Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 40549418

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo
sapiens]
         (712 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]   1463   0.0  
gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]  1266   0.0  
gi|4557759 myeloperoxidase [Homo sapiens]                             736   0.0  
gi|4503595 eosinophil peroxidase [Homo sapiens]                       727   0.0  
gi|28558982 thyroid peroxidase isoform a [Homo sapiens]               540   e-153
gi|28558988 thyroid peroxidase isoform d [Homo sapiens]               540   e-153
gi|28558984 thyroid peroxidase isoform b [Homo sapiens]               452   e-127
gi|109150416 peroxidasin [Homo sapiens]                               451   e-126
gi|126517478 peroxidasin homolog-like [Homo sapiens]                  398   e-110
gi|28558990 thyroid peroxidase isoform e [Homo sapiens]               291   2e-78
gi|20149640 dual oxidase 1 precursor [Homo sapiens]                   121   2e-27
gi|28872751 dual oxidase 1 precursor [Homo sapiens]                   121   2e-27
gi|132566532 dual oxidase 2 precursor [Homo sapiens]                  117   3e-26
gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1 prec...    50   9e-06
gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo...    47   8e-05
gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2 prec...    42   0.002
gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo s...    31   3.5  
gi|33469919 minichromosome maintenance complex component 4 [Homo...    31   3.5  
gi|33469917 minichromosome maintenance complex component 4 [Homo...    31   3.5  
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo...    31   4.5  
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                31   4.5  
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                31   4.5  

>gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]
          Length = 712

 Score = 1463 bits (3788), Expect = 0.0
 Identities = 712/712 (100%), Positives = 712/712 (100%)

Query: 1   MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAM 60
           MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAM
Sbjct: 1   MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAM 60

Query: 61  SSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLE 120
           SSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLE
Sbjct: 61  SSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLE 120

Query: 121 VGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTP 180
           VGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTP
Sbjct: 121 VGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTP 180

Query: 181 GKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSE 240
           GKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSE
Sbjct: 181 GKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSE 240

Query: 241 YSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINAL 300
           YSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINAL
Sbjct: 241 YSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINAL 300

Query: 301 TSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTT 360
           TSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTT
Sbjct: 301 TSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTT 360

Query: 361 ARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAF 420
           ARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAF
Sbjct: 361 ARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAF 420

Query: 421 VQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDE 480
           VQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDE
Sbjct: 421 VQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDE 480

Query: 481 NYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQ 540
           NYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQ
Sbjct: 481 NYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQ 540

Query: 541 PTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGL 600
           PTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGL
Sbjct: 541 PTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGL 600

Query: 601 YGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDS 660
           YGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDS
Sbjct: 601 YGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDS 660

Query: 661 LQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN 712
           LQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN
Sbjct: 661 LQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN 712


>gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]
          Length = 629

 Score = 1266 bits (3276), Expect = 0.0
 Identities = 605/612 (98%), Positives = 608/612 (99%)

Query: 101 KASLTNVTDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRAL 160
           +A+ +   DPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRAL
Sbjct: 18  QAAASTTRDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRAL 77

Query: 161 ARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQW 220
           ARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQW
Sbjct: 78  ARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQW 137

Query: 221 GQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRA 280
           GQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRA
Sbjct: 138 GQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRA 197

Query: 281 GFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHG 340
           GFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHG
Sbjct: 198 GFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHG 257

Query: 341 LPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRL 400
           LPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRL
Sbjct: 258 LPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRL 317

Query: 401 NPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF 460
           NPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF
Sbjct: 318 NPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF 377

Query: 461 TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKK 520
           TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKK
Sbjct: 378 TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKK 437

Query: 521 SKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQT 580
           SKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQT
Sbjct: 438 SKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQT 497

Query: 581 LEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIR 640
           LEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIR
Sbjct: 498 LEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIR 557

Query: 641 DGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAID 700
           DGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAID
Sbjct: 558 DGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAID 617

Query: 701 KLDLSPWASVKN 712
           KLDLSPWASVKN
Sbjct: 618 KLDLSPWASVKN 629



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 26/35 (74%), Positives = 30/35 (85%)

Query: 1  MRVLLHLPALLASLILLQAAASTTRAQTTRTSAIS 35
          MRVLLHLPALLASLILLQAAASTTR  +   +++S
Sbjct: 1  MRVLLHLPALLASLILLQAAASTTRDPSLDLTSLS 35


>gi|4557759 myeloperoxidase [Homo sapiens]
          Length = 745

 Score =  736 bits (1900), Expect = 0.0
 Identities = 371/720 (51%), Positives = 490/720 (68%), Gaps = 18/720 (2%)

Query: 1   MRVLLHLPALLASLILLQAAASTTRAQTTR--TSAISDTVSQAKVQVNKAFLDSRTRLKT 58
           M++LL L  LLA L   Q +     A      TS +  ++ +AK  V+KA+ + R  +K 
Sbjct: 27  MKLLLALAGLLAILATPQPSEGAAPAVLGEVDTSLVLSSMEEAKQLVDKAYKERRESIKQ 86

