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Search of human proteins with 40807357
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
(643 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 1308 0.0
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 819 0.0
gi|62865631 solute carrier family 27 (fatty acid transporter), m... 422 e-118
gi|13325055 solute carrier family 27 (fatty acid transporter), m... 422 e-118
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 404 e-112
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 400 e-111
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 372 e-103
gi|227499621 solute carrier family 27 (fatty acid transporter), ... 302 5e-82
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 86 1e-16
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 86 1e-16
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 77 4e-14
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 77 4e-14
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 77 6e-14
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 73 7e-13
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 71 4e-12
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 71 4e-12
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 71 4e-12
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 70 8e-12
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 69 1e-11
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 69 1e-11
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 61 4e-09
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 61 4e-09
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 59 2e-08
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom... 56 9e-08
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 43 8e-04
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 43 8e-04
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 43 8e-04
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 43 8e-04
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 42 0.002
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor... 39 0.019
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 1308 bits (3384), Expect = 0.0
Identities = 643/643 (100%), Positives = 643/643 (100%)
Query: 1 MLLGASLVGVLLFSKLVLKLPWTQVGFSLLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLL 60
MLLGASLVGVLLFSKLVLKLPWTQVGFSLLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLL
Sbjct: 1 MLLGASLVGVLLFSKLVLKLPWTQVGFSLLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLL 60
Query: 61 KVKAKVRQCLQERRTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQA 120
KVKAKVRQCLQERRTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQA
Sbjct: 61 KVKAKVRQCLQERRTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQA 120
Query: 121 RGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFG 180
RGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFG
Sbjct: 121 RGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFG 180
Query: 181 SEMASAICEVHASLDPSLSLFCSGSWEPGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDK 240
SEMASAICEVHASLDPSLSLFCSGSWEPGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDK
Sbjct: 181 SEMASAICEVHASLDPSLSLFCSGSWEPGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDK 240
Query: 241 LFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQ 300
LFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQ
Sbjct: 241 LFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQ 300
Query: 301 CLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQHQVRMALG 360
CLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQHQVRMALG
Sbjct: 301 CLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQHQVRMALG 360
Query: 361 NGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVR 420
NGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVR
Sbjct: 361 NGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVR 420
Query: 421 VNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKK 480
VNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKK
Sbjct: 421 VNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKK 480
Query: 481 GDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVE 540
GDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVE
Sbjct: 481 GDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVE 540
Query: 541 VPGTEGRAGMAAVASPTGNCDLERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTE 600
VPGTEGRAGMAAVASPTGNCDLERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTE
Sbjct: 541 VPGTEGRAGMAAVASPTGNCDLERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTE 600
Query: 601 LRKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAGEEKL 643
LRKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAGEEKL
Sbjct: 601 LRKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAGEEKL 643
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 819 bits (2116), Expect = 0.0
Identities = 398/638 (62%), Positives = 489/638 (76%), Gaps = 2/638 (0%)
Query: 4 GASLVGVLLFSKL-VLKLPWTQVGFSLLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLLKV 62
GA V+ + L +L LPWT + L +Y+GSGGWRF+R+ KT RRD+FG VL++V
Sbjct: 5 GAGAASVVSLALLWLLGLPWTWSAAAALGVYVGSGGWRFLRIVCKTARRDLFGLSVLIRV 64
Query: 63 KAKVRQCLQERRTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQARG 122
+ ++R+ + T+P +F + V+R P++ AL+ GT WTF QLD YS++VAN + G
Sbjct: 65 RLELRRHQRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLG 124
Query: 123 LASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFGSE 182
A GDV AIF+E R EFVGLWLG+AK G+EAAL+N NLRR+ L CL TS A+AL+FG E
Sbjct: 125 FAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGE 184
Query: 183 MASAICEVHASLDPSLSLFCSGSWEPGAVPPSTEHLDPLLKDAPKH-LPSCPDKGFTDKL 241
M +A+ EV L SL FCSG P + P T LDPLLK+A L P KG D+L
Sbjct: 185 MVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGMDDRL 244
Query: 242 FYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQC 301
FYIYTSGTTGLPKAAIVVHSRYYRMAA ++ +RM+ D++YDCLPLYHSAGNI+G+GQC
Sbjct: 245 FYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQC 304
Query: 302 LLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQHQVRMALGN 361
L++G+TVV+RKKFSASRFWDDCIKYNCT+VQYIGE+CRYLL QP REAE +H+VR+A+GN
Sbjct: 305 LIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRLAVGN 364
Query: 362 GLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRV 421
GLR +IW F+ RF + Q+ EFYGATECNCS+ N D +VG+CGFNSRIL VYPIRLV+V
Sbjct: 365 GLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIRLVKV 424
Query: 422 NEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKG 481
NEDTMEL+R G+CIPCQ GEPG LVG+I Q+DPLRRFDGY+++ A +KKIA VF KG
Sbjct: 425 NEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSVFSKG 484
Query: 482 DQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEV 541
D AYL+GDVLVMDELGY+YFRDR+GDTFRW+GENVSTTEVEG LSRLL DVAVYGV V
Sbjct: 485 DSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVAV 544
Query: 542 PGTEGRAGMAAVASPTGNCDLERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTEL 601
PG EG+AGMAAVA P D Q L+K L YARPIFLRLLP++ TGT+K QKT L
Sbjct: 545 PGVEGKAGMAAVADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQKTRL 604
Query: 602 RKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAG 639
