BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|40549413 glial cell derived neurotrophic factor isoform 3 [Homo sapiens] (133 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|40549413 glial cell derived neurotrophic factor isoform 3 [Ho... 281 8e-77 gi|40549411 glial cell derived neurotrophic factor isoform 2 pre... 241 1e-64 gi|4503975 glial cell derived neurotrophic factor isoform 1 prep... 241 1e-64 gi|4758826 neurturin preproprotein [Homo sapiens] 100 4e-22 gi|16950645 neurotrophic factor artemin isoform 2 [Homo sapiens] 70 6e-13 gi|209954781 neurotrophic factor artemin isoform 1 precursor [Ho... 70 6e-13 gi|209954778 neurotrophic factor artemin isoform 3 precursor [Ho... 70 6e-13 gi|209954776 neurotrophic factor artemin isoform 1 precursor [Ho... 70 6e-13 gi|209977029 neurotrophic factor artemin isoform 3 precursor [Ho... 70 6e-13 gi|4758974 persephin precursor [Homo sapiens] 68 2e-12 gi|7705308 growth differentiation factor 2 [Homo sapiens] 32 0.11 gi|4503969 growth differentiation factor 5 preproprotein [Homo s... 31 0.25 gi|126507087 bone morphogenetic protein 3 preproprotein [Homo sa... 29 0.97 gi|56237021 fibrillin 3 precursor [Homo sapiens] 28 2.8 gi|24234690 meiotic recombination 11 homolog A isoform 2 [Homo s... 27 4.8 gi|5031923 meiotic recombination 11 homolog A isoform 1 [Homo sa... 27 4.8 gi|21361870 chromosome 11 open reading frame 17 [Homo sapiens] 27 4.8 gi|116174740 chromosome 11 open reading frame 17 [Homo sapiens] 27 4.8 gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 26 8.2 >gi|40549413 glial cell derived neurotrophic factor isoform 3 [Homo sapiens] Length = 133 Score = 281 bits (720), Expect = 8e-77 Identities = 133/133 (100%), Positives = 133/133 (100%) Query: 1 MGCRGCLPGAAPHRVRLPAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKE 60 MGCRGCLPGAAPHRVRLPAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKE Sbjct: 1 MGCRGCLPGAAPHRVRLPAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKE 60 Query: 61 ELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYH 120 ELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYH Sbjct: 61 ELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYH 120 Query: 121 ILRKHSAKRCGCI 133 ILRKHSAKRCGCI Sbjct: 121 ILRKHSAKRCGCI 133 >gi|40549411 glial cell derived neurotrophic factor isoform 2 precursor [Homo sapiens] Length = 185 Score = 241 bits (615), Expect = 1e-64 Identities = 115/115 (100%), Positives = 115/115 (100%) Query: 19 AANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTY 78 AANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTY Sbjct: 71 AANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTY 130 Query: 79 DKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI 133 DKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI Sbjct: 131 DKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI 185 >gi|4503975 glial cell derived neurotrophic factor isoform 1 preproprotein [Homo sapiens] Length = 211 Score = 241 bits (615), Expect = 1e-64 Identities = 115/115 (100%), Positives = 115/115 (100%) Query: 19 AANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTY 78 AANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTY Sbjct: 97 AANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTY 156 Query: 79 DKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI 133 DKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI Sbjct: 157 DKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI 211 >gi|4758826 neurturin preproprotein [Homo sapiens] Length = 197 Score = 100 bits (248), Expect = 4e-22 Identities = 48/115 (41%), Positives = 72/115 (62%), Gaps = 5/115 (4%) Query: 20 ANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYD 79 A P R + R G R C L + + V++LGLGY + E ++FRYC+G+C+AA YD Sbjct: 87 AGPRRRRARARLGARP----CGLRELEVRVSELGLGYASDETVLFRYCAGACEAAARVYD 142 Query: 80 KILKNLSRNRRLVSDKV-GQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI 133 L+ L + RRL ++V Q CCRP A++D++SFLD + YH + + SA+ C C+ Sbjct: 143 LGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVSFLDAHSRYHTVHELSARECACV 197 >gi|16950645 neurotrophic factor artemin isoform 2 [Homo sapiens] Length = 237 Score = 69.7 bits (169), Expect = 6e-13 