Guide to the Human Genome
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Search of human proteins with 40316915

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40316915 arginyl aminopeptidase [Homo sapiens]
         (650 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40316915 arginyl aminopeptidase [Homo sapiens]                    1344   0.0  
gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Ho...   456   e-128
gi|4505029 leukotriene A4 hydrolase [Homo sapiens]                    378   e-104
gi|24432058 aminopeptidase O [Homo sapiens]                           100   5e-21
gi|157266300 membrane alanine aminopeptidase precursor [Homo sap...    97   5e-20
gi|94818891 type 1 tumor necrosis factor receptor shedding amino...    95   2e-19
gi|94818901 type 1 tumor necrosis factor receptor shedding amino...    95   2e-19
gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens]    92   1e-18
gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens]    92   1e-18
gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]     88   3e-17
gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]      88   3e-17
gi|194239713 laeverin [Homo sapiens]                                   82   2e-15
gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens]         82   2e-15
gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo ...    80   8e-15
gi|132814467 glutamyl aminopeptidase [Homo sapiens]                    76   1e-13
gi|239754599 PREDICTED: hypothetical protein [Homo sapiens]            32   1.8  
gi|42475941 zinc finger protein 261 [Homo sapiens]                     32   1.8  
gi|4827067 zinc finger protein 261 [Homo sapiens]                      32   1.8  
gi|219273466 hypothetical protein LOC29125 [Homo sapiens]              31   3.1  
gi|94536786 hypothetical protein LOC79091 [Homo sapiens]               31   3.1  
gi|98986321 gliomedin [Homo sapiens]                                   31   3.1  
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]      31   3.1  
gi|239756018 PREDICTED: similar to hCG1790963 [Homo sapiens]           30   5.3  
gi|239750538 PREDICTED: hypothetical protein XP_002347438 [Homo ...    30   5.3  
gi|4507431 thyrotrophic embryonic factor isoform 1 [Homo sapiens]      30   5.3  
gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase ...    30   5.3  
gi|66932990 folylpolyglutamate synthase isoform b [Homo sapiens]       30   9.1  
gi|66932984 folylpolyglutamate synthase isoform a precursor [Hom...    30   9.1  

>gi|40316915 arginyl aminopeptidase [Homo sapiens]
          Length = 650

 Score = 1344 bits (3479), Expect = 0.0
 Identities = 650/650 (100%), Positives = 650/650 (100%)

Query: 1   MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLS 60
           MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLS
Sbjct: 1   MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLS 60

Query: 61  GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ 120
           GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ
Sbjct: 61  GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ 120

Query: 121 ALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP 180
           ALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP
Sbjct: 121 ALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP 180

Query: 181 CFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVS 240
           CFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVS
Sbjct: 181 CFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVS 240

Query: 241 AEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM 300
           AEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM
Sbjct: 241 AEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM 300

Query: 301 ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST 360
           ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST
Sbjct: 301 ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST 360

Query: 361 ILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCF 420
           ILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCF
Sbjct: 361 ILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCF 420

Query: 421 VSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFD 480
           VSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFD
Sbjct: 421 VSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFD 480

Query: 481 RWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLD 540
           RWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLD
Sbjct: 481 RWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLD 540

Query: 541 KILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGK 600
           KILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGK
Sbjct: 541 KILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGK 600

Query: 601 QKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS 650
           QKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS
Sbjct: 601 QKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS 650


>gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Homo
           sapiens]
          Length = 494

 Score =  456 bits (1172), Expect = e-128
 Identities = 217/431 (50%), Positives = 293/431 (67%), Gaps = 4/431 (0%)

Query: 218 FFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKL 277
           F F M  P+P+YL+AL  GDL  A++GPRSRVWAEPCL+  A  + +G +E++L+  E+L
Sbjct: 15  FHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERL 74

Query: 278 FGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVT 337
           +GPY+WGRYD++F+PPSFP   MENPCLTF+   +L  D  L   +IHE++HSWFGN VT
Sbjct: 75  YGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVIDVIHEVAHSWFGNAVT 134

Query: 338 NANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRV 397
           NA W E WL+EG   YAQRRI+T  +GAA+TCLE A     L + M + GE++P++KL+V
Sbjct: 135 NATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMKLLGEDSPVSKLQV 194

Query: 398 KIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLD 457
           K+EPGV+P    N   YEKG+CFV YL+ L GD  +FD FL+AYV ++KF S++A D LD
Sbjct: 195 KLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQDLLD 254

Query: 458 FYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEEL 517
            +L +FPELK++ VD   G EF+RWLN  G P   PDLS G SL +P E L QLW AE L
Sbjct: 255 SFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQGSSLTRPVEALFQLWTAEPL 314

Query: 518 DMKAIEAVA--ISPWKTYQLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRW 575
           D  A  A A  IS W+T+Q   FLD++L  SPLP   V  L   Y S+ ++ NAE+R+RW
Sbjct: 315 DQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAEIRIRW 374

Query: 576 GQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHS 635
            QIV++ND+  D  +V+ FL +Q  + YT+PLY  +  G+   ++ A E F  T  +LH 
Sbjct: 375 LQIVVRNDYYPDLHRVRRFLESQMSRMYTIPLYEDLCTGA--LKSFALEVFYQTQGRLHP 432