Query: 59  AMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKA--------SLTNVTDP 110
            + S + +  +L  Y K     TRTA+R       +L  L +K         ++T+V  P
Sbjct: 87  RLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALDLLERKLRSLWRRPFNVTDVLTP 146

Query: 111 SLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYED 170
           +  L  LS   GC      V C     YRTITG CNNRR P LGA+NRA  RWLPAEYED
Sbjct: 147 A-QLNVLSKSSGCAYQDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYED 205

Query: 171 GLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDF 230
           G SLP+GWTPG  RNGFP+ LAR VSN+IV +  ++   DQ RSL+FMQWGQ++DHDLDF
Sbjct: 206 GFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDF 265

Query: 231 APDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYK 290
            P+    +S  +   C+  C+Q   CFP+  PPNDP+   Q  C+PFFR+   CP  P  
Sbjct: 266 TPEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRS---CPACPGS 322

Query: 291 SLA-REQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSK 349
           ++  R QINALTSF+DAS VY SE  LA  LRN+S+ LGL+AVNQ   D+G   LP+D+ 
Sbjct: 323 NITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNL 382

Query: 350 KPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKL 409
              PC   N +AR+PCFLAGD+R+SE   L + HTL LREHNRLA ELK LNP+WDGE+L
Sbjct: 383 HDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERL 442

Query: 410 YQEARKILGAFVQIITFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVFTFAFRFGH 468
           YQEARKI+GA VQIIT+RDYLP++LG   M+K++P Y+ Y++SVDPRI+NVFT AFR+GH
Sbjct: 443 YQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGH 502

Query: 469 LEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNK 528
             +   MFRLD  YQP  P P +PL  +FF +WR+V +GGIDP++RGL+A  +KL +QN+
Sbjct: 503 TLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQ 562

Query: 529 MMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVL 588
           +   E+R +LF+   RI G DL A+N QR RDHG PGYN+WR FC L QP+T+ +L TVL
Sbjct: 563 IAVDEIRERLFEQVMRI-GLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVL 621

Query: 589 KSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWE 648
           ++  LA+KL+  YGTP+NIDIW+G ++EPL  +GRVGPLLAC++G QF+++RDGDRFWWE
Sbjct: 622 RNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWE 681

Query: 649 NPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDP-FWANSYPYDFVDCSAIDKLDLSPW 707
           N GVF+ +Q+ +L ++S  R++CDNT IT V ++  F +NSYP DFV+CS +  L+L+ W
Sbjct: 682 NEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASW 741


>gi|4503595 eosinophil peroxidase [Homo sapiens]
          Length = 715

 Score =  727 bits (1877), Expect = 0.0
 Identities = 373/719 (51%), Positives = 487/719 (67%), Gaps = 19/719 (2%)

Query: 1   MRVLLHLPALLASLILLQAAASTTRAQ--TTRTSAISDTVSQAKVQVNKAFLDSRTRLKT 58
           M +L  L  +LA+L+L Q    T  A      TS + D +++AK+ V+ A+  ++  +K 
Sbjct: 1   MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQ 60

Query: 59  AMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKA--------SLTNV-TD 109
            + S + +   L  Y K     TRT +R       +L  L +K         ++T+V T+
Sbjct: 61  RLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGPFNVTDVLTE 120

Query: 110 PSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYE 169
           P L L  LS   GC       RC     YRTITG CNN+R+P LGA+N+ALARWLPAEYE
Sbjct: 121 PQLRL--LSQASGCALRDQAERCS--DKYRTITGRCNNKRRPLLGASNQALARWLPAEYE 176

Query: 170 DGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLD 229
           DGLSLPFGWTP + RNGF LPL R VSN+IV + NE    D+ R+L+FMQWGQ +DHDLD
Sbjct: 177 DGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLD 236

Query: 230 FAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPY 289
           F+P++    +  +   C+  C Q   CFPI  PPNDP+   Q  C+PFFR+   CP    
Sbjct: 237 FSPESPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQN-- 294

Query: 290 KSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSK 349
           K+  R QINALTSF+DAS VY SE SL+ RLRN ++ LGL+A+NQ   D+G   LP+D+ 
Sbjct: 295 KNRVRNQINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNL 354

Query: 350 KPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKL 409
              PC   N +AR+PCFLAGD+R++E   LA  HTLF+REHNRLA EL+RLNP+W+G+KL
Sbjct: 355 HDDPCLLTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKL 414

Query: 410 YQEARKILGAFVQIITFRDYLPILLGD-HMQKWIPPYQGYSESVDPRISNVFTFAFRFGH 468
           Y EARKI+GA VQIIT+RD+LP++LG    ++ +  Y+GY  +VDPR++NVFT AFRFGH
Sbjct: 415 YNEARKIMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGH 474

