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Search of human proteins with 40807469
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40807469 TRAF interacting protein [Homo sapiens]
(469 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40807469 TRAF interacting protein [Homo sapiens] 925 0.0
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 61 2e-09
gi|71061468 centromere protein E [Homo sapiens] 58 2e-08
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 58 2e-08
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 58 2e-08
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 57 4e-08
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 57 4e-08
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 57 4e-08
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 57 5e-08
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 55 1e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 55 1e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 55 1e-07
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 55 1e-07
gi|33946313 ninein isoform 4 [Homo sapiens] 55 1e-07
gi|33946321 ninein isoform 5 [Homo sapiens] 55 1e-07
gi|148536871 ninein isoform 1 [Homo sapiens] 55 1e-07
gi|148536869 ninein isoform 2 [Homo sapiens] 55 1e-07
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 55 2e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 55 2e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 55 2e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 55 2e-07
gi|143770880 laminin, beta 4 [Homo sapiens] 54 2e-07
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 54 2e-07
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 54 2e-07
gi|31542661 transmembrane protein 57 [Homo sapiens] 54 3e-07
gi|58530840 desmoplakin isoform I [Homo sapiens] 54 4e-07
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 54 4e-07
gi|51317366 myosin XVIIIB [Homo sapiens] 54 4e-07
gi|150170725 zinc and ring finger 4 [Homo sapiens] 54 4e-07
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 54 4e-07
>gi|40807469 TRAF interacting protein [Homo sapiens]
Length = 469
Score = 925 bits (2390), Expect = 0.0
Identities = 469/469 (100%), Positives = 469/469 (100%)
Query: 1 MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKRTIIN 60
MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKRTIIN
Sbjct: 1 MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKRTIIN 60
Query: 61 KLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVS 120
KLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVS
Sbjct: 61 KLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVS 120
Query: 121 LQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEV 180
LQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEV
Sbjct: 121 LQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEV 180
Query: 181 EEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVY 240
EEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVY
Sbjct: 181 EEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVY 240
Query: 241 SELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVE 300
SELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVE
Sbjct: 241 SELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVE 300
Query: 301 VNLKLRRPSFRDDIDLNATFDVDTPPARPSSSQHGYYEKLCLEKSHSPIQDVPKKICKGP 360
VNLKLRRPSFRDDIDLNATFDVDTPPARPSSSQHGYYEKLCLEKSHSPIQDVPKKICKGP
Sbjct: 301 VNLKLRRPSFRDDIDLNATFDVDTPPARPSSSQHGYYEKLCLEKSHSPIQDVPKKICKGP 360
Query: 361 RKESQLSLGGQSCAGEPDEELVGAFPIFVRNAILGQKQPKRPRSESSCSKDVVRTGFDGL 420
RKESQLSLGGQSCAGEPDEELVGAFPIFVRNAILGQKQPKRPRSESSCSKDVVRTGFDGL
Sbjct: 361 RKESQLSLGGQSCAGEPDEELVGAFPIFVRNAILGQKQPKRPRSESSCSKDVVRTGFDGL 420
Query: 421 GGRTKFIQPTDTVMIRPLPVKPKTKVKQRVRVKTVPSLFQAKLDTFLWS 469
GGRTKFIQPTDTVMIRPLPVKPKTKVKQRVRVKTVPSLFQAKLDTFLWS
Sbjct: 421 GGRTKFIQPTDTVMIRPLPVKPKTKVKQRVRVKTVPSLFQAKLDTFLWS 469
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 61.2 bits (147), Expect = 2e-09
Identities = 58/242 (23%), Positives = 108/242 (44%), Gaps = 32/242 (13%)
Query: 68 QEEENVLDAEFLKNELD------NVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSL 121
+E ++L+ K E D V+A L +K++E R + ++ L+ +LE+ V SL
Sbjct: 1132 REHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSL 1191
Query: 122 QQALGKAEMLCSTLKKQMKYLEQQQDETK-------------QAQEEARRLRSKMKTME- 167
++ + A++ ++ K + E K QA+ + ++R + E
Sbjct: 1192 KEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEI 1251
Query: 168 ---QIELL-----LQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASG 219
Q EL LQ + +++E + VG +E L ++E ++LK+ +
Sbjct: 1252 AQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTE 1311
Query: 220 EVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL-TMLQETL 278
+ RK+L + LQ V SEL+ A+ +L QKD ++ LK + T+LQ+
Sbjct: 1312 QQG---RKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQ 1368
Query: 279 NL 280
L
Sbjct: 1369 QL 1370
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/212 (21%), Positives = 91/212 (42%), Gaps = 23/212 (10%)
Query: 77 EFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLK 136
E L+ E ++ QL+ + + + +D L+ +E A + LQ E L+
Sbjct: 713 EALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQ 772
Query: 137 KQMKYLEQQQDETKQAQEEARRLRSKMK--TMEQIELLLQSQRPEVEEMIRDMGVGQSAV 194
+ LE K +EE R +++ T E E L E++ ++ + V
Sbjct: 773 NEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETL--------EKLREELAIKSGQV 824
Query: 195 EQLAVYCVSLKKEYENLK----------EARKASGEVADKLRKDLFSSRSKLQTVYSELD 244
E L +LKK+ + +K EA + D+L +L ++R +L SEL
Sbjct: 825 EHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLD---SELK 881
Query: 245 QAKLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
+ + EL + ++A+ E+ L +++ +++
Sbjct: 882 ELRQELMQVHGEKRTAEAELSRLHREVAQVRQ 913
Score = 45.4 bits (106), Expect = 1e-04
Identities = 48/206 (23%), Positives = 98/206 (47%), Gaps = 27/206 (13%)
Query: 79 LKNELDNVRAQLSQK----DKEKRDS---QVIIDTLRDTLEERNATVVSLQQALGKAEML 131
LK ++ ++ Q Q+ + +RD+ +I L+ T + ++ + L+Q L +
Sbjct: 834 LKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGE 893
Query: 132 CSTLKKQMKYLEQQQDETKQAQEEAR-RLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVG 190
T + ++ L ++ + +Q + L+S K +++E LQS + + E+M+
Sbjct: 894 KRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEAN 953
Query: 191 QSAVEQLAVYCVSLKKEYENL-KEARKASGEVADKLRK---DLFSSRSKLQTVYSELDQA 246
+ +LKK+ E L +EARKA E K+R+ DL S++ +++T + + A
Sbjct: 954 E-----------ALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENA 1002
Query: 247 ----KLELKSAQKDLQSADKEIMSLK 268
L+ A ++AD E+ L+
Sbjct: 1003 VGILSRRLQEALAAKEAADAELGQLR 1028
Score = 41.6 bits (96), Expect = 0.002
Identities = 46/222 (20%), Positives = 97/222 (43%), Gaps = 25/222 (11%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L ++++++ + KD D + + L+ L++ +L L ++ S+L+
Sbjct: 515 LMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSV 574
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMK-----TMEQIELL---------LQSQRPEVEEM- 183
++ +QQ AQE RL+ +M M Q LL L Q E +
Sbjct: 575 RQWYQQQ---LALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLTETQHRS 631
Query: 184 IRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQ------ 237
+++ G + ++ + + + + ++EA+ E + ++ R +LQ
Sbjct: 632 MKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSA 691
Query: 238 -TVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
++ +L+Q KL L + L++ +E + L K+LT+ QE L
Sbjct: 692 ASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEAL 733
Score = 37.4 bits (85), Expect = 0.029
Identities = 39/199 (19%), Positives = 85/199 (42%), Gaps = 29/199 (14%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L+ +L+ + + SQ KEK + Q + L L+ A++ CS +Q
Sbjct: 417 LEGQLEALSLEASQALKEKAELQAQLAALSTKLQ---------------AQVECSHSSQQ 461
Query: 139 MK-YLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQL 197
+ L + D KQ+ + R M ++ +L+++ + D+ V + ++L
Sbjct: 462 RQDSLSSEVDTLKQSCWDLER------AMTDLQNMLEAKNASLASSNNDLQVAEEQYQRL 515
Query: 198 AVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDL 257
+ E+++ + + LR+ + + +S+LQ V E +LK++Q ++
Sbjct: 516 MA-------KVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEI 568
Query: 258 QSADKEIMSLKKKLTMLQE 276
S +++L + QE
Sbjct: 569 SSLQSVRQWYQQQLALAQE 587
Score = 31.6 bits (70), Expect = 1.6
Identities = 41/217 (18%), Positives = 91/217 (41%), Gaps = 19/217 (8%)
Query: 70 EENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAE 129
+E + E EL +RAQ D + I L L+ + + L++ L +
Sbjct: 1011 QEALAAKEAADAELGQLRAQGGSSDSSLALHERI-QALEAELQAVSHSKTLLEKELQEVI 1069
Query: 130 MLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGV 189
L S ++++ ++ E + +E+R R K+K +E+ L + + + +G
Sbjct: 1070 ALTS---QELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQ 1126
Query: 190 GQSAV-EQLAVYCVSLKKEYENL--------------KEARKASGEVADKLRKDLFSSRS 234
+A+ E ++ +L K +L +E + + L+ L +
Sbjct: 1127 SNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKE 1186
Query: 235 KLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL 271
K+ ++ ++ AK+E ++ ++A E+ +KK+L
Sbjct: 1187 KVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKEL 1223
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 58.2 bits (139), Expect = 2e-08
Identities = 41/202 (20%), Positives = 101/202 (50%), Gaps = 12/202 (5%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKK- 137
++ +L+N A+L +K +E + ++ + TL+ + E V ++Q + + TL K
Sbjct: 1807 MQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL 1866
Query: 138 QMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQL 197
+++ L Q + + EE + + + + ++E L+ +R +++E +++ ++Q
Sbjct: 1867 EIENLNLAQ-KLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQE 1925
Query: 198 AVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDL 257
L KE++ E DKLR+ + ++ + +LD++K EL+ ++L
Sbjct: 1926 LKTARMLSKEHK----------ETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQEL 1975
Query: 258 QSADKEIMSLKKKLTMLQETLN 279
Q + +++ +K+ + M + +N
Sbjct: 1976 QKKELQLLRVKEDVNMSHKKIN 1997
Score = 52.4 bits (124), Expect = 9e-07
Identities = 58/248 (23%), Positives = 114/248 (45%), Gaps = 35/248 (14%)
Query: 68 QEEENVLDAEFLKNELDNVRAQLSQKDKEK-RDSQVIIDTLRDTLEERNATVVSLQQALG 126
+ +E + + E LK + + + L + E R +Q+ L + LEE + V + L
Sbjct: 1638 ETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQI----LHENLEEMRS-VTKERDDLR 1692
Query: 127 KAEMLCSTLKKQMKYLEQQQDET----KQAQEEAR----RLRSKMKTMEQIELLLQSQRP 178
E TLK + L++ ET + QEE + L+ +T++++ ++ +
Sbjct: 1693 SVE---ETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTN 1749
Query: 179 EVEEMIRDMGVGQSAV--------EQLAVYCVSLKKEYENLKEARKASGEVADKL---RK 227
E+ M +D+ A+ E+L + + LK++ E + + R E DKL +K
Sbjct: 1750 EISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQK 1809
Query: 228 DLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASET 287
DL +S +KLQ EL K+ + L + K++ +KK++ +++ S T
Sbjct: 1810 DLENSNAKLQEKIQEL-------KANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT 1862
Query: 288 VDRLVLES 295
+ +L +E+
Sbjct: 1863 LSKLEIEN 1870
Score = 52.0 bits (123), Expect = 1e-06
Identities = 48/242 (19%), Positives = 115/242 (47%), Gaps = 25/242 (10%)
Query: 60 NKLFFDLAQEEENVL----DAEFLKNELDNVRAQLSQKDKEKRDSQVI-------IDTLR 108
+KLF ++ +E V + K++L ++ D+E ++ + + +
Sbjct: 778 DKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVL 837
Query: 109 DTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQ 168
+ E N +V+L + K + LK ++ Y +T++ QE+ R ++ ++ MEQ
Sbjct: 838 EENERMNQEIVNLSKEAQKFDSSLGALKTELSY------KTQELQEKTREVQERLNEMEQ 891
Query: 169 IELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD 228
++ L+++ ++ + R+ + ++Q +L +E ++LK+ +++ D+L+ D
Sbjct: 892 LKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSD 951
Query: 229 LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLT-MLQETLNLPPVASET 287
+ TV +D + +L++A + L+ + I +LK K++ + L++ ET
Sbjct: 952 IH------DTVNMNIDTQE-QLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGET 1004
Query: 288 VD 289
D
Sbjct: 1005 KD 1006
Score = 45.8 bits (107), Expect = 8e-05
Identities = 57/277 (20%), Positives = 126/277 (45%), Gaps = 40/277 (14%)
Query: 77 EFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLK 136
E L++E D ++ + + + +++ + L+E+ T+ L+ L + E ST++
Sbjct: 1452 EVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQ 1511
Query: 137 KQMKYL--------------------------EQQQDETKQAQEEARRLRSKMKTME--Q 168
KQ++ + +++ +E KQ +E + S ++++E
Sbjct: 1512 KQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKM 1571
Query: 169 IELL--LQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLR 226
+EL LQ + E++ MI++ + E L + LK+ + + K S E +
Sbjct: 1572 LELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFL 1631
Query: 227 KDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASE 286
K ++ ++ Q E++ K + ++ + +L++ + E + L + +L E NL + S
Sbjct: 1632 K--MTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQ---ILHE--NLEEMRSV 1684
Query: 287 TVDRLVLESPAPVEVNLKLRRPSFRDDIDLNATFDVD 323
T +R L S VE LK+ R ++++ T D++
Sbjct: 1685 TKERDDLRS---VEETLKVERDQLKENLRETITRDLE 1718
Score = 45.1 bits (105), Expect = 1e-04
Identities = 52/202 (25%), Positives = 95/202 (47%), Gaps = 29/202 (14%)
Query: 93 KDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQA 152
KD E + Q I +L ++E+N L+ + + E L + LK+ + + T +
Sbjct: 1034 KDNEIIEQQRKIFSL---IQEKNELQQMLESVIAEKEQLKTDLKENI-------EMTIEN 1083
Query: 153 QEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLK 212
QEE R L ++K +Q E++ Q E I+ G ++LA LK++ + L+
Sbjct: 1084 QEELRLLGDELK--KQQEIVAQ----EKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQ 1137
Query: 213 EARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLT 272
E ++ V +++ S++Q +E++ K ELK+ + L+ + E + L +KL
Sbjct: 1138 EKQQQLLNVQEEM--------SEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLN 1189
Query: 273 MLQETLNLPPVASETVDRLVLE 294
N V S T +R VL+
Sbjct: 1190 E-----NYEEVKSITKERKVLK 1206
Score = 43.5 bits (101), Expect = 4e-04
Identities = 42/182 (23%), Positives = 84/182 (46%), Gaps = 23/182 (12%)
Query: 98 RDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEAR 157
++ Q ID LR ++ E+ A +++ Q E + L++++ L ++Q+ +E
Sbjct: 1245 KEHQETIDELRRSVSEKTAQIINTQDL----EKSHTKLQEEIPVLHEEQELLPNVKE--- 1297
Query: 158 RLRSKMKTMEQIELLLQSQ---------RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEY 208
+ +TM ++ELL + R E+E + + +S E SL KE
Sbjct: 1298 -VSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEE-----IKSLTKER 1351
Query: 209 ENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLK 268
+NLK ++A D+L++ + + +K+Q S+ +Q+ L +K + E+ K
Sbjct: 1352 DNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQS-LNMKEKDNETTKIVSEMEQFK 1410
Query: 269 KK 270
K
Sbjct: 1411 PK 1412
Score = 40.8 bits (94), Expect = 0.003
Identities = 44/235 (18%), Positives = 94/235 (40%), Gaps = 31/235 (13%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQA 124
D ++ + +D++ L+N ++ L + K+ Q + D L+ + + +
Sbjct: 589 DQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSEN 648
Query: 125 LGKAEML--CSTLKKQMK-----YLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQR 177
L E + +T KQM+ Y Q + + K + + L+S + ++ L+ +
Sbjct: 649 LELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKV 708
Query: 178 P------------------------EVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKE 213
P E E +R+ + S ++ L L+KE ++ E
Sbjct: 709 PKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSE 768
Query: 214 ARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLK 268
DKL ++ S++Q + E+ + K +L + Q + +S D+E + K
Sbjct: 769 ELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFK 823
Score = 40.4 bits (93), Expect = 0.003
Identities = 52/235 (22%), Positives = 108/235 (45%), Gaps = 45/235 (19%)
Query: 80 KNELDNVRAQLSQKDKEKRDSQVI--IDTLRDTLEERNATVVSLQQALG-KAEMLCST-- 134
KN+LD A L +K K+ ++ Q+I I L++ ++ L+ L K E+L
Sbjct: 531 KNDLDEFEA-LERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKED 589
Query: 135 -LKKQMKYLEQQQDE--------TKQAQEEARRLRSKMKTMEQIEL-------LLQSQRP 178
+KK +Y++ Q+ E + ++ E+ ++++ + E + L L+S+
Sbjct: 590 QIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENL 649
Query: 179 EVEEMIR-----------DMGVGQSAVEQLAVYCVSLKKEYEN-LKEARKASGEVADKLR 226
E++E ++ D+ + QS +E V L+KE ++ E K + + K+
Sbjct: 650 ELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVP 709
Query: 227 KDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLP 281
KDL + + + ++ QK+L +E +L++++ +L E +LP
Sbjct: 710 KDLLCNL-----------ELEGKITDLQKELNKEVEENEALREEVILLSELKSLP 753
Score = 39.7 bits (91), Expect = 0.006
Identities = 41/188 (21%), Positives = 80/188 (42%), Gaps = 5/188 (2%)
Query: 107 LRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRS-KMKT 165
+ D +E N V +AL + +L S LK +E+ + E + EE + S K K
Sbjct: 722 ITDLQKELNKEVEE-NEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKL 780
Query: 166 MEQI---ELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVA 222
++ E +Q E+ + D+ QS + + K + + ++ K E
Sbjct: 781 FSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEEN 840
Query: 223 DKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPP 282
+++ +++ + + Q S L K EL ++LQ +E+ ++ L+E L
Sbjct: 841 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD 900
Query: 283 VASETVDR 290
+TV+R
Sbjct: 901 STLQTVER 908
Score = 37.4 bits (85), Expect = 0.029
Identities = 41/205 (20%), Positives = 83/205 (40%), Gaps = 20/205 (9%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDT-------LRDTLEERNAT 117
DL + L A+ NE+ + ++ +EK + Q ++++ L+ L+E
Sbjct: 1020 DLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEM 1079
Query: 118 VVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQR 177
+ Q+ L +L LKKQ + + Q+++ + + E R ++ +E+ Q
Sbjct: 1080 TIENQEEL---RLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQL 1136
Query: 178 PEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQ 237
E ++ + ++ S +++ E ENLK K + + + KL
Sbjct: 1137 QEKQQQLLNVQEEMSEMQKKI-------NEIENLKNELKNKELTLEHMETERLELAQKLN 1189
Query: 238 TVYSELDQAKLE---LKSAQKDLQS 259
Y E+ E LK QK ++
Sbjct: 1190 ENYEEVKSITKERKVLKELQKSFET 1214
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 57.8 bits (138), Expect = 2e-08
Identities = 54/236 (22%), Positives = 107/236 (45%), Gaps = 37/236 (15%)
Query: 61 KLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVS 120
K D+ + + NVL + +++N++ QL K+K+ + + +L+ + + +
Sbjct: 563 KDMLDVKERKVNVL-----QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTT 617
Query: 121 LQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEV 180
L++AL + E LK EQ+ + ++ QEE + +K +++ LLQ E
Sbjct: 618 LEEALAEKERTIERLK------EQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEK 671
Query: 181 EEMIRDMGVGQS------------------AVEQLAVYCV----SLKKEYENLKEARKAS 218
E + D+ S A+EQ C+ LKK +E EAR AS
Sbjct: 672 EASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEAR-AS 730
Query: 219 GEVADK---LRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL 271
E++D+ L +++ + + +E+D+ LK + + DK+I L++++
Sbjct: 731 PEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQV 786
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/227 (23%), Positives = 105/227 (46%), Gaps = 23/227 (10%)
Query: 67 AQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALG 126
AQ EE A L+ E+ V+ +LS+KD E Q ++TL + + + L+++L
Sbjct: 452 AQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 511
Query: 127 KAEMLCSTLKKQMKYLEQQQDE--------TKQAQEEARRLRSKMKTMEQIELLLQSQRP 178
E + L+ ++ L + +E TKQ Q+ A ++ + ++ +L
Sbjct: 512 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML----- 566
Query: 179 EVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLF------SS 232
+V+E R + V Q +E L +K+ +LKE K+ AD D +
Sbjct: 567 DVKE--RKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSL--QADTTNTDTALTTLEEAL 622
Query: 233 RSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLN 279
K +T+ +Q + + Q+++ + K++ LK+K+++LQ L+
Sbjct: 623 AEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLS 669
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/242 (22%), Positives = 104/242 (42%), Gaps = 18/242 (7%)
Query: 82 ELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKY 141
E+D + L + + EK D I L ++++N V +L+ + + + ++ +
Sbjct: 757 EVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARR 816
Query: 142 LEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSA-------V 194
E +++ Q +++ LR K +E++E L+ E + +SA V
Sbjct: 817 REDNLNDSSQQLQDS--LRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQV 874
Query: 195 EQLAVYCVSLKKEYENLKEARKASGE-VADKLR--KDLFSSRSKLQTVYSELDQAKLELK 251
E+L + +K+E E++K ++ + +A+K +L + R K E+ Q L
Sbjct: 875 EELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAA 934
Query: 252 SAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRRPSFR 311
++KD A E+ S KKK T DRLV + + +KL ++
Sbjct: 935 ISEKDANIALLELSSSKKK------TQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYE 988
Query: 312 DD 313
DD
Sbjct: 989 DD 990
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/248 (21%), Positives = 112/248 (45%), Gaps = 46/248 (18%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQA 124
DL+++E ++LD LK ++ + +KD + TL LE++ + ++
Sbjct: 667 DLSEKEASLLD---LKEHASSLASSGLKKDSR-------LKTLEIALEQKKEECLKMESQ 716
Query: 125 LGKAEMLC------STLKKQMKYLEQQ----QDETKQAQEEARRLRSKMKTMEQIELLLQ 174
L KA + ++++LE++ +DE+ +AQ E RL +K +E +
Sbjct: 717 LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKD 776
Query: 175 SQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARK-------ASGEVADKLRK 227
+ E+E ++D + ++ V KK + L+EAR+ +S ++ D LRK
Sbjct: 777 KKIAELERQVKDQNKKVANLKHKEQ--VEKKKSAQMLEEARRREDNLNDSSQQLQDSLRK 834
Query: 228 ------DLFSSRSKLQTVYSELDQAKLELKSAQKD-----------LQSADKEIMSLKKK 270
