BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|40316915 arginyl aminopeptidase [Homo sapiens] (650 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|40316915 arginyl aminopeptidase [Homo sapiens] 1344 0.0 gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Ho... 456 e-128 gi|4505029 leukotriene A4 hydrolase [Homo sapiens] 378 e-104 gi|24432058 aminopeptidase O [Homo sapiens] 100 5e-21 gi|157266300 membrane alanine aminopeptidase precursor [Homo sap... 97 5e-20 gi|94818891 type 1 tumor necrosis factor receptor shedding amino... 95 2e-19 gi|94818901 type 1 tumor necrosis factor receptor shedding amino... 95 2e-19 gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens] 92 1e-18 gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens] 92 1e-18 gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 88 3e-17 gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 88 3e-17 gi|194239713 laeverin [Homo sapiens] 82 2e-15 gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens] 82 2e-15 gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo ... 80 8e-15 gi|132814467 glutamyl aminopeptidase [Homo sapiens] 76 1e-13 gi|239754599 PREDICTED: hypothetical protein [Homo sapiens] 32 1.8 gi|42475941 zinc finger protein 261 [Homo sapiens] 32 1.8 gi|4827067 zinc finger protein 261 [Homo sapiens] 32 1.8 gi|219273466 hypothetical protein LOC29125 [Homo sapiens] 31 3.1 gi|94536786 hypothetical protein LOC79091 [Homo sapiens] 31 3.1 gi|98986321 gliomedin [Homo sapiens] 31 3.1 gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] 31 3.1 gi|239756018 PREDICTED: similar to hCG1790963 [Homo sapiens] 30 5.3 gi|239750538 PREDICTED: hypothetical protein XP_002347438 [Homo ... 30 5.3 gi|4507431 thyrotrophic embryonic factor isoform 1 [Homo sapiens] 30 5.3 gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase ... 30 5.3 gi|66932990 folylpolyglutamate synthase isoform b [Homo sapiens] 30 9.1 gi|66932984 folylpolyglutamate synthase isoform a precursor [Hom... 30 9.1 >gi|40316915 arginyl aminopeptidase [Homo sapiens] Length = 650 Score = 1344 bits (3479), Expect = 0.0 Identities = 650/650 (100%), Positives = 650/650 (100%) Query: 1 MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLS 60 MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLS Sbjct: 1 MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLS 60 Query: 61 GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ 120 GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ Sbjct: 61 GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ 120 Query: 121 ALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP 180 ALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP Sbjct: 121 ALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP 180 Query: 181 CFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVS 240 CFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVS Sbjct: 181 CFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVS 240 Query: 241 AEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM 300 AEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM Sbjct: 241 AEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM 300 Query: 301 ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST 360 ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST Sbjct: 301 ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST 360 Query: 361 ILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCF 420 ILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCF Sbjct: 361 ILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCF 420 Query: 421 VSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFD 480 VSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFD Sbjct: 421 VSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFD 480 Query: 481 RWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLD 540 RWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLD Sbjct: 481 RWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLD 540 Query: 541 KILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGK 600 KILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGK Sbjct: 541 KILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGK 600 Query: 601 QKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS 650 QKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS Sbjct: 