BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens] (712 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens] 1463 0.0 gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens] 1266 0.0 gi|4557759 myeloperoxidase [Homo sapiens] 736 0.0 gi|4503595 eosinophil peroxidase [Homo sapiens] 727 0.0 gi|28558982 thyroid peroxidase isoform a [Homo sapiens] 540 e-153 gi|28558988 thyroid peroxidase isoform d [Homo sapiens] 540 e-153 gi|28558984 thyroid peroxidase isoform b [Homo sapiens] 452 e-127 gi|109150416 peroxidasin [Homo sapiens] 451 e-126 gi|126517478 peroxidasin homolog-like [Homo sapiens] 398 e-110 gi|28558990 thyroid peroxidase isoform e [Homo sapiens] 291 2e-78 gi|20149640 dual oxidase 1 precursor [Homo sapiens] 121 2e-27 gi|28872751 dual oxidase 1 precursor [Homo sapiens] 121 2e-27 gi|132566532 dual oxidase 2 precursor [Homo sapiens] 117 3e-26 gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1 prec... 50 9e-06 gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo... 47 8e-05 gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2 prec... 42 0.002 gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo s... 31 3.5 gi|33469919 minichromosome maintenance complex component 4 [Homo... 31 3.5 gi|33469917 minichromosome maintenance complex component 4 [Homo... 31 3.5 gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 31 4.5 gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 31 4.5 gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 31 4.5 >gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens] Length = 712 Score = 1463 bits (3788), Expect = 0.0 Identities = 712/712 (100%), Positives = 712/712 (100%) Query: 1 MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAM 60 MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAM Sbjct: 1 MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAM 60 Query: 61 SSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLE 120 SSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLE Sbjct: 61 SSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLE 120 Query: 121 VGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTP 180 VGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTP Sbjct: 121 VGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTP 180 Query: 181 GKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSE 240 GKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSE Sbjct: 181 GKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSE 240 Query: 241 YSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINAL 300 YSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINAL Sbjct: 241 YSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINAL 300 Query: 301 TSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTT 360 TSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTT Sbjct: 301 TSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTT 360 Query: 361 ARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAF 420 ARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAF Sbjct: 361 ARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAF 420 Query: 421 VQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDE 480 VQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDE Sbjct: 421 VQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDE 480 Query: 481 NYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQ 540 NYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQ Sbjct: 481 NYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQ 540 Query: 541 PTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGL 600 PTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGL Sbjct: 541 PTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGL 600 Query: 601 YGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDS 660 YGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDS Sbjct: 601 YGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDS 660 Query: 661 LQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN 712 LQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN Sbjct: 661 LQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN 712 >gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens] Length = 629 Score = 1266 bits (3276), Expect = 0.0 Identities = 605/612 (98%), Positives = 608/612 (99%) Query: 101 KASLTNVTDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRAL 160 +A+ + DPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRAL Sbjct: 18 QAAASTTRDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRAL 77 Query: 161 ARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQW 220 ARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQW Sbjct: 78 ARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQW 137 Query: 221 GQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRA 280 GQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRA Sbjct: 138 GQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRA 197 Query: 281 GFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHG 340 GFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHG Sbjct: 198 GFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHG 257 Query: 341 LPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRL 400 LPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRL Sbjct: 258 LPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRL 317 Query: 401 NPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF 460 NPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF Sbjct: 318 NPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF 377 Query: 461 TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKK 520 TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKK Sbjct: 378 TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKK 437 Query: 521 SKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQT 580 SKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQT Sbjct: 438 SKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQT 497 Query: 581 LEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIR 640 LEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIR Sbjct: 498 LEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIR 557 Query: 641 DGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAID 700 DGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAID Sbjct: 558 DGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAID 617 Query: 701 KLDLSPWASVKN 712 KLDLSPWASVKN Sbjct: 618 KLDLSPWASVKN 629 Score = 48.9 bits (115), Expect = 2e-05 Identities = 26/35 (74%), Positives = 30/35 (85%) Query: 1 MRVLLHLPALLASLILLQAAASTTRAQTTRTSAIS 35 MRVLLHLPALLASLILLQAAASTTR + +++S Sbjct: 1 MRVLLHLPALLASLILLQAAASTTRDPSLDLTSLS 35 >gi|4557759 myeloperoxidase [Homo sapiens] Length = 745 Score = 736 bits (1900), Expect = 0.0 Identities = 371/720 (51%), Positives = 490/720 (68%), Gaps = 18/720 (2%) Query: 1 MRVLLHLPALLASLILLQAAASTTRAQTTR--TSAISDTVSQAKVQVNKAFLDSRTRLKT 58 M++LL L LLA L Q + A TS + ++ +AK V+KA+ + R +K Sbjct: 27 MKLLLALAGLLAILATPQPSEGAAPAVLGEVDTSLVLSSMEEAKQLVDKAYKERRESIKQ 86 Query: 59 AMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKA--------SLTNVTDP 110 + S + + +L Y K TRTA+R +L L +K ++T+V P Sbjct: 87 RLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALDLLERKLRSLWRRPFNVTDVLTP 146 Query: 111 SLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYED 170 + L LS GC V C YRTITG CNNRR P LGA+NRA RWLPAEYED Sbjct: 147 A-QLNVLSKSSGCAYQDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYED 205 Query: 171 GLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDF 230 G SLP+GWTPG RNGFP+ LAR VSN+IV + ++ DQ RSL+FMQWGQ++DHDLDF Sbjct: 206 GFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDF 265 Query: 231 APDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYK 290 P+ +S + C+ C+Q CFP+ PPNDP+ Q C+PFFR+ CP P Sbjct: 266 TPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRS---CPACPGS 322 Query: 291 SLA-REQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSK 349 ++ R QINALTSF+DAS VY SE LA LRN+S+ LGL+AVNQ D+G LP+D+ Sbjct: 323 NITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNL 382 Query: 350 KPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKL 409 PC N +AR+PCFLAGD+R+SE L + HTL LREHNRLA ELK LNP+WDGE+L Sbjct: 383 HDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERL 442 Query: 410 YQEARKILGAFVQIITFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVFTFAFRFGH 468 YQEARKI+GA VQIIT+RDYLP++LG M+K++P Y+ Y++SVDPRI+NVFT AFR+GH Sbjct: 443 YQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGH 502 Query: 469 LEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNK 528 + MFRLD YQP P P +PL +FF +WR+V +GGIDP++RGL+A +KL +QN+ Sbjct: 503 TLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQ 562 Query: 529 MMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVL 588 + E+R +LF+ RI G DL A+N QR RDHG PGYN+WR FC L QP+T+ +L TVL Sbjct: 563 IAVDEIRERLFEQVMRI-GLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVL 621 Query: 589 KSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWE 648 ++ LA+KL+ YGTP+NIDIW+G ++EPL +GRVGPLLAC++G QF+++RDGDRFWWE Sbjct: 622 RNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWE 681 Query: 649 NPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDP-FWANSYPYDFVDCSAIDKLDLSPW 707 N GVF+ +Q+ +L ++S R++CDNT IT V ++ F +NSYP DFV+CS + L+L+ W Sbjct: 682 NEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASW 741 >gi|4503595 eosinophil peroxidase [Homo sapiens] Length = 715 Score = 727 bits (1877), Expect = 0.0 Identities = 373/719 (51%), Positives = 487/719 (67%), Gaps = 19/719 (2%) Query: 1 MRVLLHLPALLASLILLQAAASTTRAQ--TTRTSAISDTVSQAKVQVNKAFLDSRTRLKT 58 M +L