++EGFDP D LF+LD ++G Y+PL++ Y+RI +G
Sbjct: 605 QREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSG 642
>gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 422 bits (1084), Expect = e-118
Identities = 249/618 (40%), Positives = 350/618 (56%), Gaps = 23/618 (3%)
Query: 29 LLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLLKVKAKVRQCLQERRTVPILFASTVRRHP 88
LLF Y W ++V VL+ ++ K + E TV F S +R P
Sbjct: 22 LLFPYFWDDFWFVLKV-------------VLIIIRLKKYEKRGELVTVLDKFLSHAKRQP 68
Query: 89 DKTALIFEGTDTHWTFRQLDEYSSSVAN-FLQARGLASGDVAAIFMENRNEFVGLWLGMA 147
K +I+EG +T++ +D+ SS VA+ FL L GD A+ M N +FV +W G+A
Sbjct: 69 RKPFIIYEGDI--YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLA 126
Query: 148 KLGVEAALINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWE 207
KLG A +NTN+R ++LL+C+ RALV G+++ + E+ SL ++S++
Sbjct: 127 KLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSV 186
Query: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267
P V E L D P YI+TSGTTGLPKAA++ + R +
Sbjct: 187 PQGVISLKEKLSTS-PDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGS 245
Query: 268 ALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYN 327
A V + F +DIVY LPLYHS+ I+GI C+ G T V++KKFSAS+FW DC KY+
Sbjct: 246 A-VLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYD 304
Query: 328 CTIVQYIGELCRYLLNQPPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGAT 387
T+ QYIGELCRYL Q RE E H+VR+A+GNG+R +W F RF +V E Y AT
Sbjct: 305 VTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAAT 364
Query: 388 ECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQL 447
E + S N+ ++GA G + + L++ + E +R G CI + GEPG L
Sbjct: 365 ESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424
Query: 448 VGRIIQKDPLRRFDGYLNQGANNK-KIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTG 506
+ R+ K+P F GY + K K+ DVFKKGD TGD++V D+ +LYF DRTG
Sbjct: 425 ISRVNAKNP---FFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTG 481
Query: 507 DTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAA-VASPTGNCDLERF 565
DTFRWKGENV+TTEV + L + + VYGV + G EGRAGMA+ + P + DLE+
Sbjct: 482 DTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKV 541
Query: 566 AQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRY 625
+ + LP YA P FLR+ ++ TGT+K K +L ++GF+P + +PL+++D K Y
Sbjct: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSY 601
Query: 626 VPLDQEAYSRIQAGEEKL 643
V L +E Y +I GE KL
Sbjct: 602 VLLTRELYDQIMLGEIKL 619
>gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 422 bits (1084), Expect = e-118
Identities = 249/618 (40%), Positives = 350/618 (56%), Gaps = 23/618 (3%)
Query: 29 LLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLLKVKAKVRQCLQERRTVPILFASTVRRHP 88
LLF Y W ++V VL+ ++ K + E TV F S +R P
Sbjct: 22 LLFPYFWDDFWFVLKV-------------VLIIIRLKKYEKRGELVTVLDKFLSHAKRQP 68
Query: 89 DKTALIFEGTDTHWTFRQLDEYSSSVAN-FLQARGLASGDVAAIFMENRNEFVGLWLGMA 147
K +I+EG +T++ +D+ SS VA+ FL L GD A+ M N +FV +W G+A
Sbjct: 69 RKPFIIYEGDI--YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLA 126
Query: 148 KLGVEAALINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWE 207
KLG A +NTN+R ++LL+C+ RALV G+++ + E+ SL ++S++
Sbjct: 127 KLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSV 186
Query: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267
P V E L D P YI+TSGTTGLPKAA++ + R +
Sbjct: 187 PQGVISLKEKLSTS-PDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGS 245
Query: 268 ALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYN 327
A V + F +DIVY LPLYHS+ I+GI C+ G T V++KKFSAS+FW DC KY+
Sbjct: 246 A-VLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYD 304
Query: 328 CTIVQYIGELCRYLLNQPPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGAT 387
T+ QYIGELCRYL Q RE E H+VR+A+GNG+R +W F RF +V E Y AT
Sbjct: 305 VTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAAT 364
Query: 388 ECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQL 447
E + S N+ ++GA G + + L++ + E +R G CI + GEPG L
Sbjct: 365 ESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424
Query: 448 VGRIIQKDPLRRFDGYLNQGANNK-KIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTG 506
+ R+ K+P F GY + K K+ DVFKKGD TGD++V D+ +LYF DRTG
Sbjct: 425 ISRVNAKNP---FFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTG 481
Query: 507 DTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAA-VASPTGNCDLERF 565
DTFRWKGENV+TTEV + L + + VYGV + G EGRAGMA+ + P + DLE+
Sbjct: 482 DTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKV 541
Query: 566 AQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRY 625
+ + LP YA P FLR+ ++ TGT+K K +L ++GF+P + +PL+++D K Y
Sbjct: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSY 601
Query: 626 VPLDQEAYSRIQAGEEKL 643
V L +E Y +I GE KL
Sbjct: 602 VLLTRELYDQIMLGEIKL 619
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 404 bits (1038), Expect = e-112
Identities = 241/603 (39%), Positives = 342/603 (56%), Gaps = 20/603 (3%)
Query: 51 RDIFGGLVLLKVKAKVRQCLQER--RTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLD 108
+DI L + V +VR + R RT+ F R+ P K L+F D T+ Q+D
Sbjct: 28 QDIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFR--DETLTYAQVD 85
Query: 109 EYSSSVANFLQAR-GLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLH 167
S+ VA L GL GD A+ M N +V LWLG+ KLG A +N N+R +LLH
Sbjct: 86 RRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLH 145
Query: 168 CLTTSRARALVFGSEMASAICEVHASL---DPSLSLFCSGSWEPGAVPPSTEHLDPLLKD 224
C A+ L+ E+ +A+ E+ SL D S+ S G LD + +
Sbjct: 146 CFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGI----DSFLDKVDEV 201
Query: 225 APKHLPSC--PDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIV 282
+ + +P + F+ YIYTSGTTGLPKAA++ H R + L + ++ +D++
Sbjct: 202 STEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVS-GLKADDVI 260
Query: 283 YDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLL 342
Y LP YHSA ++GI C++ G T+ +R KFSAS+FWDDC KYN T++QYIGEL RYL
Sbjct: 261 YITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLC 320
Query: 343 NQPPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGA 402
N P + + H+VR+ALGNGLR +W F RF + EFY ATE N N+ +VGA
Sbjct: 321 NSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGA 380
Query: 403 CGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDG 462
G + + + L++ + + E +R +G C+ GE G LV +I Q P F+G
Sbjct: 381 VGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTP---FNG 437
Query: 463 YLNQGA-NNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEV 521
Y A KK +DVFKKGD + +GD+L++D ++YF DR GDTFRWKGENV+TTEV
Sbjct: 438 YAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEV 497
Query: 522 EGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTGN-CDLERFAQVLEKELPLYARPI 580
T+ + + +V VYGV VP EGR GMA++ + D ++ Q + LP YARP
Sbjct: 498 ADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPR 557
Query: 581 FLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAGE 640
FLR+ + TGT+K +K L +EGF+PA++KD L++LD YVP+ ++ Y+ I A
Sbjct: 558 FLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKT 617
Query: 641 EKL 643
KL
Sbjct: 618 LKL 620
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 400 bits (1029), Expect = e-111
Identities = 234/533 (43%), Positives = 308/533 (57%), Gaps = 19/533 (3%)
