIR-VGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEAS 291
Query: 274 NINKSLVTLGNVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIA 333
IN SL LGNVI+ALA + +PYRDS LT LL+DSLGGN+KTIM+A
Sbjct: 292 KINLSLSALGNVIAALAG-----------NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVA 340
Query: 334 TISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQI 393
T+ PA +Y E+LSTLR+ANRAKNI NKP +NED L+RE + EIARLK L + +
Sbjct: 341 TLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGML 400
Query: 394 ALLDSPTALSMEEKLQQN-----------EARVQELTKEWTNKWNETQNILKEQTLALRK 442
P S K + EA V E + N Q IL+ AL K
Sbjct: 401 G--KRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILES---ALEK 455
Query: 443 EGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLHGLD----L 498
+ +L+E + + + A+ + D L + L
Sbjct: 456 N-------------------------MENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLL 490
Query: 499 ESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAA 558
E + + E++ + +++ A + + +L+G N+ +H E
Sbjct: 491 EEKEKMLEDL------------RREQQATELLAAKYKAMESKLLIGGRNI--MDHTNEQQ 536
Query: 559 KLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYN-PGLEFERQQREELEKLESKRKLIE 617
K+ E ++ + + RE +ML + +E +++E K K ++
Sbjct: 537 KMLELKRQEIAE-------QKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLK 589
Query: 618 EMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIEN 667
++ K ++ KAE++ E R++ E Q +Q LK + IEN
Sbjct: 590 KLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQ---NEQTRELKLKYLIIEN 636
Score = 55.5 bits (132), Expect = 3e-07
Identities = 48/185 (25%), Positives = 92/185 (49%), Gaps = 18/185 (9%)
Query: 599 ERQQREELEKLESKRKLIEE-----MEEKQKSDKAELERMQQEVETQRKETEIVQLQIRK 653
E +E+ E+LE ++ I++ EEKQK + E E+M +++ +++ TE++ + +
Sbjct: 458 ENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLE-EKEKMLEDLRREQQATELLAAKYKA 516
Query: 654 QEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLK 713
E L +I D E++K E + +QEI QK+R+ E +Q+E+
Sbjct: 517 MESKLLIGGRNI----MDHTNEQQKMLELK---RQEIAEQKRRERE-----MQQEMMLRD 564
Query: 714 ELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQ 773
E + + QE++ K+ + YAKL+ K +++Q E + + LEE E+
Sbjct: 565 EETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQT 624
Query: 774 EMIQL 778
++L
Sbjct: 625 RELKL 629
Score = 36.6 bits (83), Expect = 0.16
Identities = 47/180 (26%), Positives = 84/180 (46%), Gaps = 17/180 (9%)
Query: 665 IENKLKDLLAE-KEKFEEERLREQQEIEL-----QKKRQEEETFLR-VQEELQRLKELNN 717
+E +++ L E KE+ EEE+ Q + L QK +E+E L ++ E Q + L
Sbjct: 453 LEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAA 512
Query: 718 NEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEM-I 776
KA + ++ + +EQ LEL+++ + EQ++ + + E LR+++ M +
Sbjct: 513 KYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREM--QQEMMLRDEETMEL 570
Query: 777 QLLRRGEVQWVEEEKRDLEGIRESLLRVK-EARAGGDE------DGEELEKAQLRFFEFK 829
+ Q VE + + L+ + L VK E + DE D EE + Q R + K
Sbjct: 571 RGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLK 630
Score = 35.4 bits (80), Expect = 0.36
Identities = 29/144 (20%), Positives = 69/144 (47%), Gaps = 14/144 (9%)
Query: 909 LQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKE--MEEKEEQLAQYQANANQL 966
L+ L+ ++ L+E++ E ++ + D +L EK+ +EEKE+ L +
Sbjct: 449 LESALEKNMENYLQEQKERLEE-EKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQAT 507
Query: 967 QKLQATFEFTA--------NI---ARQEEKVRKKEKEILESREKQQREALERALARLERR 1015
+ L A ++ NI +++K+ + +++ + +++++RE + + R E
Sbjct: 508 ELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEET 567
