Guide to the Human Genome
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Name: LTA4H Sequence: fasta or formatted (611aa) NCBI GI: 4505029
Description:

leukotriene A4 hydrolase

Referenced in:

Aminopeptidases
Arachidonate, Prostaglandins, and Leukotrienes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         38           2
 C cysteine            1.8         11           1
 D aspartate           5.6         34           2
 E glutamate           6.7         41           1
 F phenylalanine       4.4         27           1
 G glycine             4.9         30           2
 H histidine           2.6         16           1
 I isoleucine          5.1         31           1
 K lysine              6.5         40           1
 L leucine            11.3         69           2
 M methionine          1.8         11           1
 N asparagine          3.4         21           2
 P proline             5.7         35           2
 Q glutamine           4.3         26           1
 R arginine            3.8         23           2
 S serine              7.4         45           2
 T threonine           6.5         40           2
 V valine              6.2         38           2
 W tryptophan          2.1         13           1
 Y tyrosine            3.6         22           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   leukotriene A4 hydrolase 
RNPEP                 0.289   arginyl aminopeptidase 
RNPEPL1               0.179   arginyl aminopeptidase (aminopeptidase B)-like 1 [Ho...
LNPEP                 0.076   leucyl/cystinyl aminopeptidase isoform 1 
LNPEP                 0.076   leucyl/cystinyl aminopeptidase isoform 2 
NPEPPS                0.074   aminopeptidase puromycin sensitive 
ANPEP                 0.061   membrane alanine aminopeptidase precursor 
LVRN                  0.061   laeverin 
ENPEP                 0.056   glutamyl aminopeptidase 
ERAP1                 0.052   type 1 tumor necrosis factor receptor shedding amino...
ERAP1                 0.052   type 1 tumor necrosis factor receptor shedding amino...
TRHDE                 0.049   thyrotropin-releasing hormone degrading enzyme 
ERAP2                 0.047   endoplasmic reticulum aminopeptidase 2 
ERAP2                 0.047   endoplasmic reticulum aminopeptidase 2 
C9orf3                0.020   aminopeptidase O 
PCDHGA5               0.006   protocadherin gamma subfamily A, 5 isoform 2 precurs...
PCDHGA5               0.006   protocadherin gamma subfamily A, 5 isoform 1 precurs...
ACTL9                 0.005   actin-like 9 
DNAH6                 0.004   dynein, axonemal, heavy polypeptide 6 
EPHA5                 0.004   ephrin receptor EphA5 isoform b precursor 
EPHA5                 0.004   ephrin receptor EphA5 isoform a precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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