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Search of human proteins with 40316837
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
(1223 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 2451 0.0
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 1731 0.0
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 1240 0.0
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 922 0.0
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 857 0.0
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 848 0.0
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 845 0.0
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 699 0.0
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 654 0.0
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 643 0.0
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 643 0.0
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 634 0.0
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 634 0.0
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 437 e-122
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 432 e-121
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 429 e-119
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 425 e-118
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 423 e-118
gi|66932949 ATPase type 13A4 [Homo sapiens] 90 1e-17
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 81 5e-15
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 81 5e-15
gi|148839292 ATPase type 13A3 [Homo sapiens] 78 6e-14
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 74 7e-13
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 74 7e-13
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 72 2e-12
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 72 2e-12
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 71 6e-12
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 71 6e-12
gi|66730421 ATPase type 13A5 [Homo sapiens] 65 5e-10
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 64 9e-10
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 2451 bits (6353), Expect = 0.0
Identities = 1223/1223 (100%), Positives = 1223/1223 (100%)
Query: 1 MDTLRAVPLFSISGLFSFPYRVSHGIAGILLGEMAVCAKKRPPEEERRARANDREYNEKF 60
MDTLRAVPLFSISGLFSFPYRVSHGIAGILLGEMAVCAKKRPPEEERRARANDREYNEKF
Sbjct: 1 MDTLRAVPLFSISGLFSFPYRVSHGIAGILLGEMAVCAKKRPPEEERRARANDREYNEKF 60
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL
Sbjct: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA
Sbjct: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
Query: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK
Sbjct: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
Query: 241 LDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRT 300
LDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRT
Sbjct: 241 LDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRT 300
Query: 301 SIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLSF 360
SIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLSF
Sbjct: 301 SIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLSF 360
Query: 361 WSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVE 420
WSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVE
Sbjct: 361 WSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVE 420
Query: 421 YIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKKFL 480
YIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKKFL
Sbjct: 421 YIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKKFL 480
Query: 481 FWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTAARNFG 540
FWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTAARNFG
Sbjct: 481 FWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTAARNFG 540
Query: 541 FVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILL 600
FVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILL
Sbjct: 541 FVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILL 600
Query: 601 DRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSRED 660
DRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSRED
Sbjct: 601 DRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSRED 660
Query: 661 RLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYS 720
RLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYS
Sbjct: 661 RLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYS 720
Query: 721 CKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLE 780
CKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLE
Sbjct: 721 CKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLE 780
Query: 781 AVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKA 840
AVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKA
Sbjct: 781 AVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKA 840
Query: 841 VTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLR 900
VTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLR
Sbjct: 841 VTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLR 900
Query: 901 MCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQD 960
MCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQD
Sbjct: 901 MCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQD 960
Query: 961 VPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQL 1020
VPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQL
Sbjct: 961 VPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQL 1020
Query: 1021 ADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMF 1080
ADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMF
Sbjct: 1021 ADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMF 1080
Query: 1081 PNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQLVRK 1140
PNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQLVRK
Sbjct: 1081 PNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQLVRK 1140
Query: 1141 KQKAQHRCMRRVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFTTRSSSSWIE 1200
KQKAQHRCMRRVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFTTRSSSSWIE
Sbjct: 1141 KQKAQHRCMRRVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFTTRSSSSWIE 1200
Query: 1201 SLRRKKSDSASSPSGGADKPLKG 1223
SLRRKKSDSASSPSGGADKPLKG
Sbjct: 1201 SLRRKKSDSASSPSGGADKPLKG 1223
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 1731 bits (4482), Expect = 0.0
Identities = 841/1191 (70%), Positives = 1005/1191 (84%), Gaps = 7/1191 (0%)
Query: 37 CAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLF 96
C++K+ E ER +ANDREYNEKFQYA N I TSKYNILTFLP+NLFEQFQ VAN YFL
Sbjct: 3 CSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLC 62
Query: 97 LLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGIL 156
LLILQLIP+ISSL+WFTTIVPLVLV+T+TAVKDATDDYFRHKSDNQVNNRQS+VLIN L
Sbjct: 63 LLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKL 122
Query: 157 QQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVT 216
Q E+WMNV VGDIIKLENNQFVAADLLLLSSSEPHGLCY+ETAELDGETN+KVR A+ VT
Sbjct: 123 QNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVT 182
Query: 217 SELG-DISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWC 275
SELG DIS+LA FDG V+CE PNNKLDKF G L WK++K L+N+ ++LRGC+LRNT WC
Sbjct: 183 SELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSWC 242
Query: 276 FGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEV 335
FG+VIFAGPDTKLMQNSG+TKFKRTSIDRLMNTLVLWIFGFL+C+G+ILAIGN+IWE +
Sbjct: 243 FGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQT 302
Query: 336 GMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKK 395
G +F+ +L W+E S+ FSGFL+FWSYIIILNTVVPISLYVSVEVIRLGHSYFINWD+K
Sbjct: 303 GDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRK 362
Query: 396 MFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG 455
M+ +K PA ARTTTLNEELGQ+EYIFSDKTGTLTQNIM F +CSING YG+V D L
Sbjct: 363 MYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLD 422
Query: 456 HKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEK 515
K E+ + EPVDFS AD++F F+D L+E++K+GDP HEF RLL+LCHTVMSEE
Sbjct: 423 QKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEEN 482
Query: 516 NEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRK 575
+ GEL Y+ QSPDEGALVTAARNFGF+F+SRTP+TIT+ E+GT +TYQLLA LDFNN RK
Sbjct: 483 SAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRK 542
Query: 576 RMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKD 635
RMSVIVRNPEG+I+LY KGADTIL ++LH S + LL+ T DHL+E+AGEGLRTL +AY+D
Sbjct: 543 RMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRD 602
Query: 636 LDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIAL 695
LD++Y++EW + A+ A + R++R+A +YEE+E ++MLLGATA+EDKLQ+GV ET+
Sbjct: 603 LDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTS 662
Query: 696 LTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMD 755
L+LANIKIWVLTGDKQETA+NIGY+C MLTDDM +VF++ G+ +EVREELRKA++ +
Sbjct: 663 LSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFG 722
Query: 756 SSRSVGNGFTYQDKLSSSKLTSVL-EAVAGEYALVINGHSLAHALEADMELEFLETACAC 814
+R+ NG +K +L S++ E + G+YAL+INGHSLAHALE+D++ + LE AC C
Sbjct: 723 QNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMC 782
Query: 815 KAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVL 874
K VICCRVTPLQKAQVVELVKKY+ AVTLAIGDGANDVSMIK+AHIGVGISGQEG+QAVL
Sbjct: 783 KTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVL 842
Query: 875 ASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVY 934
ASDYSF+QF++LQRLLLVHGRWSY RMCKFLCYFFYKNFAFT+VHFWFGFFCGFSAQTVY
Sbjct: 843 ASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVY 902
Query: 935 DQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQG 994
DQ+FITL+NIVYTSLPVLAMG+FDQDV +Q S++ P+LY+PGQLNLLFNKR+FFIC+ G
Sbjct: 903 DQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHG 962
Query: 995 IYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINH 1054
IYTS+++FFIPYG F + +DG +ADYQSFAVT+ATSLVIVVSVQI LDT YWT INH
Sbjct: 963 IYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINH 1022
Query: 1055 FFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPV 1114
FIWGS+A+YF+ILF MHSNG+F +FPNQF FVGNA+++L Q +WL I+LTTV +MPV
Sbjct: 1023 VFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPV 1082
Query: 1115 VAFRFLRLNLKPDLSDTVRYTQLVRKKQKAQHRCMRRVGRTGSRRSGYAFSHQEGFGELI 1174
VAFRFL+++L P LSD +R Q +KK + R R+ SRRSGYAF+HQEG+GELI
Sbjct: 1083 VAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRTRRSSSRRSGYAFAHQEGYGELI 1142
Query: 1175 MSGKNMRLSSLALSS---FTTRSSSSWIESLRRKKSDSASSPSGGADKPLK 1222
SGKNMR + +S T +S+SWIE+L +K +D+ SS S DK +K
Sbjct: 1143 TSGKNMRAKNPPPTSGLEKTHYNSTSWIENLCKKTTDTVSSFS--QDKTVK 1191
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 1240 bits (3209), Expect = 0.0
Identities = 637/1191 (53%), Positives = 841/1191 (70%), Gaps = 50/1191 (4%)
Query: 48 RARANDREYNE-------KF------QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYF 94
+ +ANDR+Y+E KF +YA+N IKT KYN TF+P+NLFEQF+ AN YF
Sbjct: 65 QVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYF 124
Query: 95 LFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLING 154
L LLILQ +PQIS+L+W+TT+VPL++VL +TA+KD DD RHK D ++NNR +V+ +G
Sbjct: 125 LALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDG 184
Query: 155 ILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIP 214
+ +W + VGD+I+L+ N FV AD+LLLSSSEP+ LCY+ETAELDGETN+K + ++
Sbjct: 185 RFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLE 244
Query: 215 VTSE-LGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE 273
+T + L LA FDG + CE PNN+LDKF+GTL+W+ FPL +LLRGCV+RNT+
Sbjct: 245 ITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVIRNTD 304
Query: 274 WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH 333
+C GLVIFAG DTK+M+NSG+T+FKRT ID LMN +V IF L+ + LAIG+A WE
Sbjct: 305 FCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEA 364
Query: 334 EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWD 393
+VG YL +D D+ + GFL FW YII+LNT+VPISLYVSVEVIRLG S+FINWD
Sbjct: 365 QVG-NSSWYL-YDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWD 422
Query: 394 KKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDV 453
+M+ +K TPA+ARTTTLNE+LGQ+ YIFSDKTGTLTQNIM F KC ING YGD D
Sbjct: 423 LQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDA 482
Query: 454 LGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKIG-DPHTHEFFRLLSLCHTVMS 512