Query: 1016 HSALQRHSTLGMEIEEQRQKLASL 1039
+++L E+E + +KL L
Sbjct: 568 MELRGTYTSLQQEVEVKTKKLKKL 591
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 259 bits (661), Expect = 2e-68
Identities = 270/960 (28%), Positives = 435/960 (45%), Gaps = 128/960 (13%)
Query: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
S+KV R RP+N E KFI + + +T + P
Sbjct: 8 SIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKP--------------------- 46
Query: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
Y D P +QE V+ +VK EGYN +FAYGQT SGK++TM G D
Sbjct: 47 YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106
Query: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
G+IPRI +F I + F +VSY EIY +++RDLL SKT NL V E
Sbjct: 107 GIIPRIAHDIFDHIYSMD--ENLEFHIKVSYFEIYLDKIRDLL--DVSKT-NLAVHEDKN 161
Query: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSE 239
PYV+ ++ V + +V +++D G NR A T MN+ SSRSH+IF I Q ++E
Sbjct: 162 RVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETE 221
Query: 240 MPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANT 299
K++LVDLAGSE+ TGA G L E NINKSL LGNVISALA+ ++
Sbjct: 222 KKLS--GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK----- 274
Query: 300 LAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNII 359
VPYRDS +T +L+DSLGGN +T ++ SP+ N ET STL + RAK I
Sbjct: 275 ------THVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIK 328
Query: 360 NKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARV---Q 416
N ++N EL AE + K + L + L ME +N V +
Sbjct: 329 NTVSVN--------LELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDE 380
Query: 417 ELTKEWTNKWNETQNILKEQTLALRKEGIGV----VLDSELPHLI----GIDDDLLSTGI 468
+++ + N +A GI D E+ L DD++
Sbjct: 381 QISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQ 440
Query: 469 ILYHLKEGQTYVGRDD--ASTEQDI-----VLHGLDLESEHCIFENIGGTVTLIPLSGSQ 521
+ LK Q + +D+ AST +D L L +E+E + + + +
Sbjct: 441 LAEKLK--QQMLDQDELLASTRRDYEKIQEELTRLQIENE-AAKDEVKEVLQALEELAVN 497
Query: 522 CSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLRE---KRKSGLLSSFSLSMTD 578
++ + T N+ L + +E ++L+E +K +L + D
Sbjct: 498 YDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKD 557
Query: 579 LSK-----SRENLSAVMLYNPGLEFE-RQQREELEKLESKRKLIEEMEEKQKSDKAELER 632
L + ++ + N +E E R + K++S+ K + ++ +S + + R
Sbjct: 558 LGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNR 617
Query: 633 MQQEVETQRKETEIVQLQIRKQEESLKRRSFHIEN---KLKDLLAEKEKFEEE--RLREQ 687
++ +E QL I + E +K + +++N K + L ++ EE +LR Q
Sbjct: 618 ---KMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQ 674
Query: 688 Q---EIELQKKRQEEETFLRVQEELQRL--KELNNNEKAEKFQIFQ---ELDQLQKEKDE 739
+ E+ Q K +E T L+ EE+++ +++ ++ +A + Q+ + E+++ QK DE
Sbjct: 675 EKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDE 734
Query: 740 ---QYAKLELEKKRL---------EEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWV 787
KL+LE+++L E+QE+E + L L +K+E + +G + V
Sbjct: 735 IRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLL---LNDKREQAREDLKGLEETV 791
Query: 788 EEEKRDLEGIRESLL-----RVKEARAGGDED--GEELEKAQLRFFEFKRRQLVK----L 836
E + L +R+ + RVK++ ++D G +K ++ F E QL K L
Sbjct: 792 SRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQL 851
Query: 837 VNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIK 896
V DL + L+K ++ E ++ L ES L E + ++ D Q+ ++IK
Sbjct: 852 VRDNADLRCELPKLEKRLRATAERVKAL------ESALKEAKENAMRDRKRYQQEVDRIK 905
Score = 78.6 bits (192), Expect = 4e-14
Identities = 136/606 (22%), Positives = 254/606 (41%), Gaps = 86/606 (14%)
Query: 610 ESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIV---QLQIRKQEESLKRRSFHIE 666