601 QKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS 650 >gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Homo sapiens] Length = 494 Score = 456 bits (1172), Expect = e-128 Identities = 217/431 (50%), Positives = 293/431 (67%), Gaps = 4/431 (0%) Query: 218 FFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKL 277 F F M P+P+YL+AL GDL A++GPRSRVWAEPCL+ A + +G +E++L+ E+L Sbjct: 15 FHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERL 74 Query: 278 FGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVT 337 +GPY+WGRYD++F+PPSFP MENPCLTF+ +L D L +IHE++HSWFGN VT Sbjct: 75 YGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVIDVIHEVAHSWFGNAVT 134 Query: 338 NANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRV 397 NA W E WL+EG YAQRRI+T +GAA+TCLE A L + M + GE++P++KL+V Sbjct: 135 NATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMKLLGEDSPVSKLQV 194 Query: 398 KIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLD 457 K+EPGV+P N YEKG+CFV YL+ L GD +FD FL+AYV ++KF S++A D LD Sbjct: 195 KLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQDLLD 254 Query: 458 FYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEEL 517 +L +FPELK++ VD G EF+RWLN G P PDLS G SL +P E L QLW AE L Sbjct: 255 SFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQGSSLTRPVEALFQLWTAEPL 314 Query: 518 DMKAIEAVA--ISPWKTYQLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRW 575 D A A A IS W+T+Q FLD++L SPLP V L Y S+ ++ NAE+R+RW Sbjct: 315 DQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAEIRIRW 374 Query: 576 GQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHS 635 QIV++ND+ D +V+ FL +Q + YT+PLY + G+ ++ A E F T +LH Sbjct: 375 LQIVVRNDYYPDLHRVRRFLESQMSRMYTIPLYEDLCTGA--LKSFALEVFYQTQGRLHP 432 Query: 636 NVVNYVQQIVA 646 N+ +QQI++ Sbjct: 433 NLRRAIQQILS 443 >gi|4505029 leukotriene A4 hydrolase [Homo sapiens] Length = 611 Score = 378 bits (970), Expect = e-104 Identities = 226/597 (37%), Positives = 334/597 (55%), Gaps = 36/597 (6%) Query: 21 QAVDVAS-ASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELR 79 + VD S AS HLHL +F R L+GTA L ++ E + L Sbjct: 3 EIVDTCSLASPASVCRTKHLHLRCSVDFT-------RRTLTGTAALTVQSQE-DNLRSLV 54 Query: 80 LDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVL 139 LD+ L + + G E A + S+ G + +S P + + + Sbjct: 55 LDTKD-LTIEKVVIN----GQEVKYA-----LGERQSYKGSPMEISLPIALSKNQEIVIE 104 Query: 140 LTYRVG-EGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVP 198 +++ + + WL PEQT+GK+ P++++Q QA+ RA PC DTP+VK Y+A + VP Sbjct: 105 ISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVP 164 Query: 199 DGFTAVMSA----STWEKRGPNKFFFQMCQ--PIPSYLIALAIGDLVSAEVGPRSRVWAE 252 A+MSA T + P++ ++ Q PIP YLIAL +G L S ++GPR+ VW+E Sbjct: 165 KELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSE 224 Query: 253 PCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCL 312 ++ + E++ E L E L GPYVWG+YDLL +PPSFP+GGMENPCLTFVTP L Sbjct: 225 KEQVEKSAYEFSET-ESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTL 283 Query: 313 LAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEA 372 LAGD+SL++VI HEISHSW GNLVTN W FWLNEG T+Y +R I LFG + A Sbjct: 284 LAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNA 343 Query: 373 ATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQD 432 G L+ + GE +P KL V + +DPD Y+ PYEKGF + YL L+G + Sbjct: 344 LGGWGELQNSVKTFGETHPFTKLVVDL-TDIDPDVAYSSVPYEKGFALLFYLEQLLGGPE 402 Query: 433 QFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYL 492 F FLKAYV +F ++SI DD+ DF YF K +VD++ +++ WL +PG PP Sbjct: 403 IFLGFLKAYVEKFSYKSITTDDWKDFLYSYF----KDKVDVLNQVDWNAWLYSPGLPPIK 458 Query: 493 PDLSPGDSLMKPAEELAQLW-AAEELDMKAIEAVAISPWKTYQLVYFLDKILQKSPLPPG 551 P+ +L L+Q W A+E D+ + A + ++QL FL + LQ++PLP G Sbjct: 459 PNYDM--TLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLG 516 Query: 552 NVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLY 608 ++K++ + Y + + N+E+R RW ++ +++ ++ + QG+ K+T PL+ Sbjct: 517 HIKRMQEVY-NFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLF 572 >gi|24432058 aminopeptidase O [Homo sapiens] Length = 720 Score = 100 bits (248), Expect = 5e-21 Identities = 121/534 (22%), Positives = 209/534 (39%), Gaps = 101/534 (18%) Query: 146 EGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVM 205 EG V W + + +P VYT G + NRA FPC + P + A + F +M Sbjct: 253 