Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 41281571
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41281571 synovial sarcoma, X breakpoint 2 interacting
protein [Homo sapiens]
(614 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein... 1225 0.0
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 66 8e-11
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 64 3e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 64 4e-10
gi|33946313 ninein isoform 4 [Homo sapiens] 64 5e-10
gi|33946321 ninein isoform 5 [Homo sapiens] 64 5e-10
gi|148536871 ninein isoform 1 [Homo sapiens] 64 5e-10
gi|148536869 ninein isoform 2 [Homo sapiens] 64 5e-10
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 62 1e-09
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 62 2e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 62 2e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 62 2e-09
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 61 3e-09
gi|71061468 centromere protein E [Homo sapiens] 60 5e-09
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 60 6e-09
gi|55770834 centromere protein F [Homo sapiens] 59 1e-08
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 59 1e-08
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 59 1e-08
gi|148746195 trichohyalin [Homo sapiens] 59 2e-08
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 58 3e-08
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 57 4e-08
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 57 4e-08
gi|42794779 myosin 18A isoform b [Homo sapiens] 57 5e-08
gi|28416946 myosin 18A isoform a [Homo sapiens] 57 5e-08
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 57 7e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 57 7e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 57 7e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 57 7e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 57 7e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 56 9e-08
>gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein
[Homo sapiens]
Length = 614
Score = 1225 bits (3169), Expect = 0.0
Identities = 614/614 (100%), Positives = 614/614 (100%)
Query: 1 MGDWMTVTDPGLSSESKTISQYTSETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTED 60
MGDWMTVTDPGLSSESKTISQYTSETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTED
Sbjct: 1 MGDWMTVTDPGLSSESKTISQYTSETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTED 60
Query: 61 NIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENV 120
NIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENV
Sbjct: 61 NIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENV 120
Query: 121 ETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEV 180
ETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEV
Sbjct: 121 ETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEV 180
Query: 181 QKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRG 240
QKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRG
Sbjct: 181 QKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRG 240
Query: 241 SWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPR 300
SWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPR
Sbjct: 241 SWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPR 300
Query: 301 ERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQV 360
ERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQV
Sbjct: 301 ERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQV 360
Query: 361 SKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLL 420
SKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLL
Sbjct: 361 SKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLL 420
Query: 421 RDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFL 480
RDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFL
Sbjct: 421 RDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFL 480
Query: 481 NMTTFDHQNSENVKLFSAFSGSSDWDNLIVHSRQPQKKPHSVSNGSPVCMSKLTKSLPAS 540
NMTTFDHQNSENVKLFSAFSGSSDWDNLIVHSRQPQKKPHSVSNGSPVCMSKLTKSLPAS
Sbjct: 481 NMTTFDHQNSENVKLFSAFSGSSDWDNLIVHSRQPQKKPHSVSNGSPVCMSKLTKSLPAS 540
Query: 541 PSTSDFCQTRSCISEHSSINVLNITAEEIKPNQVGGERTNQKWSVASRPGSQEGCYSGCS 600
PSTSDFCQTRSCISEHSSINVLNITAEEIKPNQVGGERTNQKWSVASRPGSQEGCYSGCS
Sbjct: 541 PSTSDFCQTRSCISEHSSINVLNITAEEIKPNQVGGERTNQKWSVASRPGSQEGCYSGCS 600
Query: 601 LSYTNSHVEKDDLP 614
LSYTNSHVEKDDLP
Sbjct: 601 LSYTNSHVEKDDLP 614
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 66.2 bits (160), Expect = 8e-11
Identities = 83/399 (20%), Positives = 167/399 (41%), Gaps = 63/399 (15%)
Query: 88 KETKRELNIVAVL------NCMNELLVLQRKNLLAQEN-VETQNLKLGSDMDHLQSCYSK 140
KE KR+L L N + E + Q + L QE + Q K+ + L+ K
Sbjct: 211 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 270
Query: 141 LKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKR 200
++EQ E RR+ L+E++++L+ + + L + K + E Q + + + M+
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQ--EEKMWEQEEKMRE 328
Query: 201 KEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILL 260
+E + + +ERL + +++ E + D+ ++
Sbjct: 329 QEEKMWRQEERLWEQEKQMREQ-------------------------EQKMRDQEERMWE 363
Query: 261 NDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGE 320
D R+K+ M E K Q+ K + + ++KK RE + +E+ +
Sbjct: 364 QDERLREKEERMREQE-KMWEQEEKMQEEERIREREKKMREEEETMR------EQEEKMQ 416
Query: 321 LSRESMWDL-SCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDH 379
E+MW+ E +++L K W EK+ Q K+ + E+ I Q+
Sbjct: 417 KQEENMWEQEEKEWQQQRLPEQKEKLW-----EQEKMQEQEEKI----WEQEEKIRDQEE 467
Query: 380 EQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLF 439
EK +E ++ Q+ + +Q D + ++ + E+ ERL+E+
Sbjct: 468 MWGQEKKMWR----QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM 523
Query: 440 KEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQ 478
+EQKK +++E ++ E+K E+E+ +W +++
Sbjct: 524 REQKKMWQQEE--------KMREEKKTQEQEKKTWDQEE 554
Score = 54.3 bits (129), Expect = 3e-07
Identities = 82/398 (20%), Positives = 176/398 (44%), Gaps = 43/398 (10%)
Query: 105 ELLVLQRKNLLAQEN-VETQNLKLGSDMDHLQSCYSKLKEQLET-SRREMIGLQERDRQL 162
E L Q K + QE + Q ++ + L+ +++EQ + + E + +ER R+
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 163 QCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQL----VMN 218
+ K R + ++ +++++QK + + + + KE + +L E+ +L M
Sbjct: 398 EKKMREEEETMREQEEKMQKQEENM--------WEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Query: 219 KKDKKI---AMDILNYVGRADGKRGSWRTGKTEARNEDEMYKI--LLNDYEYR---QKQI 270
++++KI I + ++ WR K + ED+M++ + D E + Q++
Sbjct: 450 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ-EDQMWEQEEKMRDQEQKMWDQEER 508
Query: 271 LMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGE----LSRESM 326
+ E E + ++ +E + ++K E+ D EE E RE
Sbjct: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
Query: 327 WDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKL 386
E +REQ +++Q ++ EK+ Q K+ E+ + Q+ + ++
Sbjct: 569 MREEEEMMREQ-EEKMQEQEEKMREQEEKMWEQEEKMQ----EQEEKMWEQEEKMWEQEE 623
Query: 387 ELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNF 446
E ++Q+ +EM+ Q++ +Q+Q ++ + +R+ EEK R +EE +E+K
Sbjct: 624 EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK--MRE---QEEKMREQEEKMQGQEEKMRE 678
Query: 447 ERERRSFTEAAIR------LGLERKAFEEERASWLKQQ 478
+ E+ E +R G E K + +E W +++
Sbjct: 679 QEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEE 716
Score = 52.8 bits (125), Expect = 9e-07
Identities = 69/370 (18%), Positives = 161/370 (43%), Gaps = 42/370 (11%)
Query: 110 QRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNL 169
Q K L QE + KL + +Q K+ EQ E R E++ ++ + L
Sbjct: 288 QEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR-------EQEEKMWRQEERL 340
Query: 170 HQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDIL 229
+ K +++ QK+++ R + + ++ KE + ++ Q +++++I
Sbjct: 341 WEQEKQMREQEQKMRD-QEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI----- 394
Query: 230 NYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMI 289
R + + R E+E + + +Q++ + E E + Q++ ++
Sbjct: 395 -------------REREKKMREEEETMR-EQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
Query: 290 SLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRIL 349
L +K + +E I D EE G+ + MW E +REQ + + +Q +
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ--EKKMW--RQEKMREQ-EDQMWEQEEKM 495
Query: 350 KSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLA 409
+ +K+ +Q ++ + DE + +++ +E +K+ + ++ +E KTQ+Q +
Sbjct: 496 RDQEQKMWDQEERMWEQ---DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW-- 550
Query: 410 TAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRL-GLERKAFE 468
D + + + E +++++EE + +EQ++ + + E ++ E K E
Sbjct: 551 ----DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQE 606
Query: 469 EERASWLKQQ 478
+E W +++
Sbjct: 607 QEEKMWEQEE 616
Score = 44.7 bits (104), Expect = 3e-04
Identities = 65/343 (18%), Positives = 142/343 (41%), Gaps = 26/343 (7%)
Query: 146 ETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQN-------IIASRATQYNHDM 198
E RRE+ R L C+ L L +D +K ++ +A R H
Sbjct: 81 EALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFA 140
Query: 199 KRKERE------YNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNE 252
+R ++K +R + + ++D N + + K+ + + E
Sbjct: 141 GELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAE 200
Query: 253 DEMYKILLNDYEYRQK----QILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTG 308
E +I LN E ++K + L+ + + ++M ++ L +KK ++ ++
Sbjct: 201 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMW 258
Query: 309 TVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGF 368
+ E G++ + E +R Q +R+Q + L+ ++L Q E
Sbjct: 259 RQEERLREQEGKMREQE------EKMRRQ-EKRLREQEKELREQEKELREQKKLREQEEQ 311
Query: 369 NDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEE 428
E + E++ + E ++ + +E + Q++ +++Q D + +D L E+
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 371
Query: 429 KERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEER 471
+ER++E+ ++++++K E ER E +R E +EE+
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK 414
Score = 38.5 bits (88), Expect = 0.018
Identities = 24/101 (23%), Positives = 52/101 (51%)
Query: 380 EQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLF 439
E+E + E +I++ +E + Q++ L++Q + + ++ L E+++ L+E+
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Query: 440 KEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFL 480
+EQKK E+E + + E K E+E W +++ L
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
Score = 36.6 bits (83), Expect = 0.070
Identities = 27/154 (17%), Positives = 73/154 (47%), Gaps = 4/154 (2%)
Query: 329 LSCETVREQLTNS-IRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDH---EQETE 384
LS E R +TN ++K+ L+ + +++ S++ L + + R + +T
Sbjct: 171 LSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTN 230
Query: 385 KLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKK 444
L+ E+ + +E ++ Q++ +++Q + + ++ + E++E+++ + +EQ+K
Sbjct: 231 TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK 290
Query: 445 NFERERRSFTEAAIRLGLERKAFEEERASWLKQQ 478
+ + E E + E+E W +++
Sbjct: 291 ELREQEKELREQKKLREQEEQMQEQEEKMWEQEE 324
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 64.3 bits (155), Expect = 3e-10
Identities = 82/416 (19%), Positives = 182/416 (43%), Gaps = 44/416 (10%)
Query: 88 KETKRELNIVAVL------NCMNELLVLQRKNLLAQEN-VETQNLKLGSDMDHLQSCYSK 140
KE KR+L L N + E + Q + L QE + Q K+ + L+ K
Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 308
Query: 141 LKEQLETSRREMIGLQERDRQLQCKNRNLHQL--LKNEKDEVQKLQNIIASRATQYNHDM 198
++EQ E R+ L+E++++L+ + + L + L+ +++++Q+ + + + M
Sbjct: 309 MREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEE----KMWEQEEKM 364
Query: 199 KRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEM--Y 256
+ +E + + +ERL + ++++ M D + W + E+ M
Sbjct: 365 REQEEKMWRQEERLWEQEKQMREQEQKM--------RDQEERMWEQDERLREKEERMREQ 416
Query: 257 KILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEE 316
+ + E +++ M+ E K Q+ K + + ++KK RE + +E
Sbjct: 417 EKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE------QE 470
Query: 317 DAGELSRESMWDLS-CETVREQLTNSIRKQWRI--LKSHVEKLDNQVSKVH--LEGFNDE 371
+ + E+MW+ E +++L K W ++ EK+ Q K+ E + E
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530
Query: 372 DVISRQD--HEQET------EKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDC 423
+ RQ+ EQE EK+ + Q+ + + ++ Q+Q +D + + +
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE-KMREEE 589
Query: 424 YLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLG-LERKAFEEERASWLKQQ 478
+ E +++++EE + +EQ++ + + E ++ E K E+E W +++
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Score = 58.5 bits (140), Expect = 2e-08
Identities = 68/394 (17%), Positives = 179/394 (45%), Gaps = 34/394 (8%)
Query: 110 QRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNL 169
Q K L Q+ + Q ++ + + K++EQ E R+ L E+++Q+ R
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM----REQ 388
Query: 170 HQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIA--MD 227
Q ++++++ + + R + M+ +E+ + ++++ + M +++KK +
Sbjct: 389 EQKMRDQEERMWEQDE----RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Query: 228 ILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKE 287
+ R + R + R ++E + +Q++ + E E + Q++ ++
Sbjct: 445 KMQEEERIREREKKMREEEETMREQEEKMQ--------KQEENMWEQEEKEWQQQRLPEQ 496
Query: 288 MISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQ------LTNS 341
L +K + +E I D EE G+ + MW E +REQ
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ--EKKMWRQ--EKMREQEDQMWEQEEK 552
Query: 342 IRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQ 401
+R Q + + E+++ + + + ++ E+ + ++ +E EK ++++ +EM++ Q+
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK---KMREEEEMMREQE 609
Query: 402 QLLQQQLATAYDDDTTSLLRDCYLLEEKERL-KEEWSLFKEQKKNFERERRSFTEAAIRL 460
+ +Q+Q + + ++ + E++E++ ++E ++++++K +E++R E +L
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR--LPEQKEKL 667
Query: 461 GLERKAFEEERASWLKQQFLNMTTFDHQNSENVK 494
K E+E+ +++ + + E K
Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701
Score = 55.8 bits (133), Expect = 1e-07
Identities = 74/360 (20%), Positives = 156/360 (43%), Gaps = 42/360 (11%)
Query: 140 KLKEQLETSR--REMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHD 197
K++EQ + +R E + +ER R+ + K R + ++ +++++QK + + +
Sbjct: 431 KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM--------WE 482
Query: 198 MKRKEREYNKLKERLHQL----VMNKKDKKI---AMDILNYVGRADGKRGSWRTGKTEAR 250
+ KE + +L E+ +L M ++++KI I + ++ WR K +
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 251 NEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKK---EMISLLSPQKKKPRERVDDST 307
ED+M++ + QK E KK +Q KK + + ++ + RE+
Sbjct: 543 -EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 308 GTVISDVEEDAGELSR------ESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVS 361
++ + EE E E MW+ E++ K W EK+ Q
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQE-----EKMQEQEEKMWE----QEEKMWEQEE 652
Query: 362 KVHLEGFNDEDVISRQDHE--QETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSL 419
K+ + E +HE QE EK++ + ++ E K +++ +Q+ T D +
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW---DQEKM 709
Query: 420 LRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRL-GLERKAFEEERASWLKQQ 478
+ + E +++++EE + +EQ++ + + E + E K +E+E W +Q+
Sbjct: 710 REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769
Score = 50.8 bits (120), Expect = 4e-06
Identities = 59/321 (18%), Positives = 147/321 (45%), Gaps = 37/321 (11%)
Query: 165 KNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKI 224
+N ++ LK + E+Q+ + S ++ ++K +R+ + K L Q+ N +++
Sbjct: 215 RNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM 274
Query: 225 AMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQM 284
+ R + + R ++E K+ + R+++ M E K Q+
Sbjct: 275 WR-----------QEEELREQEKKIRKQEE--KMWRQEERLREQEGKMREQEEKMWRQEK 321
Query: 285 K-KEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIR 343
+ +E L Q+K+ RE+ + + + EE E E MW+ E +REQ R
Sbjct: 322 RLREQEKELREQEKELREQKE------LREQEEQMQE-QEEKMWEQE-EKMREQEEKMWR 373
Query: 344 KQWRI------LKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMI 397
++ R+ ++ +K+ +Q ++ + DE + +++ +E EK+ ++++ +E
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQ---DERLREKEERMREQEKMWEQVEKMREEK 430
Query: 398 KTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAA 457
K Q+Q + + D + + + E +++++EE +EQ++ +++ + E
Sbjct: 431 KMQEQEKKTR------DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 458 IRLGLERKAFEEERASWLKQQ 478
+ +++ E++ W +++
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEK 505
Score = 50.4 bits (119), Expect = 5e-06
Identities = 92/420 (21%), Positives = 172/420 (40%), Gaps = 52/420 (12%)
Query: 84 ESKGKETK-RELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLK 142
E+K K T R+ NI V + ++K + N ET + Q ++LK
Sbjct: 24 EAKKKFTDYRQWNIAGVGTGATDT---KKKKINHGTNPETTTSGGCHSPEDTQQNRAQLK 80
Query: 143 EQLETS-------RREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYN 195
E+ + S RRE+ R L C+ L L +D +K ++ + +N
Sbjct: 81 EEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGTPSSFN 140
Query: 196 HDMKRKER--------------EYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGS 241
+ + R E L RLH + + A+ ++ + +
Sbjct: 141 LALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIE 200
Query: 242 WRTGKTEARNEDEMYKILLNDYEYRQKQILMENAEL--KKVLQQMKKEMISLLSPQKKKP 299
T + +A + E+Y+ + + E ++K NAEL K L + +K I L + K+
Sbjct: 201 ELTKERDALSL-ELYRNTITNEELKKK-----NAELQEKLPLAESEKSEIQLNVKELKRK 254
Query: 300 RERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQ 359
ER ++ V+ + +E MW E +REQ IRKQ + E+L Q
Sbjct: 255 LERAK----FLLPQVQTNT---LQEEMWRQE-EELREQ-EKKIRKQEEKMWRQEERLREQ 305
Query: 360 VSKVHLEGFNDEDVISRQD-----HEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDD 414
K+ E+ + RQ+ E+E + E E+++ KE+ + Q++ +Q+Q ++
Sbjct: 306 EGKMR----EQEEKMWRQEKRLREQEKELREQEKELREQKEL-REQEEQMQEQEEKMWEQ 360
Query: 415 DTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASW 474
+ ++ + ++ERL E+ +EQ++ + E RL + + E+ W
Sbjct: 361 EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMW 420
Score = 49.3 bits (116), Expect = 1e-05
Identities = 87/440 (19%), Positives = 186/440 (42%), Gaps = 54/440 (12%)
Query: 63 EQSISYLDQELTTFGFPSLYEESKGKETKRELNIVA-VLNCMNELLVLQRKNLLAQENVE 121
EQ DQE + EE + +E ++++ + E + Q +N+ QE E
Sbjct: 434 EQEKKTRDQE------EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Query: 122 TQNLKLGS------DMDHLQSCYSKLKEQLETSR--REMIGLQERDRQLQCKNRNLHQLL 173
Q +L + + +Q K+ EQ E R EM G +++ + + Q+
Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547
Query: 174 KNE---KDEVQKL--QNIIASRATQYNH----DMKRKEREYNKLKERLHQL-----VMNK 219
+ E +D+ QK+ Q + TQ D + K RE +++ER ++ +M +
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607
Query: 220 KDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKK 279
+++K+ + + W + E++M++ Q++ + E E
Sbjct: 608 QEEKMQEQEEKM---QEQEEKMWEQEEKMQEQEEKMWE---------QEEKMWEQEEKMW 655
Query: 280 VLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVE-EDAGELSRESMWDLSCETVREQL 338
Q++ ++ L +K + +E++ + + + E + + WD E +RE+
Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ--EKMREE- 712
Query: 339 TNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIK 398
S+R++ + ++ E + Q K+ E Q+ E+E + E ++ + +E +
Sbjct: 713 -ESMREREKKMREEEEMMREQEEKMQ------EQEEKMQEQEEEMWEQEEKMWEQEEKMW 765
Query: 399 TQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAI 458
QQ+L +Q+ ++ + + EEK R +EE +E+K + E+ E +
Sbjct: 766 EQQRLPEQK-EKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824
Query: 459 RLGLERKAFEEERASWLKQQ 478
G E K + +E W +++
Sbjct: 825 -WGQEEKMWGQEEKMWGQEE 843
Score = 48.1 bits (113), Expect = 2e-05
Identities = 59/359 (16%), Positives = 162/359 (45%), Gaps = 22/359 (6%)
Query: 110 QRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQL--QCKNR 167
+ K + QE + + + ++ K++E+ ET R + +Q+++ + Q +
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Query: 168 NLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKERE--YNKLKERLHQLVMNKKDKKIA 225
Q L +K+++ + + + + + K +++E + + K+ Q M +++ ++
Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547
Query: 226 MDILNYVGRADGKRGSW-RTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQM 284
D ++ W + + E + +++ K + + R+++ + E + + ++M
Sbjct: 548 EQEEKM---RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 604
Query: 285 KKEMISLLSPQKKKPRERVDD--STGTVISDVEEDAGELSRESMWDLSCETVREQ-LTNS 341
+E + Q++K +E+ + + + EE E E MW+ + +Q L
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE-QEEKMWEQEEKMWEQQRLPEQ 663
Query: 342 IRKQWRILK-SHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKL---------ELEIQ 391
K W K EK+ Q K+ + ++ ++ + EK+ E +++
Sbjct: 664 KEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Query: 392 QCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERER 450
+ +EM++ Q++ +Q+Q + + ++ + E++E++ E+ L ++++K +E E+
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 782
Score = 37.0 bits (84), Expect = 0.053
Identities = 23/101 (22%), Positives = 52/101 (51%)
Query: 380 EQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLF 439
E+E + E +I++ +E + Q++ L++Q + + ++ L E+++ L+E+
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Query: 440 KEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFL 480
+EQK+ E+E + + E K E+E W +++ L
Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 378
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 63.9 bits (154), Expect = 4e-10
Identities = 73/370 (19%), Positives = 171/370 (46%), Gaps = 29/370 (7%)
Query: 117 QENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQC----------KN 166
+E ++ K+ + ++ K++EQ E RR+ + E++ +++ K
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 167 RNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQ--LVMNKKDKKI 224
R L +++ +++++++L+ + + + KR+E E + +E+ + M ++++KI
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425
Query: 225 AMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELK-KVLQQ 283
+ ++ WR + E +E E + + E RQ+Q M E K + ++