H + E VDFS+N AD K F+D L+E ++ G +P +FF LL++CHTVM
Sbjct: 483 SQHN---HNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVM- 538
Query: 513 EEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNN 572
++ +G+L Y+A SPDEGALV AARNFGF F +RT TIT+ E+GT TY +LAILDFN+
Sbjct: 539 VDRTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNS 598
Query: 573 IRKRMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLA 632
RKRMS+IVR PEG I+LYCKGADT++ +RLH T D L+ +A E LRTL L
Sbjct: 599 DRKRMSIIVRTPEGNIKLYCKGADTVIYERLHR-MNPTKQETQDALDIFANETLRTLCLC 657
Query: 633 YKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPET 692
YK+++E+ + EW ++ + AS+A +R++ L +YEE+E +++LLGATAIEDKLQ GVPET
Sbjct: 658 YKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPET 717
Query: 693 IALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAR-- 750
I+ L A+IKIWVLTGDK+ETA NIG++C++LT+D T + +++L R E ++ R
Sbjct: 718 ISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGG 777
Query: 751 ------------------EKMMDSSRSVGNGFTYQDKLSSSKLTSV-LEAVAGEYALVIN 791
+ + + S N + K +K+ + E +
Sbjct: 778 VYAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQ 837
Query: 792 GHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGAND 851
A + + F++ AC C AVICCRVTP QKA VV+LVK+YKKA+TLAIGDGAND
Sbjct: 838 SKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGAND 897
Query: 852 VSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYK 911
V+MIKTAHIGVGISGQEG+QAV++SDYSF+QF++LQRLLLVHGRWSY+RMCKFL YFFYK
Sbjct: 898 VNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYK 957
Query: 912 NFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPK 971
NFAFT+VHFW+ FF G+SAQT Y+ +FITLYN++YTSLPVL MG+ DQDV ++ S+ +P
Sbjct: 958 NFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPG 1017
Query: 972 LYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVA 1031
LY GQ +LLFN + FF+ + G+ TS+++FFIP G + DG +DYQSFAVT+A
Sbjct: 1018 LYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIA 1077
Query: 1032 TSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQ 1091
++LVI V+ QIGLDT YWT +N F I+GS+A+YF I+F HS G+ +FP+ F+F G A
Sbjct: 1078 SALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTAS 1137
Query: 1092 NTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQLVRKKQKAQHRCMRR 1151
N L QP +WLTI+LT VC++PVVA RFL + + P SD + Q RK+ KA+ + RR
Sbjct: 1138 NALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKI---QKHRKRLKAEEQWQRR 1194
Query: 1152 --VGRTG--SRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFTTRSSSSW 1198
V R G +RRS YAFSHQ G+ +LI SG+++R L + ++ +
Sbjct: 1195 QQVFRRGVSTRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIVADGTAEY 1245
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 922 bits (2382), Expect = 0.0
Identities = 529/1229 (43%), Positives = 744/1229 (60%), Gaps = 103/1229 (8%)
Query: 48 RARANDREYNEKFQ-----------YASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLF 96
+ +AN+R YN +F+ Y +N I+T+KYN +FLP+NL+EQF V+N +FL
Sbjct: 108 KVQANNRAYNGQFKEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLI 167
Query: 97 LLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGIL 156
++ILQ IP IS+L WF+ P+V +L I A +D DD RHKSD +NNR Q+L+
Sbjct: 168 IIILQSIPDISTLPWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSF 227
Query: 157 QQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVT 216
+Q++W ++CVGD++ L + V AD+LLL+S+EP LCY+ET ++DGETN+K RQA+ VT
Sbjct: 228 KQKKWQDLCVGDVVCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVT 287
Query: 217 -SELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWC 275
EL I K+A F G V CE PN+++ F G L W + K+ L N+LLRGC +RNT+ C
Sbjct: 288 HKELATIKKMASFQGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRNTDTC 347
Query: 276 FGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEV 335
+GLVI+AG DTK+M+N G+ KRT +D LMN LV+ IF +V + ++LA G E
Sbjct: 348 YGLVIYAGFDTKIMKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKE- 406
Query: 336 GMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKK 395
+ Y S F FWS++I+L+ +P+S+++ E I LG+S FI+WD +
Sbjct: 407 -FKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQ 465
Query: 396 MFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG 455
M+ + PA+AR+T+LN+ LGQVEYIFSDKTGTLTQNI+ FNKC I+G YG
Sbjct: 466 MYYKPQDVPAKARSTSLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGP------ 519
Query: 456 HKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKI-GDPHTHEFFRLLSLCHTVM--- 511
+E RP+ + +N AD K LF + +LL V+ GD EF+RLL++CHTVM
Sbjct: 520 -DSEATTRPKENPYLWNKFADGKLLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRE 578
Query: 512 SEEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFN 571
S + +L Y+A SPDEGALVTAARNFG+VF SRT T+T+ E+G YQ+LAI+DFN
Sbjct: 579 SPRERPDQLLYQAASPDEGALVTAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIMDFN 638
Query: 572 NIRKRMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVL 631
+ RKRMSV+VR PEG I LY KGADT++ +RLH + T + L +A E LRTL L
Sbjct: 639 STRKRMSVLVRKPEGAICLYTKGADTVIFERLHR-RGAMEFATEEALAAFAQETLRTLCL 697
Query: 632 AYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPE 691
AY+++ E+ YE+W +R +ASL +R L LLGATAIED+LQ GVPE
Sbjct: 698 AYREVAEDIYEDWQQRHQEASLLLQNRAQAL----------QQLLGATAIEDRLQDGVPE 747
Query: 692 TIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDM-----------TEVFIVTGHTVL 740
TI L +NIKIWVLTGDKQETAVNIG++C++L+++M E + + +L
Sbjct: 748 TIKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENSNNLL 807
Query: 741 EVREELRKAR----------EKMMDSSRSVGN---------------GFTYQDKLSSSKL 775
RE L + + +K++ S R G + +D L + +L
Sbjct: 808 -TRESLSQVKLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRL 866
Query: 776 TSVLEAVAGEYALVINGHSLA-HALEADMELEFLETACACKAVICCRVTPLQKAQVVELV 834
+ + A S A + E E F++ A C+AVICCRVTP QKA +V LV
Sbjct: 867 SLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALV 926
Query: 835 KKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHG 894
KKY + VTLAIGDGAND++MIKTA +GVG++GQEG+QAV SD+ QF FLQRLLLVHG
Sbjct: 927 KKYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHG 986
Query: 895 RWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAM 954
RWSY+R+CKFL YFFYK+ A MV WF + GF+ Q +Y+ +F+ L+N++Y++LPVL +
Sbjct: 987 RWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYI 1046
Query: 955 GVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATR 1014
G+F+QDV ++S+E P+LY GQ + LFN F IA G+ TS++ FF+ + D
Sbjct: 1047 GLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISRDTA- 1105
Query: 1015 DDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSN 1074
+D+QSFAV VA S ++ +++++ L YWTA+ I SL Y + S
Sbjct: 1106 -GPASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSF 1164
Query: 1075 GLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRY 1134
LF + P F F+ + ++ P++ L ++L+ + PV+A R + LK
Sbjct: 1165 WLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLALRVIFPALK--------- 1215
Query: 1135 TQLVRKKQKAQHRCMRRV----------GRTGSRRSGYAFSHQEGFGELIMSGKNMRLSS 1184
+L K++K + + + +RRS YAFSH+EG+ LI G +R
Sbjct: 1216 -ELRAKEEKVEEGPSEEIFTMEPLPHVHRESRARRSSYAFSHREGYANLITQGTILRRGP 1274
Query: 1185 LALSSFTTRSSSSWIESLRRKKSDSASSP 1213
S + ESL ++ASSP
Sbjct: 1275 GVSSDIAS-------ESLDPSDEEAASSP 1296
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 857 bits (2214), Expect = 0.0
Identities = 455/1085 (41%), Positives = 669/1085 (61%), Gaps = 59/1085 (5%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
++ +N + T+KYNI+TFLP L+ QF+ AN++FLF+ +LQ IP +S +TT+VPL+
Sbjct: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
+L + A+K+ +D RHK+DN VN +Q+QVL NG + W V VG+I+K+ N + + A
Sbjct: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPA 167
Query: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
DL+ LSSSEP +CYIET+ LDGETN+K+RQ +P TS++ D+ L + G + CE PN
Sbjct: 168 DLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227
Query: 241 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 299
L F G + PL +LLRG LRNT+W G+V++ G DTKLMQNS K
Sbjct: 228 LYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKL 287
Query: 300 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGF-L 358
++++R+ N +L +F L+ M ++ ++G+AIW + W ++ S F L
Sbjct: 288 SNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-----DWYLNLNYGGASNFGL 342
Query: 359 SFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQ 418
+F ++II+ N ++PISL V++EV++ +YFINWD M T A ART+ LNEELGQ
Sbjct: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
Query: 419 VEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNP----- 473
V+YIFSDKTGTLT N+M F KC+I G +YG V PEP D+ +P
Sbjct: 403 VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHV-------------PEPEDYGCSPDEWQN 449
Query: 474 --LADKKFLFWDPSLLEAVKIGDPHTH---EFFRLLSLCHTVMSEEKNEGELYYKAQSPD 528
D+K F D SLLE ++ P EF ++++CHT + E + + ++ Y+A SPD
Sbjct: 450 SQFGDEK-TFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGD-KIIYQAASPD 507
Query: 529 EGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKI 588
EGALV AA+ FVF RTP ++ + +G Y+LL +L+F + RKRMSVIVR P GK+
Sbjct: 508 EGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKL 567
Query: 589 RLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERR 648
RLYCKGADT++ DRL T + T+ HL ++A EGLRTL A ++ E ++EW
Sbjct: 568 RLYCKGADTVIYDRLAE-TSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVY 626
Query: 649 LQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTG 708
+AS + +R +L YE +E N+ LLGATAIEDKLQ VPETI L A+IKIW+LTG
Sbjct: 627 QRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTG 686
Query: 709 DKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQD 768
DKQETA+NIG+SCK+L +M + I G L RE + ++G+ ++
Sbjct: 687 DKQETAINIGHSCKLLKKNMGMIVINEG--------SLDGTRETLSRHCTTLGDALRKEN 738
Query: 769 KLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKA 828
++AL+I+G +L +AL + FL+ A +CKAVICCRV+PLQK+
Sbjct: 739 ----------------DFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKS 782
Query: 829 QVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQR 888
+VVE+VKK K VTLAIGDGANDVSMI+TAH+GVGISG EG+QA +SDYS +QFK+L+
Sbjct: 783 EVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKN 842
Query: 889 LLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTS 948
LL++HG W+Y R+ K + Y FYKN ++ WF F GFS Q +++++ I LYN+++T+
Sbjct: 843 LLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTA 902
Query: 949 LPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGV 1008
+P L +G+F++ ++ ++YP+LY+ Q L FN + F++ G++ SV++F+ P
Sbjct: 903 MPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKA 962
Query: 1009 FADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAIL 1068
T + +DY V T +VI V ++ GL+T YWT +H IWGS+A++ +
Sbjct: 963 LQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALW-VVF 1021
Query: 1069 FAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDL 1128
F ++S+ L+ P G A + W+ ++ V ++ V ++ ++ L
Sbjct: 1022 FGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL 1080
Query: 1129 SDTVR 1133
D V+
Sbjct: 1081 VDEVQ 1085
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 848 bits (2191), Expect = 0.0
Identities = 466/1138 (40%), Positives = 677/1138 (59%), Gaps = 69/1138 (6%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
++ N I T+KY++LTFLP L+EQ + AN +FLF+ +LQ IP +S +TT+VPL++
Sbjct: 67 KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLII 126
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
+LTI +K+ +D+ RHK+DN VN +++ VL NG+ W V VGDI+K+ N Q++ A
Sbjct: 127 ILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPA 186
Query: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
D++LLSSSEP +CY+ETA LDGETN+K+RQ + T+++ L K G + CE PN
Sbjct: 187 DVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRH 246
Query: 241 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 299
L F+G L ++ L +LLRG LRNT+W FG+V++ G DTKLMQNS + KR
Sbjct: 247 LYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKR 306
Query: 300 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLS 359
++++++ N +L +FG L+ M ++ + G W G + D D+ ++
Sbjct: 307 SNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYN---- 362
Query: 360 FWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQV 419
++II+ N ++PISL V++EV++ + FINWD M+ + TPA ART+ LNEELGQV
Sbjct: 363 LLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQV 422