Query: 120 ARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVF 179
A L+ G A+ + EF+ LW G+AK G+ A + T LRR LLHCL + ARALV
Sbjct: 208 AAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARALVL 267
Query: 180 GSEMASAI-CEVHASLDPSLSLFCSGSWEPGAVPPSTEHLDPLLK-----DAPKHLPSCP 233
E ++ ++ A L L+ +G PG P L + P +L S
Sbjct: 268 APEFLESLEPDLPALRAMGLHLWAAG---PGTHPAGISDLLAEVSAEVDGPVPGYLSS-- 322
Query: 234 DKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAG 293
+ TD YI+TSGTTGLPKAA + H + + Y + D++Y LPLYH +G
Sbjct: 323 PQSITDTCLYIFTSGTTGLPKAARISHLKILQCQGF-YQLCGVHQEDVIYLALPLYHMSG 381
Query: 294 NIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQH 353
+++GI C+ G TVV++ KFSA +FW+DC ++ T+ QYIGELCRYL+NQPP +AE H
Sbjct: 382 SLLGIVGCMGIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQPPSKAERGH 441
Query: 354 QVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFV 413
+VR+A+G+GLR W F RF QV E YG TE N + N+ Q GA G S + +
Sbjct: 442 KVRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAVGRASWLYKHI 501
Query: 414 YPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDG--YLNQGANNK 471
+P L+R + T E IR P G C+ PGEPG LV + Q+ P + G L QG
Sbjct: 502 FPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLGYAGGPELAQG---- 557
Query: 472 KIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDM 531
K+ KDVF+ GD + TGD+LV D+ G+L F DRTGDTFRWKGENV+TTEV L +
Sbjct: 558 KLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFEALDFL 617
Query: 532 ADVAVYGVEVPGTEGRAGMAA-VASPTGNCDLERFAQVLEKELPLYARPIFLRLLPELHK 590
+V VYGV VPG EGRAGMAA V P DL + + + LP YARP FLRL L
Sbjct: 618 QEVNVYGVTVPGHEGRAGMAALVLRPPHALDLMQLYTHVSENLPPYARPRFLRLQESLAT 677
Query: 591 TGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAGEEKL 643
T T+K QK + EGFDP+ + DPL+ LD G Y+PL YS + AG ++
Sbjct: 678 TETFKQQKVRMANEGFDPSTLSDPLYVLDQAVGAYLPLTTARYSALLAGNLRI 730
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 372 bits (955), Expect = e-103
Identities = 237/601 (39%), Positives = 324/601 (53%), Gaps = 23/601 (3%)
Query: 59 LLKVKAKVRQCL--QERRTVPILFASTVRRHPDKTALIFEGTDT-HWTFRQLDEYSSSVA 115
+L + K+R CL Q T F R P + L++ G TF +LD + A
Sbjct: 97 ILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDARACQAA 156
Query: 116 NFLQAR-----GLASGDVAAIFMENRNEFVGL--WLGMAKLGVEAALINTNLRRDALLHC 168
L+A L +G+ A+ + L WLG+AKLG A IN + R L H
Sbjct: 157 WALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHS 216
Query: 169 LTTSRARALVFGSEMASAICEVHASLDP-SLSLFCSGSWEPGAVPPSTEHLDPLLKDAPK 227
+ +S AR LV ++ ++ E+ L ++ F P P L L AP
Sbjct: 217 VLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSP---TPGVGALGAALDAAPS 273
Query: 228 H-LPSCPDKGFT--DKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYD 284
H +P+ G T +IYTSGTTGLPK AI+ H R +M+ ++ +D+VY
Sbjct: 274 HPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLS-GATADDVVYT 332
Query: 285 CLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQ 344
LPLYH G +VGI CL G T V+ KFS S FWDDC ++ T++ Y+GEL RYL N
Sbjct: 333 VLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNI 392
Query: 345 PPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACG 404
P + + H VR+A+GNGLR +W F RF ++ E YG+TE N L N+ + GA G
Sbjct: 393 PQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALG 452
Query: 405 FNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYL 464
S +L + P LV+ + + E +R G CIP GEPG L+ +++ + P F GY
Sbjct: 453 KMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQP---FVGYR 509
Query: 465 N-QGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEG 523
+ + +K+ ++V + GD Y TGDVL MD G+LYFRDR GDTFRWKGENVST EVEG
Sbjct: 510 GPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEG 569
Query: 524 TLSRLLDMADVAVYGVEVPGTEGRAGMAAV-ASPTGNCDLERFAQVLEKELPLYARPIFL 582
LS++ + V VYGV VPG EG+ GMAAV +P D E+ Q + LP YA P F+
Sbjct: 570 VLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFI 629
Query: 583 RLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAGEEK 642
R+ + T T+K KT L +EGF+ IV DPLF LD + + PL E Y + G +
Sbjct: 630 RIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWR 689
Query: 643 L 643
L
Sbjct: 690 L 690
>gi|227499621 solute carrier family 27 (fatty acid transporter),
member 2 isoform 2 [Homo sapiens]
Length = 567
Score = 302 bits (774), Expect = 5e-82
Identities = 210/603 (34%), Positives = 304/603 (50%), Gaps = 73/603 (12%)
Query: 51 RDIFGGLVLLKVKAKVRQCLQER--RTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLD 108
+DI L + V +VR + R RT+ F R+ P K L+F D T+ Q+D
Sbjct: 28 QDIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFR--DETLTYAQVD 85
Query: 109 EYSSSVANFLQAR-GLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLH 167
S+ VA L GL GD A+ M N +V LWLG+ KLG A +N N+R +LLH
Sbjct: 86 RRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLH 145
Query: 168 CLTTSRARALVFGSEMASAICEVHASL---DPSLSLFCSGSWEPGAVPPSTEHLDPLLKD 224
C A+ L+ E+ +A+ E+ SL D S+ S G LD + +
Sbjct: 146 CFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGI----DSFLDKVDEV 201
Query: 225 APKHLPSC--PDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIV 282
+ + +P + F+ YIYTSGTTG A + + +++ +A ++
Sbjct: 202 STEPIPESWRSEVTFSTPALYIYTSGTTG---ATLALRTKF---SASQFW---------- 245
Query: 283 YDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLL 342
C + +TV+ QYIGEL RYL
Sbjct: 246 ----------------DDCRKYNVTVI----------------------QYIGELLRYLC 267
Query: 343 NQPPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGA 402
N P + + H+VR+ALGNGLR +W F RF + EFY ATE N N+ +VGA
Sbjct: 268 NSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGA 327
Query: 403 CGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDG 462
G + + + L++ + + E +R +G C+ GE G LV +I Q P F+G
Sbjct: 328 VGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTP---FNG 384
Query: 463 YLNQGA-NNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEV 521
Y A KK +DVFKKGD + +GD+L++D ++YF DR GDTFRWKGENV+TTEV
Sbjct: 385 YAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEV 444
Query: 522 EGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTGN-CDLERFAQVLEKELPLYARPI 580
T+ + + +V VYGV VP EGR GMA++ + D ++ Q + LP YARP
Sbjct: 445 ADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPR 504
Query: 581 FLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAGE 640
FLR+ + TGT+K +K L +EGF+PA++KD L++LD YVP+ ++ Y+ I A
Sbjct: 505 FLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKT 564
Query: 641 EKL 643
KL
Sbjct: 565 LKL 567
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 85.5 bits (210), Expect = 1e-16
Identities = 136/528 (25%), Positives = 211/528 (39%), Gaps = 59/528 (11%)
Query: 96 EGTDTHWTFRQLDEYSSSVANFLQ-ARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154
+G + W FR+L E S AN L A GL GD A+ + E+ + LG + G+
Sbjct: 75 KGKELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFM 134
Query: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSL-------FCSGSWE 207
++ +L+ L S+A+A+V G E+ + V AS PSL + C G W
Sbjct: 135 PGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTV-ASECPSLRIKLLVSEKSCDG-WL 192
Query: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267
+ LL +A C + G + +TSGT+GLPK A +S A
Sbjct: 193 ---------NFKKLLNEAST-THHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKA 242
