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Search of human proteins with 40538880
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40538880 aquaporin 12A [Homo sapiens]
(295 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40538880 aquaporin 12A [Homo sapiens] 593 e-170
gi|156447037 aquaporin 12B [Homo sapiens] 579 e-166
gi|27370565 aquaporin 11 [Homo sapiens] 103 2e-22
gi|86792455 aquaporin 6 [Homo sapiens] 40 0.003
gi|4502183 aquaporin 5 [Homo sapiens] 38 0.012
gi|45446752 aquaporin 8 [Homo sapiens] 37 0.027
gi|37694062 aquaporin 1 [Homo sapiens] 35 0.079
gi|4502179 aquaporin 2 [Homo sapiens] 34 0.13
gi|4755125 aquaporin 4 isoform b [Homo sapiens] 33 0.39
gi|4502181 aquaporin 4 isoform a [Homo sapiens] 33 0.39
gi|8923887 zinc finger protein 395 [Homo sapiens] 33 0.39
gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Hom... 32 0.67
gi|6912506 major intrinsic protein of lens fiber [Homo sapiens] 30 3.3
gi|46255035 formiminotransferase cyclodeaminase [Homo sapiens] 30 3.3
gi|11140815 formiminotransferase cyclodeaminase [Homo sapiens] 30 3.3
gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),... 30 3.3
gi|194239674 crystallin, zeta isoform a [Homo sapiens] 30 3.3
gi|13236495 crystallin, zeta isoform a [Homo sapiens] 30 3.3
gi|197927207 crystallin, zeta isoform c [Homo sapiens] 30 3.3
gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger)... 29 4.3
gi|124107604 killer cell immunoglobulin-like receptor, two domai... 28 7.4
gi|124107606 killer cell immunoglobulin-like receptor, two domai... 28 7.4
gi|124107610 killer cell immunoglobulin-like receptor, two domai... 28 7.4
gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Hom... 28 7.4
gi|6912474 killer cell immunoglobulin-like receptor, two domains... 28 9.6
gi|169171432 PREDICTED: similar to hCG2014367 [Homo sapiens] 28 9.6
gi|169171899 PREDICTED: similar to hCG2014367 [Homo sapiens] 28 9.6
gi|169171130 PREDICTED: hypothetical protein LOC100130600 [Homo ... 28 9.6
gi|239509024 PREDICTED: similar to hCG2014367 [Homo sapiens] 28 9.6
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 28 9.6
>gi|40538880 aquaporin 12A [Homo sapiens]
Length = 295
Score = 593 bits (1529), Expect = e-170
Identities = 295/295 (100%), Positives = 295/295 (100%)
Query: 1 MAGLNVSLSFFFATFALCEAARRASKALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLL 60
MAGLNVSLSFFFATFALCEAARRASKALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLL
Sbjct: 1 MAGLNVSLSFFFATFALCEAARRASKALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLL 60
Query: 61 LTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLC 120
LTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLC
Sbjct: 61 LTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLC 120
Query: 121 WAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAV 180
WAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAV
Sbjct: 121 WAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAV 180
Query: 181 ALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLHQG 240
ALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLHQG
Sbjct: 181 ALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLHQG 240
Query: 241 RLPHLFQRNLFYGQKNKYRAPRGKPAPASGDTQTPAKGSSVREPGRSGVEGPHSS 295