Sbjct: 426 REQEEKI---REQEKKMWR--QEEKIHEQEK----IREEEKRQEQEEMWRQEEKIREQEE 476
Query: 284 MKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIR 343
+ ++ + +K + +E + D EE E E MW E +REQ IR
Sbjct: 477 IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE-QEEKMWRQE-EKIREQ-EEKIR 533
Query: 344 KQWRILKSHVEKLDNQVSKV--HLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQ 401
+Q ++ E + Q K+ E +++ + RQ E++ + E +I++ KE I+ Q+
Sbjct: 534 EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ--EEKIREQEEKIREQKEKIREQE 591
Query: 402 QLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLG 461
+ + +Q + + ++ + E++E++ E+ +EQ++ R+ E +RL
Sbjct: 592 EKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 651
Query: 462 LERKAFEEER 471
+ + +E +
Sbjct: 652 QQEEKMQEHQ 661
Score = 55.5 bits (132), Expect = 1e-07
Identities = 84/433 (19%), Positives = 189/433 (43%), Gaps = 74/433 (17%)
Query: 83 EESKGKETK--RELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHL----QS 136
EE K K K +L +V +L V + K L + + +L ++ DHL QS
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 137 CYSKLKEQLETSR--------------REMIGLQERDRQLQCKNRNLHQLLKNEKDEVQK 182
+KL+ Q+E + R+ +QE + ++Q + + + + +++ +K
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 183 LQNIIASRATQYNHDMKRKEREYNKLKERLHQL--VMNKKDKKIA-----MDILNYVGRA 235
++ + M+R+E + +E++ +L +M +K++KI M +
Sbjct: 337 MRRQ-EEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
Query: 236 DGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQ 295
+ KR + + + +++ K+ +RQ++ + E E K+ +Q KK + Q
Sbjct: 396 EEKRQEEEKIREQEKRQEQEAKM------WRQEEKIREQEE--KIREQEKK-----MWRQ 442
Query: 296 KKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQ-----LTNSIRKQWRILK 350
++K E+ + E+ +E MW E +REQ + +Q +I K
Sbjct: 443 EEKIHEQ---------EKIREEEKRQEQEEMWRQE-EKIREQEEIWRQKEKMHEQEKIRK 492
Query: 351 SHVEKLDNQVSKVHLEGFNDEDVISRQDH-----EQETEKLELEIQQCKEMIKTQQQLLQ 405
EK+ Q K+H + E+ I Q+ E++ + E +I++ +E I+ Q++++Q
Sbjct: 493 QE-EKVWRQEEKMH----DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQ 547
Query: 406 QQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERK 465
+Q + + ++E+E+++ + +EQ++ ++ E ++ + +
Sbjct: 548 EQEEKMGEQEEK--------MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Query: 466 AFEEERASWLKQQ 478
E+ +Q+
Sbjct: 600 KIREQEEMMQEQE 612
Score = 43.9 bits (102), Expect = 4e-04
Identities = 71/365 (19%), Positives = 157/365 (43%), Gaps = 47/365 (12%)
Query: 137 CYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYN- 195
C+S EQ + + + +E + Q+ + ++L +K E+Q A Y+
Sbjct: 104 CHSPEDEQKASHQHQEALRRELEAQV-----HTIRILTCQKTELQM--------ALYYSQ 150
Query: 196 HDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNED-- 253
H +K+ E E L RLH + + A+ + A K+ + R + + D
Sbjct: 151 HAVKQLEGEARDLISRLHDSWKFAGELEQALSAV-----ATQKKKADRYIEELTKERDAL 205
Query: 254 --EMYKILLNDYEYRQKQILM---------ENAELKKVLQQMKK--EMISLLSPQKKKPR 300
E+Y+ + D E ++K + E +E++ ++++K+ E LL PQ++
Sbjct: 206 SLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA 265
Query: 301 ERVDDSTGTVISDVEEDA-GELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQ 359
E D G + V ++ +W+ + +Q + +Q ++ EK+ Q
Sbjct: 266 EA--DHLGKELQSVSAKLQAQVEENELWN----RLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 360 VSKVHL--EGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQ-QQLATAYDDDT 416
K+ E +++ R+ E EK E +Q + M + ++++ + +++ ++
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379
Query: 417 TSL---LRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERAS 473
L + + + E+E ++E +EQ+K E+E + + + E K E+E+
Sbjct: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 439
Query: 474 WLKQQ 478
W +++
Sbjct: 440 WRQEE 444
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 63.5 bits (153), Expect = 5e-10
Identities = 102/433 (23%), Positives = 182/433 (42%), Gaps = 68/433 (15%)
Query: 90 TKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLET-- 147
TK ++ A+ + E+ R L + V + KL SD+D + S + +++
Sbjct: 359 TKNSIHQAALASFKAEI----RHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHH 414
Query: 148 ---SRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQK--------LQNIIASRATQYNH 196
RR L++ D + + + L L+ E++++ + L+ I T+ N+
Sbjct: 415 AAIERRNEYNLRKLDEEYKERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEENY 474
Query: 197 -------DMKRKEREYNKLKERLHQLVMNKK-DKKIAMDILNYVGRADGKRGSWRTGKTE 248
+K R N+L E +L + K+ ++ N + K G E
Sbjct: 475 IRDRLALSLKENSRLENELLENAEKLAEYENLTNKLQRNLENVLAE---KFGDLDPSSAE 531
Query: 249 ARNEDEMYKILLNDYEYRQKQILMENA-ELKKVLQQMKKEMISLLSPQKKKPRERVDDST 307
++E + N+YE RQ ++L + EL+ L++ + + L P K P E V+ ++
Sbjct: 532 FFLQEERLTQMRNEYE-RQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANS 590
Query: 308 GTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKV-HLE 366
G + + + E + +M + E V EQ+ + L+ +E KV H E
Sbjct: 591 GGIEPEHGLGSEECNPLNM-SIEAELVIEQMKEQHHRDICCLRLELE------DKVRHYE 643
Query: 367 GFNDEDVIS--------RQDHEQETEKLELEIQQCKEMI---KTQQQLLQQ--QLATAYD 413
DE V+S +Q HE ET LE +I K I + Q +L++ AT
Sbjct: 644 KQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEAHHEATCRH 703
Query: 414 DDTTSLLR-----DCYLLEEKERLKEEWSL---FKEQKKNFERERRSFTEAAIRLGLERK 465
++ L+ + L+EK RL+ E L + + +FERER GL+
Sbjct: 704 EEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFERERE---------GLQSS 754
Query: 466 AFEEERASWLKQQ 478
A+ EE+ L Q+
Sbjct: 755 AWTEEKVRGLTQE 767
Score = 37.0 bits (84), Expect = 0.053
Identities = 62/334 (18%), Positives = 131/334 (39%), Gaps = 63/334 (18%)
Query: 152 MIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQY--NHDMKRKEREYNKLK 209
++G Q++ Q Q L EK ++Q+L + R T D+ + +LK
Sbjct: 1443 LLGFQDKHFQHQATIAELEL----EKTKLQELTRKLKERVTILVKQKDVLSHGEKEEELK 1498
Query: 210 ERLHQLVMNKKDKKIAMDILNYVGRADGKRGS-WRTGKTEARNEDEMYKILLNDYEYRQK 268
+H L + + + +++L Y + S R T ED + + L Q+
Sbjct: 1499 AMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGSQE 1558
Query: 269 Q-------ILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGEL 321
+ + ENA ++K+++ +KK++ L ++ E + S S +E EL
Sbjct: 1559 EMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKN--SQNQEKLQEL 1616
Query: 322 SRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQ 381
++ + ++ C+ +E +++ ++ EQ
Sbjct: 1617 NQR-LTEMLCQKEKEPGNSAL----------------------------------EEREQ 1641
Query: 382 ETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKE 441
E L+ E+++CK T L+ +L+ ++ + +E LK+E K+
Sbjct: 1642 EKFNLKEELERCKVQSSTLVSSLEAELSEV-------KIQTHIVQQENHLLKDELEKMKQ 1694
Query: 442 QKK-----NFERERRSFTEAAIRLGLERKAFEEE 470
+ +F+++ S +L E++A EE
Sbjct: 1695 LHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEE 1728
Score = 30.0 bits (66), Expect = 6.5
Identities = 65/352 (18%), Positives = 148/352 (42%), Gaps = 46/352 (13%)
Query: 109 LQRKNLLAQENVETQN-LKLGSDMDHLQSCYSKLKEQLETS---RREMIGL-QERDRQLQ 163
L+ + QE + Q+ ++L + + Q+ + + +E L++S ++ GL QE ++ Q
Sbjct: 714 LEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQ 773
Query: 164 CKNRNLHQLLKNEKDEVQK---------LQNIIASRATQYNHDMKRKEREYN----KLKE 210
+ +L + EK+E++K LQ T+ N + E ++ K+ E
Sbjct: 774 EQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTE 833
Query: 211 RLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQI 270
R + + + ++ + + ++ W K E E + LL + R+K
Sbjct: 834 RCES-ALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQECAEAQELLKETLKREKTT 892
Query: 271 LMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLS 330
+ + +++L++ KE ++ + ++++ + ++D + +V E L + + +L
Sbjct: 893 SLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLED-----LRNVSETQQSLLSDQILELK 947
Query: 331 CETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQD-----------H 379
RE +R++ +L Q++ LE E RQ+ H
Sbjct: 948 SSHKRE-----LREREEVLCQ--AGASEQLASQRLERLEMEHDQERQEMMSKLLAMENIH 1000
Query: 380 EQETEKLELE-IQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKE 430
+ E + E + E+ + Q ++ + Q AT+ + L C ++ E+E
Sbjct: 1001 KATCETADRERAEMSTEISRLQSKIKEMQQATS---PLSMLQSGCQVIGEEE 1049
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 63.5 bits (153), Expect = 5e-10
Identities = 102/433 (23%), Positives = 182/433 (42%), Gaps = 68/433 (15%)
Query: 90 TKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLET-- 147
TK ++ A+ + E+ R L + V + KL SD+D + S + +++
Sbjct: 353 TKNSIHQAALASFKAEI----RHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHH 408
Query: 148 ---SRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQK--------LQNIIASRATQYNH 196
RR L++ D + + + L L+ E++++ + L+ I T+ N+
Sbjct: 409 AAIERRNEYNLRKLDEEYKERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEENY 468
Query: 197 -------DMKRKEREYNKLKERLHQLVMNKK-DKKIAMDILNYVGRADGKRGSWRTGKTE 248
+K R N+L E +L + K+ ++ N + K G E
Sbjct: 469 IRDRLALSLKENSRLENELLENAEKLAEYENLTNKLQRNLENVLAE---KFGDLDPSSAE 525
Query: 249 ARNEDEMYKILLNDYEYRQKQILMENA-ELKKVLQQMKKEMISLLSPQKKKPRERVDDST 307
++E + N+YE RQ ++L + EL+ L++ + + L P K P E V+ ++
Sbjct: 526 FFLQEERLTQMRNEYE-RQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANS 584
Query: 308 GTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKV-HLE 366
G + + + E + +M + E V EQ+ + L+ +E KV H E
Sbjct: 585 GGIEPEHGLGSEECNPLNM-SIEAELVIEQMKEQHHRDICCLRLELE------DKVRHYE 637
Query: 367 GFNDEDVIS--------RQDHEQETEKLELEIQQCKEMI---KTQQQLLQQ--QLATAYD 413
DE V+S +Q HE ET LE +I K I + Q +L++ AT
Sbjct: 638 KQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEAHHEATCRH 697
Query: 414 DDTTSLLR-----DCYLLEEKERLKEEWSL---FKEQKKNFERERRSFTEAAIRLGLERK 465
++ L+ + L+EK RL+ E L + + +FERER GL+
Sbjct: 698 EEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFERERE---------GLQSS 748
Query: 466 AFEEERASWLKQQ 478
A+ EE+ L Q+
Sbjct: 749 AWTEEKVRGLTQE 761
Score = 37.0 bits (84), Expect = 0.053
Identities = 62/334 (18%), Positives = 131/334 (39%), Gaps = 63/334 (18%)
Query: 152 MIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQY--NHDMKRKEREYNKLK 209
++G Q++ Q Q L EK ++Q+L + R T D+ + +LK
Sbjct: 1437 LLGFQDKHFQHQATIAELEL----EKTKLQELTRKLKERVTILVKQKDVLSHGEKEEELK 1492
Query: 210 ERLHQLVMNKKDKKIAMDILNYVGRADGKRGS-WRTGKTEARNEDEMYKILLNDYEYRQK 268
+H L + + + +++L Y + S R T ED + + L Q+
Sbjct: 1493 AMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGSQE 1552
Query: 269 Q-------ILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGEL 321
+ + ENA ++K+++ +KK++ L ++ E + S S +E EL
Sbjct: 1553 EMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKN--SQNQEKLQEL 1610
Query: 322 SRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQ 381
++ + ++ C+ +E +++ ++ EQ
Sbjct: 1611 NQR-LTEMLCQKEKEPGNSAL----------------------------------EEREQ 1635
Query: 382 ETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKE 441
E L+ E+++CK T L+ +L+ ++ + +E LK+E K+
Sbjct: 1636 EKFNLKEELERCKVQSSTLVSSLEAELSEV-------KIQTHIVQQENHLLKDELEKMKQ 1688
Query: 442 QKK-----NFERERRSFTEAAIRLGLERKAFEEE 470
+ +F+++ S +L E++A EE
Sbjct: 1689 LHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEE 1722
Score = 30.0 bits (66), Expect = 6.5
Identities = 65/352 (18%), Positives = 148/352 (42%), Gaps = 46/352 (13%)
Query: 109 LQRKNLLAQENVETQN-LKLGSDMDHLQSCYSKLKEQLETS---RREMIGL-QERDRQLQ 163
L+ + QE + Q+ ++L + + Q+ + + +E L++S ++ GL QE ++ Q
Sbjct: 708 LEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQ 767
Query: 164 CKNRNLHQLLKNEKDEVQK---------LQNIIASRATQYNHDMKRKEREYN----KLKE 210
+ +L + EK+E++K LQ T+ N + E ++ K+ E
Sbjct: 768 EQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTE 827
Query: 211 RLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQI 270
R + + + ++ + + ++ W K E E + LL + R+K
Sbjct: 828 RCES-ALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQECAEAQELLKETLKREKTT 886
Query: 271 LMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLS 330
+ + +++L++ KE ++ + ++++ + ++D + +V E L + + +L
Sbjct: 887 SLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLED-----LRNVSETQQSLLSDQILELK 941
Query: 331 CETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQD-----------H 379
RE +R++ +L Q++ LE E RQ+ H
Sbjct: 942 SSHKRE-----LREREEVLCQ--AGASEQLASQRLERLEMEHDQERQEMMSKLLAMENIH 994
Query: 380 EQETEKLELE-IQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKE 430
+ E + E + E+ + Q ++ + Q AT+ + L C ++ E+E
Sbjct: 995 KATCETADRERAEMSTEISRLQSKIKEMQQATS---PLSMLQSGCQVIGEEE 1043
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 63.5 bits (153), Expect = 5e-10
Identities = 102/433 (23%), Positives = 182/433 (42%), Gaps = 68/433 (15%)
Query: 90 TKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLET-- 147
TK ++ A+ + E+ R L + V + KL SD+D + S + +++
Sbjct: 353 TKNSIHQAALASFKAEI----RHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHH 408
Query: 148 ---SRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQK--------LQNIIASRATQYNH 196
RR L++ D + + + L L+ E++++ + L+ I T+ N+
Sbjct: 409 AAIERRNEYNLRKLDEEYKERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEENY 468
Query: 197 -------DMKRKEREYNKLKERLHQLVMNKK-DKKIAMDILNYVGRADGKRGSWRTGKTE 248
+K R N+L E +L + K+ ++ N + K G E
Sbjct: 469 IRDRLALSLKENSRLENELLENAEKLAEYENLTNKLQRNLENVLAE---KFGDLDPSSAE 525
Query: 249 ARNEDEMYKILLNDYEYRQKQILMENA-ELKKVLQQMKKEMISLLSPQKKKPRERVDDST 307
++E + N+YE RQ ++L + EL+ L++ + + L P K P E V+ ++
Sbjct: 526 FFLQEERLTQMRNEYE-RQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANS 584
Query: 308 GTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKV-HLE 366
G + + + E + +M + E V EQ+ + L+ +E KV H E
Sbjct: 585 GGIEPEHGLGSEECNPLNM-SIEAELVIEQMKEQHHRDICCLRLELE------DKVRHYE 637
Query: 367 GFNDEDVIS--------RQDHEQETEKLELEIQQCKEMI---KTQQQLLQQ--QLATAYD 413
DE V+S +Q HE ET LE +I K I + Q +L++ AT
Sbjct: 638 KQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEAHHEATCRH 697
Query: 414 DDTTSLLR-----DCYLLEEKERLKEEWSL---FKEQKKNFERERRSFTEAAIRLGLERK 465
++ L+ + L+EK RL+ E L + + +FERER GL+
Sbjct: 698 EEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFERERE---------GLQSS 748
Query: 466 AFEEERASWLKQQ 478
A+ EE+ L Q+
Sbjct: 749 AWTEEKVRGLTQE 761
Score = 37.0 bits (84), Expect = 0.053
Identities = 62/334 (18%), Positives = 131/334 (39%), Gaps = 63/334 (18%)
Query: 152 MIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQY--NHDMKRKEREYNKLK 209
++G Q++ Q Q L EK ++Q+L + R T D+ + +LK
Sbjct: 1437 LLGFQDKHFQHQATIAELEL----EKTKLQELTRKLKERVTILVKQKDVLSHGEKEEELK 1492
Query: 210 ERLHQLVMNKKDKKIAMDILNYVGRADGKRGS-WRTGKTEARNEDEMYKILLNDYEYRQK 268
+H L + + + +++L Y + S R T ED + + L Q+
Sbjct: 1493 AMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGSQE 1552
Query: 269 Q-------ILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGEL 321
+ + ENA ++K+++ +KK++ L ++ E + S S +E EL
Sbjct: 1553 EMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKN--SQNQEKLQEL 1610
Query: 322 SRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQ 381
++ + ++ C+ +E +++ ++ EQ
Sbjct: 1611 NQR-LTEMLCQKEKEPGNSAL----------------------------------EEREQ 1635
Query: 382 ETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKE 441
E L+ E+++CK T L+ +L+ ++ + +E LK+E K+
Sbjct: 1636 EKFNLKEELERCKVQSSTLVSSLEAELSEV-------KIQTHIVQQENHLLKDELEKMKQ 1688
Query: 442 QKK-----NFERERRSFTEAAIRLGLERKAFEEE 470
+ +F+++ S +L E++A EE
Sbjct: 1689 LHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEE 1722
Score = 30.0 bits (66), Expect = 6.5
Identities = 65/352 (18%), Positives = 148/352 (42%), Gaps = 46/352 (13%)
Query: 109 LQRKNLLAQENVETQN-LKLGSDMDHLQSCYSKLKEQLETS---RREMIGL-QERDRQLQ 163
L+ + QE + Q+ ++L + + Q+ + + +E L++S ++ GL QE ++ Q
Sbjct: 708 LEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQ 767
Query: 164 CKNRNLHQLLKNEKDEVQK---------LQNIIASRATQYNHDMKRKEREYN----KLKE 210
+ +L + EK+E++K LQ T+ N + E ++ K+ E
Sbjct: 768 EQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTE 827
Query: 211 RLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQI 270
R + + + ++ + + ++ W K E E + LL + R+K
Sbjct: 828 RCES-ALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQECAEAQELLKETLKREKTT 886
Query: 271 LMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLS 330
+ + +++L++ KE ++ + ++++ + ++D + +V E L + + +L
Sbjct: 887 SLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLED-----LRNVSETQQSLLSDQILELK 941
Query: 331 CETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQD-----------H 379
RE +R++ +L Q++ LE E RQ+ H
Sbjct: 942 SSHKRE-----LREREEVLCQ--AGASEQLASQRLERLEMEHDQERQEMMSKLLAMENIH 994
Query: 380 EQETEKLELE-IQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKE 430
+ E + E + E+ + Q ++ + Q AT+ + L C ++ E+E
Sbjct: 995 KATCETADRERAEMSTEISRLQSKIKEMQQATS---PLSMLQSGCQVIGEEE 1043
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 63.5 bits (153), Expect = 5e-10
Identities = 102/433 (23%), Positives = 182/433 (42%), Gaps = 68/433 (15%)
Query: 90 TKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLET-- 147
TK ++ A+ + E+ R L + V + KL SD+D + S + +++
Sbjct: 353 TKNSIHQAALASFKAEI----RHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHH 408
Query: 148 ---SRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQK--------LQNIIASRATQYNH 196
RR L++ D + + + L L+ E++++ + L+ I T+ N+
Sbjct: 409 AAIERRNEYNLRKLDEEYKERIAALKNELRKEREQILQQAGKQRLELEQEIEKAKTEENY 468
Query: 197 -------DMKRKEREYNKLKERLHQLVMNKK-DKKIAMDILNYVGRADGKRGSWRTGKTE 248
+K R N+L E +L + K+ ++ N + K G E
Sbjct: 469 IRDRLALSLKENSRLENELLENAEKLAEYENLTNKLQRNLENVLAE---KFGDLDPSSAE 525
Query: 249 ARNEDEMYKILLNDYEYRQKQILMENA-ELKKVLQQMKKEMISLLSPQKKKPRERVDDST 307
++E + N+YE RQ ++L + EL+ L++ + + L P K P E V+ ++
Sbjct: 526 FFLQEERLTQMRNEYE-RQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANS 584
Query: 308 GTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKV-HLE 366
G + + + E + +M + E V EQ+ + L+ +E KV H E
Sbjct: 585 GGIEPEHGLGSEECNPLNM-SIEAELVIEQMKEQHHRDICCLRLELE------DKVRHYE 637
Query: 367 GFNDEDVIS--------RQDHEQETEKLELEIQQCKEMI---KTQQQLLQQ--QLATAYD 413
DE V+S +Q HE ET LE +I K I + Q +L++ AT
Sbjct: 638 KQLDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEAHHEATCRH 697
Query: 414 DDTTSLLR-----DCYLLEEKERLKEEWSL---FKEQKKNFERERRSFTEAAIRLGLERK 465
++ L+ + L+EK RL+ E L + + +FERER GL+
Sbjct: 698 EEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFERERE---------GLQSS 748
Query: 466 AFEEERASWLKQQ 478
A+ EE+ L Q+
Sbjct: 749 AWTEEKVRGLTQE 761
Score = 37.0 bits (84), Expect = 0.053
Identities = 62/334 (18%), Positives = 131/334 (39%), Gaps = 63/334 (18%)
Query: 152 MIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQY--NHDMKRKEREYNKLK 209
++G Q++ Q Q L EK ++Q+L + R T D+ + +LK
Sbjct: 1437 LLGFQDKHFQHQATIAELEL----EKTKLQELTRKLKERVTILVKQKDVLSHGEKEEELK 1492
Query: 210 ERLHQLVMNKKDKKIAMDILNYVGRADGKRGS-WRTGKTEARNEDEMYKILLNDYEYRQK 268
+H L + + + +++L Y + S R T ED + + L Q+
Sbjct: 1493 AMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGSQE 1552
Query: 269 Q-------ILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGEL 321
+ + ENA ++K+++ +KK++ L ++ E + S S +E EL
Sbjct: 1553 EMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKN--SQNQEKLQEL 1610
Query: 322 SRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQ 381
++ + ++ C+ +E +++ ++ EQ
Sbjct: 1611 NQR-LTEMLCQKEKEPGNSAL----------------------------------EEREQ 1635
Query: 382 ETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKE 441
E L+ E+++CK T L+ +L+ ++ + +E LK+E K+
Sbjct: 1636 EKFNLKEELERCKVQSSTLVSSLEAELSEV-------KIQTHIVQQENHLLKDELEKMKQ 1688
Query: 442 QKK-----NFERERRSFTEAAIRLGLERKAFEEE 470
+ +F+++ S +L E++A EE
Sbjct: 1689 LHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEE 1722
Score = 30.0 bits (66), Expect = 6.5
Identities = 65/352 (18%), Positives = 148/352 (42%), Gaps = 46/352 (13%)
Query: 109 LQRKNLLAQENVETQN-LKLGSDMDHLQSCYSKLKEQLETS---RREMIGL-QERDRQLQ 163
L+ + QE + Q+ ++L + + Q+ + + +E L++S ++ GL QE ++ Q
Sbjct: 708 LEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQ 767
Query: 164 CKNRNLHQLLKNEKDEVQK---------LQNIIASRATQYNHDMKRKEREYN----KLKE 210
+ +L + EK+E++K LQ T+ N + E ++ K+ E
Sbjct: 768 EQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTE 827
Query: 211 RLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQI 270
R + + + ++ + + ++ W K E E + LL + R+K
Sbjct: 828 RCES-ALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQECAEAQELLKETLKREKTT 886
Query: 271 LMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLS 330
+ + +++L++ KE ++ + ++++ + ++D + +V E L + + +L
Sbjct: 887 SLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLED-----LRNVSETQQSLLSDQILELK 941
Query: 331 CETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQD-----------H 379
RE +R++ +L Q++ LE E RQ+ H
Sbjct: 942 SSHKRE-----LREREEVLCQ--AGASEQLASQRLERLEMEHDQERQEMMSKLLAMENIH 994
Query: 380 EQETEKLELE-IQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKE 430
+ E + E + E+ + Q ++ + Q AT+ + L C ++ E+E
Sbjct: 995 KATCETADRERAEMSTEISRLQSKIKEMQQATS---PLSMLQSGCQVIGEEE 1043
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.4 bits (150), Expect = 1e-09
Identities = 77/389 (19%), Positives = 173/389 (44%), Gaps = 22/389 (5%)
Query: 109 LQRKNLLAQENVETQNLKLGSDMDH---LQSCYSKLKEQLETSRREMIGLQERDRQLQCK 165
L+ + AQ+ E L+ DH + + KL ++ + E+ D +L+ K
Sbjct: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEK 219
Query: 166 NRNLHQ---LLKNEKDEVQKLQNIIASRA--TQYNHDMKRKEREYNKLKERLHQLVMNKK 220
N L + L+++EK E+Q + + Q ++ + E ++L + L + +
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279
Query: 221 DKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYE-----YRQKQILMENA 275
+ ++ N + + ++ WR + E++M + L E +RQ++ + E
Sbjct: 280 AQVEENELWNLLNQQQEEK-MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE 338
Query: 276 ELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAG-ELSRESMWDLSCETV 334
E + + + Q++K RE+ + E+D + E MW E +
Sbjct: 339 EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE-EKI 397
Query: 335 REQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISR-----QDHEQETEKLELE 389
REQ K WR K E+ D ++ + E + E+ I QD E++ ++E +
Sbjct: 398 REQEEKRQEKMWRQEKKMREQ-DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456
Query: 390 IQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERE 449
+Q+ +E ++ Q++ +Q+Q + + + ++ L +E++ ++E ++++++K +E+E
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE 516
Query: 450 RRSFTEAAIRLGLERKAFEEERASWLKQQ 478
+ + E K E+E W +++
