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Search of human proteins with 40548422
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40548422 chromatin modifying protein 4A [Homo sapiens]
(265 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40548422 chromatin modifying protein 4A [Homo sapiens] 521 e-148
gi|28827795 chromatin modifying protein 4B [Homo sapiens] 271 4e-73
gi|22748643 chromatin modifying protein 4C [Homo sapiens] 244 4e-65
gi|31542673 chromatin modifying protein 6 [Homo sapiens] 84 1e-16
gi|189409150 chromatin modifying protein 5 [Homo sapiens] 78 7e-15
gi|22748641 CHMP family, member 7 [Homo sapiens] 60 2e-09
gi|4504063 golgin 97 [Homo sapiens] 47 1e-05
gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens] 45 7e-05
gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens] 45 7e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 45 7e-05
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 45 9e-05
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 45 9e-05
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo... 45 9e-05
gi|16262452 cingulin [Homo sapiens] 44 1e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 44 1e-04
gi|31982906 cingulin-like 1 [Homo sapiens] 44 2e-04
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 41 0.001
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 41 0.001
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 41 0.001
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 41 0.001
gi|40254866 chromatin modifying protein 2B [Homo sapiens] 41 0.001
gi|4505257 moesin [Homo sapiens] 41 0.001
gi|32698688 citron [Homo sapiens] 40 0.002
gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan... 40 0.002
gi|71284108 nudE nuclear distribution gene E homolog (A. nidulan... 40 0.002
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 40 0.002
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 40 0.002
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 40 0.002
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 40 0.002
gi|50980301 myosin phosphatase-Rho interacting protein isoform 2... 40 0.002
>gi|40548422 chromatin modifying protein 4A [Homo sapiens]
Length = 265
Score = 521 bits (1342), Expect = e-148
Identities = 265/265 (100%), Positives = 265/265 (100%)
Query: 1 MSRRRPEDGLGKAGPCVMRHHPPRSKAEVWRTLRGGGGRGELAMSGLGRLFGKGKKEKGP 60
MSRRRPEDGLGKAGPCVMRHHPPRSKAEVWRTLRGGGGRGELAMSGLGRLFGKGKKEKGP
Sbjct: 1 MSRRRPEDGLGKAGPCVMRHHPPRSKAEVWRTLRGGGGRGELAMSGLGRLFGKGKKEKGP 60
Query: 61 TPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLA 120
TPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLA
Sbjct: 61 TPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLA 120
Query: 121 QTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQE 180
QTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQE
Sbjct: 121 QTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQE 180
Query: 181 VAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEPSVKLPSVPST 240
VAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEPSVKLPSVPST
Sbjct: 181 VAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEPSVKLPSVPST 240
Query: 241 HLPAGPAPKVDEDEEALKQLAEWVS 265
HLPAGPAPKVDEDEEALKQLAEWVS
Sbjct: 241 HLPAGPAPKVDEDEEALKQLAEWVS 265
>gi|28827795 chromatin modifying protein 4B [Homo sapiens]
Length = 224
Score = 271 bits (693), Expect = 4e-73
Identities = 139/223 (62%), Positives = 180/223 (80%), Gaps = 6/223 (2%)
Query: 44 MSGLGRLFGKGKKEKG---PTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTK 100
MS G+LFG G + G PTP+EAIQ+L++TE++L KKQEFLE+KI+QEL AKK+GTK
Sbjct: 1 MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTK 60
Query: 101 NKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAY 160
NKRAALQAL+RKKR+E+QLAQ DGTLST+EFQREA+ENA TN EVL+ M AA++MK A+
Sbjct: 61 NKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH 120
Query: 161 QDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQEL 220
+MDIDKVDELM DI +QQE+A++IS AIS+P+GFG++ DEDEL+ ELEELEQEEL + L
Sbjct: 121 DNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNL 180
Query: 221 LNVGDKEEEPSVKLPSVPSTHLPAGPAPKVDEDEEALKQLAEW 263
L + E +V LP+VPS LP+ PA K +E+++ +K+L W
Sbjct: 181 LEISGPE---TVPLPNVPSIALPSKPAKKKEEEDDDMKELENW 220
>gi|22748643 chromatin modifying protein 4C [Homo sapiens]
Length = 233
Score = 244 bits (624), Expect = 4e-65
Identities = 126/242 (52%), Positives = 177/242 (73%), Gaps = 29/242 (11%)
Query: 44 MSGLGRLF---GKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTK 100
MS LG+ F G K P+P+EA+ +L+ETE++L KKQE+LE +IQ+E+ AKK+GT+
Sbjct: 1 MSKLGKFFKGGGSSKSRAAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALAKKHGTQ 60
Query: 101 NKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAY 160
NKRAALQAL+RKKRFE+QL Q DGTLST+EFQREA+EN+ TN EVLR M AA++MK +
Sbjct: 61 NKRAALQALKRKKRFEKQLTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVH 120
Query: 161 QDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQEL 220
++MD++K+D+LM +ITEQQ++AQ+IS+A S+ +GFGDD DEDEL+ ELEELEQEEL +++