RLPHLFQRNLFYGQKNKYRAPRGKPAPASGDTQTPAKGSSVREPGRSGVEGPHSS
Sbjct: 241 RLPHLFQRNLFYGQKNKYRAPRGKPAPASGDTQTPAKGSSVREPGRSGVEGPHSS 295
>gi|156447037 aquaporin 12B [Homo sapiens]
Length = 307
Score = 579 bits (1493), Expect = e-166
Identities = 292/307 (95%), Positives = 293/307 (95%), Gaps = 12/307 (3%)
Query: 1 MAGLNVSLSFFFATFALCEAARRASKALLPVGAYEVFAREA------------MRTLVEL 48
MAGLNVSLSFFFATF LCEAARRASKALLPVGAYEVFAREA MRTLVEL
Sbjct: 1 MAGLNVSLSFFFATFTLCEAARRASKALLPVGAYEVFAREAVGAVQLGACFLEMRTLVEL 60
Query: 49 GPWAGDFGPDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGL 108
GPWAGDFGPDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAE+SLPGTLLKLAAQGL
Sbjct: 61 GPWAGDFGPDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEESLPGTLLKLAAQGL 120
Query: 109 GMQAACTLMRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHL 168
GMQAACTL RLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHL
Sbjct: 121 GMQAACTLTRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHL 180
Query: 169 RHSPPAYSGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPL 228
RHSPPAYSGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPL
Sbjct: 181 RHSPPAYSGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPL 240
Query: 229 TGMVLAVLLHQGRLPHLFQRNLFYGQKNKYRAPRGKPAPASGDTQTPAKGSSVREPGRSG 288
TGMVLAVLLHQGRLPHLFQRNLFYGQKNKYRAPRGKPAPASGDTQTPAKGSSVREPGRSG
Sbjct: 241 TGMVLAVLLHQGRLPHLFQRNLFYGQKNKYRAPRGKPAPASGDTQTPAKGSSVREPGRSG 300
Query: 289 VEGPHSS 295
VEGPHSS
Sbjct: 301 VEGPHSS 307
>gi|27370565 aquaporin 11 [Homo sapiens]
Length = 271
Score = 103 bits (256), Expect = 2e-22
Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 2/189 (1%)
Query: 57 PDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTL 116
P LTL++ L HG+TL G S+NP + + ++ S ++L AQ + +
Sbjct: 75 PTWTLTLVYFFSLVHGLTLVGTSSNPCGVMMQMMLGGMSPETGAVRLLAQLVSALCSRYC 134
Query: 117 MRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYS 176
W+ L+ H+ + A C + +R + + EA C+F FH LLH +
Sbjct: 135 TSALWSLGLTQYHVSERSFA--CKNPIRVDLLKAVITEAVCSFLFHSALLHFQEVRTKLR 192
Query: 177 GPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVL 236
+A L+T Y G T A FNPALA S+ F C ++ VYWL P G++L +L
Sbjct: 193 IHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYWLAPSLGILLMIL 252
Query: 237 LHQGRLPHL 245
+ LP L
Sbjct: 253 MFSFFLPWL 261
>gi|86792455 aquaporin 6 [Homo sapiens]
Length = 282
Score = 39.7 bits (91), Expect = 0.003
Identities = 58/243 (23%), Positives = 90/243 (37%), Gaps = 38/243 (15%)
Query: 12 FATFALCEAARRASKAL----LPVGAYEVFAREAMRTLVELGPWAGDFGPDLLLTLLFLL 67
+A+ C + S+AL L G Y F ++ W L + + F L
Sbjct: 11 WASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMR------WPTALPSVLQIAITFNL 64
Query: 68 FLAHGVTL----DGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCWAW 123
A V + GA ANP V+L + + SLP + +AAQ +G L+
Sbjct: 65 VTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPG 124
Query: 124 ELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLL--------HLRHSPPAY 175
++ + + + +R SV G V L L SP
Sbjct: 125 DIRETLGI---------NVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATM 175
Query: 176 SGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAV 235
G +VAL + + FT NPA + T+ V+W+GPL G +LA
Sbjct: 176 IGISVALGHLIGIH----FTGCSMNPARSFGPAIIIGKFTV---HWVFWVGPLMGALLAS 228