+L + + + +E + + +SA+ + ++ +E+ S+K K
Sbjct: 835 KDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAK 894
Query: 271 LTMLQETL 278
L+ Q++L
Sbjct: 895 LSSTQQSL 902
Score = 40.8 bits (94), Expect = 0.003
Identities = 46/242 (19%), Positives = 100/242 (41%), Gaps = 33/242 (13%)
Query: 67 AQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQ--- 123
A+ E + L+ L+ + ++ + + I L + L+ + + + ++
Sbjct: 272 AEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHE 331
Query: 124 ---ALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRL------RSKMKTMEQIELLLQ 174
L +AEM L+ LEQ++ E +EE R +K K ++ + +
Sbjct: 332 RTRRLAEAEMHVHHLES---LLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKD 388
Query: 175 SQRPEVEEMIRDMGVG---------------QSAVEQLAVY---CVSLKKEYENLKEARK 216
S+ +E +RD+ + ++Q+ VY +K + E LKE
Sbjct: 389 SKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELS 448
Query: 217 ASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
+ ++L+K ++++ V EL + EL + Q L++ + K+ + +L+E
Sbjct: 449 SKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE 508
Query: 277 TL 278
+L
Sbjct: 509 SL 510
Score = 38.5 bits (88), Expect = 0.013
Identities = 56/270 (20%), Positives = 103/270 (38%), Gaps = 33/270 (12%)
Query: 59 INKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATV 118
+N+LF Q++ + E EL Q + E++ ++ + LR TLEE +
Sbjct: 242 LNQLF----QQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFL--LRKTLEEMELRI 295
Query: 119 VSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRP 178
+ +Q L + L + ++ T++ E RRL + +E LL+ +
Sbjct: 296 ETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEK 355
Query: 179 EV----EEMIRDMGVGQSAVEQLAVYCV----------------SLKKEYENLKEARKAS 218
E EEM R + + A+ V L++E + LK S
Sbjct: 356 ENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALS 415
Query: 219 GEVADKLRKDLFSSRS-------KLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL 271
E ++ K + RS K++ + EL + + + +K EI +K++L
Sbjct: 416 TEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQEL 475
Query: 272 TMLQETLNLPPVASETVDRLVLESPAPVEV 301
+ L ET+ +S +EV
Sbjct: 476 SRKDTELLALQTKLETLTNQFSDSKQHIEV 505
Score = 35.0 bits (79), Expect = 0.15
Identities = 41/217 (18%), Positives = 98/217 (45%), Gaps = 28/217 (12%)
Query: 68 QEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEER------NATVVSL 121
+ + +AE + L+++ L QK+KE LR+ + R +A +L
Sbjct: 331 ERTRRLAEAEMHVHHLESL---LEQKEKEN-------SMLREEMHRRFENAPDSAKTKAL 380
Query: 122 QQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSK-MKTMEQIELLLQSQRPEV 180
Q + + S++++ ++ LE++ K + R + MK ME + + +V
Sbjct: 381 QTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKV 440
Query: 181 EEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD--LFSSRSKLQT 238
E++ ++ ++ E+L L+ E +K+ + RKD L + ++KL+T
Sbjct: 441 EQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQ---------ELSRKDTELLALQTKLET 491
Query: 239 VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQ 275
+ ++ +K ++ ++ L + ++ L+ ++ L+
Sbjct: 492 LTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALR 528
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 57.8 bits (138), Expect = 2e-08
Identities = 54/236 (22%), Positives = 107/236 (45%), Gaps = 37/236 (15%)
Query: 61 KLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVS 120
K D+ + + NVL + +++N++ QL K+K+ + + +L+ + + +
Sbjct: 535 KDMLDVKERKVNVL-----QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTT 589
Query: 121 LQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEV 180
L++AL + E LK EQ+ + ++ QEE + +K +++ LLQ E
Sbjct: 590 LEEALAEKERTIERLK------EQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEK 643
Query: 181 EEMIRDMGVGQS------------------AVEQLAVYCV----SLKKEYENLKEARKAS 218
E + D+ S A+EQ C+ LKK +E EAR AS
Sbjct: 644 EASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEAR-AS 702
Query: 219 GEVADK---LRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL 271
E++D+ L +++ + + +E+D+ LK + + DK+I L++++
Sbjct: 703 PEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQV 758
Score = 54.3 bits (129), Expect = 2e-07
Identities = 52/229 (22%), Positives = 108/229 (47%), Gaps = 23/229 (10%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQA 124
++ Q E ++F+KN++ V+ +LS+KD E Q ++TL + + + L+++
Sbjct: 422 EMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKES 481
Query: 125 LGKAEMLCSTLKKQMKYLEQQQDE--------TKQAQEEARRLRSKMKTMEQIELLLQSQ 176
L E + L+ ++ L + +E TKQ Q+ A ++ + ++ +L
Sbjct: 482 LTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML--- 538
Query: 177 RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLF------ 230
+V+E R + V Q +E L +K+ +LKE K+ AD D
Sbjct: 539 --DVKE--RKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSL--QADTTNTDTALTTLEE 592
Query: 231 SSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLN 279
+ K +T+ +Q + + Q+++ + K++ LK+K+++LQ L+
Sbjct: 593 ALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLS 641
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/242 (22%), Positives = 104/242 (42%), Gaps = 18/242 (7%)
Query: 82 ELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKY 141
E+D + L + + EK D I L ++++N V +L+ + + + ++ +
Sbjct: 729 EVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARR 788
Query: 142 LEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSA-------V 194
E +++ Q +++ LR K +E++E L+ E + +SA V
Sbjct: 789 REDNLNDSSQQLQDS--LRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQV 846
Query: 195 EQLAVYCVSLKKEYENLKEARKASGE-VADKLR--KDLFSSRSKLQTVYSELDQAKLELK 251
E+L + +K+E E++K ++ + +A+K +L + R K E+ Q L
Sbjct: 847 EELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAA 906
Query: 252 SAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRRPSFR 311
++KD A E+ S KKK T DRLV + + +KL ++
Sbjct: 907 ISEKDANIALLELSSSKKK------TQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYE 960
Query: 312 DD 313
DD
Sbjct: 961 DD 962
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/248 (21%), Positives = 112/248 (45%), Gaps = 46/248 (18%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQA 124
DL+++E ++LD LK ++ + +KD + TL LE++ + ++
Sbjct: 639 DLSEKEASLLD---LKEHASSLASSGLKKDSR-------LKTLEIALEQKKEECLKMESQ 688
Query: 125 LGKAEMLC------STLKKQMKYLEQQ----QDETKQAQEEARRLRSKMKTMEQIELLLQ 174
L KA + ++++LE++ +DE+ +AQ E RL +K +E +
Sbjct: 689 LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKD 748
Query: 175 SQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARK-------ASGEVADKLRK 227
+ E+E ++D + ++ V KK + L+EAR+ +S ++ D LRK
Sbjct: 749 KKIAELERQVKDQNKKVANLKHKEQ--VEKKKSAQMLEEARRREDNLNDSSQQLQDSLRK 806
Query: 228 ------DLFSSRSKLQTVYSELDQAKLELKSAQKD-----------LQSADKEIMSLKKK 270
+L + + + +E + + +SA+ + ++ +E+ S+K K
Sbjct: 807 KDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAK 866
Query: 271 LTMLQETL 278
L+ Q++L
Sbjct: 867 LSSTQQSL 874
Score = 29.3 bits (64), Expect = 8.0
Identities = 49/220 (22%), Positives = 86/220 (39%), Gaps = 17/220 (7%)
Query: 52 QVGKRTIINKLFFDLAQEEENV-LDAEFLKNELDNVRA--QLSQKDKEKRDSQVIIDTLR 108
+ K TI + + + +E +++ + + L++EL R QL Q+D R + + L
Sbjct: 204 EASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELT 263
Query: 109 DTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQ 168
E N + + E+ L+K ++ +E + + KQ K+ M Q
Sbjct: 264 ----EENFQRLHAEHERQAKELFL--LRKTLEEMELRIETQKQTLNARDESIKKLLEMLQ 317
Query: 169 IELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD 228
+ L E E R + + V L +KE L+E E A K
Sbjct: 318 SKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAK- 376
Query: 229 LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLK 268
LQTV D ++ S ++ L+ ++EI LK
Sbjct: 377 ----TKALQTVIEMKDS---KISSMERGLRDLEEEIQMLK 409
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 57.0 bits (136), Expect = 4e-08
Identities = 52/224 (23%), Positives = 103/224 (45%), Gaps = 17/224 (7%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L+ + ++ +A ++ +K+KRD ++ L+ LE+ T + Q+ K E + LKK
Sbjct: 1123 LQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKA 1182
Query: 139 MKYLEQQQDETKQAQEEARR-------LRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQ 191
++ E+ ++ Q Q+ +R L +++ ++ + L+ + +E +++
Sbjct: 1183 LE--EETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEV 1240
Query: 192 SAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELK 251
++Q+ +K+ + + A D+LR +L SKLQ +ELD L+
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQ---NELDNVSTLLE 1297
Query: 252 SAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLES 295
A+K K+ SL+ +L QE L ET +L L S
Sbjct: 1298 EAEKKGIKFAKDAASLESQLQDTQELLQ-----EETRQKLNLSS 1336
Score = 54.7 bits (130), Expect = 2e-07
Identities = 60/293 (20%), Positives = 131/293 (44%), Gaps = 26/293 (8%)
Query: 68 QEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGK 127
Q ++ D E L + D+V + + +K KR + ++ +R LEE + + + A +
Sbjct: 1505 QNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLR 1564
Query: 128 AEMLCSTLKKQMKYLEQQQDETKQAQ-----EEARRLRSKMKTMEQIELLLQSQRPEVEE 182
E+ +K Q + Q +DE + + ++ R L ++++ + L + + ++E
Sbjct: 1565 LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEI 1624
Query: 183 MIRDMGVGQSA--------VEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRS 234
++D+ A ++QL +K L+EAR + E+ + ++ S
Sbjct: 1625 DLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE----SEK 1680
Query: 235 KLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLT--------MLQETLNLPPVASE 286
KL+++ +E+ Q + EL S+++ + A++E L ++T +L E L ++
Sbjct: 1681 KLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ 1740
Query: 287 TVDRLVLESPAPVEVNLKLRRPSFRDDIDLNATFDVDTPPARPSSSQHGYYEK 339
+ L E +N + R+ + + D LNA + A+ S + E+
Sbjct: 1741 LEEELEEEQSNMELLNDRFRKTTLQVD-TLNAELAAERSAAQKSDNARQQLER 1792
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/236 (25%), Positives = 104/236 (44%), Gaps = 31/236 (13%)
Query: 76 AEFLKNELDNVRAQLSQKDKE----KRDSQVIIDTLRDTLEERNATVVSLQQALGKAEML 131
A L+NELDNV L + +K+ +D+ + L+DT Q+ L +
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT-----------QELLQEETRQ 1330
Query: 132 CSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQ 191
L +++ LE++++ ++ QEE R K +E+ L LQSQ + ++ + D
Sbjct: 1331 KLNLSSRIRQLEEEKNSLQEQQEEEEEAR---KNLEKQVLALQSQLADTKKKVDD---DL 1384
Query: 192 SAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELK 251
+E L L K+ E L + + DKL K ++++LQ ELD ++L
Sbjct: 1385 GTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEK----TKNRLQ---QELDDLTVDLD 1437
Query: 252 SAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRR 307
++ + +K+ KK +L E ++ +E DR E+ L L R
Sbjct: 1438 HQRQVASNLEKK---QKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLAR 1490
Score = 48.9 bits (115), Expect = 1e-05
Identities = 57/236 (24%), Positives = 107/236 (45%), Gaps = 35/236 (14%)
Query: 69 EEENVLDAEF-----LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQ 123
EE+N+L + L E + +RA+L+ K K++ + I+ L +EE LQ
Sbjct: 887 EEKNILAEQLQAETELFAEAEEMRARLAAK---KQELEEILHDLESRVEEEEERNQILQN 943
Query: 124 ALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPE---- 179
K + L++Q L++++ ++ Q E +K+K ME+ LLL+ Q +
Sbjct: 944 EKKKMQAHIQDLEEQ---LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKE 1000
Query: 180 ---VEEMIRDMGVGQSAVEQLAVYCVSLKKEYE--------NLKEARKASGEVADKLRKD 228
+E+ I + + E+ A ++ + E LK+ K E+ +K ++
Sbjct: 1001 KKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQEL-EKAKRK 1059
Query: 229 LFSSRSKLQTVYSEL----DQAKLELKSAQKDLQSA----DKEIMSLKKKLTMLQE 276
L + LQ +EL D+ KL+L +++LQ A D E + L +++E
Sbjct: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRE 1115
Score = 42.7 bits (99), Expect = 7e-04
Identities = 47/226 (20%), Positives = 103/226 (45%), Gaps = 16/226 (7%)
Query: 65 DLAQEEENVLDAEF-LKNELDNVRAQLSQKDKEKRDSQ------VIIDTLRDTLEERNAT 117
+L E + DA+ L+ + ++AQ ++D + RD Q ++I +R+ E
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQAMKAQF-ERDLQTRDEQNEEKKRLLIKQVREL--EAELE 1606
Query: 118 VVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEE-ARRLRSKMKTMEQIELLLQSQ 176
Q+AL A ++ +K LE Q + +A++E ++LR M+ + L+
Sbjct: 1607 DERKQRALAVASK--KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEA 1664
Query: 177 RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
R +E+ + ++ L + L++E + + AR+ + + D+L ++ +S S
Sbjct: 1665 RASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGK 1724
Query: 237 QTVYSELDQAKLELKSAQKDLQSADKEIMSLK---KKLTMLQETLN 279
+ E + + + +++L+ + L +K T+ +TLN
Sbjct: 1725 SALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLN 1770
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/267 (19%), Positives = 119/267 (44%), Gaps = 38/267 (14%)
Query: 79 LKNELDNVRAQLSQKDKE--------------KRDSQVIIDTLRDTLEERNATVVSLQQA 124
L+ ++D ++ QL++K++E K ++ ++ L+ + E S + +
Sbjct: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133
Query: 125 LGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM-KTMEQIELLLQSQRPEVEEM 183
KAE L ++++ L+ + ++T + LR+K + + +++ L+ + E
Sbjct: 1134 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ 1193
Query: 184 IRDMGVGQ-SAVEQLAVYCVSLKKEYENLKEARKA----SGEVA-------------DKL 225
I+DM +A+E+L+ K+ NL++ ++ + E+A +
Sbjct: 1194 IQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK 1253
Query: 226 RKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSL-----KKKLTMLQETLNL 280
RK L + +L SE D+ ++EL LQ+ + +L KK + ++ +L
Sbjct: 1254 RKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASL 1313
Query: 281 PPVASETVDRLVLESPAPVEVNLKLRR 307
+T + L E+ + ++ ++R+
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQ 1340
Score = 40.8 bits (94), Expect = 0.003
Identities = 45/259 (17%), Positives = 106/259 (40%), Gaps = 19/259 (7%)
Query: 68 QEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGK 127
Q+EE + L+ ++ +++QL+ K+ D I++L + ++ +L Q L +
Sbjct: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
Query: 128 AEMLCSTLKKQMKYLEQQQDETK----QAQEEARRLRSKMKTMEQ-------IELLLQSQ 176
+ L+K L+Q+ D+ ++ A L K K +Q I +
Sbjct: 1411 KALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEE 1470
Query: 177 RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGE----VADKLRKDLFSS 232
R E R+ ++ + + K+E+E + +A E D + K++
Sbjct: 1471 RDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHEL 1530
Query: 233 RSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL----TMLQETLNLPPVASETV 288
+ + ++++ + +L+ + +LQ+ + + L+ + + L +E
Sbjct: 1531 EKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEK 1590
Query: 289 DRLVLESPAPVEVNLKLRR 307
RL+++ +E L+ R
Sbjct: 1591 KRLLIKQVRELEAELEDER 1609
Score = 40.8 bits (94), Expect = 0.003
Identities = 48/240 (20%), Positives = 99/240 (41%), Gaps = 25/240 (10%)
Query: 65 DLAQEEENVLDAEFLKNEL-DNVRAQLSQKDK---EKRDSQVIIDTLRDTLEERNATVVS 120
+LA E AE ++EL D + S K EKR + I L + LEE + +
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
Query: 121 LQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKT-MEQIELLLQSQRPE 179
L K + TL ++ ++ A+++ R ++K ++++E ++S+
Sbjct: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK--- 1811
Query: 180 VEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEV---ADKLRKDLF----SS 232
++ + L L+++ E + R A+ ++ +K K++F
Sbjct: 1812 ----------FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDE 1861
Query: 233 RSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLV 292
R ++++A +K ++ L+ A++E LQ L+ A+E + R V
Sbjct: 1862 RRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREV 1921
Score = 38.9 bits (89), Expect = 0.010
Identities = 44/203 (21%), Positives = 92/203 (45%), Gaps = 21/203 (10%)
Query: 59 INKLFFDLAQEEENV--LDAEFLKNEL--DNVRAQLSQKDKEKRDSQVIIDTLRDTLEER 114
I +L +L +E+ N+ L+ F K L D + A+L+ + + S D R LE +
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS----DNARQQLERQ 1793
Query: 115 NATVVSLQQAL-----GKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRL-RSKMKTMEQ 168
N + + Q L K + S L+ ++ LE+Q ++ + + A +L R K +++
Sbjct: 1794 NKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKE 1853
Query: 169 IELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD 228
I + ++ +R ++ M + ++QL K++ E +E + KL+++
Sbjct: 1854 IFMQVEDERRHADQYKEQMEKANARMKQL-------KRQLEEAEEEATRANASRRKLQRE 1906
Query: 229 LFSSRSKLQTVYSELDQAKLELK 251
L + + + E+ K L+
Sbjct: 1907 LDDATEANEGLSREVSTLKNRLR 1929
Score = 35.8 bits (81), Expect = 0.086
Identities = 24/144 (16%), Positives = 74/144 (51%), Gaps = 4/144 (2%)
Query: 137 KQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQ 196
+Q + L+ + +E + +E+ ++ +++ ME+ L ++ + E ++ + E+
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEE 908
Query: 197 LAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKD 256
+ + K+E E + ++ E ++ + L + + K+Q +L++ E + A++
Sbjct: 909 MRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQK 968
Query: 257 LQ----SADKEIMSLKKKLTMLQE 276
LQ +A+ +I +++++ +L++
Sbjct: 969 LQLEKVTAEAKIKKMEEEILLLED 992
Score = 30.0 bits (66), Expect = 4.7
Identities = 34/157 (21%), Positives = 78/157 (49%), Gaps = 16/157 (10%)
Query: 90 LSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDET 149
L Q +++ + Q + L E++ L++ K + L L+++ EQ Q ET
Sbjct: 844 LLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQL---LEEKNILAEQLQAET 900
Query: 150 K---QAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKK 206
+ +A+E RL +K + +E+I L+S+ E EE + + Q+ +++ + L++
Sbjct: 901 ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQ---ILQNEKKKMQAHIQDLEE 957
Query: 207 EYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSEL 243
+ + + AR+ KL+ + ++ +K++ + E+
Sbjct: 958 QLDEEEGARQ-------KLQLEKVTAEAKIKKMEEEI 987
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 57.0 bits (136), Expect = 4e-08
Identities = 53/225 (23%), Positives = 107/225 (47%), Gaps = 36/225 (16%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L ++DN++ + +KEK + ++ ID L +E ++ +A G E +C TL+ Q
Sbjct: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVE-------TVSKAKGNLEKMCRTLEDQ 1261
Query: 139 MKYLEQQQDETK---------------QAQEEARRLRSKMKTMEQIELLLQSQRPEVEEM 183
+ L+ +++E + ++ E +R+L K + Q+ Q+ ++EE+
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321
Query: 184 IRDMGVGQSAVEQLAVY-------CVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
R + A LA C L+++YE +E++ K ++ R+K
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381
Query: 237 QT----VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQET 277
+T EL++AK +L AQ+ LQ+A++ + ++ K L++T
Sbjct: 1382 ETDAIQRTEELEEAKKKL--AQR-LQAAEEHVEAVNAKCASLEKT 1423
Score = 48.9 bits (115), Expect = 1e-05
Identities = 54/249 (21%), Positives = 109/249 (43%), Gaps = 25/249 (10%)
Query: 60 NKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVV 119
N L + E E + DAE ++L + QL K KE + + EE NA +
Sbjct: 891 NDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKE-------VTERAEDEEEINAELT 943
Query: 120 SLQQALGKAEMLCSTLKKQMKYLE----QQQDETKQAQEEARRLRSKMKTMEQIELLLQS 175
+ ++ K E CS LKK + LE + + E + + + L +M +++ L
Sbjct: 944 AKKR---KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK 1000
Query: 176 QRPEVEE----MIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFS 231
++ ++E + D+ + V L + L+++ ++L + S E KLR DL
Sbjct: 1001 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL----EGSLEQEKKLRMDLER 1056
Query: 232 SRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRL 291
++ KL+ +L A+ + + + Q D+++ + +++ LQ + + +
Sbjct: 1057 AKRKLE---GDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKK 1113
Query: 292 VLESPAPVE 300
+ E A +E
Sbjct: 1114 IKELQARIE 1122
Score = 48.1 bits (113), Expect = 2e-05
Identities = 54/236 (22%), Positives = 106/236 (44%), Gaps = 23/236 (9%)
Query: 61 KLFFDLAQEEENVLDAEFLKNELDNV----RAQLSQKDKEKRDSQVIIDTLRDTLEERNA 116
KL DL +E+++D E K +LD ++S + D Q + L+ ++E A
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119
Query: 117 TVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQ 176
+ L++ + + +KQ L ++ +E + EEA T QIE + + +
Sbjct: 1120 RIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG-----ATSAQIE-MNKKR 1173
Query: 177 RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
E ++M RD+ ++ ++ A KK +++ E GE D L++ + KL
Sbjct: 1174 EAEFQKMRRDL--EEATLQHEATAATLRKKHADSVAEL----GEQIDNLQR----VKQKL 1223
Query: 237 QTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLV 292
+ SE+ K+E+ ++++ K +L+K L++ L+ E RL+
Sbjct: 1224 EKEKSEM---KMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Score = 47.4 bits (111), Expect = 3e-05
Identities = 53/259 (20%), Positives = 120/259 (46%), Gaps = 22/259 (8%)
Query: 82 ELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKY 141
+LD A +SQ + K+ I+ L+ LEE +L AL + C L++Q +
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355
Query: 142 LEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPE--VEEMIRDMGVGQSAVEQLAV 199
++ + E ++A +A ++ +T + + + +++ E +++ + + + VE +
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
Query: 200 YCVSLKKEYENLK----------EARKASGEVADKLRKD----LFSSRSKLQTVYSELDQ 245
C SL+K + L+ E A+ DK +++ L + K + ++EL+
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475
Query: 246 AKLELKSAQKDL---QSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVN 302
++ E +S +L ++A +E SL + T+ +E NL S+ ++ + E +
Sbjct: 1476 SQKEARSLGTELFKIKNAYEE--SLDQLETLKRENKNLQQEISDLTEQ-IAEGGKRIHEL 1532
Query: 303 LKLRRPSFRDDIDLNATFD 321
K+++ ++ +L A +
Sbjct: 1533 EKIKKQVEQEKCELQAALE 1551
Score = 42.4 bits (98), Expect = 0.001
Identities = 51/250 (20%), Positives = 106/250 (42%), Gaps = 16/250 (6%)
Query: 44 RTCPQCRIQVGKRTIINKLFFDLAQE-EENVLDAEFLKNELDNVRAQLSQKDKEKRDSQV 102
RT C K+ +K+ + Q+ EE + E + E ++ +L + +S
Sbjct: 1440 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLD 1499
Query: 103 IIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEAR-RLRS 161