Sbjct: 517 EKMQEQEEKMQRQEEKMREQEVRLWQQEE 545
Score = 43.5 bits (101), Expect = 6e-04
Identities = 71/391 (18%), Positives = 166/391 (42%), Gaps = 57/391 (14%)
Query: 58 TEDNIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLV--------L 109
T++ +++ + L ++L + K+ KR+L +L +L V L
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL 271
Query: 110 QRKNLLAQENVETQ---NLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKN 166
Q + Q VE NL + + K++EQ E + + ++E++ ++ +
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 167 RNLH---QLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKK 223
+H + ++ ++D++ + + I + + ++ R+ K++E +D+K
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE---------QDEK 382
Query: 224 IAMDILNYVGRADGKRGSWR-TGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQ 282
I + + WR K + E K+ + + R++ + E + Q
Sbjct: 383 I----------QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQ 432
Query: 283 QMK-KEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNS 341
+ K +E+ ++ Q++K RE V++ ++E ++ R+ E++
Sbjct: 433 EEKIRELEEMMQDQEEKLRE-VEEKMQEEEEKMQEQEEKIQRQ----------EEKIQEQ 481
Query: 342 IRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQ 401
K WR EKL Q K+ + E+ + RQ E++ + E ++Q+ +E ++ Q+
Sbjct: 482 EEKTWR-----QEKLLKQEEKI----WEQEEKMWRQ--EEKMWEQEEKMQEQEEKMQRQE 530
Query: 402 QLLQQQLATAYDDDTTSLLRDCYLLEEKERL 432
+ +++Q + + ++ L E +ERL
Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.0 bits (149), Expect = 2e-09
Identities = 77/389 (19%), Positives = 173/389 (44%), Gaps = 22/389 (5%)
Query: 109 LQRKNLLAQENVETQNLKLGSDMDH---LQSCYSKLKEQLETSRREMIGLQERDRQLQCK 165
L+ + AQ+ E L+ DH + + KL ++ + E+ D +L+ K
Sbjct: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEK 219
Query: 166 NRNLHQ---LLKNEKDEVQKLQNIIASRA--TQYNHDMKRKEREYNKLKERLHQLVMNKK 220
N L + L+++EK E+Q + + Q ++ + E ++L + L + +
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279
Query: 221 DKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYE-----YRQKQILMENA 275
+ ++ N + + ++ WR + E++M + L E +RQ++ + E
Sbjct: 280 AQVEENELWNLLNQQQEEK-MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE 338
Query: 276 ELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAG-ELSRESMWDLSCETV 334
E + + + Q++K RE+ + E+D + E MW E +
Sbjct: 339 EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE-EKI 397
Query: 335 REQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISR-----QDHEQETEKLELE 389
REQ K WR K E+ D ++ + E + E+ I QD E++ ++E +
Sbjct: 398 REQEEKRQEKMWRQEKKMREQ-DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456
Query: 390 IQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERE 449
+Q+ +E ++ Q++ +Q+Q + + + ++ L +E++ ++E ++++++K +E+E
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE 516
Query: 450 RRSFTEAAIRLGLERKAFEEERASWLKQQ 478
+ + E K E+E W +++
Sbjct: 517 EKMQEQEEKMQRQEEKMREQEVRLWQQEE 545
Score = 43.5 bits (101), Expect = 6e-04
Identities = 71/391 (18%), Positives = 166/391 (42%), Gaps = 57/391 (14%)
Query: 58 TEDNIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLV--------L 109
T++ +++ + L ++L + K+ KR+L +L +L V L
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL 271
Query: 110 QRKNLLAQENVETQ---NLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKN 166
Q + Q VE NL + + K++EQ E + + ++E++ ++ +
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 167 RNLH---QLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKK 223
+H + ++ ++D++ + + I + + ++ R+ K++E +D+K
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE---------QDEK 382
Query: 224 IAMDILNYVGRADGKRGSWR-TGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQ 282
I + + WR K + E K+ + + R++ + E + Q
Sbjct: 383 I----------QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQ 432
Query: 283 QMK-KEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNS 341
+ K +E+ ++ Q++K RE V++ ++E ++ R+ E++
Sbjct: 433 EEKIRELEEMMQDQEEKLRE-VEEKMQEEEEKMQEQEEKIQRQ----------EEKIQEQ 481
Query: 342 IRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQ 401
K WR EKL Q K+ + E+ + RQ E++ + E ++Q+ +E ++ Q+
Sbjct: 482 EEKTWR-----QEKLLKQEEKI----WEQEEKMWRQ--EEKMWEQEEKMQEQEEKMQRQE 530
Query: 402 QLLQQQLATAYDDDTTSLLRDCYLLEEKERL 432
+ +++Q + + ++ L E +ERL
Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 62.0 bits (149), Expect = 2e-09
Identities = 75/367 (20%), Positives = 170/367 (46%), Gaps = 44/367 (11%)
Query: 112 KNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRR--EMIGLQERDRQLQCKNRNL 169
+N + E ++ +N KL + ++S S+++ ++ +R E L +QLQ + +L
Sbjct: 199 RNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHL 258
Query: 170 HQLLKN--EKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMD 227
+ L++ K + Q +N + +R Q + ++ E K++ER ++ ++++KI
Sbjct: 259 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE--KIQEREEKI--QEQEEKI--- 311
Query: 228 ILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKE 287
R + + R ++EM + RQ++++ E E + L++ E
Sbjct: 312 ---------------REQEEKMRRQEEMMWEK-EEKMRRQEEMMWEKEEKIRELEEKMHE 355
Query: 288 MISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWR 347
+ ++K+ E E++ + MW E +REQ IR+Q
Sbjct: 356 QEKIREQEEKRQEEE---------KIREQEKRQEQEAKMWRQE-EKIREQ-EEKIREQEE 404
Query: 348 ILKSHVEKLDNQVSKV---HLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLL 404
+++ EK+ Q K+ E E+ + RQ E++ + E +I++ +E I+ Q++++
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ--EEKIREQEKKIREQEEKIREQEEMM 462
Query: 405 QQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNF-ERERRSFTEAAIRLGLE 463
Q+Q + + ++ + E++E+++ + +EQ+K E+E + + + E
Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 522
Query: 464 RKAFEEE 470
K +E+E
Sbjct: 523 EKMWEQE 529
Score = 60.1 bits (144), Expect = 6e-09
Identities = 76/411 (18%), Positives = 179/411 (43%), Gaps = 70/411 (17%)
Query: 83 EESKGKETK--RELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHL----QS 136
EE K K K +L +V +L V + K L + + +L ++ DHL QS
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 137 CYSKLKEQLETSR--------------REMIGLQERDRQLQCKNRNLHQLLKNEKDEVQK 182
+KL+ Q+E + R+ +QER+ ++Q + ++ +++++++
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQ----EQEEKIREQEEKMRR 320
Query: 183 LQNIIASRATQYNHD---MKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKR 239
+ ++ + + M KE + +L+E++H+ ++ ++ KR
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE--------------KR 366
Query: 240 GSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKP 299
+ + + +++ K+ +RQ++ + E E + ++M +E + Q++K
Sbjct: 367 QEEEKIREQEKRQEQEAKM------WRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 300 RERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQ 359
E+ ++ ++E ++ R+ E +REQ IR+Q ++ E + Q
Sbjct: 421 WEQEEE--------MQEQEEKMRRQE------EKIREQ-EKKIREQEEKIREQEEMMQEQ 465
Query: 360 VSKV-HLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTS 418
K+ EG E Q+ E++ + E E I+ Q++ +++Q + +
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQE-------EKIREQEKKIREQEEKIREQEEMM 518
Query: 419 LLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEE 469
++ + E++E++ E+ +EQ++ R+ E +RL + + +E
Sbjct: 519 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 46.6 bits (109), Expect = 7e-05
Identities = 73/348 (20%), Positives = 147/348 (42%), Gaps = 55/348 (15%)
Query: 137 CYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYN- 195
C+S EQ + + + +E + Q+Q ++L +K E+Q A Y+
Sbjct: 92 CHSPEDEQKASHQHQEALRRELEAQVQTI-----RILTCQKTELQM--------ALYYSQ 138
Query: 196 HDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNED-- 253
H +K+ E E L RLH + + A+ + A K+ + R + + D
Sbjct: 139 HAVKQLEGEARDLISRLHDSWKFAGELEQALSAV-----ATQKKKADRYIEELTKERDAL 193
Query: 254 --EMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVI 311
E+Y+ + D E ++K NA+L++ LQ ++ E + K+ R+
Sbjct: 194 SLELYRNTITDEELKEK-----NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ 248
Query: 312 SDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHL-EGFND 370
++ +A L +E L+S KL QV + L N
Sbjct: 249 QQLQAEADHLGKE------------------------LQSVSAKLQAQVEENELWNRLNQ 284
Query: 371 EDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKE 430
+ E++ ++ E +IQ+ +E I+ Q++ +++Q ++ + ++ + E++E
Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 344
Query: 431 RLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQ 478
+++E EQ+K E+E + E IR + K E+E W +++
Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIR--EQEKRQEQEAKMWRQEE 390
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 62.0 bits (149), Expect = 2e-09
Identities = 79/454 (17%), Positives = 198/454 (43%), Gaps = 52/454 (11%)
Query: 58 TEDNIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLV--------L 109
T++ +++ + L ++L + KE KR+L +L +L L
Sbjct: 276 TDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 335
Query: 110 QRKNLLAQENVETQNL----------KLGSDMDHLQSCYSKLKEQLETSRREMIGLQERD 159
Q + Q VE L K+ + +Q K++EQ E R + +E+
Sbjct: 336 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ----EEKI 391
Query: 160 RQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHD---MKRKEREYNKLKERLHQL- 215
R+ + K R +++ +++++++ + ++ + + M KE + +L+E++H+
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 451
Query: 216 -VMNKKDKKIAMD-ILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILME 273
+ +++K+ + I R + + WR + E+++ + + +RQ++ + E
Sbjct: 452 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE--QEEKMWRQEEKIHE 509
Query: 274 NAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMW--DLSC 331
+K+ ++ K++ + Q++K RE+ + +E+ E MW +
Sbjct: 510 Q---EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKM 566
Query: 332 ETVREQLTNSIRKQWRI---LKSHVEKLDNQVSKVHLE-----------GFNDEDVISRQ 377
E++ K WR ++ EK+ Q K+ + G +E + ++
Sbjct: 567 HDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 626
Query: 378 DHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWS 437
+ QE E+ ++++ +E I+ Q++ +++Q + + ++ + E++E++ E+
Sbjct: 627 EKMQEQEE---KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 683
Query: 438 LFKEQKKNFERERRSFTEAAIRLGLERKAFEEER 471
+EQ++ R+ E +RL + + +E +
Sbjct: 684 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717
Score = 45.8 bits (107), Expect = 1e-04
Identities = 71/366 (19%), Positives = 158/366 (43%), Gaps = 49/366 (13%)
Query: 137 CYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYN- 195
C+S EQ + + + +E + Q+ + ++L +K E+Q A Y+
Sbjct: 165 CHSPEDEQKASHQHQEALRRELEAQV-----HTIRILTCQKTELQM--------ALYYSQ 211
Query: 196 HDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNED-- 253
H +K+ E E L RLH + + A+ + A K+ + R + + D
Sbjct: 212 HAVKQLEGEARDLISRLHDSWKFAGELEQALSAV-----ATQKKKADRYIEELTKERDAL 266
Query: 254 --EMYKILLNDYEYRQKQILM---------ENAELKKVLQQMKK--EMISLLSPQKKKPR 300
E+Y+ + D E ++K + E +E++ ++++K+ E LL PQ++
Sbjct: 267 SLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA 326
Query: 301 ERVDDSTGTVISDVEEDA-GELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQ 359
E D G + V ++ +W+ + +Q + +Q ++ EK+ Q
Sbjct: 327 EA--DHLGKELQSVSAKLQAQVEENELWN----RLNQQQEEKMWRQEEKIQEWEEKIQEQ 380
Query: 360 VSKVHL--EGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTT 417
K+ E +++ R+ E EK E ++++ +EM+ +++ +++Q ++ +
Sbjct: 381 EEKIREQEEKIREQEEKMRRQEEMMWEKEE-KMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439
Query: 418 -----SLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERA 472
+ + + E+E ++E +EQ+K E+E + + + E K E+E
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 473 SWLKQQ 478
W +++
Sbjct: 500 MWRQEE 505
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 61.2 bits (147), Expect = 3e-09
Identities = 91/461 (19%), Positives = 196/461 (42%), Gaps = 50/461 (10%)
Query: 12 LSSESKTISQYTSETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTE-DNIEQSISYLD 70
L + +T+SQ ETK+ L ++ + +++ + V A TE ++ +S +
Sbjct: 812 LKQDFETLSQ---ETKIQHEELNNR--IQTTVTELQKVKMEKEALMTELSTVKDKLSKVS 866
Query: 71 QELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSD 130
L E KGK L++ + L +Q +N L ++ ++L+ +
Sbjct: 867 DSLKNSKSEFEKENQKGKAAI--LDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKE 924
Query: 131 MDH-LQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIAS 189
H L+ + ++EQL ++ + ++ ++QLQ L Q + +K +++ LQ +
Sbjct: 925 ASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKI 984
Query: 190 RATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEA 249
Q K NKL+++L Q +K + +L +
Sbjct: 985 AVLQ-------KTELENKLQQQLTQAAQELAAEKEKISVL----------------QNNY 1021
Query: 250 RNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKK-KPRERVDDSTG 308
E +K L +D+ R+ ++L +LK V +++ L+S + + + ++
Sbjct: 1022 EKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELK 1081
Query: 309 TVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGF 368
T + +E+D+ + +E C+ +++ I+K+ + + + ++++++
Sbjct: 1082 TAKATLEQDSAK--KEQQLQERCKALQD-----IQKEKSLKEKELVNEKSKLAEIEEIKC 1134
Query: 369 NDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEE 428
E I++ + E ++ KLE I++ + +Q L+QQ+L D+ L
Sbjct: 1135 RQEKEITKLNEELKSHKLE-SIKEITNLKDAKQLLIQQKLELQGKADS--------LKAA 1185
Query: 429 KERLKEEWSLFKEQKKNFERE-RRSFTEAAIRLGLERKAFE 468
E+ K + K+Q K E E ++ F E +L E K E
Sbjct: 1186 VEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKE 1226
Score = 52.8 bits (125), Expect = 9e-07
Identities = 106/521 (20%), Positives = 206/521 (39%), Gaps = 82/521 (15%)
Query: 13 SSESKTISQYTSETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTEDNIEQSISYLDQE 72
+S TISQ SE P Q+V L K S + +++ +Q+
Sbjct: 263 ASSEATISQLRSELAKGP-----QEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQD 317
Query: 73 LTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNL------- 125
T EE +E+ + NI A L+ +L Q ++ L+ +
Sbjct: 318 YTKL------EEKHNEESVSKKNIQATLH-QKDLDCQQLQSRLSASETSLHRIHVELSEK 370
Query: 126 -----KLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEV 180
KL ++ +++ Y LK + + +++ ++ QLQ + LH L + ++
Sbjct: 371 GEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQL 430
Query: 181 QKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRG 240
+ + + + + KE++ L+ +L +L K+K L + + D +
Sbjct: 431 GEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQH--QLDKTKQ 488
Query: 241 SWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELK--KVLQQMKKEMISLLSPQKKK 298
+ + ++ + ND E +QI ++ +++ + L Q KE ISLL +++
Sbjct: 489 QHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKERED 548
Query: 299 PRERVDDSTG--TVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKL 356
++ G V++ ++E L + QLT ++ Q K E L
Sbjct: 549 LYAKIQAGEGETAVLNQLQEKNHTLQEQV----------TQLTEKLKNQSESHKQAQENL 598
Query: 357 DNQV--SKVHLEGFNDEDVISRQ-----------DHEQETEKLELEIQQCKEMI------ 397
+QV K HL D V+S + + +++ +L+++I+ E++
Sbjct: 599 HDQVQEQKAHLRAAQDR-VLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAA 657
Query: 398 KTQQQL-LQQQLATAYD----------------DDTTSLLRDCYLLEEKERLKEEWSLFK 440
KT Q+ LQ L TA + D T+ L+D E +L+ +K
Sbjct: 658 KTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQD--KQEHCSQLESHLKEYK 715
Query: 441 EQKKNFERERRSFTEAAIRL---GLERKAFEEERASWLKQQ 478
E+ + E++ +L LE KA +E+ L+QQ
Sbjct: 716 EKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQ 756
Score = 38.5 bits (88), Expect = 0.018
Identities = 97/437 (22%), Positives = 192/437 (43%), Gaps = 74/437 (16%)
Query: 63 EQSISYLDQELTTFGFPSLYEESKGKETKRE-LNIVAVLNCMNELLVLQR--KNLLAQEN 119
EQ ++ L +EL ++ ++ K + +R + VAVL EL+ +Q N+ +
Sbjct: 190 EQKVTRLTEELNKEA--TVIQDLKTELLQRPGIEDVAVLK--KELVQVQTLMDNMTLERE 245
Query: 120 VETQNLKLGSDMDHLQSCY-------SKLKEQLETSRREM-IGLQERDR------QLQCK 165
E++ LK + LQS Y S+L+ +L +E+ + +QE + +L K
Sbjct: 246 RESEKLK--DECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQK 303
Query: 166 NRNL-HQLLKNEKD--EVQKLQNIIASRATQYNHDMKRKEREYNKLKER-------LHQL 215
N+ L LLK E+D ++++ N + + +K+ + +L+ R LH++
Sbjct: 304 NQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRI 363
Query: 216 VMNKKDK-----KIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQI 270
+ +K K+ ++ + + ++ + R E E + + L Q +I
Sbjct: 364 HVELSEKGEATQKLKEELSEVETKYQHLKAEFKQ-LQQQREEKEQHGLQL------QSEI 416
Query: 271 LMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLS 330
+++L + +Q+ E L Q++ E++ D V +D++ L
Sbjct: 417 NQLHSKLLETERQL-GEAHGRLKEQRQLSSEKLMDKEQQV-ADLQLKLSRLE-------- 466
Query: 331 CETVREQLTNSIRKQWRILKS---HVEK--LDNQVSKVHLEGFNDEDVISRQ--DHEQET 383
E ++E++TNS Q ++ K+ H E+ L + E ND + + RQ D +Q+
Sbjct: 467 -EQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKI 525
Query: 384 EKLELEIQQCKEMIKTQQQLLQQQLATAY-----DDDTTSLLRDCYLLEEKERLKEEWSL 438
+ LE +Q+ KE I LL+++ Y + T++L L E+ L+E+ +
Sbjct: 526 QNLEALLQKSKENI----SLLEKEREDLYAKIQAGEGETAVLNQ--LQEKNHTLQEQVTQ 579
Query: 439 FKEQKKNFERERRSFTE 455
E+ KN + E
Sbjct: 580 LTEKLKNQSESHKQAQE 596
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 60.5 bits (145), Expect = 5e-09
Identities = 94/459 (20%), Positives = 192/459 (41%), Gaps = 80/459 (17%)
Query: 59 EDNIEQSISYLDQELT-------TFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQR 111
ED I++ Y+D + ++ S+ + + K+T + VA L+ E L+
Sbjct: 588 EDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVA-LDAKRESAFLRS 646
Query: 112 KNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQER------------- 158
+NL +E ++ +L + +++ + QLE ++ + L++
Sbjct: 647 ENLELKEKMK----ELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTS 702
Query: 159 ------------DRQLQCKNRNLHQLLKNEKDEVQKLQN--IIASRATQYNHDMKRKERE 204
+ +L+ K +L + L E +E + L+ I+ S +++R +E
Sbjct: 703 LIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKE 762
Query: 205 YNKLKERLHQLVMNKKDKKIA---------MDILNYVGRADGKRGSWRTGKTEARNEDEM 255
E LH ++ ++KDK + +L +G+ + ++ E +
Sbjct: 763 IQDKSEELH-IITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQN 821
Query: 256 YKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTG---TVIS 312
+K L D+E + K +L EN ++M +E+++L K ++ D S G T +S
Sbjct: 822 FKTLHMDFEQKYKMVLEEN-------ERMNQEIVNL-----SKEAQKFDSSLGALKTELS 869
Query: 313 DVEEDAGELSRESMWDLS-CETVREQLTN---SIRKQWRILKSHVEKLDNQVSKVHLEGF 368
++ E +RE L+ E ++EQL N +++ R EKL + +V
Sbjct: 870 YKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQ 929
Query: 369 NDEDVISRQDHEQ-ETEKLELEIQQCKEM-IKTQQQLLQQQLATAYDDDTTSLLRDCYLL 426
+D+ Q+ Q E ++L+ +I M I TQ+QL + +T + L
Sbjct: 930 EKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTL------ 983
Query: 427 EEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERK 465
K ++ EE S ++N + F + + G+++K
Sbjct: 984 --KSKISEEVSRNLHMEENTGETKDEFQQKMV--GIDKK 1018
Score = 52.8 bits (125), Expect = 9e-07
Identities = 109/466 (23%), Positives = 198/466 (42%), Gaps = 104/466 (22%)
Query: 100 LNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKL---KEQLETSRREMIGLQ 156
L+ ++E+ LL QEN+E++ L +D D+L Y +L KE++E +E L
Sbjct: 476 LDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLD 535
Query: 157 E---------RDRQLQCKNR--NLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREY 205
E +D+++Q + NL L+K+ + Q L+N ++S+ ++ KE +
Sbjct: 536 EFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVEL----LREKEDQI 591
Query: 206 NKLKE-----RLHQLVMN-----------KKDKKIAMDILNYVGRADGKRGSWRTGKTEA 249
KL+E +L + M+ K+ K+ D A + R+ E
Sbjct: 592 KKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLEL 651
Query: 250 RNEDE----MYKILLNDYEYRQKQILME---NAELKKVLQQMKKEMISLLS-PQKKKPRE 301
+ + + YK + ND + Q Q+ + +L+K LQ E+ L S K P++
Sbjct: 652 KEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKD 711
Query: 302 ---------RVDDSTGTVISDVEEDAGELSRESMWDLS--------CETVREQLTNSIRK 344
++ D + +VEE+ E RE + LS E +R+++ + +
Sbjct: 712 LLCNLELEGKITDLQKELNKEVEEN--EALREEVILLSELKSLPSEVERLRKEIQDK-SE 768
Query: 345 QWRILKSHVEKLDNQVSKVHLE----------GFNDEDVISRQDHEQETEK-------LE 387
+ I+ S +KL ++V VH E G +D+ + Q + + T++ L
Sbjct: 769 ELHIITSEKDKLFSEV--VHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLH 826
Query: 388 LEIQQCKEMIKTQQQLLQQQL------ATAYDDD----TTSLLRDCYLLEEK-----ERL 432
++ +Q +M+ + + + Q++ A +D T L L+EK ERL
Sbjct: 827 MDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERL 886
Query: 433 KEEWSLFKEQKKN-------FERERRSFTEAAIRLGLERKAFEEER 471
E L KEQ +N ERE+ TE + E K +E+
Sbjct: 887 NEMEQL-KEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEK 931
Score = 46.6 bits (109), Expect = 7e-05
Identities = 87/392 (22%), Positives = 158/392 (40%), Gaps = 98/392 (25%)
Query: 103 MNELLVLQRKNLLAQENVETQNLKLGS--------------DMDHLQSCYS-------KL 141
+ E Q+ NL EN+ET+N++L + D L+S +L
Sbjct: 1649 LKEQFETQKLNL---ENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQL 1705
Query: 142 KEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRK 201
KE L RE I RD + Q + + +H LK ++ + KL+ I++ + + ++ K
Sbjct: 1706 KENL----RETI---TRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDL 1758
Query: 202 EREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLN 261
E + LK + L + ++ + M + D RG + D++ +
Sbjct: 1759 EHSNDALKAQ--DLKIQEELRIAHMHLKEQQETIDKLRG------IVSEKTDKLSNM--- 1807
Query: 262 DYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGEL 321
QK + NA+L++ +Q++K L++ +K DV E ++
Sbjct: 1808 -----QKDLENSNAKLQEKIQELKANEHQLITLKK----------------DVNETQKKV 1846
Query: 322 SRESMWDLSCETVREQLTNSIRKQWRIL-KSHVEKLDNQVSKVHLEGFNDEDVISRQDHE 380
S EQL I+ Q L K +E L N K+H + V+ +D+
Sbjct: 1847 SE-----------MEQLKKQIKDQSLTLSKLEIENL-NLAQKLHENLEEMKSVMKERDNL 1894
Query: 381 QETEK-LELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLF 439
+ E+ L+LE Q KE ++ + RD LE ++ LK L
Sbjct: 1895 RRVEETLKLERDQLKESLQETK------------------ARD---LEIQQELKTARMLS 1933
Query: 440 KEQKKNFERERRSFTEAAIRLGLERKAFEEER 471
KE K+ ++ R +E I++ +K ++ +
Sbjct: 1934 KEHKETVDKLREKISEKTIQISDIQKDLDKSK 1965
Score = 45.4 bits (106), Expect = 2e-04
Identities = 117/611 (19%), Positives = 231/611 (37%), Gaps = 109/611 (17%)
Query: 80 SLYEESKGKETKRELNIVAVLNCMNELLVL-----QRKNLLAQENVET--QNLKLGSDMD 132
S+ E + +T + NI + EL +L +++ ++AQE + +L D
Sbjct: 1061 SVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCD 1120
Query: 133 HLQSCYSKLKE---QLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIAS 189
L KLKE QL+ +++++ +QE ++Q K +E++ L+N + +
Sbjct: 1121 RLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKK-----------INEIENLKNELKN 1169
Query: 190 RATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDI-LNYVGRADGKRGSWRTGKTE 248