Sbjct: 121 ENMDLNKIDDLMQEITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEELEQEELNKKM 180
Query: 221 LNVGDKEEEPSVKLPSVPSTHLPAGP-----------------APKVDEDEEALKQLAEW 263
N ++LP+VPS+ LPA P + + +E+++ +KQLA W
Sbjct: 181 TN---------IRLPNVPSSSLPAQPNRKPGMSSTARRSRAASSQRAEEEDDDIKQLAAW 231
Query: 264 VS 265
+
Sbjct: 232 AT 233
>gi|31542673 chromatin modifying protein 6 [Homo sapiens]
Length = 201
Score = 84.3 bits (207), Expect = 1e-16
Identities = 54/207 (26%), Positives = 109/207 (52%), Gaps = 12/207 (5%)
Query: 47 LGRLFGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAAL 106
+G LFG+ K+ + ++AI +LK+ L + Q+ + Q++++E A++ ++
Sbjct: 1 MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERA 60
Query: 107 QALRRKKRFEQQLA-QTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDI 165
+ L +KKR+++QL +T+ +S+LE ++IE +V+ ++ + + K +Q M I
Sbjct: 61 KLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSI 120
Query: 166 DKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGD 225
++V+ ++ + E E +QI + ++ G DED +LEEL + QE++ +
Sbjct: 121 EEVERILDETQEAVEYQRQIDELLA---GSFTQEDEDAILEELSAITQEQI--------E 169
Query: 226 KEEEPSVKLPSVPSTHLPAGPAPKVDE 252
E PS LP ++P P+ E
Sbjct: 170 LPEVPSEPLPEKIPENVPVKARPRQAE 196
>gi|189409150 chromatin modifying protein 5 [Homo sapiens]
Length = 219
Score = 78.2 bits (191), Expect = 7e-15
Identities = 55/182 (30%), Positives = 99/182 (54%), Gaps = 13/182 (7%)
Query: 47 LGRLFGKGK-KEKGPTPEEAIQKLKETEKILIKKQEFLEQ---KIQQELQTAKKYGTKN- 101
+ RLFGK K K P+ + I + + + KK L+ K + +++ ++ KN
Sbjct: 1 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
Query: 102 -KRAALQALRRKKRFEQQ---LAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMK 157
K+ AL+ L++K+ +EQQ LAQ + + +++++ T + M+L + MK
Sbjct: 61 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDA---MKLGVKEMK 117
Query: 158 KAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELA 217
KAY+ + ID++++L + + E A +I +A+SR G ++DED+L EL+ L E LA
Sbjct: 118 KAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYG-TPELDEDDLEAELDALGDELLA 176
Query: 218 QE 219
E
Sbjct: 177 DE 178
>gi|22748641 CHMP family, member 7 [Homo sapiens]
Length = 453
Score = 60.1 bits (144), Expect = 2e-09
Identities = 37/156 (23%), Positives = 84/156 (53%), Gaps = 1/156 (0%)
Query: 66 IQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRA-ALQALRRKKRFEQQLAQTDG 124
+ +L ++E++L +K E L Q+ ++ + A++ K+ AL++L+ K+R E+++
Sbjct: 241 VYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHA 300
Query: 125 TLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQ 184
L T++ + I + T+ V + ++K + +D+ ++K + L+ I E + +
Sbjct: 301 KLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDE 360
Query: 185 ISDAISRPMGFGDDVDEDELLEELEELEQEELAQEL 220
+S ++ + G D D +EL +EL+ L Q+ + L
Sbjct: 361 VSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPL 396
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 47.4 bits (111), Expect = 1e-05
Identities = 39/163 (23%), Positives = 80/163 (49%), Gaps = 10/163 (6%)
Query: 67 QKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTL 126
Q+L + + +L+KK+E L K++QEL+ + ++ + + + + Q+L +
Sbjct: 179 QELSKIKHMLLKKEESLG-KMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHY 237
Query: 127 STLEFQREAIENATTNAE-VLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQI 185
STLE QR+ + + T AE + +E Q ++ Q + ID + ++ + E+++V +
Sbjct: 238 STLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSID-LQKVTAETQEKEDVITHL 296
Query: 186 SDAISR-----PMGFGDDVDEDELLEE--LEELEQEELAQELL 221
+ ++ + ELL+E L E E+ Q+LL
Sbjct: 297 QEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLL 339
>gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]
Length = 335
Score = 45.1 bits (105), Expect = 7e-05
Identities = 46/187 (24%), Positives = 92/187 (49%), Gaps = 23/187 (12%)
Query: 56 KEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRF 115
K++ +E +++ +E + + + LE ++QQ + ++N R ++ K++F
Sbjct: 26 KQRAENTQEELREFQEGSR---EYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKF 82
Query: 116 EQQLAQTDGTLSTLE---FQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELM 172
E Q ++ +S LE Q +AI++ + +R +E A +++A +
Sbjct: 83 EVQHSEGYRQISALEDDLAQTKAIKDQL--QKYIRELEQANDDLERAKR----------- 129
Query: 173 TDITEQQEVAQQISDAISRPMGFGDDVDEDE-LLEELEELEQE--ELAQELLNVGDKEEE 229
I ++ Q+++ AI R ++DE E LLE ++ L+ E +L QEL V K+E+
Sbjct: 130 ATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELA-VQQKQEK 188
Query: 230 PSVKLPS 236
P +PS
Sbjct: 189 PRTPMPS 195
>gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]
Length = 335
Score = 45.1 bits (105), Expect = 7e-05
Identities = 46/187 (24%), Positives = 92/187 (49%), Gaps = 23/187 (12%)
Query: 56 KEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRF 115
K++ +E +++ +E + + + LE ++QQ + ++N R ++ K++F
Sbjct: 26 KQRAENTQEELREFQEGSR---EYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKF 82
Query: 116 EQQLAQTDGTLSTLE---FQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELM 172
E Q ++ +S LE Q +AI++ + +R +E A +++A +