++TL+ + + L + + + L+K K +EQ++ E + A EEA L
Sbjct: 1500 QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEH 1559
Query: 162 KMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEV 221
+ + +I+L L + EV+ I + ++QL + + + ++ +A S
Sbjct: 1560 EEGKILRIQLELNQVKSEVDRKIAEK---DEEIDQLKRNHIRIVESMQSTLDAEIRSRND 1616
Query: 222 ADKLRKDLFSSRSKLQTVYSELDQAKLE-----------LKSAQKDLQSADKEIMSLKKK 270
A +L+K + ++++ + ++ E LK Q L A + LK++
Sbjct: 1617 AIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQ 1676
Query: 271 LTMLQETLNL 280
L M++ NL
Sbjct: 1677 LAMVERRANL 1686
Score = 41.2 bits (95), Expect = 0.002
Identities = 50/248 (20%), Positives = 112/248 (45%), Gaps = 42/248 (16%)
Query: 61 KLFFD---LAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNAT 117
KLFF L + E + +K E ++ +L++ + ++++ + + TL L+E+N
Sbjct: 837 KLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTL---LKEKNDL 893
Query: 118 VVSLQ---QALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM----------- 163
+ +Q + L AE C L K LE + E + E+ + +++
Sbjct: 894 QLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDEC 953
Query: 164 ----KTMEQIELLL---QSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARK 216
K ++ +EL L + ++ E ++++ + +++ L KE + L+EA +
Sbjct: 954 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIA---KLTKEKKALQEAHQ 1010
Query: 217 ASGEVADKLRKD------LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
+ D L+ + L ++ KL+ +L+ + + K + DL+ A ++ L+
Sbjct: 1011 ---QTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRK---LEGD 1064
Query: 271 LTMLQETL 278
L + QE++
Sbjct: 1065 LKLAQESI 1072
Score = 39.7 bits (91), Expect = 0.006
Identities = 48/232 (20%), Positives = 99/232 (42%), Gaps = 16/232 (6%)
Query: 70 EENVLDAEFLKNELDNVRAQL-SQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKA 128
E+ +LDA L L + K K + D + + D L+E ++A+ A
Sbjct: 1709 EQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDA 1768
Query: 129 EMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELL-LQSQRPEVEEMIRDM 187
M+ LKK+ + K ++ + L+ ++ EQ+ L + Q ++E +R++
Sbjct: 1769 AMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVREL 1828
Query: 188 GVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAK 247
G+ EQ K+ E +K RK V + L R + + +D+ +
Sbjct: 1829 -EGEVESEQ--------KRNAEAVKGLRKHERRVKE-LTYQTEEDRKNILRLQDLVDKLQ 1878
Query: 248 LELKSAQKDLQSADKE----IMSLKKKLTMLQETLNLPPVASETVDRLVLES 295
++KS ++ + A+++ + +K L+E +A V++L ++S
Sbjct: 1879 AKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKS 1930
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 57.0 bits (136), Expect = 4e-08
Identities = 53/225 (23%), Positives = 107/225 (47%), Gaps = 36/225 (16%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L ++DN++ + +KEK + ++ ID L +E ++ +A G E +C TL+ Q
Sbjct: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVE-------TVSKAKGNLEKMCRTLEDQ 1261
Query: 139 MKYLEQQQDETK---------------QAQEEARRLRSKMKTMEQIELLLQSQRPEVEEM 183
+ L+ +++E + ++ E +R+L K + Q+ Q+ ++EE+
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321
Query: 184 IRDMGVGQSAVEQLAVY-------CVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
R + A LA C L+++YE +E++ K ++ R+K
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381
Query: 237 QT----VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQET 277
+T EL++AK +L AQ+ LQ+A++ + ++ K L++T
Sbjct: 1382 ETDAIQRTEELEEAKKKL--AQR-LQAAEEHVEAVNAKCASLEKT 1423
Score = 48.9 bits (115), Expect = 1e-05
Identities = 54/249 (21%), Positives = 109/249 (43%), Gaps = 25/249 (10%)
Query: 60 NKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVV 119
N L + E E + DAE ++L + QL K KE + + EE NA +
Sbjct: 891 NDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKE-------VTERAEDEEEINAELT 943
Query: 120 SLQQALGKAEMLCSTLKKQMKYLE----QQQDETKQAQEEARRLRSKMKTMEQIELLLQS 175
+ ++ K E CS LKK + LE + + E + + + L +M +++ L
Sbjct: 944 AKKR---KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK 1000
Query: 176 QRPEVEE----MIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFS 231
++ ++E + D+ + V L + L+++ ++L + S E KLR DL
Sbjct: 1001 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL----EGSLEQEKKLRMDLER 1056
Query: 232 SRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRL 291
++ KL+ +L A+ + + + Q D+++ + +++ LQ + + +
Sbjct: 1057 AKRKLE---GDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKK 1113
Query: 292 VLESPAPVE 300
+ E A +E
Sbjct: 1114 IKELQARIE 1122
Score = 48.1 bits (113), Expect = 2e-05
Identities = 54/236 (22%), Positives = 106/236 (44%), Gaps = 23/236 (9%)
Query: 61 KLFFDLAQEEENVLDAEFLKNELDNV----RAQLSQKDKEKRDSQVIIDTLRDTLEERNA 116
KL DL +E+++D E K +LD ++S + D Q + L+ ++E A
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119
Query: 117 TVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQ 176
+ L++ + + +KQ L ++ +E + EEA T QIE + + +
Sbjct: 1120 RIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG-----ATSAQIE-MNKKR 1173
Query: 177 RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
E ++M RD+ ++ ++ A KK +++ E GE D L++ + KL
Sbjct: 1174 EAEFQKMRRDL--EEATLQHEATAATLRKKHADSVAEL----GEQIDNLQR----VKQKL 1223
Query: 237 QTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLV 292
+ SE+ K+E+ ++++ K +L+K L++ L+ E RL+
Sbjct: 1224 EKEKSEM---KMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Score = 47.4 bits (111), Expect = 3e-05
Identities = 53/259 (20%), Positives = 120/259 (46%), Gaps = 22/259 (8%)
Query: 82 ELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKY 141
+LD A +SQ + K+ I+ L+ LEE +L AL + C L++Q +
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355
Query: 142 LEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPE--VEEMIRDMGVGQSAVEQLAV 199
++ + E ++A +A ++ +T + + + +++ E +++ + + + VE +
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415
Query: 200 YCVSLKKEYENLK----------EARKASGEVADKLRKD----LFSSRSKLQTVYSELDQ 245
C SL+K + L+ E A+ DK +++ L + K + ++EL+
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475
Query: 246 AKLELKSAQKDL---QSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVN 302
++ E +S +L ++A +E SL + T+ +E NL S+ ++ + E +
Sbjct: 1476 SQKEARSLGTELFKIKNAYEE--SLDQLETLKRENKNLQQEISDLTEQ-IAEGGKRIHEL 1532
Query: 303 LKLRRPSFRDDIDLNATFD 321
K+++ ++ +L A +
Sbjct: 1533 EKIKKQVEQEKCELQAALE 1551
Score = 42.4 bits (98), Expect = 0.001
Identities = 51/250 (20%), Positives = 106/250 (42%), Gaps = 16/250 (6%)
Query: 44 RTCPQCRIQVGKRTIINKLFFDLAQE-EENVLDAEFLKNELDNVRAQLSQKDKEKRDSQV 102
RT C K+ +K+ + Q+ EE + E + E ++ +L + +S
Sbjct: 1440 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLD 1499
Query: 103 IIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEAR-RLRS 161
++TL+ + + L + + + L+K K +EQ++ E + A EEA L
Sbjct: 1500 QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEH 1559
Query: 162 KMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEV 221
+ + +I+L L + EV+ I + ++QL + + + ++ +A S
Sbjct: 1560 EEGKILRIQLELNQVKSEVDRKIAEK---DEEIDQLKRNHIRIVESMQSTLDAEIRSRND 1616
Query: 222 ADKLRKDLFSSRSKLQTVYSELDQAKLE-----------LKSAQKDLQSADKEIMSLKKK 270
A +L+K + ++++ + ++ E LK Q L A + LK++
Sbjct: 1617 AIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQ 1676
Query: 271 LTMLQETLNL 280
L M++ NL
Sbjct: 1677 LAMVERRANL 1686
Score = 41.2 bits (95), Expect = 0.002
Identities = 50/248 (20%), Positives = 112/248 (45%), Gaps = 42/248 (16%)
Query: 61 KLFFD---LAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNAT 117
KLFF L + E + +K E ++ +L++ + ++++ + + TL L+E+N
Sbjct: 837 KLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTL---LKEKNDL 893
Query: 118 VVSLQ---QALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM----------- 163
+ +Q + L AE C L K LE + E + E+ + +++
Sbjct: 894 QLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDEC 953
Query: 164 ----KTMEQIELLL---QSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARK 216
K ++ +EL L + ++ E ++++ + +++ L KE + L+EA +
Sbjct: 954 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIA---KLTKEKKALQEAHQ 1010
Query: 217 ASGEVADKLRKD------LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
+ D L+ + L ++ KL+ +L+ + + K + DL+ A ++ L+
Sbjct: 1011 ---QTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRK---LEGD 1064
Query: 271 LTMLQETL 278
L + QE++
Sbjct: 1065 LKLAQESI 1072
Score = 39.7 bits (91), Expect = 0.006
Identities = 48/232 (20%), Positives = 99/232 (42%), Gaps = 16/232 (6%)
Query: 70 EENVLDAEFLKNELDNVRAQL-SQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKA 128
E+ +LDA L L + K K + D + + D L+E ++A+ A
Sbjct: 1709 EQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDA 1768
Query: 129 EMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELL-LQSQRPEVEEMIRDM 187
M+ LKK+ + K ++ + L+ ++ EQ+ L + Q ++E +R++
Sbjct: 1769 AMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVREL 1828
Query: 188 GVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAK 247
G+ EQ K+ E +K RK V + L R + + +D+ +
Sbjct: 1829 -EGEVESEQ--------KRNAEAVKGLRKHERRVKE-LTYQTEEDRKNILRLQDLVDKLQ 1878
Query: 248 LELKSAQKDLQSADKE----IMSLKKKLTMLQETLNLPPVASETVDRLVLES 295
++KS ++ + A+++ + +K L+E +A V++L ++S
Sbjct: 1879 AKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKS 1930
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 56.6 bits (135), Expect = 5e-08
Identities = 57/226 (25%), Positives = 113/226 (50%), Gaps = 37/226 (16%)
Query: 74 LDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCS 133
++ + L+ L+N ++ Q + E +D ++ TL+ LEE + L+Q
Sbjct: 763 IENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQ---------- 812
Query: 134 TLKKQMKYLEQQ----QDETKQAQEEARRLRS----KMKTMEQIELLLQSQRPEVEEMIR 185
L+K+ K LEQ+ + + KQ ++E +RLR K T+E+ + + + E + + +
Sbjct: 813 -LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Query: 186 DMGVGQSAVEQLAVYCVSLKK-EYENLKEARKASGEVAD--KLRKDLFSSRSKLQTVYSE 242
++G+ + + CV LK+ E EN + ++A+ ++ LR+DL S + K Q + ++
Sbjct: 872 EIGIYKES-------CVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNND 924
Query: 243 LDQAKLELKS-------AQKDLQSADKEIMSLKKKL-TMLQETLNL 280
L++ EL+ D QS D L+ KL + L+++L +
Sbjct: 925 LEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEI 970
Score = 50.1 bits (118), Expect = 4e-06
Identities = 55/223 (24%), Positives = 105/223 (47%), Gaps = 18/223 (8%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQA 124
+L +E AE L+NEL ++ + K+ + ++ + + + LE+ N+ L++
Sbjct: 616 ELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI-EALEQENS---ELERE 671
Query: 125 LGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMI 184
K + + K LE + E Q EE LR +++++ + + + E +E+
Sbjct: 672 NRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKEL- 730
Query: 185 RDMGVGQSAVEQLAVYCVSLK---KEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYS 241
+S EQL LK K+ E L+ + + +L+K L +S K+Q + S
Sbjct: 731 ------ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 242 ELDQAKLELKSAQKDLQS---ADKEIMSLKKKLTML-QETLNL 280
EL ++E ++ QK+L+ + K + L+K+ L QET L
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQL 827
Score = 47.0 bits (110), Expect = 4e-05
Identities = 52/227 (22%), Positives = 102/227 (44%), Gaps = 14/227 (6%)
Query: 106 TLRDTLEERNATVVSLQ---QALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRL-RS 161
+L T+EE TV S++ + K E L K+++ LE + + KQ+ + + L +
Sbjct: 471 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 530
Query: 162 KMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEV 221
MK Q+E +++ R E I+ + + E L SL++ + EAR E
Sbjct: 531 LMKEKAQLEKTIETLRENSERQIKIL---EQENEHLNQTVSSLRQRSQISAEARVKDIEK 587
Query: 222 ADKLR----KDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQET 277
+K+ K+ S SK++ ++ + K + + + E+ L+K+ +LQ+
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Query: 278 LNLPPVASETVDRLVLESPAPVEVNLKLRRPSFRDDIDLNATFDVDT 324
+ + E ++ L E+ N KL++ D N TF +++
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTL---DSFKNLTFQLES 691
Score = 43.1 bits (100), Expect = 5e-04
Identities = 58/241 (24%), Positives = 117/241 (48%), Gaps = 32/241 (13%)
Query: 76 AEFLKNELDNVRAQLSQKDK--------EKRDSQVIIDTLRDTLEERNATVVSLQQALGK 127
++ LK E +N R LS+K + EK+ Q + +D ++E+ L++ +
Sbjct: 491 SKILKMEKENQR--LSKKVEILENEIVQEKQSLQNCQNLSKDLMKEK----AQLEKTI-- 542
Query: 128 AEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDM 187
E L ++Q+K LEQ+ + Q R+ RS++ +++ + + + + E I++
Sbjct: 543 -ETLRENSERQIKILEQENEHLNQTVSSLRQ-RSQISAEARVKDI-EKENKILHESIKET 599
Query: 188 GVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAK 247
S + ++ +KKE E+ KE GE A++L +L + +EL Q K
Sbjct: 600 S---SKLSKIEFEKRQIKKELEHYKE----KGERAEELENELHHLEKE-----NELLQKK 647
Query: 248 L-ELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLR 306
+ LK + +++ ++E L+++ L++TL+ + ++ L E+ E NL+LR
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Query: 307 R 307
R
Sbjct: 708 R 708
Score = 32.3 bits (72), Expect = 0.95
Identities = 40/210 (19%), Positives = 86/210 (40%), Gaps = 47/210 (22%)
Query: 75 DAEFLKNELDNV--------RAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALG 126
D E L +EL+ + + S D+ K + TL+ +LE + + +L+ L
Sbjct: 924 DLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLE 983
Query: 127 KAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRD 186
++ L++++K +++ + KQ Q+E R ++QS P E
Sbjct: 984 ESTNYNQQLRQELKTVKKNYEALKQRQDEER--------------MVQSSPPISGE---- 1025
Query: 187 MGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQA 246
++E +E+++ + E+ K++ L T+ +E
Sbjct: 1026 ------------------DNKWE--RESQETTRELL-KVKDRLIEVERNNATLQAEKQAL 1064
Query: 247 KLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
K +LK + + +I++L+++ LQE
Sbjct: 1065 KTQLKQLETQNNNLQAQILALQRQTVSLQE 1094
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 55.5 bits (132), Expect = 1e-07
Identities = 52/225 (23%), Positives = 105/225 (46%), Gaps = 36/225 (16%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L ++DN++ + +KEK + ++ ID L +E ++ +A G E +C L+ Q
Sbjct: 1207 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNME-------TVSKAKGNLEKMCRALEDQ 1259
Query: 139 MKYLEQQQDETK---------------QAQEEARRLRSKMKTMEQIELLLQSQRPEVEEM 183
+ ++ +++E + ++ E +R+L K + Q+ Q+ ++EE+
Sbjct: 1260 LSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEEL 1319
Query: 184 IRDMGVGQSAVEQLAVY-------CVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
R + A LA C L+++YE +EA+ K ++ R+K
Sbjct: 1320 KRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKY 1379
Query: 237 QT----VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQET 277
+T EL++AK +L AQ+ LQ A++ + ++ K L++T
Sbjct: 1380 ETDAIQRTEELEEAKKKL--AQR-LQDAEEHVEAVNAKCASLEKT 1421
Score = 48.5 bits (114), Expect = 1e-05
Identities = 39/204 (19%), Positives = 90/204 (44%), Gaps = 9/204 (4%)
Query: 77 EFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLK 136
E L+ E++ RA ++ +K++ D ++ + + LEE + + K E ++
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
Query: 137 KQMKYLEQQQDET-----KQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQ 191
+ ++ Q + T K+ + L ++ +++++ L+ ++ E++ I D+
Sbjct: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239
Query: 192 SAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSE----LDQAK 247
V + + + E+ K E +L DL + R++LQT E LD+
Sbjct: 1240 ETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKD 1299
Query: 248 LELKSAQKDLQSADKEIMSLKKKL 271
+ + Q+ ++I LK++L
Sbjct: 1300 TLVSQLSRGKQAFTQQIEELKRQL 1323
Score = 47.8 bits (112), Expect = 2e-05
Identities = 53/249 (21%), Positives = 109/249 (43%), Gaps = 25/249 (10%)
Query: 60 NKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVV 119
N L + E +++ DAE ++L + QL K KE + + EE NA +
Sbjct: 889 NDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKE-------VTERAEDEEEINAELT 941
Query: 120 SLQQALGKAEMLCSTLKKQMKYLE----QQQDETKQAQEEARRLRSKMKTMEQIELLLQS 175
+ ++ K E CS LKK + LE + + E + + + L +M +++ L
Sbjct: 942 AKKR---KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK 998
Query: 176 QRPEVEE----MIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFS 231
++ ++E + D+ + V L + L+++ ++L + S E K+R DL
Sbjct: 999 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL----EGSLEQEKKIRMDLER 1054
Query: 232 SRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRL 291
++ KL+ +L A+ + D Q D+++ + +++ LQ + + +
Sbjct: 1055 AKRKLE---GDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKK 1111
Query: 292 VLESPAPVE 300
+ E A +E
Sbjct: 1112 IKELQARIE 1120
Score = 47.0 bits (110), Expect = 4e-05
Identities = 54/236 (22%), Positives = 105/236 (44%), Gaps = 23/236 (9%)
Query: 61 KLFFDLAQEEENVLDAEFLKNELDNV----RAQLSQKDKEKRDSQVIIDTLRDTLEERNA 116
KL DL +E+ +D E K +LD ++S + D Q + L+ ++E A
Sbjct: 1058 KLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQA 1117
Query: 117 TVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQ 176
+ L++ + + +KQ L ++ +E + EEA T QIE + + +
Sbjct: 1118 RIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG-----ATSAQIE-MNKKR 1171
Query: 177 RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
E ++M RD+ ++ ++ A KK +++ E GE D L++ + KL
Sbjct: 1172 EAEFQKMRRDL--EEATLQHEATAATLRKKHADSVAEL----GEQIDNLQR----VKQKL 1221
Query: 237 QTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLV 292
+ SE+ K+E+ ++++ K +L+K L++ L+ E RL+
Sbjct: 1222 EKEKSEM---KMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLI 1274
Score = 44.7 bits (104), Expect = 2e-04
Identities = 48/229 (20%), Positives = 107/229 (46%), Gaps = 21/229 (9%)
Query: 82 ELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKY 141
+LD +SQ + K+ I+ L+ LEE +L AL + C L++Q +
Sbjct: 1294 QLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE 1353
Query: 142 LEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPE--VEEMIRDMGVGQSAVEQLAV 199
++ + E ++A +A ++ +T + + + +++ E +++ + + + VE +
Sbjct: 1354 EQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNA 1413
Query: 200 YCVSLKKEYENLK----------EARKASGEVADKLRKD----LFSSRSKLQTVYSELDQ 245
C SL+K + L+ E A+ DK +++ L + K + ++EL+
Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1473
Query: 246 AKLELKSAQKDL---QSADKEIMSLKKKLTMLQETLNLPPVASETVDRL 291
++ E +S +L ++A +E SL + T+ +E NL S+ +++
Sbjct: 1474 SQKESRSLSTELFKIKNAYEE--SLDQLETLKRENKNLQQEISDLTEQI 1520
Score = 43.1 bits (100), Expect = 5e-04
Identities = 50/250 (20%), Positives = 106/250 (42%), Gaps = 16/250 (6%)
Query: 44 RTCPQCRIQVGKRTIINKLFFDLAQE-EENVLDAEFLKNELDNVRAQLSQKDKEKRDSQV 102
RT C K+ +K+ + Q+ EE + E + E ++ +L + +S
Sbjct: 1438 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLD 1497
Query: 103 IIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEAR-RLRS 161
++TL+ + + L + + + L+K K +EQ++ E + A EEA L
Sbjct: 1498 QLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEH 1557
Query: 162 KMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEV 221
+ + +I+L L + EV+ I + ++Q+ + + + ++ +A S
Sbjct: 1558 EEGKILRIQLELNQVKSEVDRKIAEK---DEEIDQMKRNHIRIVESMQSTLDAEIRSRND 1614
Query: 222 ADKLRKDLFSSRSKLQTVYSELDQAKLE-----------LKSAQKDLQSADKEIMSLKKK 270
A +L+K + ++++ + ++ E LK Q L A + LK++
Sbjct: 1615 AIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQ 1674
Query: 271 LTMLQETLNL 280
L M++ NL
Sbjct: 1675 LAMVERRANL 1684
Score = 41.6 bits (96), Expect = 0.002
Identities = 28/144 (19%), Positives = 72/144 (50%), Gaps = 6/144 (4%)
Query: 140 KYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAV 199
K + ++E ++ +EE + +K K +E+ + L ++ +++ ++ + E+
Sbjct: 851 KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCD 910
Query: 200 YCVSLKKEYE-NLKEARKASGEVADKLRKDLFSSRSKLQTVYSEL----DQAKLELKSAQ 254
+ K + E +KE + + E +++ +L + + KL+ SEL D +L L +
Sbjct: 911 QLIKTKIQLEAKIKEVTERA-EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 255 KDLQSADKEIMSLKKKLTMLQETL 278
K+ + + ++ +L +++ L ET+
Sbjct: 970 KEKHATENKVKNLTEEMAGLDETI 993
Score = 39.7 bits (91), Expect = 0.006
Identities = 47/232 (20%), Positives = 100/232 (43%), Gaps = 16/232 (6%)
Query: 70 EENVLDAEFLKNELDNVRAQL-SQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKA 128
E+ +LDA L L + K K + D I + D ++E ++A+ A
Sbjct: 1707 EQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDA 1766
Query: 129 EMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELL-LQSQRPEVEEMIRDM 187
M+ LKK+ + K ++ + L+ ++ EQ+ L + Q ++E +R++
Sbjct: 1767 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVREL 1826
Query: 188 GVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAK 247
G+ EQ K+ E +K RK +V + L R + + +D+ +
Sbjct: 1827 -EGEVESEQ--------KRNVEAVKGLRKHERKVKE-LTYQTEEDRKNILRLQDLVDKLQ 1876
Query: 248 LELKSAQKDLQSADKE----IMSLKKKLTMLQETLNLPPVASETVDRLVLES 295
++KS ++ + A+++ + ++ L+E +A V++L ++S
Sbjct: 1877 AKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKS 1928
Score = 38.5 bits (88), Expect = 0.013
Identities = 45/243 (18%), Positives = 106/243 (43%), Gaps = 36/243 (14%)
Query: 61 KLFFD---LAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNAT 117
KL+F L + E + +K E + + +L++ + ++++ + + TL +
Sbjct: 835 KLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQ 894
Query: 118 VVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM-------------- 163
V + +L AE C L K LE + E + E+ + +++
Sbjct: 895 VQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSEL 954
Query: 164 -KTMEQIELLL---QSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASG 219
K ++ +EL L + ++ E ++++ + +++ L KE + L+EA +
Sbjct: 955 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIA---KLTKEKKALQEAHQ--- 1008
Query: 220 EVADKLRKD------LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEI---MSLKKK 270
+ D L+ + L ++ KL+ +L+ + + K + DL+ A +++ + L ++
Sbjct: 1009 QTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQE 1068
Query: 271 LTM 273
TM
Sbjct: 1069 STM 1071
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 55.1 bits (131), Expect = 1e-07