Query: 236 LLH 238
L++
Sbjct: 229 LIY 231
>gi|4502183 aquaporin 5 [Homo sapiens]
Length = 265
Score = 37.7 bits (86), Expect = 0.012
Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 13/168 (7%)
Query: 75 LDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCWAWELSDLHLLQSL 134
+ G NP ++L + + SL +AAQ +G A ++ + ++ L+ +L
Sbjct: 63 VSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGIL-----YGVAPLNARGNL 117
Query: 135 MAQSCSSALRTSVPHGALVEAACAF----CFHLTLLHLRHSPPAYSGPAVALLVTVTAYT 190
+ ++ T+ +VE F C + R SP ++ L VT+
Sbjct: 118 AVNALNN--NTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLV 175
Query: 191 AGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLH 238
FT NPA + + + +V +W+GP+ G VLA +L+
Sbjct: 176 GIYFTGCSMNPARSFGPAVVMNRFSPAHWV--FWVGPIVGAVLAAILY 221
>gi|45446752 aquaporin 8 [Homo sapiens]
Length = 261
Score = 36.6 bits (83), Expect = 0.027
Identities = 51/202 (25%), Positives = 72/202 (35%), Gaps = 20/202 (9%)
Query: 44 TLVELGPWAGDFGPDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEQSLPGTLLKL 103
+++E G G P L L L +A + G NP VSL L+ +L L
Sbjct: 55 SVIENGTDTGLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYW 114
Query: 104 AAQGLGMQAACTLMRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHL 163
+Q LG L + + + +A T G + A A
Sbjct: 115 VSQLLGGMLGAALAKAVSP---------EERFWNASGAAFVTVQEQGQVAGALVAEIILT 165
Query: 164 TLLHLRHSPPAYS----GP----AVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHT 215
TLL L A + GP ++ VTV GP + NPA A +
Sbjct: 166 TLLALAVCMGAINEKTKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANH-- 223
Query: 216 LLEYVQVYWLGPLTGMVLAVLL 237
+ +YWLGPL +L LL
Sbjct: 224 -WNFHWIYWLGPLLAGLLVGLL 244
>gi|37694062 aquaporin 1 [Homo sapiens]
Length = 269
Score = 35.0 bits (79), Expect = 0.079
Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 16/169 (9%)
Query: 75 LDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCWAWELSDLHLLQSL 134
+ GA NP V+L L + S+ L+ + AQ +G A ++ + L+ L ++
Sbjct: 70 ISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITS-SLTGNSLGRND 128
Query: 135 MAQSCSSALRTSVPH-GALVEAACAFCFHLTLLHLRHSPPAYSGP-AVALLVTVTAYTAG 192
+A +S + G L C L R S P A+ L V + A
Sbjct: 129 LADGVNSGQGLGIEIIGTLQLVLCV----LATTDRRRRDLGGSAPLAIGLSVALGHLLAI 184
Query: 193 PFTSAFFNPALA---ASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLH 238
+T NPA + A +T S H ++W+GP G LAVL++
Sbjct: 185 DYTGCGINPARSFGSAVITHNFSNHW------IFWVGPFIGGALAVLIY 227
>gi|4502179 aquaporin 2 [Homo sapiens]
Length = 271
Score = 34.3 bits (77), Expect = 0.13
Identities = 39/167 (23%), Positives = 63/167 (37%), Gaps = 12/167 (7%)
Query: 75 LDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCWAWELSDLHLLQSL 134
+ GA NP V++ + S+ +AAQ LG A L+ +D+ ++
Sbjct: 62 ISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITP---ADIRGDLAV 118
Query: 135 MAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAVALLVTVTAYTAGPF 194
A S S+ +V + C + R P ++ V + +
Sbjct: 119 NALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHY 178
Query: 195 TSAFFNPALA---ASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLH 238
T NPA + A VT H V+W+GPL G +L LL+
Sbjct: 179 TGCSMNPARSLAPAVVTGKFDDHW------VFWIGPLVGAILGSLLY 219
>gi|4755125 aquaporin 4 isoform b [Homo sapiens]
Length = 301