Query: 469 LEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNK 528
             +   MFRLD  Y+   P   +PL + FF +WR+V +GGIDP++RGL+A  +KL +Q+ 
Sbjct: 475 TMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDA 534

Query: 529 MMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVL 588
           M+  ELR++LF+   RI G DLAA+N QR RDHG PGYN+WR FC LSQP+ L +L+ VL
Sbjct: 535 MLVDELRDRLFRQVRRI-GLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVL 593

Query: 589 KSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWE 648
           K++ LA+K L LYGTPDNIDIWIGAIAEPL+   RVGPLLACL   QF++ RDGDRFWW+
Sbjct: 594 KNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQ 653

Query: 649 NPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
             GVFT  Q+ +L ++S SR++CDNT IT V RD F AN YP  FV+CS I +L+LS W
Sbjct: 654 KRGVFTKRQRKALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAW 712


>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
          Length = 933

 Score =  540 bits (1390), Expect = e-153
 Identities = 304/701 (43%), Positives = 413/701 (58%), Gaps = 30/701 (4%)

Query: 32  SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91
           S +S  + ++K  V+ A   +  R        +P   QL  + K  +  +    R  ++ 
Sbjct: 37  SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94

Query: 92  EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141
           E S++ +++K +L      + TD  S DL S+   + GC       +C + C  + YR I
Sbjct: 95  ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154

Query: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201
           TG CNNR  P  GA+N ALARWLP  YEDG S P GW PG   NGFPLP  REV+  ++ 
Sbjct: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214

Query: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMF 261
             NE    D   S L M WGQ +DHD+ F P +   ++    A C   C   + CFPI  
Sbjct: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274

Query: 262 PPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASFVYSS 312
           P    P AGT   C+PF+R+   C T    +L         R+Q+N LTSFLDAS VY S
Sbjct: 275 PEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGS 332

Query: 313 EPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVPCFLA 368
            P+L  +LRN +S  GL+ V+  + D G  YLP+   + P+ C     I    R PCFLA
Sbjct: 333 SPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLA 392

Query: 369 GDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRD 428
           GD RASE   L   HTL+LREHNRLA  LK LN  W  + +YQEARK++GA  QIIT RD
Sbjct: 393 GDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRD 452

Query: 429 YLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWG 486
           Y+P +LG +  Q+++ PY+GY  + +P +SNVF T AFRFGH  +   + RLD ++Q   
Sbjct: 453 YIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHP 512

Query: 487 PEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIH 546
             P L LH  FF+ W +++ GG+DPL+RGLLA+ +KL  Q+++M  EL  +LF  ++   
Sbjct: 513 DLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNS-S 571

Query: 547 GFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDN 606
             DLA+IN QR RDHG PGYN WR FC L + +T  +L+T + S+ +A K+L LY  PDN
Sbjct: 572 TLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDN 631

Query: 607 IDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSF 666
           ID+W+G +AE  + R R GPL ACL+GKQ + +RDGD FWWEN  VFT+ Q+  L+K S 
Sbjct: 632 IDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSL 691

Query: 667 SRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
           SR++CDNT +T+VP D F    +P DF  C +I  ++L  W
Sbjct: 692 SRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 732


>gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
          Length = 889

 Score =  540 bits (1390), Expect = e-153
 Identities = 304/701 (43%), Positives = 413/701 (58%), Gaps = 30/701 (4%)

Query: 32  SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91
           S +S  + ++K  V+ A   +  R        +P   QL  + K  +  +    R  ++ 
Sbjct: 37  SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94

Query: 92  EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141
           E S++ +++K +L      + TD  S DL S+   + GC       +C + C  + YR I
Sbjct: 95  ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154

Query: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201
           TG CNNR  P  GA+N ALARWLP  YEDG S P GW PG   NGFPLP  REV+  ++ 
Sbjct: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214

Query: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMF 261
             NE    D   S L M WGQ +DHD+ F P +   ++    A C   C   + CFPI  
Sbjct: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274

Query: 262 PPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASFVYSS 312
           P    P AGT   C+PF+R+   C T    +L         R+Q+N LTSFLDAS VY S
Sbjct: 275 PEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGS 332

Query: 313 EPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVPCFLA 368
            P+L  +LRN +S  GL+ V+  + D G  YLP+   + P+ C     I    R PCFLA
Sbjct: 333 SPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLA 392

Query: 369 GDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRD 428
           GD RASE   L   HTL+LREHNRLA  LK LN  W  + +YQEARK++GA  QIIT RD
Sbjct: 393 GDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRD 452

Query: 429 YLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWG 486
           Y+P +LG +  Q+++ PY+GY  + +P +SNVF T AFRFGH  +   + RLD ++Q   
Sbjct: 453 YIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHP 512

Query: 487 PEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIH 546
             P L LH  FF+ W +++ GG+DPL+RGLLA+ +KL  Q+++M  EL  +LF  ++   
Sbjct: 513 DLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNS-S 571