Query: 420 EYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFS-FNPLADKK 478
+Y+FSDKTGTLT NIM F KCSI G +YG H EL P DF P
Sbjct: 423 KYLFSDKTGTLTCNIMNFKKCSIAGVTYG-------HFPELAREPSSDDFCRMPPPCSDS 475
Query: 479 FLFWDPSLLEAVKIGDPHT---HEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTA 535
F DP LL+ ++ P EF LL++CHTV+ E K+ + Y+A SPDE ALV
Sbjct: 476 CDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPE-KDGDNIIYQASSPDEAALVKG 534
Query: 536 ARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGA 595
A+ GFVF +RTP ++ + MG T+ +L +L+F++ RKRMSVIVR P G++RLYCKGA
Sbjct: 535 AKKLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGA 594
Query: 596 DTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQ 655
D ++ +RL ++ + T+ HL +A EGLRTL +AY DL E YEEW + +AS
Sbjct: 595 DNVIFERLSKDSK-YMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTIL 653
Query: 656 DSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAV 715
R RL YE +E N++LLGATAIED+LQ GVPETIA L A IKIWVLTGDKQETA+
Sbjct: 654 KDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAI 713
Query: 716 NIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKL 775
NIGYSC++++ +M +L + L R + +GN
Sbjct: 714 NIGYSCRLVSQNMA--------LILLKEDSLDATRAAITQHCTDLGN------------- 752
Query: 776 TSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVK 835
L + AL+I+GH+L +AL ++ FL+ A +CKAVICCRV+PLQK+++V++VK
Sbjct: 753 ---LLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVK 809
Query: 836 KYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGR 895
K KA+TLAIGDGANDV MI+TAH+GVGISG EG+QA SDY+ +QF +L++LLLVHG
Sbjct: 810 KRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGA 869
Query: 896 WSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMG 955
WSY R+ K + Y FYKN ++ WF F GFS Q +++++ I LYN+++T+LP +G
Sbjct: 870 WSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLG 929
Query: 956 VFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRD 1015
+F++ ++ + +P+LY+ Q FN + F+ + S+++F+ P T
Sbjct: 930 IFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFPMKALEHDTVL 989
Query: 1016 DGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNG 1075
DY V T +V+ V ++ GL+T WT +H +WGS+ + + F ++S
Sbjct: 990 TSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLTWL-VFFGIYST- 1047
Query: 1076 LFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYT 1135
++ P G A L+ WL + L C++ VA+R + K L + V+
Sbjct: 1048 IWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHTCKKTLLEEVQEL 1107
Query: 1136 QLVR-------------KKQKAQHRCMRRVGR----TGSRRS--------GYAFSHQE 1168
+ K+ + R ++R+GR T R S GYAFS +E
Sbjct: 1108 ETKSRVLGKAVLRDSNGKRLNERDRLIKRLGRKTPPTLFRGSSLQQGVPHGYAFSQEE 1165
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 845 bits (2183), Expect = 0.0
Identities = 447/1078 (41%), Positives = 662/1078 (61%), Gaps = 60/1078 (5%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
++ +N + T+KYNI+TFLP L+ QF+ AN++FLF+ +LQ IP +S +TT+VPL+
Sbjct: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
+L + A+K+ +D RHK+DN VN +Q+QVL NG + W V VGDI+ ++ +++ A
Sbjct: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPA 167
Query: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
D +LLSSSEP +CYIET+ LDGETN+K+RQ +P TS++ D+ L + G + CE PN
Sbjct: 168 DTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227
Query: 241 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 299
L F G + PL +LLRG LRNT+W G+V++ G DTKLMQNS K
Sbjct: 228 LYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKL 287
Query: 300 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGF-L 358
++++R+ N +L +F L+ M ++ ++G+AIW + W ++ S F L
Sbjct: 288 SNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-----DWYLNLNYGGASNFGL 342
Query: 359 SFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQ 418
+F ++II+ N ++PISL V++EV++ +YFINWD M T A ART+ LNEELGQ
Sbjct: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
Query: 419 VEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKK 478
V+YIFSDKTGTLT N+M F KC+I G +YG ++ G+
Sbjct: 403 VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQ-------NSQFGDEKT------------- 442
Query: 479 FLFWDPSLLEAVKIGDPHTH---EFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTA 535
F D SLLE ++ P EF ++++CHT + E + + ++ Y+A SPDEGALV A
Sbjct: 443 --FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGD-KIIYQAASPDEGALVRA 499
Query: 536 ARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGA 595
A+ FVF RTP ++ + +G Y+LL +L+F + RKRMSVIVR P GK+RLYCKGA
Sbjct: 500 AKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGA 559
Query: 596 DTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQ 655
DT++ DRL T + T+ HL ++A EGLRTL A ++ E ++EW +AS +
Sbjct: 560 DTVIYDRLAE-TSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSV 618
Query: 656 DSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAV 715
+R +L YE +E N+ LLGATAIEDKLQ VPETI L A+IKIW+LTGDKQETA+
Sbjct: 619 QNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAI 678
Query: 716 NIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKL 775
NIG+SCK+L +M + I G L RE + ++G+ ++
Sbjct: 679 NIGHSCKLLKKNMGMIVINEG--------SLDGTRETLSRHCTTLGDALRKEN------- 723
Query: 776 TSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVK 835
++AL+I+G +L +AL + FL+ A +CKAVICCRV+PLQK++VVE+VK
Sbjct: 724 ---------DFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVK 774
Query: 836 KYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGR 895
K K VTLAIGDGANDVSMI+TAH+GVGISG EG+QA +SDYS +QFK+L+ LL++HG
Sbjct: 775 KQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGA 834
Query: 896 WSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMG 955
W+Y R+ K + Y FYKN ++ WF F GFS Q +++++ I LYN+++T++P L +G
Sbjct: 835 WNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLG 894
Query: 956 VFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRD 1015
+F++ ++ ++YP+LY+ Q L FN + F++ G++ SV++F+ P T
Sbjct: 895 IFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAF 954
Query: 1016 DGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNG 1075
+ +DY V T +VI V ++ GL+T YWT +H IWGS+A++ + F ++S+
Sbjct: 955 GNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALW-VVFFGIYSS- 1012
Query: 1076 LFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVR 1133
L+ P G A + W+ ++ V ++ V ++ ++ L D V+
Sbjct: 1013 LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQ 1070
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 699 bits (1804), Expect = 0.0
Identities = 357/411 (86%), Positives = 363/411 (88%), Gaps = 26/411 (6%)
Query: 34 MAVCAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTY 93
MAVCAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTY
Sbjct: 1 MAVCAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTY 60
Query: 94 FLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLIN 153
FLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLIN
Sbjct: 61 FLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLIN 120
Query: 154 GILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAI 213
GILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAI
Sbjct: 121 GILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAI 180
Query: 214 PVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE 273
PVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE
Sbjct: 181 PVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE 240
Query: 274 WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH 333
WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH
Sbjct: 241 WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH 300
Query: 334 EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVS-VEVIRLGHSYFINW 392
EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYV V + G S
Sbjct: 301 EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVRYVPSLTWGLS----- 355
Query: 393 DKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSIN 443
E G +E FS K +L N + C++N
Sbjct: 356 --------------------RESGGPIELFFSMKMKSLRSNEKSSSSCTVN 386
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 654 bits (1687), Expect = 0.0
Identities = 399/1115 (35%), Positives = 608/1115 (54%), Gaps = 82/1115 (7%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
++ N I +SKY + F+P NLFEQF+ VAN YFL + ++QL+ + S T+ +PL
Sbjct: 38 KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPT-SPVTSGLPLFF 96
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
V+T+TA+K +D+ RH SDN+VN V+ +G L + + N+ VGDI+++ ++ A
Sbjct: 97 VITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPA 156
Query: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
DL+LLSS G C++ TA LDGETN+K A+P T+ L ++ L + C+ P
Sbjct: 157 DLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEAD 216
Query: 241 LDKFSG----TLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTK 296
L +F G T +E PL +++LLRG L+NT+ FG+ ++ G +TK+ N
Sbjct: 217 LYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKS 276
Query: 297 FKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAV------- 349
KR+++++ MNT ++ L+ VI I W+ E WDE
Sbjct: 277 QKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEE--------KWDEPWYNQKTEH 328
Query: 350 --DSAFFSGFLS-FWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAE 406
+S+ F+S F +++++ N ++PISLYV+VE+ + S+FI WD ++ + A+
Sbjct: 329 QRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQ 388
Query: 407 ARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEP 466
T+ LNEELGQVEY+F+DKTGTLT+N M F +CSING Y ++ G G P+
Sbjct: 389 VNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEIN---GRLVPEGPTPDS 445
Query: 467 VDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHE---------FFRLLSLCHTVMSEEKNE 517
+ + + L+ L L + +E FF+ +SLCHTV
Sbjct: 446 SEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQT 505
Query: 518 --------------GELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQ 563
+L Y A SPDE ALV AA G VF + +T+ V +G Y+
Sbjct: 506 DCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYK 565
Query: 564 LLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAG 623
LL IL+F++ R+RMSVIV+ P G+ L+ KGA++ +L + E T H++E+A
Sbjct: 566 LLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIE---KTRIHVDEFAL 622
Query: 624 EGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIED 683
+GLRTL +AY+ + YEE +R +A A RE++LA++++ +E +++LLGATA+ED
Sbjct: 623 KGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVED 682
Query: 684 KLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVR 743
+LQ V ETI L +A IK+WVLTGDK ETAV++ SC M + ++ + E
Sbjct: 683 RLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECA 742
Query: 744 EELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADM 803
E+LR+ + + E ++ LV++G SL+ AL
Sbjct: 743 EQLRQLARR-------------------------ITEDHVIQHGLVVDGTSLSLALREHE 777
Query: 804 ELEFLETACACKAVICCRVTPLQKAQVVELVK-KYKKAVTLAIGDGANDVSMIKTAHIGV 862
+L F+E C AV+CCR+ PLQKA+V+ L+K +K +TLA+GDGANDVSMI+ AH+G+
Sbjct: 778 KL-FMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGI 836
Query: 863 GISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWF 922
GI G+EG QA SDY+ ++FKFL +LL VHG + Y+R+ + YFFYKN F F +
Sbjct: 837 GIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLY 896
Query: 923 GFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLF 982
F+C FS QT+YD ++TLYNI +TSLP+L + +Q V P LY N L
Sbjct: 897 QFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLL 956
Query: 983 NKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGT-QLADYQSFAVTVATSLVIVVSVQ 1041
+ + F G + + FF Y + T G Q+ +F V T +VI V+V+
Sbjct: 957 SIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVK 1016
Query: 1042 IGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWL 1101
+ L+T +WT INH WGS+ YF +F++ G+ F L+ + W
Sbjct: 1017 MALETHFWTWINHLVTWGSIIFYF--VFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWF 1074
Query: 1102 TIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQ 1136
I+L V C+ + + +L P ++ + T+
Sbjct: 1075 AIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQLTE 1109
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 643 bits (1659), Expect = 0.0
Identities = 400/1106 (36%), Positives = 597/1106 (53%), Gaps = 73/1106 (6%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
+Y N I +SKY F+P NLFEQF+ VAN YFL + ++QLI + S T+ +PL