Query: 268 ALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMT------VVIRKKFSASRFWD 321
+ ++ +DI++ G I+ I LL T V + KF
Sbjct: 243 KMDAGWTGLQASDIMWTI----SDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILK 298
Query: 322 DCIKYNCTIVQYIGELCRYLLNQPPREAENQH-QVRMALGNGLRQSIWTNFSSRFHIPQV 380
Y + + R LL Q + H Q +A G L N+ ++ + +
Sbjct: 299 TLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL-DI 357
Query: 381 AEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQ 440
EFYG TE + + G+ S Y ++++ G +P
Sbjct: 358 REFYGQTETGLTCMVSKTMKIKPGYMGTAAS-CYDVQVI-----------DDKGNVLP-- 403
Query: 441 PGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLY 500
PG G + R+ P+ F GY+ N K A ++ +GD +L GD + DE GY
Sbjct: 404 PGTEGDIGIRVKPIRPIGIFSGYVE---NPDKTAANI--RGD-FWLLGDRGIKDEDGYFQ 457
Query: 501 FRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAV--ASPTG 558
F R D G + +EVE L + + + AV P G A V AS
Sbjct: 458 FMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDP-VRGEVVKAFVILASQFL 516
Query: 559 NCDLERFAQVLEKELPL----YARPIFLRLLPELHKTGTYKFQKTELR 602
+ D E+ + L++ + Y P + + L KT T K Q+T+LR
Sbjct: 517 SHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 564
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 85.5 bits (210), Expect = 1e-16
Identities = 136/528 (25%), Positives = 211/528 (39%), Gaps = 59/528 (11%)
Query: 96 EGTDTHWTFRQLDEYSSSVANFLQ-ARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154
+G + W FR+L E S AN L A GL GD A+ + E+ + LG + G+
Sbjct: 75 KGKELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFM 134
Query: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSL-------FCSGSWE 207
++ +L+ L S+A+A+V G E+ + V AS PSL + C G W
Sbjct: 135 PGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTV-ASECPSLRIKLLVSEKSCDG-WL 192
Query: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267
+ LL +A C + G + +TSGT+GLPK A +S A
Sbjct: 193 ---------NFKKLLNEAST-THHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKA 242
Query: 268 ALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMT------VVIRKKFSASRFWD 321
+ ++ +DI++ G I+ I LL T V + KF
Sbjct: 243 KMDAGWTGLQASDIMWTI----SDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILK 298
Query: 322 DCIKYNCTIVQYIGELCRYLLNQPPREAENQH-QVRMALGNGLRQSIWTNFSSRFHIPQV 380
Y + + R LL Q + H Q +A G L N+ ++ + +
Sbjct: 299 TLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL-DI 357
Query: 381 AEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQ 440
EFYG TE + + G+ S Y ++++ G +P
Sbjct: 358 REFYGQTETGLTCMVSKTMKIKPGYMGTAAS-CYDVQVI-----------DDKGNVLP-- 403
Query: 441 PGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLY 500
PG G + R+ P+ F GY+ N K A ++ +GD +L GD + DE GY
Sbjct: 404 PGTEGDIGIRVKPIRPIGIFSGYVE---NPDKTAANI--RGD-FWLLGDRGIKDEDGYFQ 457
Query: 501 FRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAV--ASPTG 558
F R D G + +EVE L + + + AV P G A V AS
Sbjct: 458 FMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDP-VRGEVVKAFVILASQFL 516
Query: 559 NCDLERFAQVLEKELPL----YARPIFLRLLPELHKTGTYKFQKTELR 602
+ D E+ + L++ + Y P + + L KT T K Q+T+LR
Sbjct: 517 SHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 564
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 77.4 bits (189), Expect = 4e-14
Identities = 129/527 (24%), Positives = 207/527 (39%), Gaps = 57/527 (10%)
Query: 96 EGTDTHWTFRQLDEYSSSVANFLQ-ARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154
+G + W FR+L E S AN L A GL GD A+ + E+ + LG + G+
Sbjct: 75 KGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFM 134
Query: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSL-------FCSGSWE 207
++ +L+ L S+A+A+V G E+ + V AS PSL + C G W
Sbjct: 135 PGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTV-ASECPSLRIKLLVSEKSCDG-WL 192
Query: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267
+ LL +A C + G + +TSGT+GLPK A +S A
Sbjct: 193 ---------NFKKLLNEAST-THHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKA 242
Query: 268 ALVYYGFRMRPNDIVYD------CLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWD 321
+ ++ +DI++ L + S +G C V + KF
Sbjct: 243 KMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTF----VHLLPKFDPLVILK 298
Query: 322 DCIKYNCTIVQYIGELCRYLLNQPPREAENQH-QVRMALGNGLRQSIWTNFSSRFHIPQV 380
Y + + R LL Q + H Q + +G L N+ ++ + +
Sbjct: 299 TLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGL-DI 357
Query: 381 AEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQ 440
E YG TE + + G+ S Y ++++ G +P
Sbjct: 358 RESYGQTETGLTCMVSKTMKIKPGYMGTAAS-CYDVQII-----------DDKGNVLP-- 403
Query: 441 PGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLY 500
PG G + R+ P+ F GY++ N K A ++ +GD +L GD + DE GY
Sbjct: 404 PGTEGDIGIRVKPIRPIGIFSGYVD---NPDKTAANI--RGD-FWLLGDRGIKDEDGYFQ 457
Query: 501 FRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVP-GTEGRAGMAAVASPTGN 559
F R D G + +EVE L + + AV P E +AS +
Sbjct: 458 FMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLS 517
Query: 560 CDLERFAQVLEKELPL----YARPIFLRLLPELHKTGTYKFQKTELR 602
D E+ + L++ + Y P + + L KT T K Q+ +LR
Sbjct: 518 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLR 564
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 77.4 bits (189), Expect = 4e-14
Identities = 121/563 (21%), Positives = 223/563 (39%), Gaps = 58/563 (10%)
Query: 74 RTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQARGLASGDVAAIFM 133
+TV +T +R P++ AL+ D TF QL E A+ L + GL GD ++
Sbjct: 72 KTVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWG 131
Query: 134 ENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFGSEM-ASAICEVHA 192
N +V + L A+ G+ +N + L + L +ALVF + V
Sbjct: 132 PNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLK 191
Query: 193 SLDPSLSLFCSGSWEPGAVP------------PSTEHLDPLLK--DAPKHLPSCP-DKGF 237
+ P + G+ + +P P T LD ++ +HL ++ F
Sbjct: 192 QICPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQF 251
Query: 238 T---DKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCL------PL 288
D + +TSGTTG PK A + H + ++ G R++ ++ + L PL
Sbjct: 252 LSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNIL--GERLKLHEKTPEQLRMILPNPL 309
Query: 289 YHSAGNIVGIGQCLLHGMTVVIRKK-FSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPR 347
YH G++ G CL++G T+++ F+ + + + T + + +LNQP
Sbjct: 310 YHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDF 369
Query: 348 EAENQHQV--RMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECN-CSLGNF--DSQVGA 402
+ + + + G+ + ++ ++ + YG TE + + +F D+
Sbjct: 370 SSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQK 429
Query: 403 CGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDG 462
RI+ R++ + T+ + P +CI R +
Sbjct: 430 AESVGRIMPHT-EARIMNMEAGTLAKLNTPGELCI--------------------RGYCV 468
Query: 463 YLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVE 522
L +K + V + D+ Y TGDV M+E G+ R+ D GEN+ E+E
Sbjct: 469 MLGYWGEPQKTEEAVDQ--DKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELE 526
Query: 523 GTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTG-NCDLERFAQVLEKELPLYARPIF 581
+ +V V GV+ G A + G +E + ++ + P +
Sbjct: 527 DFFHTHPKVQEVQVVGVK-DDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPKY 585
Query: 582 LRLLPELHKTGTYKFQKTELRKE 604
+ + T + K QK +LR++
Sbjct: 586 IVFVTNYPLTISGKIQKFKLREQ 608