Query: 547 GFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDN 606
             DLA+IN QR RDHG PGYN WR FC L + +T  +L+T + S+ +A K+L LY  PDN
Sbjct: 572 TLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDN 631

Query: 607 IDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSF 666
           ID+W+G +AE  + R R GPL ACL+GKQ + +RDGD FWWEN  VFT+ Q+  L+K S 
Sbjct: 632 IDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSL 691

Query: 667 SRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
           SR++CDNT +T+VP D F    +P DF  C +I  ++L  W
Sbjct: 692 SRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 732


>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
          Length = 876

 Score =  452 bits (1163), Expect = e-127
 Identities = 275/701 (39%), Positives = 371/701 (52%), Gaps = 87/701 (12%)

Query: 32  SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91
           S +S  + ++K  V+ A   +  R        +P   QL  + K  +  +    R  ++ 
Sbjct: 37  SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94

Query: 92  EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141
           E S++ +++K +L      + TD  S DL S+   + GC       +C + C  + YR I
Sbjct: 95  ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154

Query: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201
           TG CNNR  P  GA+N ALARWLP  YEDG S P GW PG   NGFPLP  REV+  ++ 
Sbjct: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214

Query: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMF 261
             NE    D   S L M WGQ +DHD+ F P +   ++    A C   C   + CFPI  
Sbjct: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274

Query: 262 PPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASFVYSS 312
           P    P AGT   C+PF+R+   C T    +L         R+Q+N LTSFLDAS VY S
Sbjct: 275 PEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGS 332

Query: 313 EPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVPCFLA 368
            P+L  +LRN +S  GL+ V+  + D G  YLP+   + P+ C     I    R PCFLA
Sbjct: 333 SPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLA 392

Query: 369 GDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRD 428
           GD RASE   L   HTL+LREHNRLA  LK LN  W  + +YQEARK++GA  QIIT RD
Sbjct: 393 GDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRD 452

Query: 429 YLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWG 486
           Y+P +LG +  Q+++ PY+GY  + +P +SNVF T AFRFGH  +   + RLD ++Q   
Sbjct: 453 YIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQE-- 510

Query: 487 PEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIH 546
             P+LP        W                                L    F P   + 
Sbjct: 511 -HPDLP------GLW--------------------------------LHQAFFSPWTLLR 531

Query: 547 GFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDN 606
           G                 GYN WR FC L + +T  +L+T + S+ +A K+L LY  PDN
Sbjct: 532 G-----------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDN 574

Query: 607 IDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSF 666
           ID+W+G +AE  + R R GPL ACL+GKQ + +RDGD FWWEN  VFT+ Q+  L+K S 
Sbjct: 575 IDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSL 634

Query: 667 SRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
           SR++CDNT +T+VP D F    +P DF  C +I  ++L  W
Sbjct: 635 SRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 675


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score =  451 bits (1159), Expect = e-126
 Identities = 267/698 (38%), Positives = 389/698 (55%), Gaps = 33/698 (4%)

Query: 34   ISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGR-TRTAIRNGQVWE 92
            ++ ++ +A   V++A   +RT L     S   +   L    ++ +   T    R G+++E
Sbjct: 624  VATSIVEAIATVDRAINSTRTHL---FDSRPRSPNDLLALFRYPRDPYTVEQARAGEIFE 680

Query: 93   ESLKRLRQKAS------LTNVTDPSLDLTS------LSLEVGCGAPAPVVRC-DPC--SP 137
             +L+ +++         L   +    DL S      ++   GC A   V  C D C    
Sbjct: 681  RTLQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLNLIANLSGCTAHRRVNNCSDMCFHQK 740

Query: 138  YRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSN 197
            YRT  G CNN + P  GA+  A  R L + YE+G + P G  P +  NG  LP+ R VS 
Sbjct: 741  YRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVST 800

Query: 198  KIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQ-CDEYCIQGDNC 256
             ++G   E    D+  + + MQWGQ +DHDLD +    L  + +S  Q C   C     C
Sbjct: 801  TLIG--TETVTPDEQFTHMLMQWGQFLDHDLD-STVVALSQARFSDGQHCSNVCSNDPPC 857

Query: 257  FPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLA-----REQINALTSFLDASFVYS 311
            F +M PPND +A +  +CM F R+  VC +     L      REQIN LTS++DAS VY 
Sbjct: 858  FSVMIPPNDSRARSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYG 917

Query: 312  SEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDS 371
            S    A  +R+L+S  GL+     V   G P LP+ +  P+ C      + +PCFLAGD 
Sbjct: 918  STEHEARSIRDLASHRGLLRQGI-VQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDH 976

Query: 372  RASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLP 431
            RA+E + L + HTL+ REHNR+A EL +LNP WDG+ +Y E RKI+GA +Q IT++ +LP
Sbjct: 977  RANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLP 1036

Query: 432  ILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWGPEPE 490
             +LG+   + +  Y GY   ++  I N F T AFRFGH  V   ++RLDEN+QP   +  
Sbjct: 1037 KILGEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQD-H 1095