L +LA+L+L Q T A TS + D +++AK+ V+ A+ ++ +K Sbjct: 1 MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQ 60 Query: 59 AMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKA--------SLTNV-TD 109 + S + + L Y K TRT +R +L L +K ++T+V T+ Sbjct: 61 RLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGPFNVTDVLTE 120 Query: 110 PSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYE 169 P L L LS GC RC YRTITG CNN+R+P LGA+N+ALARWLPAEYE Sbjct: 121 PQLRL--LSQASGCALRDQAERCS--DKYRTITGRCNNKRRPLLGASNQALARWLPAEYE 176 Query: 170 DGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLD 229 DGLSLPFGWTP + RNGF LPL R VSN+IV + NE D+ R+L+FMQWGQ +DHDLD Sbjct: 177 DGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLD 236 Query: 230 FAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPY 289 F+P++ + + C+ C Q CFPI PPNDP+ Q C+PFFR+ CP Sbjct: 237 FSPESPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQN-- 294 Query: 290 KSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSK 349 K+ R QINALTSF+DAS VY SE SL+ RLRN ++ LGL+A+NQ D+G LP+D+ Sbjct: 295 KNRVRNQINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNL 354 Query: 350 KPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKL 409 PC N +AR+PCFLAGD+R++E LA HTLF+REHNRLA EL+RLNP+W+G+KL Sbjct: 355 HDDPCLLTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKL 414 Query: 410 YQEARKILGAFVQIITFRDYLPILLGD-HMQKWIPPYQGYSESVDPRISNVFTFAFRFGH 468 Y EARKI+GA VQIIT+RD+LP++LG ++ + Y+GY +VDPR++NVFT AFRFGH Sbjct: 415 YNEARKIMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGH 474 Query: 469 LEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNK 528 + MFRLD Y+ P +PL + FF +WR+V +GGIDP++RGL+A +KL +Q+ Sbjct: 475 TMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDA 534 Query: 529 MMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVL 588 M+ ELR++LF+ RI G DLAA+N QR RDHG PGYN+WR FC LSQP+ L +L+ VL Sbjct: 535 MLVDELRDRLFRQVRRI-GLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVL 593 Query: 589 KSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWE 648 K++ LA+K L LYGTPDNIDIWIGAIAEPL+ RVGPLLACL QF++ RDGDRFWW+ Sbjct: 594 KNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQ 653 Query: 649 NPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707 GVFT Q+ +L ++S SR++CDNT IT V RD F AN YP FV+CS I +L+LS W Sbjct: 654 KRGVFTKRQRKALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAW 712 >gi|28558982 thyroid peroxidase isoform a [Homo sapiens] Length = 933 Score = 540 bits (1390), Expect = e-153 Identities = 304/701 (43%), Positives = 413/701 (58%), Gaps = 30/701 (4%) Query: 32 SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91 S +S + ++K V+ A + R +P QL + K + + R ++ Sbjct: 37 SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94 Query: 92 EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141 E S++ +++K +L + TD S DL S+ + GC +C + C + YR I Sbjct: 95 ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154 Query: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201 TG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+ ++ Sbjct: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214 Query: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMF 261 NE D S L M WGQ +DHD+ F P + ++ A C C + CFPI Sbjct: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274 Query: 262 PPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASFVYSS 312 P P AGT C+PF+R+ C T +L R+Q+N LTSFLDAS VY S Sbjct: 275 PEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGS 332 Query: 313 EPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVPCFLA 368 P+L +LRN +S GL+ V+ + D G YLP+ + P+ C I R PCFLA Sbjct: 333 SPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLA 392 Query: 369 GDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRD 428 GD RASE L HTL+LREHNRLA LK LN W + +YQEARK++GA QIIT RD Sbjct: 393 GDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRD 452 Query: 429 YLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWG 486 Y+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RLD ++Q Sbjct: 453 YIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHP 512 Query: 487 PEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIH 546 P L LH FF+ W +++ GG+DPL+RGLLA+ +KL Q+++M EL +LF ++ Sbjct: 513 DLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNS-S 571 Query: 547 GFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDN 606 DLA+IN QR RDHG PGYN WR FC L + +T +L+T + S+ +A K+L LY PDN Sbjct: 572 TLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDN 631 Query: 607 IDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSF 666 ID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ L+K S Sbjct: 632 IDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSL 691 Query: 667 SRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707 SR++CDNT +T+VP D F +P DF