+ H + KL E ++ K++K+ ++ ++ D RG R +
Sbjct: 1170 KELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEAT 1229
Query: 249 ARNEDEMYKILLNDYEYRQKQI-------------LMENAELKKVLQQMKKEMISLLSPQ 295
E KI + Q+ I ++ +L+K ++++E+ L Q
Sbjct: 1230 GLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQ 1289
Query: 296 KKKPRERVDDSTGTVISDVE--------EDAGELSR-------------ESMWDLSCETV 334
+ P + T ++++E +D+ L+R ES ++ T
Sbjct: 1290 ELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTK 1349
Query: 335 REQLTNSIRKQWRI----LKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEI 390
+I++ + LK H+ + ++K+ E ++ ++ + ET K+ E+
Sbjct: 1350 ERDNLKTIKEALEVKHDQLKEHIRE---TLAKIQESQSKQEQSLNMKEKDNETTKIVSEM 1406
Query: 391 QQCK-----------EMI---KTQQQLLQQQLATAYDDDTTSLLRDCYL----------- 425
+Q K EM+ K Q+ + + A + D L++
Sbjct: 1407 EQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIK 1466
Query: 426 ------LEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQF 479
LE +E LK KEQ++ R + +E + +K E A K Q
Sbjct: 1467 EIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLE---AINDKLQN 1523
Query: 480 LNMTTFDHQNSENVKLFSAFSGSSDWDNLIVHSRQPQKKPHSVSNGSPVCMSKLTKSLPA 539
++ + N+K S + N + ++ +K S M +LT L
Sbjct: 1524 KIQEIYEKEEQFNIKQISEV---QEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQE 1580
Query: 540 SPSTSDFCQTRSCISEHSSINVLNITAEEIKPNQVGGERTNQKWSVASRPGSQEGCYSGC 599
S + + I E + + A +I+ +Q+ + N K VA SQE Y
Sbjct: 1581 SQE-----EIQIMIKEKEEMKRVQ-EALQIERDQL---KENTKEIVAKMKESQEKEYQFL 1631
Query: 600 SLSYTNSHVEK 610
++ N EK
Sbjct: 1632 KMTAVNETQEK 1642
Score = 45.4 bits (106), Expect = 2e-04
Identities = 85/408 (20%), Positives = 177/408 (43%), Gaps = 55/408 (13%)
Query: 110 QRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNL 169
+++ L + + + K+ S+M+ + S L ++E EM+GL +R LQ + +
Sbjct: 1385 KQEQSLNMKEKDNETTKIVSEMEQFKPKDSALL-RIEI---EMLGLSKR---LQESHDEM 1437
Query: 170 HQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDIL 229
+ K EKD++Q+LQ ++ S + Q ++K ++ + +E L K+++ ++ L
Sbjct: 1438 KSVAK-EKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINEL 1496
Query: 230 NYVGRADGKRGSWRTGKTEARN---EDEMYKILLNDYEYRQKQI--LMENAELKKVLQQM 284
S + EA N ++++ +I + ++ KQI + E K ++
Sbjct: 1497 RVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEH 1556
Query: 285 KKEMISLLSPQKKKPRE---RVDDSTGTV---ISDVEE-----DAGELSRESMWDLSCET 333
+K S L + K E R+ +S + I + EE +A ++ R+ + + + E
Sbjct: 1557 RKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEI 1616
Query: 334 VREQLTNSIRKQWRILK-----------SHVEKLDNQ--VSKVHLEGFNDEDVISRQDHE 380
V ++ S K+++ LK +E L Q K++LE E++ Q
Sbjct: 1617 V-AKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILH 1675
Query: 381 QETEKLEL------EIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKE 434
+ E++ +++ +E +K ++ L++ L D LE++E LK
Sbjct: 1676 ENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRD----------LEKQEELKI 1725
Query: 435 EWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFLNM 482
KE ++ ++ R +E + +K E + LK Q L +
Sbjct: 1726 VHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA-LKAQDLKI 1772
Score = 37.7 bits (86), Expect = 0.031
Identities = 79/376 (21%), Positives = 159/376 (42%), Gaps = 68/376 (18%)
Query: 43 IPLSKNVHSFFSAFCTEDNIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNC 102
I L K+V+ + +++ I DQ LT L E+ K N+ + +
Sbjct: 1833 ITLKKDVNETQKKVSEMEQLKKQIK--DQSLT---LSKLEIENLNLAQKLHENLEEMKSV 1887
Query: 103 MNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQL 162
M E R NL E + LKL D +LKE L+ ++ RD ++
Sbjct: 1888 MKE-----RDNLRRVE----ETLKLERD---------QLKESLQETK-------ARDLEI 1922
Query: 163 QCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDK 222
Q + + L K K+ V KL+ I+ + Q + K ++ ++L++++ +L KK+
Sbjct: 1923 QQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQEL--QKKEL 1980
Query: 223 KIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQ 282
++ + + V + K NE E K + + M+N +L K L
Sbjct: 1981 QL-LRVKEDVNMSHKK-----------INEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLH 2028
Query: 283 QMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSI 342
+ +E I +++ ++ + R R+ +S +E D + M R++ + +
Sbjct: 2029 ESLEE-IRIVAKERDELR-RIKESL-----KMERDQFIATLREM------IARDRQNHQV 2075
Query: 343 RKQWRIL---KSHV-EKLDNQVSKVH--LEGFNDEDVISRQDHEQETEKLELEIQQCKEM 396
+ + R+L + H+ E L + S++ L+ +++ D DH + +L L++++ E
Sbjct: 2076 KPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMD-----DHYECLNRLSLDLEKEIEF 2130
Query: 397 IKTQQQLLQQQLATAY 412
K ++ L+ Y
Sbjct: 2131 QKELSMRVKANLSLPY 2146
Score = 32.3 bits (72), Expect = 1.3
Identities = 79/429 (18%), Positives = 162/429 (37%), Gaps = 66/429 (15%)
Query: 83 EESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQE----NVETQNLKLGSDMD-HLQSC 137
EE K E++ + + ELL+ + L Q+ + E ++LKL +MD H++
Sbjct: 2185 EEQHESINKFEMDFIDEVEKQKELLI--KIQHLQQDCDVPSRELRDLKLNQNMDLHIEEI 2242
Query: 138 YSKLKE-----------QLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNI 186
E Q+ ++R+EM E + L ++ E D + ++ N
Sbjct: 2243 LKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNF 2302
Query: 187 IASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGK 246
+R ++ E + + Q + + K+K + NY +
Sbjct: 2303 FNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKL-FKNYQTLKTSLASGAQVNP 2361
Query: 247 TEARNEDEMYKILLNDYEYRQKQILMEN-AELKKVLQQMKKEMISLLSPQKKKPRERVDD 305
T N++ R Q+ E EL+ L + K+ + S K +E +
Sbjct: 2362 TTQDNKNP-------HVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKEL--E 2412
Query: 306 STGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHL 365
T +I+ ++ E ++ + + ET+ + L + + + K +E L ++ K+ L
Sbjct: 2413 VTNDIIAKLQAKVHESNK--CLEKTKETI-QVLQDKVALGAKPYKEEIEDLKMKLVKIDL 2469
Query: 366 EGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRD--- 422
E + ++ E+E + ++ KE+I+ LL++ L + TS++ +
Sbjct: 2470 EKMK-----NAKEFEKEISATKATVEYQKEVIR----LLRENLRRSQQAQDTSVISEHTD 2520
Query: 423 ----------------------CYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRL 460
L E RL++E S K+Q + +++ L
Sbjct: 2521 PQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHL 2580
Query: 461 GLERKAFEE 469
E K ++E
Sbjct: 2581 SNEVKTWKE 2589
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 60.1 bits (144), Expect = 6e-09
Identities = 78/387 (20%), Positives = 156/387 (40%), Gaps = 57/387 (14%)
Query: 119 NVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKD 178
++ +QN K+ + +D Y L++ +E RRE+ L ER+++L + Q++
Sbjct: 706 DLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQ 765
Query: 179 EVQKLQNIIASRATQYNHDMKRKEREYNKLKE-RLHQLVMNKKDKKIAMDILNYVGRADG 237
+++ +A + + +KE+E KL E RL Q +++ +A
Sbjct: 766 DLRGANEKLA--VAEVRAENLKKEKEMLKLSEVRLSQ----QRESLLA------------ 807
Query: 238 KRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKK 297
E +LL + + Q + E K+ L +++ +S KK
Sbjct: 808 --------------EQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKK 853
Query: 298 KPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLD 357
K V + T+ +++ + R+ + + ++L + +K+ LK H+ ++
Sbjct: 854 KLENEV-EQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNME 912
Query: 358 NQVSKVHL------EGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATA 411
QV+ + N EDV D + + E ++ KE +KT ++Q
Sbjct: 913 VQVASQSSQRTGKGQPSNKEDV---DDLVSQLRQTEEQVNDLKERLKTSTSNVEQ----- 964
Query: 412 YDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEER 471
Y TSL +E L +E + +E +KN E + E +L + E+E+
Sbjct: 965 YQAMVTSL---------EESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEK 1015
Query: 472 ASWLKQQFLNMTTFDHQNSENVKLFSA 498
+ + + + Q SE K S+
Sbjct: 1016 QELQDDKRRAIESMEQQLSELKKTLSS 1042
Score = 58.2 bits (139), Expect = 2e-08
Identities = 78/358 (21%), Positives = 148/358 (41%), Gaps = 57/358 (15%)
Query: 108 VLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREM-IGLQERDRQLQCKN 166
+L+R ++ + +Q KL ++ HL+ EQ T R + + L + RQL +
Sbjct: 825 ILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTET 884
Query: 167 RNLH----QLLKNEKDEV----QKLQNI---IASRATQYN---------------HDMKR 200
NLH +LLKN + E+ Q L N+ +AS+++Q +++
Sbjct: 885 -NLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQ 943
Query: 201 KEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILL 260
E + N LKERL N + + + L + + E R E+
Sbjct: 944 TEEQVNDLKERLKTSTSNVEQYQAMVTSL------EESLNKEKQVTEEVRKNIEVRLKES 997
Query: 261 NDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGE 320
+++ + ++ LME + K+ LQ K+ I + Q + ++ + V ++ +
Sbjct: 998 AEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTA 1057
Query: 321 LSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLD------NQVSKVHLEGFNDEDVI 374
LS E C+ + + K R L H ++ QVSK+
Sbjct: 1058 LSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKM---------AS 1108
Query: 375 SRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERL 432
RQ E+ T+K E ++ +CK + ++++L+ D+ + + C LE++ RL
Sbjct: 1109 VRQHLEETTQKAESQLLECKASWEERERMLK--------DEVSKCVCRCEDLEKQNRL 1158
Score = 53.5 bits (127), Expect = 6e-07
Identities = 93/489 (19%), Positives = 197/489 (40%), Gaps = 92/489 (18%)
Query: 89 ETKRELNIVAVL-NCMNELLVLQRKNLLAQENVETQNLKLGS--------DMDHLQSCYS 139
ET LN +L N E+ L++ + V +Q+ + D+D L S
Sbjct: 883 ETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLR 942
Query: 140 KLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK---DEVQKLQNIIASRATQYNH 196
+ +EQ+ + + Q Q +L + L EK +EV+K + + ++
Sbjct: 943 QTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQT 1002
Query: 197 DMKRK----EREYNKLKERLHQLVMNKKD-----KKIAMDILNYVGRADGKRGSWRTGKT 247
+++K E+E +L++ + + + + KK + N V A + + + +
Sbjct: 1003 QLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQ 1062
Query: 248 EARNE-DEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDS 306
+AR + E KI + ++++++ A+++ + Q KE +S ++ R+ ++++
Sbjct: 1063 QARRDCQEQAKIAVEAQNKYERELMLHAADVEAL--QAAKEQVSKMA----SVRQHLEET 1116
Query: 307 TGTVISDVEEDAGELSRESMWDLSCETVREQLTNSI------RKQWRILKSHVEKLDNQV 360
T S + L ++ W+ ++++++ + KQ R+L +EKL ++V
Sbjct: 1117 TQKAESQL------LECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKV 1170
Query: 361 S-------------KVHLEGFNDEDVIS-----RQDHE-----------------QETEK 385
+ EG + E ++ R++ E Q E
Sbjct: 1171 VASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVEL 1230
Query: 386 LELEIQQCKEMIKTQQQLLQ---------QQLATAYDDDTTSLLRDCYLLEEKERLKEEW 436
LE E+Q+ ++ + +++ +Q ++L + + + L EEKERL+++
Sbjct: 1231 LERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDL 1290
Query: 437 SLFKEQKKNFERERRSFTEAAIRLG-------LERKAFEEERASW-LKQQFLNMTTFDHQ 488
+ + + E + EA L E+K EE+ W + Q L D
Sbjct: 1291 QQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPD 1350
Query: 489 NSENVKLFS 497
E KL S
Sbjct: 1351 TEEYRKLLS 1359
Score = 52.0 bits (123), Expect = 2e-06
Identities = 92/418 (22%), Positives = 182/418 (43%), Gaps = 53/418 (12%)
Query: 82 YEESKGKETKRELNIVAVLNCMNELLVLQR-KNLLAQENVETQNLKLGSDMD-HLQSCYS 139
+E K +E + C + L L++ N L + + L++ D + +QS ++
Sbjct: 55 FEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFT 114
Query: 140 KLKEQLETSRREMIGLQERDRQ----LQCKNRNLHQLLKNE---KDEVQ-KLQNIIASRA 191
+ KE+LE +R++I ER Q L + L++ LK K E+Q KL + AS
Sbjct: 115 RTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDV 174
Query: 192 TQYNHDMKRKEREYNKLKERLH-QLVMNKKDKKIAMDILNYVGRADGK-----RGSWRTG 245
+ +K +E+ + KE LH Q + K D L +GR G + +
Sbjct: 175 S-----VKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENK 229
Query: 246 KTEARNEDEMYKILLNDYEYRQKQI---LMENAELKKVLQQMKKEMISLLSPQKKKP--- 299
K E +E L E+ QK + L + E K+ M+++ + L+ K
Sbjct: 230 KEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLY 289
Query: 300 RERVDDS---TGTVISDVEE------DAGELSRESMWD--LSCETVREQLTNSIRKQWRI 348
+ DDS + + VEE +AGE + +++ D L E ++Q+ + ++
Sbjct: 290 KSAADDSEAKSNELTRAVEELHKLLKEAGE-ANKAIQDHLLEVEQSKDQMEKEMLEKIGR 348
Query: 349 LKSHVEKLDNQVSKVHLEG--FNDEDVISRQDHEQETEKLELEIQQCKEM----IKTQQQ 402
L+ +E ++ +S +G ++E++ + K+ + E+ ++TQ Q
Sbjct: 349 LEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQ 408
Query: 403 LLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRL 460
LL ++L + YL E + ++ + + K Q++ +ER +++ +++L
Sbjct: 409 LLLEKLENKRINK--------YLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKL 458
Score = 41.2 bits (95), Expect = 0.003
Identities = 80/371 (21%), Positives = 149/371 (40%), Gaps = 56/371 (15%)
Query: 58 TEDNIEQSISYLDQELTTFGFPSLYEESK-GKETKRELNIVAVLNCMNELLVLQRKNLLA 116
T + + Q + YL +++ L E+ K TK EL + +++ V R+ L
Sbjct: 130 TNERLSQELEYLTEDVKR-----LNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLE 184
Query: 117 QENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNE 176
QE ++ H Q+ + + + +T +G ++ + L+ K L+N+
Sbjct: 185 QEK----------ELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCN-----LENK 229
Query: 177 KDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVM------NKKDKKIAMDILN 230
K+EV +L+ + T H K E KLKE Q N+ + I + L
Sbjct: 230 KEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNL- 288
Query: 231 YVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMIS 290
Y AD R +E++K LL + K I E+++ QM+KEM+
Sbjct: 289 YKSAADDSEAK---SNELTRAVEELHK-LLKEAGEANKAIQDHLLEVEQSKDQMEKEMLE 344
Query: 291 LLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLS-CETVREQLTNSIRKQWRIL 349
+ + +K E +D ++S + LS E + +S ++ K +
Sbjct: 345 KIG-RLEKELENAND----LLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELY 399
Query: 350 KSHV--------EKLDNQVSKVHLEGFNDE-----DVISRQDHEQE-----TEKLELEIQ 391
++V EKL+N+ +L+ E ++ RQ E E L ++++
Sbjct: 400 NAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLE 459
Query: 392 QCKEMIKTQQQ 402
Q + I+ Q+
Sbjct: 460 QAMKEIQRLQE 470
Score = 31.6 bits (70), Expect = 2.2
Identities = 44/240 (18%), Positives = 108/240 (45%), Gaps = 32/240 (13%)
Query: 81 LYEESKGKETKRELN-IVAVLNCMNELLVLQRKNL-LAQENVETQNLKLGSDMDHLQSCY 138
L E+ + K + L+ IV + +L QR+ AQ+ V + ++KL M +Q
Sbjct: 410 LLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQ--- 466
Query: 139 SKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDM 198
+L+E + + ++ L+ +R+++ + ++L Q ++ E+++ + NH +
Sbjct: 467 -RLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARG---------NHVI 516
Query: 199 KRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRT-------GKTEARN 251
+ +E + ++ + I+ +++Y + ++ + R G+T R
Sbjct: 517 RDEE---------VSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETRERE 567
Query: 252 EDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVI 311
E E + + + + + L E +L+K +Q + +++ + Q+ R + +TG I
Sbjct: 568 EQETTSSKITELQLKLESALTELEQLRK-SRQHQMQLVDSIVRQRDMYRILLSQTTGVAI 626
Score = 29.6 bits (65), Expect = 8.5
Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 28/174 (16%)
Query: 59 EDNIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQE 118
E + + S + +Q ++ L E ETK + V N L K A+
Sbjct: 1457 ETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQK---TLSEKETEAR- 1512
Query: 119 NVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDR------------------ 160
N++ Q ++L S++ L+ Q E R+++ +E+ R
Sbjct: 1513 NLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKD 1572
Query: 161 QLQCKNRNLHQ---LLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKER 211
QL +N L Q L +KDE L I + +QY + R ERE + +ER
Sbjct: 1573 QLTKENEELKQRNGALDQQKDE---LDVRITALKSQYEGRISRLERELREHQER 1623
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 59.3 bits (142), Expect = 1e-08
Identities = 114/552 (20%), Positives = 222/552 (40%), Gaps = 79/552 (14%)
Query: 83 EESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLK 142
E KE EL + V ++ VLQ KN Q+ +E LQS Y L+
Sbjct: 2547 EHQLWKEQNLELRNLTV-ELEQKIQVLQSKNASLQDTLEV-----------LQSSYKNLE 2594
Query: 143 EQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKE 202
+LE ++ + + E+ ++ K L + + + +LQ ++ + +++
Sbjct: 2595 NELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLL 2654
Query: 203 REYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLND 262
E K++L +L + + K ++D ++ K + GK R E Y++ L++
Sbjct: 2655 EEIKSSKDQLKELTLENSELKKSLDCMH-------KDQVEKEGK--VREEIAEYQLRLHE 2705
Query: 263 YEYRQKQILME-NAELKKVLQQMKKEMIS---LLSPQK------KKPRERVDDSTGTVIS 312
E + + +L++ N + + +Q ++++ S LS QK K +E +++S
Sbjct: 2706 AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQ 2765
Query: 313 DVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDED 372
+E EL + M +L + N ++K+ + ++ L ++ E +
Sbjct: 2766 ILE----ELKKTKMDNL-------KYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQK 2814
Query: 373 VISRQDHEQETEK----LELEIQQCKEMIKTQQQLLQQQL--ATAYDDDTTSLLRDCYLL 426
+S+ QE +K ++ ++ + IK ++ L+++ A Y D SLL L
Sbjct: 2815 ELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKL 2874
Query: 427 EE-KERLKEEWS-LFKEQKKNFERER-------------RSFTEAAIRLGLERKAFEEER 471
E+ KE L+ + + L +Q K R S TE + G + + + +R
Sbjct: 2875 EKAKEMLETQVAHLCSQQSKQDSRGSPLLGPVVPGPSPIPSVTEKRLSSGQNKASGKRQR 2934
Query: 472 ASWLKQQFLNMTTFDHQNSENVKLFSAFSGSSDWDNLIVHSRQPQKKPHSVSNG------ 525
+S + + T ++ + SG ++ +P+ P V G
Sbjct: 2935 SSGIWENGRGPTPATPESFSKKSKKAVMSGIHPAEDTEGTEFEPEGLPEVVKKGFADIPT 2994
Query: 526 ---SPVCMSKLTKSLPASPSTSDFCQTRSCISEHSSINVLNITAEEIKPNQVGGERTNQK 582
SP + + T + SP + + S+ N+ AE KP GG R +QK
Sbjct: 2995 GKTSPYILRRTTMATRTSPRLA----AQKLALSPLSLGKENL-AESSKPT-AGGSR-SQK 3047
Query: 583 WSVASRPGSQEG 594
VA R G
Sbjct: 3048 VKVAQRSPVDSG 3059
Score = 56.2 bits (134), Expect = 9e-08
Identities = 110/472 (23%), Positives = 196/472 (41%), Gaps = 92/472 (19%)
Query: 82 YEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKL 141
YEE K ++T + +C + + LL Q E +NL+ S ++HL++C K
Sbjct: 609 YEELKEEKT--------LFSCWKS----ENEKLLTQMESEKENLQ--SKINHLETCL-KT 653
Query: 142 KEQLETSRREMIGLQERDRQ-LQCKNRNLHQLL--KNEKDEVQKLQNIIASRATQYNHDM 198
++ E + E DR+ L + RNLH +L K+ + E QKL + + +++
Sbjct: 654 QQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQK 713
Query: 199 KRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKI 258
+KE E LK QL +D + + +L+ E ++D Y+
Sbjct: 714 HQKEIENMCLK--TSQLTGQVEDLEHKLQLLS----------------NEIMDKDRCYQD 755
Query: 259 LLNDYEYRQKQILMENAEL-------KKVL---QQ--MKKEMISLLSPQKKKPRERVD-- 304
L +YE + + ++A L + +L QQ M +++ Q P ER +
Sbjct: 756 LHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECR 815
Query: 305 -----DSTGTVISDVEEDAGELSRESMWDLS------CE---TVREQLTNSIRKQWRILK 350
+ I D+ E S ES ++ CE ++ ++ ++ K ++ +
Sbjct: 816 LEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQ 875
Query: 351 SHVEKLDNQVSKVHLEGFNDEDVISRQDHEQET----EKLELEIQQCKEMIKTQQQLLQQ 406
S V + ++SK+ ED + Q+ ET E E E+Q + ++T+Q +Q+
Sbjct: 876 SFVAETSQRISKL------QEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQE 929
Query: 407 QLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKN-FERERRSFTEAAIRLGLERK 465
+ LL D L+E + L E SL K++ + +R E L E
Sbjct: 930 L------KKSNHLLEDS--LKELQLLSETLSLEKKEMSSIISLNKREIEE----LTQENG 977
Query: 466 AFEEERASWLKQQFLNM----TTFDHQNSENVKLFSAFSGSSDWDNLIVHSR 513
+E AS L Q+ +N+ +F + E K S S + LI+ R
Sbjct: 978 TLKEINAS-LNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQR 1028
Score = 45.1 bits (105), Expect = 2e-04
Identities = 82/391 (20%), Positives = 165/391 (42%), Gaps = 46/391 (11%)
Query: 126 KLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQN 185
+L + L++ ++L+ +L+ +EM G + ++LQ + L ++ + K ++
Sbjct: 282 QLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRD 341
Query: 186 IIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTG 245
+ QY+ + +Y L+++L KK+ D+ A+ R S
Sbjct: 342 ELVRTTAQYD----QASTKYTALEQKL---------KKLTEDLSCQRQNAESARCSLEQK 388
Query: 246 KTEARNE-DEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVD 304
E E E ++ ++ + A L + LQQ K M ++L + +++
Sbjct: 389 IKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQ-AKNMHNVLQAE----LDKLT 443
Query: 305 DSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNS---IRKQWRILKSHVEKLDNQVS 361
+ +++EE +L R + + +L S ++K+ +LKSH E+ +V
Sbjct: 444 SVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVC 503
Query: 362 KVHLEGFNDEDVISRQDHEQETEKL-----ELEIQQCKEMIKTQQ-QLLQQQLATAYDDD 415
+ E N + +++ + E K E ++ +E I Q+ L ++L A D
Sbjct: 504 HLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVAD- 562
Query: 416 TTSLLRDCY--LLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERAS 473
RDC LL+++E E+ ++ E+E ++ A L L++K +EE
Sbjct: 563 -LEKQRDCSQDLLKKREHHIEQ---LNDKLSKTEKESKALLSA---LELKKKEYEE---- 611
Query: 474 WLKQQFLNMTTFDHQNSENVKLFSAFSGSSD 504
LK++ T F SEN KL + +
Sbjct: 612 -LKEE---KTLFSCWKSENEKLLTQMESEKE 638
Score = 44.7 bits (104), Expect = 3e-04
Identities = 65/349 (18%), Positives = 142/349 (40%), Gaps = 29/349 (8%)
Query: 145 LETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQ-----------KLQNIIASRATQ 193
L R E++ + Q K L Q LK +++ L+ I + +
Sbjct: 336 LNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKE 395
Query: 194 YNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNED 253
+ ++ R++R + L + Q+ + ++ V +A+ + + + E E+
Sbjct: 396 FQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEE 455
Query: 254 EMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRE--RVDDSTGTVI 311
K+ + ++ QI + EL++ +++MKKE L S ++K RE ++ +
Sbjct: 456 FKQKLCRAEQAFQASQI--KENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIK 513
Query: 312 SDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDE 371
+ + + S ET+ L I +Q L +EKL V+ + + +
Sbjct: 514 QCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLT--LEKLKLAVADLEKQRDCSQ 571
Query: 372 DVISRQDHEQE--------TEKLELEIQQCKEMIKTQQQLLQQQ--LATAYDDDTTSLLR 421
D++ +++H E TEK + E+ K + + L+++ L + + + LL
Sbjct: 572 DLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLT 631
Query: 422 DCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEE 470
+ EKE L+ + + + K + + + E L ++R+ E
Sbjct: 632 Q--MESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVE 678
Score = 44.7 bits (104), Expect = 3e-04
Identities = 70/370 (18%), Positives = 168/370 (45%), Gaps = 39/370 (10%)
Query: 81 LYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSK 140
L+ K KE +RE + + +++ L+R+ +++EN E L D ++ ++
Sbjct: 2136 LHIAEKLKEREREND-----SLKDKVENLERELQMSEENQELVIL----DAENSKAEVET 2186
Query: 141 LKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKR 200
LK Q+E R + + L+ + NL + ++ ++ ++ +L +++S + ++
Sbjct: 2187 LKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSS----FKSLLEE 2242