EGRSVTWTSDQSG----RPCVYTVGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLM 308 Query: 206 SAST-------WEKRGPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAE-PCLID 257 S WE+ ++ M P ++ IA+ + E + + E P Sbjct: 309 SGENSAKPTQLWEECSSWYYYVTMPMPASTFTIAVGCWTEMKMETWSSNDLATERPFSPS 368 Query: 258 AAKEEYNGV---------IEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFV 308 A + GV + AT +++ V+ P G + L + Sbjct: 369 EANFRHVGVCSHMEYPCRFQNASATTQEIIPHRVFA--------PVCLTGACQETLLRLI 420 Query: 309 TPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYT 368 PCL A +HS G + R+ ++ A + Sbjct: 421 PPCLSA-------------AHSVLG------------------AHPFSRLDVLIVPANFP 449 Query: 369 CLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLV 428 L A R D TG + +K G++P+ + + Y KG+ + +LA + Sbjct: 450 SLGMA------RPSKDKTGHTSDSGASVIK--HGLNPEKIFMQVHYLKGYFLLRFLAKRL 501 Query: 429 GDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGW 488 GD+ F SFL+ +VH F + IL+ DFL LE PE +KR+++ + WL + G Sbjct: 502 GDETYF-SFLRKFVHTFHGQLILSQDFLQMLLENIPE--EKRLELSVENIYQDWLESSGI 558 Query: 489 PPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAIS--PWKTY------------- 533 P L + A+ A ++ + + + ++ P K Sbjct: 559 P---------KPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREKEEVFEKLLP 609 Query: 534 -QLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVK 592 QLV L+ +L++ L P ++ L TY ++AE+R RW ++++K+ + + V+ Sbjct: 610 DQLVLLLEHLLEQKTLSPRTLQSLQRTYH--LQDQDAEVRHRWCELIVKHKFTKAYKSVE 667 Query: 593 EFLHNQGKQKYTLPLYHAMMGGSEV-AQTLAKETFASTASQLHSNVVNYVQQIV 645 FL Q Q + LY +M + Q LA+ F T Q+ + V +++ Sbjct: 668 RFL--QEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEML 719 >gi|157266300 membrane alanine aminopeptidase precursor [Homo sapiens] Length = 967 Score = 97.1 bits (240), Expect = 5e-20 Identities = 97/368 (26%), Positives = 151/368 (41%), Gaps = 43/368 (11%) Query: 162 KKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGP------ 215 +K TQ QA R FPCFD PA+K +++ + P TA+ S +GP Sbjct: 204 RKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTAL---SNMLPKGPSTPLPE 260 Query: 216 ----NKFFFQMCQPIPSYLIALAIGDL----VSAEVGPRSRVWAEPCLIDAAKEEY---- 263 N F + +YL+A + + A G R+WA P I A +Y Sbjct: 261 DPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNV 320 Query: 264 NGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLL--------A 314 G I F A PY + D + +P F G MEN +T+ LL + Sbjct: 321 TGPILNFFAGHYDT--PYPLPKSDQIGLP-DFNAGAMENWGLVTYRENSLLFDPLSSSSS 377 Query: 315 GDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAAT 374 + VI HE++H WFGNLVT W + WLNEGF Y + + + + Sbjct: 378 NKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVE-YLGADYAEPTWNLKDLMV 436 Query: 375 GRALLR-QHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQ 433 + R +D +PL+ +I + ++ Y KG + L+ + +D Sbjct: 437 LNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFL-SEDV 495 Query: 434 FDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFD---RWLNTPGWPP 490 F L +Y+H F +++ + +L+ + ++ E R +P D RW G+P Sbjct: 496 FKQGLASYLHTFAYQNTI---YLNLW-DHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPV 551 Query: 491 YLPDLSPG 498 D S G Sbjct: 552 ITVDTSTG 559 >gi|94818891 type 1 tumor necrosis factor receptor shedding aminopeptidase regulator isoform b [Homo sapiens] Length = 941 Score = 95.1 bits (235), Expect = 2e-19 Identities = 110/443 (24%), Positives = 178/443 (40%), Gaps = 56/443 (12%) Query: 61 GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ 120 GT +++ +P + + L SH L+++ A LR+ E EP+ P + Sbjct: 78 GTTKVEITASQP--TSTIILHSHH-LQISRATLRKG--AGERLSEEPLQVLEHPRQ---E 129 Query: 121 ALCVSFPQPCRAAERLQVLLTY--RVGEGPGVCWLAPEQTA-GKKKPFVYTQGQAVLNRA 177 + + P+P V++ Y + E + + +T G+ + TQ + R Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARM 189 Query: 178 FFPCFDTPAVKYKYSALIEVPDGFTAVMSA----STWEKRGPNKFFFQMCQPIPSYLIAL 233 FPCFD PA K +S I A+ + S G + F + + +YL+A Sbjct: 190 AFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAF 249 Query: 234 AIGDLVSA----EVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFG-PYVWGRYDL 288 I D S + G + V+A P I+ A + + L E F PY + DL Sbjct: 250 IISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVT-LLEFYEDYFSIPYPLPKQDL 308 Query: 289 LFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADV---------IIHEISHSWFGNLVTNA 339 +P F G MEN LT L D + + HE++H WFGNLVT Sbjct: 309 AAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTME 367 