Score = 32.7 bits (73), Expect = 0.39
Identities = 46/189 (24%), Positives = 75/189 (39%), Gaps = 18/189 (9%)
Query: 59 LLLTLLFLLFLAHGVT----LDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAAC 114
+L++L F L +A V + G NP V++ + S+ ++ +AAQ LG
Sbjct: 49 VLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGA 108
Query: 115 TLMRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPA 174
++ L ++ ++ L L HG LVE F T+ S
Sbjct: 109 GILYL-----VTPPSVVGGLGVTMVHGNLTAG--HGLLVELIITFQLVFTIFASCDSKRT 161
Query: 175 YSGPAVALL----VTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTG 230
++AL V + A +T A NPA + E +YW+GP+ G
Sbjct: 162 DVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNW---ENHWIYWVGPIIG 218
Query: 231 MVLAVLLHQ 239
VLA L++
Sbjct: 219 AVLAGGLYE 227
>gi|4502181 aquaporin 4 isoform a [Homo sapiens]
Length = 323
Score = 32.7 bits (73), Expect = 0.39
Identities = 46/189 (24%), Positives = 75/189 (39%), Gaps = 18/189 (9%)
Query: 59 LLLTLLFLLFLAHGVT----LDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAAC 114
+L++L F L +A V + G NP V++ + S+ ++ +AAQ LG
Sbjct: 71 VLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGA 130
Query: 115 TLMRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPA 174
++ L ++ ++ L L HG LVE F T+ S
Sbjct: 131 GILYL-----VTPPSVVGGLGVTMVHGNLTAG--HGLLVELIITFQLVFTIFASCDSKRT 183
Query: 175 YSGPAVALL----VTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTG 230
++AL V + A +T A NPA + E +YW+GP+ G
Sbjct: 184 DVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNW---ENHWIYWVGPIIG 240
Query: 231 MVLAVLLHQ 239
VLA L++
Sbjct: 241 AVLAGGLYE 249
>gi|8923887 zinc finger protein 395 [Homo sapiens]
Length = 513
Score = 32.7 bits (73), Expect = 0.39
Identities = 16/66 (24%), Positives = 34/66 (51%)
Query: 145 TSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAVALLVTVTAYTAGPFTSAFFNPALA 204
+S+P GAL ++A +H+ H + P++ P + T ++ A P + +P +
Sbjct: 386 SSLPSGALSKSAPGSFWHIQADHAYQALPSFQIPVSPHIYTSVSWAAAPSAACSLSPVRS 445
Query: 205 ASVTFA 210
S++F+
Sbjct: 446 RSLSFS 451
>gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Homo
sapiens]
Length = 1151
Score = 32.0 bits (71), Expect = 0.67
Identities = 43/168 (25%), Positives = 62/168 (36%), Gaps = 38/168 (22%)
Query: 136 AQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAVALLVTVTAYTAGPFT 195
+ S S LR +VP C + L+ SP Y V LV V T
Sbjct: 586 SSSSSDGLRDNVP-----------CLKVKNSPLKQSP-GYQTELVIQLVWVGGEPPQQIT 633
Query: 196 SAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLHQGRLPHLFQRNLFYGQK 255
S N + V C+G +++Y+Q AVLL+ G + YG
Sbjct: 634 SLAVNSSYGLVVFGNCNGIAMVDYLQ-----------KAVLLNLGTIE-------LYGSN 675
Query: 256 NKY----RAPRGKPAPASGDTQTPAKGSSVRE----PGRSGVEGPHSS 295
+ Y R+PR P+ ++G+ V E SG PH+S
Sbjct: 676 DPYRREPRSPRKSRQPSGAGLCDISEGTVVPEDRCKSPTSGSSSPHNS 723
>gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]
Length = 263
Score = 29.6 bits (65), Expect = 3.3
Identities = 39/168 (23%), Positives = 63/168 (37%), Gaps = 14/168 (8%)
Query: 75 LDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCWAWELSDLHLLQSL 134
+ GA NP V+ + ++ SL +AAQ LG A ++ + ++ + +L
Sbjct: 62 ISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVL-----YSVTPPAVRGNL 116
Query: 135 MAQSCSSALRTSVPHGALVE----AACAFCFHLTLLHLRHSPPAYSGPAVALLVTVTAYT 190