Sbjct: 44 RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPT-SPVTSGLPLFF 102
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
V+T+TA+K +D+ RHK+DN +N + +G L ++Q + VGDI+ ++ ++
Sbjct: 103 VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162
Query: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
DL+ LSS+ G C++ TA LDGE++ K A+ T + + CE P
Sbjct: 163 DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPD 222
Query: 241 LDKFSGTL--YWKENK---FPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 295
L KF G + Y N PL ++N+LLRG L+NTE FG+ I+ G +TK+ N
Sbjct: 223 LYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSK 282
Query: 296 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 349
KR+++++ MN ++ L+ +I + +W+ E R + PW E
Sbjct: 283 SQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEP-FRDE---PWYNQKTESERQ 338
Query: 350 DSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEART 409
+ F F F +++++ N ++P+S+YV+VE+ + SYFI WD+ MF + T
Sbjct: 339 RNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNT 398
Query: 410 TTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDF 469
+ LNEELGQVEYIF+DKTGTLT+N M F +C I GH Y G + +D
Sbjct: 399 SDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDS 458
Query: 470 SFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGE---------- 519
S PS+ G FFR L LCHTV ++ + +
Sbjct: 459 S-------------PSVN-----GREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGK 500
Query: 520 -LYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAIT-YQLLAILDFNNIRKRM 577
Y + SPDE ALV + GF + + + I ++LL IL F+++R+RM
Sbjct: 501 SCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEILSFDSVRRRM 560
Query: 578 SVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLD 637
SVIV++ G+I L+CKGAD+ + R+ + + ++ A EGLRTL +AYK L
Sbjct: 561 SVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVER---NAVEGLRTLCVAYKRLI 617
Query: 638 EEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLT 697
+E YE + A +A RE +LA YE++E ++ LLGATA+ED+LQ+ +TI L
Sbjct: 618 QEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQ 677
Query: 698 LANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSS 757
A IK+WVLTGDK ETA Y+CK+ + + + T R E + + + + S
Sbjct: 678 KAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTK------RIEEQSLHDVLFELS 731
Query: 758 RSV--GNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALE-------ADMELEFL 808
++V +G +D LS L A +Y L+I+G +L+ ++ + FL
Sbjct: 732 KTVLRHSGSLTRDNLSG------LSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFL 785
Query: 809 ETACACKAVICCRVTPLQKAQVVELVKKYKK-AVTLAIGDGANDVSMIKTAHIGVGISGQ 867
E +C AV+CCR+ PLQKAQ+V+L+K K+ +TLAIGDGANDVSMI AH+G+G+ G+
Sbjct: 786 EICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGK 845
Query: 868 EGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCG 927
EG QA SDY+ +FK L+++LLVHG + Y+R+ + + YFFYKN F F + FFCG
Sbjct: 846 EGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCG 905
Query: 928 FSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREF 987
FS QT+YD ++TLYNI +TSLP+L + +Q V P LY N L R F
Sbjct: 906 FSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVF 965
Query: 988 FICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTG 1047
G++ +++ FF Y VF + T Q+ +F V T +V V++++ LDT
Sbjct: 966 IYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTH 1025
Query: 1048 YWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTT 1107
YWT INHF IWGSL Y ++F++ G+ F N R L+ WL IVL
Sbjct: 1026 YWTWINHFVIWGSLLFY--VVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLV 1083
Query: 1108 VVCIMPVVAFRFLRLNLKPDLSDTVR 1133
+ ++P V + L L P ++ V+
Sbjct: 1084 TISLLPDVLKKVLCRQLWPTATERVQ 1109
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 643 bits (1659), Expect = 0.0
Identities = 400/1106 (36%), Positives = 597/1106 (53%), Gaps = 73/1106 (6%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
+Y N I +SKY F+P NLFEQF+ VAN YFL + ++QLI + S T+ +PL
Sbjct: 44 RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPT-SPVTSGLPLFF 102
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
V+T+TA+K +D+ RHK+DN +N + +G L ++Q + VGDI+ ++ ++
Sbjct: 103 VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162
Query: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
DL+ LSS+ G C++ TA LDGE++ K A+ T + + CE P
Sbjct: 163 DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPD 222
Query: 241 LDKFSGTL--YWKENK---FPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 295
L KF G + Y N PL ++N+LLRG L+NTE FG+ I+ G +TK+ N
Sbjct: 223 LYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSK 282
Query: 296 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 349
KR+++++ MN ++ L+ +I + +W+ E R + PW E
Sbjct: 283 SQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEP-FRDE---PWYNQKTESERQ 338
Query: 350 DSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEART 409
+ F F F +++++ N ++P+S+YV+VE+ + SYFI WD+ MF + T
Sbjct: 339 RNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNT 398
Query: 410 TTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDF 469
+ LNEELGQVEYIF+DKTGTLT+N M F +C I GH Y G + +D
Sbjct: 399 SDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDS 458
Query: 470 SFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGE---------- 519
S PS+ G FFR L LCHTV ++ + +
Sbjct: 459 S-------------PSVN-----GREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGK 500
Query: 520 -LYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAIT-YQLLAILDFNNIRKRM 577
Y + SPDE ALV + GF + + + I ++LL IL F+++R+RM
Sbjct: 501 SCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEILSFDSVRRRM 560
Query: 578 SVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLD 637
SVIV++ G+I L+CKGAD+ + R+ + + ++ A EGLRTL +AYK L
Sbjct: 561 SVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVER---NAVEGLRTLCVAYKRLI 617
Query: 638 EEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLT 697
+E YE + A +A RE +LA YE++E ++ LLGATA+ED+LQ+ +TI L
Sbjct: 618 QEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQ 677
Query: 698 LANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSS 757
A IK+WVLTGDK ETA Y+CK+ + + + T R E + + + + S
Sbjct: 678 KAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTK------RIEEQSLHDVLFELS 731
Query: 758 RSV--GNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALE-------ADMELEFL 808
++V +G +D LS L A +Y L+I+G +L+ ++ + FL
Sbjct: 732 KTVLRHSGSLTRDNLSG------LSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFL 785
Query: 809 ETACACKAVICCRVTPLQKAQVVELVKKYKK-AVTLAIGDGANDVSMIKTAHIGVGISGQ 867
E +C AV+CCR+ PLQKAQ+V+L+K K+ +TLAIGDGANDVSMI AH+G+G+ G+
Sbjct: 786 EICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGK 845
Query: 868 EGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCG 927
EG QA SDY+ +FK L+++LLVHG + Y+R+ + + YFFYKN F F + FFCG
Sbjct: 846 EGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCG 905
Query: 928 FSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREF 987
FS QT+YD ++TLYNI +TSLP+L + +Q V P LY N L R F
Sbjct: 906 FSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVF 965
Query: 988 FICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTG 1047
G++ +++ FF Y VF + T Q+ +F V T +V V++++ LDT
Sbjct: 966 IYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTH 1025
Query: 1048 YWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTT 1107
YWT INHF IWGSL Y ++F++ G+ F N R L+ WL IVL
Sbjct: 1026 YWTWINHFVIWGSLLFY--VVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLV 1083
Query: 1108 VVCIMPVVAFRFLRLNLKPDLSDTVR 1133
+ ++P V + L L P ++ V+
Sbjct: 1084 TISLLPDVLKKVLCRQLWPTATERVQ 1109
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 634 bits (1634), Expect = 0.0
Identities = 372/1088 (34%), Positives = 581/1088 (53%), Gaps = 65/1088 (5%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
++ N I +SKY + FLP NLFEQF+ +AN YFL + ++Q+ + S T+ +PL
Sbjct: 42 RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPT-SPVTSGLPLFF 100
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
V+T+TA+K +D+ RH++DN+VN ++ N +++ + VGD+++++ ++
Sbjct: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160
Query: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
DL+LLSS G CY+ TA LDGE+N K A+ T L + + CE P
Sbjct: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPD 220
Query: 241 LDKFSGTLYWKENKFP-----LSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 295
L KF G + N L +N+LL+G L+NTE +G+ ++ G +TK+ N
Sbjct: 221 LYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGK 280
Query: 296 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 349
KR+++++ +N ++ L+ + +W+ PW E
Sbjct: 281 SQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDE----PWYNQKTQKERE 336
Query: 350 DSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEART 409
F F S++++ N ++P+S+YV+VE+ + S+FI+WDK + + A T
Sbjct: 337 TLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNT 396
Query: 410 TTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDF 469
+ LNEELGQV+Y+F+DKTGTLT+N M F +C I+GH Y V + ++
Sbjct: 397 SDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQ---------- 446
Query: 470 SFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKN-------EGELYY 522
D ++D K+ F R L LCHTV + + EL Y
Sbjct: 447 -----TDGTLTYFD-------KVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTY 494
Query: 523 KAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAIT-YQLLAILDFNNIRKRMSVIV 581
+ SPDE ALV A+ +GF F + V I Y+LL L+F+ +R+RMSVIV
Sbjct: 495 ISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIV 554
Query: 582 RNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYY 641
+ EG I L+CKGAD+ + R+ + EL T H+ A +G RTL +A+K++ + Y
Sbjct: 555 KTQEGDILLFCKGADSAVFPRVQNHEIEL---TKVHVERNAMDGYRTLCVAFKEIAPDDY 611
Query: 642 EEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANI 701
E + ++A +A RE+++ +++++E NM L+GATA+EDKLQ ETI L A +
Sbjct: 612 ERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGL 671
Query: 702 KIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVG 761
K+WVLTGDK ETA + Y+C++ + TE+ +T T+ E + + E +++ + +
Sbjct: 672 KVWVLTGDKMETAKSTCYACRLFQTN-TELLELTTKTIEESERKEDRLHELLIEYRKKLL 730
Query: 762 NGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELE-------FLETACAC 814
+ F + T EY L+I+G +L+ L + + FL+ C
Sbjct: 731 HEFPKSTRSFKKAWTE-----HQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKC 785
Query: 815 KAVICCRVTPLQKAQVVELVKKYKKA-VTLAIGDGANDVSMIKTAHIGVGISGQEGIQAV 873
AV+CCR+ PLQKAQ+V +VK K + +TL+IGDGANDVSMI +H+G+GI G+EG QA
Sbjct: 786 TAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAA 845
Query: 874 LASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTV 933
SDYS +FK L++LLL HG Y+R+ + YFFYKN F + F + FFCGFS Q +
Sbjct: 846 RNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPL 905
Query: 934 YDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQ 993
YD ++T+YNI +TSLP+LA + +Q + P+LY N + F
Sbjct: 906 YDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFL 965
Query: 994 GIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAIN 1053
+ + FF Y +F A+ ++ ++ +F V T LV V++++ LDT +WT IN
Sbjct: 966 AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWTWIN 1025
Query: 1054 HFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMP 1113
HF IWGSLA Y + F+ G+ F Q R L+ + WL I+L + + P
Sbjct: 1026 HFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFISLFP 1083
Query: 1114 VVAFRFLR 1121
+ L+
Sbjct: 1084 EILLIVLK 1091
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 634 bits (1634), Expect = 0.0
Identities = 372/1088 (34%), Positives = 581/1088 (53%), Gaps = 65/1088 (5%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
++ N I +SKY + FLP NLFEQF+ +AN YFL + ++Q+ + S T+ +PL
Sbjct: 42 RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPT-SPVTSGLPLFF 100
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
V+T+TA+K +D+ RH++DN+VN ++ N +++ + VGD+++++ ++
Sbjct: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160
Query: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
DL+LLSS G CY+ TA LDGE+N K A+ T L + + CE P
Sbjct: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPD 220
Query: 241 LDKFSGTLYWKENKFP-----LSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 295
L KF G + N L +N+LL+G L+NTE +G+ ++ G +TK+ N