Query: 340 NWGEFWLNEGFTMY----------AQRRISTILFGAAYTCLEAATGRALLRQHMDITGEE 389 W + WLNEGF + + ++ FG C +A AL H T E Sbjct: 368 WWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFG---KCFDAMEVDALNSSHPVSTPVE 424 Query: 390 NPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRS 449 NP ++R + +++ Y+KG C ++ L + D F S + Y+ + +++ Sbjct: 425 NPA-QIR----------EMFDDVSYDKGACILNMLREYL-SADAFKSGIVQYLQKHSYKN 472 Query: 450 ILADDFLDFYLEYFPELKKKRVD 472 +D D P K +D Sbjct: 473 TKNEDLWDSMASICPTDGVKGMD 495 >gi|94818901 type 1 tumor necrosis factor receptor shedding aminopeptidase regulator isoform a [Homo sapiens] Length = 948 Score = 95.1 bits (235), Expect = 2e-19 Identities = 110/443 (24%), Positives = 178/443 (40%), Gaps = 56/443 (12%) Query: 61 GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ 120 GT +++ +P + + L SH L+++ A LR+ E EP+ P + Sbjct: 78 GTTKVEITASQP--TSTIILHSHH-LQISRATLRKG--AGERLSEEPLQVLEHPRQ---E 129 Query: 121 ALCVSFPQPCRAAERLQVLLTY--RVGEGPGVCWLAPEQTA-GKKKPFVYTQGQAVLNRA 177 + + P+P V++ Y + E + + +T G+ + TQ + R Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARM 189 Query: 178 FFPCFDTPAVKYKYSALIEVPDGFTAVMSA----STWEKRGPNKFFFQMCQPIPSYLIAL 233 FPCFD PA K +S I A+ + S G + F + + +YL+A Sbjct: 190 AFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAF 249 Query: 234 AIGDLVSA----EVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFG-PYVWGRYDL 288 I D S + G + V+A P I+ A + + L E F PY + DL Sbjct: 250 IISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVT-LLEFYEDYFSIPYPLPKQDL 308 Query: 289 LFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADV---------IIHEISHSWFGNLVTNA 339 +P F G MEN LT L D + + HE++H WFGNLVT Sbjct: 309 AAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTME 367 Query: 340 NWGEFWLNEGFTMY----------AQRRISTILFGAAYTCLEAATGRALLRQHMDITGEE 389 W + WLNEGF + + ++ FG C +A AL H T E Sbjct: 368 WWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFG---KCFDAMEVDALNSSHPVSTPVE 424 Query: 390 NPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRS 449 NP ++R + +++ Y+KG C ++ L + D F S + Y+ + +++ Sbjct: 425 NPA-QIR----------EMFDDVSYDKGACILNMLREYL-SADAFKSGIVQYLQKHSYKN 472 Query: 450 ILADDFLDFYLEYFPELKKKRVD 472 +D D P K +D Sbjct: 473 TKNEDLWDSMASICPTDGVKGMD 495 >gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens] Length = 1025 Score = 92.0 bits (227), Expect = 1e-18 Identities = 109/436 (25%), Positives = 177/436 (40%), Gaps = 49/436 (11%) Query: 52 PGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFY 111 P S G+ + ++ L+ L H VT + S+E AE + + Sbjct: 183 PNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSA----VSSQEKQAEILEY- 237 Query: 112 TQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGP---GVCWLAPEQTAGKKKPFVYT 168 +++GQ V+ P+ A + + Y G + + +KK F T Sbjct: 238 ----AYHGQIAIVA-PEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAAT 292 Query: 169 QGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMS----ASTWEKRGPNKFFFQMCQ 224 Q + + R+ FPCFD PA K + I + +TA+ + +S G + F Sbjct: 293 QFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQDEFSESV 352 Query: 225 PIPSYLIALAIGDL--VSAEV-GPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKL---F 278 + +YL+A +G++ +S +V G ++A P E G + L T KL F Sbjct: 353 KMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVP--------EKIGQVHYALETTVKLLEFF 404 Query: 279 GPYVWGRYDL----LFMPPSFPFGGMEN-PCLTFVTPCLL--AGDRSLAD------VIIH 325 Y +Y L L P F G MEN LTF LL + S+AD +I H Sbjct: 405 QNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAH 464 Query: 326 EISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDI 385 E++H WFGNLVT W + WLNEGF + + +F + E D Sbjct: 465 ELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIF-KELSSYEDFLDARFKTMKKDS 523 Query: 386 TGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEF 445 +P++ ++ ++ ++ Y KG + L + +D F + Y+H Sbjct: 524 LNSSHPISS---SVQSSEQIEEMFDSLSYFKGSSLLLMLKTYL-SEDVFQHAVVLYLHNH 579 Query: 446 KFRSILADDFLDFYLE 461 + SI +DD D + E Sbjct: 580 SYASIQSDDLWDSFNE 595 >gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens] Length = 1011 Score = 92.0 bits (227), Expect = 1e-18 Identities = 109/436 (25%), Positives = 177/436 (40%), Gaps = 49/436 (11%) Query: 52 PGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFY 111 P S G+ + ++ L+ L H VT + S+E AE + + Sbjct: 169 PNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSA----VSSQEKQAEILEY- 