+ A+ SV VE C T R+ AV + +
Sbjct: 117 ALNTLHPAV--SVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLF 174
Query: 191 AGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLH 238
+T A NPA + + T VYW+GP+ G L LL+
Sbjct: 175 GMYYTGAGMNPARSFAPAILTGNFT---NHWVYWVGPIIGGGLGSLLY 219
>gi|46255035 formiminotransferase cyclodeaminase [Homo sapiens]
Length = 541
Score = 29.6 bits (65), Expect = 3.3
Identities = 41/168 (24%), Positives = 60/168 (35%), Gaps = 35/168 (20%)
Query: 19 EAARRASKALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLLLTLLFLLFLAHGVTLDGA 78
EAAR S+ LP A EA+ ++ WA DFGP + + G T GA
Sbjct: 128 EAARMDSRRTLP--AIRAGEYEALPKKLQQADWAPDFGPSSFVP-------SWGATATGA 178
Query: 79 SANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCW-AWELSDLHL------- 130
L ++ L L QG G L ++ W L + +L
Sbjct: 179 RKFLIAFNINLLGTKEQAHRIALNLREQGRGKDQPGRLKKVQGIGWYLDEKNLAQVSTNL 238
Query: 131 -------LQSLMAQSCSSALRTS-----------VPHGALVEAACAFC 160
L ++ ++C A S VP AL++AA +C
Sbjct: 239 LDFEVTALHTVYEETCREAQELSLPVVGSQLVGLVPLKALLDAAAFYC 286
>gi|11140815 formiminotransferase cyclodeaminase [Homo sapiens]
Length = 541
Score = 29.6 bits (65), Expect = 3.3
Identities = 41/168 (24%), Positives = 60/168 (35%), Gaps = 35/168 (20%)
Query: 19 EAARRASKALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLLLTLLFLLFLAHGVTLDGA 78
EAAR S+ LP A EA+ ++ WA DFGP + + G T GA
Sbjct: 128 EAARMDSRRTLP--AIRAGEYEALPKKLQQADWAPDFGPSSFVP-------SWGATATGA 178
Query: 79 SANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCW-AWELSDLHL------- 130
L ++ L L QG G L ++ W L + +L
Sbjct: 179 RKFLIAFNINLLGTKEQAHRIALNLREQGRGKDQPGRLKKVQGIGWYLDEKNLAQVSTNL 238
Query: 131 -------LQSLMAQSCSSALRTS-----------VPHGALVEAACAFC 160
L ++ ++C A S VP AL++AA +C
Sbjct: 239 LDFEVTALHTVYEETCREAQELSLPVVGSQLVGLVPLKALLDAAAFYC 286
>gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),
member 2 [Homo sapiens]
Length = 812
Score = 29.6 bits (65), Expect = 3.3
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 57 PDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFL--MAEQSLPGTLLKLAAQGLGMQAAC 114
P + T +F L+L + LD PT E + + ++ GTL G+ + C
Sbjct: 133 PPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVGTLWNSIGIGVSLFGIC 192
Query: 115 TLMRLCWAWELSDLHLLQSLMAQSCSSAL 143
+ A+ LSD+ LLQ+L+ S SA+
Sbjct: 193 QIE----AFGLSDITLLQNLLFGSLISAV 217
>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 29.6 bits (65), Expect = 3.3
Identities = 26/108 (24%), Positives = 50/108 (46%), Gaps = 12/108 (11%)
Query: 26 KALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLLLTLLF-------LLFLAHG--VTLD 76
K +L GA+EVF + + ++ + G+ G D+++ +L L L+HG V +
Sbjct: 187 KIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVV 246
Query: 77 GASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTL---MRLCW 121
G+ ++ ++ + E S+ G L + + Q A L M + W
Sbjct: 247 GSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW 294
>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 29.6 bits (65), Expect = 3.3
Identities = 26/108 (24%), Positives = 50/108 (46%), Gaps = 12/108 (11%)
Query: 26 KALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLLLTLLF-------LLFLAHG--VTLD 76
K +L GA+EVF + + ++ + G+ G D+++ +L L L+HG V +
Sbjct: 187 KIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVV 246