Sbjct: 83 EVQHSEGYRQISALEDDLAQTKAIKDQL--QKYIRELEQANDDLERAKR----------- 129
Query: 173 TDITEQQEVAQQISDAISRPMGFGDDVDEDE-LLEELEELEQE--ELAQELLNVGDKEEE 229
I ++ Q+++ AI R ++DE E LLE ++ L+ E +L QEL V K+E+
Sbjct: 130 ATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELA-VQQKQEK 188
Query: 230 PSVKLPS 236
P +PS
Sbjct: 189 PRTPMPS 195
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 45.1 bits (105), Expect = 7e-05
Identities = 46/210 (21%), Positives = 98/210 (46%), Gaps = 13/210 (6%)
Query: 53 KGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRK 112
+ KK+ +EA ++ ET E +Q++Q E++ + ++ A +++
Sbjct: 1392 EAKKKLAQRLQEA-EENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQ 1450
Query: 113 KRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELM 172
+ F++ LA+ L + + EA + + R++ M+ AY+++ VD+L
Sbjct: 1451 RNFDKVLAEWKQKLDESQAELEAAQKES------RSLSTELFKMRNAYEEV----VDQLE 1500
Query: 173 TDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEEL--AQELLNVGDKEEEP 230
T E + + ++ISD + G ++ E E ++L E E+ +L A E + + EE
Sbjct: 1501 TLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEES 1560
Query: 231 SVKLPSVPSTHLPAGPAPKVDEDEEALKQL 260
+ + + + + KV E +E ++QL
Sbjct: 1561 KILRVQLELSQVKSELDRKVIEKDEEIEQL 1590
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 44.7 bits (104), Expect = 9e-05
Identities = 53/205 (25%), Positives = 88/205 (42%), Gaps = 51/205 (24%)
Query: 63 EEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQT 122
E+ ++LK+ IK QE EQ+ ++ + T K+ TK K AL + ++R QL
Sbjct: 197 EQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLT-- 254
Query: 123 DGTLSTLEFQREAIENATTNAEVLRTM-----------ELAAQSMKKAYQ------DMDI 165
QR+ I+ TTNA+ T E A ++K Q D
Sbjct: 255 --------LQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQ 306
Query: 166 DKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDE--------DELLEELEE------- 210
D + +T+ Q QQ A+SR + D+++E +E L++++E
Sbjct: 307 DTIMAKLTNEDSQNRQLQQKLAALSRQI---DELEETNRSLRKAEEELQDIKEKISKGEY 363
Query: 211 ------LEQEELAQELLNVGDKEEE 229
E EEL + +L++ K+EE
Sbjct: 364 GNAGIMAEVEELRKRVLDMEGKDEE 388
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 44.7 bits (104), Expect = 9e-05
Identities = 53/205 (25%), Positives = 88/205 (42%), Gaps = 51/205 (24%)
Query: 63 EEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQT 122
E+ ++LK+ IK QE EQ+ ++ + T K+ TK K AL + ++R QL
Sbjct: 197 EQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLT-- 254
Query: 123 DGTLSTLEFQREAIENATTNAEVLRTM-----------ELAAQSMKKAYQ------DMDI 165
QR+ I+ TTNA+ T E A ++K Q D
Sbjct: 255 --------LQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQ 306
Query: 166 DKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDE--------DELLEELEE------- 210
D + +T+ Q QQ A+SR + D+++E +E L++++E
Sbjct: 307 DTIMAKLTNEDSQNRQLQQKLAALSRQI---DELEETNRSLRKAEEELQDIKEKISKGEY 363
Query: 211 ------LEQEELAQELLNVGDKEEE 229
E EEL + +L++ K+EE
Sbjct: 364 GNAGIMAEVEELRKRVLDMEGKDEE 388
>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
sapiens]
Length = 805
Score = 44.7 bits (104), Expect = 9e-05
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 33/184 (17%)
Query: 67 QKLKETEKILIKKQEFLEQ----------KIQQELQTAKKYGTKNKRAALQALRRKKRFE 116
QKL TEK +++ EFL+Q K++++L+T +Y + K+ + + K +
Sbjct: 446 QKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQ 505
Query: 117 QQLAQTDGTLSTL---------EFQREAIENATTN-AEVLRTMELAAQSMKKAYQDMDID 166
+++ + L+ L Q + +E N E L E + +KK QD +
Sbjct: 506 RRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQ 565
Query: 167 ------KVDELMTDITE-QQEVAQQISDAISRPMGFGDDVDEDELLEELEEL-EQEELAQ 218
K EL+T + QQ+V + + D I PM +D +L E + L +Q E A
Sbjct: 566 LICQKKKEKELVTTVQSLQQKVERCLEDGIRLPM-----LDAKQLQNENDNLRQQNETAS 620
Query: 219 ELLN 222
++++
Sbjct: 621 KIID 624
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 43.9 bits (102), Expect = 1e-04
Identities = 54/253 (21%), Positives = 113/253 (44%), Gaps = 38/253 (15%)
Query: 31 RTLRGGGGRGELAMSGLGRLFGKGKKEKGPTPEEAIQKL-KETEKILIKKQEFLEQKIQQ 89
R L G + E+ G L +E+ + + +L KE EKI E +Q +QQ
Sbjct: 821 RALEEEGKQREVLRRGKAEL-----EEQKRLLDRTVDRLNKELEKI----GEDSKQALQQ 871
Query: 90 ELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQ----REAIENATTN--- 142
+ Y K +R A R+ K + + +T G LS L+ + R+A++ +
Sbjct: 872 LQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDT 931
Query: 143 --------AEVLRTMELAAQSMKKAYQDMD------IDKVDELMTDITEQQEVAQQISDA 188
A+ L+ +E A++ K++ D +KV L T++ E++ + ++D
Sbjct: 932 ARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDR 991
Query: 189 ISRPMGFGDDVDE--DELLEELEELEQEELAQELLNVGDKEEEPSVKLPSVPSTHLPAGP 246
++R D VD+ EL++ E +++L + +++ + ++ +L S P+
Sbjct: 992 VNRGR---DQVDQLRTELMQ--ERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSAS 1046
Query: 247 APKVDEDEEALKQ 259
+++ + L++
Sbjct: 1047 LSQLESQNQLLQE 1059
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/182 (20%), Positives = 80/182 (43%), Gaps = 14/182 (7%)
Query: 63 EEAIQKLKETEKILIKKQEFLEQKIQ---QELQTAKKYGTKNKRAALQALRRKKRFEQQL 119
+E IQ KE +L ++E L++++ QEL+ K K + LR K +QL