223 Query: 112 TQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGP---GVCWLAPEQTAGKKKPFVYT 168 +++GQ V+ P+ A + + Y G + + +KK F T Sbjct: 224 ----AYHGQIAIVA-PEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAAT 278 Query: 169 QGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMS----ASTWEKRGPNKFFFQMCQ 224 Q + + R+ FPCFD PA K + I + +TA+ + +S G + F Sbjct: 279 QFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQDEFSESV 338 Query: 225 PIPSYLIALAIGDL--VSAEV-GPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKL---F 278 + +YL+A +G++ +S +V G ++A P E G + L T KL F Sbjct: 339 KMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVP--------EKIGQVHYALETTVKLLEFF 390 Query: 279 GPYVWGRYDL----LFMPPSFPFGGMEN-PCLTFVTPCLL--AGDRSLAD------VIIH 325 Y +Y L L P F G MEN LTF LL + S+AD +I H Sbjct: 391 QNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAH 450 Query: 326 EISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDI 385 E++H WFGNLVT W + WLNEGF + + +F + E D Sbjct: 451 ELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIF-KELSSYEDFLDARFKTMKKDS 509 Query: 386 TGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEF 445 +P++ ++ ++ ++ Y KG + L + +D F + Y+H Sbjct: 510 LNSSHPISS---SVQSSEQIEEMFDSLSYFKGSSLLLMLKTYL-SEDVFQHAVVLYLHNH 565 Query: 446 KFRSILADDFLDFYLE 461 + SI +DD D + E Sbjct: 566 SYASIQSDDLWDSFNE 581 >gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] Length = 960 Score = 87.8 bits (216), Expect = 3e-17 Identities = 99/393 (25%), Positives = 165/393 (41%), Gaps = 37/393 (9%) Query: 86 LEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTY--R 143 LE+T A L+ E P + + + P +H AL V P+ + V + + + Sbjct: 115 LEITNATLQSEEDSRYMKPGKELKVLSYP-AHEQIALLV--PEKLTPHLKYYVAMDFQAK 171 Query: 144 VGEGPGVCWLAPEQT-AGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFT 202 +G+G + + +T G+ + T + R FPCFD P K +S I Sbjct: 172 LGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHI 231 Query: 203 AVMS---ASTWEKRGPN-KFFFQMCQPIPSYLIALAIGDLVS----AEVGPRSRVWAEPC 254 A+ + T E G + F+ + +YL+A + D S G + ++A P Sbjct: 232 ALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPD 291 Query: 255 LIDAAKEEYNGVIEEFLATGEKLFGPYV-WGRYDLLFMPPSFPFGGMEN-PCLTFVTPCL 312 + ++ L EK F Y + DL+ +P P G MEN +T+ L Sbjct: 292 KRNQTHYALQASLK-LLDFYEKYFDIYYPLSKLDLIAIPDFAP-GAMENWGLITYRETSL 349 Query: 313 LAGDRS--------LADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFG 364 L ++ + VI HE++H WFGNLVT W + WL EGF Y + L Sbjct: 350 LFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYME------LIA 403 Query: 365 AAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDP---DDTYNETPYEKGFCFV 421 T E L ++ +++ LN R +P P + ++E Y KG C + Sbjct: 404 VNATYPELQFDDYFLNVCFEVITKDS-LNSSRPISKPAETPTQIQEMFDEVSYNKGACIL 462 Query: 422 SYLAHLVGDQDQFDSFLKAYVHEFKFRSILADD 454 + L +G +++F + Y+ +F +R+ DD Sbjct: 463 NMLKDFLG-EEKFQKGIIQYLKKFSYRNAKNDD 494 >gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] Length = 960 Score = 87.8 bits (216), Expect = 3e-17 Identities = 99/393 (25%), Positives = 165/393 (41%), Gaps = 37/393 (9%) Query: 86 LEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTY--R 143 LE+T A L+ E P + + + P +H AL V P+ + V + + + Sbjct: 115 LEITNATLQSEEDSRYMKPGKELKVLSYP-AHEQIALLV--PEKLTPHLKYYVAMDFQAK 171 Query: 144 VGEGPGVCWLAPEQT-AGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFT 202 +G+G + + +T G+ + T + R FPCFD P K +S I Sbjct: 172 LGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHI 231 Query: 203 AVMS---ASTWEKRGPN-KFFFQMCQPIPSYLIALAIGDLVS----AEVGPRSRVWAEPC 254 A+ + T E G + F+ + +YL+A + D S G + ++A P Sbjct: 232 ALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPD 291 Query: 255 LIDAAKEEYNGVIEEFLATGEKLFGPYV-WGRYDLLFMPPSFPFGGMEN-PCLTFVTPCL 312 + ++ L EK F Y + DL+ +P P G MEN +T+ L Sbjct: 292 KRNQTHYALQASLK-LLDFYEKYFDIYYPLSKLDLIAIPDFAP-GAMENWGLITYRETSL 349 Query: 313 LAGDRS--------LADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFG 364 L ++ + VI HE++H WFGNLVT W + WL EGF Y + L Sbjct: 350 LFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYME------LIA 403 Query: 365 AAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDP---DDTYNETPYEKGFCFV 421 T E L ++ +++ LN R +P P + ++E Y KG C + Sbjct: 404 VNATYPELQFDDYFLNVCFEVITKDS-LNSSRPISKPAETPTQIQEMFDEVSYNKGACIL 462 Query: 422 SYLAHLVGDQDQFDSFLKAYVHEFKFRSILADD 454 + L +G +++F + Y+ +F +R+ DD