Query: 636 NVVNYVQQIVA 646
           N+   +QQI++
Sbjct: 433 NLRRAIQQILS 443


>gi|4505029 leukotriene A4 hydrolase [Homo sapiens]
          Length = 611

 Score =  378 bits (970), Expect = e-104
 Identities = 226/597 (37%), Positives = 334/597 (55%), Gaps = 36/597 (6%)

Query: 21  QAVDVAS-ASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELR 79
           + VD  S AS        HLHL    +F         R L+GTA L ++  E +    L 
Sbjct: 3   EIVDTCSLASPASVCRTKHLHLRCSVDFT-------RRTLTGTAALTVQSQE-DNLRSLV 54

Query: 80  LDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVL 139
           LD+   L +    +     G E   A       +  S+ G  + +S P      + + + 
Sbjct: 55  LDTKD-LTIEKVVIN----GQEVKYA-----LGERQSYKGSPMEISLPIALSKNQEIVIE 104

Query: 140 LTYRVG-EGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVP 198
           +++    +   + WL PEQT+GK+ P++++Q QA+  RA  PC DTP+VK  Y+A + VP
Sbjct: 105 ISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVP 164

Query: 199 DGFTAVMSA----STWEKRGPNKFFFQMCQ--PIPSYLIALAIGDLVSAEVGPRSRVWAE 252
               A+MSA     T +   P++  ++  Q  PIP YLIAL +G L S ++GPR+ VW+E
Sbjct: 165 KELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSE 224

Query: 253 PCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCL 312
              ++ +  E++   E  L   E L GPYVWG+YDLL +PPSFP+GGMENPCLTFVTP L
Sbjct: 225 KEQVEKSAYEFSET-ESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTL 283

Query: 313 LAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEA 372
           LAGD+SL++VI HEISHSW GNLVTN  W  FWLNEG T+Y +R I   LFG  +    A
Sbjct: 284 LAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNA 343

Query: 373 ATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQD 432
             G   L+  +   GE +P  KL V +   +DPD  Y+  PYEKGF  + YL  L+G  +
Sbjct: 344 LGGWGELQNSVKTFGETHPFTKLVVDL-TDIDPDVAYSSVPYEKGFALLFYLEQLLGGPE 402

Query: 433 QFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYL 492
            F  FLKAYV +F ++SI  DD+ DF   YF    K +VD++   +++ WL +PG PP  
Sbjct: 403 IFLGFLKAYVEKFSYKSITTDDWKDFLYSYF----KDKVDVLNQVDWNAWLYSPGLPPIK 458

Query: 493 PDLSPGDSLMKPAEELAQLW-AAEELDMKAIEAVAISPWKTYQLVYFLDKILQKSPLPPG 551
           P+     +L      L+Q W  A+E D+ +  A  +    ++QL  FL + LQ++PLP G
Sbjct: 459 PNYDM--TLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLG 516

Query: 552 NVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLY 608
           ++K++ + Y + +   N+E+R RW ++ +++  ++      +    QG+ K+T PL+
Sbjct: 517 HIKRMQEVY-NFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLF 572


>gi|24432058 aminopeptidase O [Homo sapiens]
          Length = 720

 Score =  100 bits (248), Expect = 5e-21
 Identities = 121/534 (22%), Positives = 209/534 (39%), Gaps = 101/534 (18%)

Query: 146 EGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVM 205
           EG  V W + +      +P VYT G  + NRA FPC + P     + A +     F  +M
Sbjct: 253 EGRSVTWTSDQSG----RPCVYTVGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLM 308

Query: 206 SAST-------WEKRGPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAE-PCLID 257
           S          WE+     ++  M  P  ++ IA+     +  E    + +  E P    
Sbjct: 309 SGENSAKPTQLWEECSSWYYYVTMPMPASTFTIAVGCWTEMKMETWSSNDLATERPFSPS 368

Query: 258 AAKEEYNGV---------IEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFV 308
            A   + GV          +   AT +++    V+         P    G  +   L  +
Sbjct: 369 EANFRHVGVCSHMEYPCRFQNASATTQEIIPHRVFA--------PVCLTGACQETLLRLI 420

Query: 309 TPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYT 368
            PCL A             +HS  G                   +   R+  ++  A + 
Sbjct: 421 PPCLSA-------------AHSVLG------------------AHPFSRLDVLIVPANFP 449

Query: 369 CLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLV 428
            L  A      R   D TG  +      +K   G++P+  + +  Y KG+  + +LA  +
Sbjct: 450 SLGMA------RPSKDKTGHTSDSGASVIK--HGLNPEKIFMQVHYLKGYFLLRFLAKRL 501

Query: 429 GDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGW 488
           GD+  F SFL+ +VH F  + IL+ DFL   LE  PE  +KR+++     +  WL + G 
Sbjct: 502 GDETYF-SFLRKFVHTFHGQLILSQDFLQMLLENIPE--EKRLELSVENIYQDWLESSGI 558

Query: 489 PPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAIS--PWKTY------------- 533
           P           L +     A+   A ++  +  + + ++  P K               
Sbjct: 559 P---------KPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREKEEVFEKLLP 609

Query: 534 -QLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVK 592
            QLV  L+ +L++  L P  ++ L  TY      ++AE+R RW ++++K+   + +  V+
Sbjct: 610 DQLVLLLEHLLEQKTLSPRTLQSLQRTYH--LQDQDAEVRHRWCELIVKHKFTKAYKSVE 667