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 76.6 bits (187), Expect = 6e-14
Identities = 122/527 (23%), Positives = 211/527 (40%), Gaps = 52/527 (9%)
Query: 96 EGTDTHWTFRQLDEYSSSVANFL-QARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154
+G + W+FR+L S AN L + GL GD A+ + E+ + + + G+
Sbjct: 83 KGDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFM 142
Query: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWEPGAVPPS 214
L +L+ L S+A+ +V E+A A+ S+ L C V P
Sbjct: 143 PGTIQLTAKDILYRLRASKAKCIVASEEVAPAV--------ESIVLECPDLKTKLLVSPQ 194
Query: 215 TEH----LDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALV 270
+ + L + A + SC + G + + +TSGTTG PK A HS+
Sbjct: 195 SWNGWLSFQELFQFASEE-HSCVETGSQEPMTIYFTSGTTGFPKMA--QHSQSSLGIGFT 251
Query: 271 Y---YGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRK--KFSASRFWDDCIK 325
Y ++ +DI+++ I + L G V + + +F F D
Sbjct: 252 LCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTT 311
Query: 326 YNCTIVQYIGELCRYLLNQPPREAENQHQVRMALGNG--LRQSIWTNFSSRFHIPQVAEF 383
Y T + + R L+ + + + + +R L G L + + + + ++ E
Sbjct: 312 YPITTLCSPPTVYRMLVQKDLKRYKFK-SLRHCLTGGEPLNPEVLEQWRVQTGL-ELYEG 369
Query: 384 YGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGE 443
YG TE N Q G + + Y ++++ N + + PG+
Sbjct: 370 YGQTEVGMICANQKGQEIKPGSMGKGM-LPYDVQIIDENGNVLP-------------PGK 415
Query: 444 PGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRD 503
G++ R+ P F Y++ N +K A + +GD Y+TGD VMD GY +F
Sbjct: 416 EGEIALRLKPTRPFCFFSKYVD---NPQKTAATI--RGD-FYVTGDRGVMDSDGYFWFVG 469
Query: 504 RTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGV--EVPGTEGRAGMAAVASPTGNCD 561
R D G + EVE L + + AV ++ G +A +A+P + +
Sbjct: 470 RADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKA-FVVLAAPFKSYN 528
Query: 562 LERFAQVLE----KELPLYARPIFLRLLPELHKTGTYKFQKTELRKE 604
E+ L+ K Y P + + EL KT T K ++ LR +
Sbjct: 529 PEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQ 575
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 73.2 bits (178), Expect = 7e-13
Identities = 109/524 (20%), Positives = 199/524 (37%), Gaps = 48/524 (9%)
Query: 97 GTDTHWTFRQLDEYSSSVANFL-QARGLASGDVAAIFMENRNEFVGLWLG-MAKLGVEAA 154
G + W+F +L S AN L +A L GD + + E+ WL +A L
Sbjct: 90 GEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEW---WLANVACLRTGTV 146
Query: 155 LI--NTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWEPGAVP 212
LI T L + +L+ L +S+A ++ +A A+ V + C V
Sbjct: 147 LIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAVASK--------CENLHSKLIVS 198
Query: 213 PSTEHLDPLLKDAPKHLP---SCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRY-YRMAA 268
++ LK+ KH +C + + +TSGT+G PK HS + ++
Sbjct: 199 ENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSV 258
Query: 269 LVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRK--KFSASRFWDDCIKY 326
+ + P+D++++ + + + G V +F + KY
Sbjct: 259 NGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKY 318
Query: 327 NCTIVQYIGELCRYLLNQPPREAENQHQVR-MALGNGLRQSIWTNFSSRFHIPQVAEFYG 385
T+ + R L+ + + ++ G + + + ++ + + E YG
Sbjct: 319 PITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGL-DIYEGYG 377
Query: 386 ATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPG 445
TE GNF G + S + +++V VN + + PG+ G
Sbjct: 378 QTETVLICGNFKGMKIKPGSMGKP-SPAFDVKIVDVNGNVLP-------------PGQEG 423
Query: 446 QLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRT 505
+ +++ P F Y++ + + F Y+TGD MD+ GY +F R
Sbjct: 424 DIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNF------YITGDRGYMDKDGYFWFVARA 477
Query: 506 GDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTGNCD---- 561
D G + EVE L+ +A+ AV P V +P
Sbjct: 478 DDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQ 537
Query: 562 -LERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKE 604
++ + ++K Y P + + EL KT + K ++ ELRK+
Sbjct: 538 LIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKK 581
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 70.9 bits (172), Expect = 4e-12
Identities = 133/533 (24%), Positives = 202/533 (37%), Gaps = 75/533 (14%)
Query: 96 EGTDTHWTFRQLDEYSSSVANFLQ-ARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154
+G + W FR+L E S AN L A GL GD A+ + E+ + LG + G+
Sbjct: 75 KGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFM 134
Query: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSL-------FCSGSWE 207
++ +L+ L S+A+A+V G E+ + V AS PSL + C G W
Sbjct: 135 PGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTV-ASECPSLRIKLLVSEKSCDG-WL 192
Query: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267
+ LL +A C + G + +TSGT+GLPK A +S A
Sbjct: 193 ---------NFKKLLNEAST-THHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKA 242
Query: 268 ALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMT------VVIRKKFSASRFWD 321
+ ++ +DI++ G I+ I LL T V + KF
Sbjct: 243 KMDAGWTGLQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILK 298
Query: 322 DCIKYNCTIVQYIGELCRYLLNQPPREAENQH-QVRMALGNGLRQSIWTNFSSRFHIPQV 380
Y + + R LL Q + H Q +A G L N+ ++ + +
Sbjct: 299 TLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL-DI 357
Query: 381 AEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQ 440
EFYG TE L + TM++ G G C
Sbjct: 358 REFYGQTETG---------------------------LTCMVSKTMKIKPGYMGTAASCY 390
Query: 441 PGEPGQLVGRIIQKDPLRRFDG-----YLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDE 495
+ V + L F G + N K A ++ +GD +L GD + DE
Sbjct: 391 DVQVIAFVHGSPRAGDL-GFAGTMTLSFCGHQENPDKTAANI--RGD-FWLLGDRGIKDE 446
Query: 496 LGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAV-- 553
GY F R D G + +EVE L + + + AV P G A V
Sbjct: 447 DGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDP-VRGEVVKAFVIL 505
Query: 554 ASPTGNCDLERFAQVLEKELPL----YARPIFLRLLPELHKTGTYKFQKTELR 602
AS + D E+ + L++ + Y P + + L KT T K Q+T+LR
Sbjct: 506 ASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 70.9 bits (172), Expect = 4e-12
Identities = 133/533 (24%), Positives = 202/533 (37%), Gaps = 75/533 (14%)
Query: 96 EGTDTHWTFRQLDEYSSSVANFLQ-ARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154
+G + W FR+L E S AN L A GL GD A+ + E+ + LG + G+
Sbjct: 75 KGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFM 134
Query: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSL-------FCSGSWE 207
++ +L+ L S+A+A+V G E+ + V AS PSL + C G W
Sbjct: 135 PGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTV-ASECPSLRIKLLVSEKSCDG-WL 192
Query: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267
+ LL +A C + G + +TSGT+GLPK A +S A
Sbjct: 193 ---------NFKKLLNEAST-THHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKA 242
Query: 268 ALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMT------VVIRKKFSASRFWD 321
+ ++ +DI++ G I+ I LL T V + KF
Sbjct: 243 KMDAGWTGLQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILK 298
Query: 322 DCIKYNCTIVQYIGELCRYLLNQPPREAENQH-QVRMALGNGLRQSIWTNFSSRFHIPQV 380
Y + + R LL Q + H Q +A G L N+ ++ + +
Sbjct: 299 TLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL-DI 357
Query: 381 AEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQ 440
EFYG TE L + TM++ G G C
Sbjct: 358 REFYGQTETG---------------------------LTCMVSKTMKIKPGYMGTAASCY 390
Query: 441 PGEPGQLVGRIIQKDPLRRFDG-----YLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDE 495