Query: 491  LPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDL 550
            LPLH  FF+ +R+V +GGIDPL+RGL     K+   ++++  EL  +LF   H +   DL
Sbjct: 1096 LPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTV-ALDL 1154

Query: 551  AAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIW 610
            AAIN QR RDHG P Y+ +R +C+LS   T E+L   +K+  + +KL  LYG+  NID++
Sbjct: 1155 AAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLF 1214

Query: 611  IGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLV 670
               + E LV   R+GP L CLL  QF+++RDGDR W+ENPGVF+  Q   +++ S +R++
Sbjct: 1215 PALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLARIL 1274

Query: 671  CDNT-RITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
            CDN   IT+V  D F    +P+ +  C  I ++DL  W
Sbjct: 1275 CDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVW 1312


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score =  398 bits (1022), Expect = e-110
 Identities = 250/646 (38%), Positives = 349/646 (54%), Gaps = 34/646 (5%)

Query: 86   RNGQVWEESLKRLRQKASLTNVTDPS---------LDLTSLSLEV---GCGAPAPVVRC- 132
            R G+++E +L+ +R++       D           +   SLSL     GC A  P+  C 
Sbjct: 660  RAGEIFEHTLQLIRERVKQGLTVDLEGKEFRYNDLVSPRSLSLIANLSGCTARRPLPNCS 719

Query: 133  DPC--SPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGW-TPGKTRNGFPL 189
            + C  + YR   G CNN ++P  GAA  A AR L   Y DG+  P G   P  +R   PL
Sbjct: 720  NRCFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVGSRQ--PL 777

Query: 190  PLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQ-CDE 248
            P  R V+   V         D + + + M WG  ++HDLD      L ++ +S  + C  
Sbjct: 778  PPPRLVAT--VWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPA-LSTARFSDGRPCSS 834

Query: 249  YCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVC----PTPPYKSL-AREQINALTSF 303
             C     CFP+     DP+ GT   CM F R+   C    P+    S+ AREQIN  T++
Sbjct: 835  VCTNDPPCFPMNTRHADPR-GTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQTAY 893

Query: 304  LDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARV 363
            +D S VY S    +  LR+ S P GL+         G P LP+ +  P+ C         
Sbjct: 894  IDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECA--RQEQES 951

Query: 364  PCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQI 423
            PCFLAGD RA+EH+ LA  HTL+ REHNR+A EL  LNP W+G  +YQEARKI+GA +Q 
Sbjct: 952  PCFLAGDHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVGAELQH 1011

Query: 424  ITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENY 482
            IT+  +LP +LGD   + +  Y+GY+ +V+  I N F T AFRFGH  +   ++RL+   
Sbjct: 1012 ITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATL 1071

Query: 483  QPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPT 542
                 E  LP H   F+  R++K+GGIDP++RGL    +K    + +++ EL  +LF   
Sbjct: 1072 GEIS-EGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAA 1130

Query: 543  HRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYG 602
            +     D AA   QR RDHG P Y  +R FC+L+  +  E+L   +K   + +KL  LYG
Sbjct: 1131 YSA-AVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYG 1189

Query: 603  TPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQ 662
            +P +ID+W   + E L+   RVGP L CL   QFQ++RDGDRFW+ENPGVFT  Q   L+
Sbjct: 1190 SPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLK 1249

Query: 663  KMSFSRLVCDN-TRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
            + S SR++CDN   I +V  D F    YP D+++CS I K+DL  W
Sbjct: 1250 QASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVW 1295


>gi|28558990 thyroid peroxidase isoform e [Homo sapiens]
          Length = 760

 Score =  291 bits (744), Expect = 2e-78
 Identities = 139/289 (48%), Positives = 195/289 (67%), Gaps = 3/289 (1%)

Query: 421 VQIITFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRL 478
           +QIIT RDY+P +LG +  Q+++ PY+GY  + +P +SNVF T AFRFGH  +   + RL
Sbjct: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331

Query: 479 DENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKL 538
           D ++Q     P L LH  FF+ W +++ GG+DPL+RGLLA+ +KL  Q+++M  EL  +L
Sbjct: 332 DASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERL 391

Query: 539 FQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLL 598
           F  ++     DLA+IN QR RDHG PGYN WR FC L + +T  +L+T + S+ +A K+L
Sbjct: 392 FVLSNS-STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKIL 450

Query: 599 GLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQK 658
            LY  PDNID+W+G +AE  + R R GPL ACL+GKQ + +RDGD FWWEN  VFT+ Q+
Sbjct: 451 DLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQR 510

Query: 659 DSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
             L+K S SR++CDNT +T+VP D F    +P DF  C +I  ++L  W
Sbjct: 511 RELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 559



 Score =  128 bits (321), Expect = 2e-29
 Identities = 85/238 (35%), Positives = 119/238 (50%), Gaps = 12/238 (5%)