Query: 593 EFLHNQGKQKYTLPLYHAMMGGSEV-AQTLAKETFASTASQLHSNVVNYVQQIV 645
            FL  Q  Q   + LY  +M   +   Q LA+  F  T  Q+  +    V +++
Sbjct: 668 RFL--QEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEML 719


>gi|157266300 membrane alanine aminopeptidase precursor [Homo
           sapiens]
          Length = 967

 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 97/368 (26%), Positives = 151/368 (41%), Gaps = 43/368 (11%)

Query: 162 KKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGP------ 215
           +K    TQ QA   R  FPCFD PA+K +++  +  P   TA+   S    +GP      
Sbjct: 204 RKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTAL---SNMLPKGPSTPLPE 260

Query: 216 ----NKFFFQMCQPIPSYLIALAIGDL----VSAEVGPRSRVWAEPCLIDAAKEEY---- 263
               N   F     + +YL+A  + +       A  G   R+WA P  I A   +Y    
Sbjct: 261 DPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNV 320

Query: 264 NGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLL--------A 314
            G I  F A       PY   + D + +P  F  G MEN   +T+    LL        +
Sbjct: 321 TGPILNFFAGHYDT--PYPLPKSDQIGLP-DFNAGAMENWGLVTYRENSLLFDPLSSSSS 377

Query: 315 GDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAAT 374
               +  VI HE++H WFGNLVT   W + WLNEGF  Y +  +        +   +   
Sbjct: 378 NKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVE-YLGADYAEPTWNLKDLMV 436

Query: 375 GRALLR-QHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQ 433
              + R   +D     +PL+    +I       + ++   Y KG   +  L+  +  +D 
Sbjct: 437 LNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFL-SEDV 495

Query: 434 FDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFD---RWLNTPGWPP 490
           F   L +Y+H F +++ +   +L+ + ++  E    R   +P    D   RW    G+P 
Sbjct: 496 FKQGLASYLHTFAYQNTI---YLNLW-DHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPV 551

Query: 491 YLPDLSPG 498
              D S G
Sbjct: 552 ITVDTSTG 559


>gi|94818891 type 1 tumor necrosis factor receptor shedding
           aminopeptidase regulator isoform b [Homo sapiens]
          Length = 941

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 110/443 (24%), Positives = 178/443 (40%), Gaps = 56/443 (12%)

Query: 61  GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ 120
           GT  +++   +P   + + L SH  L+++ A LR+     E    EP+     P     +
Sbjct: 78  GTTKVEITASQP--TSTIILHSHH-LQISRATLRKG--AGERLSEEPLQVLEHPRQ---E 129

Query: 121 ALCVSFPQPCRAAERLQVLLTY--RVGEGPGVCWLAPEQTA-GKKKPFVYTQGQAVLNRA 177
            + +  P+P        V++ Y   + E     + +  +T  G+ +    TQ +    R 
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARM 189

Query: 178 FFPCFDTPAVKYKYSALIEVPDGFTAVMSA----STWEKRGPNKFFFQMCQPIPSYLIAL 233
            FPCFD PA K  +S  I       A+ +     S     G  +  F +   + +YL+A 
Sbjct: 190 AFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAF 249

Query: 234 AIGDLVSA----EVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFG-PYVWGRYDL 288
            I D  S     + G +  V+A P  I+ A    +  +   L   E  F  PY   + DL
Sbjct: 250 IISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVT-LLEFYEDYFSIPYPLPKQDL 308

Query: 289 LFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADV---------IIHEISHSWFGNLVTNA 339
             +P  F  G MEN  LT      L  D   +           + HE++H WFGNLVT  
Sbjct: 309 AAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTME 367

Query: 340 NWGEFWLNEGFTMY----------AQRRISTILFGAAYTCLEAATGRALLRQHMDITGEE 389
            W + WLNEGF  +           + ++    FG    C +A    AL   H   T  E
Sbjct: 368 WWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFG---KCFDAMEVDALNSSHPVSTPVE 424

Query: 390 NPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRS 449
           NP  ++R          + +++  Y+KG C ++ L   +   D F S +  Y+ +  +++
Sbjct: 425 NPA-QIR----------EMFDDVSYDKGACILNMLREYL-SADAFKSGIVQYLQKHSYKN 472

Query: 450 ILADDFLDFYLEYFPELKKKRVD 472
              +D  D      P    K +D
Sbjct: 473 TKNEDLWDSMASICPTDGVKGMD 495


>gi|94818901 type 1 tumor necrosis factor receptor shedding
           aminopeptidase regulator isoform a [Homo sapiens]
          Length = 948

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 110/443 (24%), Positives = 178/443 (40%), Gaps = 56/443 (12%)

Query: 61  GTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQ 120
           GT  +++   +P   + + L SH  L+++ A LR+     E    EP+     P     +
Sbjct: 78  GTTKVEITASQP--TSTIILHSHH-LQISRATLRKG--AGERLSEEPLQVLEHPRQ---E 129

Query: 121 ALCVSFPQPCRAAERLQVLLTY--RVGEGPGVCWLAPEQTA-GKKKPFVYTQGQAVLNRA 177
            + +  P+P        V++ Y   + E     + +  +T  G+ +    TQ +    R 
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARM 189