Sbjct: 299 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQL 358
Query: 120 AQTDGTL---------STLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDE 170
Q G + TLE + E I + + + T + K+ + +++++
Sbjct: 359 EQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEK 418
Query: 171 LMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEP 230
++ + +E +++ + + + E+E + +EL + + QE+++V K E
Sbjct: 419 ALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSR--VKQEVVDVMKKSSEE 476
Query: 231 SV 232
+
Sbjct: 477 QI 478
Score = 33.9 bits (76), Expect = 0.15
Identities = 35/196 (17%), Positives = 88/196 (44%), Gaps = 20/196 (10%)
Query: 53 KGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRK 112
K K+E +E ++ +IK+ E Q+ ++ L+ + + L R
Sbjct: 716 KMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKD------QINQLELLLKERD 769
Query: 113 KRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELM 172
K ++ A + + ++ ++ A+ +V ++ + A KAY++ +L+
Sbjct: 770 KHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLL 829
Query: 173 TDITEQQEVAQQISDAISRPMGFGDDVDE-----DELLEELE----ELEQE-----ELAQ 218
TE+ + +Q+++ ++ ++D +L+++LE E+EQ+ ++ +
Sbjct: 830 DLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYE 889
Query: 219 ELLNVGDKEEEPSVKL 234
L G+KE+E + ++
Sbjct: 890 SKLEDGNKEQEQTKQI 905
Score = 32.7 bits (73), Expect = 0.34
Identities = 37/162 (22%), Positives = 75/162 (46%), Gaps = 15/162 (9%)
Query: 57 EKGPTPEEAIQKLKE---TEKILIKKQEFLEQ--KIQQELQTAKKYGTKNKRAALQALRR 111
EK T E+++ ++ TEK+ + KQ++ + K++++ + K+ K+K QA
Sbjct: 610 EKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQA--- 666
Query: 112 KKRFEQQLAQTDGTLSTLEFQREAIENATTN-AEVLRTMELAAQSMKKAYQDMDIDKVDE 170
E+ + TL L+ ++ +E+ ++ +EVL+ + + D K E
Sbjct: 667 --HIEEM---NEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMK-QE 720
Query: 171 LMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELE 212
L + EQ+ QQ D+I + E L +++ +LE
Sbjct: 721 LEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 762
Score = 32.3 bits (72), Expect = 0.44
Identities = 30/123 (24%), Positives = 63/123 (51%), Gaps = 9/123 (7%)
Query: 63 EEAIQKLKET-EKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRK--KRFEQQL 119
EE I KL++ EK L +K EQ++ ++LQT ++ + + AL+ + + K +++
Sbjct: 475 EEQIAKLQKLHEKELARK----EQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKE 530
Query: 120 AQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQ 179
Q L LE Q++AI T + LR ++ A++ + +++ L + + +
Sbjct: 531 QQESLALEELELQKKAI--LTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSK 588
Query: 180 EVA 182
++A
Sbjct: 589 DLA 591
Score = 32.3 bits (72), Expect = 0.44
Identities = 48/242 (19%), Positives = 92/242 (38%), Gaps = 58/242 (23%)
Query: 36 GGGRGELAMSGLGRLFGKGKK---EKGPTPEEAIQKLKETEKILIKKQEFLEQKIQ---- 88
GG A L +F +K EK T + QK+KE + L++++E +++
Sbjct: 1820 GGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTS 1879
Query: 89 --QELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAE-- 144
++LQ ++ +NK L +++ + L Q LS +E Q +E AE
Sbjct: 1880 KYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPK-LLSNMEAQHNDLEFKLAGAERE 1938
Query: 145 -----------------VLRTMELAAQSMKKAYQDMDIDKVDELMTDI------------ 175
+ + + + +KK Y +K+ + D+
Sbjct: 1939 KQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLM 1998
Query: 176 --------TEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKE 227
++QE+ I + I++ E+ EL E QEE Q L + +K+
Sbjct: 1999 REFNTQLAQKEQELEMTIKETINK---------AQEVEAELLESHQEETNQLLKKIAEKD 2049
Query: 228 EE 229
++
Sbjct: 2050 DD 2051
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 43.5 bits (101), Expect = 2e-04
Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 19/212 (8%)
Query: 56 KEKGPTPEEAIQKLKETEKILIKK--QEFLEQKIQQELQTAKKYGTKNKRAALQALRRKK 113
+EKG EE +Q ++ + +LI K QE L +K ++EL TA K K + ++ +
Sbjct: 723 REKGALIEELLQAKQDLQDLLIAKEEQEDLLRKREREL-TALKGALKEEVSS-----HDQ 776
Query: 114 RFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMT 173
++ Q D L L RE++E AT N EVL + ++ +A +M + + E
Sbjct: 777 EMDKLKEQYDAELQAL---RESVEEATKNVEVLASRSNTSE-QDQAGTEMRVKLLQEENE 832
Query: 174 DITEQQEVAQQISDAISRPMG--FGDDVDEDELLEELE-ELEQEELAQELLNVGDKEEEP 230
+ + E ++ + R + GD+ E L++ E E+ Q E E L KEE+
Sbjct: 833 KLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLE---EALVHARKEEKE 889
Query: 231 SVKLPSVPSTHLPAGPAPKVDEDEEALKQLAE 262
+V L A + + + KQL+E
Sbjct: 890 AVSARRALENELEAAQG-NLSQTTQEQKQLSE 920
Score = 36.6 bits (83), Expect = 0.023
Identities = 39/171 (22%), Positives = 81/171 (47%), Gaps = 27/171 (15%)
Query: 56 KEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRF 115
KEK +Q+ + + + +K K+Q E++ ++ +RA +AL +++
Sbjct: 979 KEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLL 1038
Query: 116 EQQLAQTDGTLSTLEFQREAIENATTN-AEVLRTMELAAQSMKKAYQDMDIDKVDELMTD 174
EQ TL LE++ EA + + + +++ ME DKV +L +
Sbjct: 1039 EQ-------TLKDLEYELEAKSHLKDDRSRLVKQME---------------DKVSQLEME 1076
Query: 175 ITEQQEVAQQISDAISRPMGFGDDVDEDELLEE---LEELEQEELAQELLN 222
+ E++ + +S+ ISR + + +ELL+E ++LE ++++ E N
Sbjct: 1077 LEEERNNSDLLSERISRSREQMEQL-RNELLQERAARQDLECDKISLERQN 1126