Query: 77 GASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTL---MRLCW 121
G+ ++ ++ + E S+ G L + + Q A L M + W
Sbjct: 247 GSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW 294
>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
Length = 192
Score = 29.6 bits (65), Expect = 3.3
Identities = 26/108 (24%), Positives = 50/108 (46%), Gaps = 12/108 (11%)
Query: 26 KALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLLLTLLF-------LLFLAHG--VTLD 76
K +L GA+EVF + + ++ + G+ G D+++ +L L L+HG V +
Sbjct: 50 KIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVV 109
Query: 77 GASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTL---MRLCW 121
G+ ++ ++ + E S+ G L + + Q A L M + W
Sbjct: 110 GSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW 157
>gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger),
member 4 [Homo sapiens]
Length = 798
Score = 29.3 bits (64), Expect = 4.3
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 57 PDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFL--MAEQSLPGTLLKLAAQGLGMQAAC 114
P ++ + ++ L+L + L+G PT E + + ++ G L+ GL + C
Sbjct: 122 PPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLYLIC 181
Query: 115 TLMRLCWAWELSDLHLLQSLMAQSCSSAL 143
+ A+ L D++LLQ+L+ S SA+
Sbjct: 182 QVK----AFGLGDVNLLQNLLFGSLISAV 206
>gi|124107604 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform b [Homo sapiens]
Length = 273
Score = 28.5 bits (62), Expect = 7.4
Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 170 HSPPAYSGPAVALLVTVTAYTAGPFTSAFFNPALAA--SVTFACSGHT 215
HSP +S P+ L++ VT P +A P + A +VT +CS +
Sbjct: 103 HSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGENVTLSCSSQS 150
>gi|124107606 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform a [Homo sapiens]
Length = 377
Score = 28.5 bits (62), Expect = 7.4
Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 170 HSPPAYSGPAVALLVTVTAYTAGPFTSAFFNPALAA--SVTFACSGHT 215
HSP +S P+ L++ VT P +A P + A +VT +CS +
Sbjct: 103 HSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGENVTLSCSSQS 150
>gi|124107610 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform c [Homo sapiens]
Length = 342
Score = 28.5 bits (62), Expect = 7.4
Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 170 HSPPAYSGPAVALLVTVTAYTAGPFTSAFFNPALAA--SVTFACSGHT 215
HSP +S P+ L++ VT P +A P + A +VT +CS +
Sbjct: 103 HSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGENVTLSCSSQS 150
>gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Homo
sapiens]
Length = 1115
Score = 28.5 bits (62), Expect = 7.4
Identities = 38/152 (25%), Positives = 56/152 (36%), Gaps = 34/152 (22%)
Query: 136 AQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAVALLVTVTAYTAGPFT 195
+ S S LR +VP C + L+ SP Y V LV V T
Sbjct: 586 SSSSSDGLRDNVP-----------CLKVKNSPLKQSP-GYQTELVIQLVWVGGEPPQQIT 633
Query: 196 SAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLHQGRLPHLFQRNLFYGQK 255
S N + V C+G +++Y+Q AVLL+ G + YG
Sbjct: 634 SLAVNSSYGLVVFGNCNGIAMVDYLQ-----------KAVLLNLGTIE-------LYGSN 675
Query: 256 NKY----RAPRGKPAPASGDTQTPAKGSSVRE 283
+ Y R+PR P+ ++G+ V E
Sbjct: 676 DPYRREPRSPRKSRQPSGAGLCDISEGTVVPE 707
>gi|6912474 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 3 [Homo sapiens]