Query: 178 FFPCFDTPAVKYKYSALIEVPDGFTAVMSA----STWEKRGPNKFFFQMCQPIPSYLIAL 233
            FPCFD PA K  +S  I       A+ +     S     G  +  F +   + +YL+A 
Sbjct: 190 AFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAF 249

Query: 234 AIGDLVSA----EVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFG-PYVWGRYDL 288
            I D  S     + G +  V+A P  I+ A    +  +   L   E  F  PY   + DL
Sbjct: 250 IISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVT-LLEFYEDYFSIPYPLPKQDL 308

Query: 289 LFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADV---------IIHEISHSWFGNLVTNA 339
             +P  F  G MEN  LT      L  D   +           + HE++H WFGNLVT  
Sbjct: 309 AAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTME 367

Query: 340 NWGEFWLNEGFTMY----------AQRRISTILFGAAYTCLEAATGRALLRQHMDITGEE 389
            W + WLNEGF  +           + ++    FG    C +A    AL   H   T  E
Sbjct: 368 WWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFG---KCFDAMEVDALNSSHPVSTPVE 424

Query: 390 NPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRS 449
           NP  ++R          + +++  Y+KG C ++ L   +   D F S +  Y+ +  +++
Sbjct: 425 NPA-QIR----------EMFDDVSYDKGACILNMLREYL-SADAFKSGIVQYLQKHSYKN 472

Query: 450 ILADDFLDFYLEYFPELKKKRVD 472
              +D  D      P    K +D
Sbjct: 473 TKNEDLWDSMASICPTDGVKGMD 495


>gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens]
          Length = 1025

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 109/436 (25%), Positives = 177/436 (40%), Gaps = 49/436 (11%)

Query: 52  PGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFY 111
           P   S    G+  + ++ L+      L    H    VT  +       S+E  AE + + 
Sbjct: 183 PNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSA----VSSQEKQAEILEY- 237

Query: 112 TQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGP---GVCWLAPEQTAGKKKPFVYT 168
               +++GQ   V+ P+   A     + + Y         G    +    + +KK F  T
Sbjct: 238 ----AYHGQIAIVA-PEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAAT 292

Query: 169 QGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMS----ASTWEKRGPNKFFFQMCQ 224
           Q + +  R+ FPCFD PA K  +   I   + +TA+ +    +S     G  +  F    
Sbjct: 293 QFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQDEFSESV 352

Query: 225 PIPSYLIALAIGDL--VSAEV-GPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKL---F 278
            + +YL+A  +G++  +S +V G    ++A P        E  G +   L T  KL   F
Sbjct: 353 KMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVP--------EKIGQVHYALETTVKLLEFF 404

Query: 279 GPYVWGRYDL----LFMPPSFPFGGMEN-PCLTFVTPCLL--AGDRSLAD------VIIH 325
             Y   +Y L    L   P F  G MEN   LTF    LL  +   S+AD      +I H
Sbjct: 405 QNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAH 464

Query: 326 EISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDI 385
           E++H WFGNLVT   W + WLNEGF  + +      +F    +  E            D 
Sbjct: 465 ELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIF-KELSSYEDFLDARFKTMKKDS 523

Query: 386 TGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEF 445
               +P++     ++     ++ ++   Y KG   +  L   +  +D F   +  Y+H  
Sbjct: 524 LNSSHPISS---SVQSSEQIEEMFDSLSYFKGSSLLLMLKTYL-SEDVFQHAVVLYLHNH 579

Query: 446 KFRSILADDFLDFYLE 461
            + SI +DD  D + E
Sbjct: 580 SYASIQSDDLWDSFNE 595


>gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens]
          Length = 1011

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 109/436 (25%), Positives = 177/436 (40%), Gaps = 49/436 (11%)

Query: 52  PGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFY 111
           P   S    G+  + ++ L+      L    H    VT  +       S+E  AE + + 
Sbjct: 169 PNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSA----VSSQEKQAEILEY- 223

Query: 112 TQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGP---GVCWLAPEQTAGKKKPFVYT 168
               +++GQ   V+ P+   A     + + Y         G    +    + +KK F  T
Sbjct: 224 ----AYHGQIAIVA-PEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAAT 278

Query: 169 QGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMS----ASTWEKRGPNKFFFQMCQ 224
           Q + +  R+ FPCFD PA K  +   I   + +TA+ +    +S     G  +  F    
Sbjct: 279 QFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQDEFSESV 338

Query: 225 PIPSYLIALAIGDL--VSAEV-GPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKL---F 278
            + +YL+A  +G++  +S +V G    ++A P        E  G +   L T  KL   F
Sbjct: 339 KMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVP--------EKIGQVHYALETTVKLLEFF 390

Query: 279 GPYVWGRYDL----LFMPPSFPFGGMEN-PCLTFVTPCLL--AGDRSLAD------VIIH 325
             Y   +Y L    L   P F  G MEN   LTF    LL  +   S+AD      +I H
Sbjct: 391 QNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAH 450

Query: 326 EISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDI 385
           E++H WFGNLVT   W + WLNEGF  + +      +F    +  E            D 
Sbjct: 451 ELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIF-KELSSYEDFLDARFKTMKKDS 509