Sbjct: 463 NMLKDFLG-EEKFQKGIIQYLKKFSYRNAKNDD 494 >gi|194239713 laeverin [Homo sapiens] Length = 990 Score = 82.0 bits (201), Expect = 2e-15 Identities = 121/508 (23%), Positives = 201/508 (39%), Gaps = 60/508 (11%) Query: 37 LHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRE 96 LH L+L + P AGS +G + +RC A RL H + A R Sbjct: 105 LHYDLELWPQLRPDELPAGSLPFTGRVNITVRCT----VATSRLLLHSLFQDCERAEVRG 160 Query: 97 --RPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTYR------VGEGP 148 PG+ V F+ + + + +P + ++ L++ + EG Sbjct: 161 PLSPGTGNATVGRVPVDDVWFALDTEYMVLELSEPLKPGSSYELQLSFSGLVKEDLREG- 219 Query: 149 GVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAV---- 204 +L G+++ + +Q + R FPCFD PA+K ++ + + A+ Sbjct: 220 --LFLNVYTDQGERRALLASQLEPTFARYVFPCFDEPALKATFNITMIHHPSYVALSNMP 277 Query: 205 -MSASTWEKRGPNKFF---FQMCQPIPSYLIALAIGD---LVSAEVGPRSRVWAEPCLID 257 + S E +K+ F +P+YL+A I D + E G R+WA I Sbjct: 278 KLGQSEKEDVNGSKWTVTTFSTTPHMPTYLVAFVICDYDHVNRTERGKEIRIWARKDAIA 337 Query: 258 AAKEEY----NGVIEEFLATGEKLFG-PYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPC 311 ++ G I FL E LF Y + D++ +P SF MEN + F Sbjct: 338 NGSADFALNITGPIFSFL---EDLFNISYSLPKTDIIALP-SFDNHAMENWGLMIFDESG 393 Query: 312 LLAGDRS--------LADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILF 363 LL + ++ V+ HEI H WFGNLVT W WLNEGF Y + + F Sbjct: 394 LLLEPKDQLTEKKTLISYVVSHEIGHQWFGNLVTMNWWNNIWLNEGFASYFEFEVIN-YF 452 Query: 364 GAAYTCLEAATGRALLRQHMDITGEENPL--NKLRVKIE--PGVDPDDTYNETPYEKGFC 419 E L +I E++ L + +K+E + + ++ Y KG Sbjct: 453 NPKLPRNEIFFSNIL----HNILREDHALVTRAVAMKVENFKTSEIQELFDIFTYSKGAS 508 Query: 420 FVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGF-- 477 L+ + ++ F S LK+Y+ F + + D D + + + + I+P Sbjct: 509 MARMLSCFL-NEHLFVSALKSYLKTFSYSNAEQD---DLWRHFQMAIDDQSTVILPATIK 564 Query: 478 -EFDRWLNTPGWPPYLPDLSPGDSLMKP 504 D W + G+P ++S G +P Sbjct: 565 NIMDSWTHQSGFPVITLNVSTGVMKQEP 592 >gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens] Length = 919 Score = 82.0 bits (201), Expect = 2e-15 Identities = 74/315 (23%), Positives = 132/315 (41%), Gaps = 24/315 (7%) Query: 159 AGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRG-PN- 216 +G+ + TQ +A R FPC+D PA+K + + VP A+ + + +++ P+ Sbjct: 168 SGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDD 227 Query: 217 ----KFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLA 272 + F + +YL+A +G+ E + V E+ +E Sbjct: 228 ENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAK 287 Query: 273 T----GEKLFGPYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLLAGDRS--------L 319 T + PY + DL+ + F G MEN +T+ LL ++ + Sbjct: 288 TLPFYKDYFNVPYPLPKIDLIAIA-DFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWV 346 Query: 320 ADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALL 379 A V+ HE++H WFGNLVT W WLNEGF + + F + + Sbjct: 347 ALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTR 406 Query: 380 RQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLK 439 Q +D +P + V + + D+ ++ Y KG + L +GD+D F + Sbjct: 407 AQELDALDNSHP---IEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKD-FKKGMN 462 Query: 440 AYVHEFKFRSILADD 454 Y+ +F+ ++ +D Sbjct: 463 MYLTKFQQKNAATED 477 >gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo sapiens] Length = 1024 Score = 79.7 bits (195), Expect = 8e-15 Identities = 86/351 (24%), Positives = 147/351 (41%), Gaps = 30/351 (8%) Query: 160 GKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAV----MSASTWEKRGP 215 G+++ TQ R FPCFD P K + I+ + ++ + S +E+ G Sbjct: 257 GERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEEDGW 316 Query: 216 NKFFFQMCQPIPSYLIALAIGDLVSAEVGPRS----RVWAEPCLIDAAKEEYN-GVIEEF 270 F + +Y +A AI + E +S R++A P I +Y + + Sbjct: 317 VTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRL 376 Query: 271 LATGEKLFG-PYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLAD-------- 321 + E F PY + DLL +P P+ MEN L+ + D S++ Sbjct: 377 IEFYEDYFKVPYSLPKLDLLAVP-KHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVT 435 Query: 322 -VIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLR 380 VI+HEI H WFG+LVT W + WL EGF Y + + T + + +L Sbjct: 436 MVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFE-FVGTDYLYPGWNMEKQRFLTDVLH 494 Query: 381 QHMDITG--EENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFL 438 + M + G +P+++ ++ D D ++ Y+KG + LA+ +G F L Sbjct: 495 