E +K E+ +EK K+ K ++ ++ E+ R + Q+ + Q+ + I
Sbjct: 340 EEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPII 399
Query: 667 NKLKDLLA-----EKEKFEEE-------------RLREQQEIELQKKRQ----------E 698
+ + ++A EKEK++EE + +Q ++ + K+Q
Sbjct: 400 DNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLAST 459
Query: 699 EETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQ 758
+ ++QEEL RL+ N K E ++ Q L++L D++ ++E +K R EQ ++
Sbjct: 460 RRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVE-DKTRANEQLTDE 518
Query: 759 V----MLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDED 814
+ + + +L + QE+ ++ + + +DL G ++ + + D +
Sbjct: 519 LAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDL-GEIGGIIGTNDVKTLADVN 577
Query: 815 G---EELEKAQLRFFEFKRRQLVKLVNLEKDLVQ-QKDILKKEVQEEQEILECLKCEHDK 870
G EE A+L + K ++ LVN K L Q D +K E+E+ C
Sbjct: 578 GVIEEEFTMARLYISKMK-SEVKSLVNRSKQLESAQMDSNRKMNASERELAAC------- 629
Query: 871 ESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEI 930
L+ +H+ + +T+ Q+ E + R Q +E Q L + +EK
Sbjct: 630 -QLLISQHEAKIKSLTDYMQNME-----QKRRQLEESQ-DSLSEELAKLRAQEKMHEVSF 682
Query: 931 LDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKE 990
D+ L T Q +EM++ EQ + A+Q Q ++R +++ +K+
Sbjct: 683 QDKEKEHL--TRLQDAEEMKKALEQQMESHREAHQKQ-----------LSRLRDEIEEKQ 729
Query: 991 KEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQS--- 1047
K I E R+ Q+ LE+ E+ S + E E + +KL LN REQ+
Sbjct: 730 KIIDEIRDLNQKLQLEQ-----EKLSSDYNKLKIEDQEREMKLEKLLLLND-KREQARED 783
Query: 1048 --GLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSA 1105
GL+ ++ E + L ++ ++ +K E+D D G+ K S L +
Sbjct: 784 LKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELD--NDDGGGSAAQKQKISFLENNL 841
Query: 1106 EKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKLKY 1165
E+ V R NA + E+ +L+ R +E +K E N RK +Y
Sbjct: 842 EQLTKVHKQLVRDNADLRCELP-KLEKRLRATAERVKALESALK--EAKENAMRDRK-RY 897
Query: 1166 ERMVSR 1171
++ V R
Sbjct: 898 QQEVDR 903
Score = 66.2 bits (160), Expect = 2e-10
Identities = 96/538 (17%), Positives = 233/538 (43%), Gaps = 75/538 (13%)
Query: 597 EFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEE 656
+ ++Q ++ E L S R+ E+++E EL R+Q E E + E + V + +
Sbjct: 444 KLKQQMLDQDELLASTRRDYEKIQE-------ELTRLQIENEAAKDEVKEVLQALEELAV 496
Query: 657 SLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELN 716
+ ++S +E+K R EQ EL Q+ T Q EL +L+EL+
Sbjct: 497 NYDQKSQEVEDK-------------TRANEQLTDEL---AQKTTTLTTTQRELSQLQELS 540
Query: 717 NNEKAEKFQIF-------------------QELDQLQKEKDEQYAKLELEKKRLEEQEKE 757
N++K +I + L + +E++ L +++ + K
Sbjct: 541 NHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKS 600
Query: 758 QVMLVAHLEEQLREKQEMIQLLRRGEVQ---WVEEEKRDLEGIRESLLRVKEARAGGDED 814
V LE + + R + + + ++ + + + +++ R +E
Sbjct: 601 LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEES 660
Query: 815 GEELEKAQLRFFEFKRRQLVKLVNLEKD---LVQQKDILKKEVQEEQEILECLKCEHDKE 871
+ L + + ++ V + EK+ +Q + +KK ++++ +E + H K+
Sbjct: 661 QDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQ---MESHREAHQKQ 717
Query: 872 -SRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEI 930
SRL + ++ E + ++I+ + +LQ ++ +L ++ +E+++R ++
Sbjct: 718 LSRLRD-------EIEEKQKIIDEIRDLNQKLQLEQEKLS---SDYNKLKIEDQEREMKL 767
Query: 931 LDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKE 990
L L++ Q ++++ EE +++ + L+KL F ++ + +K + +
Sbjct: 768 --EKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKL-----FVQDLTTRVKKSVELD 820
Query: 991 KEI--LESREKQQREALERALARLERRHSALQR-HSTLGMEIEEQRQKLASLNSGSREQS 1047
+ + +KQ+ LE L +L + H L R ++ L E+ + ++ L + +