Identities = 58/289 (20%), Positives = 120/289 (41%), Gaps = 42/289 (14%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQK-----------DKEKRDSQVIIDTLRDTLEE 113
DL Q +E++ AE + + D + +L+++ EKR + I L + LEE
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1747
Query: 114 RNATVVSL----QQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTME-- 167
+ ++ ++A +AE L + L + ++ + +Q + + + LRSK+ ME
Sbjct: 1748 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1807
Query: 168 -----------------QIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYEN 210
Q+E ++ + E + + + ++++ + +K E
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867
Query: 211 LKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
KE + +L++ L + + Q + + + + EL A + ++ +E+ +LK K
Sbjct: 1868 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
Query: 271 LTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRRPSFRDDIDLNAT 319
L ET +P + + R V+E+ E R D D N T
Sbjct: 1928 LRRGNETSFVP--SRRSGGRRVIENADGSEEETDTR------DADFNGT 1968
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/250 (22%), Positives = 111/250 (44%), Gaps = 32/250 (12%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L+ +LD+ RA ++ +K+KRD ++ L+ LE+ + + Q+ K E + LKK
Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA 1182
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLA 198
+ +ET+ + + + +R Q VEE+ + + A L
Sbjct: 1183 L------DEETRSHEAQVQEMR-------------QKHAQAVEELTEQLEQFKRAKANLD 1223
Query: 199 VYCVSLKKEYENLKEARKASGEVADKL---RKDLFSSRSKLQTVYSELDQAKLELKSAQK 255
+L+KE +L + G+ ++ +K L + +LQ+ S+ ++A+ EL
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283
Query: 256 DLQSADKEIMSL-----KKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLR---- 306
LQ+ + + + K + + ++ +L +T + L E+ + V+ KLR
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343
Query: 307 -RPSFRDDID 315
R S +D +D
Sbjct: 1344 ERNSLQDQLD 1353
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/297 (19%), Positives = 133/297 (44%), Gaps = 15/297 (5%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L+ E ++++ QL ++ + K++ + I TL L + + + E +K+
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKT-MEQIELLLQSQRPEVEEMIRDMGVGQSAVEQL 197
++ L QQ +E A ++ + +++++ ++ + + L +QR +++ ++ Q +QL
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR----QLVSNLEKKQRKFDQL 1456
Query: 198 AVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYS--ELDQAKLELKSAQK 255
++ +Y + E +A E +K K L +R+ + + + EL++ LK+ +
Sbjct: 1457 LAEEKNISSKYAD--ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514
Query: 256 DLQSA----DKEIMSLKKKLTMLQETL-NLPPVASETVDRLVLESPAPVEVNLKLRRPSF 310
DL S+ K + L+K L+ + + E D L A + + + ++
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1574
Query: 311 RDDIDLNATFDVDTPPARPSSSQ-HGYYEKLCLEKSHSPIQDVPKKICKGPRKESQL 366
+ + DL A + + R Q H Y +L E+ + KK +G K+ +L
Sbjct: 1575 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1631
Score = 44.3 bits (103), Expect = 2e-04
Identities = 54/255 (21%), Positives = 117/255 (45%), Gaps = 13/255 (5%)
Query: 59 INKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLE----ER 114
I+ L +LA+EEE + LKN+ +++ ++L + K++ S+ ++ L+ LE +
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067
Query: 115 NATVVSLQQALGKAEMLCSTLKKQMK-YLEQQQDETKQAQEEARRLRSKMKTMEQIELLL 173
+ + LQ + + +M + +++++ L + DE Q +++R + ++ L
Sbjct: 1068 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1127
Query: 174 QSQRP---EVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADK-LRKDL 229
S+R + E+ RD+G A++ + + L+ R+ V K L ++
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1187
Query: 230 FSSRSKLQTVYSELDQAKLELKSAQKDLQSA----DKEIMSLKKKLTMLQETLNLPPVAS 285
S +++Q + + QA EL + + A DK +L+K+ L L + A
Sbjct: 1188 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1247
Query: 286 ETVDRLVLESPAPVE 300
+ V+ + A V+
Sbjct: 1248 QEVEHKKKKLEAQVQ 1262
Score = 43.1 bits (100), Expect = 5e-04
Identities = 28/147 (19%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Query: 137 KQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQ 196
+Q + ++ ++DE ++ +E ++ +++K +EQ L ++ ++E ++ + E+
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908
Query: 197 LAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKD 256
+ V + K+E E + +A E + + L + R K+ +L++ E ++A++
Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968
Query: 257 LQ----SADKEIMSLKKKLTMLQETLN 279
LQ +A+ +I L+ ++ ++ + N
Sbjct: 969 LQLEKVTAEAKIKKLEDEILVMDDQNN 995
Score = 40.4 bits (93), Expect = 0.003
Identities = 57/251 (22%), Positives = 106/251 (42%), Gaps = 32/251 (12%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
++++ + AQ+ + + D + L D + + V S+ L +AE L K
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 139 MKYLEQQQDETKQA-QEEARR---LRSKMKTMEQIELLLQSQRPE-------VEEMIRDM 187
+ L Q +T++ QEE R+ + +K++ +E+ LQ Q E +E I +
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369
Query: 188 GVG-----------QSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
+ S VE L +KE ENL + + DKL K ++++L
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRL 1425
Query: 237 QTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESP 296
Q ELD ++L + ++ + + +K+ +K +L E N+ ++ DR E+
Sbjct: 1426 Q---QELDDLVVDLDNQRQLVSNLEKK---QRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
Query: 297 APVEVNLKLRR 307
L L R
Sbjct: 1480 EKETKALSLAR 1490
Score = 38.9 bits (89), Expect = 0.010
Identities = 51/215 (23%), Positives = 97/215 (45%), Gaps = 18/215 (8%)
Query: 90 LSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMK-YLEQQQDE 148
L K++ +R ++++ + D + ++ ++ + L K++ T ++MK LE+ +DE
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE-LEKSKRALETQMEEMKTQLEELEDE 1554
Query: 149 TKQAQEEARRLRSKMKTME-QIELLLQSQRPEVEEMIRDMGVGQSAVE--------QLAV 199
+ ++ RL M+ ++ Q E LQ++ + EE R + E Q A+
Sbjct: 1555 LQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1614
Query: 200 YCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKD--- 256
+ KK +LK+ + + A K R++ KLQ + Q +LE A +D
Sbjct: 1615 AAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDF-QRELEDARASRDEIF 1672
Query: 257 --LQSADKEIMSLKKKLTMLQETLNLPPVASETVD 289
+ +K+ SL+ L LQE L A + D
Sbjct: 1673 ATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD 1707
Score = 36.2 bits (82), Expect = 0.066
Identities = 44/220 (20%), Positives = 90/220 (40%), Gaps = 37/220 (16%)
Query: 75 DAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCST 134
+ E L + D+V + + +K KR + ++ ++ LEE + + + A + E+
Sbjct: 1512 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 135 LKKQMK-----------------------YLEQQQDETKQAQEEARRLRSKMKTMEQIEL 171
LK Q + Y + +DE KQ A + ++ +EL
Sbjct: 1572 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1631
Query: 172 LLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFS 231
S EE A++QL +K L++AR + E+ ++
Sbjct: 1632 QADSAIKGREE----------AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE---- 1677
Query: 232 SRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL 271
+ K +++ ++L Q + +L +A++ + AD E L ++L
Sbjct: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1717
Score = 34.7 bits (78), Expect = 0.19
Identities = 35/187 (18%), Positives = 85/187 (45%), Gaps = 10/187 (5%)
Query: 90 LSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDET 149
L Q +++ + Q D L+ T E + L++ K L + L+ + +
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 150 KQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYE 209
+A+E RL +K + +E+I ++++ E E+ + + Q+ +++A + L+++ E
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL---QAERKKMAQQMLDLEEQLE 960
Query: 210 NLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKK 269
+ AR+ KL+ + ++ +K++ + E+ + K+ + ++ I L
Sbjct: 961 EEEAARQ-------KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013
Query: 270 KLTMLQE 276
L +E
Sbjct: 1014 NLAEEEE 1020
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 55.1 bits (131), Expect = 1e-07
Identities = 58/289 (20%), Positives = 120/289 (41%), Gaps = 42/289 (14%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQK-----------DKEKRDSQVIIDTLRDTLEE 113
DL Q +E++ AE + + D + +L+++ EKR + I L + LEE
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1754
Query: 114 RNATVVSL----QQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTME-- 167
+ ++ ++A +AE L + L + ++ + +Q + + + LRSK+ ME
Sbjct: 1755 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1814
Query: 168 -----------------QIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYEN 210
Q+E ++ + E + + + ++++ + +K E
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874
Query: 211 LKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
KE + +L++ L + + Q + + + + EL A + ++ +E+ +LK K
Sbjct: 1875 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934
Query: 271 LTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRRPSFRDDIDLNAT 319
L ET +P + + R V+E+ E R D D N T
Sbjct: 1935 LRRGNETSFVP--SRRSGGRRVIENADGSEEETDTR------DADFNGT 1975
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/250 (22%), Positives = 111/250 (44%), Gaps = 32/250 (12%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L+ +LD+ RA ++ +K+KRD ++ L+ LE+ + + Q+ K E + LKK
Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA 1189
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLA 198
+ +ET+ + + + +R Q VEE+ + + A L
Sbjct: 1190 L------DEETRSHEAQVQEMR-------------QKHAQAVEELTEQLEQFKRAKANLD 1230
Query: 199 VYCVSLKKEYENLKEARKASGEVADKL---RKDLFSSRSKLQTVYSELDQAKLELKSAQK 255
+L+KE +L + G+ ++ +K L + +LQ+ S+ ++A+ EL
Sbjct: 1231 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1290
Query: 256 DLQSADKEIMSL-----KKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLR---- 306
LQ+ + + + K + + ++ +L +T + L E+ + V+ KLR
Sbjct: 1291 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1350
Query: 307 -RPSFRDDID 315
R S +D +D
Sbjct: 1351 ERNSLQDQLD 1360
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/297 (19%), Positives = 133/297 (44%), Gaps = 15/297 (5%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L+ E ++++ QL ++ + K++ + I TL L + + + E +K+
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKT-MEQIELLLQSQRPEVEEMIRDMGVGQSAVEQL 197
++ L QQ +E A ++ + +++++ ++ + + L +QR +++ ++ Q +QL
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR----QLVSNLEKKQRKFDQL 1463
Query: 198 AVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYS--ELDQAKLELKSAQK 255
++ +Y + E +A E +K K L +R+ + + + EL++ LK+ +
Sbjct: 1464 LAEEKNISSKYAD--ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521
Query: 256 DLQSA----DKEIMSLKKKLTMLQETL-NLPPVASETVDRLVLESPAPVEVNLKLRRPSF 310
DL S+ K + L+K L+ + + E D L A + + + ++
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1581
Query: 311 RDDIDLNATFDVDTPPARPSSSQ-HGYYEKLCLEKSHSPIQDVPKKICKGPRKESQL 366
+ + DL A + + R Q H Y +L E+ + KK +G K+ +L
Sbjct: 1582 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1638
Score = 44.3 bits (103), Expect = 2e-04
Identities = 54/255 (21%), Positives = 117/255 (45%), Gaps = 13/255 (5%)
Query: 59 INKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLE----ER 114
I+ L +LA+EEE + LKN+ +++ ++L + K++ S+ ++ L+ LE +
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1074
Query: 115 NATVVSLQQALGKAEMLCSTLKKQMK-YLEQQQDETKQAQEEARRLRSKMKTMEQIELLL 173
+ + LQ + + +M + +++++ L + DE Q +++R + ++ L
Sbjct: 1075 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1134
Query: 174 QSQRP---EVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADK-LRKDL 229
S+R + E+ RD+G A++ + + L+ R+ V K L ++
Sbjct: 1135 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1194
Query: 230 FSSRSKLQTVYSELDQAKLELKSAQKDLQSA----DKEIMSLKKKLTMLQETLNLPPVAS 285
S +++Q + + QA EL + + A DK +L+K+ L L + A
Sbjct: 1195 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1254
Query: 286 ETVDRLVLESPAPVE 300
+ V+ + A V+
Sbjct: 1255 QEVEHKKKKLEAQVQ 1269
Score = 43.1 bits (100), Expect = 5e-04
Identities = 28/147 (19%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Query: 137 KQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQ 196
+Q + ++ ++DE ++ +E ++ +++K +EQ L ++ ++E ++ + E+
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915
Query: 197 LAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKD 256
+ V + K+E E + +A E + + L + R K+ +L++ E ++A++
Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975
Query: 257 LQ----SADKEIMSLKKKLTMLQETLN 279
LQ +A+ +I L+ ++ ++ + N
Sbjct: 976 LQLEKVTAEAKIKKLEDEILVMDDQNN 1002
Score = 40.4 bits (93), Expect = 0.003
Identities = 57/251 (22%), Positives = 106/251 (42%), Gaps = 32/251 (12%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
++++ + AQ+ + + D + L D + + V S+ L +AE L K
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 139 MKYLEQQQDETKQA-QEEARR---LRSKMKTMEQIELLLQSQRPE-------VEEMIRDM 187
+ L Q +T++ QEE R+ + +K++ +E+ LQ Q E +E I +
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1376
Query: 188 GVG-----------QSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
+ S VE L +KE ENL + + DKL K ++++L
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRL 1432
Query: 237 QTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESP 296
Q ELD ++L + ++ + + +K+ +K +L E N+ ++ DR E+
Sbjct: 1433 Q---QELDDLVVDLDNQRQLVSNLEKK---QRKFDQLLAEEKNISSKYADERDRAEAEAR 1486
Query: 297 APVEVNLKLRR 307
L L R
Sbjct: 1487 EKETKALSLAR 1497
Score = 38.9 bits (89), Expect = 0.010
Identities = 51/215 (23%), Positives = 97/215 (45%), Gaps = 18/215 (8%)
Query: 90 LSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMK-YLEQQQDE 148
L K++ +R ++++ + D + ++ ++ + L K++ T ++MK LE+ +DE
Sbjct: 1503 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE-LEKSKRALETQMEEMKTQLEELEDE 1561
Query: 149 TKQAQEEARRLRSKMKTME-QIELLLQSQRPEVEEMIRDMGVGQSAVE--------QLAV 199
+ ++ RL M+ ++ Q E LQ++ + EE R + E Q A+
Sbjct: 1562 LQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1621
Query: 200 YCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKD--- 256
+ KK +LK+ + + A K R++ KLQ + Q +LE A +D
Sbjct: 1622 AAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDF-QRELEDARASRDEIF 1679
Query: 257 --LQSADKEIMSLKKKLTMLQETLNLPPVASETVD 289
+ +K+ SL+ L LQE L A + D
Sbjct: 1680 ATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD 1714
Score = 36.2 bits (82), Expect = 0.066
Identities = 44/220 (20%), Positives = 90/220 (40%), Gaps = 37/220 (16%)
Query: 75 DAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCST 134
+ E L + D+V + + +K KR + ++ ++ LEE + + + A + E+
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1578
Query: 135 LKKQMK-----------------------YLEQQQDETKQAQEEARRLRSKMKTMEQIEL 171
LK Q + Y + +DE KQ A + ++ +EL
Sbjct: 1579 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1638
Query: 172 LLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFS 231
S EE A++QL +K L++AR + E+ ++
Sbjct: 1639 QADSAIKGREE----------AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE---- 1684
Query: 232 SRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL 271
+ K +++ ++L Q + +L +A++ + AD E L ++L
Sbjct: 1685 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1724
Score = 34.7 bits (78), Expect = 0.19
Identities = 35/187 (18%), Positives = 85/187 (45%), Gaps = 10/187 (5%)
Query: 90 LSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDET 149
L Q +++ + Q D L+ T E + L++ K L + L+ + +
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 150 KQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYE 209
+A+E RL +K + +E+I ++++ E E+ + + Q+ +++A + L+++ E
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL---QAERKKMAQQMLDLEEQLE 967
Query: 210 NLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKK 269
+ AR+ KL+ + ++ +K++ + E+ + K+ + ++ I L
Sbjct: 968 EEEAARQ-------KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020
Query: 270 KLTMLQE 276
L +E
Sbjct: 1021 NLAEEEE 1027
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 55.1 bits (131), Expect = 1e-07
Identities = 60/231 (25%), Positives = 99/231 (42%), Gaps = 9/231 (3%)
Query: 77 EFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLK 136
E LK + D V +Q + ++ V + +++ E N + + E L TL
Sbjct: 1446 EELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLS 1505
Query: 137 KQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVG-QSAVE 195
++ Q++T Q Q E RLR ++ E L+ Q E EE R V +S +
Sbjct: 1506 EKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIA 1565
Query: 196 QLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQ- 254
LA L KE E LK+ A + D+L + + +S+ + S L++ EL+ Q
Sbjct: 1566 HLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLER---ELREHQE 1622
Query: 255 KDLQSADK-EIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLK 304
+ L+ D+ + S K Q TL P + E R + + P N+K
Sbjct: 1623 RHLEQRDEPQEPSNKVPEQQRQITLKTTPASGE---RGIASTSDPPTANIK 1670
Score = 45.1 bits (105), Expect = 1e-04
Identities = 45/215 (20%), Positives = 106/215 (49%), Gaps = 14/215 (6%)
Query: 67 AQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQV-IIDTLRDTLEERNATVVSLQQAL 125
+Q E+ + LK +L+N ++ Q+ R+ V ++DT R E N + + ++ L
Sbjct: 839 SQIEKLEHEISHLKKKLEN---EVEQRHTLTRNLDVQLLDTKRQLDTETNLHL-NTKELL 894
Query: 126 GKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIR 185
A+ +TLK+ + +E Q ++ +Q + S + ++ + L+ +V ++
Sbjct: 895 KNAQKEIATLKQHLSNMEVQV-ASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKE 953
Query: 186 DMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQ 245
+ S VEQ SL++ K+ V +++RK++ + ++L++
Sbjct: 954 RLKTSTSNVEQYQAMVTSLEESLNKEKQ-------VTEEVRKNIEVRLKESAEFQTQLEK 1006
Query: 246 AKLELKSAQKDLQSADKE-IMSLKKKLTMLQETLN 279
+E++ +++LQ + I S++++L+ L++TL+
Sbjct: 1007 KLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLS 1041
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/201 (20%), Positives = 86/201 (42%), Gaps = 6/201 (2%)
Query: 68 QEEENVLDAEFLKNELD-NVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALG 126
QE ++ L+AE K ++ AQ + K+ V+++T + EE+ LQQ
Sbjct: 1236 QELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQA 1295
Query: 127 KAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTME--QIELLLQSQRPEVEE-- 182
K L + + + +++ Q E + L +K + L+ Q + P+ EE
Sbjct: 1296 KVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYR 1355
Query: 183 -MIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYS 241
++ + V ++QL LK E + + + L++DL R++ +T+
Sbjct: 1356 KLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQK 1415
Query: 242 ELDQAKLELKSAQKDLQSADK 262
+LD ++++ K + K
Sbjct: 1416 DLDAKIIDIQEKVKTITQVKK 1436
Score = 41.6 bits (96), Expect = 0.002
Identities = 59/259 (22%), Positives = 112/259 (43%), Gaps = 43/259 (16%)
Query: 43 SRTCPQCRIQVGKRTIINKLF------FDLAQEEENVLDAEFL--KNELDNVRAQLSQKD 94
+R C R+++ K K ++AQ+ + ++F K EL+ + L + +
Sbjct: 72 TRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTN 131
Query: 95 KEKRDSQVI------IDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQD- 147
+ R SQ + + L + L+E N T LQ L + + ++K + K LEQ+++
Sbjct: 132 E--RLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKEL 189
Query: 148 ----------ETKQAQEEARRL-RSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQ 196
E K +E L R K + +++ L++++ EV + M +++ E
Sbjct: 190 LHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEH 249
Query: 197 LAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVY-----------SELDQ 245
L + L LKEA++ + +K +L ++ KL +Y +EL +
Sbjct: 250 LQKHVEDL---LTKLKEAKEQQASMEEKFHNEL-NAHIKLSNLYKSAADDSEAKSNELTR 305
Query: 246 AKLELKSAQKDLQSADKEI 264
A EL K+ A+K I
Sbjct: 306 AVEELHKLLKEAGEANKAI 324
Score = 41.6 bits (96), Expect = 0.002
Identities = 40/213 (18%), Positives = 91/213 (42%), Gaps = 26/213 (12%)
Query: 80 KNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQM 139
K ++D++ +QL Q +++ D + + T +E+ A V SL+++L K + + ++K +
Sbjct: 931 KEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNI 990
Query: 140 ---------------KYLEQQQDETKQAQEEARRLRSKM--------KTMEQIELLLQSQ 176
K L + + E ++ Q++ RR M KT+ ++ +Q
Sbjct: 991 EVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEA 1050
Query: 177 RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYEN---LKEARKASGEVADKLRKDLFSSR 233
+ + + ++ A V + +YE L A + + A + + S R
Sbjct: 1051 LQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVR 1110
Query: 234 SKLQTVYSELDQAKLELKSAQKDLQSADKEIMS 266
L+ + + LE K++ ++ + K+ +S
Sbjct: 1111 QHLEETTQKAESQLLECKASWEERERMLKDEVS 1143
Score = 38.9 bits (89), Expect = 0.010
Identities = 50/224 (22%), Positives = 101/224 (45%), Gaps = 21/224 (9%)
Query: 52 QVGKRTIINKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTL 111
QV +RT +NKL + +N L+ +FL ++ + + +K K +S+ + L
Sbjct: 7 QVLERTELNKL----PKSVQNKLE-KFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRL 61
Query: 112 EERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM-KTMEQIE 170
+V+ + + L Q+K L ++ E + AQ+ ++S+ +T E++E
Sbjct: 62 SHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELE 121
Query: 171 LLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLF 230
E ++IR + ++L +K+ E LKE+ GE+ KL +L
Sbjct: 122 -------AEKRDLIR---TNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKL-DELQ 170
Query: 231 SSRSKLQTVYSELDQAKLELKS----AQKDLQSADKEIMSLKKK 270
+S ++ L+Q K L S +L++ E+++L ++
Sbjct: 171 ASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGRE 214
Score = 38.5 bits (88), Expect = 0.013
Identities = 57/258 (22%), Positives = 119/258 (46%), Gaps = 32/258 (12%)
Query: 58 IINKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEK-RDSQVIIDTLRDTL--EER 114
IIN + DL E + AE VRA+ +K+KE + S+V + R++L E+R
Sbjct: 759 IINTMTQDLRGANEKLAVAE--------VRAENLKKEKEMLKLSEVRLSQQRESLLAEQR 810
Query: 115 --NATVVSLQQALGKAEMLCSTLKK----QMKYLEQQQDETKQAQEEARRLRSKMKTMEQ 168