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/164 (25%), Positives = 82/164 (50%), Gaps = 23/164 (14%)
Query: 68 KLKETEKILIKKQEFLE--QKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGT 125
KLKE EK I+ ++ E K+Q++ ++ + ++ A +AL K+R+ +++A T
Sbjct: 110 KLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADT--- 166
Query: 126 LSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDI-TEQQEVAQQ 184
+AIE AT + E+ E A+S+++ + + ++VDEL TD+ + E+ ++
Sbjct: 167 -------ADAIEMATLDKEM---AEERAESLQQEVEALK-ERVDELTTDLEILKAEIEEK 215
Query: 185 ISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEE 228
SD G +L E+ L+ + L+ +K+E
Sbjct: 216 GSD------GAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQE 253
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/164 (25%), Positives = 82/164 (50%), Gaps = 23/164 (14%)
Query: 68 KLKETEKILIKKQEFLE--QKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGT 125
KLKE EK I+ ++ E K+Q++ ++ + ++ A +AL K+R+ +++A T
Sbjct: 224 KLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADT--- 280
Query: 126 LSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDI-TEQQEVAQQ 184
+AIE AT + E+ E A+S+++ + + ++VDEL TD+ + E+ ++
Sbjct: 281 -------ADAIEMATLDKEM---AEERAESLQQEVEALK-ERVDELTTDLEILKAEIEEK 329
Query: 185 ISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEE 228
SD G +L E+ L+ + L+ +K+E
Sbjct: 330 GSD------GAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQE 367
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/164 (25%), Positives = 82/164 (50%), Gaps = 23/164 (14%)
Query: 68 KLKETEKILIKKQEFLE--QKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGT 125
KLKE EK I+ ++ E K+Q++ ++ + ++ A +AL K+R+ +++A T
Sbjct: 110 KLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADT--- 166
Query: 126 LSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDI-TEQQEVAQQ 184
+AIE AT + E+ E A+S+++ + + ++VDEL TD+ + E+ ++
Sbjct: 167 -------ADAIEMATLDKEM---AEERAESLQQEVEALK-ERVDELTTDLEILKAEIEEK 215
Query: 185 ISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEE 228
SD G +L E+ L+ + L+ +K+E
Sbjct: 216 GSD------GAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQE 253
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 40.8 bits (94), Expect = 0.001
Identities = 42/164 (25%), Positives = 82/164 (50%), Gaps = 23/164 (14%)
Query: 68 KLKETEKILIKKQEFLE--QKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGT 125
KLKE EK I+ ++ E K+Q++ ++ + ++ A +AL K+R+ +++A T
Sbjct: 244 KLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADT--- 300
Query: 126 LSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDI-TEQQEVAQQ 184
+AIE AT + E+ E A+S+++ + + ++VDEL TD+ + E+ ++
Sbjct: 301 -------ADAIEMATLDKEM---AEERAESLQQEVEALK-ERVDELTTDLEILKAEIEEK 349
Query: 185 ISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEE 228
SD G +L E+ L+ + L+ +K+E
Sbjct: 350 GSD------GAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQE 387
>gi|40254866 chromatin modifying protein 2B [Homo sapiens]
Length = 213
Score = 40.8 bits (94), Expect = 0.001
Identities = 44/207 (21%), Positives = 86/207 (41%), Gaps = 7/207 (3%)
Query: 55 KKEKGPTPEEAIQKLKETEKILIKKQEFLE-QKIQQELQTAKKYGTKNKRAALQALRRKK 113
KK +E ++L+ T++ +I+ + LE Q+ Q EL+ K NK A ++
Sbjct: 7 KKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLV 66
Query: 114 RFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMT 173
+Q +T S + + + ++ M A++M+ + MD K + M
Sbjct: 67 HLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQ 126
Query: 174 DITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEPSVK 233
+ ++ + + I+ + DD+ + + EE Q+ + Q L +G + K
Sbjct: 127 NFQKENMKMEMTEEMINDTL---DDIFDG---SDDEEESQDIVNQVLDEIGIEISGKMAK 180
Query: 234 LPSVPSTHLPAGPAPKVDEDEEALKQL 260
PS + A + DEE +QL
Sbjct: 181 APSAARSLPSASTSKATISDEEIERQL 207
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 40.8 bits (94), Expect = 0.001
Identities = 53/207 (25%), Positives = 88/207 (42%), Gaps = 33/207 (15%)
Query: 53 KGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQ------KIQQELQTAKKYGTK------ 100
K K++ EE +++LK+ E+ K Q+ LE+ +++QE + A+ K
Sbjct: 335 KEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQ 394
Query: 101 ----NKRAALQALRRKKRFEQQL----AQTDGTLSTLEFQR-----EAIENATTNAEVLR 147
K A LQA R +K+ ++QL A+ +S LE R EA+E V
Sbjct: 395 EAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQE 454
Query: 148 TMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEE 207
+E +K A M V E + ++Q+ + A R D E+E E
Sbjct: 455 DLEKTRAELKTA---MSTPHVAEPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTE 511
Query: 208 LEELEQ-----EELAQELLNVGDKEEE 229
E+ E+ + L EL N D+ ++
Sbjct: 512 AEKNERVQKHLKALTSELANARDESKK 538
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 40.4 bits (93), Expect = 0.002
Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 32/231 (13%)
Query: 45 SGLGRLFGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRA 104
S L R + + E ++A+Q L + + K QE EQ+ Q +++ + + +
Sbjct: 515 SSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEED 574