Sbjct: 821 NDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKR---LRATAERVK 877
Query: 1048 GLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSA 1105
L+++L+ +E +D++R + E+ ++K+ + + ++ H + + P S+
Sbjct: 878 ALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASS 935
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 257 bits (656), Expect = 6e-68
Identities = 268/978 (27%), Positives = 454/978 (46%), Gaps = 115/978 (11%)
Query: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
+++V VR RP N E+ A I++ + + ++ + GG D + KT+T+D F
Sbjct: 18 NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVS---VRTGGLAD--KSSRKTYTFDMVF 72
Query: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
A TK D V++++ ++ GYN +FAYGQTG+GK++TM G +
Sbjct: 73 -GASTKQID------VYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEY 125
Query: 120 --------GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFN 171
G+IPR +F ++ + + F +VS LEIYNE + DLL S +
Sbjct: 126 TWEEDPLAGIIPRTLHQIFEKLTD----NGTEFSVKVSLLEIYNEELFDLLNPSSDVSER 181
Query: 172 LRVREHP--KEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIF-- 227
L++ + P K G ++ L + V N +V ++++ G RTTAAT MN SSRSH++F
Sbjct: 182 LQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSV 241
Query: 228 TIKFTQAKFDSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVIS 287
TI + D E + + K++LVDLAGSE +GA R +E GNIN+SL+TLG VI+
Sbjct: 242 TIHMKETTIDGEELVK-IGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT 300
Query: 288 ALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLS 347
AL + + VPYR+S LT +L+DSLGG ++T +IATISPA +N ETLS
Sbjct: 301 ALVE------------RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLS 348
Query: 348 TLRYANRAKNIINKPTINEDANVK-LIRELRAEIARLKTLLAQGNQI--ALLDSPTALSM 404
TL YA+RAKNI+NKP +N+ K LI+E EI RLK LA + + M
Sbjct: 349 TLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVM 408
Query: 405 EEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLL 464
KL E ++ EL E E N + E + + E LD L +L
Sbjct: 409 SGKLTVQEEQIVELI-EKIGAVEEELNRVTELFMDNKNE-----LDQCKSDLQNKTQELE 462
Query: 465 STGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTV--TLIPLSGSQC 522
+T HL+E + + +++ T L + E H + TV T +SG
Sbjct: 463 TT---QKHLQETKLQLVKEEYITS---ALESTE-EKLHDAASKLLNTVEETTKDVSGLHS 515
Query: 523 SVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAK--------LREKRKS--GLLSSF 572
++ + V+ N A + G+ FN+ +E K + E K+ G L S
Sbjct: 516 KLDRKKAVD--QHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSS 573
Query: 573 SLSMTD---------LSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQ 623
S+S D L+ EN+S + F +E+ ESK +++E+
Sbjct: 574 SVSALDTITTVALGSLTSIPENVST----HVSQIFNMILKEQSLAAESK-TVLQELINVL 628
Query: 624 KSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEE-- 681
K+D + +E T + L+I Q + + + S + +K++D E + F
Sbjct: 629 KTD------LLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSIL 682
Query: 682 -ERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQ 740
L E QE + + ++ + E+L+ +K+ ++ E + ++ E +EK E
Sbjct: 683 CNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQELCKLMNLWTERFCALEEKCEN 742
Query: 741 YAK-LELEKKRLEEQEKEQV-MLVAHLEEQLREKQEMIQLLR---RGEVQWVEEEKRDLE 795
K L ++ ++++ K+ V + H ++ + Q LR + + VEE + +
Sbjct: 743 IQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEESVKHSD 802
Query: 796 GIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKK--- 852
+ +L ++ + E + E R F + + L E++L +++ +
Sbjct: 803 KLNGNLEKISQ------ETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCE 856
Query: 853 -EVQEEQEILECLKCEHDKESRLLEKHDESVTDVTE-VPQDFEKIKPVEYRLQYKERQLQ 910