Sbjct: 221 LYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGK 280
Query: 296 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 349
KR+++++ +N ++ L+ + +W+ PW E
Sbjct: 281 SQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDE----PWYNQKTQKERE 336
Query: 350 DSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEART 409
F F S++++ N ++P+S+YV+VE+ + S+FI+WDK + + A T
Sbjct: 337 TLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNT 396
Query: 410 TTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDF 469
+ LNEELGQV+Y+F+DKTGTLT+N M F +C I+GH Y V + ++
Sbjct: 397 SDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQ---------- 446
Query: 470 SFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKN-------EGELYY 522
D ++D K+ F R L LCHTV + + EL Y
Sbjct: 447 -----TDGTLTYFD-------KVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTY 494
Query: 523 KAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAIT-YQLLAILDFNNIRKRMSVIV 581
+ SPDE ALV A+ +GF F + V I Y+LL L+F+ +R+RMSVIV
Sbjct: 495 ISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIV 554
Query: 582 RNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYY 641
+ EG I L+CKGAD+ + R+ + EL T H+ A +G RTL +A+K++ + Y
Sbjct: 555 KTQEGDILLFCKGADSAVFPRVQNHEIEL---TKVHVERNAMDGYRTLCVAFKEIAPDDY 611
Query: 642 EEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANI 701
E + ++A +A RE+++ +++++E NM L+GATA+EDKLQ ETI L A +
Sbjct: 612 ERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGL 671
Query: 702 KIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVG 761
K+WVLTGDK ETA + Y+C++ + TE+ +T T+ E + + E +++ + +
Sbjct: 672 KVWVLTGDKMETAKSTCYACRLFQTN-TELLELTTKTIEESERKEDRLHELLIEYRKKLL 730
Query: 762 NGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELE-------FLETACAC 814
+ F + T EY L+I+G +L+ L + + FL+ C
Sbjct: 731 HEFPKSTRSFKKAWTE-----HQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKC 785
Query: 815 KAVICCRVTPLQKAQVVELVKKYKKA-VTLAIGDGANDVSMIKTAHIGVGISGQEGIQAV 873
AV+CCR+ PLQKAQ+V +VK K + +TL+IGDGANDVSMI +H+G+GI G+EG QA
Sbjct: 786 TAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAA 845
Query: 874 LASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTV 933
SDYS +FK L++LLL HG Y+R+ + YFFYKN F + F + FFCGFS Q +
Sbjct: 846 RNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPL 905
Query: 934 YDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQ 993
YD ++T+YNI +TSLP+LA + +Q + P+LY N + F
Sbjct: 906 YDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFL 965
Query: 994 GIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAIN 1053
+ + FF Y +F A+ ++ ++ +F V T LV V++++ LDT +WT IN
Sbjct: 966 AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWTWIN 1025
Query: 1054 HFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMP 1113
HF IWGSLA Y + F+ G+ F Q R L+ + WL I+L + + P
Sbjct: 1026 HFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFISLFP 1083
Query: 1114 VVAFRFLR 1121
+ L+
Sbjct: 1084 EILLIVLK 1091
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 437 bits (1123), Expect = e-122
Identities = 335/1100 (30%), Positives = 530/1100 (48%), Gaps = 146/1100 (13%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
+Y N I KYN TFLP LF QF+ N YFL L Q +P++ + +T VPL
Sbjct: 52 RYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGF 111
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNR-QSQVLINGILQQEQWMNVCVGDIIKLENNQFVA 179
VL +T +++A ++ + D +VN++ S++ G ++ + N+ VGD+I +E NQ V
Sbjct: 112 VLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKS-SNIQVGDLIIVEKNQRVP 170
Query: 180 ADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNN 239
AD++ L +SE +G C++ T +LDGET+ K+R + T L + L + V E PN
Sbjct: 171 ADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNI 230
Query: 240 KLDKFSGTLYWKENKFPLSN----QNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 295
+ F GT +++ P+S +N L G V+ + G+V++ G + + + N+
Sbjct: 231 DIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASGT-VVGVVLYTGRELRSVMNTSNP 289
Query: 296 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFS 355
+ K D +N L +FG LV + +++ +H G W
Sbjct: 290 RSKIGLFDLEVNCLTKILFGALVVVSLVMVA----LQHFAGR-------W---------- 328
Query: 356 GFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEE 415
+L ++++ + ++PISL V++++ ++ +S+ I D K+ R++T+ E+
Sbjct: 329 -YLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI------PGTVVRSSTIPEQ 381
Query: 416 LGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYG--DVFDVLGHKAELGERPEPVDFSFNP 473
LG++ Y+ +DKTGTLTQN M+F + + +YG + +V H + + S +P
Sbjct: 382 LGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQQ-----SQDP 436
Query: 474 LADKKFLFWDPSLLEAVK-IGDPHTHEFFRLLSLCHTVMSEEKNEGEL------------ 520
A K P+L V+ HE + ++LCH V ++ G
Sbjct: 437 PAQK-----GPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDS 491
Query: 521 --YYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAI-TYQLLAILDFNNIRKRM 577
Y+A SPDE ALV + G R ++ + G I + +L I F KRM
Sbjct: 492 CRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRM 551
Query: 578 SVIVRNPE-GKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAG----EGLRTLVLA 632
+IVR+ G+I Y KGAD ++ + ++ D L E G EGLR LV+A
Sbjct: 552 GIIVRDESTGEITFYMKGADVVMAGIVQYN---------DWLEEECGNMAREGLRVLVVA 602
Query: 633 YKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPET 692
K L EE Y+++ R +QA L+ R ++A++ E +E M LL T +ED+LQ V T
Sbjct: 603 KKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPT 662
Query: 693 IALLTLANIKIWVLTGDKQETAVNIGYSCKMLT--DDMTEVFIVTGHTVLEVREELRKAR 750
+ L A IK+W+LTGDK ETA + ++T D+ +VT E EL R
Sbjct: 663 LETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRG--EAHLELNAFR 720
Query: 751 EKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELEFLET 810
K + ALVI+G SL L+ E EF+E
Sbjct: 721 RKH-------------------------------DCALVISGDSLEVCLKY-YEYEFMEL 748
Query: 811 ACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGI 870
AC C AV+CCR P QKAQ+V L+++ +T A+GDG NDVSMI+ + GVG+ G+EG
Sbjct: 749 ACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGK 808
Query: 871 QAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSA 930
QA LA+D+S +QFK L RLL+VHGR SY R + +++ + + F F++
Sbjct: 809 QASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFAS 868
Query: 931 QTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFIC 990
+Y + I Y+ +YT PV ++ V D+DV + +M YP+LY+ + + F I
Sbjct: 869 VPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIW 927
Query: 991 IAQGIYT-SVLMFFIPYGVFADATRDDGTQLADYQSFAVTVA---TSLVIVVSVQIGLDT 1046
+ IY S +M+ G L F VA TSL++ + + L
Sbjct: 928 VLISIYQGSTIMY--------------GALLLFESEFVHIVAISFTSLILTELLMVALTI 973
Query: 1047 GYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLT 1106
W + SLA Y A L +H D++ F+ +W V+T
Sbjct: 974 QTWHWLMTVAELLSLACYIASLVFLHE--FIDVY-----FIATLS------FLWKVSVIT 1020
Query: 1107 TVVCIMPVVAFRFLRLNLKP 1126
V C +P+ ++LR P
Sbjct: 1021 LVSC-LPLYVLKYLRRRFSP 1039
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 432 bits (1112), Expect = e-121
Identities = 243/622 (39%), Positives = 367/622 (59%), Gaps = 34/622 (5%)
Query: 519 ELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVH-EMGTAITYQLLAILDFNNIRKRM 577
E Y+A+SPDE ALV AA + F SRTP+ +TV GT +T+ LL L F+++RKRM
Sbjct: 714 EFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRM 773
Query: 578 SVIVRNP-EGKIRLYCKGADTILLDRLHHST-----------QELLNTTMDHLNEYAGEG 625
SV+VR+P G+I +Y KGAD++++D L +++ T HL+ YA +G
Sbjct: 774 SVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDG 833
Query: 626 LRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKL 685
LRTL +A K + EE + WA R +A + D+R++ L + +EN + LLGAT IED+L
Sbjct: 834 LRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRL 893
Query: 686 QQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGH-----TVL 740
Q+GVP+TIA L A I++WVLTGDKQETAVNI +SC++L T I T + ++L
Sbjct: 894 QEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESIL 953
Query: 741 EVR-EELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHAL 799
EEL++ RE + G +L S + EAV E LVI+G +L
Sbjct: 954 NCALEELKQFRELQKPDRKLFGF------RLPSKTPSITSEAVVPEAGLVIDGKTLNAIF 1007
Query: 800 EADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAH 859
+ +E +FLE C++V+CCR TPLQK+ +V+LV+ + +TL+IGDGANDVSMI+ A
Sbjct: 1008 QGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAAD 1067
Query: 860 IGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVH 919
IG+GISGQEG+QAV++SD++ ++FK L++LLLVHG W Y R+ + + Y+ YKN + +
Sbjct: 1068 IGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLL 1127
Query: 920 FWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLN 979
FW+ FFCGFS+ T+ D + + +N+ +TSLP L GV D+D+ + + P+LY+ GQ +
Sbjct: 1128 FWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNS 1187
Query: 980 LLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVS 1039
+N F+I + Y S++ FFIPY + + D +F + T + +
Sbjct: 1188 ECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSD-------IDVFTFGTPINTISLTTIL 1240
Query: 1040 VQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTV 1099
+ ++ WT + + GS +YF + ++ + P +V Q L+ PT
Sbjct: 1241 LHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQ--LSNPTF 1298
Query: 1100 WLTIVLTTVVCIMPVVAFRFLR 1121
+L LT VV ++P F L+
Sbjct: 1299 YLVCFLTPVVALLPRYFFLSLQ 1320
Score = 294 bits (752), Expect = 4e-79
Identities = 158/400 (39%), Positives = 243/400 (60%), Gaps = 22/400 (5%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
+Y N T+KY + TFLP NLFEQF AN YFLFL+IL +P + T++PL +
Sbjct: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124
Query: 121 VLTITAVKDATDDYFRHKSDNQVN-------NRQSQVLINGILQQEQWMNVCVGDIIKLE 173
VL + +KD +D+ RH+ D +N R+ Q + Q+ W +V VGD I+++
Sbjct: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYV-----QKCWKDVRVGDFIQMK 179
Query: 174 NNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVI 233
N+ V AD+LLL SS+P+G+C++ETA LDGETN+K R + S+ + F ++
Sbjct: 180 CNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIV 239
Query: 234 CEPPNNKLDKFSGTL-YWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNS 292
CE PNN L+KF G + + + + +++LLRGC +RNTE G+VI+AG +TK M N+
Sbjct: 240 CEKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNN 299
Query: 293 GRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSA 352
++KR+ I+R MN + + G L+ M +I A+G++IW F+ + P+D +
Sbjct: 300 SGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGT----FEEHPPFDVPDANG 355
Query: 353 FF-----SGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEA 407
F GF F + II+L ++PISLYVS+E+++LG +F++ D ++ + +
Sbjct: 356 SFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQC 415
Query: 408 RTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSY 447
R + E+LGQ++YIFSDKTGTLT+N MVF +C+I G Y
Sbjct: 416 RALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEY 455
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 429 bits (1102), Expect = e-119
Identities = 254/650 (39%), Positives = 384/650 (59%), Gaps = 36/650 (5%)
Query: 513 EEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVH--EMGTAITYQLLAILDF 570
E+++E EL Y+A+SPDE ALV AAR + V R ++V +G +T++LL L F
Sbjct: 684 EQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGF 742
Query: 571 NNIRKRMSVIVRNP-EGKIRLYCKGADTILLDRLHHST---------QELLNTTMDHLNE 620
+++RKRMSV++R+P +I +Y KGAD++++D L + +++ + T ++LN
Sbjct: 743 DSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNV 802
Query: 621 YAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATA 680
YA EGLRTL +A + L +E Y W + L+A + ++ E+ L +E N+ LLGAT
Sbjct: 803 YAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATG 862
Query: 681 IEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVL 740
IED+LQ GVPETI+ L A ++IWVLTGDKQETAVNI Y+CK+L D E I T
Sbjct: 863 IEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHD--EEVITLNATSQ 920
Query: 741 EVREELR-------KAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGH 793
E L ++R ++ G + SS S A +LVI+G
Sbjct: 921 EACAALLDQCLCYVQSRGLQRAPEKTKGK---VSMRFSSLCPPSTSTASGRRPSLVIDGR 977
Query: 794 SLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVS 853
SLA+ALE ++E +FL A C++V+CCR TPLQK+ VV+LV+ KA+TLAIGDGANDVS
Sbjct: 978 SLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVS 1037
Query: 854 MIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNF 913
MI+ A +GVGISGQEG+QAV+ASD++ +F++L+RLL++HG W Y R+ + YFFYKN