C +I ++L W Sbjct: 692 SRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 732 >gi|28558988 thyroid peroxidase isoform d [Homo sapiens] Length = 889 Score = 540 bits (1390), Expect = e-153 Identities = 304/701 (43%), Positives = 413/701 (58%), Gaps = 30/701 (4%) Query: 32 SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91 S +S + ++K V+ A + R +P QL + K + + R ++ Sbjct: 37 SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94 Query: 92 EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141 E S++ +++K +L + TD S DL S+ + GC +C + C + YR I Sbjct: 95 ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154 Query: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201 TG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+ ++ Sbjct: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214 Query: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMF 261 NE D S L M WGQ +DHD+ F P + ++ A C C + CFPI Sbjct: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274 Query: 262 PPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASFVYSS 312 P P AGT C+PF+R+ C T +L R+Q+N LTSFLDAS VY S Sbjct: 275 PEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGS 332 Query: 313 EPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVPCFLA 368 P+L +LRN +S GL+ V+ + D G YLP+ + P+ C I R PCFLA Sbjct: 333 SPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLA 392 Query: 369 GDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRD 428 GD RASE L HTL+LREHNRLA LK LN W + +YQEARK++GA QIIT RD Sbjct: 393 GDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRD 452 Query: 429 YLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWG 486 Y+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RLD ++Q Sbjct: 453 YIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHP 512 Query: 487 PEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIH 546 P L LH FF+ W +++ GG+DPL+RGLLA+ +KL Q+++M EL +LF ++ Sbjct: 513 DLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNS-S 571 Query: 547 GFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDN 606 DLA+IN QR RDHG PGYN WR FC L + +T +L+T + S+ +A K+L LY PDN Sbjct: 572 TLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDN 631 Query: 607 IDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSF 666 ID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ L+K S Sbjct: 632 IDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSL 691 Query: 667 SRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707 SR++CDNT +T+VP D F +P DF C +I ++L W Sbjct: 692 SRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 732 >gi|28558984 thyroid peroxidase isoform b [Homo sapiens] Length = 876 Score = 452 bits (1163), Expect = e-127 Identities = 275/701 (39%), Positives = 371/701 (52%), Gaps = 87/701 (12%) Query: 32 SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91 S +S + ++K V+ A + R +P QL + K + + R ++ Sbjct: 37 SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94 Query: 92 EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141 E S++ +++K +L + TD S DL S+ + GC +C + C + YR I Sbjct: 95 ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154 Query: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201 TG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+ ++ Sbjct: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214 Query: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMF 261 NE D S L M WGQ +DHD+ F P + ++ A C C + CFPI Sbjct: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274 Query: 262 PPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASFVYSS 312 P P AGT C+PF+R+ C T +L R+Q+N LTSFLDAS VY S Sbjct: 275 PEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGS 332 Query: 313 EPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVPCFLA 368 P+L +LRN +S GL+ V+ + D G YLP+ + P+ C I R PCFLA Sbjct: 333 SPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLA 392 Query: 369 GDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRD 428 GD RASE L HTL+LREHNRLA LK LN W + +YQEARK++GA QIIT RD Sbjct: 393 GDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRD 452 Query: 429 YLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWG 486 Y+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RLD ++Q Sbjct: 453 YIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQE-- 510 Query: 487 PEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIH 546 P+LP W L F P + Sbjct: 511 -HPDLP------GLW--------------------------------LHQAFFSPWTLLR 531 Query: 547 GFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDN 606 G GYN WR FC L + +T +L+T + S+ +A K+L LY PDN Sbjct: 532 G-----------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDN 574 Query: 607 IDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSF 666 ID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ L+K S Sbjct: 