+ E + K H+K+ + D+ D + + Q+ E + ++ L L+
Sbjct: 857 ASSSDITEKSDGRKAAHEKQHNIF--LDQMTIDEDKLIAQNLELNETIKIGLTKLNCFLE 914
Query: 911 YLLQNHLPTLLEEKQRAF 928
L+ +PT +++++
Sbjct: 915 QDLKLDIPTGTTPQRKSY 932
Score = 50.4 bits (119), Expect = 1e-05
Identities = 114/571 (19%), Positives = 229/571 (40%), Gaps = 75/571 (13%)
Query: 658 LKRRSFHIENKLKDLLAEKEK----FEEERLREQQ-EIELQKKRQEE--ETFLRVQEELQ 710
+K + IE +DL A +EK EE R ++ +Q+++ E E V+EEL
Sbjct: 375 IKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELN 434
Query: 711 RLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLR 770
R+ EL + K ELDQ + + + +LE +K L+E K Q++ ++ L
Sbjct: 435 RVTELFMDNK-------NELDQCKSDLQNKTQELETTQKHLQE-TKLQLVKEEYITSALE 486
Query: 771 EKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKR 830
+E + + VEE +D+ G+ L R K D+ E + +
Sbjct: 487 STEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAV----DQHNAEAQ-------DIFG 535
Query: 831 RQLVKLVNLEKDLVQQKDILKKEVQEEQEIL--ECLKCEHDKESRLLEKHDESVTDV--- 885
+ L L N ++L++ +K + E + L L + S+T +
Sbjct: 536 KNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPEN 595
Query: 886 --TEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLY 943
T V Q F I + + LQ L+ LL + L +++ L
Sbjct: 596 VSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLK 655
Query: 944 QVEK-------EMEEKEEQLAQY-QANANQLQKLQATFEFTANIARQEEKVRKKEKEILE 995
+ K ++E+++++L + N L +LQ E T + +K E L+
Sbjct: 656 HIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQ---ENTICSLVESQKQCGNLTEDLK 712
Query: 996 SREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQS-GLQASLE 1054
+ ++ + L + + R AL+ + E ++ L+S+ +++S + +
Sbjct: 713 TIKQTHSQELCKLMNLWTERFCALEE------KCENIQKPLSSVQENIQQKSKDIVNKMT 766
Query: 1055 AEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLM 1114
+ D + E++ Q+ ++ H L G + +S E +
Sbjct: 767 FHSQKFCADSDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEK----ISQETEQRCESL 822
Query: 1115 DARINAYIEE------EVQRRLQDLHRVISEGCSTSADTMKD--------NEKLHNGTI- 1159
+ R + E+ E ++ L +L V+S+ C S+ + + +EK HN +
Sbjct: 823 NTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLD 882
Query: 1160 QRKLKYERMVSRSLGANPDDLKDPIKISIPR 1190
Q + +++++++L +L + IKI + +
Sbjct: 883 QMTIDEDKLIAQNL-----ELNETIKIGLTK 908
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 254 bits (648), Expect = 5e-67
Identities = 264/962 (27%), Positives = 427/962 (44%), Gaps = 137/962 (14%)
Query: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
S+KV R RP+N+ E KFI + + + GG K + +D F
Sbjct: 9 SIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVI------GG---------KPYVFDRVF 53
Query: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
P +QE V+ +VK GYN +FAYGQT SGK++TM G D
Sbjct: 54 -------PPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106
Query: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
G+IPRI +F+ I + F +VSY EIY +++RDLL +KT NL V E
Sbjct: 107 GIIPRIARDIFNHIYSMD--ENLEFHIKVSYFEIYLDKIRDLL--DVTKT-NLSVHEDKN 161
Query: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSE 239
P+V+ ++ V + ++ +++D G NR A T MN+ SSRSH+IF I Q ++E
Sbjct: 162 RVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETE 221
Query: 240 MPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANT 299
K++LVDLAGSE+ TGA G L E NINKSL LGNVISALA+ ++
Sbjct: 222 QKLS--GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKS---- 275
Query: 300 LAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNII 359
+VPYRDS +T +L+DSLGGN +T M SP+ N ET STL + RAK I
Sbjct: 276 -------YVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIK 328