Query: 386 TGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEF 445
               +P++     ++     ++ ++   Y KG   +  L   +  +D F   +  Y+H  
Sbjct: 510 LNSSHPISS---SVQSSEQIEEMFDSLSYFKGSSLLLMLKTYL-SEDVFQHAVVLYLHNH 565

Query: 446 KFRSILADDFLDFYLE 461
            + SI +DD  D + E
Sbjct: 566 SYASIQSDDLWDSFNE 581


>gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]
          Length = 960

 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 99/393 (25%), Positives = 165/393 (41%), Gaps = 37/393 (9%)

Query: 86  LEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTY--R 143
           LE+T A L+ E       P + +   + P +H   AL V  P+      +  V + +  +
Sbjct: 115 LEITNATLQSEEDSRYMKPGKELKVLSYP-AHEQIALLV--PEKLTPHLKYYVAMDFQAK 171

Query: 144 VGEGPGVCWLAPEQT-AGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFT 202
           +G+G    + +  +T  G+ +    T  +    R  FPCFD P  K  +S  I       
Sbjct: 172 LGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHI 231

Query: 203 AVMS---ASTWEKRGPN-KFFFQMCQPIPSYLIALAIGDLVS----AEVGPRSRVWAEPC 254
           A+ +     T E  G   +  F+    + +YL+A  + D  S       G +  ++A P 
Sbjct: 232 ALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPD 291

Query: 255 LIDAAKEEYNGVIEEFLATGEKLFGPYV-WGRYDLLFMPPSFPFGGMEN-PCLTFVTPCL 312
             +         ++  L   EK F  Y    + DL+ +P   P G MEN   +T+    L
Sbjct: 292 KRNQTHYALQASLK-LLDFYEKYFDIYYPLSKLDLIAIPDFAP-GAMENWGLITYRETSL 349

Query: 313 LAGDRS--------LADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFG 364
           L   ++        +  VI HE++H WFGNLVT   W + WL EGF  Y +      L  
Sbjct: 350 LFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYME------LIA 403

Query: 365 AAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDP---DDTYNETPYEKGFCFV 421
              T  E       L    ++  +++ LN  R   +P   P    + ++E  Y KG C +
Sbjct: 404 VNATYPELQFDDYFLNVCFEVITKDS-LNSSRPISKPAETPTQIQEMFDEVSYNKGACIL 462

Query: 422 SYLAHLVGDQDQFDSFLKAYVHEFKFRSILADD 454
           + L   +G +++F   +  Y+ +F +R+   DD
Sbjct: 463 NMLKDFLG-EEKFQKGIIQYLKKFSYRNAKNDD 494


>gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]
          Length = 960

 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 99/393 (25%), Positives = 165/393 (41%), Gaps = 37/393 (9%)

Query: 86  LEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTY--R 143
           LE+T A L+ E       P + +   + P +H   AL V  P+      +  V + +  +
Sbjct: 115 LEITNATLQSEEDSRYMKPGKELKVLSYP-AHEQIALLV--PEKLTPHLKYYVAMDFQAK 171

Query: 144 VGEGPGVCWLAPEQT-AGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFT 202
           +G+G    + +  +T  G+ +    T  +    R  FPCFD P  K  +S  I       
Sbjct: 172 LGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHI 231

Query: 203 AVMS---ASTWEKRGPN-KFFFQMCQPIPSYLIALAIGDLVS----AEVGPRSRVWAEPC 254
           A+ +     T E  G   +  F+    + +YL+A  + D  S       G +  ++A P 
Sbjct: 232 ALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPD 291

Query: 255 LIDAAKEEYNGVIEEFLATGEKLFGPYV-WGRYDLLFMPPSFPFGGMEN-PCLTFVTPCL 312
             +         ++  L   EK F  Y    + DL+ +P   P G MEN   +T+    L
Sbjct: 292 KRNQTHYALQASLK-LLDFYEKYFDIYYPLSKLDLIAIPDFAP-GAMENWGLITYRETSL 349

Query: 313 LAGDRS--------LADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFG 364
           L   ++        +  VI HE++H WFGNLVT   W + WL EGF  Y +      L  
Sbjct: 350 LFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYME------LIA 403

Query: 365 AAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDP---DDTYNETPYEKGFCFV 421
              T  E       L    ++  +++ LN  R   +P   P    + ++E  Y KG C +
Sbjct: 404 VNATYPELQFDDYFLNVCFEVITKDS-LNSSRPISKPAETPTQIQEMFDEVSYNKGACIL 462

Query: 422 SYLAHLVGDQDQFDSFLKAYVHEFKFRSILADD 454
           + L   +G +++F   +  Y+ +F +R+   DD
Sbjct: 463 NMLKDFLG-EEKFQKGIIQYLKKFSYRNAKNDD 494


>gi|194239713 laeverin [Homo sapiens]
          Length = 990

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 121/508 (23%), Positives = 201/508 (39%), Gaps = 60/508 (11%)

Query: 37  LHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRE 96
           LH  L+L  +  P    AGS   +G   + +RC      A  RL  H   +    A  R 
Sbjct: 105 LHYDLELWPQLRPDELPAGSLPFTGRVNITVRCT----VATSRLLLHSLFQDCERAEVRG 160

Query: 97  --RPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTYR------VGEGP 148
              PG+       V      F+   + + +   +P +     ++ L++       + EG 
Sbjct: 161 PLSPGTGNATVGRVPVDDVWFALDTEYMVLELSEPLKPGSSYELQLSFSGLVKEDLREG- 219