Query: 32  SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91
           S +S  + ++K  V+ A   +  R        +P   QL  + K  +  +    R  ++ 
Sbjct: 37  SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94

Query: 92  EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141
           E S++ +++K +L      + TD  S DL S+   + GC       +C + C  + YR I
Sbjct: 95  ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154

Query: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201
           TG CNNR  P  GA+N ALARWLP  YEDG S P GW PG   NGFPLP  REV+  ++ 
Sbjct: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214

Query: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPI 259
             NE    D   S L M WGQ +DHD+ F P +   ++    A C   C   + CFPI
Sbjct: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPI 272


>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score =  121 bits (304), Expect = 2e-27
 Identities = 148/565 (26%), Positives = 245/565 (43%), Gaps = 71/565 (12%)

Query: 124 GAPAPVVRCDPCS-PYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGK 182
           GA  P+   +P S   +   G  NN  +   G+    L R +PA Y DG+  P G     
Sbjct: 14  GAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH-- 71

Query: 183 TRNGFPLPLAREVSNKIVGYLNEEGVLD-QNRSLLFMQWGQIVDHDLDFAPDTELGSSEY 241
                 LP  R++SN I       G+   +NR++L + +G  V  DL  + +T    +E+
Sbjct: 72  ------LPNPRDLSNTISR--GPAGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPAEF 122

Query: 242 SKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK---CMPFFRAGFVCPTPPYKSLAREQIN 298
                            I  PP DP      +    +PF R+ +   T    S  R+  N
Sbjct: 123 LN---------------IRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPAN 167

Query: 299 ALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKP-----SP 353
            +T +LD S +Y S  S +  LR+ S   G +A   +      P  P DS+ P     +P
Sbjct: 168 QVTGWLDGSAIYGSSHSWSDALRSFSR--GQLASGPD------PAFPRDSQNPLLMWAAP 219

Query: 354 CEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEA 413
                       +  G  R +    L     L+ R HN  A+ L R +P W+ E+L+Q A
Sbjct: 220 DPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHA 279

Query: 414 RKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAF-RFGHLEVP 472
           RK + A  Q I   ++LP  L    QK +P Y GY   +DP IS+ F  A  +F    VP
Sbjct: 280 RKRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVP 335

Query: 473 SSMFRLDENYQPWG---PEPELPLHTLFFNTW------RMVKDGGIDPLVRGLLAKKSKL 523
             ++  + +    G       +       N++       +     +D L+ G+ ++ ++ 
Sbjct: 336 PGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE- 394

Query: 524 MKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEE 583
            +++ ++  ++R+    P  +    D  A   QR RD G P Y   RA   LS     ++
Sbjct: 395 -REDHVLVEDVRDFWPGPL-KFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQD 452

Query: 584 LNTVL--KSKMLAKKLLGLYGTPDNIDI-WIGAIAEPLVERGR-VGPLLACLLGKQFQQI 639
           +N  L   +  + +    LY    N D+ W+  +   L+E  R  GPL + ++ +QF ++
Sbjct: 453 INPALSRSNDTVLEATAALY----NQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRL 508

Query: 640 RDGDRFWWENP--GVFTNEQKDSLQ 662
           RDGDR+W+EN   G+F+ ++ + ++
Sbjct: 509 RDGDRYWFENTRNGLFSKKEIEEIR 533


>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score =  121 bits (304), Expect = 2e-27
 Identities = 148/565 (26%), Positives = 245/565 (43%), Gaps = 71/565 (12%)

Query: 124 GAPAPVVRCDPCS-PYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGK 182
           GA  P+   +P S   +   G  NN  +   G+    L R +PA Y DG+  P G     
Sbjct: 14  GAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH-- 71

Query: 183 TRNGFPLPLAREVSNKIVGYLNEEGVLD-QNRSLLFMQWGQIVDHDLDFAPDTELGSSEY 241
                 LP  R++SN I       G+   +NR++L + +G  V  DL  + +T    +E+
Sbjct: 72  ------LPNPRDLSNTISR--GPAGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPAEF 122

Query: 242 SKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK---CMPFFRAGFVCPTPPYKSLAREQIN 298
                            I  PP DP      +    +PF R+ +   T    S  R+  N
Sbjct: 123 LN---------------IRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPAN 167

Query: 299 ALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKP-----SP 353
            +T +LD S +Y S  S +  LR+ S   G +A   +      P  P DS+ P     +P
Sbjct: 168 QVTGWLDGSAIYGSSHSWSDALRSFSR--GQLASGPD------PAFPRDSQNPLLMWAAP 219

Query: 354 CEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEA 413
                       +  G  R +    L     L+ R HN  A+ L R +P W+ E+L+Q A
Sbjct: 220 DPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHA 279

Query: 414 RKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAF-RFGHLEVP 472
           RK + A  Q I   ++LP  L    QK +P Y GY   +DP IS+ F  A  +F    VP
Sbjct: 280 RKRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVP 335