Query: 360 NKPTINED------------------ANVKLIRELRAEIARLK-------TLLAQGNQIA 394
N ++N + A + I +L AE++R + T G + A
Sbjct: 329 NTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAA 388
Query: 395 L---LDSPTALS---------MEEKLQQNEARVQELTKEWTNKWNE-----------TQN 431
L L T ++ E+ Q+ E ++ L K+ +K +E Q
Sbjct: 389 LGAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQ 448
Query: 432 ILKEQTLALRKEGIGVVLDSELPHLIGIDDDLL-STGIILYHLKEGQTYVGRDDASTEQD 490
+L ++ L + G + EL HL +D +L L+E V D S E
Sbjct: 449 MLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEE--LAVNYDQKSQE-- 504
Query: 491 IVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFR 550
+ +++ + E T++ L + V + + + L+ + F
Sbjct: 505 --VEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFS 562
Query: 551 FNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVM-----LYNPGLEFERQQREE 605
KL + + F+++ +SK + + +V+ L N +E R+
Sbjct: 563 VIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVT 622
Query: 606 LEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHI 665
+L S + LI + E K +S L Q VE +++ E + + L+ +
Sbjct: 623 GRELSSCQLLISQHEAKIRS----LTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVH 678
Query: 666 ENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQ 725
E LKD E + + + +++ E++++ R+ +L RL++ E EK +
Sbjct: 679 EVALKD--KEPDTQDADEVKKALELQMESHREAH------HRQLARLRD----EINEKQK 726
Query: 726 IFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQ 785
EL L ++ + KL+ + ++L+ +E E+ + L L E+ E + +G +
Sbjct: 727 TIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQEL-TFLYERHEQSKQDLKGLEE 785
Query: 786 WVEEEKRDLEGIRESLL-----RVKEARAGGDED--GEELEKAQLRFFEFKRRQLVK--- 835
V E + L +R+ + RVK++ ED G +K ++ F E QL K
Sbjct: 786 TVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHK 845
Query: 836 -LVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEK 894
LV DL + L+K ++ E ++ L E L E + ++ D Q+ ++
Sbjct: 846 QLVRDNADLRCELPKLEKRLRATAERVKAL------EGALKEAKEGAMKDKRRYQQEVDR 899
Query: 895 IK 896
IK
Sbjct: 900 IK 901
Score = 68.9 bits (167), Expect = 3e-11
Identities = 129/618 (20%), Positives = 252/618 (40%), Gaps = 101/618 (16%)
Query: 506 ENIGGTVTLIPLSGSQ----CSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLR 561
+ + G + L+ L+GS+ G + EA ++N+ ++ LG K R
Sbjct: 222 QKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINK-SLSALGNVISALAEGTKSYVPYR 280
Query: 562 EKRKSGLLSS----------FSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELE-KLE 610
+ + + +L F E S +M + LE E
Sbjct: 281 DSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAE 340
Query: 611 SKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLK 670
+K E+ +EK K+ K + +++ E+ R + + + EE+ E +
Sbjct: 341 QWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVN 400
Query: 671 DLLA--------EKEKFEEE--RLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEK 720
D + E++K+EEE RL +Q + + + Q+ + ++++++ +EL + +
Sbjct: 401 DNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTR 460
Query: 721 AEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLR 780
+ ++ +EL LQ E D AK E+ K + + +E + +++ EK + QLL
Sbjct: 461 GDNEKVQRELSHLQSENDA--AKDEV--KEVLQALEELAVNYDQKSQEVEEKSQQNQLL- 515
Query: 781 RGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVN-L 839
V + ++ + + L R++E +R+++ +++N L
Sbjct: 516 ---VDELSQKVATMLSLESELQRLQEVSG------------------HQRKRIAEVLNGL 554
Query: 840 EKDLVQQKDIL-KKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPV 898
KDL + I+ E++ EI ++ E + K V V + + E ++
Sbjct: 555 MKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVE 614