Query: 201 KEREYNKLKERLHQLV--MNKKDKKIAMDILNYVGRADGKRGSWRT------GKTEARNE 252
KE+ ++KE V + + K++ + G + + + ++ + + RN
Sbjct: 2243 KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 2302
Query: 253 DEMYKILLNDYEYRQKQILMENAE-------LKKVLQQMKKEMISLLSPQKKKPRERVDD 305
E + L E +Q +L + E LK ++ +++E+ + Q+ E ++
Sbjct: 2303 IEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALE-AEN 2361
Query: 306 STGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHL 365
S G V + + G +L T+R + N L + ++K ++S++ +
Sbjct: 2362 SKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEN--------LTNELQKEQERISELEI 2413
Query: 366 EGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYL 425
+ E+++ Q+ EQE +++ + EM++TQ + L +++A ++D ++ L
Sbjct: 2414 INSSFENIL--QEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNL 2471
Query: 426 LEEKERLKEE 435
+ E L+ E
Sbjct: 2472 SSQVECLELE 2481
Score = 38.1 bits (87), Expect = 0.024
Identities = 71/359 (19%), Positives = 155/359 (43%), Gaps = 40/359 (11%)
Query: 118 ENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK 177
E V+T+ L L D ++ Q L+E+L E L+ + K L QL + K
Sbjct: 1926 EVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMK 1985
Query: 178 DEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMN----KKDKKIAMDILNYVG 233
++ Q+L+ S ++ H ++ E E + E L L + KDK + L +
Sbjct: 1986 EKTQELE----SHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSL- 2040
Query: 234 RADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAE-LKKVLQQMKKEMISLL 292
++ S T+ E+++ ++ ++K++L++ +E L+ L + E +++
Sbjct: 2041 ----EKDSQALSLTKCELENQIAQL------NKEKELLVKESESLQARLSESDYEKLNVS 2090
Query: 293 SPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILK-- 350
+ E+ + + +S +E+ +L R E +R ++ +KQ I +
Sbjct: 2091 KALEAALVEKGEFALR--LSSTQEEVHQLRR------GIEKLRVRIEADEKKQLHIAEKL 2142
Query: 351 --------SHVEKLDNQVSKVHLEGFNDEDVI-SRQDHEQETEKLELEIQQCKEMIKTQQ 401
S +K++N ++ + N E VI ++ + E E L+ +I++ +K
Sbjct: 2143 KERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKV-F 2201
Query: 402 QLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRL 460
+L L + ++ T + L E ++L + E+K+ E + + ++ A+ +
Sbjct: 2202 ELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEM 2260
Score = 37.4 bits (85), Expect = 0.041
Identities = 61/259 (23%), Positives = 107/259 (41%), Gaps = 63/259 (24%)
Query: 276 ELKKVLQQMKKEMISLLSP-QKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETV 334
+LKK QQ + ++ SL + QK+K + + + GT + + E+ CE++
Sbjct: 29 KLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEI---------CESL 79
Query: 335 REQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCK 394
E+ I + ++ +S V + Q++ +++ EKLE E+++CK
Sbjct: 80 -EKTKQKISHELQVKESQVNFQEGQLNS----------------GKKQIEKLEQELKRCK 122
Query: 395 EMIKTQQQLLQ------QQLATAYDDDTTSLLRDCYLLEEK-ERLKEEWSLFKEQKKNFE 447
++ QQ Q T TT L Y K E LKE+++ E++K
Sbjct: 123 SELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERK--- 179
Query: 448 RERRSFTEAAIRLGLERKAFEEERASWLKQQFLNMTTFDHQNSENVKLFSAFSGSSDWDN 507
RL E KA + ++AS Q L T +H++ + S+
Sbjct: 180 -----------RLEAEVKALQAKKAS----QTLPQATMNHRDIARHQASSS--------- 215
Query: 508 LIVHSRQPQKKPHSVSNGS 526
V S Q +K P +S+ S
Sbjct: 216 --VFSWQQEKTPSHLSSNS 232
Score = 35.0 bits (79), Expect = 0.20
Identities = 84/439 (19%), Positives = 163/439 (37%), Gaps = 77/439 (17%)
Query: 12 LSSESKTISQYTSETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTEDNIEQSISYLDQ 71
+ +E I + + SL Q+L ++ L K S + ++ I L Q
Sbjct: 920 VETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLN-----KREIEELTQ 974
Query: 72 ELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLA-QENVETQNLKLGSD 130
E T +E + ++N++ + + K++ + + + L L
Sbjct: 975 ENGTL------KEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQR 1028
Query: 131 MDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASR 190
+ + Y L ++ + + QE++ +L+C L +N K+E+++L+ A
Sbjct: 1029 CEETGNAYEDLSQKYKAA-------QEKNSKLECLLNECTSLCENRKNELEQLKEAFAKE 1081
Query: 191 ATQYNHDMK-RKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEA 249
++ + +ER N + E + V ++ + N A G + T K E
Sbjct: 1082 HQEFLTKLAFAEERNQNLMLEL--ETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQ 1139
Query: 250 RNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLS-PQKKKPRERVDDSTG 308
N + +L EN +L KV+ + K E +L S P + +ER
Sbjct: 1140 -----------NKMQKEVNDLLQENEQLMKVM-KTKHECQNLESEPIRNSVKER------ 1181
Query: 309 TVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGF 368
E + + + + DL V+E +S Q V LE
Sbjct: 1182 ------ESERNQCNFKPQMDLE---VKEISLDSYNAQ----------------LVQLEAM 1216
Query: 369 NDEDVISRQDHEQETEKLELEIQQCKEMIKTQ--QQLLQQQLATAYDDDTTSLLRDCYLL 426
+ Q+ E+E E L+ E+Q + ++T Q + Q++ S L+DC +
Sbjct: 1217 LRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEI---------SGLKDCEID 1267
Query: 427 EEKERLKEEWSLFKEQKKN 445
E++ + L Q N
Sbjct: 1268 AEEKYISGPHELSTSQNDN 1286
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 58.9 bits (141), Expect = 1e-08
Identities = 98/474 (20%), Positives = 194/474 (40%), Gaps = 72/474 (15%)
Query: 63 EQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVET 122
E +S + TF P L +E + K E + + + + V+Q +N Q ++
Sbjct: 176 ESKLSSSMNSIKTFWSPELKKERALR--KDEASKITIWK--EQYRVVQEENQHMQMTIQA 231
Query: 123 --QNLKLGSDMDHL----------QSCYSKLKEQL--------ETSRREMIGLQERDRQL 162
L++ D++ L + C ++L E+ E +E+ L++ ++
Sbjct: 232 LQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEM 291
Query: 163 QCKNRNLHQLLKNEKDEVQKLQNIIASR-----ATQYNHD------------------MK 199
+ + Q L + ++KL ++ S+ AT+ +H+ ++
Sbjct: 292 ELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLE 351
Query: 200 RKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYK-- 257
+KE+E + L+E +H+ N D + + D K S G + E +M K
Sbjct: 352 QKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSN 411
Query: 258 --ILLNDYEYRQKQILMENAE---LKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVIS 312
+ + E KQ+ + + +K ++Q+K+E+ S K+ E + + +
Sbjct: 412 GALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSS-----KEAQWEELKKKAAGLQA 466
Query: 313 DVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGF---N 369
++ + ELSR+ L+ +T E LTN Q+ K H+E L ++
Sbjct: 467 EIGQVKQELSRKDTELLALQTKLETLTN----QFSDSKQHIEVLKESLTAKEQRAAILQT 522
Query: 370 DEDVISRQDHEQET--EKLELEIQQCKEMIKTQQQLLQ--QQLATAYDDDTTSLLRDCYL 425
+ D + + E+ET K +IQ E TQ + + + + L +
Sbjct: 523 EVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIEN 582
Query: 426 LEEKERLKE-EWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQ 478
L+E+ R KE + S KE+ K+ + + + T+ A+ E A +E LK+Q
Sbjct: 583 LQEQLRDKEKQMSSLKERVKSLQADTTN-TDTALTTLEEALAEKERTIERLKEQ 635
Score = 44.3 bits (103), Expect = 3e-04
Identities = 76/366 (20%), Positives = 143/366 (39%), Gaps = 48/366 (13%)
Query: 134 LQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQ 193
LQ L+EQL ++M L+ER + LQ N L ++ + + + I Q
Sbjct: 576 LQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQ 635
Query: 194 YNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARN-- 251
+ D + K+ E + K+ L KD K + +L G K S K A +
Sbjct: 636 RDRDEREKQEEIDNYKKDL-------KDLKEKVSLLQ--GDLSEKEASLLDLKEHASSLA 686
Query: 252 -----EDEMYKILLNDYEYRQKQILMENAELKKV----------------LQQMKKEMIS 290
+D K L E ++++ L ++LKK +Q +++E I+
Sbjct: 687 SSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLERE-IT 745
Query: 291 LLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILK 350
+ K + VD ++ +VE + + D + Q+ + +K +
Sbjct: 746 RYKDESSKAQAEVDRLL-EILKEVENEKNDK------DKKIAELERQVKDQNKKVANL-- 796
Query: 351 SHVEKLDNQVSKVHL-EGFNDEDVI--SRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQ 407
H E+++ + S L E ED + S Q + K + I++ +E ++ Q+ ++
Sbjct: 797 KHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAER 856
Query: 408 ---LATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLER 464
LA T + + LL E++K+E K + + ++ L ER
Sbjct: 857 EMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAER 916
Query: 465 KAFEEE 470
+ EE
Sbjct: 917 RKHLEE 922
Score = 33.9 bits (76), Expect = 0.45
Identities = 53/240 (22%), Positives = 102/240 (42%), Gaps = 20/240 (8%)
Query: 66 ISYLDQELTTFGFPSLYEESKGK-ETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQN 124
I +L++E+T + E SK + E R L I+ + NE +K + V+ QN
Sbjct: 737 IQHLEREITRYKD----ESSKAQAEVDRLLEILKEVE--NEKNDKDKKIAELERQVKDQN 790
Query: 125 LKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQ 184
K+ + Q K + LE +RR L + +QLQ R ++ ++ +++
Sbjct: 791 KKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESV 850
Query: 185 NIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRT 244
I A R + ++E ++++ +L+M +K+ ++ + + + S
Sbjct: 851 QITAEREMV----LAQEESARTNAEKQVEELLMAM--EKVKQELESMKAKLSSTQQSLAE 904
Query: 245 GKTEARN-EDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERV 303
+T N E K L E +Q+ +L +E + ++ LS KKK +E V
Sbjct: 905 KETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLE------LSSSKKKTQEEV 958
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 58.9 bits (141), Expect = 1e-08
Identities = 75/378 (19%), Positives = 179/378 (47%), Gaps = 58/378 (15%)
Query: 118 ENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQL-----QCKNR--NLH 170
+ ++ +N +L S ++ + Y + +L E+ L+++ L +CK + NL
Sbjct: 2280 DTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2339
Query: 171 QLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNK-LKERLHQLVMNKKDKKIAMDIL 229
+++ ++ ++Q ++++++ + + ++ L RLH+ + N K++KI
Sbjct: 2340 GIIRQQEADIQN---------SKFSYEQLETDLQASRELTSRLHEEI-NMKEQKI----- 2384
Query: 230 NYVGRADGKRGSWRTGKTEARNE-DEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEM 288
+ GK + + E R + D+ K L N +++ ++ E KK + + + M
Sbjct: 2385 --ISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLM 2442
Query: 289 ISLLSPQKKKPRERVD-DSTGTVISDVEED----AGELSRESMWDLSCETVREQL----- 338
+L + +K+ +++ DS +S ++ D G+ + LS ++QL
Sbjct: 2443 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAA 2502
Query: 339 --TNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDED----VISRQDHEQETEKLELEIQQ 392
N ++++ R L+SH++ L+++ +K+ E + VI+ +D +Q+ + LE+++QQ
Sbjct: 2503 AENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK-QLLEVQLQQ 2561
Query: 393 CKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRS 452
KE+ + + L+++L + E E L+ ++ +E+K++ +E S
Sbjct: 2562 NKEL-ENKYAKLEEKLKESE--------------EANEDLRRSFNALQEEKQDLSKEIES 2606
Query: 453 FTEAAIRLGLERKAFEEE 470
+ +L + A +EE
Sbjct: 2607 LKVSISQLTRQVTALQEE 2624
Score = 55.5 bits (132), Expect = 1e-07
Identities = 85/439 (19%), Positives = 191/439 (43%), Gaps = 47/439 (10%)
Query: 110 QRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQER----DRQLQCK 165
+ K+L ++N++ + L + HL+ +++ L +E+ LQE QL
Sbjct: 2131 EEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAF 2190
Query: 166 NRNLHQLLKNEK---DEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDK 222
+++ L + DE +K + + +++ KE + LK++L Q+ ++ ++
Sbjct: 2191 TKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2250
Query: 223 KIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQ 282
KI + R + + W +++A+ E ++ + + + + K++L + E + +
Sbjct: 2251 KI------NISRLEHDKQIW---ESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYH 2301
Query: 283 QMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELS---RESMWDL-SCETVREQL 338
+ E+ L S K + D S + +E G L R+ D+ + + EQL
Sbjct: 2302 SSQNELAKLESELKSLKDQLTDLSNS--LEKCKEQKGNLEGIIRQQEADIQNSKFSYEQL 2359
Query: 339 TNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVIS------RQDHEQETEKLELEIQQ 392
++ + E+++ + K+ E+ I RQ H++E ++LE + Q
Sbjct: 2360 ETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQ 2419
Query: 393 CKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSL--FKEQKKNFERER 450
+E + +L+++ A D T+ L + +KE ++++ L F + + + +R
Sbjct: 2420 EEE----ENIVLEEENKKAV--DKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDR 2473
Query: 451 -------RSFTEAAIRLGLERKAFEEERA---SWLKQQFLNMTT-FDHQNSENVKLFSAF 499
+ E + + LE+ +E A + LK++ + + D NSEN KL +
Sbjct: 2474 DRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAEL 2533
Query: 500 SGSSDWDNLIVHSRQPQKK 518
+ N ++ + Q+K
Sbjct: 2534 IQYREDLNQVITIKDSQQK 2552
Score = 53.1 bits (126), Expect = 7e-07
Identities = 79/404 (19%), Positives = 170/404 (42%), Gaps = 57/404 (14%)
Query: 45 LSKNVHSFFSAFCTEDNIEQSISYLDQELTTFGF------PSLYEESKGKETKRELNIVA 98
L ++ S T+D + L +E+T L +K KET E
Sbjct: 1866 LENEKNTLLSQISTKDG---ELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDL 1922
Query: 99 VLNCMNELLVLQRK-NLLAQENVETQ--NLKLGSDMDHLQSCYSKLKEQLETSRREMIGL 155
MN+L L Q+ + Q N L S+M +L+ C S+L+E+ + +E +
Sbjct: 1923 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKV 1982
Query: 156 QERDRQLQCKN--------------RNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRK 201
+ R+ + + L +LLK ++ EV++LQ +Y +
Sbjct: 1983 ESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK----DCIRYQEKISAL 2038
Query: 202 EREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLN 261
ER L + V + K + + N + ++ +A+ E +K+LL+
Sbjct: 2039 ERTVKAL-----EFVQTESQKDLEITKENLAQAVEHRK--------KAQAELASFKVLLD 2085
Query: 262 DYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISD---VEEDA 318
D + ++L +N +LKK LQ K+ + S + + + R++ + + + ++E
Sbjct: 2086 DTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKL 2145
Query: 319 GELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQD 378
L RE + E ++ ++ K+ + ++ E LD+ V++ L F + D
Sbjct: 2146 DALRREK---VHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQ--LAAFTKSMSSLQDD 2200
Query: 379 HEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRD 422
++ ++ + ++ + I+++++ ++ + +D S+L+D
Sbjct: 2201 RDRVIDEAKKWERKFSDAIQSKEEEIRLK------EDNCSVLKD 2238
Score = 50.4 bits (119), Expect = 5e-06
Identities = 71/399 (17%), Positives = 175/399 (43%), Gaps = 40/399 (10%)
Query: 85 SKGKETKRELNIVAVLNCMNELLVLQR-KNLLAQENVETQNLKLGSDMDHLQSCYSKLKE 143
++ KE L +A+L + L+ + ++LL +++ + L ++ L KL +
Sbjct: 1529 AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVK 1588
Query: 144 QLETSRREMIG----LQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIAS---------- 189
++E+ + I QE+ ++LQ + L Q +N +E +++Q+++ +
Sbjct: 1589 EIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYG 1648
Query: 190 --RATQYNH-----DMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRAD------ 236
R+T+ N ++ E+E ++KE++ + +K+ K + ++ N RA+
Sbjct: 1649 KLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGD 1708
Query: 237 -GKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQ---ILMENAELKKVLQQMKKEMISLL 292
K + A ++E+ ++ + +YE K+ ++ E L + +Q +K ++ +
Sbjct: 1709 TAKECMETLLSSNASMKEELERVKM-EYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNV 1767
Query: 293 SPQKK-KPRERVDDSTGTVISDVEEDAGELSRESMWDLSCE-TVREQLTNSIRKQWRILK 350
S Q + E+ D+ T + GE + +S T E + ++ + K
Sbjct: 1768 SKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSK 1827
Query: 351 --SHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQL 408
S ++++N + ++ E + ++ +Q+ ++ ++ K + +Q +L
Sbjct: 1828 DFSSHDEINNYLQQIDQ---LKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGEL 1884
Query: 409 ATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFE 447
++ T L + + EE R+ + +E+K + E
Sbjct: 1885 KMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1923
Score = 46.2 bits (108), Expect = 9e-05
Identities = 64/361 (17%), Positives = 155/361 (42%), Gaps = 57/361 (15%)
Query: 143 EQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKE 202
+Q++ + + GL+E + KN+ Q L+NEK N + S+ + + ++K +
Sbjct: 1840 QQIDQLKERIAGLEEEKQ----KNKEFSQTLENEK-------NTLLSQISTKDGELKMLQ 1888
Query: 203 REYNKL-------KERLHQLVMNKKDKKIAMD-----ILNYVGRADGKRGSWRTGKTEAR 250
E K+ +E L ++ K+ + D ++N + +G G++ T+A+
Sbjct: 1889 EEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQ 1948
Query: 251 NEDEMY-------KILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERV 303
++E+ K +++ E ++Q++ E KV +++KE + + +K+P +
Sbjct: 1949 IKNELLESEMKNLKKCVSELEEEKQQLVKEKT---KVESEIRKEYLEKIQGAQKEPGNKS 2005
Query: 304 D-DSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSI-------RKQWRILKSHVEK 355
++ + +++ +L ++ + + E+ ++ +K I K ++ +
Sbjct: 2006 HAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQ 2065
Query: 356 LDNQVSKVHLEGFNDEDVISRQDHEQ-----ETEKLELEIQQCKEMIKTQQQLLQQQLAT 410
K E + + ++ E + KL+ E+Q KE +K+Q + + L
Sbjct: 2066 AVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER 2125
Query: 411 AYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEE 470
+ L+ EK+ ++E+ + +K + E T I++ L +K E +
Sbjct: 2126 RLEQAEEKHLK------EKKNMQEKLDALRREKVHLEE-----TIGEIQVTLNKKDKEVQ 2174
Query: 471 R 471
+
Sbjct: 2175 Q 2175
Score = 44.7 bits (104), Expect = 3e-04
Identities = 87/409 (21%), Positives = 168/409 (41%), Gaps = 55/409 (13%)
Query: 59 EDNIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKN--LLA 116
ED +++ + +L + + E + E R+L + +LL++ ++N L A
Sbjct: 2677 EDKLKKELKHLHHDAGIMRNETETAEERVAELARDL-----VEMEQKLLMVTKENKGLTA 2731
Query: 117 Q-ENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQE-------RDRQLQCKNRN 168
Q ++ L + DH +LK + + S +E+ L+E RD L +
Sbjct: 2732 QIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFS 2791
Query: 169 LHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLK--ERLHQLVMNKKDKKIAM 226
++ +N ++KL + S+ Q H + E YN+++ + + N++D +
Sbjct: 2792 MNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERD-HLWN 2850
Query: 227 DILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKK 286
++ + +GK+ S T E + K ++ + + ++L E L++ Q+ +
Sbjct: 2851 ELEKFRKSEEGKQRSAAQPSTSPA-EVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQ 2909
Query: 287 EMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELS----------RESMWDLSCETVRE 336
E I+ L P K + +E D + I E LS +S W++ ++E
Sbjct: 2910 E-ITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKE 2968
Query: 337 QLTNSIRKQWRILKSHVEKL---------DNQVSKVHLEGFNDEDVISRQDHEQ----ET 383
Q +I + + L SH++ L Q KV + + + D Q ET
Sbjct: 2969 QYLMAISDKDQQL-SHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYET 3027
Query: 384 EKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERL 432
E L ++ + I Q++L QQL + + LLEEK L
Sbjct: 3028 ELLRTQLNDSLKEIH-QKELRIQQLNSNFSQ----------LLEEKNTL 3065
Score = 37.4 bits (85), Expect = 0.041
Identities = 79/372 (21%), Positives = 156/372 (41%), Gaps = 49/372 (13%)
Query: 120 VETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDE 179
+E + L L + + LQ KL+E L TSR+ ++ ++ Q K R+L + LK +KD+
Sbjct: 1162 LEEKILALEKEKEQLQK---KLQEAL-TSRKAIL------KKAQEKERHLREELKQQKDD 1211
Query: 180 VQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKR 239
+LQ Q++ K E ++L++ Q+ + K + D G
Sbjct: 1212 YNRLQE-------QFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLE 1264
Query: 240 GSWRTGKTEARNEDEMYKILLNDYEYRQK-----QILMENAELKKVLQQMKKEMISLLSP 294
+ + + L D+ + Q A++K L++++ E + L
Sbjct: 1265 EPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELK 1324
Query: 295 QKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLS------CETVREQLTNSI-----R 343
E S + + L ES+ +S E+++++L +S
Sbjct: 1325 VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL 1384
Query: 344 KQWRILKSHVEKLDNQVSKVHLEGFNDEDV--ISRQDHEQET--EKLELEIQQCKEMIKT 399
+ R L+ +++L +SK +EDV +S Q E+E K++ EI + +++IK
Sbjct: 1385 EHLRELQPKLDELQKLISK------KEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKA 1438
Query: 400 QQQLLQQQLATAYDDDTTSL-LRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAI 458
L+ Q A +D+ L + C + ++ E + EE K+ +R+ ++ +
Sbjct: 1439 LHTQLEMQ-AKEHDERIKQLQVELCEMKQKPEEIGEE----SRAKQQIQRKLQAALISRK 1493
Query: 459 RLGLERKAFEEE 470
E K+ +EE
Sbjct: 1494 EALKENKSLQEE 1505
Score = 33.5 bits (75), Expect = 0.59
Identities = 35/169 (20%), Positives = 73/169 (43%), Gaps = 17/169 (10%)
Query: 328 DLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFN-------DEDVISRQD-- 378
D + + R+ N I+K K+ + L+ + ++ +G E+ +S+ D
Sbjct: 79 DEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKS 138
Query: 379 ---HEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEE 435
E E EK++ ++Q+ +E+I T Q L Q A +T + + ++ + +E
Sbjct: 139 STEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEF 198
Query: 436 WSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFLNMTT 484
S + Q + E +AA ++ E+ A E + + + L + T
Sbjct: 199 ISTLQAQLSQTQAE-----QAAQQVVREKDARFETQVRLHEDELLQLVT 242
Score = 30.4 bits (67), Expect = 5.0
Identities = 54/277 (19%), Positives = 112/277 (40%), Gaps = 33/277 (11%)
Query: 114 LLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIG-------LQERDRQLQCKN 166
L+ Q +VET+ +Q L+ +LE ++G LQ+ + +N
Sbjct: 240 LVTQADVETE----------MQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRN 289
Query: 167 RNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAM 226
+ L Q L+ + E L+N + + + +++ E E + K H L +++ +
Sbjct: 290 QILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNL---QEEMHHLL 346
Query: 227 DILNYVGRADGK---RGSWRTGKTEARNEDEMYKILLNDYEYRQKQILME--NAELKKVL 281
+ G+A + R S K +A E++ IL ++ Q + + K+L
Sbjct: 347 EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLL 406
Query: 282 QQMKK------EMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVR 335
Q + + I L Q ++ + + + E A + S +++ + V
Sbjct: 407 QDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVT 466
Query: 336 EQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDED 372
E+ S++K R+++ EK +S + LE E+
Sbjct: 467 EENIASLQK--RVVELENEKGALLLSSIELEELKAEN 501
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 58.5 bits (140), Expect = 2e-08
Identities = 75/346 (21%), Positives = 147/346 (42%), Gaps = 45/346 (13%)
Query: 142 KEQLETSRREMIGLQERDRQLQ----CKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHD 197
+EQ E R L++RDRQ + + R Q + + E ++LQ+ ++ +
Sbjct: 152 EEQSEKQER----LEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207
Query: 198 MKRKEREYNKLK----ERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNED 253
+ + RE +L+ E Q ++D+ + + WR +T R E+
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEE----------EEKEWRKRETVLRKEE 257
Query: 254 EMYKILLNDYEYRQKQILMENAELKKV-LQQMKKEMISLLSPQKKKPRERVDDSTGTVIS 312
E L + RQ+++ E +L+K+ Q++++E Q++ RE+ +
Sbjct: 258 EK---LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ------QLRR 308