+ V + L F G + N K A ++ +GD +L GD + DE
Sbjct: 391 DVQVIAFVHGSPRAGDL-GFAGTMTLSFCGHQENPDKTAANI--RGD-FWLLGDRGIKDE 446
Query: 496 LGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAV-- 553
GY F R D G + +EVE L + + + AV P G A V
Sbjct: 447 DGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDP-VRGEVVKAFVIL 505
Query: 554 ASPTGNCDLERFAQVLEKELPL----YARPIFLRLLPELHKTGTYKFQKTELR 602
AS + D E+ + L++ + Y P + + L KT T K Q+T+LR
Sbjct: 506 ASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 70.9 bits (172), Expect = 4e-12
Identities = 130/528 (24%), Positives = 198/528 (37%), Gaps = 54/528 (10%)
Query: 96 EGTDTHWTFRQLDEYSSSVAN-FLQARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154
+G + W+FR++ + + VAN F Q GL GD A+ + E+ + +G + G+
Sbjct: 80 QGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFI 139
Query: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLS--LFCSGSWEPGAVP 212
L+ +L+ L S+A+ +V +AS + + AS PSL L S G +
Sbjct: 140 PATILLKAKDILYRLQLSKAKGIVTIDALASEVDSI-ASQCPSLKTKLLVSDHSREGWLD 198
Query: 213 PSTEHLDPLLKDA-PKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVY 271
L+K A P+H +C D + +TSGTTG PK A H + +
Sbjct: 199 -----FRSLVKSASPEH--TCVKSKTLDPMVIFFTSGTTGFPKMAKHSHGLALQPSFPGS 251
Query: 272 YGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLH----GMTVVIR--KKFSASRFWDDCIK 325
R V CL +G IV L+ G TV I +F +K
Sbjct: 252 RKLRSLKTSDVSWCL---SDSGWIVATIWTLVEPWTAGCTVFIHHLPQFDTKVIIQTLLK 308
Query: 326 YNCTIVQYIGELCRYLLNQPPREAENQHQVRMALGNGL----RQSIWTNFSSRFHIPQVA 381
Y + + R +L Q G + Q W + +
Sbjct: 309 YPINHFWGVSSIYRMILQQDFTSIRFPALEHCYTGGEVVLPKDQEEWKRRTGLL----LY 364
Query: 382 EFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQP 441
E YG +E + GF + P V+V +D G +P P
Sbjct: 365 ENYGQSETGLICATYWGMKIKPGFMGK----ATPPYDVQVIDD--------KGSILP--P 410
Query: 442 GEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYF 501
G + RI P+ F Y K+ F Y TGD MDE GY+ F
Sbjct: 411 NTEGNIGIRIKPVRPVSLFMCYEGDPEKTAKVECGDF------YNTGDRGKMDEEGYICF 464
Query: 502 RDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTG-NC 560
R+ D G + EVE L +A+ AV G P V +P +
Sbjct: 465 LGRSDDIINASGYRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQFLSH 524
Query: 561 DLERFAQVLEKELPL----YARPIFLRLLPELHKTGTYKFQKTELRKE 604
D ++ + L++ + Y P + + EL KT T K ++ ELRK+
Sbjct: 525 DKDQLTKELQQHVKSVTAPYKYPRKVEFVSELPKTITGKIERKELRKK 572
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 69.7 bits (169), Expect = 8e-12
Identities = 122/571 (21%), Positives = 202/571 (35%), Gaps = 76/571 (13%)
Query: 89 DKTALIFEGTD----THWTFRQLDEYSSSVANFLQARGLASGDVAAIFMENRNEFVGLWL 144
DK A +EG + T T+ QL +N L+ +G+ GD AI+M E V L
Sbjct: 119 DKVAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAML 178
Query: 145 GMAKLGVEAALINTNLRRDALLHCLTTSRARALVFGSEM--ASAICEVHASLDPSLSLFC 202
A++G +++ ++L + S L+ + + D +L C
Sbjct: 179 ACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQK-C 237
Query: 203 SGSWEPGAVPPSTEHLDPL---LKDAPKHLP----SCPDKGFT----------------- 238
P +HL + D+ P SCPD +
Sbjct: 238 QEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQISWNQGIDLWWHELMQEAG 297
Query: 239 -----------DKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVY-YGFRMRPNDIVYDCL 286
D LF +YTSG+TG PK + Y A + Y F D+ +
Sbjct: 298 DECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTA 357
Query: 287 PLYHSAGNIVGIGQCLLHGMTVVIRKKF----SASRFWDDCIKYNCTIVQYIGELCRYLL 342
+ G+ L +G T V+ + +R W KY T R L+
Sbjct: 358 DIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLM 417
Query: 343 ---NQP-PREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDS 398
++P + + QV +G + W + GA C + +
Sbjct: 418 KFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYH---------RVVGAQRCPIVDTFWQT 468
Query: 399 QVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLR 458
+ G +L+ + ++ T + G+ G ++ K P
Sbjct: 469 ETGG-----HMLTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQP-- 521
Query: 459 RFDGYLNQG-ANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVS 517
+ G + N+++ FKK Y+TGD D+ GY + R D G +S
Sbjct: 522 -WPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLS 580
Query: 518 TTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTGNCDLERFAQVLEKEL---- 573
T EVE L +A+ AV G P +G V G+ + + L+K++
Sbjct: 581 TAEVESALVEHEAVAEAAVVGHPHP-VKGECLYCFVTLCDGHTFSPKLTEELKKQIREKI 639
Query: 574 -PLYARPIFLRLLPELHKTGTYKFQKTELRK 603
P+ A P +++ P L KT + K + LRK
Sbjct: 640 GPI-ATPDYIQNAPGLPKTRSGKIMRRVLRK 669
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 69.3 bits (168), Expect = 1e-11
Identities = 68/258 (26%), Positives = 120/258 (46%), Gaps = 22/258 (8%)
Query: 84 VRRHPDKTALIFE----GTDTHWTFRQLDEYSSSVANFLQARGLASGDVAAIFMENRNEF 139
VR+ P+ ALI+E GT+ T+R+L E + +AN L+ G+ GD AI+M
Sbjct: 119 VRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLA 178
Query: 140 VGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFGSE--MASAICEVHASLDPS 197
V L A++G +I ++L + ++ + ++ ++ + E+ +D +
Sbjct: 179 VAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEA 238
Query: 198 LSLFCSGSWEPGAVPPSTEH------LD-PLLKDAPKHLPSCPDK--GFTDKLFYIYTSG 248
+ C + + V T++ LD PL ++ K P C + G D LF +YTSG
Sbjct: 239 VK-HCP-TVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSG 296
Query: 249 TTGLPKAAIVVHSRYYRMAALVY-YGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMT 307
+TG+PK + + Y AAL + F +P DI + G+ + L +G T
Sbjct: 297 STGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGAT 356
Query: 308 VVIRKKF----SASRFWD 321
V+ + +A R+W+
Sbjct: 357 SVLFESTPVYPNAGRYWE 374
Score = 38.5 bits (88), Expect = 0.019
Identities = 33/139 (23%), Positives = 57/139 (41%), Gaps = 5/139 (3%)
Query: 469 NNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRL 528
++++ FK Y TGD E GY R D G + T E+E ++
Sbjct: 513 DHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEIEDAIADH 572
Query: 529 LDMADVAVYGV--EVPGTEGRAGMAAVASPTGNCD--LERFAQVLEKELPLYARPIFLRL 584
+ + AV G ++ G E V G+ D ++ ++ ++ YA P + +
Sbjct: 573 PAVPESAVIGYPHDIKG-EAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPDEILV 631
Query: 585 LPELHKTGTYKFQKTELRK 603
+ L KT + K + LRK
Sbjct: 632 VKRLPKTRSGKVMRRLLRK 650
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 68.9 bits (167), Expect = 1e-11
Identities = 127/526 (24%), Positives = 209/526 (39%), Gaps = 53/526 (10%)
Query: 97 GTDTHWTFRQLDEYSSSVANFLQ-ARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAAL 155
G + W+F +L + S AN L A GL GD + + E+ + + + G
Sbjct: 85 GAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIP 144
Query: 156 INTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLS--LFCSGSWEPGAVPP 213
T L L + L SRA++++ +A + + A PSL L S S PG +
Sbjct: 145 GVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAISAEC-PSLQTKLLVSDSSRPGWL-- 201
Query: 214 STEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYG 273
+ LL++A +C D L +TSGTTG PK +V HS+ V G
Sbjct: 202 ---NFRELLREASTE-HNCMRTKSRDPLAIYFTSGTTGAPK--MVEHSQSSYGLGFVASG 255
Query: 274 FR---MRPNDIVYDCLPL--YHSAGNIVGI---GQCLLHGMTVVIRKKFSASRFWDDCIK 325
R + +DI ++ +A + G C+ V + A + K
Sbjct: 256 RRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIF----VHELPRVDAKVILNTLSK 311
Query: 326 YNCTIVQYIGELCRYLLNQPPREAENQHQVRMAL--GNGLRQSIWTNFSSRFHIPQVAEF 383