Query: 149 GVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAV---- 204
              +L      G+++  + +Q +    R  FPCFD PA+K  ++  +     + A+    
Sbjct: 220 --LFLNVYTDQGERRALLASQLEPTFARYVFPCFDEPALKATFNITMIHHPSYVALSNMP 277

Query: 205 -MSASTWEKRGPNKFF---FQMCQPIPSYLIALAIGD---LVSAEVGPRSRVWAEPCLID 257
            +  S  E    +K+    F     +P+YL+A  I D   +   E G   R+WA    I 
Sbjct: 278 KLGQSEKEDVNGSKWTVTTFSTTPHMPTYLVAFVICDYDHVNRTERGKEIRIWARKDAIA 337

Query: 258 AAKEEY----NGVIEEFLATGEKLFG-PYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPC 311
               ++     G I  FL   E LF   Y   + D++ +P SF    MEN   + F    
Sbjct: 338 NGSADFALNITGPIFSFL---EDLFNISYSLPKTDIIALP-SFDNHAMENWGLMIFDESG 393

Query: 312 LLAGDRS--------LADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILF 363
           LL   +         ++ V+ HEI H WFGNLVT   W   WLNEGF  Y +  +    F
Sbjct: 394 LLLEPKDQLTEKKTLISYVVSHEIGHQWFGNLVTMNWWNNIWLNEGFASYFEFEVIN-YF 452

Query: 364 GAAYTCLEAATGRALLRQHMDITGEENPL--NKLRVKIE--PGVDPDDTYNETPYEKGFC 419
                  E      L     +I  E++ L    + +K+E     +  + ++   Y KG  
Sbjct: 453 NPKLPRNEIFFSNIL----HNILREDHALVTRAVAMKVENFKTSEIQELFDIFTYSKGAS 508

Query: 420 FVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGF-- 477
               L+  + ++  F S LK+Y+  F + +   D   D +  +   +  +   I+P    
Sbjct: 509 MARMLSCFL-NEHLFVSALKSYLKTFSYSNAEQD---DLWRHFQMAIDDQSTVILPATIK 564

Query: 478 -EFDRWLNTPGWPPYLPDLSPGDSLMKP 504
              D W +  G+P    ++S G    +P
Sbjct: 565 NIMDSWTHQSGFPVITLNVSTGVMKQEP 592


>gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens]
          Length = 919

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 74/315 (23%), Positives = 132/315 (41%), Gaps = 24/315 (7%)

Query: 159 AGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRG-PN- 216
           +G+ +    TQ +A   R  FPC+D PA+K  +   + VP    A+ + +  +++  P+ 
Sbjct: 168 SGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDD 227

Query: 217 ----KFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLA 272
               +  F     + +YL+A  +G+    E   +  V           E+    +E    
Sbjct: 228 ENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAK 287

Query: 273 T----GEKLFGPYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLLAGDRS--------L 319
           T     +    PY   + DL+ +   F  G MEN   +T+    LL   ++        +
Sbjct: 288 TLPFYKDYFNVPYPLPKIDLIAIA-DFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWV 346

Query: 320 ADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALL 379
           A V+ HE++H WFGNLVT   W   WLNEGF  + +       F       +  +     
Sbjct: 347 ALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTR 406

Query: 380 RQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLK 439
            Q +D     +P   + V +    + D+ ++   Y KG   +  L   +GD+D F   + 
Sbjct: 407 AQELDALDNSHP---IEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKD-FKKGMN 462

Query: 440 AYVHEFKFRSILADD 454
            Y+ +F+ ++   +D
Sbjct: 463 MYLTKFQQKNAATED 477


>gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo
           sapiens]
          Length = 1024

 Score = 79.7 bits (195), Expect = 8e-15
 Identities = 86/351 (24%), Positives = 147/351 (41%), Gaps = 30/351 (8%)

Query: 160 GKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAV----MSASTWEKRGP 215
           G+++    TQ      R  FPCFD P  K  +   I+    + ++    +  S +E+ G 
Sbjct: 257 GERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEEDGW 316

Query: 216 NKFFFQMCQPIPSYLIALAIGDLVSAEVGPRS----RVWAEPCLIDAAKEEYN-GVIEEF 270
               F     + +Y +A AI +    E   +S    R++A P  I     +Y   + +  
Sbjct: 317 VTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRL 376

Query: 271 LATGEKLFG-PYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLAD-------- 321
           +   E  F  PY   + DLL +P   P+  MEN  L+      +  D S++         
Sbjct: 377 IEFYEDYFKVPYSLPKLDLLAVP-KHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVT 435

Query: 322 -VIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLR 380
            VI+HEI H WFG+LVT   W + WL EGF  Y +  + T      +   +      +L 
Sbjct: 436 MVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFE-FVGTDYLYPGWNMEKQRFLTDVLH 494

Query: 381 QHMDITG--EENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFL 438
           + M + G    +P+++   ++    D D  ++   Y+KG   +  LA+ +G    F   L
Sbjct: 495 EVMLLDGLASSHPVSQ---EVLQATDIDRVFDWIAYKKGAALIRMLANFMG-HSVFQRGL 550

Query: 439 KAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWP 489
           + Y+   K+ +   +D  +   E    LK+    +      D+W    G+P
Sbjct: 551 QDYLTIHKYGNAARNDLWNTLSE---ALKRNGKYVNIQEVMDQWTLQMGYP 598