Query: 105 ALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTM--------ELAAQSM 156
+ A RR +E +L ++ L+ EF+R+A E ++L+ E A
Sbjct: 575 LVSARRRSDLYESELRES--RLAAEEFKRKATE---CQHKLLKAKDQGKPEVGEYAKLEK 629
Query: 157 KKAYQDMDI----DKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELE 212
A Q + I +K+++ + TE E+ Q I A ++ ELE+L+
Sbjct: 630 INAEQQLKIQELQEKLEKAVKASTEATELLQNIRQA------------KERAERELEKLQ 677
Query: 213 QEELAQELLN---VGDKEEEPSVKLPSVPSTHLPAGPAPKVDEDEEALKQL 260
E + E + V +E E + V + HL K EE +K L
Sbjct: 678 NREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVL 728
>gi|13540600 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform B [Homo sapiens]
Length = 345
Score = 40.4 bits (93), Expect = 0.002
Identities = 48/207 (23%), Positives = 88/207 (42%), Gaps = 26/207 (12%)
Query: 63 EEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQT 122
+EA +L E ++ + + LE ++ Q Q + N+R + K++ E Q AQ+
Sbjct: 31 QEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQS 90
Query: 123 DGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVA 182
+S LE ++ + + + + +++A D++ K I ++
Sbjct: 91 YKQVSVLE------DDLSQTRAIKEQLHKYVRELEQANDDLERAK----RATIVSLEDFE 140
Query: 183 QQISDAISRPMGFGDDVDEDE-LLEELEELEQE--ELAQELLNVGDKEEEPSVKLPSVP- 238
Q+++ AI R ++DE E LL ++ L+ E +L QEL ++E PS P
Sbjct: 141 QRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPT 200
Query: 239 ------------STHLPAGPAPKVDED 253
S LPA P K E+
Sbjct: 201 LDCEKMDSAVQASLSLPATPVGKGTEN 227
>gi|71284108 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform A [Homo sapiens]
Length = 328
Score = 40.4 bits (93), Expect = 0.002
Identities = 48/207 (23%), Positives = 88/207 (42%), Gaps = 26/207 (12%)
Query: 63 EEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQT 122
+EA +L E ++ + + LE ++ Q Q + N+R + K++ E Q AQ+
Sbjct: 31 QEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQS 90
Query: 123 DGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVA 182
+S LE ++ + + + + +++A D++ K I ++
Sbjct: 91 YKQVSVLE------DDLSQTRAIKEQLHKYVRELEQANDDLERAK----RATIVSLEDFE 140
Query: 183 QQISDAISRPMGFGDDVDEDE-LLEELEELEQE--ELAQELLNVGDKEEEPSVKLPSVP- 238
Q+++ AI R ++DE E LL ++ L+ E +L QEL ++E PS P
Sbjct: 141 QRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPT 200
Query: 239 ------------STHLPAGPAPKVDED 253
S LPA P K E+
Sbjct: 201 LDCEKMDSAVQASLSLPATPVGKGTEN 227
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 40.0 bits (92), Expect = 0.002
Identities = 43/164 (26%), Positives = 77/164 (46%), Gaps = 18/164 (10%)
Query: 63 EEAIQKLK-ETEKILIKKQEFLEQKIQQELQTAKKYGTK----NKRAALQALRRKKRFEQ 117
E +Q LK + E+ L + E E+K +Q + +Y T+ K+ AL A +KK
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKK---- 1621
Query: 118 QLAQTDGTLSTLEFQRE-AIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDIT 176
+G L LE Q + AI+ + LR ++ + ++ +D + DE+
Sbjct: 1622 ----LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR-DEIFATAK 1676
Query: 177 EQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQEL 220
E ++ A+ + + M +D+ E + +LE+EELA+EL
Sbjct: 1677 ENEKKAKSLEADL---MQLQEDLAAAERARKQADLEKEELAEEL 1717
Score = 34.7 bits (78), Expect = 0.088
Identities = 37/179 (20%), Positives = 81/179 (45%), Gaps = 11/179 (6%)
Query: 55 KKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKR 114
++E+ E+ +QK KE ++ + + LEQK +L K + +A + +
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQK-HSQLTEEKNLLQEQLQAETELYAEAEE 908
Query: 115 FEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTD 174
+LA L + + E A E R +L A+ K A Q +D++ ++L +
Sbjct: 909 MRVRLAAKKQELEEILHEME----ARLEEEEDRGQQLQAERKKMAQQMLDLE--EQLEEE 962
Query: 175 ITEQQEVAQQISDAISRPMGFGDDV----DEDELLEELEELEQEELAQELLNVGDKEEE 229
+Q++ + A ++ D++ D++ L + +L +E ++ N+ ++EE+
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021
Score = 33.5 bits (75), Expect = 0.20
Identities = 35/146 (23%), Positives = 69/146 (47%), Gaps = 15/146 (10%)
Query: 88 QQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLR 147
++E+Q + K K +A K EQ+ +Q + L+ Q +A AE +R
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 148 TMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEE 207
+ LAA+ Q+++ + + E+ + E+++ QQ+ A + M ++L+
Sbjct: 911 -VRLAAKK-----QELE-EILHEMEARLEEEEDRGQQLQ-AERKKMA-------QQMLDL 955
Query: 208 LEELEQEELAQELLNVGDKEEEPSVK 233
E+LE+EE A++ L + E +K
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIK 981
Score = 30.8 bits (68), Expect = 1.3
Identities = 45/213 (21%), Positives = 84/213 (39%), Gaps = 39/213 (18%)
Query: 76 LIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRK-------KRFEQQLAQTDGTLST 128
L KKQ +Q + +E + KY + RA +A ++ + E+ L + T
Sbjct: 1446 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1505
Query: 129 LEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDA 188
+ + +E+ ++ + + + K+A + +++E+ T + E ++ Q DA
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE----TQMEEMKTQLEELEDELQATEDA 1561
Query: 189 --------------ISRPMGFGDDVDED-------ELLEELEELEQEELAQELLNVGDKE 227
R + D+ +E+ +L E ELE E + L K+