Query: 899 EYR-LQYKERQL---QYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEE 954
+R ++ R+L Q L+ H E K R SL + VE + EE
Sbjct: 615 CHRKMEVTGRELSSCQLLISQH-----EAKIR----------SLTEYMQSVELKKRHLEE 659
Query: 955 QLAQYQANANQLQKLQATFEFTANIARQEEKVRKKE----KEILESREKQQREALERALA 1010
Y + +++L KLQA E +A ++++ ++ K+ LE + + REA R LA
Sbjct: 660 ---SYDSLSDELAKLQAQ-ETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLA 715
Query: 1011 RLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYE 1070
RL EI E+++ + L L L+ E E L+ D E+L+ E
Sbjct: 716 RLRD-------------EINEKQKTIDELKD-------LNQKLQLELEKLQADYEKLKSE 755
Query: 1071 IQQLKQKIYEVDGVQKDH 1088
+ K+ E+ + + H
Sbjct: 756 EHEKSTKLQELTFLYERH 773
Score = 35.0 bits (79), Expect = 0.47
Identities = 39/170 (22%), Positives = 71/170 (41%), Gaps = 28/170 (16%)
Query: 556 EAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKL 615
E K E KS L + +S+++L + E EL+ L + RKL
Sbjct: 750 EKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGL---------EETVARELQTLHNLRKL 800
Query: 616 --------IEEMEEKQKSDKAELERMQQEV---ETQRKETEIVQLQIRKQEESLKRRSFH 664
+++ E + D + +Q++ E ++ V Q+ + L+
Sbjct: 801 FVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK 860
Query: 665 IENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKE 714
+E +L+ AE+ K E L+E +E ++ KR R Q+E+ R+KE
Sbjct: 861 LEKRLR-ATAERVKALEGALKEAKEGAMKDKR-------RYQQEVDRIKE 902
>gi|122937289 kinesin family member 18B [Homo sapiens]
Length = 855
Score = 249 bits (635), Expect = 2e-65
Identities = 158/402 (39%), Positives = 230/402 (57%), Gaps = 36/402 (8%)
Query: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGG--------TGDSGRERT 53
++++V VRVRP RE D + + ++Q+ + + N + P+GG T D +++
Sbjct: 6 STLQVVVRVRPPTPRELDSQRRPVVQVVDERVLVFNPEEPDGGFPGLKWGGTHDGPKKKG 65
Query: 54 KTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMM 113
K T+ F D + +Q+ VF+ V+ S +GYN VFAYG TG+GK++TM+
Sbjct: 66 KDLTFVF-----DRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTML 120
Query: 114 GNSGDSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLR 173
G GD G++ L+ R+ R E F +SY E+YNE++ DLL K L
Sbjct: 121 GREGDPGIMYLTTVELYRRLE--ARQQEKHFEVLISYQEVYNEQIHDLLEPKGP----LA 174
Query: 174 VREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQ 233
+RE P +G V+ LS H + + E++ GN NRT T N SSRSHAIF I Q
Sbjct: 175 IREDPDKGVVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQ 234
Query: 234 A-KFDSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADL 292
+ V+K+ L+DLAGSERA +T A G RL+EG NIN+SL+ L NV++ALAD
Sbjct: 235 QDRVPGLTQAVQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALAD- 293
Query: 293 SQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYA 352
AK ++ VPYRDS LT LLKDSLGGN +T+MIA ISP+ + Y +T +TL+YA
Sbjct: 294 --------AKGRKTHVPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYA 345
Query: 353 NRAKNI---INKPTINEDANVK----LIRELRAEIARLKTLL 387
+RAK I + + D ++ + ++L+AE+A L+ L
Sbjct: 346 DRAKEIRLSLKSNVTSLDCHISQYATICQQLQAEVAALRKKL 387
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,905,816
Number of Sequences: 37866
Number of extensions: 2201921
Number of successful extensions: 45739
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 754
Number of HSP's successfully gapped in prelim test: 1446
Number of HSP's that attempted gapping in prelim test: 10831
Number of HSP's gapped (non-prelim): 12474
length of query: 1317
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1203
effective length of database: 13,930,794
effective search space: 16758745182
effective search space used: 16758745182
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.