Sbjct: 1038 MIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNT 1097
Query: 914 AFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLY 973
F + FWF FFCGFSA T+ DQ+++ +N++++SLP L GV D+DVP + P+LY
Sbjct: 1098 MFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLY 1157
Query: 974 EPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATS 1033
+ GQ + R F+ +A + S++ F IPY + D+ D ++ + T
Sbjct: 1158 KSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSN-------VDLFTWGTPIVTI 1210
Query: 1034 LVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNT 1093
++ + +G++T WT +N S+ ++F + +++ +P + Q
Sbjct: 1211 ALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVAL-IYNASCATCYPPSNPY-WTMQAL 1268
Query: 1094 LAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQLVRKKQK 1143
L P +LT ++T V ++P + FR L+ + P R QL RK +
Sbjct: 1269 LGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLAR--QLTRKSPR 1316
Score = 308 bits (790), Expect = 2e-83
Identities = 164/412 (39%), Positives = 248/412 (60%), Gaps = 20/412 (4%)
Query: 46 ERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQ 105
ERR R ++ A N +KT+KY +L+FLP NLFEQF AN YF+F+ +L +P
Sbjct: 48 ERRRRRGCAQH-----LADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPA 102
Query: 106 ISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNN-------RQSQVLINGILQQ 158
+++ + P++ +L ITA +D +DY RH+SD+++N+ R+ + +N
Sbjct: 103 VNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRF--- 159
Query: 159 EQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSE 218
W + VGD ++L N+ AD+LLLSSS+P GLC+IETA LDGETN+K RQ + SE
Sbjct: 160 --WKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSE 217
Query: 219 LGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFP-LSNQNMLLRGCVLRNTEWCFG 277
L F + CE PNN L +F G + K L +N+LLRGC LRNT+ G
Sbjct: 218 LVSEFNPLTFTSVIECEKPNNDLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVG 277
Query: 278 LVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGM 337
+VI+AG +TK + N+ ++KR+ ++R MN VLW LVCM + A+G+ +W
Sbjct: 278 IVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQE 337
Query: 338 RFQV-YLPWDEAVD-SAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKK 395
+ + Y+P + S + SF + II+L ++PISLYVS+E+++ YFIN D +
Sbjct: 338 KKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQ 397
Query: 396 MFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSY 447
++ + + + R + E+LGQ++YIFSDKTGTLT+N MVF +C+++G Y
Sbjct: 398 LYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEY 449
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 425 bits (1093), Expect = e-118
Identities = 252/691 (36%), Positives = 393/691 (56%), Gaps = 42/691 (6%)
Query: 520 LYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTA-ITYQLLAILDFNNIRKRMS 578
L Y+A+SPDE ALV AAR + RSRTP+ + V +T+QLL IL F+++RKRMS
Sbjct: 721 LCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGPLTFQLLHILPFDSVRKRMS 780
Query: 579 VIVRNP-EGKIRLYCKGADTILLDRLHHSTQE----------LLNTTMDHLNEYAGEGLR 627
V+VR+P ++ +Y KGAD+++++ L ++ + + T HL++YA +GLR
Sbjct: 781 VVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLR 840
Query: 628 TLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQ 687
TL +A K + + Y EW A + D+RE+ L +EN + LLGAT IED+LQ+
Sbjct: 841 TLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQE 900
Query: 688 GVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVT-------GHTVL 740
GVPE+I L A IKIW+LTGDKQETAVNI Y+CK+L D ++FI+ G +
Sbjct: 901 GVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPD-DKLFILNTQSKDACGMLMS 959
Query: 741 EVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYA-LVINGHSLAHAL 799
+ +EL+K + + + Q LS L + +G A L+I G +L AL
Sbjct: 960 TILKELQKKTQALPE-----------QVSLSEDLLQPPVPRDSGLRAGLIITGKTLEFAL 1008
Query: 800 EADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAH 859
+ ++ +FLE C+AV+CCR TPLQK++VV+LV+ + + +TLAIGDGANDVSMI+ A
Sbjct: 1009 QESLQKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVAD 1068
Query: 860 IGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVH 919
IG+G+SGQEG+QAV+ASD++ SQFK L +LLLVHG W Y R+ + YFFYKN A+ +
Sbjct: 1069 IGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLL 1128
Query: 920 FWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLN 979
FW+ FFCGFS ++ D + + +N+++TS P + GV ++DV + M+ P+LY GQ +
Sbjct: 1129 FWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKS 1188
Query: 980 LLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVS 1039
+ F+I + Y S++ FF+PY + + D +F + T+ + +V
Sbjct: 1189 EAYLPHTFWITLLDAFYQSLVCFFVPYFTYQGSD-------TDIFAFGNPLNTAALFIVL 1241
Query: 1040 VQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTV 1099
+ + +++ T I+ I GS+ YF + + P+ ++ Q + P
Sbjct: 1242 LHLVIESKSLTWIHLLVIIGSILSYFLFAIVFGAMCVTCNPPSNPYWI--MQEHMLDPVF 1299
Query: 1100 WLTIVLTTVVCIMPVVAFRFLRLNLKPD-LSDTVRYTQLVRKKQKAQHRCMRRVGRTGSR 1158
+L +LTT + ++P +R L+ +L P + + +L +++ + R G+
Sbjct: 1300 YLVCILTTSIALLPRFVYRVLQGSLFPSPILRAKHFDRLTPEERTKALKKWRGAGKMNQV 1359
Query: 1159 RSGYAFSHQEGFGELIMSGKNMRLSSLALSS 1189
S YA G M G + + + SS
Sbjct: 1360 TSKYANQSAGKSGRRPMPGPSAVFAMKSASS 1390
Score = 324 bits (831), Expect = 3e-88
Identities = 172/402 (42%), Positives = 252/402 (62%), Gaps = 18/402 (4%)
Query: 58 EKFQ--YASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTI 115
EKF Y +N I+T+KY +L F+P NLFEQF AN YFLFL++L +P + + T+
Sbjct: 65 EKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITM 124
Query: 116 VPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQ-------WMNVCVGD 168
+PLV+VLTI A+KD +DY ++K D Q+NN LI + +++ W +V VGD
Sbjct: 125 LPLVVVLTIIAIKDGLEDYRKYKIDKQINN-----LITKVYSRKEKKYIDRCWKDVTVGD 179
Query: 169 IIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKF 228
I+L N+ + AD++LL S++P G+C+IET+ LDGE+N+K RQ + +E KF
Sbjct: 180 FIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKF 239
Query: 229 DGEVICEPPNNKLDKFSGTL-YWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTK 287
+ CE PNN L +F G L + + + LS +N+LLRGC +RNTE G+V++AG +TK
Sbjct: 240 SSRIECESPNNDLSRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETK 299
Query: 288 LMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIW--EHEVGMRFQVYLPW 345
M N+ ++KR+ ++R NT VLW LV M + A+G+ IW +E F V P
Sbjct: 300 AMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMHFFNVPEP- 358
Query: 346 DEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPA 405
D + S +GF FW+ II+L ++PISLYVS+E+++LG YFI D + K +
Sbjct: 359 DGHIISPLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIV 418
Query: 406 EARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSY 447
+ R + E+LGQ++Y+FSDKTGTLT+N MVF +CS+ G Y
Sbjct: 419 QCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDY 460
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 423 bits (1087), Expect = e-118
Identities = 329/1098 (29%), Positives = 525/1098 (47%), Gaps = 119/1098 (10%)
Query: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
++ N IK KYN+ TF+P L+EQF+ N YFL + Q +P + +T PL
Sbjct: 129 KHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLGF 188
Query: 121 VLTITAVKDATDDYFRHKSDNQVNNR-QSQVLINGILQQEQWMNVCVGDIIKLENNQFVA 179
VL +T ++A D++ R + D +VN++ S++ + G +Q + ++ VGD+I +E NQ +
Sbjct: 189 VLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKS-SDIQVGDLIIVEKNQRIP 247
Query: 180 ADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNN 239
+D++ L +SE G C+I T +LDGET+ K++ A+ T +L + L V + P
Sbjct: 248 SDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQM 307
Query: 240 KLDKFSGTLYWKENKFP----LSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 295
+ F GT +++ P LS +N L ++ + G+VI+ G +T+ + N+
Sbjct: 308 DIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGT-VIGVVIYTGKETRSVMNTSNP 366
Query: 296 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFS 355
K K +D +N L +F LV + +++ VG PW
Sbjct: 367 KNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF----VG-------PW---------- 405
Query: 356 GFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEE 415
+ + + ++++ + ++PISL V++++ + + + + D+ + RT+T+ EE
Sbjct: 406 -YRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENI------PGTVVRTSTIPEE 458
Query: 416 LGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYG-DVFDVLGHKAELGERPEPVDFSFNPL 474
LG++ Y+ +DKTGTLTQN M+F + + SYG D D + N
Sbjct: 459 LGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNT 518
Query: 475 ADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTV---------MSEEKNEGEL----- 520
S + K HE + + LCH V ++EE E
Sbjct: 519 GSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFS 578
Query: 521 ----YYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHE-MGTAITYQLLAILDFNNIRK 575
Y+A SPDE ALV + G SR ++ + G +++ +L + F + K
Sbjct: 579 DENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESK 638
Query: 576 RMSVIVRNPE-GKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAG----EGLRTLV 630
RM VIVR+ +I Y KGAD + + ++ D L E G EGLRTLV
Sbjct: 639 RMGVIVRDESTAEITFYMKGADVAMSPIVQYN---------DWLEEECGNMAREGLRTLV 689
Query: 631 LAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVP 690
+A K L EE Y+++ R QA L+ R ++A++ E +E M LL T +ED+LQ V
Sbjct: 690 VAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVR 749
Query: 691 ETIALLTLANIKIWVLTGDKQETAVNIGYSCKML--TDDMTEVFIVTGHTVLEVREELRK 748
T+ +L A IKIW+LTGDK ETA I S ++ T D+ VT E EL
Sbjct: 750 PTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRG--EAHLELNA 807
Query: 749 AREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELEFL 808
R K + ALVI+G SL L+ E EF+
Sbjct: 808 FRRKH-------------------------------DCALVISGDSLEVCLKY-YEHEFV 835
Query: 809 ETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQE 868
E AC C AV+CCR +P QKA++V L++++ T AIGDG NDVSMI+ A G+GI G+E
Sbjct: 836 ELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKE 895
Query: 869 GIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGF 928
G QA LA+D+S +QF+ + RLL+VHGR SY R + ++ + + F F
Sbjct: 896 GKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYF 955
Query: 929 SAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFF 988
++ +Y + + Y +YT PV ++ V DQDV + +M YP+LY+ + + F
Sbjct: 956 ASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFL 1014
Query: 989 ICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGY 1048
I + IY ++ YG + +A SF + T L++V + + T +
Sbjct: 1015 IWVLISIYQGGILM---YGALVLFESEFVHVVA--ISFTALILTELLMVA---LTVRTWH 1066
Query: 1049 WTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTV 1108
W + F+ SL Y + L + N F + F + +W +T V
Sbjct: 1067 WLMVVAEFL--SLGCYVSSLAFL--NEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVV 1122
Query: 1109 VCIMPVVAFRFLRLNLKP 1126
C +P+ ++LR L P
Sbjct: 1123 SC-LPLYVLKYLRRKLSP 1139
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 89.7 bits (221), Expect = 1e-17
Identities = 105/457 (22%), Positives = 186/457 (40%), Gaps = 70/457 (15%)
Query: 417 GQVEYIFSDKTGTLTQN-IMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLA 475
GQ+ + DKTGTLT++ + ++ S + + + +V +A + PL
Sbjct: 478 GQLNLVCFDKTGTLTRDGLDLWGVVSCDRNGFQEVHSFASGQA----------LPWGPLC 527
Query: 476 DKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTA 535
LL+ GDP + F E + A S D+ +
Sbjct: 528 AAMASCHSLILLDGTIQGDPLDLKMF---------------EATTWEMAFSGDDFHIKGV 572
Query: 536 ARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGA 595
+ V RT + V G AI +Q F++ +RM+VIV+ G + KGA
Sbjct: 573 PAHAMVVKPCRTASQVPVE--GIAILHQF----PFSSALQRMTVIVQEMGGDRLAFMKGA 626
Query: 596 DTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQ 655
+ T + + + L Y +G R + LAYK L+ +++ R
Sbjct: 627 PERVASFCQPET--VPTSFVSELQIYTTQGFRVIALAYKKLENDHHATTLTR-------- 676
Query: 656 DSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAV 715
E VE++++ LG +E++L++ + L A I+ ++TGD +TA+
Sbjct: 677 -----------ETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAI 725
Query: 716 NIGYSCKMLTDDMTEVFI----VTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLS 771
+ M+++ + I TG + + L + ++ +M ++ N +D++S
Sbjct: 726 TVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQD--NYINIRDEVS 783
Query: 772 SSKLTSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVV 831
+ G Y + G S H + L I R++P QK+ +V
Sbjct: 784 D-------KGREGSYHFALTGKSF-HVI--SQHFSSLLPKILINGTIFARMSPGQKSSLV 833
Query: 832 ELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQE 868