575 IDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSL 634 Query: 667 SRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707 SR++CDNT +T+VP D F +P DF C +I ++L W Sbjct: 635 SRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 675 >gi|109150416 peroxidasin [Homo sapiens] Length = 1479 Score = 451 bits (1159), Expect = e-126 Identities = 267/698 (38%), Positives = 389/698 (55%), Gaps = 33/698 (4%) Query: 34 ISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGR-TRTAIRNGQVWE 92 ++ ++ +A V++A +RT L S + L ++ + T R G+++E Sbjct: 624 VATSIVEAIATVDRAINSTRTHL---FDSRPRSPNDLLALFRYPRDPYTVEQARAGEIFE 680 Query: 93 ESLKRLRQKAS------LTNVTDPSLDLTS------LSLEVGCGAPAPVVRC-DPC--SP 137 +L+ +++ L + DL S ++ GC A V C D C Sbjct: 681 RTLQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLNLIANLSGCTAHRRVNNCSDMCFHQK 740 Query: 138 YRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSN 197 YRT G CNN + P GA+ A R L + YE+G + P G P + NG LP+ R VS Sbjct: 741 YRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVST 800 Query: 198 KIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQ-CDEYCIQGDNC 256 ++G E D+ + + MQWGQ +DHDLD + L + +S Q C C C Sbjct: 801 TLIG--TETVTPDEQFTHMLMQWGQFLDHDLD-STVVALSQARFSDGQHCSNVCSNDPPC 857 Query: 257 FPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLA-----REQINALTSFLDASFVYS 311 F +M PPND +A + +CM F R+ VC + L REQIN LTS++DAS VY Sbjct: 858 FSVMIPPNDSRARSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYG 917 Query: 312 SEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDS 371 S A +R+L+S GL+ V G P LP+ + P+ C + +PCFLAGD Sbjct: 918 STEHEARSIRDLASHRGLLRQGI-VQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDH 976 Query: 372 RASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLP 431 RA+E + L + HTL+ REHNR+A EL +LNP WDG+ +Y E RKI+GA +Q IT++ +LP Sbjct: 977 RANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLP 1036 Query: 432 ILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWGPEPE 490 +LG+ + + Y GY ++ I N F T AFRFGH V ++RLDEN+QP + Sbjct: 1037 KILGEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQD-H 1095 Query: 491 LPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDL 550 LPLH FF+ +R+V +GGIDPL+RGL K+ ++++ EL +LF H + DL Sbjct: 1096 LPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTV-ALDL 1154 Query: 551 AAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIW 610 AAIN QR RDHG P Y+ +R +C+LS T E+L +K+ + +KL LYG+ NID++ Sbjct: 1155 AAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLF 1214 Query: 611 IGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLV 670 + E LV R+GP L CLL QF+++RDGDR W+ENPGVF+ Q +++ S +R++ Sbjct: 1215 PALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLARIL 1274 Query: 671 CDNT-RITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707 CDN IT+V D F +P+ + C I ++DL W Sbjct: 1275 CDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVW 1312 >gi|126517478 peroxidasin homolog-like [Homo sapiens] Length = 1463 Score = 398 bits (1022), Expect = e-110 Identities = 250/646 (38%), Positives = 349/646 (54%), Gaps = 34/646 (5%) Query: 86 RNGQVWEESLKRLRQKASLTNVTDPS---------LDLTSLSLEV---GCGAPAPVVRC- 132 R G+++E +L+ +R++ D + SLSL GC A P+ C Sbjct: 660 RAGEIFEHTLQLIRERVKQGLTVDLEGKEFRYNDLVSPRSLSLIANLSGCTARRPLPNCS 719 Query: 133 DPC--SPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGW-TPGKTRNGFPL 189 + C + YR G CNN ++P GAA A AR L Y DG+ P G P +R PL Sbjct: 720 NRCFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVGSRQ--PL 777 Query: 190 PLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQ-CDE 248 P R V+ V D + + + M WG ++HDLD L ++ +S + C Sbjct: 778 PPPRLVAT--VWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPA-LSTARFSDGRPCSS 834 Query: 249 YCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVC----PTPPYKSL-AREQINALTSF 303 C CFP+ DP+ GT CM F R+ C P+ S+ AREQIN T++ Sbjct: 835 VCTNDPPCFPMNTRHADPR-GTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQTAY 893 Query: 304 LDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARV 363 +D S VY S + LR+ S P GL+ G P LP+ + P+ C Sbjct: 894 IDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECA--RQEQES 951 Query: 364 PCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQI 423 PCFLAGD RA+EH+ LA HTL+ REHNR+A EL LNP W+G +YQEARKI+GA +Q Sbjct: 952 PCFLAGDHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVGAELQH 1011 Query: 424 ITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENY 482 IT+ +LP +LGD + + Y+GY+ +V+ I N F T AFRFGH + ++RL+ Sbjct: 1012 ITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATL 1071 Query: 483 QPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPT 542 E LP H F+ R++K+GGIDP++RGL +K + +++ EL +LF Sbjct: 1072 GEIS-EGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAA 1130 Query: 543 HRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYG 602 + D AA QR RDHG P Y +R FC+L+ + E+L +K + +KL LYG Sbjct: 1131 YSA-AVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYG 1189 Query: 603 TPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQ 662 +P +ID+W + E L+ RVGP L CL QFQ++RDGDRFW+ENPGVFT Q L+ Sbjct: 1190 SPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLK 1249 Query: 663 KMSFSRLVCDN-TRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707 + S SR++CDN I +V D F YP D+++CS I K+DL W Sbjct: 1250 QASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVW 1295 >gi|28558990 thyroid peroxidase isoform e [Homo sapiens] Length = 760 Score = 291 bits (744), Expect = 2e-78 Identities = 139/289 (48%), Positives = 195/289 (67%), Gaps = 3/289 (1%) Query: 421 VQIITFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRL 478 +QIIT RDY+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RL Sbjct: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331 Query: 479 DENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKL 538 D ++Q P L LH FF+ W +++ GG+DPL+RGLLA+ +KL Q+++M EL +L Sbjct: 332 DASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERL 391 Query: 539 FQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLL 598 F ++ DLA+IN QR RDHG PGYN WR FC L + +T +L+T + S+ +A K+L Sbjct: 392 FVLSNS-STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKIL 450 Query: 599 GLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQK 658 LY PDNID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ Sbjct: 451 DLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQR 510 Query: 659 DSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707 L+K S SR++CDNT +T+VP D F +P DF C +I ++L W Sbjct: 511 RELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 559 Score = 128 bits (321), Expect = 2e-29 Identities = 85/238 (35%), Positives = 119/238 (50%), Gaps = 12/238 (5%) Query: 32 SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91 S +S + ++K V+ A + R +P QL + K + + R ++ Sbjct: 37 SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94 Query: 92 EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141 E S++ +++K +L + TD S DL S+ + GC +C + C + YR I Sbjct: 95 ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154 Query: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201 TG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+ ++ Sbjct: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214 Query: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPI 259 NE D S L M WGQ +DHD+ F P + ++ A C C + CFPI Sbjct: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPI 272 >gi|20149640 dual oxidase 1 precursor [Homo sapiens] Length = 1551 Score = 121 bits (304), Expect = 2e-27 Identities = 148/565 (26%), Positives = 245/565 (43%), Gaps = 71/565 (12%) Query: 124 GAPAPVVRCDPCS-PYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGK 182 GA P+ +P S + G NN + G+ L R +PA Y DG+ P G Sbjct: 14 GAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH-- 71 Query: 183 TRNGFPLPLAREVSNKIVGYLNEEGVLD-QNRSLLFMQWGQIVDHDLDFAPDTELGSSEY 241 LP R++SN I G+ +NR++L + +G V DL + +T +E+ Sbjct: 72 ------LPNPRDLSNTISR--GPAGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPAEF 122 Query: 242 SKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK---CMPFFRAGFVCPTPPYKSLAREQIN 298 I PP DP + +PF R+ + T S R+ N Sbjct: 123 LN---------------IRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPAN 167 Query: 299 ALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKP-----SP 353 +T +LD S +Y S S + LR+ S G +A + P P DS+ P +P Sbjct: 168 QVTGWLDGSAIYGSSHSWSDALRSFSR--GQLASGPD------PAFPRDSQNPLLMWAAP 219 Query: 354 CEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEA 413 + G R + L L+ R HN A+ L R +P W+ E+L+Q A Sbjct: 220 DPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHA 279 Query: 414 RKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAF-RFGHLEVP 472 RK + A Q I ++LP L QK +P Y GY +DP IS+ F A +F VP Sbjct: 280 RKRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVP 335 Query: 473 SSMFRLDENYQPWG---PEPELPLHTLFFNTW------RMVKDGGIDPLVRGLLAKKSKL 523 ++ + + G + N++ + +D L+ G+ ++ ++ Sbjct: 336 PGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE- 394 Query: 524 MKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEE 583 +++ ++ ++R+ P + D A QR RD G P Y RA LS ++ Sbjct: 395 -REDHVLVEDVRDFWPGPL-KFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQD 452 Query: 584 LNTVL--KSKMLAKKLLGLYGTPDNIDI-WIGAIAEPLVERGR-VGPLLACLLGKQFQQI 639 +N L + + + LY N D+ W+ + L+E R GPL + ++ +QF ++ Sbjct: 453 INPALSRSNDTVLEATAALY----NQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRL 508 Query: 640 RDGDRFWWENP--GVFTNEQKDSLQ 662 RDGDR+W+EN G+F+ ++ + ++ Sbjct: 509 RDGDRYWFENTRNGLFSKKEIEEIR 533 >gi|28872751 dual oxidase 1 precursor [Homo sapiens] Length = 1551 Score = 121 bits (304), Expect = 2e-27 Identities = 148/565 (26%), Positives = 245/565 (43%), Gaps = 71/565 (12%) Query: 124 GAPAPVVRCDPCS-PYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGK 182 GA P+ +P S + G NN + G+ L R +PA Y DG+ P G Sbjct: 14 GAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH-- 71 Query: 183 TRNGFPLPLAREVSNKIVGYLNEEGVLD-QNRSLLFMQWGQIVDHDLDFAPDTELGSSEY 241 LP R++SN I G+ +NR++L + +G V DL + +T +E+ Sbjct: 72 ------LPNPRDLSNTISR--GPAGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPAEF 122 Query: 242 SKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK---CMPFFRAGFVCPTPPYKSLAREQIN 298 I PP DP + +PF R+ + T S R+ N Sbjct: 123 LN---------------IRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPAN 167 Query: 299 ALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKP-----SP 353 +T +LD S +Y S S + LR+ S G +A + P P DS+ P +P Sbjct: 168 QVTGWLDGSAIYGSSHSWSDALRSFSR--GQLASGPD------PAFPRDSQNPLLMWAAP 219 Query: 354 CEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEA 413 + G R + L L+ R HN A+ L R +P W+ E+L+Q A Sbjct: 220 DPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHA 279 Query: 414 RKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAF-RFGHLEVP 472 RK + A Q I ++LP L QK +P Y GY +DP IS+ F A +F VP Sbjct: 280 RKRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVP 335 Query: 473 SSMFRLDENYQPWG---PEPELPLHTLFFNTW------RMVKDGGIDPLVRGLLAKKSKL 523 ++ + + G + N++ + +D L+ G+ ++ ++ Sbjct: 336 PGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE- 394 Query: 524 MKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEE 583 +++ ++ ++R+ P + D A QR RD G P Y RA LS ++ Sbjct: 395 -REDHVLVEDVRDFWPGPL-KFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQD 452 Query: 584 LNTVL--KSKMLAKKLLGLYGTPDNIDI-WIGAIAEPLVERGR-VGPLLACLLGKQFQQI 639 +N L + + + LY N D+ W+ + L+E R GPL + ++ +QF ++ Sbjct: 453 INPALSRSNDTVLEATAALY----NQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRL 508 Query: 640 RDGDRFWWENP--GVFTNEQKDSLQ 662 RDGDR+W+EN G+F+ ++ + ++ Sbjct: 509 RDGDRYWFENTRNGLFSKKEIEEIR 533 >gi|132566532 dual oxidase 2 precursor [Homo sapiens] Length = 1548 Score = 117 bits (294), Expect = 3e-26 Identities = 153/588 (26%), Positives = 245/588 (41%), Gaps = 92/588 (15%) Query: 102 ASLTNVTDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALA 161 A LT PS + +LSL P V R D G NN R GA L Sbjct: 14 ALLTGSLGPSGNQDALSL------PWEVQRYD---------GWFNNLRHHERGAVGCRLQ 58 Query: 162 RWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWG 221 R +PA Y DG+ + LP R +SN + L NR++L + +G Sbjct: 59 RRVPANYADGVY--------QALEEPQLPNPRRLSNAATRGIAGLPSL-HNRTVLGVFFG 109 Query: 222 QIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK---CMPFF 278 V D+ + +T +E+ I PP DP + +PF Sbjct: 110 YHVLSDV-VSVETPGCPAEFLN---------------IRIPPGDPVFDPDQRGDVVLPFQ 153 Query: 279 RAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSD 338 R+ + T S R+ N +T +LD S +Y S S + LR+ S G +A + Sbjct: 154 RSRWDPETGRSPSNPRDLANQVTGWLDGSAIYGSSHSWSDALRSFSG--GQLASGPD--- 208 Query: 339 HGLPYLPYDSKKP-----SPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRL 393 P P DS+ P +P + G R + L L+ R HN Sbjct: 209 ---PAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLW 265 Query: 394 ARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVD 453 A+ L R +P W+ E+L+Q ARK + A Q I ++LP L QK +P Y GY +D Sbjct: 266 AQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLD 321 Query: 454 PRISNVFTFAF-RFGHLEVPSSMFR----------LDENYQPWGPEPELPLHTLFFNTW- 501 P IS F A +F VP ++ L++ +Q + N W Sbjct: 322 PSISPEFVVASEQFFSTMVPPGVYMRNASCHFRKVLNKGFQ------SSQALRVCNNYWI 375 Query: 502 ----RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQR 557 + ++ L+ G+ ++ S+L ++ ++ +LR+ P + D A + QR Sbjct: 376 RENPNLNSTQEVNELLLGMASQISEL--EDNIVVEDLRDYWPGP-GKFSRTDYVASSIQR 432 Query: 558 CRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTP-DNIDIWIGAIAE 616 RD G P Y+ L P+ +LN + ++L + LY +++ +G + E Sbjct: 433 GRDMGLPSYSQALLAFGLDIPRNWSDLNPNVDPQVL-EATAALYNQDLSQLELLLGGLLE 491 Query: 617 PLVERGRVGPLLACLLGKQFQQIRDGDRFWWENP--GVFTNEQKDSLQ 662 G GPL + ++ QF ++RDGDR+W+EN G+F+ ++ + ++ Sbjct: 492 ---SHGDPGPLFSAIVLDQFVRLRDGDRYWFENTRNGLFSKKEIEDIR 536 >gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1 precursor [Homo sapiens] Length = 599 Score = 49.7 bits (117), Expect = 9e-06 Identities = 75/305 (24%), Positives = 120/305 (39%), Gaps = 47/305 (15%) Query: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 443 TL+LREHNR+ LK +P W E+L+Q R IL I +Y+ L G +Q Sbjct: 302 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD 361 Query: 444 P--YQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTW 501 P G RI+ F + + H +P S F++ E FNT Sbjct: 362 PELLFGVQFQYRNRIAMEFNHLYHW-HPLMPDS-FKVGSQ--------EYSYEQFLFNT- 410 Query: 502 RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDH 561 M+ D G++ LV ++ + G + H +H +A + R+ Sbjct: 411 SMLVDYGVEALVDAF----------SRQIAGRIGGGRNMDHHILH---VAVDVIRESREM 457 Query: 562 GQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAI------- 614 +N +R + + +EL + K +A +L LYG D ++ + G + Sbjct: 458 RLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPN 514 Query: 615 ---AEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQK-MSFSRLV 670 E ++E G L LLG +W P F E ++ K + +LV Sbjct: 515 SIFGESMIEIGAPFSLKG-LLGNPI----CSPEYW--KPSTFGGEVGFNIVKTATLKKLV 567 Query: 671 CDNTR 675 C NT+ Sbjct: 568 CLNTK 572 >gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo sapiens] Length = 604 Score = 46.6 bits (109), Expect = 8e-05 Identities = 24/61 (39%), Positives = 35/61 (57%) Query: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 443 T++LREHNR+ LK+ +P+W E+L+Q +R IL I DY+ L G H + Sbjct: 289 TIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFD 348 Query: 444 P 444 P Sbjct: 349 P 349 >gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2 precursor [Homo sapiens] Length = 562 Score = 42.0 bits (97), Expect = 0.002 Identities = 24/61 (39%), Positives = 32/61 (52%) Query: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 443 TL+LREHNR+ LK +P W E+L+Q R IL I +Y+ L G +Q Sbjct: 302 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD 361 Query: 444 P 444 P Sbjct: 362 P 362 >gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo sapiens] Length = 439 Score = 31.2 bits (69), Expect = 3.5 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 1/90 (1%) Query: 12 ASLILLQAAASTTRAQTTRTSAISDTVSQAKVQV-NKAFLDSRTRLKTAMSSETPTSRQL 70 +S L++AAA ++ TRT D S V++ +A LD+R + S+ T +S Sbjct: 252 SSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKSVSDKQSAVTESSEGT 311 Query: 71 SEYLKHAKGRTRTAIRNGQVWEESLKRLRQ 100 L+ K + +++G ++ K+ R+ Sbjct: 312 VSLLRSHKNLFLSKLQHGTQQQDLNKKERR 341 >gi|33469919 minichromosome maintenance complex component 4 [Homo sapiens] Length = 863 Score = 31.2 bits (69), Expect = 3.5 Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 6/96 (6%) Query: 26 AQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAI 85 A +T +S+ SQA ++ A++D R ++ ++ + RQL ++ A+ + + Sbjct: 694 AHSTIMPRLSEEASQALIE---AYVDMR-KIGSSRGMVSAYPRQLESLIRLAEAHAKVRL 749 Query: 86 RNG--QVWEESLKRLRQKASLTNVTDPSLDLTSLSL 119 N + E KRL ++A + TDP + +S+ Sbjct: 750 SNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISI 785 >gi|33469917 minichromosome maintenance complex component 4 [Homo sapiens] Length = 863 Score = 31.2 bits (69), Expect = 3.5 Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 6/96 (6%) Query: 26 AQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAI 85 A +T +S+ SQA ++ A++D R ++ ++ + RQL ++ A+ + + Sbjct: 694 AHSTIMPRLSEEASQALIE---AYVDMR-KIGSSRGMVSAYPRQLESLIRLAEAHAKVRL 749 Query: 86 RNG--QVWEESLKRLRQKASLTNVTDPSLDLTSLSL 119 N + E KRL ++A + TDP + +S+ Sbjct: 750 SNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISI 785 >gi|4557665 insulin-like growth factor 1 receptor precursor [Homo sapiens] Length = 1367 Score = 30.8 bits (68), Expect = 4.5 Identities = 27/114 (23%), Positives = 41/114 (35%), Gaps = 4/114 (3%) Query: 71 SEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPS---LDLTSLSLEVGCGAPA 127 S ++ + + R ++ S R A N+TDP + V Sbjct: 729 SIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERT 788 Query: 128 PVVRCDPCSPYRTITGDCNNR-RKPALGAANRALARWLPAEYEDGLSLPFGWTP 180 + P + YR CN+ K A+N AR +PAE D + P W P Sbjct: 789 VISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEP 842 >gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] Length = 1220 Score = 30.8 bits (68), Expect = 4.5 Identities = 16/59 (27%), Positives = 29/59 (49%) Query: 42 KVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQ 100 +VQ N DS LK A+ ++ + L + L + TR+ ++ ++ LK LR+ Sbjct: 554 QVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELRE 612 >gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] Length = 1721 Score = 30.8 bits (68), Expect = 4.5 Identities = 16/59 (27%), Positives = 29/59 (49%) Query: 42 KVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQ 100 +VQ N DS LK A+ ++ + L + L + TR+ ++ ++ LK LR+ Sbjct: 554 QVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELRE 612 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,212,977 Number of Sequences: 37866 Number of extensions: 1303301 Number of successful extensions: 3055 Number of sequences better than 10.0: 22 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 4 Number of HSP's that attempted gapping in prelim test: 2971 Number of HSP's gapped (non-prelim): 32 length of query: 712 length of database: 18,247,518 effective HSP length: 109 effective length of query: 603 effective length of database: 14,120,124 effective search space: 8514434772 effective search space used: 8514434772 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.