Query: 473 SSMFRLDENYQPWG---PEPELPLHTLFFNTW------RMVKDGGIDPLVRGLLAKKSKL 523
             ++  + +    G       +       N++       +     +D L+ G+ ++ ++ 
Sbjct: 336 PGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE- 394

Query: 524 MKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEE 583
            +++ ++  ++R+    P  +    D  A   QR RD G P Y   RA   LS     ++
Sbjct: 395 -REDHVLVEDVRDFWPGPL-KFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQD 452

Query: 584 LNTVL--KSKMLAKKLLGLYGTPDNIDI-WIGAIAEPLVERGR-VGPLLACLLGKQFQQI 639
           +N  L   +  + +    LY    N D+ W+  +   L+E  R  GPL + ++ +QF ++
Sbjct: 453 INPALSRSNDTVLEATAALY----NQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRL 508

Query: 640 RDGDRFWWENP--GVFTNEQKDSLQ 662
           RDGDR+W+EN   G+F+ ++ + ++
Sbjct: 509 RDGDRYWFENTRNGLFSKKEIEEIR 533


>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
          Length = 1548

 Score =  117 bits (294), Expect = 3e-26
 Identities = 153/588 (26%), Positives = 245/588 (41%), Gaps = 92/588 (15%)

Query: 102 ASLTNVTDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALA 161
           A LT    PS +  +LSL      P  V R D         G  NN R    GA    L 
Sbjct: 14  ALLTGSLGPSGNQDALSL------PWEVQRYD---------GWFNNLRHHERGAVGCRLQ 58

Query: 162 RWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWG 221
           R +PA Y DG+         +      LP  R +SN     +     L  NR++L + +G
Sbjct: 59  RRVPANYADGVY--------QALEEPQLPNPRRLSNAATRGIAGLPSL-HNRTVLGVFFG 109

Query: 222 QIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK---CMPFF 278
             V  D+  + +T    +E+                 I  PP DP      +    +PF 
Sbjct: 110 YHVLSDV-VSVETPGCPAEFLN---------------IRIPPGDPVFDPDQRGDVVLPFQ 153

Query: 279 RAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSD 338
           R+ +   T    S  R+  N +T +LD S +Y S  S +  LR+ S   G +A   +   
Sbjct: 154 RSRWDPETGRSPSNPRDLANQVTGWLDGSAIYGSSHSWSDALRSFSG--GQLASGPD--- 208

Query: 339 HGLPYLPYDSKKP-----SPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRL 393
              P  P DS+ P     +P            +  G  R +    L     L+ R HN  
Sbjct: 209 ---PAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLW 265

Query: 394 ARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVD 453
           A+ L R +P W+ E+L+Q ARK + A  Q I   ++LP  L    QK +P Y GY   +D
Sbjct: 266 AQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLD 321

Query: 454 PRISNVFTFAF-RFGHLEVPSSMFR----------LDENYQPWGPEPELPLHTLFFNTW- 501
           P IS  F  A  +F    VP  ++           L++ +Q            +  N W 
Sbjct: 322 PSISPEFVVASEQFFSTMVPPGVYMRNASCHFRKVLNKGFQ------SSQALRVCNNYWI 375

Query: 502 ----RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQR 557
                +     ++ L+ G+ ++ S+L  ++ ++  +LR+    P  +    D  A + QR
Sbjct: 376 RENPNLNSTQEVNELLLGMASQISEL--EDNIVVEDLRDYWPGP-GKFSRTDYVASSIQR 432

Query: 558 CRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTP-DNIDIWIGAIAE 616
            RD G P Y+       L  P+   +LN  +  ++L +    LY      +++ +G + E
Sbjct: 433 GRDMGLPSYSQALLAFGLDIPRNWSDLNPNVDPQVL-EATAALYNQDLSQLELLLGGLLE 491

Query: 617 PLVERGRVGPLLACLLGKQFQQIRDGDRFWWENP--GVFTNEQKDSLQ 662
                G  GPL + ++  QF ++RDGDR+W+EN   G+F+ ++ + ++
Sbjct: 492 ---SHGDPGPLFSAIVLDQFVRLRDGDRYWFENTRNGLFSKKEIEDIR 536


>gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1
           precursor [Homo sapiens]
          Length = 599

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 75/305 (24%), Positives = 120/305 (39%), Gaps = 47/305 (15%)

Query: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 443
           TL+LREHNR+   LK  +P W  E+L+Q  R IL      I   +Y+  L G  +Q    
Sbjct: 302 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD 361

Query: 444 P--YQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTW 501
           P    G       RI+  F   + + H  +P S F++           E       FNT 
Sbjct: 362 PELLFGVQFQYRNRIAMEFNHLYHW-HPLMPDS-FKVGSQ--------EYSYEQFLFNT- 410