E +K V + GDGAND +K AH+G+ +S QE
Sbjct: 834 EEFQKLDYFVGMC-GDGANDCGALKMAHVGISLSEQE 869
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 81.3 bits (199), Expect = 5e-15
Identities = 146/597 (24%), Positives = 223/597 (37%), Gaps = 150/597 (25%)
Query: 344 PWDEAVDSAFFSGFLSFWSY-IIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKR 402
PW + F+ F+ I +L VP L ++V I L +S KKM MK
Sbjct: 393 PWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAV-TISLAYSV-----KKM--MKDN 444
Query: 403 TPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGE 462
R E +G I SDKTGTLT N M + I G Y +
Sbjct: 445 NLV--RHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQI------------ 490
Query: 463 RPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYY 522
P P F L ++ + I +T + ++ EK EG L
Sbjct: 491 -PSPDVFLPKVL---------DLIVNGISINSAYTSK----------ILPPEK-EGGLPR 529
Query: 523 KAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVR 582
+ + E AL+ GFV + +E+ Y+ + FN++RK MS ++R
Sbjct: 530 QVGNKTECALL------GFVTDLKQDYQAVRNEVPEEKLYK---VYTFNSVRKSMSTVIR 580
Query: 583 NPEGKIRLYCKGADTILLDRLHH--------------STQELLNTTMDHLNEYAGEGLRT 628
NP G R+Y KGA I+L + + +++ T ++ + A +GLRT
Sbjct: 581 NPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPM---ACDGLRT 637
Query: 629 LVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQG 688
+ +AY+D D+ W E+ + + IED ++
Sbjct: 638 ICIAYRDFDDT-EPSWDNE-------------------NEILTELTCIAVVGIEDPVRPE 677
Query: 689 VPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLT--DDMTEVFIVTGHTVLEVREEL 746
VP+ IA A I + ++TGD TA I C +LT DD LE +E
Sbjct: 678 VPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDF---------LCLEGKEFN 728
Query: 747 RKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELE 806
R R + G Q+KL K+ L LA + D
Sbjct: 729 RLIRNE---------KGEVEQEKL--DKIWPKLRV-------------LARSSPTDKH-- 762
Query: 807 FLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIG--VGI 864
L K + V ++++ V + GDG ND +K A +G +GI
Sbjct: 763 -----------------TLVKGIIDSTVGEHRQVVAVT-GDGTNDGPALKKADVGFAMGI 804
Query: 865 SGQEGIQAVLASDYSFSQFKFLQRL-LLVHGRWSYLRMCKFLCYFFYKNFAFTMVHF 920
+G + A ASD + F + ++ GR Y + KFL + N +V F
Sbjct: 805 AGTD--VAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 859
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 81.3 bits (199), Expect = 5e-15
Identities = 146/597 (24%), Positives = 223/597 (37%), Gaps = 150/597 (25%)
Query: 344 PWDEAVDSAFFSGFLSFWSY-IIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKR 402
PW + F+ F+ I +L VP L ++V I L +S KKM MK
Sbjct: 393 PWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAV-TISLAYSV-----KKM--MKDN 444
Query: 403 TPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGE 462
R E +G I SDKTGTLT N M + I G Y +
Sbjct: 445 NLV--RHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQI------------ 490
Query: 463 RPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYY 522
P P F L ++ + I +T + ++ EK EG L
Sbjct: 491 -PSPDVFLPKVL---------DLIVNGISINSAYTSK----------ILPPEK-EGGLPR 529
Query: 523 KAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVR 582
+ + E AL+ GFV + +E+ Y+ + FN++RK MS ++R
Sbjct: 530 QVGNKTECALL------GFVTDLKQDYQAVRNEVPEEKLYK---VYTFNSVRKSMSTVIR 580
Query: 583 NPEGKIRLYCKGADTILLDRLHH--------------STQELLNTTMDHLNEYAGEGLRT 628
NP G R+Y KGA I+L + + +++ T ++ + A +GLRT
Sbjct: 581 NPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPM---ACDGLRT 637
Query: 629 LVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQG 688
+ +AY+D D+ W E+ + + IED ++
Sbjct: 638 ICIAYRDFDDT-EPSWDNE-------------------NEILTELTCIAVVGIEDPVRPE 677
Query: 689 VPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLT--DDMTEVFIVTGHTVLEVREEL 746
VP+ IA A I + ++TGD TA I C +LT DD LE +E
Sbjct: 678 VPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDF---------LCLEGKEFN 728
Query: 747 RKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELE 806
R R + G Q+KL K+ L LA + D
Sbjct: 729 RLIRNE---------KGEVEQEKL--DKIWPKLRV-------------LARSSPTDKH-- 762
Query: 807 FLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIG--VGI 864
L K + V ++++ V + GDG ND +K A +G +GI
Sbjct: 763 -----------------TLVKGIIDSTVGEHRQVVAVT-GDGTNDGPALKKADVGFAMGI 804
Query: 865 SGQEGIQAVLASDYSFSQFKFLQRL-LLVHGRWSYLRMCKFLCYFFYKNFAFTMVHF 920
+G + A ASD + F + ++ GR Y + KFL + N +V F
Sbjct: 805 AGTD--VAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 859
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 77.8 bits (190), Expect = 6e-14
Identities = 107/476 (22%), Positives = 187/476 (39%), Gaps = 66/476 (13%)
Query: 417 GQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG-HKAELGERPEPVDFSFNPLA 475
GQ+ + DKTGTLT+ D D+ G + E P + N +
Sbjct: 490 GQLNLVCFDKTGTLTE----------------DGLDLWGIQRVENARFLSPEENVCNEML 533
Query: 476 DKKFLF------WDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDE 529
K + +E V GDP + F + ++ E E + P
Sbjct: 534 VKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGW---ILEEATEEETALHNRIMP-- 588
Query: 530 GALVTAARNFGFVFRSRTP---KTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRN-PE 585
T R + TP + + + E+ ++ F++ +RMSV+ R +
Sbjct: 589 ----TVVRPPKQLLPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGD 644
Query: 586 GKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWA 645
K+ Y KGA + T + + L ++ +G R + LA++ L
Sbjct: 645 RKMDAYMKGAPEAIAGLCKPETVPV--DFQNVLEDFTKQGFRVIALAHRKL--------- 693
Query: 646 ERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWV 705
E +L Q+ D +ENNM +G +++KL+Q P + L ANI+ +
Sbjct: 694 ESKLTWHKVQNISRDA-------IENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVM 746
Query: 706 LTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFT 765
+TGD TAV++ C M+ + + ++ + ++ K DS +
Sbjct: 747 VTGDSMLTAVSVARDCGMI---LPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSA 803
Query: 766 YQDKLSSSKLT--SVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVT 823
+ KL S+ + Y +NG S + LE + L + R+
Sbjct: 804 IDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILE---HFQDLVPKLMLHGTVFARMA 860
Query: 824 PLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYS 879
P QK Q++E ++ V + GDGAND +K AH G+ +S ++A +AS ++
Sbjct: 861 PDQKTQLIEALQNVDYFVGMC-GDGANDCGALKRAHGGISLS---ELEASVASPFT 912
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 74.3 bits (181), Expect = 7e-13
Identities = 186/853 (21%), Positives = 315/853 (36%), Gaps = 192/853 (22%)
Query: 115 IVPLVLVLTITAVKD-ATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLE 173
++ ++ V+ +TA D + + FR ++ V+ NG L Q + VGDI +++
Sbjct: 161 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVK 220
Query: 174 NNQFVAADLLLLSSSEPHGLCYIETAELDGETN-----------------------MKVR 210
+ AD +L+ +++ I+ + L GE++ V
Sbjct: 221 YGDLLPADGVLIQAND----LKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVV 276
Query: 211 QAIPVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLR 270
A+ V S+ G I L GE E + K + G + + K + + + L+
Sbjct: 277 TAVGVNSQTGIIFTLLGAGGEEE-EKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLK 335
Query: 271 NTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAI 330
+ E + + + + K +++ + + L + I + M I I +
Sbjct: 336 SAEG-------GEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVL 388
Query: 331 WEHEVGMRFQVY-LPWDEAVDSAFFSGFLSFWSY-IIILNTVVPISLYVSVEVIRLGHSY 388
+ V F V W + F+ F+ + +L VP L ++V I L +S
Sbjct: 389 YF--VIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAV-TISLAYSV 445
Query: 389 FINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYG 448
KKM MK R E +G I SDKTGTLT N M + + Y
Sbjct: 446 -----KKM--MKDNNLV--RHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYK 496
Query: 449 DVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCH 508
++ A P+ +D L+ A+ I +T +
Sbjct: 497 EI------PAPSALTPKILDL----------------LVHAISINSAYTTK--------- 525
Query: 509 TVMSEEKNEGELYYKAQSPDEGALVTAARNFGFVF---RSRTPKTITVHEMGTAITYQLL 565
++ EK EG L + + E AL+ GFV R P + E +L
Sbjct: 526 -ILPPEK-EGALPRQVGNKTECALL------GFVLDLKRDFQPVREQIPED------KLY 571
Query: 566 AILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDR---LHHSTQELL--------NTT 614
+ FN++RK MS ++R P+G RL+ KGA ILL + + +S EL +
Sbjct: 572 KVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMV 631
Query: 615 MDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMM 674
+ A +GLRT+ +AY+D +W EV ++
Sbjct: 632 RKIIEPMACDGLRTICIAYRDFSAGQEPDWDNE-------------------NEVVGDLT 672
Query: 675 LLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIV 734
+ IED ++ VPE I A I + ++TGD TA I C ++ E F+
Sbjct: 673 CIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPG--EDFL- 729
Query: 735 TGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHS 794
LE +E R+ R +
Sbjct: 730 ----CLEGKEFNRRIRNE------------------------------------------ 743
Query: 795 LAHALEADMELEFLETACACKAVICCRVTPLQK----AQVVELVKKYKKAVTLAIGDGAN 850
+ ++E E L+ K + R +P K +++ ++ V GDG N
Sbjct: 744 -----KGEIEQERLDKVWP-KLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTN 797
Query: 851 DVSMIKTAHIG--VGISGQEGIQAVLASDYSFSQFKFLQRL-LLVHGRWSYLRMCKFLCY 907
D +K A +G +GI+G + A ASD + F + ++ GR Y + KFL +
Sbjct: 798 DGPALKKADVGFAMGIAGTD--VAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 855
Query: 908 FFYKNFAFTMVHF 920
N +V F
Sbjct: 856 QLTVNVVAVIVAF 868
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 74.3 bits (181), Expect = 7e-13
Identities = 186/853 (21%), Positives = 315/853 (36%), Gaps = 192/853 (22%)
Query: 115 IVPLVLVLTITAVKD-ATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLE 173
++ ++ V+ +TA D + + FR ++ V+ NG L Q + VGDI +++
Sbjct: 161 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVK 220
Query: 174 NNQFVAADLLLLSSSEPHGLCYIETAELDGETN-----------------------MKVR 210
+ AD +L+ +++ I+ + L GE++ V
Sbjct: 221 YGDLLPADGVLIQAND----LKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVV 276
Query: 211 QAIPVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLR 270
A+ V S+ G I L GE E + K + G + + K + + + L+
Sbjct: 277 TAVGVNSQTGIIFTLLGAGGEEE-EKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLK 335
Query: 271 NTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAI 330
+ E + + + + K +++ + + L + I + M I I +
Sbjct: 336 SAEG-------GEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVL 388
Query: 331 WEHEVGMRFQVY-LPWDEAVDSAFFSGFLSFWSY-IIILNTVVPISLYVSVEVIRLGHSY 388
+ V F V W + F+ F+ + +L VP L ++V I L +S
Sbjct: 389 YF--VIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAV-TISLAYSV 445
Query: 389 FINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYG 448
KKM MK R E +G I SDKTGTLT N M + + Y
Sbjct: 446 -----KKM--MKDNNLV--RHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYK 496
Query: 449 DVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCH 508
++ A P+ +D L+ A+ I +T +
Sbjct: 497 EI------PAPSALTPKILDL----------------LVHAISINSAYTTK--------- 525
Query: 509 TVMSEEKNEGELYYKAQSPDEGALVTAARNFGFVF---RSRTPKTITVHEMGTAITYQLL 565
++ EK EG L + + E AL+ GFV R P + E +L
Sbjct: 526 -ILPPEK-EGALPRQVGNKTECALL------GFVLDLKRDFQPVREQIPED------KLY 571
Query: 566 AILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDR---LHHSTQELL--------NTT 614
+ FN++RK MS ++R P+G RL+ KGA ILL + + +S EL +
Sbjct: 572 KVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMV 631
Query: 615 MDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMM 674
+ A +GLRT+ +AY+D +W EV ++
Sbjct: 632 RKIIEPMACDGLRTICIAYRDFSAGQEPDWDNE-------------------NEVVGDLT 672
Query: 675 LLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIV 734
+ IED ++ VPE I A I + ++TGD TA I C ++ E F+
Sbjct: 673 CIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPG--EDFL- 729
Query: 735 TGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHS 794
LE +E R+ R +
Sbjct: 730 ----CLEGKEFNRRIRNE------------------------------------------ 743
Query: 795 LAHALEADMELEFLETACACKAVICCRVTPLQK----AQVVELVKKYKKAVTLAIGDGAN 850
+ ++E E L+ K + R +P K +++ ++ V GDG N
Sbjct: 744 -----KGEIEQERLDKVWP-KLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTN 797
Query: 851 DVSMIKTAHIG--VGISGQEGIQAVLASDYSFSQFKFLQRL-LLVHGRWSYLRMCKFLCY 907
D +K A +G +GI+G + A ASD + F + ++ GR Y + KFL +
Sbjct: 798 DGPALKKADVGFAMGIAGTD--VAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 855
Query: 908 FFYKNFAFTMVHF 920
N +V F
Sbjct: 856 QLTVNVVAVIVAF 868