>gi|132814467 glutamyl aminopeptidase [Homo sapiens]
          Length = 957

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 82/350 (23%), Positives = 137/350 (39%), Gaps = 36/350 (10%)

Query: 160 GKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPN--- 216
           G+ K  V T  +    R  FPCFD P  K  Y+  I  P  + A+ +    ++   +   
Sbjct: 212 GQVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKW 271

Query: 217 -KFFFQMCQPIPSYLIALAIGDLVSAE----VGPRSRVWAEPCLIDAAKEEYNGVIEEFL 271
            +  F+   P+ +YL+  A+    S +     G    ++ +P     A+   N     F 
Sbjct: 272 TRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFD 331

Query: 272 ATGEKLFGPYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLL--------AGDRSLADV 322
              E     Y   + D + +P  F  G MEN   +T+    LL        +  + +A V
Sbjct: 332 YFEEYFAMNYSLPKLDKIAIP-DFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATV 390

Query: 323 IIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQH 382
           + HE+ H WFGN+VT   W + WLNEGF  + +        G  +   +      +L + 
Sbjct: 391 VAHELVHQWFGNIVTMDWWEDLWLNEGFASFFE------FLGVNHAETDWQMRDQMLLED 444

Query: 383 MDITGEENPLNKLRVKIEPGVDPDD---TYNETPYEKGFCFVSYLAHLVGDQDQFDSFLK 439
           +    E++ L      I     PD+    ++   Y KG   +  L   +   + F    +
Sbjct: 445 VLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWI-KPENFQKGCQ 503

Query: 440 AYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWP 489
            Y+ +++F++    DF    LE    L  K V        D W    G+P
Sbjct: 504 MYLEKYQFKNAKTSDFW-AALEEASRLPVKEV-------MDTWTRQMGYP 545


>gi|239754599 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 294

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 42/128 (32%), Positives = 48/128 (37%), Gaps = 31/128 (24%)

Query: 18  HSAQAVDVASASNFRAFELLHLH--LDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGA 75
           HSA     A A+N  A ELL L   L  RA  GP             A L  RC+ P  A
Sbjct: 23  HSALGAQPAQAANGDADELLELSALLQPRAGRGP------------CATLSGRCITP--A 68

Query: 76  AELRLDSH----PCLEVTAAALRRERPG----SEEPPAE-------PVSFYTQPFSHYGQ 120
             L L SH     C  + A A     PG     +EPP+        P     Q  S  G 
Sbjct: 69  TALLLLSHRLRAQCRPMQATAAEAGSPGLGRLGKEPPSRESWTGSAPRRCPCQDASRAGS 128

Query: 121 ALCVSFPQ 128
            +C S PQ
Sbjct: 129 GVCRSRPQ 136


>gi|42475941 zinc finger protein 261 [Homo sapiens]
          Length = 1370

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 5/80 (6%)

Query: 46  EFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTA-AALRRERPGSEE-- 102
           E  PP PGAG+   S   +L+   L P+    L+       E T+ A  RR  PG EE  
Sbjct: 122 EVVPPDPGAGANSCSPEGLLE--PLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEEL 179

Query: 103 PPAEPVSFYTQPFSHYGQAL 122
           P  +P S    P    G+ L
Sbjct: 180 PQGQPQSPNAPPSPSVGETL 199


>gi|4827067 zinc finger protein 261 [Homo sapiens]
          Length = 1370

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 5/80 (6%)

Query: 46  EFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTA-AALRRERPGSEE-- 102
           E  PP PGAG+   S   +L+   L P+    L+       E T+ A  RR  PG EE  
Sbjct: 122 EVVPPDPGAGANSCSPEGLLE--PLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEEL 179

Query: 103 PPAEPVSFYTQPFSHYGQAL 122
           P  +P S    P    G+ L
Sbjct: 180 PQGQPQSPNAPPSPSVGETL 199


>gi|219273466 hypothetical protein LOC29125 [Homo sapiens]
          Length = 178

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 1/64 (1%)

Query: 50  PGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCL-EVTAAALRRERPGSEEPPAEPV 108
           PG G G  G  G   L L  L+  GA E  L+ HP L  +  +A+ R    S +   EP 
Sbjct: 22  PGVGCGGDGARGGGELSLSNLDLPGAGEAGLEHHPLLGHLFISAVPRWPHLSSQSGVEPP 81

Query: 109 SFYT 112
             +T
Sbjct: 82  DRWT 85


>gi|94536786 hypothetical protein LOC79091 [Homo sapiens]
          Length = 404

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 7/66 (10%)

Query: 49  PPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPV 108
           PPG G G+ G S  A  D    E    AE +LD    L+V    +RR R  S+  PA P+
Sbjct: 88  PPGSGHGNEGFSLQAGTDTTGQE---VAEAQLDEDGDLDV----VRRPRAASDSNPAGPL 140

Query: 109 SFYTQP 114
                P
Sbjct: 141 RDKVHP 146


>gi|98986321 gliomedin [Homo sapiens]
          Length = 551

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 12/84 (14%)

Query: 57  RGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFS 116
           RGLS      LR LE +   E R DS   L    A L R   G+  PP +P S      S
Sbjct: 42  RGLSSA----LRALEAQRGREQREDS--ALRSFLAELSRAPRGASAPPQDPASSARNKRS 95