N + +LQ G E + K+ Q++ LE + K+ E R +
Sbjct: 811 GQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLD 870
Query: 169 IELLLQSQRPEVEEMIR--DMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLR 226
++LL ++ + E + + ++A +++A +LK+ N++ + + + + +
Sbjct: 871 VQLLDTKRQLDTETNLHLNTKELLKNAQKEIA----TLKQHLSNMEV--QVASQSSQRTG 924
Query: 227 KDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASE 286
K S++ + + S+L Q + ++ ++ L+++ + + +T L+E+LN +E
Sbjct: 925 KGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTE 984
Query: 287 TVDRLVLESPAPVEVNLK 304
V + +EV LK
Sbjct: 985 EVRK-------NIEVRLK 995
Score = 35.4 bits (80), Expect = 0.11
Identities = 40/188 (21%), Positives = 77/188 (40%), Gaps = 19/188 (10%)
Query: 108 RDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM---- 163
R+ E ++ + LQ L A L+K ++ Q D + ++ R L S+
Sbjct: 566 REEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVA 625
Query: 164 -----KTMEQIELLLQSQRPEVEEMIRDMGV-----GQSAVEQLAVYCVSLKKEYENLK- 212
+++ + L +RP + + A+E A L++ +EN K
Sbjct: 626 IPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAAL-KQLQEIFENYKK 684
Query: 213 ---EARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKK 269
E K E +KL++ + RS+ + ++LD A + Q +++ +EI SL +
Sbjct: 685 EKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHE 744
Query: 270 KLTMLQET 277
+ L T
Sbjct: 745 RNQKLTAT 752
Score = 34.3 bits (77), Expect = 0.25
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 27/204 (13%)
Query: 121 LQQALGKAEMLC---STLKKQMKYLEQQQDETK--QAQEEARRLRSKMKTMEQIELLLQS 175
LQQ L + E+ S K K+L QQ E + + E ++ S+ + E + L S
Sbjct: 5 LQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHS 64
Query: 176 QRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSK 235
Q V E C SL+ E E L KA E K+L ++ +
Sbjct: 65 QERLVNETRE---------------CQSLRLELEKLNNQLKALTEK----NKELEIAQDR 105
Query: 236 LQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVD---RLV 292
+ S+ + K EL++ ++DL ++ + + LT + LN S T +L
Sbjct: 106 NIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLK 165
Query: 293 LESPAPVEVNLKLRRPSFRDDIDL 316
L+ +V++K R + +L
Sbjct: 166 LDELQASDVSVKYREKRLEQEKEL 189
Score = 33.9 bits (76), Expect = 0.33
Identities = 37/194 (19%), Positives = 85/194 (43%), Gaps = 24/194 (12%)
Query: 82 ELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVS-LQQALGKAEMLCSTLKKQMK 140
EL + + + +K +D + ++ +D +E+ + L++ L A L S K++
Sbjct: 309 ELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGA 368
Query: 141 YLEQQQ--DETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQ---SAVE 195
L +++ + A A+ ++ MK E +++Q + E + + + + V+
Sbjct: 369 ILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVK 428
Query: 196 QLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQK 255
++ LK++ E + A+KA ++ KL +QA E++ Q+
Sbjct: 429 EVEAKAPILKRQREEYERAQKAVASLSVKL------------------EQAMKEIQRLQE 470
Query: 256 DLQSADKEIMSLKK 269
D A+K+ L++
Sbjct: 471 DTDKANKQSSVLER 484
Score = 33.9 bits (76), Expect = 0.33
Identities = 36/207 (17%), Positives = 95/207 (45%), Gaps = 18/207 (8%)
Query: 70 EENVLDAEFLKNELDN-VRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGK- 127
++++L+ E K++++ + ++ + +KE ++ ++ + R ++S ++
Sbjct: 325 QDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATK-----RKGAILSEEELAAMS 379
Query: 128 --AEMLCSTLKKQMKYLE------QQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPE 179
A + +K MK E + QD+ + E +R+ K +++I ++++ P
Sbjct: 380 PTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRIN---KYLDEIVKEVEAKAPI 436
Query: 180 VEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTV 239
++ + Q AV L+V KE + L+E + + + L +D +++ +
Sbjct: 437 LKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDL 496
Query: 240 YSELDQAKLELKSAQKDLQSADKEIMS 266
++ +EL+ A+ + D+E+ S
Sbjct: 497 SQQIRVLLMELEEARGNHVIRDEEVSS 523
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 55.1 bits (131), Expect = 1e-07
Identities = 64/247 (25%), Positives = 105/247 (42%), Gaps = 21/247 (8%)
Query: 68 QEEENVLDAEFLKNELDNVRAQ----LSQKDKEKRDSQVIIDTLRDTLEER-----NATV 118
Q+ E EF K+EL A+ L + K ++ + +++ R+ LE+ N+ V
Sbjct: 856 QQREEKSQWEFEKDELTQECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMV 915
Query: 119 VSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRP 178
V QQ L E L + + Q L Q E K + + R R ++ L SQR
Sbjct: 916 VERQQLLQDLEDLRNVSETQQSLLSDQILELKSSHKRELREREEVLCQAGASEQLASQRL 975
Query: 179 EVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQT 238
E EM D + + LA+ EN+ KA+ E AD+ R ++ + S+LQ+
Sbjct: 976 ERLEMEHDQERQEMMSKLLAM---------ENI---HKATCETADRERAEMSTEISRLQS 1023
Query: 239 VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAP 298
E+ QA L Q Q +E + L++LQ+ L + + L
Sbjct: 1024 KIKEMQQATSPLSMLQSGCQVIGEEEVEGDGALSLLQQGEQLLEENGDVLLSLQRAHEQA 1083
Query: 299 VEVNLKL 305
V+ N+K+
Sbjct: 1084 VKENVKM 1090
Score = 48.5 bits (114), Expect = 1e-05
Identities = 50/230 (21%), Positives = 103/230 (44%), Gaps = 38/230 (16%)
Query: 70 EENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAE 129
++N + E L+ + L QK+KE +S LEER +L++ L + +
Sbjct: 1604 QKNSQNQEKLQELNQRLTEMLCQKEKEPGNS---------ALEEREQEKFNLKEELERCK 1654
Query: 130 MLCSTLKKQMKY-LEQQQDETKQAQEEARRLRSKMKTMEQI------------------- 169
+ STL ++ L + + +T Q+E L+ +++ M+Q+
Sbjct: 1655 VQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSY 1714
Query: 170 -ELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD 228
E LL+ + EE+ S V++LA + L+ +K+ +K+ + L+
Sbjct: 1715 NEKLLKEKEALSEEL-------NSCVDKLAKSSL-LEHRIATMKQEQKSWEHQSASLKSQ 1766
Query: 229 LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
L +S+ K+Q + + L++ + DL+ +E +LK+++ L + L
Sbjct: 1767 LVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSLHKQL 1816
Score = 33.9 bits (76), Expect = 0.33
Identities = 43/206 (20%), Positives = 95/206 (46%), Gaps = 32/206 (15%)
Query: 91 SQKDKEKRDSQVIIDT------LRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQ 144
+ +++ + +QVI++ +D + AT+ L+ K + L LK+++ L +
Sbjct: 1424 THQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTILVK 1483
Query: 145 QQDETKQAQEEARRLRSKM--------KTMEQIELL------LQSQ----RPEVEEMIRD 186
Q+D ++E L++ M + +++ELL LQ + R E+ + +
Sbjct: 1484 QKDVLSHGEKE-EELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEE 1542
Query: 187 MGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQA 246
+ + L + ++ E +K+ A ++ + L+K + S+L+ +LD
Sbjct: 1543 DSISNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQI----SELKIKNQQLDLE 1598
Query: 247 KLELKSAQKDLQSADKEIMSLKKKLT 272
EL +QK+ Q+ +K + L ++LT
Sbjct: 1599 NTEL--SQKNSQNQEK-LQELNQRLT 1621
Score = 30.8 bits (68), Expect = 2.8
Identities = 40/192 (20%), Positives = 77/192 (40%), Gaps = 25/192 (13%)
Query: 111 LEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM-----KT 165
LEE ++SLQ+A +A + ++ L+Q+ + + + L T
Sbjct: 1066 LEENGDVLLSLQRAHEQAVKENVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNT 1125
Query: 166 MEQIELLLQSQRPEV--------------EEMIRDMG-VGQSAVEQLAVYCVSLKKEYEN 210
EQ E LQ R + ++ +RD+G G S+V++ V + E
Sbjct: 1126 AEQTEPFLQQNRTKQVEGVTRRHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEG 1185
Query: 211 LKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
E E +++ R + + ++++ + +L + A + Q ++ LKKK
Sbjct: 1186 FSEL-----ENSEETRTESWELKNQISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKK 1240
Query: 271 LTMLQETLNLPP 282
L ML+ P
Sbjct: 1241 LKMLERIPEASP 1252
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 55.1 bits (131), Expect = 1e-07
Identities = 64/247 (25%), Positives = 105/247 (42%), Gaps = 21/247 (8%)
Query: 68 QEEENVLDAEFLKNELDNVRAQ----LSQKDKEKRDSQVIIDTLRDTLEER-----NATV 118
Q+ E EF K+EL A+ L + K ++ + +++ R+ LE+ N+ V
Sbjct: 850 QQREEKSQWEFEKDELTQECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMV 909
Query: 119 VSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRP 178
V QQ L E L + + Q L Q E K + + R R ++ L SQR
Sbjct: 910 VERQQLLQDLEDLRNVSETQQSLLSDQILELKSSHKRELREREEVLCQAGASEQLASQRL 969
Query: 179 EVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQT 238
E EM D + + LA+ EN+ KA+ E AD+ R ++ + S+LQ+
Sbjct: 970 ERLEMEHDQERQEMMSKLLAM---------ENI---HKATCETADRERAEMSTEISRLQS 1017
Query: 239 VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAP 298
E+ QA L Q Q +E + L++LQ+ L + + L
Sbjct: 1018 KIKEMQQATSPLSMLQSGCQVIGEEEVEGDGALSLLQQGEQLLEENGDVLLSLQRAHEQA 1077
Query: 299 VEVNLKL 305
V+ N+K+
Sbjct: 1078 VKENVKM 1084
Score = 48.5 bits (114), Expect = 1e-05
Identities = 50/230 (21%), Positives = 103/230 (44%), Gaps = 38/230 (16%)
Query: 70 EENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAE 129
++N + E L+ + L QK+KE +S LEER +L++ L + +
Sbjct: 1598 QKNSQNQEKLQELNQRLTEMLCQKEKEPGNS---------ALEEREQEKFNLKEELERCK 1648
Query: 130 MLCSTLKKQMKY-LEQQQDETKQAQEEARRLRSKMKTMEQI------------------- 169
+ STL ++ L + + +T Q+E L+ +++ M+Q+
Sbjct: 1649 VQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSY 1708
Query: 170 -ELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD 228
E LL+ + EE+ S V++LA + L+ +K+ +K+ + L+
Sbjct: 1709 NEKLLKEKEALSEEL-------NSCVDKLAKSSL-LEHRIATMKQEQKSWEHQSASLKSQ 1760
Query: 229 LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
L +S+ K+Q + + L++ + DL+ +E +LK+++ L + L
Sbjct: 1761 LVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSLHKQL 1810
Score = 33.9 bits (76), Expect = 0.33
Identities = 43/206 (20%), Positives = 95/206 (46%), Gaps = 32/206 (15%)
Query: 91 SQKDKEKRDSQVIIDT------LRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQ 144
+ +++ + +QVI++ +D + AT+ L+ K + L LK+++ L +
Sbjct: 1418 THQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTILVK 1477
Query: 145 QQDETKQAQEEARRLRSKM--------KTMEQIELL------LQSQ----RPEVEEMIRD 186
Q+D ++E L++ M + +++ELL LQ + R E+ + +
Sbjct: 1478 QKDVLSHGEKE-EELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEE 1536
Query: 187 MGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQA 246
+ + L + ++ E +K+ A ++ + L+K + S+L+ +LD
Sbjct: 1537 DSISNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQI----SELKIKNQQLDLE 1592
Query: 247 KLELKSAQKDLQSADKEIMSLKKKLT 272
EL +QK+ Q+ +K + L ++LT
Sbjct: 1593 NTEL--SQKNSQNQEK-LQELNQRLT 1615
Score = 30.8 bits (68), Expect = 2.8
Identities = 40/192 (20%), Positives = 77/192 (40%), Gaps = 25/192 (13%)
Query: 111 LEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM-----KT 165
LEE ++SLQ+A +A + ++ L+Q+ + + + L T
Sbjct: 1060 LEENGDVLLSLQRAHEQAVKENVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNT 1119
Query: 166 MEQIELLLQSQRPEV--------------EEMIRDMG-VGQSAVEQLAVYCVSLKKEYEN 210
EQ E LQ R + ++ +RD+G G S+V++ V + E
Sbjct: 1120 AEQTEPFLQQNRTKQVEGVTRRHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEG 1179
Query: 211 LKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
E E +++ R + + ++++ + +L + A + Q ++ LKKK
Sbjct: 1180 FSEL-----ENSEETRTESWELKNQISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKK 1234
Query: 271 LTMLQETLNLPP 282
L ML+ P
Sbjct: 1235 LKMLERIPEASP 1246
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 55.1 bits (131), Expect = 1e-07
Identities = 64/247 (25%), Positives = 105/247 (42%), Gaps = 21/247 (8%)
Query: 68 QEEENVLDAEFLKNELDNVRAQ----LSQKDKEKRDSQVIIDTLRDTLEER-----NATV 118
Q+ E EF K+EL A+ L + K ++ + +++ R+ LE+ N+ V
Sbjct: 850 QQREEKSQWEFEKDELTQECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMV 909
Query: 119 VSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRP 178
V QQ L E L + + Q L Q E K + + R R ++ L SQR
Sbjct: 910 VERQQLLQDLEDLRNVSETQQSLLSDQILELKSSHKRELREREEVLCQAGASEQLASQRL 969
Query: 179 EVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQT 238
E EM D + + LA+ EN+ KA+ E AD+ R ++ + S+LQ+
Sbjct: 970 ERLEMEHDQERQEMMSKLLAM---------ENI---HKATCETADRERAEMSTEISRLQS 1017
Query: 239 VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAP 298
E+ QA L Q Q +E + L++LQ+ L + + L
Sbjct: 1018 KIKEMQQATSPLSMLQSGCQVIGEEEVEGDGALSLLQQGEQLLEENGDVLLSLQRAHEQA 1077
Query: 299 VEVNLKL 305
V+ N+K+
Sbjct: 1078 VKENVKM 1084
Score = 48.5 bits (114), Expect = 1e-05
Identities = 50/230 (21%), Positives = 103/230 (44%), Gaps = 38/230 (16%)
Query: 70 EENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAE 129
++N + E L+ + L QK+KE +S LEER +L++ L + +
Sbjct: 1598 QKNSQNQEKLQELNQRLTEMLCQKEKEPGNS---------ALEEREQEKFNLKEELERCK 1648
Query: 130 MLCSTLKKQMKY-LEQQQDETKQAQEEARRLRSKMKTMEQI------------------- 169
+ STL ++ L + + +T Q+E L+ +++ M+Q+
Sbjct: 1649 VQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSY 1708
Query: 170 -ELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD 228
E LL+ + EE+ S V++LA + L+ +K+ +K+ + L+
Sbjct: 1709 NEKLLKEKEALSEEL-------NSCVDKLAKSSL-LEHRIATMKQEQKSWEHQSASLKSQ 1760
Query: 229 LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
L +S+ K+Q + + L++ + DL+ +E +LK+++ L + L
Sbjct: 1761 LVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSLHKQL 1810
Score = 33.9 bits (76), Expect = 0.33
Identities = 43/206 (20%), Positives = 95/206 (46%), Gaps = 32/206 (15%)
Query: 91 SQKDKEKRDSQVIIDT------LRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQ 144
+ +++ + +QVI++ +D + AT+ L+ K + L LK+++ L +
Sbjct: 1418 THQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTILVK 1477
Query: 145 QQDETKQAQEEARRLRSKM--------KTMEQIELL------LQSQ----RPEVEEMIRD 186
Q+D ++E L++ M + +++ELL LQ + R E+ + +
Sbjct: 1478 QKDVLSHGEKE-EELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEE 1536
Query: 187 MGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQA 246
+ + L + ++ E +K+ A ++ + L+K + S+L+ +LD
Sbjct: 1537 DSISNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQI----SELKIKNQQLDLE 1592
Query: 247 KLELKSAQKDLQSADKEIMSLKKKLT 272
EL +QK+ Q+ +K + L ++LT
Sbjct: 1593 NTEL--SQKNSQNQEK-LQELNQRLT 1615
Score = 30.8 bits (68), Expect = 2.8
Identities = 40/192 (20%), Positives = 77/192 (40%), Gaps = 25/192 (13%)
Query: 111 LEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM-----KT 165
LEE ++SLQ+A +A + ++ L+Q+ + + + L T
Sbjct: 1060 LEENGDVLLSLQRAHEQAVKENVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNT 1119
Query: 166 MEQIELLLQSQRPEV--------------EEMIRDMG-VGQSAVEQLAVYCVSLKKEYEN 210
EQ E LQ R + ++ +RD+G G S+V++ V + E
Sbjct: 1120 AEQTEPFLQQNRTKQVEGVTRRHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEG 1179
Query: 211 LKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
E E +++ R + + ++++ + +L + A + Q ++ LKKK
Sbjct: 1180 FSEL-----ENSEETRTESWELKNQISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKK 1234
Query: 271 LTMLQETLNLPP 282
L ML+ P
Sbjct: 1235 LKMLERIPEASP 1246
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 55.1 bits (131), Expect = 1e-07
Identities = 64/247 (25%), Positives = 105/247 (42%), Gaps = 21/247 (8%)
Query: 68 QEEENVLDAEFLKNELDNVRAQ----LSQKDKEKRDSQVIIDTLRDTLEER-----NATV 118
Q+ E EF K+EL A+ L + K ++ + +++ R+ LE+ N+ V
Sbjct: 850 QQREEKSQWEFEKDELTQECAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMV 909
Query: 119 VSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRP 178
V QQ L E L + + Q L Q E K + + R R ++ L SQR
Sbjct: 910 VERQQLLQDLEDLRNVSETQQSLLSDQILELKSSHKRELREREEVLCQAGASEQLASQRL 969
Query: 179 EVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQT 238
E EM D + + LA+ EN+ KA+ E AD+ R ++ + S+LQ+
Sbjct: 970 ERLEMEHDQERQEMMSKLLAM---------ENI---HKATCETADRERAEMSTEISRLQS 1017
Query: 239 VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAP 298
E+ QA L Q Q +E + L++LQ+ L + + L
Sbjct: 1018 KIKEMQQATSPLSMLQSGCQVIGEEEVEGDGALSLLQQGEQLLEENGDVLLSLQRAHEQA 1077
Query: 299 VEVNLKL 305
V+ N+K+
Sbjct: 1078 VKENVKM 1084
Score = 48.5 bits (114), Expect = 1e-05
Identities = 50/230 (21%), Positives = 103/230 (44%), Gaps = 38/230 (16%)
Query: 70 EENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAE 129
++N + E L+ + L QK+KE +S LEER +L++ L + +
Sbjct: 1598 QKNSQNQEKLQELNQRLTEMLCQKEKEPGNS---------ALEEREQEKFNLKEELERCK 1648
Query: 130 MLCSTLKKQMKY-LEQQQDETKQAQEEARRLRSKMKTMEQI------------------- 169
+ STL ++ L + + +T Q+E L+ +++ M+Q+
Sbjct: 1649 VQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSY 1708
Query: 170 -ELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD 228
E LL+ + EE+ S V++LA + L+ +K+ +K+ + L+
Sbjct: 1709 NEKLLKEKEALSEEL-------NSCVDKLAKSSL-LEHRIATMKQEQKSWEHQSASLKSQ 1760
Query: 229 LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
L +S+ K+Q + + L++ + DL+ +E +LK+++ L + L
Sbjct: 1761 LVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVMSLHKQL 1810
Score = 33.9 bits (76), Expect = 0.33
Identities = 43/206 (20%), Positives = 95/206 (46%), Gaps = 32/206 (15%)
Query: 91 SQKDKEKRDSQVIIDT------LRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQ 144
+ +++ + +QVI++ +D + AT+ L+ K + L LK+++ L +
Sbjct: 1418 THQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQELTRKLKERVTILVK 1477
Query: 145 QQDETKQAQEEARRLRSKM--------KTMEQIELL------LQSQ----RPEVEEMIRD 186
Q+D ++E L++ M + +++ELL LQ + R E+ + +
Sbjct: 1478 QKDVLSHGEKE-EELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEE 1536
Query: 187 MGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQA 246
+ + L + ++ E +K+ A ++ + L+K + S+L+ +LD
Sbjct: 1537 DSISNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQI----SELKIKNQQLDLE 1592
Query: 247 KLELKSAQKDLQSADKEIMSLKKKLT 272
EL +QK+ Q+ +K + L ++LT
Sbjct: 1593 NTEL--SQKNSQNQEK-LQELNQRLT 1615
Score = 30.8 bits (68), Expect = 2.8
Identities = 40/192 (20%), Positives = 77/192 (40%), Gaps = 25/192 (13%)
Query: 111 LEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM-----KT 165
LEE ++SLQ+A +A + ++ L+Q+ + + + L T
Sbjct: 1060 LEENGDVLLSLQRAHEQAVKENVKMATEISRLQQRLQKLEPGLVMSSCLDEPATEFFGNT 1119
Query: 166 MEQIELLLQSQRPEV--------------EEMIRDMG-VGQSAVEQLAVYCVSLKKEYEN 210
EQ E LQ R + ++ +RD+G G S+V++ V + E
Sbjct: 1120 AEQTEPFLQQNRTKQVEGVTRRHVLSDLEDDEVRDLGSTGTSSVQRQEVKIEESEASVEG 1179
Query: 211 LKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
E E +++ R + + ++++ + +L + A + Q ++ LKKK
Sbjct: 1180 FSEL-----ENSEETRTESWELKNQISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKK 1234
Query: 271 LTMLQETLNLPP 282
L ML+ P
Sbjct: 1235 LKMLERIPEASP 1246
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 54.7 bits (130), Expect = 2e-07
Identities = 53/235 (22%), Positives = 106/235 (45%), Gaps = 37/235 (15%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAE----MLCST 134
L+ +L++ RA ++ +K+KRD ++ L+ LE+ + + Q+ K E +L T
Sbjct: 1116 LQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKT 1175
Query: 135 LKKQMKYLEQQQDETKQAQ-----------EEARRLRSKMKTMEQ------------IEL 171
L+++ K E Q E +Q E+ +R+++ ++ +Q +++
Sbjct: 1176 LEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
Query: 172 LLQS------QRPEVEEMIRDMGV----GQSAVEQLAVYCVSLKKEYENLKEARKASGEV 221
LLQ +R +VE ++++ V G+ +LA L+ E +N+ S
Sbjct: 1236 LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSK 1295
Query: 222 ADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
+ KL KD + S+LQ L + + S L+ + E S +++L +E
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE 1350
Score = 47.0 bits (110), Expect = 4e-05
Identities = 39/203 (19%), Positives = 100/203 (49%), Gaps = 7/203 (3%)
Query: 75 DAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCST 134
+ E L + D+V + + +K KR + ++ ++ LEE + + + A + E+
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQA 1564
Query: 135 LKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAV 194
+K Q + Q +DE Q++E+ ++L ++ + ++E L+ +R + + + +
Sbjct: 1565 MKAQFERDLQGRDE--QSEEKKKQL---VRQVREMEAELEDERKQRSMAVAARKKLEMDL 1619
Query: 195 EQLAVYCVSLKKEY-ENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSA 253
+ L + S K E +K+ RK ++ D +R +L +R+ + + ++ + + +LKS
Sbjct: 1620 KDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR-ELDDTRASREEILAQAKENEKKLKSM 1678
Query: 254 QKDLQSADKEIMSLKKKLTMLQE 276
+ ++ +E+ + ++ Q+
Sbjct: 1679 EAEMIQLQEELAAAERAKRQAQQ 1701
Score = 45.8 bits (107), Expect = 8e-05
Identities = 68/297 (22%), Positives = 133/297 (44%), Gaps = 61/297 (20%)
Query: 59 INKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKD---KEKRDSQVIIDTLRDTLEERN 115
I +L LA++EE L+ L V + +QK+ K+ R+ + I L++ LE
Sbjct: 1071 IAELKMQLAKKEEE------LQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 116 ATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELL--- 172
A+ KAE L ++++ L+ + ++T + + LRSK + +++ +L
Sbjct: 1125 AS-------RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKRE--QEVNILKKT 1175
Query: 173 LQSQRPEVEEMIRDMGVGQS-AVEQLAVYCVSLKKEYENLKEARKA----SGEVADKL-- 225
L+ + E I++M S AVE+LA K+ NL++A++ GE+A+++
Sbjct: 1176 LEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
Query: 226 -----------RKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQ-----------SADKE 263
RK + + +LQ ++E ++ + EL LQ +D +
Sbjct: 1236 LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSK 1295
Query: 264 IMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLR-----RPSFRDDID 315
L K + L+ L +T + L E+ + ++ KL+ + SFR+ ++
Sbjct: 1296 SSKLTKDFSALESQL------QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE 1346
Score = 43.9 bits (102), Expect = 3e-04
Identities = 53/282 (18%), Positives = 114/282 (40%), Gaps = 26/282 (9%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQKD----KEKRDSQVIIDTLRDTLEERNATVVS 120
+LA E A+ ++EL + A S K +EKR + I L + LEE
Sbjct: 1688 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1747
Query: 121 LQQALGKA----EMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIE------ 170
+ L KA + + + L + + ++ ++ +Q + + + L+ K++ ME
Sbjct: 1748 INDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKA 1807
Query: 171 --LLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD 228
L+++ ++EE + + ++ C +++ + LK+ D R++
Sbjct: 1808 SITALEAKIAQLEEQL------DNETKERQAACKQVRRTEKKLKDVLLQ----VDDERRN 1857