Query: 313 DVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDED 372
EE+ E E +E+ R++ ++ + E+ + Q+ + E ++
Sbjct: 309 KQEEERREQQEERREQQERREQQEE-----RREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 373 VISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERL 432
+ EQE E+ E ++++ +++ + QQ +QQL LR L +++L
Sbjct: 364 L----RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 433 KEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQ 478
+ E L +EQ E ER R K +EER WLK++
Sbjct: 420 RREQQLRREQ----EEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Score = 55.1 bits (131), Expect = 2e-07
Identities = 79/345 (22%), Positives = 150/345 (43%), Gaps = 60/345 (17%)
Query: 141 LKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKD--EVQKLQNIIASRATQYNHDM 198
L+EQL R+E LQE + +LQ + R + + E+ E ++LQ Q +
Sbjct: 895 LQEQL---RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ--------QEEEQL 943
Query: 199 KRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNED---EM 255
R+ERE + +ER Q +KDKK+ +G KR K E+ E
Sbjct: 944 LREEREKRRRQERERQY---RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
Query: 256 YKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVE 315
++L + E R++Q K LQQ +++ LL +++K R + + +++
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQ---LLREEREKRRLQERERQYREEEELQ 1057
Query: 316 EDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVIS 375
++ +L E ET R Q + +Q+R E+L + +E ++
Sbjct: 1058 QEEEQLLGEER-----ETRRRQ---ELERQYR----KEEELQQE----------EEQLLR 1095
Query: 376 RQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEE 435
+ ++ ++ E + ++ +E+ + ++QLL+++ + R EE+E +EE
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR-----EEEEVQQEE 1150
Query: 436 WSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFL 480
L +E+ + R+ LER+ EEE ++Q L
Sbjct: 1151 EQLLREEPEKRRRQE-----------LERQYREEEELQQEEEQLL 1184
Score = 53.1 bits (126), Expect = 7e-07
Identities = 72/344 (20%), Positives = 151/344 (43%), Gaps = 41/344 (11%)
Query: 140 KLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMK 199
+L+ + E R + + QE + +LQ + R+ QL + +++ ++L + + +
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
Query: 200 RKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKIL 259
R +RE + +++L + ++ +++ + + + KR + E R E + +
Sbjct: 566 RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL-KREEVERLEQEERREQRLKRE- 623
Query: 260 LNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAG 319
E R++Q+L + ++ QQ+++E ++++ R + ++ + ++ +
Sbjct: 624 -EPEEERRQQLLKSEEQEERRQQQLRREQ-----QERREQRLKREEEEERLEQRLKREHE 677
Query: 320 ELSRES-MWDLSCETVREQLTNSIRK-QWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQ 377
E RE + + E RE++ + I K QW++ + D + SKV+ E RQ
Sbjct: 678 EERREQELAEEEQEQARERIKSRIPKWQWQL----ESEADARQSKVYSRPRKQEGQRRRQ 733
Query: 378 DHEQETEKLELEIQ-QCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEW 436
+ E++ + E E+Q Q +E QQQ EE++R W
Sbjct: 734 EQEEKRRRRESELQWQEEERAHRQQQ------------------------EEEQRRDFTW 769
Query: 437 SLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFL 480
E+K R+R S +R ER+ EER +Q+FL
Sbjct: 770 QWQAEEKSERGRQRLS-ARPPLREQRERQLRAEERQQ-REQRFL 811
Score = 50.8 bits (120), Expect = 4e-06
Identities = 68/340 (20%), Positives = 152/340 (44%), Gaps = 55/340 (16%)
Query: 140 KLKEQLETSRREM-IGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDM 198
+LK E RRE + L+E +R+ Q + R Q L+ E++E ++ Q + +
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERRE--QQLRREQEE-RREQRLKRQEEEERLQQR 531
Query: 199 KRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKI 258
R E++ + +E + ++ ++++K R + +R R + + D++ K
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEK----------RLEQERREQRLKREQEERRDQLLK- 580
Query: 259 LLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDA 318
+ E RQ+++ E E ++ Q++K+E + L Q+++ +R+ E+
Sbjct: 581 --REEERRQQRLKREQEE--RLEQRLKREEVERLE-QEERREQRLK----------REEP 625
Query: 319 GELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQD 378
E R+ + L E E R+Q ++ + E+ + ++ +
Sbjct: 626 EEERRQQL--LKSEEQEE------RRQQQLRREQQERREQRLKR---------------- 661
Query: 379 HEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSL 438
E+E E+LE +++ E + +Q+L +++ A + + + + + LE + ++
Sbjct: 662 -EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
Query: 439 FKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQ 478
+ +K+ +R R+ E R E + EEERA +Q+
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQE 760
Score = 48.1 bits (113), Expect = 2e-05
Identities = 76/368 (20%), Positives = 158/368 (42%), Gaps = 51/368 (13%)
Query: 110 QRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRRE--MIGLQERDRQLQCKNR 167
++K+ L QE E Q L+ + LQ + +E+ E + E ++G + R+ Q R
Sbjct: 1021 RKKDELQQE--EEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 168 NLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMD 227
+ + +++E Q L+ R Q + +R+ RE +L++ QL+ +++K+ +
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQ---ERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Query: 228 ILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKE 287
+ R + E + E ++L + E R++Q L ++ LQQ +++
Sbjct: 1136 LE-------------RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Query: 288 MISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWR 347
++ ++++ RER EE+ R+ + E + ++ QW
Sbjct: 1183 LLREEQEKRRQERERQYRE--------EEELQRQKRKQRYR------DEDQRSDLKWQWE 1228
Query: 348 ILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQ 407
K + + DN KV+ +G +E +D + + + ++Q ++ QQ+ ++Q
Sbjct: 1229 PEKENAVR-DN---KVYCKGRENEQFRQLEDSQLRDRQSQQDLQ---HLLGEQQERDREQ 1281
Query: 408 LATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERE----RRSFTEAAIRLGLE 463
+ RD + EE++ +EE K + + + E R E R +
Sbjct: 1282 ERRRWQQ------RDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETD 1335
Query: 464 RKAFEEER 471
RK EEE+
Sbjct: 1336 RKFREEEQ 1343
Score = 48.1 bits (113), Expect = 2e-05
Identities = 72/372 (19%), Positives = 153/372 (41%), Gaps = 33/372 (8%)
Query: 110 QRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREM-IGLQERDRQLQCKNRN 168
QR+ QE + + + G + + +EQL R E + QERDR+ + + +
Sbjct: 1528 QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQK 1587
Query: 169 LHQLLKNEK--DEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAM 226
+ + + K ++ Q+L+ + + D K +E E + QL ++D+K
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 227 DILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKK 286
+ R + R + E+E LL + E +Q + + + ++ QQ+++
Sbjct: 1648 EEPQL--RRQEREQQLRHDRDRKFREEEQ---LLQEGEEQQLRRQERDRKFREEEQQLRR 1702
Query: 287 EMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQW 346
+ ++ R+ + + ++E E + L ET +EQL R +
Sbjct: 1703 Q---------ERERKFLQEEQQLRRQELERKFREEEQ-----LRQETEQEQLRRQERYR- 1747
Query: 347 RILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQ 406
+IL+ + + + ++ + D + QE E+ +L Q+ + ++QL Q+
Sbjct: 1748 KILEEEQLRPEREEQQLRRQE-RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE 1806
Query: 407 QLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKA 466
+ + RD K R +EE +EQ++ +ER A + + K+
Sbjct: 1807 R----EEQQLRPQQRD-----GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS 1857
Query: 467 FEEERASWLKQQ 478
EE+ W +++
Sbjct: 1858 RREEQELWQEEE 1869
Score = 45.1 bits (105), Expect = 2e-04
Identities = 79/362 (21%), Positives = 155/362 (42%), Gaps = 51/362 (14%)
Query: 138 YSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK--DEVQKLQNIIASRATQYN 195
+ K ++QL RE Q+RDR+ + + + L + ++ K +E Q+++ R
Sbjct: 1392 FLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEE 1451
Query: 196 HDMKRKER------EYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEA 249
R+ER E L+ER Q + ++ + ++ + R + R + + E
Sbjct: 1452 EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR---KFREQEL 1508
Query: 250 RNEDEMYKILLNDY----EYRQKQILMENAELKKVL--QQMKKEMISLLSPQKKKPRERV 303
R+++ K L + + RQ++ L E +L++ QQ +++ +++ +ER
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER- 1567
Query: 304 DDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKV 363
E+ R+ + L + VR Q +Q R ++L Q +
Sbjct: 1568 ----------EEQQLSRQERDRKFRLEEQKVRRQ------EQERKFMEDEQQLRRQEGQQ 1611
Query: 364 HL-----EGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTS 418
L F +++ + ++ EQ+ + E + + +E + ++Q +QQL D
Sbjct: 1612 QLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR---HDRDRK 1668
Query: 419 LLRDCYLLEEKE----RLKEEWSLFKEQKKNF---ERERRSFTE--AAIRLGLERKAFEE 469
+ LL+E E R +E F+E+++ ERER+ E R LERK EE
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728
Query: 470 ER 471
E+
Sbjct: 1729 EQ 1730
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 57.8 bits (138), Expect = 3e-08
Identities = 91/421 (21%), Positives = 185/421 (43%), Gaps = 77/421 (18%)
Query: 108 VLQRKNLLAQENVETQNLKLGSDMD--------HLQSCYSKLKEQLETSRREMIGL---- 155
V+ RK ++ Q+ + N K SD++ +L +KL+ + E ++M +
Sbjct: 142 VMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNA 201
Query: 156 ---QERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKER- 211
RD Q+ + + + + L E+ + ++ + ++ Q +++RK RE R
Sbjct: 202 KCHAIRDAQI-LEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQ 260
Query: 212 -LHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQI 270
+ Q+ N++++ + + + + ++ + + ED L D E RQ+Q
Sbjct: 261 IVEQMEKNQEERSLLAE------QREQEKEQMLEYMEQLQEED------LKDMERRQQQK 308
Query: 271 LMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLS 330
L AE+K++ + +K+ LL+ Q+K + V +E +++RE+ ++
Sbjct: 309 LKMQAEIKRINDENQKQKAELLA-QEKLADQMV----------MEFTKKKMAREAEFEAE 357
Query: 331 CETVREQLTNSIRKQWRILKSHVEKL-DNQVSKVHLEGFNDEDVISRQDHEQETEKLELE 389
E +R + I + L++ EK D Q + L +++V R+ +E E +
Sbjct: 358 QERIRREKEKEIAR----LRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKK 413
Query: 390 IQQCKEMIKTQ-QQLLQQQLATAYD-----DDTTSLLRDCYLLEEKERLKEEW------- 436
++ E+ K++ +Q+ ++ A A D+ +LR EKERL+EE
Sbjct: 414 METEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQ 473
Query: 437 ---SLFKEQKKN-----------FERERRSFTEAAIRL----GLERKAFEEERASWLKQQ 478
L ++ ++N FE RR EA R ++RK EE RA+ L ++
Sbjct: 474 HANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERIDEIKRKKLEELRATGLPEK 533
Query: 479 F 479
+
Sbjct: 534 Y 534
Score = 30.0 bits (66), Expect = 6.5
Identities = 45/260 (17%), Positives = 108/260 (41%), Gaps = 11/260 (4%)
Query: 246 KTEARNEDEMYKILLNDYEYRQKQILMENAELK-KVLQQMKKEMISLLSPQKKKPRERVD 304
K+ A+ + + +LL D QK + + K + +Q + ++M+ L + P
Sbjct: 43 KSPAQGQSDSPIVLLRDKHTLQKTLTALGLDRKPETIQLITRDMVRELIVPTEDPSGESL 102
Query: 305 DSTGTVISDVEEDAGELSRESMW--DLSCETVREQLTNSIRKQWRILK------SHVEKL 356
+ ++ + L+RE + D + + +E +++ + +I+K ++ +KL
Sbjct: 103 IISPEEFERIKWASHVLTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKL 162
Query: 357 DN--QVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDD 414
+ +V+K + R + E+E + + I K Q+L++Q D
Sbjct: 163 SDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELD 222
Query: 415 DTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASW 474
L +E ++ ++ + L +++++ R RR E + ER E+R
Sbjct: 223 TEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQE 282
Query: 475 LKQQFLNMTTFDHQNSENVK 494
+Q M ++ ++++
Sbjct: 283 KEQMLEYMEQLQEEDLKDME 302
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 57.4 bits (137), Expect = 4e-08
Identities = 84/398 (21%), Positives = 158/398 (39%), Gaps = 84/398 (21%)
Query: 103 MNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQL 162
M E L++ +EN E Q L + +HL S L++ R I + R + +
Sbjct: 532 MKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ------RSQISAEARVKDI 585
Query: 163 QCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDK 222
+ +N+ LH+ +K ++ K++ + H ++ ER +L+ LH L K+++
Sbjct: 586 EKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERA-EELENELHHL--EKENE 642
Query: 223 KIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQ 282
+ I N + K EA E ++ EN +LKK L
Sbjct: 643 LLQKKITNLKITCE---------KIEA-------------LEQENSELERENRKLKKTLD 680
Query: 283 QMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSR--ESMWDLSCETVREQLTN 340
K L S +K+ S ++E+ EL R ES+ S + + QL N
Sbjct: 681 SFKNLTFQLESLEKEN-------------SQLDEENLELRRNVESLKCASMKMAQLQLEN 727
Query: 341 S--------IRKQWRILKSHVEKLDN-QVSKVHLEGFNDEDVISRQDHEQETEKLELEIQ 391
++K +LK+ +K + +VS L+ N + ++ ++ ++LE E+Q
Sbjct: 728 KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ 787
Query: 392 QCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERR 451
++ + Q LQ+ L EE + ++ + E+E +
Sbjct: 788 D----LEMENQTLQKNL-------------------------EELKISSKRLEQLEKENK 818
Query: 452 SFTEAAIRLGLERKAFEEERASWLKQQFLNMTTFDHQN 489
S + +L ++K E+E +Q + TT + N
Sbjct: 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Score = 50.8 bits (120), Expect = 4e-06
Identities = 141/666 (21%), Positives = 249/666 (37%), Gaps = 147/666 (22%)
Query: 25 ETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTEDNIEQS--ISYLDQELTTFGFPSLY 82
E ++ S+ Y+QQ+ + KN + E ++ S IS D +
Sbjct: 980 EARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKW--------- 1030
Query: 83 EESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQ----------ENVETQNLKLGSDMD 132
E + +ET REL L + L+ ++R N Q + +ETQN
Sbjct: 1031 -ERESQETTREL-----LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN-------- 1076
Query: 133 HLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNL---HQLLKNEKDEV--QKLQNII 187
+ L+ Q+ +R+ + LQE++ LQ +N L + L ++ + Q Q +I
Sbjct: 1077 ------NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLI 1130
Query: 188 ASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKT 247
+ + ++ KERE LK L+ K +K+ + + T K+
Sbjct: 1131 QQSSLENENESVIKERE--DLKSLYDSLI--KDHEKLELLHERQASEYESLISKHGTLKS 1186
Query: 248 EARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDST 307
+N + ++ D E R Q+L + +L+ + + +K E +L K
Sbjct: 1187 AHKNLEVEHR----DLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHE-------- 1234
Query: 308 GTVISDVEEDAGE-----------LSRESMWDLSCETVREQLTNSIRKQWRI------LK 350
TV ++ ++ GE L + + ++ L NS +Q R+ LK
Sbjct: 1235 -TVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLK 1293
Query: 351 SHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLAT 410
++LD +K++ N +++S+ E E L + Q + ++ + LL+Q + +
Sbjct: 1294 EQYQQLDITSTKLN----NQCELLSQLKGNLEEENRHL-LDQIQTLMLQNRTLLEQNMES 1348
Query: 411 ---------AYDDDTTSLLRDCYLLEEK------------ERLKEEWSLFK-----EQKK 444
Y D L R LEEK R + W K + KK
Sbjct: 1349 KDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKK 1408
Query: 445 NFERER-RSFTEAAIRLGLERKAFEEERASWLKQQFLNMTTFDHQNSENVKLFSAFSG-- 501
+ RER +S T R S + FL + D Q+S +V S G
Sbjct: 1409 DINRERQKSLTLTPTR-------------SDSSEGFLQLPHQDSQDSSSVGSNSLEDGQT 1455
Query: 502 -----SSDWDNLI---------VHSRQPQKKPHSVSNGSPVCMSKLTKSLPASPSTSDFC 547
SS ++L+ S + + P +S G K ++ S + +F
Sbjct: 1456 LGTKKSSTMNDLVQSMVLAGQWTGSTENLEVPDDISTGK---RRKELGAMAFSTTAINFS 1512
Query: 548 QTRSCISEHSSINVLN---ITAEEIKPNQVGGERTNQKWSVASRPGSQEGCYSGCSLSYT 604
S S V N + E+I P V + + ASRP S + + S S
Sbjct: 1513 TVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNN 1572
Query: 605 NSHVEK 610
N+ + +
Sbjct: 1573 NASLHE 1578
Score = 43.5 bits (101), Expect = 6e-04
Identities = 82/421 (19%), Positives = 175/421 (41%), Gaps = 58/421 (13%)
Query: 126 KLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQN 185
+L D L + L++QLE +R L E +++ LH + + +K++
Sbjct: 348 ELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEE 407
Query: 186 IIASRATQYNHDMKRKEREYNKLKERLH---QLVMNKKDKKIAMDILNYVGRADGKRGSW 242
++ T +M +K+ + E LH +L + +++ +G + S
Sbjct: 408 LMEENMTL---EMAQKQ----SMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSS 460
Query: 243 RTGKTEARNED-----EMYKILLNDYEYRQKQIL---MENAELKKVLQQMKKEMI----- 289
R K E N+ E + ++ E +IL EN L K ++ ++ E++
Sbjct: 461 RLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQS 520
Query: 290 ----SLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRES---MWDLSCETVREQLT--- 339
LS K + +++ + T+ + E L +E+ +S R Q++
Sbjct: 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Query: 340 --NSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMI 397
I K+ +IL +++ +++SK+ F + +H +E + E++ +
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIE---FEKRQIKKELEHYKEKGERAEELENELHHL 637
Query: 398 KTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAA 457
+ + +LLQ+++ T+L C E+ E L++E S + + + ++ SF
Sbjct: 638 EKENELLQKKI--------TNLKITC---EKIEALEQENSELERENRKLKKTLDSFKNLT 686
Query: 458 IRLGLERKAFEEERASWLKQQFLNMTTFDHQNSENVKLFSAFSGSSDWDNLIVHSRQPQK 517
+L ++ E+E S L ++ L + +N E++K S +N + S + Q
Sbjct: 687 FQL----ESLEKEN-SQLDEENLEL----RRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 518 K 518
K
Sbjct: 738 K 738
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 57.4 bits (137), Expect = 4e-08
Identities = 84/398 (21%), Positives = 158/398 (39%), Gaps = 84/398 (21%)
Query: 103 MNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQL 162
M E L++ +EN E Q L + +HL S L++ R I + R + +
Sbjct: 532 MKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ------RSQISAEARVKDI 585
Query: 163 QCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDK 222
+ +N+ LH+ +K ++ K++ + H ++ ER +L+ LH L K+++
Sbjct: 586 EKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERA-EELENELHHL--EKENE 642
Query: 223 KIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQ 282
+ I N + K EA E ++ EN +LKK L
Sbjct: 643 LLQKKITNLKITCE---------KIEA-------------LEQENSELERENRKLKKTLD 680
Query: 283 QMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSR--ESMWDLSCETVREQLTN 340
K L S +K+ S ++E+ EL R ES+ S + + QL N
Sbjct: 681 SFKNLTFQLESLEKEN-------------SQLDEENLELRRNVESLKCASMKMAQLQLEN 727
Query: 341 S--------IRKQWRILKSHVEKLDN-QVSKVHLEGFNDEDVISRQDHEQETEKLELEIQ 391
++K +LK+ +K + +VS L+ N + ++ ++ ++LE E+Q
Sbjct: 728 KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ 787
Query: 392 QCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERR 451
++ + Q LQ+ L EE + ++ + E+E +
Sbjct: 788 D----LEMENQTLQKNL-------------------------EELKISSKRLEQLEKENK 818
Query: 452 SFTEAAIRLGLERKAFEEERASWLKQQFLNMTTFDHQN 489
S + +L ++K E+E +Q + TT + N
Sbjct: 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Score = 47.0 bits (110), Expect = 5e-05
Identities = 103/487 (21%), Positives = 188/487 (38%), Gaps = 111/487 (22%)
Query: 25 ETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTEDNIEQS--ISYLDQELTTFGFPSLY 82
E ++ S+ Y+QQ+ + KN + E ++ S IS D +
Sbjct: 979 EARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKW--------- 1029
Query: 83 EESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQ----------ENVETQNLKLGSDMD 132
E + +ET REL L + L+ ++R N Q + +ETQN
Sbjct: 1030 -ERESQETTREL-----LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN-------- 1075
Query: 133 HLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNL---HQLLKNEKDEV--QKLQNII 187
+ L+ Q+ +R+ + LQE++ LQ +N L + L ++ + Q Q +I
Sbjct: 1076 ------NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLI 1129
Query: 188 ASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKT 247
+ + ++ KERE LK L+ K +K+ + + T K+
Sbjct: 1130 QQSSLENENESVIKERE--DLKSLYDSLI--KDHEKLELLHERQASEYESLISKHGTLKS 1185
Query: 248 EARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDST 307
+N + ++ D E R Q+L + +L+ + + +K E +L K
Sbjct: 1186 AHKNLEVEHR----DLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHE-------- 1233
Query: 308 GTVISDVEEDAGE-----------LSRESMWDLSCETVREQLTNSIRKQWRI------LK 350
TV ++ ++ GE L + + ++ L NS +Q R+ LK
Sbjct: 1234 -TVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLK 1292
Query: 351 SHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLAT 410
++LD +K++ N +++S+ E E L + Q + ++ + LL+Q + +
Sbjct: 1293 EQYQQLDITSTKLN----NQCELLSQLKGNLEEENRHL-LDQIQTLMLQNRTLLEQNMES 1347
Query: 411 ---------AYDDDTTSLLRDCYLLEEK------------ERLKEEWSLFK-----EQKK 444
Y D L R LEEK R + W K + KK
Sbjct: 1348 KDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKK 1407
Query: 445 NFERERR 451
+ RER+
Sbjct: 1408 DINRERQ 1414
Score = 43.5 bits (101), Expect = 6e-04
Identities = 82/421 (19%), Positives = 175/421 (41%), Gaps = 58/421 (13%)
Query: 126 KLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQN 185
+L D L + L++QLE +R L E +++ LH + + +K++
Sbjct: 348 ELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEE 407
Query: 186 IIASRATQYNHDMKRKEREYNKLKERLH---QLVMNKKDKKIAMDILNYVGRADGKRGSW 242
++ T +M +K+ + E LH +L + +++ +G + S
Sbjct: 408 LMEENMTL---EMAQKQ----SMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSS 460
Query: 243 RTGKTEARNED-----EMYKILLNDYEYRQKQIL---MENAELKKVLQQMKKEMI----- 289
R K E N+ E + ++ E +IL EN L K ++ ++ E++
Sbjct: 461 RLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQS 520
Query: 290 ----SLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRES---MWDLSCETVREQLT--- 339
LS K + +++ + T+ + E L +E+ +S R Q++
Sbjct: 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Query: 340 --NSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMI 397
I K+ +IL +++ +++SK+ F + +H +E + E++ +
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIE---FEKRQIKKELEHYKEKGERAEELENELHHL 637
Query: 398 KTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAA 457
+ + +LLQ+++ T+L C E+ E L++E S + + + ++ SF
Sbjct: 638 EKENELLQKKI--------TNLKITC---EKIEALEQENSELERENRKLKKTLDSFKNLT 686
Query: 458 IRLGLERKAFEEERASWLKQQFLNMTTFDHQNSENVKLFSAFSGSSDWDNLIVHSRQPQK 517
+L ++ E+E S L ++ L + +N E++K S +N + S + Q
Sbjct: 687 FQL----ESLEKEN-SQLDEENLEL----RRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 518 K 518
K
Sbjct: 738 K 738
Score = 42.0 bits (97), Expect = 0.002
Identities = 91/449 (20%), Positives = 174/449 (38%), Gaps = 47/449 (10%)
Query: 85 SKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQS-CYSKLKE 143
S+ +T++ N + L E + L ++ LL E KL L+S S LK+
Sbjct: 913 SEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKL------LESKLESTLKK 966
Query: 144 QLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKL-QNIIASRATQYNHDMKRKE 202
LE ++ L+ R + N+ L Q LK K + L Q R Q + + ++
Sbjct: 967 SLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGED 1026
Query: 203 REYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILL-- 260
++ + + + ++ KD+ I ++ N +A+ + + + E +N + +IL