+ T + + + R L+ + + Q +R L G L + + + + ++ E
Sbjct: 312 FPITTLCCVPTIFRLLVQEDLTRYQFQ-SLRHCLTGGEALNPDVREKWKHQTGV-ELYEG 369
Query: 384 YGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGE 443
YG +E N G + S Y +++V +G +P PGE
Sbjct: 370 YGQSETVVICANPKGMKIKSGSMGKA-SPPYDVQIV-----------DDEGNVLP--PGE 415
Query: 444 PGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRD 503
G + RI P F+ YL+ N +K A ++GD Y+TGD MD+ GY +F
Sbjct: 416 EGNVAVRIRPTRPFCFFNCYLD---NPEKTAAS--EQGD-FYITGDRARMDKDGYFWFMG 469
Query: 504 RTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPT-GNCDL 562
R D + EVE L+ + + AV P V +P + D
Sbjct: 470 RNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDP 529
Query: 563 ERFAQVLEKELPL----YARPIFLRLLPELHKTGTYKFQKTELRKE 604
E + L++ + Y P + + EL KT + K Q+++LR +
Sbjct: 530 EALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQ 575
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 60.8 bits (146), Expect = 4e-09
Identities = 101/404 (25%), Positives = 155/404 (38%), Gaps = 40/404 (9%)
Query: 224 DAPKHLPSCPDKGFTDK-LFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIV 282
+ P +P P++G+ +K IYTSGTTG PK + H + + + + +D++
Sbjct: 180 EEPAEVP-VPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVI 238
Query: 283 YDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNC----------TIVQ 332
LPL+H G + + L G T V+ +FS + W+ + TI
Sbjct: 239 LHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYT 298
Query: 333 YIGELCRYLLNQPPRE----AENQHQVRMALGNGLRQSI-----WTNFSSRFHIPQVAEF 383
+ E QP + A + ++R+ + + W N + + E
Sbjct: 299 KLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGH----TLLER 354
Query: 384 YGATECNCSL-GNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPG 442
YG TE +L G + V G L V +R+V N R I +
Sbjct: 355 YGMTEIGMALSGPLTTAVRLPGSVGTPLPGV-QVRIVSENPQ-----REACSYTIHAEGD 408
Query: 443 EPGQLVGRIIQK---DPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYL 499
E G V ++ + L R + N + K F D + TGD +V + G
Sbjct: 409 ERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTL-DGWFKTGDTVVFKD-GQY 466
Query: 500 YFRDRTG-DTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTG 558
+ R RT D + G VS EVE L + DVAV GV T G+ A V G
Sbjct: 467 WIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVP-DMTWGQRVTAVVTLREG 525
Query: 559 NCDLER-FAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTEL 601
+ R + L YA P L L+ E+ + K K L
Sbjct: 526 HSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 60.8 bits (146), Expect = 4e-09
Identities = 101/404 (25%), Positives = 155/404 (38%), Gaps = 40/404 (9%)
Query: 224 DAPKHLPSCPDKGFTDK-LFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIV 282
+ P +P P++G+ +K IYTSGTTG PK + H + + + + +D++
Sbjct: 180 EEPAEVP-VPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVI 238
Query: 283 YDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNC----------TIVQ 332
LPL+H G + + L G T V+ +FS + W+ + TI
Sbjct: 239 LHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYT 298
Query: 333 YIGELCRYLLNQPPRE----AENQHQVRMALGNGLRQSI-----WTNFSSRFHIPQVAEF 383
+ E QP + A + ++R+ + + W N + + E
Sbjct: 299 KLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGH----TLLER 354
Query: 384 YGATECNCSL-GNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPG 442
YG TE +L G + V G L V +R+V N R I +
Sbjct: 355 YGMTEIGMALSGPLTTAVRLPGSVGTPLPGV-QVRIVSENPQ-----REACSYTIHAEGD 408
Query: 443 EPGQLVGRIIQK---DPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYL 499
E G V ++ + L R + N + K F D + TGD +V + G
Sbjct: 409 ERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTL-DGWFKTGDTVVFKD-GQY 466
Query: 500 YFRDRTG-DTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTG 558
+ R RT D + G VS EVE L + DVAV GV T G+ A V G
Sbjct: 467 WIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVP-DMTWGQRVTAVVTLREG 525
Query: 559 NCDLER-FAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTEL 601
+ R + L YA P L L+ E+ + K K L
Sbjct: 526 HSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 58.5 bits (140), Expect = 2e-08
Identities = 85/380 (22%), Positives = 141/380 (37%), Gaps = 34/380 (8%)
Query: 239 DKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVY-YGFRMRPNDIVYDCLPLYHSAGNIVG 297
D LF +YTSG+TG PK + Y A + Y F D+ + + G+
Sbjct: 322 DPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYV 381
Query: 298 IGQCLLHGMTVVIRKKF----SASRFWDDCIKYNCTIVQYIGELCRYLL---NQP-PREA 349
L +G T V+ + +R W KY T R L+ ++P + +
Sbjct: 382 TYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHS 441
Query: 350 ENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRI 409
QV +G + W + GA C + ++ G +
Sbjct: 442 RASLQVLGTVGEPINPEAWLWYH---------RVVGAQRCPIVDTFWQTETGG-----HM 487
Query: 410 LSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQG-A 468
L+ + ++ T + G+ G ++ K P + G +
Sbjct: 488 LTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQP---WPGIMRTVYG 544
Query: 469 NNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRL 528
N+++ FKK Y+TGD D+ GY + R D G +ST EVE L
Sbjct: 545 NHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEH 604
Query: 529 LDMADVAVYGVEVPGTEGRAGMAAVASPTGNCDLERFAQVLEKEL-----PLYARPIFLR 583
+A+ AV G P +G V G+ + + L+K++ P+ A P +++
Sbjct: 605 EAVAEAAVVGHPHP-VKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPI-ATPDYIQ 662
Query: 584 LLPELHKTGTYKFQKTELRK 603
P L KT + K + LRK
Sbjct: 663 NAPGLPKTRSGKIMRRVLRK 682
Score = 37.0 bits (84), Expect = 0.056
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 89 DKTALIFEGTD----THWTFRQLDEYSSSVANFLQARGLASGDVAAIFMENRNEFVGLWL 144
DK A +EG + T T+ QL +N L+ +G+ GD AI+M E V L
Sbjct: 119 DKVAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAML 178
Query: 145 GMAKLGVEAALINTNLRRDALLHCLTTSRARALV 178
A++G +++ ++L + S L+
Sbjct: 179 ACARIGALHSIVFAGFSSESLCERILDSSCSLLI 212
>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
sapiens]
Length = 686
Score = 56.2 bits (134), Expect = 9e-08
Identities = 110/499 (22%), Positives = 188/499 (37%), Gaps = 78/499 (15%)
Query: 89 DKTALIFEGTDTH----WTFRQLDEYSSSVANFLQARGLASGDVAAIFMENRNEFVGLWL 144
DK A+I++ T+ +T++++ E S +A L G+ GD I+M + + L
Sbjct: 127 DKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQAMYTML 186
Query: 145 GMAKLGVEAALINTNLRRDALLHCLTTSRARALV---FGSE---------MASAICEVHA 192
A++G +LI L + + + +V FG E + ++
Sbjct: 187 ACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQ 246
Query: 193 SLDPSLSLFCSGSWEPGAVPPSTE-HLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTG 251
+ ++ + E + P + D + A H C L+ +YTSGTTG
Sbjct: 247 HKPDKILIYNRPNMEAVPLAPGRDLDWDEEMAKAQSH--DCVPVLSEHPLYILYTSGTTG 304
Query: 252 LPKAAIVVHSRYYRMAALVYYG----FRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMT 307
LPK I Y A ++++ + ++P ++ + L G+ LLHG T
Sbjct: 305 LPKGVIRPTGGY---AVMLHWSMSSIYGLQPGEVWWAASDLGWVVGHSYICYGPLLHGNT 361
Query: 308 VVIRKKF-----SASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQH----QVRMA 358
V+ + A ++ ++ + R + Q P A + + +
Sbjct: 362 TVLYEGKPVGTPDAGAYFRVLAEHGVAALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTL 421
Query: 359 LGNGLRQSIWTNFSSR--FHIPQVAEFYGATE------CNC-SLGNFDS----QVGAC-- 403
G R + T S+ F +P V + + TE +C LGN + Q G
Sbjct: 422 FVAGERCDVETLEWSKNVFRVP-VLDHWWQTETGSPITASCVGLGNSKTPPPGQAGKSVP 480
Query: 404 GFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGY 463