EVMLLDGLASSHPVSQ---EVLQATDIDRVFDWIAYKKGAALIRMLANFMG-HSVFQRGL 550 Query: 439 KAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWP 489 + Y+ K+ + +D + E LK+ + D+W G+P Sbjct: 551 QDYLTIHKYGNAARNDLWNTLSE---ALKRNGKYVNIQEVMDQWTLQMGYP 598 >gi|132814467 glutamyl aminopeptidase [Homo sapiens] Length = 957 Score = 75.9 bits (185), Expect = 1e-13 Identities = 82/350 (23%), Positives = 137/350 (39%), Gaps = 36/350 (10%) Query: 160 GKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPN--- 216 G+ K V T + R FPCFD P K Y+ I P + A+ + ++ + Sbjct: 212 GQVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKW 271 Query: 217 -KFFFQMCQPIPSYLIALAIGDLVSAE----VGPRSRVWAEPCLIDAAKEEYNGVIEEFL 271 + F+ P+ +YL+ A+ S + G ++ +P A+ N F Sbjct: 272 TRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFD 331 Query: 272 ATGEKLFGPYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLL--------AGDRSLADV 322 E Y + D + +P F G MEN +T+ LL + + +A V Sbjct: 332 YFEEYFAMNYSLPKLDKIAIP-DFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATV 390 Query: 323 IIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQH 382 + HE+ H WFGN+VT W + WLNEGF + + G + + +L + Sbjct: 391 VAHELVHQWFGNIVTMDWWEDLWLNEGFASFFE------FLGVNHAETDWQMRDQMLLED 444 Query: 383 MDITGEENPLNKLRVKIEPGVDPDD---TYNETPYEKGFCFVSYLAHLVGDQDQFDSFLK 439 + E++ L I PD+ ++ Y KG + L + + F + Sbjct: 445 VLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWI-KPENFQKGCQ 503 Query: 440 AYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWP 489 Y+ +++F++ DF LE L K V D W G+P Sbjct: 504 MYLEKYQFKNAKTSDFW-AALEEASRLPVKEV-------MDTWTRQMGYP 545 >gi|239754599 PREDICTED: hypothetical protein [Homo sapiens] Length = 294 Score = 32.0 bits (71), Expect = 1.8 Identities = 42/128 (32%), Positives = 48/128 (37%), Gaps = 31/128 (24%) Query: 18 HSAQAVDVASASNFRAFELLHLH--LDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGA 75 HSA A A+N A ELL L L RA GP A L RC+ P A Sbjct: 23 HSALGAQPAQAANGDADELLELSALLQPRAGRGP------------CATLSGRCITP--A 68 Query: 76 AELRLDSH----PCLEVTAAALRRERPG----SEEPPAE-------PVSFYTQPFSHYGQ 120 L L SH C + A A PG +EPP+ P Q S G Sbjct: 69 TALLLLSHRLRAQCRPMQATAAEAGSPGLGRLGKEPPSRESWTGSAPRRCPCQDASRAGS 128 Query: 121 ALCVSFPQ 128 +C S PQ Sbjct: 129 GVCRSRPQ 136 >gi|42475941 zinc finger protein 261 [Homo sapiens] Length = 1370 Score = 32.0 bits (71), Expect = 1.8 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 5/80 (6%) Query: 46 EFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTA-AALRRERPGSEE-- 102 E PP PGAG+ S +L+ L P+ L+ E T+ A RR PG EE Sbjct: 122 EVVPPDPGAGANSCSPEGLLE--PLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEEL 179 Query: 103 PPAEPVSFYTQPFSHYGQAL 122 P +P S P G+ L Sbjct: 180 PQGQPQSPNAPPSPSVGETL 199 >gi|4827067 zinc finger protein 261 [Homo sapiens] Length = 1370 Score = 32.0 bits (71), Expect = 1.8 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 5/80 (6%) Query: 46 EFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTA-AALRRERPGSEE-- 102 E PP PGAG+ S +L+ L P+ L+ E T+ A RR PG EE Sbjct: 122 EVVPPDPGAGANSCSPEGLLE--PLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEEL 179 Query: 103 PPAEPVSFYTQPFSHYGQAL 122 P +P S P G+ L Sbjct: 180 PQGQPQSPNAPPSPSVGETL 199 >gi|219273466 hypothetical protein LOC29125 [Homo sapiens] Length = 178 Score = 31.2 bits (69), Expect = 3.1 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 1/64 (1%) Query: 50 PGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCL-EVTAAALRRERPGSEEPPAEPV 108 PG G G G G L L L+ GA E L+ HP L + +A+ R S + EP Sbjct: 22 PGVGCGGDGARGGGELSLSNLDLPGAGEAGLEHHPLLGHLFISAVPRWPHLSSQSGVEPP 81 Query: 109 SFYT 112 +T Sbjct: 82 DRWT 85 >gi|94536786 hypothetical protein LOC79091 [Homo sapiens] Length = 404 Score = 31.2 bits (69), Expect = 3.1 Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 7/66 (10%) Query: 49 PPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPV 108 PPG G G+ G S A D E AE +LD L+V +RR R S+ PA P+ Sbjct: 88 PPGSGHGNEGFSLQAGTDTTGQE---VAEAQLDEDGDLDV----VRRPRAASDSNPAGPL 140 Query: 109 SFYTQP 114 P Sbjct: 141 RDKVHP 146 >gi|98986321 gliomedin [Homo sapiens] Length = 551 Score = 31.2 bits (69), Expect = 3.1 Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 12/84 (14%) Query: 57 RGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFS 116 RGLS LR LE + E R DS L A L R G+ PP +P S S Sbjct: 42 