Identities = 47/132 (35%), Positives = 66/132 (50%), Gaps = 10/132 (7%) Query: 11 APHRVRLPAANPENSR-----GKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFR 65 AP P+A P R G G R + RGC L + + V LGLG+ + E + FR Sbjct: 106 APPPPAPPSALPRGGRAARAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFR 165 Query: 66 YCSGSCDAAETTYDKILKNLSRNRRL----VSDKVGQACCRPIAFDDDLSFLDDNLVYHI 121 +CSGSC A + +D L +L L S V Q CCRP + + +SF+D N + Sbjct: 166 FCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRY-EAVSFMDVNSTWRT 224 Query: 122 LRKHSAKRCGCI 133 + + SA CGC+ Sbjct: 225 VDRLSATACGCL 236 >gi|209954781 neurotrophic factor artemin isoform 1 precursor [Homo sapiens] Length = 220 Score = 69.7 bits (169), Expect = 6e-13 Identities = 47/132 (35%), Positives = 66/132 (50%), Gaps = 10/132 (7%) Query: 11 APHRVRLPAANPENSR-----GKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFR 65 AP P+A P R G G R + RGC L + + V LGLG+ + E + FR Sbjct: 89 APPPPAPPSALPRGGRAARAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFR 148 Query: 66 YCSGSCDAAETTYDKILKNLSRNRRL----VSDKVGQACCRPIAFDDDLSFLDDNLVYHI 121 +CSGSC A + +D L +L L S V Q CCRP + + +SF+D N + Sbjct: 149 FCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRY-EAVSFMDVNSTWRT 207 Query: 122 LRKHSAKRCGCI 133 + + SA CGC+ Sbjct: 208 VDRLSATACGCL 219 >gi|209954778 neurotrophic factor artemin isoform 3 precursor [Homo sapiens] Length = 228 Score = 69.7 bits (169), Expect = 6e-13 Identities = 47/132 (35%), Positives = 66/132 (50%), Gaps = 10/132 (7%) Query: 11 APHRVRLPAANPENSR-----GKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFR 65 AP P+A P R G G R + RGC L + + V LGLG+ + E + FR Sbjct: 97 APPPPAPPSALPRGGRAARAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFR 156 Query: 66 YCSGSCDAAETTYDKILKNLSRNRRL----VSDKVGQACCRPIAFDDDLSFLDDNLVYHI 121 +CSGSC A + +D L +L L S V Q CCRP + + +SF+D N + Sbjct: 157 FCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRY-EAVSFMDVNSTWRT 215 Query: 122 LRKHSAKRCGCI 133 + + SA CGC+ Sbjct: 216 VDRLSATACGCL 227 >gi|209954776 neurotrophic factor artemin isoform 1 precursor [Homo sapiens] Length = 220 Score = 69.7 bits (169), Expect = 6e-13 Identities = 47/132 (35%), Positives = 66/132 (50%), Gaps = 10/132 (7%) Query: 11 APHRVRLPAANPENSR-----GKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFR 65 AP P+A P R G G R + RGC L + + V LGLG+ + E + FR Sbjct: 89 APPPPAPPSALPRGGRAARAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFR 148 Query: 66 YCSGSCDAAETTYDKILKNLSRNRRL----VSDKVGQACCRPIAFDDDLSFLDDNLVYHI 121 +CSGSC A + +D L +L L S V Q CCRP + + +SF+D N + Sbjct: 149 FCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRY-EAVSFMDVNSTWRT 207 Query: 122 LRKHSAKRCGCI 133 + + SA CGC+ Sbjct: 208 VDRLSATACGCL 219 >gi|209977029 neurotrophic factor artemin isoform 3 precursor [Homo sapiens] Length = 228 Score = 69.7 bits (169), Expect = 6e-13 Identities = 47/132 (35%), Positives = 66/132 (50%), Gaps = 10/132 (7%) Query: 11 APHRVRLPAANPENSR-----GKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFR 65 AP P+A P R G G R + RGC L + + V LGLG+ + E + FR Sbjct: 97 APPPPAPPSALPRGGRAARAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFR 156 Query: 66 YCSGSCDAAETTYDKILKNLSRNRRL----VSDKVGQACCRPIAFDDDLSFLDDNLVYHI 121 +CSGSC A + +D L +L L S V Q CCRP + + +SF+D N + Sbjct: 157 FCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRY-EAVSFMDVNSTWRT 215 Query: 122 LRKHSAKRCGCI 133 + + SA CGC+ Sbjct: 216 VDRLSATACGCL 227 >gi|4758974 persephin precursor [Homo sapiens] Length = 156 Score = 68.2 bits (165), Expect = 2e-12 Identities = 41/103 (39%), Positives = 58/103 (56%), Gaps = 6/103 (5%) Query: 31 RGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCD-AAETTYDKILKNLSRNR 89 R +R + C L ++ L+V +LGLGY ++E++IFRYC+GSC A T + L L Sbjct: 57 RLRRALSGPCQLWSLTLSVAELGLGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQG 116 Query: 90 RLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGC 132 R G CCRP + D++FLDD + L + SA CGC Sbjct: 117 R----AHGGPCCRPTRY-TDVAFLDDRHRWQRLPQLSAAACGC 154 >gi|7705308 growth differentiation factor 2 [Homo sapiens] Length = 429 Score = 32.3 bits (72), Expect = 0.11 Identities = 31/120 (25%), Positives = 43/120 (35%), Gaps = 25/120 (20%) Query: 30 