Sbjct: 1027 NKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQ 1086
Query: 261 ----------NDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKK---------KPRE 301
+ + ++ +EN+ L + + LL Q K RE
Sbjct: 1087 RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERE 1146
Query: 302 RVDDSTGTVISDVEE-----DAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKL 356
+ ++I D E+ + ES+ +S + ++ + R L+ +L
Sbjct: 1147 DLKSLYDSLIKDHEKLELLHERQASEYESL--ISKHGTLKSAHKNLEVEHRDLEDRYNQL 1204
Query: 357 DNQVSKVH-----LEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATA 411
Q ++ L+ ++ ++ ++HE + + + + T QLL++
Sbjct: 1205 LKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQ 1264
Query: 412 YDD-DTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEE 470
D + SLL + L E+ RL+ E+S KEQ + + L + EEE
Sbjct: 1265 TDHKNLKSLLNNSKL--EQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEE 1322
Query: 471 RASWLKQ---QFLNMTTFDHQNSENVKLF 496
L Q L T QN E+ LF
Sbjct: 1323 NRHLLDQIQTLMLQNRTLLEQNMESKDLF 1351
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 57.0 bits (136), Expect = 5e-08
Identities = 71/364 (19%), Positives = 150/364 (41%), Gaps = 63/364 (17%)
Query: 123 QNLKLGSDMDHLQSCYSKLKEQLETSRREMI-----------GLQERD------------ 159
+ L+ +M LQ+ Y LK+Q+E E++ G + D
Sbjct: 1318 ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYER 1377
Query: 160 --RQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVM 217
R++ + L Q +++ + Q+ + + R D + +R +LK++ +L
Sbjct: 1378 AVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
Query: 218 NKKDKKIAMD---ILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMEN 274
+D K+ ++ + N+ + K+ + + ++A E + K+ + + +L E
Sbjct: 1438 ELQDTKLHLEGQQVRNH--ELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEA 1495
Query: 275 AELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETV 334
LK+ L++ ++ T V+S E S+ES + S V
Sbjct: 1496 FSLKQQLEEKDMDIAGF---------------TQKVVSLEAELQDISSQESKDEASLAKV 1540
Query: 335 REQLTNSIRKQWRILKSHVEKLDNQVSKVHLEG-----FNDEDVISRQDHEQETEKLELE 389
++QL + K +K E+LD Q + + E RQ H +E E + E
Sbjct: 1541 KKQLRDLEAK----VKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEE 1596
Query: 390 IQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQ--KKNFE 447
+++ ++ + + + ++ QL Y+D +L EK L+ + + +Q +++FE
Sbjct: 1597 VEEARQSCQKKLKQMEVQLEEEYEDKQK-------VLREKRELEGKLATLSDQVNRRDFE 1649
Query: 448 RERR 451
E+R
Sbjct: 1650 SEKR 1653
Score = 40.8 bits (94), Expect = 0.004
Identities = 56/281 (19%), Positives = 112/281 (39%), Gaps = 29/281 (10%)
Query: 198 MKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYK 257
++ K+ E +L+ +L + + + ++ D R + + + T+ RN E
Sbjct: 1256 IRNKDEEIQQLRSKLEKAEKERNELRLNSD------RLESRISELTSELTDERNTGESAS 1309
Query: 258 ILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEED 317
LL+ + + E EL+ +KK+M + + R + G V D D
Sbjct: 1310 QLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD---D 1366
Query: 318 AGELSRESMWDLSCE-TVRE------QLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFND 370
AG W L E VRE +L + + + + +L+ ++ + +
Sbjct: 1367 AG-----GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
Query: 371 EDVIS-------RQDHEQETEKLELEIQQCKEM-IKTQQQLLQQQLATAYDDDTTSLLRD 422
+ + R E + KL LE QQ + ++ +Q+ +L+ A+++ L+
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
Query: 423 CYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLE 463
L EK+ L E K+Q + + + FT+ + L E
Sbjct: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAE 1522
Score = 39.7 bits (91), Expect = 0.008
Identities = 53/279 (18%), Positives = 117/279 (41%), Gaps = 18/279 (6%)
Query: 120 VETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDE 179
VE ++L L +D + + L+EQL +RE +Q R L+ ++++L+K K
Sbjct: 1711 VEIEDLHL--QIDDIAKAKTALEEQLSRLQREKNEIQNR---LEEDQEDMNELMKKHKAA 1765
Query: 180 VQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKR 239
V + +A + ++ +E +L+E+L L + + +M + V R + K
Sbjct: 1766 VAQASRDLA-QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKI 1824
Query: 240 GSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKP 299
T R + + + L + + ++ L E + + + +KE L Q +
Sbjct: 1825 RELETRLEFERTQVKRLESLASRLKENMEK-LTEERDQRIAAENREKEQNKRLQRQLRDT 1883
Query: 300 RERVDDSTGTVISDVEEDAGELSRESMWDL-SCETVREQLTNSIRKQWRILKSHVEKLDN 358
+E + + ++ E +A E DL S E + L ++ ++ + +++
Sbjct: 1884 KEEMGE-----LARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED 1938
Query: 359 QVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMI 397
+ +E +ED+I+ + +LE + K +
Sbjct: 1939 E-----MESDENEDLINSEGDSDVDSELEDRVDGVKSWL 1972
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 57.0 bits (136), Expect = 5e-08
Identities = 71/364 (19%), Positives = 150/364 (41%), Gaps = 63/364 (17%)
Query: 123 QNLKLGSDMDHLQSCYSKLKEQLETSRREMI-----------GLQERD------------ 159
+ L+ +M LQ+ Y LK+Q+E E++ G + D
Sbjct: 1318 ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYER 1377
Query: 160 --RQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVM 217
R++ + L Q +++ + Q+ + + R D + +R +LK++ +L
Sbjct: 1378 AVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
Query: 218 NKKDKKIAMD---ILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMEN 274
+D K+ ++ + N+ + K+ + + ++A E + K+ + + +L E
Sbjct: 1438 ELQDTKLHLEGQQVRNH--ELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEA 1495
Query: 275 AELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETV 334
LK+ L++ ++ T V+S E S+ES + S V
Sbjct: 1496 FSLKQQLEEKDMDIAGF---------------TQKVVSLEAELQDISSQESKDEASLAKV 1540
Query: 335 REQLTNSIRKQWRILKSHVEKLDNQVSKVHLEG-----FNDEDVISRQDHEQETEKLELE 389
++QL + K +K E+LD Q + + E RQ H +E E + E
Sbjct: 1541 KKQLRDLEAK----VKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEE 1596
Query: 390 IQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQ--KKNFE 447
+++ ++ + + + ++ QL Y+D +L EK L+ + + +Q +++FE
Sbjct: 1597 VEEARQSCQKKLKQMEVQLEEEYEDKQK-------VLREKRELEGKLATLSDQVNRRDFE 1649
Query: 448 RERR 451
E+R
Sbjct: 1650 SEKR 1653
Score = 40.8 bits (94), Expect = 0.004
Identities = 56/281 (19%), Positives = 112/281 (39%), Gaps = 29/281 (10%)
Query: 198 MKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYK 257
++ K+ E +L+ +L + + + ++ D R + + + T+ RN E
Sbjct: 1256 IRNKDEEIQQLRSKLEKAEKERNELRLNSD------RLESRISELTSELTDERNTGESAS 1309
Query: 258 ILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEED 317
LL+ + + E EL+ +KK+M + + R + G V D D
Sbjct: 1310 QLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD---D 1366
Query: 318 AGELSRESMWDLSCE-TVRE------QLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFND 370
AG W L E VRE +L + + + + +L+ ++ + +
Sbjct: 1367 AG-----GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
Query: 371 EDVIS-------RQDHEQETEKLELEIQQCKEM-IKTQQQLLQQQLATAYDDDTTSLLRD 422
+ + R E + KL LE QQ + ++ +Q+ +L+ A+++ L+
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
Query: 423 CYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLE 463
L EK+ L E K+Q + + + FT+ + L E
Sbjct: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAE 1522
Score = 37.7 bits (86), Expect = 0.031
Identities = 59/272 (21%), Positives = 117/272 (43%), Gaps = 28/272 (10%)
Query: 120 VETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDE 179
VE ++L L +D + + L+EQL +RE +Q R L+ ++++L+K K
Sbjct: 1711 VEIEDLHL--QIDDIAKAKTALEEQLSRLQREKNEIQNR---LEEDQEDMNELMKKHKAA 1765
Query: 180 VQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKR 239
V + +A + ++ +E +L+E+L L + + +M + V R + K
Sbjct: 1766 VAQASRDLA-QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKI 1824
Query: 240 GSWRT----GKTEARNEDEMYKILLNDY----EYRQKQILMENAE------LKKVLQQMK 285
T +T+ + + + L + E R ++I EN E L++ L+ K
Sbjct: 1825 RELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1884
Query: 286 KEMISLLSPQKKKPRERVD-----DSTGTVISDVEEDAGELSRESMWDLSCETVREQLTN 340
+EM L + + R++ + +S ++ D +L+ + + DL E ++
Sbjct: 1885 EEMGELARKEAEASRKKHELEMDLESLEAANQSLQADL-KLAFKRIGDLQAAIEDEMESD 1943
Query: 341 SIRKQWRILKSHVEKLDNQVSKVHLEGFNDED 372
L+ V K + +K LEG +D D
Sbjct: 1944 ENEDLINSLQDMVTKYQKRKNK--LEGDSDVD 1973
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 56.6 bits (135), Expect = 7e-08
Identities = 79/418 (18%), Positives = 180/418 (43%), Gaps = 38/418 (9%)
Query: 84 ESKGKETKRELNIVAVLNCMNELLVLQRKNL---LAQENVETQNLKLGSDMDHLQSCYSK 140
E++ KETK A+ M + L+R N E++ + +G + L+
Sbjct: 1470 EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRA 1529
Query: 141 LKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKR 200
L++Q+E + + L+E + +LQ +L N + + + + R Q K+
Sbjct: 1530 LEQQVEEMKTQ---LEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQ 1586
Query: 201 KEREYNKLK-----ERLHQLVMNKKDKKIAMDILNYVGRADGKRGSW-----RTGKTEAR 250
R+ +++ ER + + KK+ MD+ + D + + K +A+
Sbjct: 1587 LVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQ 1646
Query: 251 NEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISL------LSPQKKKPRERVD 304
+D M + L+D +++IL + E +K L+ M+ EMI L K++ ++ D
Sbjct: 1647 MKDCMRE--LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 1704
Query: 305 DSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVH 364
+ + + + A L + + + E+L + ++ ++K + Q+ +++
Sbjct: 1705 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE-QGNTELINDRLKKANLQIDQIN 1763
Query: 365 LE-----GFNDEDVISRQDHEQETEKLELEIQQCKEMIK-------TQQQLLQQQLATAY 412
+ ++ +RQ E++ ++L++++Q+ + +K T + QL
Sbjct: 1764 TDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQL 1823
Query: 413 DDDTTSLLRDCYLLEEKE-RLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEE 469
D++T C + E +LK+ ++++N E+ + +A+ RL ++ EE
Sbjct: 1824 DNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEE 1881
Score = 45.4 bits (106), Expect = 2e-04
Identities = 87/429 (20%), Positives = 179/429 (41%), Gaps = 50/429 (11%)
Query: 59 EDNIEQSISYLDQELTT---FGFPSLYEESKGKETKRELNIVAVLNCM--NELLVLQRK- 112
+ NI++ L++E + + E+K K+ + E I+ NC E +L+ +
Sbjct: 942 QQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRI 1001
Query: 113 -----NLLAQENVETQNLKLGS-------DMDHLQSCYSKLKEQLETSRREMIG----LQ 156
NL +E KL + D++ K +++LE +RR++ G L
Sbjct: 1002 AEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLS 1061
Query: 157 ERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKR---KEREYNKLKERL- 212
++ +LQ + L L +++E+Q + A Q N +K+ E + ++L+E L
Sbjct: 1062 DQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE 1121
Query: 213 -HQLVMNKKDKK---IAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQK 268
+ NK +K+ + ++ + S + ++ IL E K
Sbjct: 1122 SERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAK 1181
Query: 269 QILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWD 328
+ E+++ Q +E+ L Q K+ + ++ + T +E + GEL+ E
Sbjct: 1182 THEAQIQEMRQKHSQAVEELAEQLE-QTKRVKANLEKAKQT----LENERGELANEVKVL 1236
Query: 329 LSCETVREQLTNSIRKQWRILKSHVE-------KLDNQVSKVHLEGFNDEDVISRQDHEQ 381
L + E + Q + L+ +L ++V+K+ +E N ++S+ D
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSD--S 1294
Query: 382 ETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLE-EKERLKEEWSLFK 440
++ KL + + ++ Q+LLQ++ + SL +E EK +E+ +
Sbjct: 1295 KSSKLTKDFSALESQLQDTQELLQEE-----NRQKLSLSTKLKQVEDEKNSFREQLEEEE 1349
Query: 441 EQKKNFERE 449
E K N E++
Sbjct: 1350 EAKHNLEKQ 1358
Score = 36.2 bits (82), Expect = 0.091
Identities = 74/379 (19%), Positives = 155/379 (40%), Gaps = 54/379 (14%)
Query: 100 LNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERD 159
+ C+ ++RK E + ++ + + D L+ ++L+++L+ ++ ++
Sbjct: 1377 VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSA 1436
Query: 160 RQLQCKNRNLHQLLKNEKD--------------EVQKLQNIIASRATQYNHDMKRK---E 202
L+ K + QLL EK E ++ + S A M++K E
Sbjct: 1437 CNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELE 1496
Query: 203 REYNKLKERLHQLVMNKKDKKIAMDILNYVGRA-DGKRGSWRTGKTEARN-----EDEMY 256
R + + + L+ +K D ++ L RA + + +T E + ED
Sbjct: 1497 RLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKL 1556
Query: 257 KILLN----------DYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDS 306
++ +N D + R +Q + E KK L + +EM + L ++K+ V
Sbjct: 1557 RLEVNLQAMKAQFERDLQGRDEQ----SEEKKKQLVRQVREMEAELEDERKQRSMAV--- 1609
Query: 307 TGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLE 366
+E D +L E+ D S R++ +RK +K + +LD+
Sbjct: 1610 --AARKKLEMDLKDL--EAHID-SANKNRDEAIKQLRKLQAQMKDCMRELDD------TR 1658
Query: 367 GFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQL---LQQQLATAYDDDTTSLLRDC 423
+E + +++E++ + +E E+ Q +E + ++ QQ+ D+ S +
Sbjct: 1659 ASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGA 1718
Query: 424 YLLEEKERLKEEWSLFKEQ 442
LEEK RL+ + +E+
Sbjct: 1719 LALEEKRRLEARIAQLEEE 1737
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 56.6 bits (135), Expect = 7e-08
Identities = 77/347 (22%), Positives = 147/347 (42%), Gaps = 38/347 (10%)
Query: 121 ETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEV 180
E + +KL D+ L S +E L+ R+ + + + RQL+ + +L L E +
Sbjct: 1300 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1359
Query: 181 QKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRG 240
Q L+ I++ Q + D K+K +++ E L + K+ +I N + + K
Sbjct: 1360 QNLERHISTLNIQLS-DSKKKLQDFASTVEALEE-----GKKRFQKEIENLTQQYEEKAA 1413
Query: 241 SW-RTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKP 299
++ + KT+ R + E+ ++++ RQ L+ N E K +++ LL+ +K
Sbjct: 1414 AYDKLEKTKNRLQQELDDLVVDLDNQRQ---LVSNLEKK------QRKFDQLLAEEKNIS 1464
Query: 300 RERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQ 359
+ D+ E++ LS + + E E + + ++LK+ +E L
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKEE-----LERTNKMLKAEMEDL--- 1516
Query: 360 VSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSL 419
+ +D + + HE E K LE Q E +KTQ + L+ +L D L
Sbjct: 1517 --------VSSKDDVGKNVHELEKSKRALETQM--EEMKTQLEELEDELQATED---AKL 1563
Query: 420 LRDCYLLEEKERLKEEWSLFKEQKKNFERE-RRSFTEAAIRLGLERK 465
+ + K + + + EQ + R+ +R E L ERK
Sbjct: 1564 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610
Score = 38.1 bits (87), Expect = 0.024
Identities = 60/365 (16%), Positives = 157/365 (43%), Gaps = 46/365 (12%)
Query: 118 ENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK 177
EN+ Q + + D L+ ++L+++L+ ++ ++ L+ K R QLL EK
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 178 DEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADG 237
+ + + A + + + KE + L L + + K++ ++ N + +A+
Sbjct: 1462 N----ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE----LERTNKMLKAE- 1512
Query: 238 KRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKK 297
+ ++D++ K +++ E ++ + + E+K L++++ E+
Sbjct: 1513 -------MEDLVSSKDDVGK-NVHELEKSKRALETQMEEMKTQLEELEDEL--------- 1555
Query: 298 KPRERVDDSTGTVISDVEEDAGELSRE-SMWDLSCETVREQLTNSI----------RKQW 346
+ +D+ + +++ G+ R+ D E R QL + RKQ
Sbjct: 1556 ---QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR 1612
Query: 347 RILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQ 406
+ + +KL+ + + L+ D + R++ ++ KL+ +++ + ++ + +
Sbjct: 1613 ALAAAAKKKLEGDLKDLELQA--DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDE 1670
Query: 407 QLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKA 466
ATA +++ + + L++ L+E+ + + +K + E+ E R A
Sbjct: 1671 IFATAKENEKKAKSLEADLMQ----LQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1726
Query: 467 FEEER 471
++E+
Sbjct: 1727 LQDEK 1731
Score = 36.2 bits (82), Expect = 0.091
Identities = 83/400 (20%), Positives = 163/400 (40%), Gaps = 75/400 (18%)
Query: 84 ESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKE 143
E K + K+E + A L +++ +AQ+N + ++ L+ S L+E
Sbjct: 1080 ELKMQLAKKEEELQAALARLDD--------EIAQKNNALKKIR------ELEGHISDLQE 1125
Query: 144 QLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKER 203
L++ R + + + R+L + L+ K E L++ + S ATQ KR E+
Sbjct: 1126 DLDSERAAR-------NKAEKQKRDLGEELEALKTE---LEDTLDSTATQQELRAKR-EQ 1174
Query: 204 EYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDY 263
E LK+ L + + ++ + R E + E +K +
Sbjct: 1175 EVTVLKKALDE------------ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 264 EYRQKQILMENAELK---KVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGE 320
+ ++ + ENA+L +VL Q K+E+ KKK E + V+E +
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEV-----EHKKKKLE----------AQVQELQSK 1267
Query: 321 LSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFN-DEDVISRQDH 379
S E R +L + + K L++ VE + +++ + +DV S
Sbjct: 1268 CS-------DGERARAELNDKVHK----LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1316
Query: 380 EQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLF 439
Q+T++L E + K + T+ + L+++ + D +E K+ L+ S
Sbjct: 1317 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEE-------MEAKQNLERHISTL 1369
Query: 440 KEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQF 479
Q + +++ + F L +K F++E + L QQ+
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN-LTQQY 1408
Score = 35.8 bits (81), Expect = 0.12
Identities = 42/228 (18%), Positives = 99/228 (43%), Gaps = 31/228 (13%)
Query: 84 ESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSK--- 140
+++ K+ +REL +E+ ++N +++E ++L D+ + +
Sbjct: 1651 QAQMKDFQRELEDARASR--DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1708
Query: 141 ----LKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK--------------DEVQK 182
L E+L +S LQ+ R+L+ + L + L+ E+ + ++
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 183 LQNIIAS-RATQYNHDMKRK--EREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKR 239
L N +A+ R+T ++ R+ ER+ +L+ +LH++ K K + + + K
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSK-----FKSTIAALEAKI 1823
Query: 240 GSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKE 287
+ E + L + + K+IL++ + +K+ +Q K++
Sbjct: 1824 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 1871
Score = 31.2 bits (69), Expect = 2.9
Identities = 30/168 (17%), Positives = 71/168 (42%), Gaps = 9/168 (5%)
Query: 117 QENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNE 176
Q N+E + ++ + ++L + T+++ Q+ +RQ + LH++
Sbjct: 1749 QGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1808
Query: 177 KDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRAD 236
K + + + ++ Q ++++ RE + L Q KDKK+ +L + +
Sbjct: 1809 KSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ-----KDKKLKEILL----QVE 1859
Query: 237 GKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQM 284
+R K +A + K L E +++ NA +K+ +++
Sbjct: 1860 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907
Score = 30.4 bits (67), Expect = 5.0
Identities = 36/147 (24%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 345 QWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLEL-EIQQCKEMIKTQQQL 403
QW L + V+ L QV++ E ED + + Q+ + EL E++Q + ++ L
Sbjct: 833 QWWRLFTKVKPL-LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 891
Query: 404 LQQQL---ATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKN----FERERRSFTEA 456
LQ+QL Y + +R +E E + E E++++ + ER+ +
Sbjct: 892 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951
Query: 457 AIRLGLERKAFEEERASWLKQQFLNMT 483
+ L + EEE A+ K Q +T
Sbjct: 952 MLDL---EEQLEEEEAARQKLQLEKVT 975
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 56.6 bits (135), Expect = 7e-08
Identities = 77/347 (22%), Positives = 147/347 (42%), Gaps = 38/347 (10%)
Query: 121 ETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEV 180
E + +KL D+ L S +E L+ R+ + + + RQL+ + +L L E +
Sbjct: 1307 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1366
Query: 181 QKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRG 240
Q L+ I++ Q + D K+K +++ E L + K+ +I N + + K
Sbjct: 1367 QNLERHISTLNIQLS-DSKKKLQDFASTVEALEE-----GKKRFQKEIENLTQQYEEKAA 1420
Query: 241 SW-RTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKP 299
++ + KT+ R + E+ ++++ RQ L+ N E K +++ LL+ +K
Sbjct: 1421 AYDKLEKTKNRLQQELDDLVVDLDNQRQ---LVSNLEKK------QRKFDQLLAEEKNIS 1471
Query: 300 RERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQ 359
+ D+ E++ LS + + E E + + ++LK+ +E L
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKEE-----LERTNKMLKAEMEDL--- 1523
Query: 360 VSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSL 419
+ +D + + HE E K LE Q E +KTQ + L+ +L D L
Sbjct: 1524 --------VSSKDDVGKNVHELEKSKRALETQM--EEMKTQLEELEDELQATED---AKL 1570
Query: 420 LRDCYLLEEKERLKEEWSLFKEQKKNFERE-RRSFTEAAIRLGLERK 465
+ + K + + + EQ + R+ +R E L ERK
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1617
Score = 38.1 bits (87), Expect = 0.024
Identities = 60/365 (16%), Positives = 157/365 (43%), Gaps = 46/365 (12%)
Query: 118 ENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK 177
EN+ Q + + D L+ ++L+++L+ ++ ++ L+ K R QLL EK
Sbjct: 1409 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1468
Query: 178 DEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADG 237
+ + + A + + + KE + L L + + K++ ++ N + +A+
Sbjct: 1469 N----ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE----LERTNKMLKAE- 1519
Query: 238 KRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKK 297
+ ++D++ K +++ E ++ + + E+K L++++ E+
Sbjct: 1520 -------MEDLVSSKDDVGK-NVHELEKSKRALETQMEEMKTQLEELEDEL--------- 1562
Query: 298 KPRERVDDSTGTVISDVEEDAGELSRE-SMWDLSCETVREQLTNSI----------RKQW 346
+ +D+ + +++ G+ R+ D E R QL + RKQ
Sbjct: 1563 ---QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR 1619
Query: 347 RILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQ 406
+ + +KL+ + + L+ D + R++ ++ KL+ +++ + ++ + +
Sbjct: 1620 ALAAAAKKKLEGDLKDLELQA--DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDE 1677
Query: 407 QLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKA 466
ATA +++ + + L++ L+E+ + + +K + E+ E R A
Sbjct: 1678 IFATAKENEKKAKSLEADLMQ----LQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1733
Query: 467 FEEER 471
++E+
Sbjct: 1734 LQDEK 1738
Score = 36.2 bits (82), Expect = 0.091
Identities = 83/400 (20%), Positives = 163/400 (40%), Gaps = 75/400 (18%)
Query: 84 ESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKE 143
E K + K+E + A L +++ +AQ+N + ++ L+ S L+E
Sbjct: 1087 ELKMQLAKKEEELQAALARLDD--------EIAQKNNALKKIR------ELEGHISDLQE 1132
Query: 144 QLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKER 203
L++ R + + + R+L + L+ K E L++ + S ATQ KR E+
Sbjct: 1133 DLDSERAAR-------NKAEKQKRDLGEELEALKTE---LEDTLDSTATQQELRAKR-EQ 1181