Sbjct: 1562 KLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKK 1621
Query: 228 EEPSVKLPSVPSTHLPAGPAPKVDEDEEALKQL 260
E +K L A A + EEA+KQL
Sbjct: 1622 LEGDLK-----DLELQADSA--IKGREEAIKQL 1647
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 40.0 bits (92), Expect = 0.002
Identities = 43/164 (26%), Positives = 77/164 (46%), Gaps = 18/164 (10%)
Query: 63 EEAIQKLK-ETEKILIKKQEFLEQKIQQELQTAKKYGTK----NKRAALQALRRKKRFEQ 117
E +Q LK + E+ L + E E+K +Q + +Y T+ K+ AL A +KK
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKK---- 1628
Query: 118 QLAQTDGTLSTLEFQRE-AIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDIT 176
+G L LE Q + AI+ + LR ++ + ++ +D + DE+
Sbjct: 1629 ----LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR-DEIFATAK 1683
Query: 177 EQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQEL 220
E ++ A+ + + M +D+ E + +LE+EELA+EL
Sbjct: 1684 ENEKKAKSLEADL---MQLQEDLAAAERARKQADLEKEELAEEL 1724
Score = 34.7 bits (78), Expect = 0.088
Identities = 37/179 (20%), Positives = 81/179 (45%), Gaps = 11/179 (6%)
Query: 55 KKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKR 114
++E+ E+ +QK KE ++ + + LEQK +L K + +A + +
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQK-HSQLTEEKNLLQEQLQAETELYAEAEE 915
Query: 115 FEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTD 174
+LA L + + E A E R +L A+ K A Q +D++ ++L +
Sbjct: 916 MRVRLAAKKQELEEILHEME----ARLEEEEDRGQQLQAERKKMAQQMLDLE--EQLEEE 969
Query: 175 ITEQQEVAQQISDAISRPMGFGDDV----DEDELLEELEELEQEELAQELLNVGDKEEE 229
+Q++ + A ++ D++ D++ L + +L +E ++ N+ ++EE+
Sbjct: 970 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1028
Score = 33.5 bits (75), Expect = 0.20
Identities = 35/146 (23%), Positives = 69/146 (47%), Gaps = 15/146 (10%)
Query: 88 QQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLR 147
++E+Q + K K +A K EQ+ +Q + L+ Q +A AE +R
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 148 TMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEE 207
+ LAA+ Q+++ + + E+ + E+++ QQ+ A + M ++L+
Sbjct: 918 -VRLAAKK-----QELE-EILHEMEARLEEEEDRGQQLQ-AERKKMA-------QQMLDL 962
Query: 208 LEELEQEELAQELLNVGDKEEEPSVK 233
E+LE+EE A++ L + E +K
Sbjct: 963 EEQLEEEEAARQKLQLEKVTAEAKIK 988
Score = 30.8 bits (68), Expect = 1.3
Identities = 45/213 (21%), Positives = 84/213 (39%), Gaps = 39/213 (18%)
Query: 76 LIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRK-------KRFEQQLAQTDGTLST 128
L KKQ +Q + +E + KY + RA +A ++ + E+ L + T
Sbjct: 1453 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1512
Query: 129 LEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDA 188
+ + +E+ ++ + + + K+A + +++E+ T + E ++ Q DA
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE----TQMEEMKTQLEELEDELQATEDA 1568
Query: 189 --------------ISRPMGFGDDVDED-------ELLEELEELEQEELAQELLNVGDKE 227
R + D+ +E+ +L E ELE E + L K+
Sbjct: 1569 KLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKK 1628
Query: 228 EEPSVKLPSVPSTHLPAGPAPKVDEDEEALKQL 260
E +K L A A + EEA+KQL
Sbjct: 1629 LEGDLK-----DLELQADSA--IKGREEAIKQL 1654
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 40.0 bits (92), Expect = 0.002
Identities = 43/164 (26%), Positives = 77/164 (46%), Gaps = 18/164 (10%)
Query: 63 EEAIQKLK-ETEKILIKKQEFLEQKIQQELQTAKKYGTK----NKRAALQALRRKKRFEQ 117
E +Q LK + E+ L + E E+K +Q + +Y T+ K+ AL A +KK
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKK---- 1628
Query: 118 QLAQTDGTLSTLEFQRE-AIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDIT 176
+G L LE Q + AI+ + LR ++ + ++ +D + DE+
Sbjct: 1629 ----LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR-DEIFATAK 1683
Query: 177 EQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQEL 220
E ++ A+ + + M +D+ E + +LE+EELA+EL
Sbjct: 1684 ENEKKAKSLEADL---MQLQEDLAAAERARKQADLEKEELAEEL 1724
Score = 34.7 bits (78), Expect = 0.088
Identities = 37/179 (20%), Positives = 81/179 (45%), Gaps = 11/179 (6%)
Query: 55 KKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKR 114
++E+ E+ +QK KE ++ + + LEQK +L K + +A + +
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQK-HSQLTEEKNLLQEQLQAETELYAEAEE 915
Query: 115 FEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTD 174
+LA L + + E A E R +L A+ K A Q +D++ ++L +
Sbjct: 916 MRVRLAAKKQELEEILHEME----ARLEEEEDRGQQLQAERKKMAQQMLDLE--EQLEEE 969
Query: 175 ITEQQEVAQQISDAISRPMGFGDDV----DEDELLEELEELEQEELAQELLNVGDKEEE 229
+Q++ + A ++ D++ D++ L + +L +E ++ N+ ++EE+
Sbjct: 970 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1028
Score = 33.5 bits (75), Expect = 0.20
Identities = 35/146 (23%), Positives = 69/146 (47%), Gaps = 15/146 (10%)
Query: 88 QQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLR 147
++E+Q + K K +A K EQ+ +Q + L+ Q +A AE +R
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 148 TMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEE 207
+ LAA+ Q+++ + + E+ + E+++ QQ+ A + M ++L+
Sbjct: 918 -VRLAAKK-----QELE-EILHEMEARLEEEEDRGQQLQ-AERKKMA-------QQMLDL 962
Query: 208 LEELEQEELAQELLNVGDKEEEPSVK 233
E+LE+EE A++ L + E +K