RGLSSA----LRALEAQRGREQREDS--ALRSFLAELSRAPRGASAPPQDPASSARNKRS 95 Query: 117 HYGQALCVSFPQPCRAAERLQVLL 140 H G+ P P AE +L+ Sbjct: 96 HSGE------PAPHIRAESHDMLM 113 >gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] Length = 1349 Score = 31.2 bits (69), Expect = 3.1 Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 12/93 (12%) Query: 224 QPIPSYL--IALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPY 281 +P P Y+ + + ++S+ P + P + + E + T P Sbjct: 979 EPPPFYVPEVGSPLSSVMSSPPLPTEGPFGHPTIPEENGENASNSTLPLTQTPTGGRSPE 1038 Query: 282 VWGRYDLLFMPPSFPFGGMENPCLTF---VTPC 311 WGR P FPFGG+E P + F + PC Sbjct: 1039 PWGR-------PEFPFGGLETPAMMFPHQLPPC 1064 >gi|239756018 PREDICTED: similar to hCG1790963 [Homo sapiens] Length = 196 Score = 30.4 bits (67), Expect = 5.3 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 10/103 (9%) Query: 4 GEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTA 63 GE +P P +VA N + E +A GPPGP + S L TA Sbjct: 7 GEGTPARQDLPAPRGYTLTENVARILNRKLLEHAVKEERRQAAHGPPGPHSDSHSLRDTA 66 Query: 64 VLDLRCLEPEGAAELRLDS-HPCLEVTAAALRRERPGSEEPPA 105 EP EL + P LE ++ ERP + PP+ Sbjct: 67 -------EPGAMEELPCSALVPSLETCFSS--SERPANSRPPS 100 >gi|239750538 PREDICTED: hypothetical protein XP_002347438 [Homo sapiens] Length = 196 Score = 30.4 bits (67), Expect = 5.3 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 10/103 (9%) Query: 4 GEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTA 63 GE +P P +VA N + E +A GPPGP + S L TA Sbjct: 7 GEGTPARQDLPAPRGYTLTENVARILNRKLLEHAVKEERRQAAHGPPGPHSDSHSLRDTA 66 Query: 64 VLDLRCLEPEGAAELRLDS-HPCLEVTAAALRRERPGSEEPPA 105 EP EL + P LE ++ ERP + PP+ Sbjct: 67 -------EPGAMEELPCSALVPSLETCFSS--SERPANSRPPS 100 >gi|4507431 thyrotrophic embryonic factor isoform 1 [Homo sapiens] Length = 303 Score = 30.4 bits (67), Expect = 5.3 Identities = 20/42 (47%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Query: 41 LDLRAEFGP-PGPGAGSRGLSGTAVLDLRCLEPEGAAELRLD 81 +D +A GP PG AG RGLSG+ L L+ L E RLD Sbjct: 12 VDPQAGPGPGPGRAAGERGLSGSFPLVLKKLMENPPREARLD 53 >gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 [Homo sapiens] Length = 311 Score = 30.4 bits (67), Expect = 5.3 Identities = 45/158 (28%), Positives = 58/158 (36%), Gaps = 21/158 (13%) Query: 2 ASGEHSPG-------SGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPG--P 52 +S H PG SG RR A V V E L LH D+RA P Sbjct: 37 SSSVHRPGAPGLPLASGPGRRRFPQALIVGVKKGGTRALLEFLRLHPDVRALGSEPHFFD 96 Query: 53 GAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPV--SF 110 RGL+ L R L+ ++ ++ P VT A RR S + V + Sbjct: 97 RCYERGLAWYRSLMPRTLD----GQITMEKTPSYFVTREAPRRIHAMSPDTKLIVVVRNP 152 Query: 111 YTQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGP 148 T+ S Y Q L + P A L +R G GP Sbjct: 153 VTRAISDYAQTLSKTPGLPSFRA------LAFRHGLGP 184 >gi|66932990 folylpolyglutamate synthase isoform b [Homo sapiens] Length = 537 Score = 29.6 bits (65), Expect = 9.1 Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 19/83 (22%) Query: 71 EPEGAAELRLDSHP------------CLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHY 118 EP G+A L L HP C+ + + R +PP+ P T P +H Sbjct: 443 EPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPVAHS 502 Query: 119 GQALCVSFPQPCRAAERLQVLLT 141 G ++ R A + VL+T Sbjct: 503 GASI-------LREAAAIHVLVT 518 >gi|66932984 folylpolyglutamate synthase isoform a precursor [Homo sapiens] Length = 587 Score = 29.6 bits (65), Expect = 9.1 Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 19/83 (22%) Query: 71 EPEGAAELRLDSHP------------CLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHY 118 EP G+A L L HP C+ + + R +PP+ P T P +H Sbjct: 493 EPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPVAHS 552 Query: 119 GQALCVSFPQPCRAAERLQVLLT 141 G ++ R A + VL+T Sbjct: 553 GASI-------LREAAAIHVLVT 568 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.137 0.432 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,405,224 Number of Sequences: 37866 Number of extensions: 1378596 Number of successful extensions: 3129 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 3077 Number of HSP's gapped (non-prelim): 34 length of query: 650 length of database: 18,247,518 effective HSP length: 109 effective length of query: 541 effective length of database: 14,120,124 effective search space: 7638987084 effective search space used: 7638987084 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.