Query: 117 HYGQALCVSFPQPCRAAERLQVLL 140
           H G+      P P   AE   +L+
Sbjct: 96  HSGE------PAPHIRAESHDMLM 113


>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
          Length = 1349

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 12/93 (12%)

Query: 224  QPIPSYL--IALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPY 281
            +P P Y+  +   +  ++S+   P    +  P + +   E  +        T      P 
Sbjct: 979  EPPPFYVPEVGSPLSSVMSSPPLPTEGPFGHPTIPEENGENASNSTLPLTQTPTGGRSPE 1038

Query: 282  VWGRYDLLFMPPSFPFGGMENPCLTF---VTPC 311
             WGR       P FPFGG+E P + F   + PC
Sbjct: 1039 PWGR-------PEFPFGGLETPAMMFPHQLPPC 1064


>gi|239756018 PREDICTED: similar to hCG1790963 [Homo sapiens]
          Length = 196

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 10/103 (9%)

Query: 4   GEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTA 63
           GE +P       P       +VA   N +  E        +A  GPPGP + S  L  TA
Sbjct: 7   GEGTPARQDLPAPRGYTLTENVARILNRKLLEHAVKEERRQAAHGPPGPHSDSHSLRDTA 66

Query: 64  VLDLRCLEPEGAAELRLDS-HPCLEVTAAALRRERPGSEEPPA 105
                  EP    EL   +  P LE   ++   ERP +  PP+
Sbjct: 67  -------EPGAMEELPCSALVPSLETCFSS--SERPANSRPPS 100


>gi|239750538 PREDICTED: hypothetical protein XP_002347438 [Homo
           sapiens]
          Length = 196

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 10/103 (9%)

Query: 4   GEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTA 63
           GE +P       P       +VA   N +  E        +A  GPPGP + S  L  TA
Sbjct: 7   GEGTPARQDLPAPRGYTLTENVARILNRKLLEHAVKEERRQAAHGPPGPHSDSHSLRDTA 66

Query: 64  VLDLRCLEPEGAAELRLDS-HPCLEVTAAALRRERPGSEEPPA 105
                  EP    EL   +  P LE   ++   ERP +  PP+
Sbjct: 67  -------EPGAMEELPCSALVPSLETCFSS--SERPANSRPPS 100


>gi|4507431 thyrotrophic embryonic factor isoform 1 [Homo sapiens]
          Length = 303

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 20/42 (47%), Positives = 24/42 (57%), Gaps = 1/42 (2%)

Query: 41 LDLRAEFGP-PGPGAGSRGLSGTAVLDLRCLEPEGAAELRLD 81
          +D +A  GP PG  AG RGLSG+  L L+ L      E RLD
Sbjct: 12 VDPQAGPGPGPGRAAGERGLSGSFPLVLKKLMENPPREARLD 53


>gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
           [Homo sapiens]
          Length = 311

 Score = 30.4 bits (67), Expect = 5.3
 Identities = 45/158 (28%), Positives = 58/158 (36%), Gaps = 21/158 (13%)

Query: 2   ASGEHSPG-------SGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPG--P 52
           +S  H PG       SG  RR    A  V V         E L LH D+RA    P    
Sbjct: 37  SSSVHRPGAPGLPLASGPGRRRFPQALIVGVKKGGTRALLEFLRLHPDVRALGSEPHFFD 96

Query: 53  GAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPV--SF 110
               RGL+    L  R L+     ++ ++  P   VT  A RR    S +     V  + 
Sbjct: 97  RCYERGLAWYRSLMPRTLD----GQITMEKTPSYFVTREAPRRIHAMSPDTKLIVVVRNP 152

Query: 111 YTQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGP 148
            T+  S Y Q L  +   P   A      L +R G GP
Sbjct: 153 VTRAISDYAQTLSKTPGLPSFRA------LAFRHGLGP 184


>gi|66932990 folylpolyglutamate synthase isoform b [Homo sapiens]
          Length = 537

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 19/83 (22%)

Query: 71  EPEGAAELRLDSHP------------CLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHY 118
           EP G+A L L  HP            C+      + + R    +PP+ P    T P +H 
Sbjct: 443 EPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPVAHS 502

Query: 119 GQALCVSFPQPCRAAERLQVLLT 141
           G ++        R A  + VL+T
Sbjct: 503 GASI-------LREAAAIHVLVT 518


>gi|66932984 folylpolyglutamate synthase isoform a precursor [Homo
           sapiens]
          Length = 587

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 19/83 (22%)

Query: 71  EPEGAAELRLDSHP------------CLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHY 118
           EP G+A L L  HP            C+      + + R    +PP+ P    T P +H 
Sbjct: 493 EPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPVAHS 552

Query: 119 GQALCVSFPQPCRAAERLQVLLT 141
           G ++        R A  + VL+T
Sbjct: 553 GASI-------LREAAAIHVLVT 568


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,405,224
Number of Sequences: 37866
Number of extensions: 1378596
Number of successful extensions: 3129
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3077
Number of HSP's gapped (non-prelim): 34
length of query: 650
length of database: 18,247,518
effective HSP length: 109
effective length of query: 541
effective length of database: 14,120,124
effective search space: 7638987084
effective search space used: 7638987084
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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