RRGQRGKNRGCVLTAIHLNVTDLGLG--------YETKEELIFRYCSGSC-----DAAET 76 R+ G C T++ +N D+G YE E C G C D Sbjct: 317 RKRSAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYE------CKGGCFFPLADDVTP 370 Query: 77 TYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKH----SAKRCGC 132 T I++ L + KVG+ACC P D++ L+ H S CGC Sbjct: 371 TKHAIVQTLVHLK--FPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGC 428 >gi|4503969 growth differentiation factor 5 preproprotein [Homo sapiens] Length = 501 Score = 31.2 bits (69), Expect = 0.25 Identities = 26/115 (22%), Positives = 46/115 (40%), Gaps = 12/115 (10%) Query: 28 KGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFR--YCSGSCD-----AAETTYDK 80 +G+R + C A+H+N D+G L + +C G C+ E T Sbjct: 388 QGKRPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHA 447 Query: 81 ILKNLSRNRRLVSDKVGQACCRPIAFDD-DLSFLD--DNLVYHILRKHSAKRCGC 132 +++ L + + + CC P + F+D +N+VY + CGC Sbjct: 448 VIQTLMNS--MDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGC 500 >gi|126507087 bone morphogenetic protein 3 preproprotein [Homo sapiens] Length = 472 Score = 29.3 bits (64), Expect = 0.97 Identities = 28/131 (21%), Positives = 53/131 (40%), Gaps = 11/131 (8%) Query: 12 PHRVRLPAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLG--YETKEELIFRYCSG 69 PHR E + K RR Q + R C + ++ D+G + + YCSG Sbjct: 342 PHRKSQTLQFDEQTLKKARRKQWIEPRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSG 401 Query: 70 SCD-----AAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDD-DLSFLDD--NLVYHI 121 +C + + + ++++ R +V + + CC P + F D+ N+V + Sbjct: 402 ACQFPMPKSLKPSNHATIQSIVRAVGVVPG-IPEPCCVPEKMSSLSILFFDENKNVVLKV 460 Query: 122 LRKHSAKRCGC 132 + + C C Sbjct: 461 YPNMTVESCAC 471 >gi|56237021 fibrillin 3 precursor [Homo sapiens] Length = 2809 Score = 27.7 bits (60), Expect = 2.8 Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 6/67 (8%) Query: 37 NRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKV 96 N CV A +L V + ++ + FR+ +G+C +++ N++R S + Sbjct: 1627 NYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQ------NELAFNVTRKMCCCSYNI 1680 Query: 97 GQACCRP 103 GQA RP Sbjct: 1681 GQAWNRP 1687 >gi|24234690 meiotic recombination 11 homolog A isoform 2 [Homo sapiens] Length = 680 Score = 26.9 bits (58), Expect = 4.8 Identities = 11/19 (57%), Positives = 13/19 (68%) Query: 19 AANPENSRGKGRRGQRGKN 37 A N RG+GRRG RG+N Sbjct: 565 ATNKGRGRGRGRRGGRGQN 583 >gi|5031923 meiotic recombination 11 homolog A isoform 1 [Homo sapiens] Length = 708 Score = 26.9 bits (58), Expect = 4.8 Identities = 11/19 (57%), Positives = 13/19 (68%) Query: 19 AANPENSRGKGRRGQRGKN 37 A N RG+GRRG RG+N Sbjct: 565 ATNKGRGRGRGRRGGRGQN 583 >gi|21361870 chromosome 11 open reading frame 17 [Homo sapiens] Length = 210 Score = 26.9 bits (58), Expect = 4.8 Identities = 11/22 (50%), Positives = 13/22 (59%) Query: 2 GCRGCLPGAAPHRVRLPAANPE 23 GC G L APH + PAA P+ Sbjct: 47 GCMGVLAREAPHLEKQPAAGPQ 68 >gi|116174740 chromosome 11 open reading frame 17 [Homo sapiens] Length = 210 Score = 26.9 bits (58), Expect = 4.8 Identities = 11/22 (50%), Positives = 13/22 (59%) Query: 2 GCRGCLPGAAPHRVRLPAANPE 23 GC G L APH + PAA P+ Sbjct: 47 GCMGVLAREAPHLEKQPAAGPQ 68 >gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] Length = 2017 Score = 26.2 bits (56), Expect = 8.2 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 11/59 (18%) Query: 16 RLPAANPENSRGKGRRGQRGKNRGC----VLTAIH-------LNVTDLGLGYETKEELI 63 R P+ +S G+GR +RG + C L IH L V D+ YE ++L+ Sbjct: 491 RTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLL 549 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.140 0.446 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,390,295 Number of Sequences: 37866 Number of extensions: 224344 Number of successful extensions: 679 Number of sequences better than 10.0: 19 Number of HSP's better than 10.0 without gapping: 14 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 653 Number of HSP's gapped (non-prelim): 19 length of query: 133 length of database: 18,247,518 effective HSP length: 91 effective length of query: 42 effective length of database: 14,801,712 effective search space: 621671904 effective search space used: 621671904 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.