Query: 204 EYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDY 263
E LK+ L + + ++ + R E + E +K +
Sbjct: 1182 EVTVLKKALDE------------ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1229
Query: 264 EYRQKQILMENAELK---KVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGE 320
+ ++ + ENA+L +VL Q K+E+ KKK E + V+E +
Sbjct: 1230 DKNKQTLEKENADLAGELRVLGQAKQEV-----EHKKKKLE----------AQVQELQSK 1274
Query: 321 LSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFN-DEDVISRQDH 379
S E R +L + + K L++ VE + +++ + +DV S
Sbjct: 1275 CS-------DGERARAELNDKVHK----LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1323
Query: 380 EQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLF 439
Q+T++L E + K + T+ + L+++ + D +E K+ L+ S
Sbjct: 1324 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEE-------MEAKQNLERHISTL 1376
Query: 440 KEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQF 479
Q + +++ + F L +K F++E + L QQ+
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN-LTQQY 1415
Score = 35.8 bits (81), Expect = 0.12
Identities = 42/228 (18%), Positives = 99/228 (43%), Gaps = 31/228 (13%)
Query: 84 ESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSK--- 140
+++ K+ +REL +E+ ++N +++E ++L D+ + +
Sbjct: 1658 QAQMKDFQRELEDARASR--DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1715
Query: 141 ----LKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK--------------DEVQK 182
L E+L +S LQ+ R+L+ + L + L+ E+ + ++
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 183 LQNIIAS-RATQYNHDMKRK--EREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKR 239
L N +A+ R+T ++ R+ ER+ +L+ +LH++ K K + + + K
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSK-----FKSTIAALEAKI 1830
Query: 240 GSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKE 287
+ E + L + + K+IL++ + +K+ +Q K++
Sbjct: 1831 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 1878
Score = 31.2 bits (69), Expect = 2.9
Identities = 30/168 (17%), Positives = 71/168 (42%), Gaps = 9/168 (5%)
Query: 117 QENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNE 176
Q N+E + ++ + ++L + T+++ Q+ +RQ + LH++
Sbjct: 1756 QGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1815
Query: 177 KDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRAD 236
K + + + ++ Q ++++ RE + L Q KDKK+ +L + +
Sbjct: 1816 KSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ-----KDKKLKEILL----QVE 1866
Query: 237 GKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQM 284
+R K +A + K L E +++ NA +K+ +++
Sbjct: 1867 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1914
Score = 30.4 bits (67), Expect = 5.0
Identities = 36/147 (24%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 345 QWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLEL-EIQQCKEMIKTQQQL 403
QW L + V+ L QV++ E ED + + Q+ + EL E++Q + ++ L
Sbjct: 840 QWWRLFTKVKPL-LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 898
Query: 404 LQQQL---ATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKN----FERERRSFTEA 456
LQ+QL Y + +R +E E + E E++++ + ER+ +
Sbjct: 899 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958
Query: 457 AIRLGLERKAFEEERASWLKQQFLNMT 483
+ L + EEE A+ K Q +T
Sbjct: 959 MLDL---EEQLEEEEAARQKLQLEKVT 982
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 56.6 bits (135), Expect = 7e-08
Identities = 77/347 (22%), Positives = 147/347 (42%), Gaps = 38/347 (10%)
Query: 121 ETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEV 180
E + +KL D+ L S +E L+ R+ + + + RQL+ + +L L E +
Sbjct: 1307 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1366
Query: 181 QKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRG 240
Q L+ I++ Q + D K+K +++ E L + K+ +I N + + K
Sbjct: 1367 QNLERHISTLNIQLS-DSKKKLQDFASTVEALEE-----GKKRFQKEIENLTQQYEEKAA 1420
Query: 241 SW-RTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKP 299
++ + KT+ R + E+ ++++ RQ L+ N E K +++ LL+ +K
Sbjct: 1421 AYDKLEKTKNRLQQELDDLVVDLDNQRQ---LVSNLEKK------QRKFDQLLAEEKNIS 1471
Query: 300 RERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQ 359
+ D+ E++ LS + + E E + + ++LK+ +E L
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKEE-----LERTNKMLKAEMEDL--- 1523
Query: 360 VSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSL 419
+ +D + + HE E K LE Q E +KTQ + L+ +L D L
Sbjct: 1524 --------VSSKDDVGKNVHELEKSKRALETQM--EEMKTQLEELEDELQATED---AKL 1570
Query: 420 LRDCYLLEEKERLKEEWSLFKEQKKNFERE-RRSFTEAAIRLGLERK 465
+ + K + + + EQ + R+ +R E L ERK
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1617
Score = 38.1 bits (87), Expect = 0.024
Identities = 60/365 (16%), Positives = 157/365 (43%), Gaps = 46/365 (12%)
Query: 118 ENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK 177
EN+ Q + + D L+ ++L+++L+ ++ ++ L+ K R QLL EK
Sbjct: 1409 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1468
Query: 178 DEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADG 237
+ + + A + + + KE + L L + + K++ ++ N + +A+
Sbjct: 1469 N----ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE----LERTNKMLKAE- 1519
Query: 238 KRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKK 297
+ ++D++ K +++ E ++ + + E+K L++++ E+
Sbjct: 1520 -------MEDLVSSKDDVGK-NVHELEKSKRALETQMEEMKTQLEELEDEL--------- 1562
Query: 298 KPRERVDDSTGTVISDVEEDAGELSRE-SMWDLSCETVREQLTNSI----------RKQW 346
+ +D+ + +++ G+ R+ D E R QL + RKQ
Sbjct: 1563 ---QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR 1619
Query: 347 RILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQ 406
+ + +KL+ + + L+ D + R++ ++ KL+ +++ + ++ + +
Sbjct: 1620 ALAAAAKKKLEGDLKDLELQA--DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDE 1677
Query: 407 QLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKA 466
ATA +++ + + L++ L+E+ + + +K + E+ E R A
Sbjct: 1678 IFATAKENEKKAKSLEADLMQ----LQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1733
Query: 467 FEEER 471
++E+
Sbjct: 1734 LQDEK 1738
Score = 36.2 bits (82), Expect = 0.091
Identities = 83/400 (20%), Positives = 163/400 (40%), Gaps = 75/400 (18%)
Query: 84 ESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKE 143
E K + K+E + A L +++ +AQ+N + ++ L+ S L+E
Sbjct: 1087 ELKMQLAKKEEELQAALARLDD--------EIAQKNNALKKIR------ELEGHISDLQE 1132
Query: 144 QLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKER 203
L++ R + + + R+L + L+ K E L++ + S ATQ KR E+
Sbjct: 1133 DLDSERAAR-------NKAEKQKRDLGEELEALKTE---LEDTLDSTATQQELRAKR-EQ 1181
Query: 204 EYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDY 263
E LK+ L + + ++ + R E + E +K +
Sbjct: 1182 EVTVLKKALDE------------ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1229
Query: 264 EYRQKQILMENAELK---KVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGE 320
+ ++ + ENA+L +VL Q K+E+ KKK E + V+E +
Sbjct: 1230 DKNKQTLEKENADLAGELRVLGQAKQEV-----EHKKKKLE----------AQVQELQSK 1274
Query: 321 LSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFN-DEDVISRQDH 379
S E R +L + + K L++ VE + +++ + +DV S
Sbjct: 1275 CS-------DGERARAELNDKVHK----LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1323
Query: 380 EQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLF 439
Q+T++L E + K + T+ + L+++ + D +E K+ L+ S
Sbjct: 1324 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEE-------MEAKQNLERHISTL 1376
Query: 440 KEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQF 479
Q + +++ + F L +K F++E + L QQ+
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN-LTQQY 1415
Score = 35.8 bits (81), Expect = 0.12
Identities = 42/228 (18%), Positives = 99/228 (43%), Gaps = 31/228 (13%)
Query: 84 ESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSK--- 140
+++ K+ +REL +E+ ++N +++E ++L D+ + +
Sbjct: 1658 QAQMKDFQRELEDARASR--DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1715
Query: 141 ----LKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK--------------DEVQK 182
L E+L +S LQ+ R+L+ + L + L+ E+ + ++
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 183 LQNIIAS-RATQYNHDMKRK--EREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKR 239
L N +A+ R+T ++ R+ ER+ +L+ +LH++ K K + + + K
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSK-----FKSTIAALEAKI 1830
Query: 240 GSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKE 287
+ E + L + + K+IL++ + +K+ +Q K++
Sbjct: 1831 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 1878
Score = 31.2 bits (69), Expect = 2.9
Identities = 30/168 (17%), Positives = 71/168 (42%), Gaps = 9/168 (5%)
Query: 117 QENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNE 176
Q N+E + ++ + ++L + T+++ Q+ +RQ + LH++
Sbjct: 1756 QGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1815
Query: 177 KDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRAD 236
K + + + ++ Q ++++ RE + L Q KDKK+ +L + +
Sbjct: 1816 KSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ-----KDKKLKEILL----QVE 1866
Query: 237 GKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQM 284
+R K +A + K L E +++ NA +K+ +++
Sbjct: 1867 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1914
Score = 30.4 bits (67), Expect = 5.0
Identities = 36/147 (24%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 345 QWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLEL-EIQQCKEMIKTQQQL 403
QW L + V+ L QV++ E ED + + Q+ + EL E++Q + ++ L
Sbjct: 840 QWWRLFTKVKPL-LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 898
Query: 404 LQQQL---ATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKN----FERERRSFTEA 456
LQ+QL Y + +R +E E + E E++++ + ER+ +
Sbjct: 899 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958
Query: 457 AIRLGLERKAFEEERASWLKQQFLNMT 483
+ L + EEE A+ K Q +T
Sbjct: 959 MLDL---EEQLEEEEAARQKLQLEKVT 982
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 56.6 bits (135), Expect = 7e-08
Identities = 77/347 (22%), Positives = 147/347 (42%), Gaps = 38/347 (10%)
Query: 121 ETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEV 180
E + +KL D+ L S +E L+ R+ + + + RQL+ + +L L E +
Sbjct: 1300 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1359
Query: 181 QKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRG 240
Q L+ I++ Q + D K+K +++ E L + K+ +I N + + K
Sbjct: 1360 QNLERHISTLNIQLS-DSKKKLQDFASTVEALEE-----GKKRFQKEIENLTQQYEEKAA 1413
Query: 241 SW-RTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKP 299
++ + KT+ R + E+ ++++ RQ L+ N E K +++ LL+ +K
Sbjct: 1414 AYDKLEKTKNRLQQELDDLVVDLDNQRQ---LVSNLEKK------QRKFDQLLAEEKNIS 1464
Query: 300 RERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQ 359
+ D+ E++ LS + + E E + + ++LK+ +E L
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKEE-----LERTNKMLKAEMEDL--- 1516
Query: 360 VSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSL 419
+ +D + + HE E K LE Q E +KTQ + L+ +L D L
Sbjct: 1517 --------VSSKDDVGKNVHELEKSKRALETQM--EEMKTQLEELEDELQATED---AKL 1563
Query: 420 LRDCYLLEEKERLKEEWSLFKEQKKNFERE-RRSFTEAAIRLGLERK 465
+ + K + + + EQ + R+ +R E L ERK
Sbjct: 1564 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610
Score = 38.1 bits (87), Expect = 0.024
Identities = 60/365 (16%), Positives = 157/365 (43%), Gaps = 46/365 (12%)
Query: 118 ENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK 177
EN+ Q + + D L+ ++L+++L+ ++ ++ L+ K R QLL EK
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 178 DEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADG 237
+ + + A + + + KE + L L + + K++ ++ N + +A+
Sbjct: 1462 N----ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE----LERTNKMLKAE- 1512
Query: 238 KRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKK 297
+ ++D++ K +++ E ++ + + E+K L++++ E+
Sbjct: 1513 -------MEDLVSSKDDVGK-NVHELEKSKRALETQMEEMKTQLEELEDEL--------- 1555
Query: 298 KPRERVDDSTGTVISDVEEDAGELSRE-SMWDLSCETVREQLTNSI----------RKQW 346
+ +D+ + +++ G+ R+ D E R QL + RKQ
Sbjct: 1556 ---QATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQR 1612
Query: 347 RILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQ 406
+ + +KL+ + + L+ D + R++ ++ KL+ +++ + ++ + +
Sbjct: 1613 ALAAAAKKKLEGDLKDLELQA--DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDE 1670
Query: 407 QLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKA 466
ATA +++ + + L++ L+E+ + + +K + E+ E R A
Sbjct: 1671 IFATAKENEKKAKSLEADLMQ----LQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1726
Query: 467 FEEER 471
++E+
Sbjct: 1727 LQDEK 1731
Score = 36.2 bits (82), Expect = 0.091
Identities = 83/400 (20%), Positives = 163/400 (40%), Gaps = 75/400 (18%)
Query: 84 ESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKE 143
E K + K+E + A L +++ +AQ+N + ++ L+ S L+E
Sbjct: 1080 ELKMQLAKKEEELQAALARLDD--------EIAQKNNALKKIR------ELEGHISDLQE 1125
Query: 144 QLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKER 203
L++ R + + + R+L + L+ K E L++ + S ATQ KR E+
Sbjct: 1126 DLDSERAAR-------NKAEKQKRDLGEELEALKTE---LEDTLDSTATQQELRAKR-EQ 1174
Query: 204 EYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDY 263
E LK+ L + + ++ + R E + E +K +
Sbjct: 1175 EVTVLKKALDE------------ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 264 EYRQKQILMENAELK---KVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGE 320
+ ++ + ENA+L +VL Q K+E+ KKK E + V+E +
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEV-----EHKKKKLE----------AQVQELQSK 1267
Query: 321 LSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFN-DEDVISRQDH 379
S E R +L + + K L++ VE + +++ + +DV S
Sbjct: 1268 CS-------DGERARAELNDKVHK----LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1316
Query: 380 EQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLF 439
Q+T++L E + K + T+ + L+++ + D +E K+ L+ S
Sbjct: 1317 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEE-------MEAKQNLERHISTL 1369
Query: 440 KEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQF 479
Q + +++ + F L +K F++E + L QQ+
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN-LTQQY 1408
Score = 35.8 bits (81), Expect = 0.12
Identities = 42/228 (18%), Positives = 99/228 (43%), Gaps = 31/228 (13%)
Query: 84 ESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSK--- 140
+++ K+ +REL +E+ ++N +++E ++L D+ + +
Sbjct: 1651 QAQMKDFQRELEDARASR--DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1708
Query: 141 ----LKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEK--------------DEVQK 182
L E+L +S LQ+ R+L+ + L + L+ E+ + ++
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 183 LQNIIAS-RATQYNHDMKRK--EREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKR 239
L N +A+ R+T ++ R+ ER+ +L+ +LH++ K K + + + K
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSK-----FKSTIAALEAKI 1823
Query: 240 GSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKE 287
+ E + L + + K+IL++ + +K+ +Q K++
Sbjct: 1824 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 1871
Score = 31.2 bits (69), Expect = 2.9
Identities = 30/168 (17%), Positives = 71/168 (42%), Gaps = 9/168 (5%)
Query: 117 QENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNE 176
Q N+E + ++ + ++L + T+++ Q+ +RQ + LH++
Sbjct: 1749 QGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1808
Query: 177 KDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRAD 236
K + + + ++ Q ++++ RE + L Q KDKK+ +L + +
Sbjct: 1809 KSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ-----KDKKLKEILL----QVE 1859
Query: 237 GKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQM 284
+R K +A + K L E +++ NA +K+ +++
Sbjct: 1860 DERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907
Score = 30.4 bits (67), Expect = 5.0
Identities = 36/147 (24%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 345 QWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLEL-EIQQCKEMIKTQQQL 403
QW L + V+ L QV++ E ED + + Q+ + EL E++Q + ++ L
Sbjct: 833 QWWRLFTKVKPL-LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 891
Query: 404 LQQQL---ATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKN----FERERRSFTEA 456
LQ+QL Y + +R +E E + E E++++ + ER+ +
Sbjct: 892 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951
Query: 457 AIRLGLERKAFEEERASWLKQQFLNMT 483
+ L + EEE A+ K Q +T
Sbjct: 952 MLDL---EEQLEEEEAARQKLQLEKVT 975
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 56.2 bits (134), Expect = 9e-08
Identities = 62/339 (18%), Positives = 155/339 (45%), Gaps = 26/339 (7%)
Query: 140 KLKEQLETSRRE--MIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHD 197
K++EQ + +E M +E+ R+ + K R + + +++++ + + I Q +
Sbjct: 418 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE 477
Query: 198 MKRKEREYNKLKERLHQLV-MNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMY 256
M R+E + ++ +E Q M+++++KI + WR + E+++
Sbjct: 478 MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ----------EEKVWRQEEKIREQEEKIR 527
Query: 257 KILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEE 316
+ + +RQ++ + E E+ + ++M ++ +++ R+ +D + E
Sbjct: 528 E--QEEKMWRQEEKIREQEEMWREEEKMHEQE----KIWEEEKRQEQEDKMWRQEEKIRE 581
Query: 317 DAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISR 376
++ R+ E R++ + KQ ++ EK+ Q K+ E+ I
Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR----EQEEKIRE 637
Query: 377 QDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEW 436
Q E+ T++ E ++ + +E + Q++ +Q+Q T + + ++ + E++E+++E+
Sbjct: 638 Q--EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE 695
Query: 437 SLFKEQ-KKNFERERRSFTEAAIRLGLERKAFEEERASW 474
+ +EQ +K +E+E + + E K +E W
Sbjct: 696 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
Score = 53.9 bits (128), Expect = 4e-07
Identities = 65/381 (17%), Positives = 173/381 (45%), Gaps = 30/381 (7%)
Query: 117 QENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNE 176
+E ++ K+ + ++ K++EQ E RR+ + E++ ++ R +++ +
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM----RRQEEMMWEK 361
Query: 177 KDEVQKLQNIIASRATQYNHD---MKRKEREYNKLKERLHQL--VMNKKDKKIAMD-ILN 230
++++++ + ++ + + M KE + +L+E++H+ + +++K+ + I
Sbjct: 362 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 421
Query: 231 YVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMIS 290
R + + WR + E+++ + +RQ++ + E +K+ ++ K++
Sbjct: 422 QEKRQEQEAKMWRQEEKIREQEEKIRE--QEKKMWRQEEKIHEQ---EKIREEEKRQEQE 476
Query: 291 LLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILK 350
+ Q++K E+ + +E+ E +W E +REQ IR+Q +
Sbjct: 477 EMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE-EKIREQ-EEKIREQEEKMW 534
Query: 351 SHVEKLDNQVSKVHLEG-FNDEDVISRQDHEQETE-----------KLELEIQQCKEMIK 398
EK+ Q E ++++ I ++ QE E + E ++ + +E I+
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
Query: 399 TQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAI 458
Q++ Q+Q + + ++ + E++E+++E+ +EQ++ + + E
Sbjct: 595 EQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 654
Query: 459 RL-GLERKAFEEERASWLKQQ 478
++ E K E+E W +++
Sbjct: 655 KMCEQEEKMQEQEETMWRQEE 675
Score = 53.9 bits (128), Expect = 4e-07
Identities = 61/364 (16%), Positives = 163/364 (44%), Gaps = 33/364 (9%)
Query: 110 QRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNL 169
+ + + QE + Q K+ + ++ K++EQ + R+ + E+++ + + R
Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Query: 170 HQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDIL 229
+ + +++++ + + I R + H+ + K R+ + R + + +++K
Sbjct: 475 QEEMWRQEEKIHEQEEIW--RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI------ 526
Query: 230 NYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMI 289
+ + WR + + R ++EM++ + + +++ + E + ++ +M ++
Sbjct: 527 -----REQEEKMWRQ-EEKIREQEEMWR---EEEKMHEQEKIWEEEKRQEQEDKMWRQEE 577
Query: 290 SLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRIL 349
+ ++K R+ I + EE E E MW E +REQ I++Q +
Sbjct: 578 KIREQEEKVWRQEEK------IREQEEKRQE-QEEKMWKQE-EKIREQ-EEKIQEQEEKI 628
Query: 350 KSHVEKLDNQVSKVHLE----GFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQ 405
+ EK+ Q + G +E + +++ QE E+ + + +E I+ Q++ ++
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET---MWRQEEKIREQEKKIR 685
Query: 406 QQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERK 465
+Q + + ++ + E++E++ E+ +EQ++ R+ E +RL + +
Sbjct: 686 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Query: 466 AFEE 469
+E
Sbjct: 746 KMQE 749
Score = 52.0 bits (123), Expect = 2e-06
Identities = 68/368 (18%), Positives = 170/368 (46%), Gaps = 30/368 (8%)
Query: 105 ELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRRE-MIGLQERDRQLQ 163
E++ + + + QE + + + +++ K++EQ E + E I QE+ ++ +
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 164 CKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKK 223
K + ++ +++++++ + + + + + K +E E +R Q M ++++K
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE-----KRQEQEEMWRQEEK 484
Query: 224 IAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQ 283
I + WR + E+++ K + +RQ++ + E E K+ +Q
Sbjct: 485 I-----------HEQEEIWRQKEKMHEQEEKIRK--QEEKVWRQEEKIREQEE--KIREQ 529
Query: 284 MKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIR 343
+K ++++ R ++ EE+ + + MW E +REQ R
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE-EKIREQEEKVWR 588
Query: 344 KQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQL 403
++ +I + EK Q K+ + E+ I Q E++ ++ E +I++ +E I+ Q+++
Sbjct: 589 QEEKI-REQEEKRQEQEEKM----WKQEEKIREQ--EEKIQEQEEKIREQEEKIREQEEM 641
Query: 404 LQQQLATAYDDDTTSLLRDCYLLEEKERL-KEEWSLFKEQKKNFERERRSFTEAAIRLGL 462
Q+Q + + ++ + E++E + ++E + +++KK E+E + + +
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701
Query: 463 ERKAFEEE 470
E K +E+E
Sbjct: 702 EEKMWEQE 709
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.127 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,877,725
Number of Sequences: 37866
Number of extensions: 1042382
Number of successful extensions: 7199
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 653
Number of HSP's that attempted gapping in prelim test: 4769
Number of HSP's gapped (non-prelim): 2206
length of query: 614
length of database: 18,247,518
effective HSP length: 108
effective length of query: 506
effective length of database: 14,157,990
effective search space: 7163942940
effective search space used: 7163942940
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.