G+N IL +D M+ ++ + +G I+ K PL +
Sbjct: 481 GYNVMIL------------DDNMQKLKA--------------RCLGNIVVKLPLPP-GAF 513
Query: 464 LNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEG 523
N + F+K Y T D MDE GYLY R D G +S +E
Sbjct: 514 SGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVINVAGHRISAGAIEE 573
Query: 524 TLSRLLDMADVAVYGVEVP 542
++ +AD AV G E P
Sbjct: 574 SILSHGTVADCAVVGKEDP 592
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 43.1 bits (100), Expect = 8e-04
Identities = 54/227 (23%), Positives = 88/227 (38%), Gaps = 51/227 (22%)
Query: 103 TFRQLDEYSSSVANFLQARGLASG--DVAAIFMENRNEFVGLWLGMAKLGVEAALINTNL 160
+++Q+ + + + + L +G S IF +NR E++ L + A + L
Sbjct: 107 SYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTL 166
Query: 161 RRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWEPGAVPPSTEHL-- 218
+A++H +V +++A IC+ P +L G+ E G P +
Sbjct: 167 GPEAIVH---------IVNKADIAMVICDT-----PQKALVLIGNVEKGFTPSLKVIILM 212
Query: 219 DPL-----------------LKDAP--------KHLPSCPDKGFTDKLFYIYTSGTTGLP 253
DP L DA K +P P+ D +TSGTTG P
Sbjct: 213 DPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPE----DLSVICFTSGTTGDP 268
Query: 254 KAAIVVHSRYYRMAA----LVYYGFRMRPNDIVYDCLPLYHSAGNIV 296
K A++ H AA V + + P+D+ LPL H IV
Sbjct: 269 KGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIV 315
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 43.1 bits (100), Expect = 8e-04
Identities = 54/227 (23%), Positives = 88/227 (38%), Gaps = 51/227 (22%)
Query: 103 TFRQLDEYSSSVANFLQARGLASG--DVAAIFMENRNEFVGLWLGMAKLGVEAALINTNL 160
+++Q+ + + + + L +G S IF +NR E++ L + A + L
Sbjct: 107 SYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTL 166
Query: 161 RRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWEPGAVPPSTEHL-- 218
+A++H +V +++A IC+ P +L G+ E G P +
Sbjct: 167 GPEAIVH---------IVNKADIAMVICDT-----PQKALVLIGNVEKGFTPSLKVIILM 212
Query: 219 DPL-----------------LKDAP--------KHLPSCPDKGFTDKLFYIYTSGTTGLP 253
DP L DA K +P P+ D +TSGTTG P
Sbjct: 213 DPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPE----DLSVICFTSGTTGDP 268
Query: 254 KAAIVVHSRYYRMAA----LVYYGFRMRPNDIVYDCLPLYHSAGNIV 296
K A++ H AA V + + P+D+ LPL H IV
Sbjct: 269 KGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIV 315
>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
a [Homo sapiens]
Length = 739
Score = 43.1 bits (100), Expect = 8e-04
Identities = 54/227 (23%), Positives = 88/227 (38%), Gaps = 51/227 (22%)
Query: 103 TFRQLDEYSSSVANFLQARGLASG--DVAAIFMENRNEFVGLWLGMAKLGVEAALINTNL 160
+++Q+ + + + + L +G S IF +NR E++ L + A + L
Sbjct: 163 SYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTL 222
Query: 161 RRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWEPGAVPPSTEHL-- 218
+A++H +V +++A IC+ P +L G+ E G P +
Sbjct: 223 GPEAIVH---------IVNKADIAMVICDT-----PQKALVLIGNVEKGFTPSLKVIILM 268
Query: 219 DPL-----------------LKDAP--------KHLPSCPDKGFTDKLFYIYTSGTTGLP 253
DP L DA K +P P+ D +TSGTTG P
Sbjct: 269 DPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPE----DLSVICFTSGTTGDP 324
Query: 254 KAAIVVHSRYYRMAA----LVYYGFRMRPNDIVYDCLPLYHSAGNIV 296
K A++ H AA V + + P+D+ LPL H IV
Sbjct: 325 KGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIV 371
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 43.1 bits (100), Expect = 8e-04
Identities = 46/196 (23%), Positives = 82/196 (41%), Gaps = 19/196 (9%)
Query: 97 GTDTHWTFRQLDEYSSSVANFL-QARGLASGDVAAIFMENRNEFVGLWLG-MAKLGVEAA 154
G + W+F +L S AN L +A L GD + + E+ WL +A L
Sbjct: 90 GEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEW---WLANVACLRTGTV 146
Query: 155 LI--NTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWEPGAVP 212
LI T L + +L+ L +S+A ++ +A A+ V + C V
Sbjct: 147 LIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAVASK--------CENLHSKLIVS 198
Query: 213 PSTEHLDPLLKDAPKHLP---SCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRY-YRMAA 268
++ LK+ KH +C + + +TSGT+G PK HS + ++
Sbjct: 199 ENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSV 258
Query: 269 LVYYGFRMRPNDIVYD 284
+ + P+D++++
Sbjct: 259 NGRFWLDLTPSDVMWN 274
>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
sapiens]
Length = 480
Score = 42.0 bits (97), Expect = 0.002
Identities = 86/431 (19%), Positives = 157/431 (36%), Gaps = 40/431 (9%)
Query: 96 EGTDTHWTFRQLDEYSSSVANFLQAR-GLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154
+G + W+F ++ + S A+ L L+ GD I + E + L +LG+
Sbjct: 80 KGEEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFV 139
Query: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSL--SLFCSGSWEPGAVP 212
+ L + + L S+A+ +V MA + S P+L L S G +
Sbjct: 140 PGSPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSA-VSDCPTLKTKLLVSDKSYDGWL- 197
Query: 213 PSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYY 272
L++ AP K D + +T GTTG PK +V +S+Y
Sbjct: 198 ----DFKKLIQVAPPKQTYMRTKS-QDPMAIFFTKGTTGAPK--MVEYSQYGLGMGFSQA 250
Query: 273 GFR---MRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVI--RKKFSASRFWDDCIKYN 327
R ++P D+++ + + ++ + G V + F + ++
Sbjct: 251 SRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFP 310
Query: 328 CTIVQYIGELCRYLLNQPPREAENQHQVR--MALGNGLRQSIWTNFSSRFHIPQVAEFYG 385
T + E+ + LL + ++ +A G + + ++ R + E YG
Sbjct: 311 ITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEGYG 369
Query: 386 ATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPG 445
TE G + L P +V++ ++ L+ PGE G
Sbjct: 370 QTE----TGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSNLL----------PPGEEG 415
Query: 446 QLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRT 505
+ RI P + ++ +G YLTGD +MDE GY ++ R
Sbjct: 416 NIAIRIKLNQPASLYCPHMVSWEEYAS------ARGHMLYLTGDRGIMDEDGYFWWSGRV 469
Query: 506 GDTFRWKGENV 516
D G+ +
Sbjct: 470 DDVANALGQRL 480
>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
[Homo sapiens]
Length = 670
Score = 38.5 bits (88), Expect = 0.019
Identities = 52/198 (26%), Positives = 81/198 (40%), Gaps = 20/198 (10%)
Query: 109 EYSSSVANF---LQARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDAL 165
E + V NF L A GL + AIF E R E++ K + L ++A+
Sbjct: 89 EVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAV 148
Query: 166 LHCLTTSRARALVFGSEMASAICEVHASLDPSL---------SLFCSGSWEPGAVPPSTE 216
+H L S A L+ E+ + + A LD S + G S +
Sbjct: 149 VHGLNESEASYLITSVELLESKLKT-ALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQ 207
Query: 217 HLDPLLKDAPKHLPSCPDKGF-TDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFR 275
++ L + P++L P + +D +YTSG+TG PK ++ HS +A + R
Sbjct: 208 SVEELGSN-PENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNL--IAGMTGQCER 264
Query: 276 ---MRPNDIVYDCLPLYH 290
+ P D LPL H
Sbjct: 265 IPGLGPKDTYIGYLPLAH 282
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,270,661
Number of Sequences: 37866
Number of extensions: 1088883
Number of successful extensions: 2458
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2366
Number of HSP's gapped (non-prelim): 61
length of query: 643
length of database: 18,247,518
effective HSP length: 109
effective length of query: 534
effective length of database: 14,120,124
effective search space: 7540146216
effective search space used: 7540146216
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.