Query: 229 LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETV 288
+ + + L Q K +L+ A+++ Q A+ L+++L ET + ++
Sbjct: 1858 AEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSL 1917
Query: 289 DRLVLESPAPVEVNLKLRRPSFRDDIDLNATFDVDTPPARPS 330
+ P V ++ R D D D A+P+
Sbjct: 1918 KNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAKPA 1959
Score = 43.5 bits (101), Expect = 4e-04
Identities = 48/199 (24%), Positives = 83/199 (41%), Gaps = 26/199 (13%)
Query: 79 LKNELDNVRAQLSQKDKEK----RDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCST 134
L+ ELDNV LSQ D + +D + L+DT E L Q + ++ ST
Sbjct: 1278 LQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQE--------LLQEENRQKLSLST 1329
Query: 135 LKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAV 194
KQ++ + E + +EEA+ +E + + +V +M + M +
Sbjct: 1330 KLKQVEDEKNSFREQLEEEEEAKH---------NLEKQIATLHAQVADMKKKMEDSVGCL 1380
Query: 195 EQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAK-----LE 249
E L+K+ E L + + DKL K + +L + +LD + LE
Sbjct: 1381 ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLE 1440
Query: 250 LKSAQKDLQSADKEIMSLK 268
K + D A+++ +S K
Sbjct: 1441 KKQKKFDQLLAEEKTISAK 1459
Score = 43.5 bits (101), Expect = 4e-04
Identities = 46/224 (20%), Positives = 95/224 (42%), Gaps = 15/224 (6%)
Query: 67 AQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALG 126
A+ E A L L+ Q ++ ++ + + ++ L + ++ +V L+++
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 127 KAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTME-QIELLLQSQRPEVEE--- 182
E +K Q LE+ +DE + ++ RL ++ M+ Q E LQ + + EE
Sbjct: 1529 ALEQQVEEMKTQ---LEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKK 1585
Query: 183 ----MIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQT 238
+R+M + V+ +K+ E + +A + A+K R + KLQ
Sbjct: 1586 QLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQA 1645
Query: 239 ----VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
ELD + + + +K++ S++ ++ LQE L
Sbjct: 1646 QMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEEL 1689
Score = 43.5 bits (101), Expect = 4e-04
Identities = 60/268 (22%), Positives = 119/268 (44%), Gaps = 38/268 (14%)
Query: 50 RIQVGKRTIINKLFFDL-AQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLR 108
R++V + + + DL ++E++ + L ++ + A+L + K++ + L
Sbjct: 1557 RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLE 1616
Query: 109 DTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEE----ARRLRSKMK 164
L++ A + S + +A L+ QMK ++ D+T+ ++EE A+ K+K
Sbjct: 1617 MDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLK 1676
Query: 165 TME------QIELL--------LQSQRPEV-EEMIRDMGVGQSAVEQ---LAVYCVSLKK 206
+ME Q EL Q +R E+ +E+ G G A+E+ L L++
Sbjct: 1677 SMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEE 1736
Query: 207 EYEN-------LKEARKASGEVADKLRKDLFSSRS---KLQTVYSELDQAKLELKSAQKD 256
E E + + K + D++ DL RS K + +L++ ELK ++
Sbjct: 1737 ELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQE 1796
Query: 257 LQSADK-----EIMSLKKKLTMLQETLN 279
++ K I +L+ K+ L+E L+
Sbjct: 1797 MEGTVKSKYKASITALEAKIAQLEEQLD 1824
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/150 (22%), Positives = 74/150 (49%), Gaps = 10/150 (6%)
Query: 134 TLKKQMKYLEQQQDETKQAQEEARRLRSK-------MKTMEQIELLLQSQRPEVEEMIRD 186
T K + + +Q++E +EE ++R K + ME ++ L +++ +++E ++
Sbjct: 832 TKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQA 891
Query: 187 MGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQA 246
+ E+L + K+E E + +A E ++ + L + + K+Q EL++
Sbjct: 892 ETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQ 951
Query: 247 KLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
E +SA++ LQ E ++ + KL L+E
Sbjct: 952 LEEEESARQKLQ---LEKVTTEAKLKKLEE 978
Score = 38.5 bits (88), Expect = 0.013
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 25/223 (11%)
Query: 68 QEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGK 127
QE E + + E + R Q Q +K+K I L + LEE + LQ
Sbjct: 911 QELEEICHDLEARVEEEEERCQHLQAEKKKMQQN--IQELEEQLEEEESARQKLQLEKVT 968
Query: 128 AEMLCSTLKKQMKYLEQQQ----DETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEM 183
E L+++ LE Q E K ++ + + E+ L + + E M
Sbjct: 969 TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAM 1028
Query: 184 IRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVAD------KLRKDLFSSRSKLQ 237
I D+ E K+ E K RK G+ D +L+ + + +L
Sbjct: 1029 ITDLEERLRREE---------KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLA 1079
Query: 238 TVYSELDQ--AKLELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
EL A++E ++AQK++ A K+I L+ +++ LQE L
Sbjct: 1080 KKEEELQAALARVEEEAAQKNM--ALKKIRELESQISELQEDL 1120
Score = 34.7 bits (78), Expect = 0.19
Identities = 40/207 (19%), Positives = 80/207 (38%), Gaps = 13/207 (6%)
Query: 63 FFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQ 122
F + +EEE L+ ++ + AQ++ K+ DS ++T + + + L
Sbjct: 1341 FREQLEEEEEA--KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLS 1398
Query: 123 QALGKAEMLCSTLKKQMKYLEQQQDET----KQAQEEARRLRSKMKTMEQ-------IEL 171
Q + L+K L+Q+ D+ ++ A L K K +Q I
Sbjct: 1399 QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISA 1458
Query: 172 LLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFS 231
+R E R+ ++ + + K E E L + + E + D+
Sbjct: 1459 KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGK 1518
Query: 232 SRSKLQTVYSELDQAKLELKSAQKDLQ 258
S +L+ L+Q E+K+ ++L+
Sbjct: 1519 SVHELEKSKRALEQQVEEMKTQLEELE 1545
Score = 31.6 bits (70), Expect = 1.6
Identities = 36/167 (21%), Positives = 82/167 (49%), Gaps = 20/167 (11%)
Query: 122 QQALGKAEMLCSTLKKQMKYLEQQQD-ETKQAQEEARRLRSKMKTMEQIELL-------- 172
++ + K E L +KQ+ + + ET Q+Q A +L+ + + + EL
Sbjct: 845 EEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRA 904
Query: 173 -LQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFS 231
L +++ E+EE+ D+ ++ VE+ C L+ E + +++ + E+ ++L ++ S
Sbjct: 905 RLTAKKQELEEICHDL---EARVEEEEERCQHLQAEKKKMQQNIQ---ELEEQLEEE-ES 957
Query: 232 SRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
+R KLQ E + +LK +++ + + L K+ +L++ +
Sbjct: 958 ARQKLQL---EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRI 1001
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/250 (22%), Positives = 111/250 (44%), Gaps = 32/250 (12%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L+ +LD+ RA ++ +K+KRD ++ L+ LE+ + + Q+ K E + LKK
Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA 1189
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLA 198
+ +ET+ + + + +R Q VEE+ + + A L
Sbjct: 1190 L------DEETRSHEAQVQEMR-------------QKHAQAVEELTEQLEQFKRAKANLD 1230
Query: 199 VYCVSLKKEYENLKEARKASGEVADKL---RKDLFSSRSKLQTVYSELDQAKLELKSAQK 255
+L+KE +L + G+ ++ +K L + +LQ+ S+ ++A+ EL
Sbjct: 1231 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1290
Query: 256 DLQSADKEIMSL-----KKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLR---- 306
LQ+ + + + K + + ++ +L +T + L E+ + V+ KLR
Sbjct: 1291 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1350
Query: 307 -RPSFRDDID 315
R S +D +D
Sbjct: 1351 ERNSLQDQLD 1360
Score = 51.6 bits (122), Expect = 2e-06
Identities = 46/241 (19%), Positives = 103/241 (42%), Gaps = 34/241 (14%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQK-----------DKEKRDSQVIIDTLRDTLEE 113
DL Q +E++ AE + + D + +L+++ EKR + I L + LEE
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1754
Query: 114 RNATVVSL----QQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTME-- 167
+ ++ ++A +AE L + L + ++ + +Q + + + LRSK+ ME
Sbjct: 1755 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1814
Query: 168 -----------------QIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYEN 210
Q+E ++ + E + + + ++++ + +K E
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874
Query: 211 LKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
KE + +L++ L + + Q + + + + EL A + ++ +E+ +LK K
Sbjct: 1875 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934
Query: 271 L 271
L
Sbjct: 1935 L 1935
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/297 (19%), Positives = 133/297 (44%), Gaps = 15/297 (5%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L+ E ++++ QL ++ + K++ + I TL L + + + E +K+
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKT-MEQIELLLQSQRPEVEEMIRDMGVGQSAVEQL 197
++ L QQ +E A ++ + +++++ ++ + + L +QR +++ ++ Q +QL
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR----QLVSNLEKKQRKFDQL 1463
Query: 198 AVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYS--ELDQAKLELKSAQK 255
++ +Y + E +A E +K K L +R+ + + + EL++ LK+ +
Sbjct: 1464 LAEEKNISSKYAD--ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521
Query: 256 DLQSA----DKEIMSLKKKLTMLQETL-NLPPVASETVDRLVLESPAPVEVNLKLRRPSF 310
DL S+ K + L+K L+ + + E D L A + + + ++
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1581
Query: 311 RDDIDLNATFDVDTPPARPSSSQ-HGYYEKLCLEKSHSPIQDVPKKICKGPRKESQL 366
+ + DL A + + R Q H Y +L E+ + KK +G K+ +L
Sbjct: 1582 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1638
Score = 44.3 bits (103), Expect = 2e-04
Identities = 54/255 (21%), Positives = 117/255 (45%), Gaps = 13/255 (5%)
Query: 59 INKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLE----ER 114
I+ L +LA+EEE + LKN+ +++ ++L + K++ S+ ++ L+ LE +
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1074
Query: 115 NATVVSLQQALGKAEMLCSTLKKQMK-YLEQQQDETKQAQEEARRLRSKMKTMEQIELLL 173
+ + LQ + + +M + +++++ L + DE Q +++R + ++ L
Sbjct: 1075 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1134
Query: 174 QSQRP---EVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADK-LRKDL 229
S+R + E+ RD+G A++ + + L+ R+ V K L ++
Sbjct: 1135 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1194
Query: 230 FSSRSKLQTVYSELDQAKLELKSAQKDLQSA----DKEIMSLKKKLTMLQETLNLPPVAS 285
S +++Q + + QA EL + + A DK +L+K+ L L + A
Sbjct: 1195 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1254
Query: 286 ETVDRLVLESPAPVE 300
+ V+ + A V+
Sbjct: 1255 QEVEHKKKKLEAQVQ 1269
Score = 43.1 bits (100), Expect = 5e-04
Identities = 28/147 (19%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Query: 137 KQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQ 196
+Q + ++ ++DE ++ +E ++ +++K +EQ L ++ ++E ++ + E+
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 915
Query: 197 LAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKD 256
+ V + K+E E + +A E + + L + R K+ +L++ E ++A++
Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975
Query: 257 LQ----SADKEIMSLKKKLTMLQETLN 279
LQ +A+ +I L+ ++ ++ + N
Sbjct: 976 LQLEKVTAEAKIKKLEDEILVMDDQNN 1002
Score = 40.4 bits (93), Expect = 0.003
Identities = 57/251 (22%), Positives = 106/251 (42%), Gaps = 32/251 (12%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
++++ + AQ+ + + D + L D + + V S+ L +AE L K
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 139 MKYLEQQQDETKQA-QEEARR---LRSKMKTMEQIELLLQSQRPE-------VEEMIRDM 187
+ L Q +T++ QEE R+ + +K++ +E+ LQ Q E +E I +
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1376
Query: 188 GVG-----------QSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
+ S VE L +KE ENL + + DKL K ++++L
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRL 1432
Query: 237 QTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESP 296
Q ELD ++L + ++ + + +K+ +K +L E N+ ++ DR E+
Sbjct: 1433 Q---QELDDLVVDLDNQRQLVSNLEKK---QRKFDQLLAEEKNISSKYADERDRAEAEAR 1486
Query: 297 APVEVNLKLRR 307
L L R
Sbjct: 1487 EKETKALSLAR 1497
Score = 38.9 bits (89), Expect = 0.010
Identities = 51/215 (23%), Positives = 97/215 (45%), Gaps = 18/215 (8%)
Query: 90 LSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMK-YLEQQQDE 148
L K++ +R ++++ + D + ++ ++ + L K++ T ++MK LE+ +DE
Sbjct: 1503 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE-LEKSKRALETQMEEMKTQLEELEDE 1561
Query: 149 TKQAQEEARRLRSKMKTME-QIELLLQSQRPEVEEMIRDMGVGQSAVE--------QLAV 199
+ ++ RL M+ ++ Q E LQ++ + EE R + E Q A+
Sbjct: 1562 LQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1621
Query: 200 YCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKD--- 256
+ KK +LK+ + + A K R++ KLQ + Q +LE A +D
Sbjct: 1622 AAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDF-QRELEDARASRDEIF 1679
Query: 257 --LQSADKEIMSLKKKLTMLQETLNLPPVASETVD 289
+ +K+ SL+ L LQE L A + D
Sbjct: 1680 ATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD 1714
Score = 36.2 bits (82), Expect = 0.066
Identities = 44/220 (20%), Positives = 90/220 (40%), Gaps = 37/220 (16%)
Query: 75 DAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCST 134
+ E L + D+V + + +K KR + ++ ++ LEE + + + A + E+
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1578
Query: 135 LKKQMK-----------------------YLEQQQDETKQAQEEARRLRSKMKTMEQIEL 171
LK Q + Y + +DE KQ A + ++ +EL
Sbjct: 1579 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1638
Query: 172 LLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFS 231
S EE A++QL +K L++AR + E+ ++
Sbjct: 1639 QADSAIKGREE----------AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE---- 1684
Query: 232 SRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL 271
+ K +++ ++L Q + +L +A++ + AD E L ++L
Sbjct: 1685 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1724
Score = 34.7 bits (78), Expect = 0.19
Identities = 35/187 (18%), Positives = 85/187 (45%), Gaps = 10/187 (5%)
Query: 90 LSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDET 149
L Q +++ + Q D L+ T E + L++ K L + L+ + +
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 150 KQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYE 209
+A+E RL +K + +E+I ++++ E E+ + + Q+ +++A + L+++ E
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL---QAERKKMAQQMLDLEEQLE 967
Query: 210 NLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKK 269
+ AR+ KL+ + ++ +K++ + E+ + K+ + ++ I L
Sbjct: 968 EEEAARQ-------KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020
Query: 270 KLTMLQE 276
L +E
Sbjct: 1021 NLAEEEE 1027
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/250 (22%), Positives = 111/250 (44%), Gaps = 32/250 (12%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L+ +LD+ RA ++ +K+KRD ++ L+ LE+ + + Q+ K E + LKK
Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA 1182
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLA 198
+ +ET+ + + + +R Q VEE+ + + A L
Sbjct: 1183 L------DEETRSHEAQVQEMR-------------QKHAQAVEELTEQLEQFKRAKANLD 1223
Query: 199 VYCVSLKKEYENLKEARKASGEVADKL---RKDLFSSRSKLQTVYSELDQAKLELKSAQK 255
+L+KE +L + G+ ++ +K L + +LQ+ S+ ++A+ EL
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283
Query: 256 DLQSADKEIMSL-----KKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLR---- 306
LQ+ + + + K + + ++ +L +T + L E+ + V+ KLR
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343
Query: 307 -RPSFRDDID 315
R S +D +D
Sbjct: 1344 ERNSLQDQLD 1353
Score = 51.6 bits (122), Expect = 2e-06
Identities = 46/241 (19%), Positives = 103/241 (42%), Gaps = 34/241 (14%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQK-----------DKEKRDSQVIIDTLRDTLEE 113
DL Q +E++ AE + + D + +L+++ EKR + I L + LEE
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1747
Query: 114 RNATVVSL----QQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTME-- 167
+ ++ ++A +AE L + L + ++ + +Q + + + LRSK+ ME
Sbjct: 1748 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1807
Query: 168 -----------------QIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYEN 210
Q+E ++ + E + + + ++++ + +K E
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867
Query: 211 LKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
KE + +L++ L + + Q + + + + EL A + ++ +E+ +LK K
Sbjct: 1868 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
Query: 271 L 271
L
Sbjct: 1928 L 1928
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/297 (19%), Positives = 133/297 (44%), Gaps = 15/297 (5%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L+ E ++++ QL ++ + K++ + I TL L + + + E +K+
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKT-MEQIELLLQSQRPEVEEMIRDMGVGQSAVEQL 197
++ L QQ +E A ++ + +++++ ++ + + L +QR +++ ++ Q +QL
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR----QLVSNLEKKQRKFDQL 1456
Query: 198 AVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYS--ELDQAKLELKSAQK 255
++ +Y + E +A E +K K L +R+ + + + EL++ LK+ +
Sbjct: 1457 LAEEKNISSKYAD--ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514
Query: 256 DLQSA----DKEIMSLKKKLTMLQETL-NLPPVASETVDRLVLESPAPVEVNLKLRRPSF 310
DL S+ K + L+K L+ + + E D L A + + + ++
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1574
Query: 311 RDDIDLNATFDVDTPPARPSSSQ-HGYYEKLCLEKSHSPIQDVPKKICKGPRKESQL 366
+ + DL A + + R Q H Y +L E+ + KK +G K+ +L
Sbjct: 1575 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1631
Score = 44.3 bits (103), Expect = 2e-04
Identities = 54/255 (21%), Positives = 117/255 (45%), Gaps = 13/255 (5%)
Query: 59 INKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLE----ER 114
I+ L +LA+EEE + LKN+ +++ ++L + K++ S+ ++ L+ LE +
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067
Query: 115 NATVVSLQQALGKAEMLCSTLKKQMK-YLEQQQDETKQAQEEARRLRSKMKTMEQIELLL 173
+ + LQ + + +M + +++++ L + DE Q +++R + ++ L
Sbjct: 1068 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1127
Query: 174 QSQRP---EVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADK-LRKDL 229
S+R + E+ RD+G A++ + + L+ R+ V K L ++
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1187
Query: 230 FSSRSKLQTVYSELDQAKLELKSAQKDLQSA----DKEIMSLKKKLTMLQETLNLPPVAS 285
S +++Q + + QA EL + + A DK +L+K+ L L + A
Sbjct: 1188 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAK 1247
Query: 286 ETVDRLVLESPAPVE 300
+ V+ + A V+
Sbjct: 1248 QEVEHKKKKLEAQVQ 1262
Score = 43.1 bits (100), Expect = 5e-04
Identities = 28/147 (19%), Positives = 76/147 (51%), Gaps = 4/147 (2%)
Query: 137 KQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQ 196
+Q + ++ ++DE ++ +E ++ +++K +EQ L ++ ++E ++ + E+
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908
Query: 197 LAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKD 256
+ V + K+E E + +A E + + L + R K+ +L++ E ++A++
Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968
Query: 257 LQ----SADKEIMSLKKKLTMLQETLN 279
LQ +A+ +I L+ ++ ++ + N
Sbjct: 969 LQLEKVTAEAKIKKLEDEILVMDDQNN 995
Score = 40.4 bits (93), Expect = 0.003
Identities = 57/251 (22%), Positives = 106/251 (42%), Gaps = 32/251 (12%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
++++ + AQ+ + + D + L D + + V S+ L +AE L K
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 139 MKYLEQQQDETKQA-QEEARR---LRSKMKTMEQIELLLQSQRPE-------VEEMIRDM 187
+ L Q +T++ QEE R+ + +K++ +E+ LQ Q E +E I +
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369
Query: 188 GVG-----------QSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
+ S VE L +KE ENL + + DKL K ++++L
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK----TKNRL 1425
Query: 237 QTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESP 296
Q ELD ++L + ++ + + +K+ +K +L E N+ ++ DR E+
Sbjct: 1426 Q---QELDDLVVDLDNQRQLVSNLEKK---QRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
Query: 297 APVEVNLKLRR 307
L L R
Sbjct: 1480 EKETKALSLAR 1490
Score = 38.9 bits (89), Expect = 0.010
Identities = 51/215 (23%), Positives = 97/215 (45%), Gaps = 18/215 (8%)
Query: 90 LSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMK-YLEQQQDE 148
L K++ +R ++++ + D + ++ ++ + L K++ T ++MK LE+ +DE
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE-LEKSKRALETQMEEMKTQLEELEDE 1554
Query: 149 TKQAQEEARRLRSKMKTME-QIELLLQSQRPEVEEMIRDMGVGQSAVE--------QLAV 199
+ ++ RL M+ ++ Q E LQ++ + EE R + E Q A+
Sbjct: 1555 LQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1614
Query: 200 YCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKD--- 256
+ KK +LK+ + + A K R++ KLQ + Q +LE A +D
Sbjct: 1615 AAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDF-QRELEDARASRDEIF 1672
Query: 257 --LQSADKEIMSLKKKLTMLQETLNLPPVASETVD 289
+ +K+ SL+ L LQE L A + D
Sbjct: 1673 ATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD 1707
Score = 36.2 bits (82), Expect = 0.066
Identities = 44/220 (20%), Positives = 90/220 (40%), Gaps = 37/220 (16%)
Query: 75 DAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCST 134
+ E L + D+V + + +K KR + ++ ++ LEE + + + A + E+
Sbjct: 1512 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 135 LKKQMK-----------------------YLEQQQDETKQAQEEARRLRSKMKTMEQIEL 171
LK Q + Y + +DE KQ A + ++ +EL
Sbjct: 1572 LKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLEL 1631
Query: 172 LLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFS 231
S EE A++QL +K L++AR + E+ ++
Sbjct: 1632 QADSAIKGREE----------AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE---- 1677
Query: 232 SRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL 271
+ K +++ ++L Q + +L +A++ + AD E L ++L
Sbjct: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1717
Score = 34.7 bits (78), Expect = 0.19
Identities = 35/187 (18%), Positives = 85/187 (45%), Gaps = 10/187 (5%)
Query: 90 LSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDET 149
L Q +++ + Q D L+ T E + L++ K L + L+ + +
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 150 KQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYE 209
+A+E RL +K + +E+I ++++ E E+ + + Q+ +++A + L+++ E
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL---QAERKKMAQQMLDLEEQLE 960
Query: 210 NLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKK 269
+ AR+ KL+ + ++ +K++ + E+ + K+ + ++ I L
Sbjct: 961 EEEAARQ-------KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013
Query: 270 KLTMLQE 276
L +E
Sbjct: 1014 NLAEEEE 1020