Length = 304
Score = 28.1 bits (61), Expect = 9.6
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Query: 170 HSPPAYSGPAVALLVTVTAYTAGPFTSAFFNPALAA--SVTFACS 212
HSP +S P+ L + +T P SA P + A SVT +CS
Sbjct: 106 HSPYQFSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCS 150
>gi|169171432 PREDICTED: similar to hCG2014367 [Homo sapiens]
Length = 594
Score = 28.1 bits (61), Expect = 9.6
Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 174 AYSGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVL 233
+YSGP + + A P + P L++S T++ + + L + LGP G
Sbjct: 258 SYSGPKPSTQYGAPGHFAAPAFGKVYGPTLSSSYTYSDASSSTLAPTS-FLLGP--GAFN 314
Query: 234 AVLLHQG-RLPHLFQRNLFYGQKNKYRAPRGKPA---PASGDTQTP 275
A QG R L R L G + R PRG P P D TP
Sbjct: 315 AQESGQGSRAGPL--RPLPLGMGAQGRLPRGNPTDMDPTLEDPTTP 358
>gi|169171899 PREDICTED: similar to hCG2014367 [Homo sapiens]
Length = 594
Score = 28.1 bits (61), Expect = 9.6
Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 174 AYSGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVL 233
+YSGP + + A P + P L++S T++ + + L + LGP G
Sbjct: 258 SYSGPKPSTQYGAPGHFAAPAFGKVYGPTLSSSYTYSDASSSTLAPTS-FLLGP--GAFN 314
Query: 234 AVLLHQG-RLPHLFQRNLFYGQKNKYRAPRGKPA---PASGDTQTP 275
A QG R L R L G + R PRG P P D TP
Sbjct: 315 AQESGQGSRAGPL--RPLPLGMGAQGRLPRGNPTDMDPTLEDPTTP 358
>gi|169171130 PREDICTED: hypothetical protein LOC100130600 [Homo
sapiens]
Length = 594
Score = 28.1 bits (61), Expect = 9.6
Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 174 AYSGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVL 233
+YSGP + + A P + P L++S T++ + + L + LGP G
Sbjct: 258 SYSGPKPSTQYGAPGHFAAPAFGKVYGPTLSSSYTYSDASSSTLAPTS-FLLGP--GAFN 314
Query: 234 AVLLHQG-RLPHLFQRNLFYGQKNKYRAPRGKPA---PASGDTQTP 275
A QG R L R L G + R PRG P P D TP
Sbjct: 315 AQESGQGSRAGPL--RPLPLGMGAQGRLPRGNPTDMDPTLEDPTTP 358
>gi|239509024 PREDICTED: similar to hCG2014367 [Homo sapiens]
Length = 594
Score = 28.1 bits (61), Expect = 9.6
Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 174 AYSGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVL 233
+YSGP + + A P + P L++S T++ + + L + LGP G
Sbjct: 258 SYSGPKPSTQYGAPGHFAAPAFGKVYGPTLSSSYTYSDASSSTLAPTS-FLLGP--GAFN 314
Query: 234 AVLLHQG-RLPHLFQRNLFYGQKNKYRAPRGKPA---PASGDTQTP 275
A QG R L R L G + R PRG P P D TP
Sbjct: 315 AQESGQGSRAGPL--RPLPLGMGAQGRLPRGNPTDMDPTLEDPTTP 358
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
[Homo sapiens]
Length = 1650
Score = 28.1 bits (61), Expect = 9.6
Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 2/34 (5%)
Query: 261 PRGKPAPASGDTQTPAKGSS--VREPGRSGVEGP 292
P G P PA + A GS + PGR G +GP
Sbjct: 921 PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP 954
Score = 28.1 bits (61), Expect = 9.6
Identities = 13/37 (35%), Positives = 19/37 (51%), Gaps = 5/37 (13%)
Query: 261 PRGKPAP-----ASGDTQTPAKGSSVREPGRSGVEGP 292
P G+P P A+G+ P + + GR GV+GP
Sbjct: 945 PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 981
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,503,913
Number of Sequences: 37866
Number of extensions: 510528
Number of successful extensions: 2395
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2373
Number of HSP's gapped (non-prelim): 40
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.