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 72.4 bits (176), Expect = 2e-12
Identities = 144/660 (21%), Positives = 249/660 (37%), Gaps = 144/660 (21%)
Query: 115 IVPLVLVLTITAVKD-ATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLE 173
++ +V V+ +TA D + + FR ++ V+ G + Q ++ VGDI +++
Sbjct: 160 LLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVK 219
Query: 174 NNQFVAADLLLLSSSEPHGLCYIETAELDGETN-----------------------MKVR 210
+ AD +L+ ++ I+ + L GE++ V
Sbjct: 220 YGDLLPADGILIQGND----LKIDESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVV 275
Query: 211 QAIPVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNML------- 263
A+ V S+ G I L GE + K +K + K+ + N+N
Sbjct: 276 TAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKN-----KKQDGAIENRNKAKAQDGAA 330
Query: 264 LRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVI 323
+ L++ E G D K + + K +++ + + L + I + M I
Sbjct: 331 MEMQPLKSEEGGDG-------DEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAI 383
Query: 324 LAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLSFWSY-IIILNTVVPISLYVSVEVI 382
I ++ + + PW + F+ F+ + +L VP L ++V I
Sbjct: 384 TVIILVLY-FVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAV-TI 441
Query: 383 RLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSI 442
L +S KKM MK R E +G I SDKTGTLT N M + I
Sbjct: 442 SLAYSV-----KKM--MKDNNLV--RHLDACETMGNATAICSDKTGTLTMNRMTVVQAYI 492
Query: 443 NGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFR 502
N Y V PEP N L+ L+ + + +T +
Sbjct: 493 NEKHYKKV-------------PEPEAIPPNILS---------YLVTGISVNCAYTSK--- 527
Query: 503 LLSLCHTVMSEEKNEG---ELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTA 559
++ EK G + K + G L+ R++ V R+ P+
Sbjct: 528 -------ILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDV-RNEIPEEA-------- 571
Query: 560 ITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDRLH--------------H 605
L + FN++RK MS +++N +G R++ KGA I+L +
Sbjct: 572 ----LYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPR 627
Query: 606 STQELLNTTMDHLNEYAGEGLRTLVLAYKDLDE-EYYEEWAERRLQASLAQDSREDRLAS 664
+++ T ++ + A EGLRT+ LA++D E EW D+ D
Sbjct: 628 DRDDIVKTVIEPM---ASEGLRTICLAFRDFPAGEPEPEW-----------DNEND---- 669
Query: 665 IYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKML 724
+ + + IED ++ VP+ I A I + ++TGD TA I C +L
Sbjct: 670 ----IVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGIL 725
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 72.4 bits (176), Expect = 2e-12
Identities = 144/660 (21%), Positives = 249/660 (37%), Gaps = 144/660 (21%)
Query: 115 IVPLVLVLTITAVKD-ATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLE 173
++ +V V+ +TA D + + FR ++ V+ G + Q ++ VGDI +++
Sbjct: 160 LLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVK 219
Query: 174 NNQFVAADLLLLSSSEPHGLCYIETAELDGETN-----------------------MKVR 210
+ AD +L+ ++ I+ + L GE++ V
Sbjct: 220 YGDLLPADGILIQGND----LKIDESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVV 275
Query: 211 QAIPVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNML------- 263
A+ V S+ G I L GE + K +K + K+ + N+N
Sbjct: 276 TAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKN-----KKQDGAIENRNKAKAQDGAA 330
Query: 264 LRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVI 323
+ L++ E G D K + + K +++ + + L + I + M I
Sbjct: 331 MEMQPLKSEEGGDG-------DEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAI 383
Query: 324 LAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLSFWSY-IIILNTVVPISLYVSVEVI 382
I ++ + + PW + F+ F+ + +L VP L ++V I
Sbjct: 384 TVIILVLY-FVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAV-TI 441
Query: 383 RLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSI 442
L +S KKM MK R E +G I SDKTGTLT N M + I
Sbjct: 442 SLAYSV-----KKM--MKDNNLV--RHLDACETMGNATAICSDKTGTLTMNRMTVVQAYI 492
Query: 443 NGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFR 502
N Y V PEP N L+ L+ + + +T +
Sbjct: 493 NEKHYKKV-------------PEPEAIPPNILS---------YLVTGISVNCAYTSK--- 527
Query: 503 LLSLCHTVMSEEKNEG---ELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTA 559
++ EK G + K + G L+ R++ V R+ P+
Sbjct: 528 -------ILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDV-RNEIPEEA-------- 571
Query: 560 ITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDRLH--------------H 605
L + FN++RK MS +++N +G R++ KGA I+L +
Sbjct: 572 ----LYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPR 627
Query: 606 STQELLNTTMDHLNEYAGEGLRTLVLAYKDLDE-EYYEEWAERRLQASLAQDSREDRLAS 664
+++ T ++ + A EGLRT+ LA++D E EW D+ D
Sbjct: 628 DRDDIVKTVIEPM---ASEGLRTICLAFRDFPAGEPEPEW-----------DNEND---- 669
Query: 665 IYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKML 724
+ + + IED ++ VP+ I A I + ++TGD TA I C +L
Sbjct: 670 ----IVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGIL 725
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
sapiens]
Length = 1198
Score = 71.2 bits (173), Expect = 6e-12
Identities = 99/393 (25%), Positives = 156/393 (39%), Gaps = 83/393 (21%)
Query: 344 PWDEAVDSAFFSGFLSFWSY-IIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKR 402
PW + F+ F+ + +L VP L ++V I L +S KKM MK
Sbjct: 382 PWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAV-TISLAYSV-----KKM--MKDN 433
Query: 403 TPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGE 462
R E +G I SDKTGTLT N M + + GDV H E+
Sbjct: 434 NLV--RHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV-----GDV-----HYKEI-- 479
Query: 463 RPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYY 522
P+P + + L+ A+ I +T + ++ EK EG L
Sbjct: 480 -PDPSSINTKTME---------LLINAIAINSAYTTK----------ILPPEK-EGALPR 518
Query: 523 KAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVR 582
+ + E L+ GFV + +M Y+ + FN++RK MS +++
Sbjct: 519 QVGNKTECGLL------GFVLDLKQDYEPVRSQMPEEKLYK---VYTFNSVRKSMSTVIK 569
Query: 583 NPEGKIRLYCKGADTILLDR----LHHSTQELLNTTMDH-------LNEYAGEGLRTLVL 631
P+ R+Y KGA I+L + L+ + + + D + A +GLRT+ +
Sbjct: 570 LPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICV 629
Query: 632 AYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPE 691
AY+D +W D+ D L N + + IED ++ VPE
Sbjct: 630 AYRDFPSSPEPDW-----------DNENDIL--------NELTCICVVGIEDPVRPEVPE 670
Query: 692 TIALLTLANIKIWVLTGDKQETAVNIGYSCKML 724
I A I + ++TGD TA I C ++
Sbjct: 671 AIRKCQRAGITVRMVTGDNINTARAIAIKCGII 703
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
sapiens]
Length = 1243
Score = 71.2 bits (173), Expect = 6e-12
Identities = 99/393 (25%), Positives = 156/393 (39%), Gaps = 83/393 (21%)
Query: 344 PWDEAVDSAFFSGFLSFWSY-IIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKR 402
PW + F+ F+ + +L VP L ++V I L +S KKM MK
Sbjct: 427 PWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAV-TISLAYSV-----KKM--MKDN 478
Query: 403 TPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGE 462
R E +G I SDKTGTLT N M + + GDV H E+
Sbjct: 479 NLV--RHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV-----GDV-----HYKEI-- 524
Query: 463 RPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYY 522
P+P + + L+ A+ I +T + ++ EK EG L
Sbjct: 525 -PDPSSINTKTME---------LLINAIAINSAYTTK----------ILPPEK-EGALPR 563
Query: 523 KAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVR 582
+ + E L+ GFV + +M Y+ + FN++RK MS +++
Sbjct: 564 QVGNKTECGLL------GFVLDLKQDYEPVRSQMPEEKLYK---VYTFNSVRKSMSTVIK 614
Query: 583 NPEGKIRLYCKGADTILLDR----LHHSTQELLNTTMDH-------LNEYAGEGLRTLVL 631
P+ R+Y KGA I+L + L+ + + + D + A +GLRT+ +
Sbjct: 615 LPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICV 674
Query: 632 AYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPE 691
AY+D +W D+ D L N + + IED ++ VPE
Sbjct: 675 AYRDFPSSPEPDW-----------DNENDIL--------NELTCICVVGIEDPVRPEVPE 715
Query: 692 TIALLTLANIKIWVLTGDKQETAVNIGYSCKML 724
I A I + ++TGD TA I C ++
Sbjct: 716 AIRKCQRAGITVRMVTGDNINTARAIAIKCGII 748
>gi|66730421 ATPase type 13A5 [Homo sapiens]
Length = 1218
Score = 64.7 bits (156), Expect = 5e-10
Identities = 74/304 (24%), Positives = 127/304 (41%), Gaps = 37/304 (12%)
Query: 570 FNNIRKRMSVIVRNP-EGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRT 628
F++ +RMSVI + E +Y KGA ++ T + L Y +G R
Sbjct: 600 FSSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSET--VPKNFPQELRSYTVQGFRV 657
Query: 629 LVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQG 688
+ LA+K L + S + LA E+VE+ + LG +E++L++
Sbjct: 658 IALAHKTL---------------KMGNLSEVEHLAR--EKVESELTFLGLLIMENRLKKE 700
Query: 689 VPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRK 748
+ L+ A I+ ++TGD +TA+ + + +M+ ++V IV E E +
Sbjct: 701 TKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPG-SQVIIVEAD---EPEEFVPA 756
Query: 749 AREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGE----YALVINGHSLAHALEADME 804
+ + ++ G G K T GE Y ++G S +
Sbjct: 757 SVTWQLVENQETGPG-----KKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQ---H 808
Query: 805 LEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGI 864
L + R++P QK+ ++E +K V + GDGAND +K AH G+ +
Sbjct: 809 FNSLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMC-GDGANDCGALKAAHAGISL 867
Query: 865 SGQE 868
S QE
Sbjct: 868 SEQE 871
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
sapiens]
Length = 1023
Score = 63.9 bits (154), Expect = 9e-10
Identities = 168/743 (22%), Positives = 264/743 (35%), Gaps = 189/743 (25%)
Query: 146 RQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGET 205
+Q+ V+ NG V VGD+++++ + ADL ++S++ C ++ + L GE+
Sbjct: 167 QQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANG----CKVDNSSLTGES 222
Query: 206 NMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLR 265
EP D + EN N
Sbjct: 223 -----------------------------EPQTRSPD------FTNENPLETRNIAFFST 247
Query: 266 GCVLRNTEWCFGLVIFAGPDT---KLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGV 322
CV G+V++ G T ++ + + +T I + + I G V +GV
Sbjct: 248 NCVEGTAR---GIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGV 304
Query: 323 ILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVI 382
I + I E+ W EAV F G II+ N VP L +V V
Sbjct: 305 SFFILSLILEYT----------WLEAV--IFLIG-------IIVAN--VPEGLLATVTVC 343
Query: 383 RLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSI 442
+ + C+ K A E LG I SDKTGTLTQN M
Sbjct: 344 L---TLTAKRMARKNCLVKNLEAV-------ETLGSTSTICSDKTGTLTQNRMTV----- 388
Query: 443 NGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFR 502
H + FD H+A+ E V F DK W R
Sbjct: 389 -AHMW---FDNQIHEADTTENQSGVSF------DKTSATW---------------LALSR 423
Query: 503 LLSLCHTVMSEEKNEGELYYK---AQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTA 559
+ LC+ + + E K A E AL+ +V EM
Sbjct: 424 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELC----------CGSVKEMRER 473
Query: 560 ITYQLLAILDFNNIRKRMSVIVRNP---EGKIRLYCKGADTILLDR-----LHHSTQ--- 608
Y + + FN+ K I +NP E + L KGA +LDR LH Q
Sbjct: 474 --YAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLD 531
Query: 609 -ELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYE 667
EL + + E G G R L + L +E + E Q +D I
Sbjct: 532 EELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGF---------QFDTDDVNFPI-- 580
Query: 668 EVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDD 727
+N+ +G ++ D + VP+ + A IK+ ++TGD TA I ++++
Sbjct: 581 ---DNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEG 637
Query: 728 MTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYA 787
V + + V ++ D+ V +G +D ++S +L +L+
Sbjct: 638 NETVEDIAARLNIPV------SQVNPRDAKACVVHGSDLKD-MTSEQLDDILKY------ 684
Query: 788 LVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGD 847
H+ ++ R +P QK +VE ++ + A+ GD
Sbjct: 685 -----HT---------------------EIVFARTSPQQKLIIVEGCQR-QGAIVAVTGD 717
Query: 848 GANDVSMIKTAHIGV--GISGQE 868
G ND +K A IGV GI+G +
Sbjct: 718 GVNDSPALKKADIGVAMGIAGSD 740
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,037,986
Number of Sequences: 37866
Number of extensions: 1738967
Number of successful extensions: 4330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 4033
Number of HSP's gapped (non-prelim): 174
length of query: 1223
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1109
effective length of database: 13,930,794
effective search space: 15449250546
effective search space used: 15449250546
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.