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 54.7 bits (130), Expect = 2e-07
Identities = 44/203 (21%), Positives = 97/203 (47%), Gaps = 17/203 (8%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
LK++++ + L ++DK ++ Q ++ L ++ LQQA K ++ S
Sbjct: 754 LKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEG---ELQQASAKLDVFQS----- 805
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVE-QL 197
Y ++TK +E+ +L+ K+ +E +LL Q EVE +D+ A + Q+
Sbjct: 806 --YQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV 863
Query: 198 AVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDL 257
L+K+ +++ K+ +V + +D + + + + E + L+++ QK
Sbjct: 864 QDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQK-- 921
Query: 258 QSADKEIMSLKKKLTMLQETLNL 280
KEI L +KL+ ++++++
Sbjct: 922 ----KEIEILTQKLSAKEDSIHI 940
Score = 51.6 bits (122), Expect = 2e-06
Identities = 67/291 (23%), Positives = 132/291 (45%), Gaps = 35/291 (12%)
Query: 48 QCRIQVGKRTIINKLFFDLAQEEENVLDAEF-----LKNELDNVRAQLSQKDKEKRDSQV 102
QC + ++ + + + QE E + D L +L + + + Q +++K V
Sbjct: 308 QCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDK--GMV 365
Query: 103 IIDTLR---DTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDE-------TKQA 152
I +T R +TLE + + L+ + + L++Q + E+ E T Q
Sbjct: 366 IAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQK 425
Query: 153 QEEARR-LRSKM--------KTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVS 203
EEARR L+++M KT E+ + LQ + V++ + D+ + +S+ EQ+A
Sbjct: 426 TEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDV-MKKSSEEQIA----K 480
Query: 204 LKKEYENLKEARKASGEVADKL--RKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSAD 261
L+K +E KE + E+ KL R+ F + K+ S+ + K+ + Q++ + +
Sbjct: 481 LQKLHE--KELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALE 538
Query: 262 KEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRRPSFRD 312
+ + K LT + L +ET +LE + +E +L+ + +D
Sbjct: 539 ELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKD 589
Score = 42.7 bits (99), Expect = 7e-04
Identities = 41/190 (21%), Positives = 93/190 (48%), Gaps = 18/190 (9%)
Query: 80 KNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQM 139
+N + ++ QL K KE + I+ L++ L+++N L+ G+ E S ++K+
Sbjct: 1457 QNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLK---GEMEDDKSKMEKKE 1513
Query: 140 KYLEQQ-QDETKQAQEEARRLRSKMKTMEQIELLLQS--QRPEVEEMIRDMGVGQSAVEQ 196
LE + + +T + E + K +E + +L++ Q+ ++E + V++
Sbjct: 1514 SNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEH--------KELVQK 1565
Query: 197 LAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKD 256
L + +++ +KEA E L ++S +++L+T EL+ L +KS +++
Sbjct: 1566 LQHFQELGEEKDNRVKEAE----EKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEE 1621
Query: 257 LQSADKEIMS 266
L++ + + S
Sbjct: 1622 LKALEDRLES 1631
Score = 40.8 bits (94), Expect = 0.003
Identities = 57/237 (24%), Positives = 108/237 (45%), Gaps = 23/237 (9%)
Query: 97 KRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEA 156
K++ + + D ++ TL+E+ T L+Q K + L S L +Q + + +E E+
Sbjct: 1828 KQNLENVFDDVQKTLQEKELTCQILEQ---KIKELDSCLVRQKEVHRVEMEELTSKYEKL 1884
Query: 157 RRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARK 216
+ L+ + ELL ++ EE + V + + L+ + + ++
Sbjct: 1885 QALQQMDGRNKPTELLEEN----TEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQ 1940
Query: 217 ASGEVADKLRKDLFSSR----SKLQTVYSELDQAKLE-LKSAQKDLQ----SADKEIM-- 265
G+ +L+KDL R +L+ + E DQ + E +K Q+DL+ S K++M
Sbjct: 1941 KLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMRE 2000
Query: 266 ---SLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRRPSFRDDIDLNAT 319
L +K L+ T+ ++ V+ +LES E N L++ + +DD DL T
Sbjct: 2001 FNTQLAQKEQELEMTIKETINKAQEVEAELLESHQE-ETNQLLKKIAEKDD-DLKRT 2055
Score = 39.7 bits (91), Expect = 0.006
Identities = 46/210 (21%), Positives = 96/210 (45%), Gaps = 23/210 (10%)
Query: 70 EENVLDAEF-LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKA 128
++ +LD E LK EL+N +LSQK+K+ LE A + A+ +
Sbjct: 971 KKKLLDQEAKLKKELENTALELSQKEKQFNAKM---------LEMAQANSAGISDAVSRL 1021
Query: 129 EMLCSTLKKQMKYLEQ--QQDETKQAQEEARRLRSKMKTMEQI-ELLLQSQRPEVEEMIR 185
E + K+Q++ L + +++ ++L + + +++I E+ LQ + EV E+ +
Sbjct: 1022 E---TNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQ 1078
Query: 186 DMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQ 245
+ + E+ + KE LKE ++L++ L + + ++ + +
Sbjct: 1079 KILLFGCEKEE-------MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETK 1131
Query: 246 AKLELKSAQKDLQSADKEIMSLKKKLTMLQ 275
K L+ + DL + KE L+++L L+
Sbjct: 1132 LKAHLEKLEVDLNKSLKENTFLQEQLVELK 1161
Score = 36.2 bits (82), Expect = 0.066
Identities = 24/119 (20%), Positives = 53/119 (44%)
Query: 148 ETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKE 207
+T E +LR + + + Q ++EE + ++ +E L +L+KE
Sbjct: 1267 KTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKE 1326
Query: 208 YENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMS 266
N ++A +L+K+L + + + + EL + K+E+ S K L + ++ +
Sbjct: 1327 GGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN 1385
Score = 36.2 bits (82), Expect = 0.066
Identities = 37/170 (21%), Positives = 78/170 (45%), Gaps = 13/170 (7%)
Query: 107 LRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTM 166
LR EE+N +S QQA + E + +K +E E + Q+E ++ +
Sbjct: 1278 LRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEG---GNQQQAA 1334
Query: 167 EQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLR 226
+ E + + E+ E I + + + +++ V SL K+ +L + S +++K
Sbjct: 1335 SEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEK-- 1392
Query: 227 KDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
+ + ++ + D+ K EL +DL S + +S K+K++ L++
Sbjct: 1393 ------EAAISSLRKQYDEEKCELLDQVQDL-SFKVDTLS-KEKISALEQ 1434
Score = 35.8 bits (81), Expect = 0.086
Identities = 53/233 (22%), Positives = 99/233 (42%), Gaps = 27/233 (11%)
Query: 55 KRTIINKLFFDLAQ--EEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLE 112
K +++L L Q EE+N L+ F QL +K+ + + + I++L E
Sbjct: 1267 KTCTVSELEAQLRQLTEEQNTLNISF-----QQATHQLEEKENQIKSMKADIESLVTEKE 1321
Query: 113 ERNATVVSLQQALGKAEMLCSTLKKQM----KYLEQQQDETKQAQEEARRLRSKMK---- 164
+ QQA + E + LKK++ + ++E K+ + E L ++
Sbjct: 1322 ALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNV 1381
Query: 165 ------TMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKAS 218
++ + E + S R + +E ++ V+ L+ +L KE + E
Sbjct: 1382 QLQNSISLSEKEAAISSLRKQYDEEKCEL---LDQVQDLSFKVDTLSKEKISALEQVDDW 1438
Query: 219 GEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKL 271
+ +K S ++ Q EL Q +LELKS K+ D++I LK++L
Sbjct: 1439 SNKFSEWKKKAQSRFTQHQNTVKEL-QIQLELKS--KEAYEKDEQINLLKEEL 1488
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 54.3 bits (129), Expect = 2e-07
Identities = 60/248 (24%), Positives = 110/248 (44%), Gaps = 27/248 (10%)
Query: 68 QEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALG- 126
Q E + +A L+ +L N+R +Q D E+ + + I +++ L E N +++
Sbjct: 1449 QAEVSKNNALQLREKLGNIR---NQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANG 1505
Query: 127 --------KAEMLCSTLKKQMKYLEQQQD---ETKQAQEEA---RRLRSKMKTMEQ---I 169
++ L L K K+++ +D + + EEA ++L K K E+ I
Sbjct: 1506 VLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAANI 1565
Query: 170 ELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKK---EYENLKEARKASGEVADK-- 224
L L ++++ G S + QL +KK + EN K+ E+A +
Sbjct: 1566 LLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQRS 1625
Query: 225 -LRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPV 283
L L ++KLQ AK++ +SAQ S +KE + LKK+ +LQ + +
Sbjct: 1626 GLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKTSTTGL 1685
Query: 284 ASETVDRL 291
ET+ ++
Sbjct: 1686 TKETLGKV 1693
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 54.3 bits (129), Expect = 2e-07
Identities = 48/189 (25%), Positives = 98/189 (51%), Gaps = 29/189 (15%)
Query: 74 LDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCS 133
++ + L+ L+N ++ Q + E +D ++ TL+ LEE + L+Q
Sbjct: 763 IENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQ---------- 812
Query: 134 TLKKQMKYLEQQ----QDETKQAQEEARRLRS----KMKTMEQIELLLQSQRPEVEEMIR 185
L+K+ K LEQ+ + + KQ ++E +RLR K T+E+ + + + E + + +
Sbjct: 813 -LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Query: 186 DMGVGQSAVEQLAVYCVSLKK-EYENLKEARKASGEVAD--KLRKDLFSSRSKLQTVYSE 242
++G+ + + CV LK+ E EN + ++A+ ++ LR+DL S + K Q + ++
Sbjct: 872 EIGIYKES-------CVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNND 924
Query: 243 LDQAKLELK 251
L++ EL+
Sbjct: 925 LEKLTHELE 933
Score = 50.1 bits (118), Expect = 4e-06
Identities = 55/223 (24%), Positives = 105/223 (47%), Gaps = 18/223 (8%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQA 124
+L +E AE L+NEL ++ + K+ + ++ + + + LE+ N+ L++
Sbjct: 616 ELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI-EALEQENS---ELERE 671
Query: 125 LGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMI 184
K + + K LE + E Q EE LR +++++ + + + E +E+
Sbjct: 672 NRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKEL- 730
Query: 185 RDMGVGQSAVEQLAVYCVSLK---KEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYS 241
+S EQL LK K+ E L+ + + +L+K L +S K+Q + S
Sbjct: 731 ------ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 242 ELDQAKLELKSAQKDLQS---ADKEIMSLKKKLTML-QETLNL 280
EL ++E ++ QK+L+ + K + L+K+ L QET L
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQL 827
Score = 47.0 bits (110), Expect = 4e-05
Identities = 52/227 (22%), Positives = 102/227 (44%), Gaps = 14/227 (6%)
Query: 106 TLRDTLEERNATVVSLQ---QALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRL-RS 161
+L T+EE TV S++ + K E L K+++ LE + + KQ+ + + L +
Sbjct: 471 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 530
Query: 162 KMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEV 221
MK Q+E +++ R E I+ + + E L SL++ + EAR E
Sbjct: 531 LMKEKAQLEKTIETLRENSERQIKIL---EQENEHLNQTVSSLRQRSQISAEARVKDIEK 587
Query: 222 ADKLR----KDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQET 277
+K+ K+ S SK++ ++ + K + + + E+ L+K+ +LQ+
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Query: 278 LNLPPVASETVDRLVLESPAPVEVNLKLRRPSFRDDIDLNATFDVDT 324
+ + E ++ L E+ N KL++ D N TF +++
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTL---DSFKNLTFQLES 691
Score = 45.8 bits (107), Expect = 8e-05
Identities = 52/246 (21%), Positives = 115/246 (46%), Gaps = 19/246 (7%)
Query: 82 ELDNVRAQLSQKDKEKRDSQVIIDTLRDT------LEERNATVVSLQQALGKA-EMLCST 134
+L+++ + SQ D+E + + +++L+ L+ N + S ++ L K E+L ++
Sbjct: 688 QLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKAS 747
Query: 135 LKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPE---VEEMIRDMGVGQ 191
KK + Q + Q + L + K ++Q+E LQ E +++ + ++ +
Sbjct: 748 FKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS 807
Query: 192 SAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELK 251
+EQL SL++E L++ +K +L K+ R + + + L++ +++
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKK-------QLEKENKRLRQQAEIKDTTLEENNVKIG 860
Query: 252 SAQKDLQSADKEIMSLKKKLTMLQ--ETLNLPPVASETVDRLVLESPAPVEVNLKLRRPS 309
+ +K+ ++ KEI K+ L+ E N V T+D L + V+ KL+
Sbjct: 861 NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQ 920
Query: 310 FRDDID 315
+D++
Sbjct: 921 MNNDLE 926
Score = 43.1 bits (100), Expect = 5e-04
Identities = 58/241 (24%), Positives = 117/241 (48%), Gaps = 32/241 (13%)
Query: 76 AEFLKNELDNVRAQLSQKDK--------EKRDSQVIIDTLRDTLEERNATVVSLQQALGK 127
++ LK E +N R LS+K + EK+ Q + +D ++E+ L++ +
Sbjct: 491 SKILKMEKENQR--LSKKVEILENEIVQEKQSLQNCQNLSKDLMKEK----AQLEKTI-- 542
Query: 128 AEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDM 187
E L ++Q+K LEQ+ + Q R+ RS++ +++ + + + + E I++
Sbjct: 543 -ETLRENSERQIKILEQENEHLNQTVSSLRQ-RSQISAEARVKDI-EKENKILHESIKET 599
Query: 188 GVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAK 247
S + ++ +KKE E+ KE GE A++L +L + +EL Q K
Sbjct: 600 S---SKLSKIEFEKRQIKKELEHYKE----KGERAEELENELHHLEKE-----NELLQKK 647
Query: 248 L-ELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLR 306
+ LK + +++ ++E L+++ L++TL+ + ++ L E+ E NL+LR
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Query: 307 R 307
R
Sbjct: 708 R 708
Score = 31.6 bits (70), Expect = 1.6
Identities = 45/221 (20%), Positives = 93/221 (42%), Gaps = 40/221 (18%)
Query: 89 QLSQKDKEKRD----SQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKK------Q 138
+L + +KE ++ + + I TL E+ + + QQ E L L+K +
Sbjct: 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER 941
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLA 198
+ + EQ D+++ E++ + K++E E + + +EE + +QL
Sbjct: 942 LLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEE-------STNYNQQLR 994
Query: 199 VYCVSLKKEYENLKEARKA----------SGE------VADKLRKDLFSSRSKL------ 236
++KK YE LK+ + SGE + + ++L + +L
Sbjct: 995 QELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN 1054
Query: 237 -QTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
T+ +E K +LK + + +I++L+++ LQE
Sbjct: 1055 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQE 1095
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 54.3 bits (129), Expect = 2e-07
Identities = 49/255 (19%), Positives = 116/255 (45%), Gaps = 24/255 (9%)
Query: 74 LDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCS 133
L+ + +EL+ V+ + +KDKEK ++ L LE + + L + +
Sbjct: 372 LNFSAMASELEEVKRCMERKDKEKAHLASQVENLTRELENGEKQQLQMLDRLKEIQNHFD 431
Query: 134 TLKKQMKYLEQQ--------QDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIR 185
T + + K+ + Q +D TKQA+ L+ E+ E + + + +E IR
Sbjct: 432 TCEAERKHADLQISELTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIR 491
Query: 186 DMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEV---ADKLRKDLFSSRSKLQTVYSE 242
+ +E+ +L+K+ E + E + ++ D+L+ L+++ +++ + E
Sbjct: 492 QWKLKHKKLER------ALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKE 545
Query: 243 LDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQ-ETLNLPPVASETVDRL--VLESPAPV 299
L+ + +++L S ++++ +K L+ E N + +T+ RL L+ + +
Sbjct: 546 LNDVLTKRALQEEELHSKEEKLRDIKSHQADLELEVKN----SLDTIHRLESELKKQSKI 601
Query: 300 EVNLKLRRPSFRDDI 314
+ +K+ + ++I
Sbjct: 602 QSQMKVEKAHLEEEI 616
Score = 47.4 bits (111), Expect = 3e-05
Identities = 47/208 (22%), Positives = 94/208 (45%), Gaps = 12/208 (5%)
Query: 77 EFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLK 136
E LK++ D + +L+Q + E + ++ L+D LEER + ++ L + E LK
Sbjct: 755 EKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQLEEREKHISIEEEHLRRMEEARLQLK 814
Query: 137 KQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIE-LLLQSQRPEVE-EMIRDMGVGQSAV 194
Q+ LE +Q+ + K + + +E L + S P++ + R + ++ +
Sbjct: 815 DQLLCLETEQESILGVIGKEIDAACKTFSKDSVEKLKVFSSGPDIHYDPHRWLAESKTKL 874
Query: 195 EQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSE-------LDQAK 247
+ L C LK+ K R +LR + S+LQ ++ + LD+
Sbjct: 875 QWL---CEELKERENREKNLRHQLMLCRQQLRNLTENKESELQCLFQQIERQEQLLDEIH 931
Query: 248 LELKSAQKDLQSADKEIMSLKKKLTMLQ 275
E + ++ Q D+E+ SL+ ++ L+
Sbjct: 932 REKRDLLEETQRKDEEMGSLQDRVIALE 959
Score = 44.3 bits (103), Expect = 2e-04
Identities = 45/195 (23%), Positives = 87/195 (44%), Gaps = 25/195 (12%)
Query: 77 EFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLK 136
E L+ EL++V + + +++E + + LRD + + ++ +L L S LK
Sbjct: 540 ENLRKELNDVLTKRALQEEELHSKE---EKLRDIKSHQADLELEVKNSLDTIHRLESELK 596
Query: 137 KQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQ 196
KQ K Q + E +EE L+ K + ++ +LL E++E I+D+
Sbjct: 597 KQSKIQSQMKVEKAHLEEEIAELK-KSQAQDKAKLL------EMQESIKDLS-------- 641
Query: 197 LAVYCVSLKKEYEN-LKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQK 255
+++ + N L E +A V L ++S+ + + + Q KLE Q+
Sbjct: 642 ------AIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEETATIITQLKLERDVHQR 695
Query: 256 DLQSADKEIMSLKKK 270
+L+ + S+K K
Sbjct: 696 ELKDLTSSLQSVKTK 710
Score = 42.7 bits (99), Expect = 7e-04
Identities = 50/227 (22%), Positives = 99/227 (43%), Gaps = 20/227 (8%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
+KN+L + +Q ++E S+ +++ + E V L+ L KAE L+ Q
Sbjct: 270 IKNKLRQTETEKNQLEQELELSRRLLNQSEGSRETLLHQVEELRTQLTKAEGDRKGLQHQ 329
Query: 139 MKYLEQQQDETKQAQEEARRLRSKMKTMEQ----------IELLLQSQRPEVEEMIRDMG 188
+ + +QQ + Q E R R ++ +Q ++L + E+EE+ R M
Sbjct: 330 VSQISKQQSNYQDEQGEDWRFRRGVEREKQDLEKQMSDLRVQLNFSAMASELEEVKRCME 389
Query: 189 VGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKL 248
LA +L +E EN K ++ D+L++ ++ T +E A L
Sbjct: 390 RKDKEKAHLASQVENLTRELEN---GEKQQLQMLDRLKE----IQNHFDTCEAERKHADL 442
Query: 249 ELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLES 295
++ + + A K+ ++ L+ LQ++ L A + + L L++
Sbjct: 443 QISELTRHAEDATKQ---AERYLSELQQSEALKEEAEKRREDLKLKA 486
Score = 37.4 bits (85), Expect = 0.029
Identities = 42/213 (19%), Positives = 96/213 (45%), Gaps = 10/213 (4%)
Query: 66 LAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQAL 125
L + E + +A+ + D V +L + ++E R + +++ +D L + LQ+AL
Sbjct: 200 LEELTEKLNEAQKQEVVSDRVERRLQELEREMRTERELVERRQDQL---GLMSLQLQEAL 256
Query: 126 GKAEMLCS----TLKKQMKYLEQQQDETKQAQEEARRLRSKMK-TMEQIELLLQSQRPEV 180
K E +K +++ E ++++ +Q E +RRL ++ + + E + ++ R ++
Sbjct: 257 KKQEAKADEHEGAIKNKLRQTETEKNQLEQELELSRRLLNQSEGSRETLLHQVEELRTQL 316
Query: 181 EEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL--QT 238
+ D Q V Q++ + + E R+ L K + R +L
Sbjct: 317 TKAEGDRKGLQHQVSQISKQQSNYQDEQGEDWRFRRGVEREKQDLEKQMSDLRVQLNFSA 376
Query: 239 VYSELDQAKLELKSAQKDLQSADKEIMSLKKKL 271
+ SEL++ K ++ K+ ++ +L ++L
Sbjct: 377 MASELEEVKRCMERKDKEKAHLASQVENLTREL 409
Score = 35.8 bits (81), Expect = 0.086
Identities = 40/199 (20%), Positives = 88/199 (44%), Gaps = 23/199 (11%)
Query: 85 NVRAQLSQKDKEKRDSQVIIDTLR-DTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLE 143
N++ + KEK +++ I TL+ ++LEE+N + Q L K + C L +++ E
Sbjct: 714 NIQELMKHFKKEKSEAENHIRTLKAESLEEKNMAKIHRGQ-LEKLKSQCDRLTEELTQNE 772
Query: 144 QQQDETK--------QAQEEARRL---RSKMKTMEQIELLLQSQ----RPEVEEMIRDMG 188
+ + K Q +E + + ++ ME+ L L+ Q E E ++ +G
Sbjct: 773 NENKKLKLKYQCLKDQLEEREKHISIEEEHLRRMEEARLQLKDQLLCLETEQESILGVIG 832
Query: 189 VGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKL 248
+++ C + K+ + + ++ + L S++KLQ + EL + +
Sbjct: 833 ------KEIDAACKTFSKDSVEKLKVFSSGPDIHYDPHRWLAESKTKLQWLCEELKEREN 886
Query: 249 ELKSAQKDLQSADKEIMSL 267
K+ + L +++ +L
Sbjct: 887 REKNLRHQLMLCRQQLRNL 905
Score = 33.1 bits (74), Expect = 0.56
Identities = 33/179 (18%), Positives = 77/179 (43%), Gaps = 25/179 (13%)
Query: 120 SLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPE 179
SL+ + L +++ + ETK+A EE L K+ ++ E++
Sbjct: 167 SLRDLSSEQIRLGDDFNRELSRRSRSDAETKRALEE---LTEKLNEAQKQEVVSDRVERR 223
Query: 180 VEEMIRDMGVGQSAVE----QLAVYCVSLKKEYENLK-EARKASGEVADKLRKD------ 228
++E+ R+M + VE QL + + L++ + + +A + G + +KLR+
Sbjct: 224 LQELEREMRTERELVERRQDQLGLMSLQLQEALKKQEAKADEHEGAIKNKLRQTETEKNQ 283
Query: 229 -----------LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
L S +T+ ++++ + +L A+ D + ++ + K+ + Q+
Sbjct: 284 LEQELELSRRLLNQSEGSRETLLHQVEELRTQLTKAEGDRKGLQHQVSQISKQQSNYQD 342
>gi|31542661 transmembrane protein 57 [Homo sapiens]
Length = 664
Score = 53.9 bits (128), Expect = 3e-07
Identities = 63/289 (21%), Positives = 127/289 (43%), Gaps = 35/289 (12%)
Query: 52 QVGKRTIINKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTL 111
Q+ K + +L D+ + + ++ + ++ EL + + LS ++ R + + L
Sbjct: 376 QLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELL 435
Query: 112 EERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDET-KQAQEEARRLRSKMKTMEQIE 170
+ + V ++Q K + S L+K++K ++ + KQ EE +R + + T +
Sbjct: 436 QNKLHNAVQMKQ---KDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAV 492
Query: 171 LLLQSQRPEVEEMIR---------------DMGVGQSAVEQLAVYCVSLKKEYENLKEAR 215
+ R E E +R DM V + + +L + L+K EN K+
Sbjct: 493 AFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTE 552
Query: 216 ---KASGEVADKLR--KDLFSSRSKLQT-VYSELDQAKLELKSAQKDLQSADKEIMSLKK 269
A + DK + ++ S+ ++++ ++S L AK +L+ AQ + D+EI LK+
Sbjct: 553 VLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQ 612
Query: 270 K----------LTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRRP 308
K +T T L PV+ + V SP+ ++ N + +P
Sbjct: 613 KIAEVMAVMPSITYSAATSPLSPVSPHYSSKFVETSPSGLDPNASVYQP 661
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 53.5 bits (127), Expect = 4e-07
Identities = 54/263 (20%), Positives = 116/263 (44%), Gaps = 13/263 (4%)
Query: 65 DLAQEEENVLDAEFLKNELDNVRAQLSQ-KDKEKRDSQVIIDTLRDTLEERNATVVSLQQ 123
D+ Q++ + K +L+ Q++Q + +E + +D T++++N + L+Q
Sbjct: 1429 DIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ 1488
Query: 124 ALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQ--IELLLQSQRPEVE 181
+ K L+ + L++ Q + ++A A +K+K EQ L + +R E
Sbjct: 1489 LIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQE 1548
Query: 182 EMIRDMGVG--QSAVEQLAVYCVSLKKEYENLKEA-------RKASGEVADKLRKDLFSS 232
++D + Q+++++L + +++E LK RK E + +R+ L
Sbjct: 1549 RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ 1608
Query: 233 RSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLV 292
K+ + +L+QA + K ++ DL+ + ++ QE L E + R +
Sbjct: 1609 AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL 1668
Query: 293 LESPAPVEVNLKLRRPSFRDDID 315
L+ V+ LR F+ I+
Sbjct: 1669 LQEQESVK-QAHLRNEHFQKAIE 1690
Score = 47.4 bits (111), Expect = 3e-05
Identities = 51/231 (22%), Positives = 106/231 (45%), Gaps = 29/231 (12%)
Query: 70 EENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAE 129
+E L + ++ EL+ ++ S+ +++ + ++ +R +L+E+ + +L Q L +A
Sbjct: 1564 KELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQAS 1623
Query: 130 MLCST----LKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQ--------- 176
++ L++Q L+ E ++ QEE RRL S+++ + + LLQ Q