Query: 502 RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDH 561
            M+ D G++ LV             ++ + G +        H +H   +A    +  R+ 
Sbjct: 411 SMLVDYGVEALVDAF----------SRQIAGRIGGGRNMDHHILH---VAVDVIRESREM 457

Query: 562 GQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAI------- 614
               +N +R    +    + +EL   +  K +A +L  LYG  D ++ + G +       
Sbjct: 458 RLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPN 514

Query: 615 ---AEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQK-MSFSRLV 670
               E ++E G    L   LLG           +W   P  F  E   ++ K  +  +LV
Sbjct: 515 SIFGESMIEIGAPFSLKG-LLGNPI----CSPEYW--KPSTFGGEVGFNIVKTATLKKLV 567

Query: 671 CDNTR 675
           C NT+
Sbjct: 568 CLNTK 572


>gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo
           sapiens]
          Length = 604

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 24/61 (39%), Positives = 35/61 (57%)

Query: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 443
           T++LREHNR+   LK+ +P+W  E+L+Q +R IL      I   DY+  L G H +    
Sbjct: 289 TIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFD 348

Query: 444 P 444
           P
Sbjct: 349 P 349


>gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2
           precursor [Homo sapiens]
          Length = 562

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/61 (39%), Positives = 32/61 (52%)

Query: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 443
           TL+LREHNR+   LK  +P W  E+L+Q  R IL      I   +Y+  L G  +Q    
Sbjct: 302 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD 361

Query: 444 P 444
           P
Sbjct: 362 P 362


>gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo
           sapiens]
          Length = 439

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 1/90 (1%)

Query: 12  ASLILLQAAASTTRAQTTRTSAISDTVSQAKVQV-NKAFLDSRTRLKTAMSSETPTSRQL 70
           +S  L++AAA    ++ TRT    D  S   V++  +A LD+R  +    S+ T +S   
Sbjct: 252 SSTFLMKAAAKVVESKRTRTITSQDKPSGNDVEMETEANLDTRKSVSDKQSAVTESSEGT 311

Query: 71  SEYLKHAKGRTRTAIRNGQVWEESLKRLRQ 100
              L+  K    + +++G   ++  K+ R+
Sbjct: 312 VSLLRSHKNLFLSKLQHGTQQQDLNKKERR 341


>gi|33469919 minichromosome maintenance complex component 4 [Homo
           sapiens]
          Length = 863

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 6/96 (6%)

Query: 26  AQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAI 85
           A +T    +S+  SQA ++   A++D R ++ ++    +   RQL   ++ A+   +  +
Sbjct: 694 AHSTIMPRLSEEASQALIE---AYVDMR-KIGSSRGMVSAYPRQLESLIRLAEAHAKVRL 749

Query: 86  RNG--QVWEESLKRLRQKASLTNVTDPSLDLTSLSL 119
            N    +  E  KRL ++A   + TDP   +  +S+
Sbjct: 750 SNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISI 785


>gi|33469917 minichromosome maintenance complex component 4 [Homo
           sapiens]
          Length = 863

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 6/96 (6%)

Query: 26  AQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAI 85
           A +T    +S+  SQA ++   A++D R ++ ++    +   RQL   ++ A+   +  +
Sbjct: 694 AHSTIMPRLSEEASQALIE---AYVDMR-KIGSSRGMVSAYPRQLESLIRLAEAHAKVRL 749

Query: 86  RNG--QVWEESLKRLRQKASLTNVTDPSLDLTSLSL 119
            N    +  E  KRL ++A   + TDP   +  +S+
Sbjct: 750 SNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISI 785


>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
           sapiens]
          Length = 1367

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 27/114 (23%), Positives = 41/114 (35%), Gaps = 4/114 (3%)

Query: 71  SEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPS---LDLTSLSLEVGCGAPA 127
           S ++   + + R  ++       S  R    A   N+TDP     +       V      
Sbjct: 729 SIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERT 788

Query: 128 PVVRCDPCSPYRTITGDCNNR-RKPALGAANRALARWLPAEYEDGLSLPFGWTP 180
            +    P + YR     CN+   K    A+N   AR +PAE  D +  P  W P
Sbjct: 789 VISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEP 842


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 16/59 (27%), Positives = 29/59 (49%)

Query: 42  KVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQ 100
           +VQ N    DS   LK A+ ++    + L + L   +  TR+ ++   ++   LK LR+
Sbjct: 554 QVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELRE 612


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 16/59 (27%), Positives = 29/59 (49%)

Query: 42  KVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQ 100
           +VQ N    DS   LK A+ ++    + L + L   +  TR+ ++   ++   LK LR+
Sbjct: 554 QVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELRE 612


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,212,977
Number of Sequences: 37866
Number of extensions: 1303301
Number of successful extensions: 3055
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2971
Number of HSP's gapped (non-prelim): 32
length of query: 712
length of database: 18,247,518
effective HSP length: 109
effective length of query: 603
effective length of database: 14,120,124
effective search space: 8514434772
effective search space used: 8514434772
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press