Sbjct: 963 EEQLEEEEAARQKLQLEKVTAEAKIK 988
Score = 30.8 bits (68), Expect = 1.3
Identities = 45/213 (21%), Positives = 84/213 (39%), Gaps = 39/213 (18%)
Query: 76 LIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRK-------KRFEQQLAQTDGTLST 128
L KKQ +Q + +E + KY + RA +A ++ + E+ L + T
Sbjct: 1453 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1512
Query: 129 LEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDA 188
+ + +E+ ++ + + + K+A + +++E+ T + E ++ Q DA
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE----TQMEEMKTQLEELEDELQATEDA 1568
Query: 189 --------------ISRPMGFGDDVDED-------ELLEELEELEQEELAQELLNVGDKE 227
R + D+ +E+ +L E ELE E + L K+
Sbjct: 1569 KLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKK 1628
Query: 228 EEPSVKLPSVPSTHLPAGPAPKVDEDEEALKQL 260
E +K L A A + EEA+KQL
Sbjct: 1629 LEGDLK-----DLELQADSA--IKGREEAIKQL 1654
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 40.0 bits (92), Expect = 0.002
Identities = 43/164 (26%), Positives = 77/164 (46%), Gaps = 18/164 (10%)
Query: 63 EEAIQKLK-ETEKILIKKQEFLEQKIQQELQTAKKYGTK----NKRAALQALRRKKRFEQ 117
E +Q LK + E+ L + E E+K +Q + +Y T+ K+ AL A +KK
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKK---- 1621
Query: 118 QLAQTDGTLSTLEFQRE-AIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDIT 176
+G L LE Q + AI+ + LR ++ + ++ +D + DE+
Sbjct: 1622 ----LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR-DEIFATAK 1676
Query: 177 EQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQEL 220
E ++ A+ + + M +D+ E + +LE+EELA+EL
Sbjct: 1677 ENEKKAKSLEADL---MQLQEDLAAAERARKQADLEKEELAEEL 1717
Score = 34.7 bits (78), Expect = 0.088
Identities = 37/179 (20%), Positives = 81/179 (45%), Gaps = 11/179 (6%)
Query: 55 KKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKR 114
++E+ E+ +QK KE ++ + + LEQK +L K + +A + +
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQK-HSQLTEEKNLLQEQLQAETELYAEAEE 908
Query: 115 FEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTD 174
+LA L + + E A E R +L A+ K A Q +D++ ++L +
Sbjct: 909 MRVRLAAKKQELEEILHEME----ARLEEEEDRGQQLQAERKKMAQQMLDLE--EQLEEE 962
Query: 175 ITEQQEVAQQISDAISRPMGFGDDV----DEDELLEELEELEQEELAQELLNVGDKEEE 229
+Q++ + A ++ D++ D++ L + +L +E ++ N+ ++EE+
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021
Score = 33.5 bits (75), Expect = 0.20
Identities = 35/146 (23%), Positives = 69/146 (47%), Gaps = 15/146 (10%)
Query: 88 QQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLR 147
++E+Q + K K +A K EQ+ +Q + L+ Q +A AE +R
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 148 TMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEE 207
+ LAA+ Q+++ + + E+ + E+++ QQ+ A + M ++L+
Sbjct: 911 -VRLAAKK-----QELE-EILHEMEARLEEEEDRGQQLQ-AERKKMA-------QQMLDL 955
Query: 208 LEELEQEELAQELLNVGDKEEEPSVK 233
E+LE+EE A++ L + E +K
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIK 981
Score = 30.8 bits (68), Expect = 1.3
Identities = 45/213 (21%), Positives = 84/213 (39%), Gaps = 39/213 (18%)
Query: 76 LIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRK-------KRFEQQLAQTDGTLST 128
L KKQ +Q + +E + KY + RA +A ++ + E+ L + T
Sbjct: 1446 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1505
Query: 129 LEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDA 188
+ + +E+ ++ + + + K+A + +++E+ T + E ++ Q DA
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE----TQMEEMKTQLEELEDELQATEDA 1561
Query: 189 --------------ISRPMGFGDDVDED-------ELLEELEELEQEELAQELLNVGDKE 227
R + D+ +E+ +L E ELE E + L K+
Sbjct: 1562 KLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKK 1621
Query: 228 EEPSVKLPSVPSTHLPAGPAPKVDEDEEALKQL 260
E +K L A A + EEA+KQL
Sbjct: 1622 LEGDLK-----DLELQADSA--IKGREEAIKQL 1647
>gi|50980301 myosin phosphatase-Rho interacting protein isoform 2
[Homo sapiens]
Length = 1025
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/147 (21%), Positives = 75/147 (51%), Gaps = 6/147 (4%)
Query: 85 QKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAE 144
+++++EL+ +++ + + ++ALRR+ E Q Q + + + ++ ++ +ENA A+
Sbjct: 781 EEMERELEKSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHL-AQ 839
Query: 145 VLRTMELAAQSMKKAYQDMDIDKVD---ELMTDITEQQEV--AQQISDAISRPMGFGDDV 199
L A + ++ Q+++ + L +IT + + +A P+ G D
Sbjct: 840 ALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDA 899
Query: 200 DEDELLEELEELEQEELAQELLNVGDK 226
E E+L ++E E + L QE+ ++ D+
Sbjct: 900 YELEVLLRVKESEIQYLKQEISSLKDE 926
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,813,247
Number of Sequences: 37866
Number of extensions: 540427
Number of successful extensions: 4731
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 416
Number of HSP's that attempted gapping in prelim test: 3911
Number of HSP's gapped (non-prelim): 1131
length of query: 265
length of database: 18,247,518
effective HSP length: 100
effective length of query: 165
effective length of database: 14,460,918
effective search space: 2386051470
effective search space used: 2386051470
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.