Sbjct: 1624 IVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRR--QLLQEQESVKQAHLR 1681
Query: 177 ----RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSS 232
+ +E+ R + + +E+L +L KE+ L+E + D LR+ +
Sbjct: 1682 NEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEA 1741
Query: 233 RSKLQTVYSEL-------DQAKLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
S EL + LEL+ DLQ +E +L++++ Q+
Sbjct: 1742 DSDKNATILELRSQLQISNNRTLELQGLINDLQ---RERENLRQEIEKFQK 1789
Score = 40.8 bits (94), Expect = 0.003
Identities = 60/284 (21%), Positives = 123/284 (43%), Gaps = 36/284 (12%)
Query: 80 KNELDNVRAQLSQKDKEKRDSQVIIDTLRDTL-----EERNATVVSLQQALGKAEMLCST 134
+++ N+R QL + +E RD + I L D++ + R A +LQQ +E++
Sbjct: 1229 EDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIM--- 1285
Query: 135 LKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAV 194
KKQ +E +Q +++++ AR +S +E+ +Q + E+E + + Q
Sbjct: 1286 QKKQHLEIELKQVMQQRSEDNARHKQS----LEEAAKTIQDKNKEIERLKAEF---QEEA 1338
Query: 195 EQLAVYCVSLKKEYEN-LKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSA 253
++ + EYEN L + R E L+ + + +T +L K E S
Sbjct: 1339 KR--------RWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSG 1390
Query: 254 QK-DLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRRPSFRD 312
+ + + +E SL +++ L+ TL ++T + L VE +++ ++ + +
Sbjct: 1391 YRAQIDNLTRENRSLSEEIKRLKNTL------TQTTENL-----RRVEEDIQQQKATGSE 1439
Query: 313 DIDLNATFDVDTPPARPSSSQHGYYEKLCLEKSHSPIQDVPKKI 356
+V+ ++ K L+ + IQD K+I
Sbjct: 1440 VSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEI 1483
Score = 38.9 bits (89), Expect = 0.010
Identities = 41/215 (19%), Positives = 91/215 (42%), Gaps = 21/215 (9%)
Query: 70 EENVLDAEFLKN---ELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALG 126
+E+++ E L+N E D++R S+ D +K + I LR L+ N + LQ +
Sbjct: 1715 KEHLMLEEELRNLRLEYDDLRRGRSEADSDKNAT---ILELRSQLQISNNRTLELQGLIN 1771
Query: 127 KAEMLCSTLKKQMKYLEQQ-----------QDETKQAQEEARRLRSKMKTMEQIELLLQS 175
+ L+++++ ++Q +++ Q +E L K+K +EQ + LQ
Sbjct: 1772 DLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQR 1831
Query: 176 QRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSK 235
E+ + ++L ++ + K E K+ + S +
Sbjct: 1832 LEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSERE 1891
Query: 236 LQTVYSELDQAKLELK----SAQKDLQSADKEIMS 266
++ SE+++ + E+K ++ L+ + +E S
Sbjct: 1892 KNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQS 1926
Score = 33.1 bits (74), Expect = 0.56
Identities = 44/204 (21%), Positives = 90/204 (44%), Gaps = 27/204 (13%)
Query: 81 NELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMK 140
NE N+ +++S K + + Q I + +++++ + S L +L +K+ M
Sbjct: 928 NEQKNLHSEISGKRDKSEEVQKIAELCANSIKDYELQLASYTSGL--ETLLNIPIKRTMI 985
Query: 141 YLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVY 200
Q + +EA + ++ IELL +S + R + ++E L +
Sbjct: 986 -----QSPSGVILQEAADVHARY-----IELLTRSG-----DYYRFLSEMLKSLEDLKLK 1030
Query: 201 CVSLKKEYENLKEARKASGEVADK----------LRKDLFSSRSKLQTVYSELDQAKLEL 250
++ E L+ AR A+ E +K + + ++KL ++ QA+L+
Sbjct: 1031 NTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQAELDG 1090
Query: 251 KSAQKDLQSADKEIMSLKKKLTML 274
KSA+++L +I L +K+T L
Sbjct: 1091 KSAKQNLDKCYGQIKELNEKITRL 1114
Score = 32.0 bits (71), Expect = 1.2
Identities = 37/168 (22%), Positives = 77/168 (45%), Gaps = 12/168 (7%)
Query: 109 DTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQ 168
+ L+ +N + L++ L A S + K+L+Q ++ Q E + ++K+ ++E+
Sbjct: 1025 EDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQN---LQKYQAECSQFKAKLASLEE 1081
Query: 169 IELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD 228
++ + ++ + D GQ +++L L E E+ K RK+ + D+ + D
Sbjct: 1082 LKRQAELDGKSAKQNL-DKCYGQ--IKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKND 1138
Query: 229 LFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
+ Q L KLE ++K ++ + EI L+ +LQE
Sbjct: 1139 YDQLQKARQCEKENLGWQKLE---SEKAIKEKEYEIERLR---VLLQE 1180
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 53.5 bits (127), Expect = 4e-07
Identities = 51/225 (22%), Positives = 102/225 (45%), Gaps = 36/225 (16%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L ++DN++ + +KEK + ++ ID L ++E S+ ++ E +C TL+ Q
Sbjct: 1204 LGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME-------SVSKSKANLEKICRTLEDQ 1256
Query: 139 MKYLEQQQDETK---------------QAQEEARRLRSKMKTMEQIELLLQSQRPEVEEM 183
+ + +E + +A E +R+L K + Q+ Q+ + EE+
Sbjct: 1257 LSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEEL 1316
Query: 184 IRDMGVGQSAVEQLAVY-------CVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
R + A LA C L+++YE +E + K ++ R+K
Sbjct: 1317 KRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1376
Query: 237 QT----VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQET 277
+T EL++AK +L AQ+ LQ +++++ ++ K L++T
Sbjct: 1377 ETDAIQRTEELEEAKKKL--AQR-LQDSEEQVEAVNAKCASLEKT 1418
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/215 (25%), Positives = 93/215 (43%), Gaps = 20/215 (9%)
Query: 60 NKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVV 119
N L + E EN+LDAE ++L + QL K KE + + EE NA +
Sbjct: 886 NDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKE-------VTERAEDEEEINAELT 938
Query: 120 SLQQALGKAEMLCSTLKKQMKYLE----QQQDETKQAQEEARRLRSKMKTMEQIELLLQS 175
+ ++ K E CS LKK + LE + + E + + + L ++ +++ L
Sbjct: 939 AKKR---KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTR 995
Query: 176 QRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSK 235
++ ++E + A E K + E E ++S E KLR DL ++ K
Sbjct: 996 EKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055
Query: 236 LQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKK 270
L+ +L A+ + + D Q D+ LKKK
Sbjct: 1056 LE---GDLKLAQESILDLENDKQQLDER---LKKK 1084
Score = 47.0 bits (110), Expect = 4e-05
Identities = 57/241 (23%), Positives = 106/241 (43%), Gaps = 29/241 (12%)
Query: 61 KLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEK-------RDSQVIIDTLRDTLEE 113
KL DL +E++LD E K +LD +L +KD E D Q + + ++E
Sbjct: 1055 KLEGDLKLAQESILDLENDKQQLDE---RLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKE 1111
Query: 114 RNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLL 173
A + L++ + + +KQ ++ +E + EEA + T QIEL
Sbjct: 1112 LQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGV-----TSTQIEL-- 1164
Query: 174 QSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSR 233
+++ E E + + ++ ++ A+ KK +++ E GE D L++ +
Sbjct: 1165 -NKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAEL----GEQIDNLQR----VK 1215
Query: 234 SKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVL 293
KL+ SE KLE+ ++S K +L+K L++ L+ +E + R +
Sbjct: 1216 QKLEKEKSEF---KLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS 1272
Query: 294 E 294
E
Sbjct: 1273 E 1273
Score = 45.8 bits (107), Expect = 8e-05
Identities = 55/245 (22%), Positives = 108/245 (44%), Gaps = 32/245 (13%)
Query: 66 LAQEEENVLDAEF----LKNELDNVRAQLSQKDKE----KRDSQVIIDTLRDTLEERNAT 117
L EE +L + +K+E+D ++++KD+E KR+ Q ++T++ L+ A
Sbjct: 1552 LEHEEAKILRIQLELTQVKSEIDR---KIAEKDEEIEQLKRNYQRTVETMQSALD---AE 1605
Query: 118 VVSLQQALGKAEMLCSTLKKQMKYLE-QQQDETKQAQEEARRLRSKMKTMEQIELLLQSQ 176
V S +A+ L ++ + +E Q +QA E + LRS ++ +L L
Sbjct: 1606 VRSRNEAI----RLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDA 1661
Query: 177 RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARK-ASGEVADKLRK-------- 227
E++ + + + L L+ E + ARK A E+ D +
Sbjct: 1662 LRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQN 1721
Query: 228 -DLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASE 286
L ++ KL+T +L Q + E++ A +D ++A+++ M+ E L S
Sbjct: 1722 TSLIHTKKKLET---DLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSA 1778
Query: 287 TVDRL 291
++R+
Sbjct: 1779 HLERM 1783
Score = 45.1 bits (105), Expect = 1e-04
Identities = 73/342 (21%), Positives = 142/342 (41%), Gaps = 41/342 (11%)
Query: 75 DAEFLKNELDNVRAQLSQKDKEKRDSQVIID----TLRDTLEERNATVVSLQQALGKAEM 130
DA EL+ + +L+Q+ ++ + ++ +L T + V L + +A
Sbjct: 1379 DAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANS 1438
Query: 131 LCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVG 190
L + L K+ + ++ E K EE++ ++E L+ R E+ +
Sbjct: 1439 LAAALDKKQRNFDKVLAEWKTKCEESQA---------ELEASLKESRSLSTELFKLKNAY 1489
Query: 191 QSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLEL 250
+ A++QL ++K+E +NL++ E+AD L + + + + + Q +LE
Sbjct: 1490 EEALDQLE----TVKRENKNLEQ------EIAD-LTEQIAENGKTIHELEKSRKQIELEK 1538
Query: 251 KSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVEVNLKLRRPSF 310
Q L+ A+ + + K+ +Q L L V SE +DR + E +E +L+R
Sbjct: 1539 ADIQLALEEAEAALEHEEAKILRIQ--LELTQVKSE-IDRKIAEKDEEIE---QLKRNYQ 1592
Query: 311 RDDIDLNATFDVD----TPPARPSSSQHGYYEKLCLEKSHSPIQDVPK----KICKGPRK 362
R + + D + R G ++ ++ SH+ Q + +G K
Sbjct: 1593 RTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLK 1652
Query: 363 ESQLSLGGQSCAGEPDEELVGAFPIFVRNAILGQKQPKRPRS 404
++QL L A E+L I R A L Q + + R+
Sbjct: 1653 DTQLHLDD---ALRGQEDLKEQLAIVERRANLLQAEVEELRA 1691
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/247 (20%), Positives = 110/247 (44%), Gaps = 35/247 (14%)
Query: 76 AEFLKNELDNVRAQLSQKDKEKR-DSQVIIDTLR--DTLEERNATVVSLQQALGKAEM-L 131
A L+ E++ +RA L Q ++ ++ Q ++D+ L +N +++ ++ L M L
Sbjct: 1679 ANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQL 1738
Query: 132 CSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQ 191
S ++ + +++ K+A +A + ++K + L+ + +E+ ++D+
Sbjct: 1739 QSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1798
Query: 192 SAVEQLAVYCVSLKKEYENLKE-----------ARKASGEVADKLRKDLFSSRSKLQTVY 240
EQLA+ KK+ + L+ +K + E LRK + R K T
Sbjct: 1799 DEAEQLAL--KGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRK--YERRVKELTYQ 1854
Query: 241 SE------------LDQAKLELKSAQKDLQSADKE----IMSLKKKLTMLQETLNLPPVA 284
SE +D+ ++++KS ++ + AD++ + +K L+E +A
Sbjct: 1855 SEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIA 1914
Query: 285 SETVDRL 291
V++L
Sbjct: 1915 ESQVNKL 1921
Score = 39.3 bits (90), Expect = 0.008
Identities = 37/151 (24%), Positives = 75/151 (49%), Gaps = 15/151 (9%)
Query: 136 KKQMKYLEQQQDETKQ--AQEEARR--LRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQ 191
+K+M ++++ +TK A+ EA+R L K+ T+ Q + LQ Q E + D +
Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD---AE 903
Query: 192 SAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSEL----DQAK 247
+QL L+ + + + E E +++ +L + + KL+ SEL D +
Sbjct: 904 ERCDQLIKAKFQLEAKIKEVTER----AEDEEEINAELTAKKRKLEDECSELKKDIDDLE 959
Query: 248 LELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
L L +K+ + + ++ +L ++L+ L ET+
Sbjct: 960 LTLAKVEKEKHATENKVKNLTEELSGLDETI 990
>gi|51317366 myosin XVIIIB [Homo sapiens]
Length = 2567
Score = 53.5 bits (127), Expect = 4e-07
Identities = 62/269 (23%), Positives = 119/269 (44%), Gaps = 62/269 (23%)
Query: 64 FDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNAT------ 117
F+ E+ + ++ EL ++ QL QK++E + ++ L+D E +
Sbjct: 1622 FEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGEN 1681
Query: 118 -VVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQ 176
V L++ L K E S+ +Q K QQ++ KQ ++ +R +++ M+Q+ Q
Sbjct: 1682 CVAGLKERLWKLE---SSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMH---QKD 1735
Query: 177 RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYEN----LKEARKASG------------- 219
R + EE + D V QS ++L + L++EYE L E + G
Sbjct: 1736 REDQEEELED--VRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD 1793
Query: 220 -EVADKLRKDL----------------------FSSRSKLQTVYSELDQAKLELKSAQK- 255
+V +LR+DL S+ +L+ V+S+L+Q++ + + A K
Sbjct: 1794 FDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKT 1853
Query: 256 ------DLQSADKEIMSLKKKLTMLQETL 278
DL+S E+ ++ + +++ E L
Sbjct: 1854 QKVLTADLESMHSELENMTRNKSLVDEQL 1882
Score = 42.4 bits (98), Expect = 0.001
Identities = 54/225 (24%), Positives = 100/225 (44%), Gaps = 29/225 (12%)
Query: 68 QEEENVLDAEFLKNELDNVRAQLSQKDKEKR-------DSQVIIDTLRDTLEERNATVVS 120
QEEE + + L + QL Q+ +EK+ D + +I TL D + R+ V
Sbjct: 1739 QEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEK 1798
Query: 121 -LQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKM-----------KTMEQ 168
L++ L + L S ++ + +E +T ++EE ++ S++ KT +
Sbjct: 1799 RLRRDLRRTHALLSDVQLLLGTMED--GKTSVSKEELEKVHSQLEQSEAKCEEALKTQKV 1856
Query: 169 IELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKD 228
+ L+S E+E M R+ + + +L L K + E + E+ K KD
Sbjct: 1857 LTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLK---RIDEDQDDLNELMQK-HKD 1912
Query: 229 LFSSRS----KLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKK 269
L + + ++Q + +L++AK E Q+ LQ A I L++
Sbjct: 1913 LIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQ 1957
Score = 34.3 bits (77), Expect = 0.25
Identities = 57/251 (22%), Positives = 100/251 (39%), Gaps = 54/251 (21%)
Query: 76 AEFLKNEL----DNVRAQLSQKDKEKRDSQVIIDTLRDTLE----ERNATVVSLQQALGK 127
+E L+NEL D + ++++ + D + D LE ER +Q+ K
Sbjct: 1421 SEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSK 1480
Query: 128 AEMLCSTLKKQMKYLEQQQDETKQ--------------------AQEEARRLRSKMKTME 167
E + L K LE+ Q + + AQ E LR K ++
Sbjct: 1481 HEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCAQMENEFLR---KRLQ 1537
Query: 168 QIELLLQSQRPEVEEMIRDMGVGQSAVE------------------QLAVYCVSLK---- 205
Q E L S+ +E+ + +G QSA + L CV L+
Sbjct: 1538 QCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQS 1597
Query: 206 KEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIM 265
+ +E K+ +K ++A L + +F + + V E + EL Q+ L+ ++E
Sbjct: 1598 RNHELEKKQKKFDLQLAQALGESVF-EKGLREKVTQENTSVRWELGQLQQQLKQKEQEAS 1656
Query: 266 SLKKKLTMLQE 276
LK+++ MLQ+
Sbjct: 1657 QLKQQVEMLQD 1667
>gi|150170725 zinc and ring finger 4 [Homo sapiens]
Length = 429
Score = 53.5 bits (127), Expect = 4e-07
Identities = 19/48 (39%), Positives = 28/48 (58%)
Query: 6 LCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQV 53
LC IC D ++ + + C HT+H +C+ WF AP R+CP C+ V
Sbjct: 308 LCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSV 355
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 53.5 bits (127), Expect = 4e-07
Identities = 51/225 (22%), Positives = 102/225 (45%), Gaps = 36/225 (16%)
Query: 79 LKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQ 138
L ++DN++ + +KEK + ++ D L E ++ +A G E +C +L+ Q
Sbjct: 1206 LGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAE-------AISKAKGNLEKMCRSLEDQ 1258
Query: 139 MKYLEQQQDETK---------------QAQEEARRLRSKMKTMEQIELLLQSQRPEVEEM 183
+ L+ +++E + +A E +R+L K + Q+ Q+ ++EE+
Sbjct: 1259 VSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEEL 1318
Query: 184 IRDMGVGQSAVEQLAVY-------CVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
+ A LA C L+++YE +E + K ++ R+K
Sbjct: 1319 KHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1378
Query: 237 QT----VYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQET 277
+T EL++AK +L AQ+ LQ A++ + ++ K L++T
Sbjct: 1379 ETDAIQRTEELEEAKKKL--AQR-LQEAEEHVEAVNAKCASLEKT 1420
Score = 53.1 bits (126), Expect = 5e-07
Identities = 56/252 (22%), Positives = 114/252 (45%), Gaps = 24/252 (9%)
Query: 61 KLFFDL-AQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVV 119
+L DL AQ +A +LD A +SQ + K+ S I+ L+ LEE
Sbjct: 1271 RLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKN 1330
Query: 120 SLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPE 179
+L AL + C L++Q + ++ + E ++A +A ++ +T + + + +++ E
Sbjct: 1331 ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 1390
Query: 180 --VEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLK----------EARKASGEVADKLRK 227
+++ + + + VE + C SL+K + L+ E A+ DK ++
Sbjct: 1391 EAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQR 1450
Query: 228 DLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIM--------SLKKKLTMLQETLN 279
+ S+ + Y E + EL+++QK+ +S E+ SL + T+ +E N
Sbjct: 1451 NFDKVLSEWKQKYEE---TQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKN 1507
Query: 280 LPPVASETVDRL 291
L S+ +++
Sbjct: 1508 LQQEISDLTEQI 1519
Score = 47.4 bits (111), Expect = 3e-05
Identities = 47/227 (20%), Positives = 99/227 (43%), Gaps = 41/227 (18%)
Query: 82 ELDNVRAQLSQKDKEK-------RDSQVIIDTLRDTLEERNATVVSLQQALGKAEMLCST 134
+++ ++ QL ++ K K + S+ D LR+ EE LQ+AL KA
Sbjct: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS--EV 1371
Query: 135 LKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQ-----------IELLLQSQRPEVEEM 183
+ + KY T++ +E ++L +++ E+ +E Q + EVE++
Sbjct: 1372 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDL 1431
Query: 184 IRDMGVGQSAVEQLAVYCVSL--------------KKEYENLKEARKASGEVADKLRKDL 229
+ D VE+ C +L K++YE + +AS + + L +L
Sbjct: 1432 MLD-------VERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTEL 1484
Query: 230 FSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQE 276
F ++ + +L+ + E K+ Q+++ ++I K++ L++
Sbjct: 1485 FKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531
Score = 43.9 bits (102), Expect = 3e-04
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 27/222 (12%)
Query: 61 KLFFDLAQEEENVLDAEFLKNELDNV----RAQLSQKDKEKRDSQVIIDTLRDTLEERNA 116
KL DL +E+ +D E K +LD ++S + D Q + L+ ++E A
Sbjct: 1057 KLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQA 1116
Query: 117 TVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQ 176
+ L + + + +KQ L ++ +E + EEA T Q+E L + +
Sbjct: 1117 RIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG-----ATSAQVE-LNKKR 1170
Query: 177 RPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKL 236
E +++ RD+ ++ ++ A+ KK +++ E GE D L
Sbjct: 1171 EAEFQKLRRDL--EEATLQHEAMVAALRKKHADSMAEL----GEQID-----------NL 1213
Query: 237 QTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
Q V +L++ K ELK DL S + I K L + +L
Sbjct: 1214 QRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSL 1255
Score = 43.5 bits (101), Expect = 4e-04
Identities = 52/245 (21%), Positives = 100/245 (40%), Gaps = 17/245 (6%)
Query: 60 NKLFFDLAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVV 119
N L + E +++ DAE +L + QL K KE + + EE NA +
Sbjct: 888 NDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKE-------VTERAEEEEEINAELT 940
Query: 120 SLQQALGKAEMLCSTLKKQMKYLE----QQQDETKQAQEEARRLRSKMKTMEQIELLLQS 175
+ ++ K E CS LKK + LE + + E + + + L +M +++ L
Sbjct: 941 AKKR---KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSK 997
Query: 176 QRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSK 235
++ ++E + A E K + E + + S E KLR DL ++ K
Sbjct: 998 EKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRK 1057
Query: 236 LQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQETLNLPPVASETVDRLVLES 295
L+ +L A+ + D Q D+++ + +++ L + + + + E
Sbjct: 1058 LE---GDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKEL 1114
Query: 296 PAPVE 300
A +E
Sbjct: 1115 QARIE 1119
Score = 40.0 bits (92), Expect = 0.005
Identities = 36/151 (23%), Positives = 75/151 (49%), Gaps = 15/151 (9%)
Query: 136 KKQMKYLEQQQDETKQ--AQEEARR--LRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQ 191
+K+M ++++ +TK A+ EA+R L KM T+ + + LQ Q + + D +
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD---AE 905
Query: 192 SAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSEL----DQAK 247
EQL + L+ + + + E E +++ +L + + KL+ SEL D +
Sbjct: 906 ERCEQLIKNKIQLEAKIKEVTER----AEEEEEINAELTAKKRKLEDECSELKKDIDDLE 961
Query: 248 LELKSAQKDLQSADKEIMSLKKKLTMLQETL 278
L L +K+ + + ++ +L +++ L ET+
Sbjct: 962 LTLAKVEKEKHATENKVKNLTEEMAGLDETI 992
Score = 38.1 bits (87), Expect = 0.017
Identities = 46/232 (19%), Positives = 99/232 (42%), Gaps = 16/232 (6%)
Query: 70 EENVLDAEFLKNELDNVRAQL-SQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKA 128
E+ +LDA L L + K K + D + + + ++E ++A+ A
Sbjct: 1706 EQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDA 1765
Query: 129 EMLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELL-LQSQRPEVEEMIRDM 187
M+ LKK+ + K ++ + L+ ++ EQ+ L + Q ++E +R++
Sbjct: 1766 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVREL 1825
Query: 188 GVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAK 247
G+ EQ K+ E +K RK V + L R + + +D+ +
Sbjct: 1826 -EGEVENEQ--------KRNAEAVKGLRKHERRVKE-LTYQTEEDRKNVLRLQDLVDKLQ 1875
Query: 248 LELKSAQKDLQSADKE----IMSLKKKLTMLQETLNLPPVASETVDRLVLES 295
++KS ++ + A+++ + +K L+E +A V++L ++S
Sbjct: 1876 AKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKS 1927
Score = 37.0 bits (84), Expect = 0.039
Identities = 46/236 (19%), Positives = 104/236 (44%), Gaps = 18/236 (7%)
Query: 44 RTCPQCRIQVGKRTIINKLFFDLAQE-EENVLDAEFLKNELDNVRAQLSQKDKEKRDSQV 102
R+ C K+ +K+ + Q+ EE + E + E ++ +L + +S
Sbjct: 1437 RSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLD 1496
Query: 103 IIDTLRDTLEERNATVVSLQQALGKAEMLCSTLKKQMKYLEQQQDETKQAQEEAR-RLRS 161
++TLR + + L + + + L+K K +EQ++ E + A EEA L
Sbjct: 1497 QLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEH 1556
Query: 162 KMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEV 221
+ + +I+L L + EV+ I + ++Q LK+ + + E +++ +
Sbjct: 1557 EEGKILRIQLELNQVKSEVDRKIAEK---DEEIDQ-------LKRNHTRVVETMQSTLDA 1606
Query: 222 ADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTMLQET 277
+ R D + K++ +L++ +++L A + A + + + + +L+ET
Sbjct: 1607 EIRSRNDALRVKKKME---GDLNEMEIQLNHANR---LAAESLRNYRNTQGILKET 1656
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,281,264
Number of Sequences: 37866
Number of extensions: 807029
Number of successful extensions: 7977
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 233
Number of HSP's successfully gapped in prelim test: 858
Number of HSP's that attempted gapping in prelim test: 4435
Number of HSP's gapped (non-prelim): 3076
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.