Guide to the Human Genome
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Search of human proteins with 40255178

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40255178 tudor domain containing 5 [Homo sapiens]
         (981 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40255178 tudor domain containing 5 [Homo sapiens]                 1966   0.0  
gi|112293287 tudor domain containing 7 [Homo sapiens]                  92   3e-18
gi|145312259 tudor and KH domain containing isoform a [Homo sapi...    84   8e-16
gi|145312246 tudor and KH domain containing isoform b [Homo sapi...    84   8e-16
gi|145312270 tudor and KH domain containing isoform a [Homo sapi...    84   8e-16
gi|145312256 tudor and KH domain containing isoform a [Homo sapi...    84   8e-16
gi|38505161 tudor domain containing 1 [Homo sapiens]                   80   7e-15
gi|169163653 PREDICTED: similar to tudor domain containing 1 [Ho...    79   2e-14
gi|169164192 PREDICTED: similar to tudor domain containing 1 [Ho...    79   2e-14
gi|169163210 PREDICTED: similar to tudor domain containing 1 [Ho...    79   2e-14
gi|58197558 tudor domain containing 6 [Homo sapiens]                   69   2e-11
gi|94421471 ring finger protein 17 [Homo sapiens]                      55   3e-07
gi|166851804 tudor domain containing 9 [Homo sapiens]                  46   1e-04
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]          46   2e-04
gi|77404397 staphylococcal nuclease domain containing 1 [Homo sa...    44   6e-04
gi|85797660 limkain b1 [Homo sapiens]                                  39   0.031
gi|161016765 tudor domain containing 12 [Homo sapiens]                 36   0.15 
gi|94421473 paternally expressed 10 isoform RF1 [Homo sapiens]         33   1.0  
gi|94421475 paternally expressed 10 isoform RF1/2 [Homo sapiens]       33   1.0  
gi|117606360 ADP-ribosylation factor guanine nucleotide factor 6...    33   1.3  
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]              33   1.7  
gi|82830424 gon-4-like isoform a [Homo sapiens]                        33   1.7  
gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]       33   1.7  
gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]        33   1.7  
gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]       33   1.7  
gi|45827771 autoantigen RCD8 [Homo sapiens]                            33   1.7  
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       32   2.2  
gi|87299628 biorientation of chromosomes in cell division 1-like...    32   2.2  
gi|55769554 protein tyrosine phosphatase, receptor type, f polyp...    32   2.2  
gi|160707881 formin 2 [Homo sapiens]                                   32   2.9  

>gi|40255178 tudor domain containing 5 [Homo sapiens]
          Length = 981

 Score = 1966 bits (5093), Expect = 0.0
 Identities = 981/981 (100%), Positives = 981/981 (100%)

Query: 1   MSEQERIQECLRKEIRSLLISTKDGLSPQELEKEYLLMVGNHLPLRILGYRSTMELVLDM 60
           MSEQERIQECLRKEIRSLLISTKDGLSPQELEKEYLLMVGNHLPLRILGYRSTMELVLDM
Sbjct: 1   MSEQERIQECLRKEIRSLLISTKDGLSPQELEKEYLLMVGNHLPLRILGYRSTMELVLDM 60

Query: 61  PDVVRVCPGAGGTVILKAIPDESTKGIASLVAKQRSSHKLRNSMHKGRPSIYSGPRSHRR 120
           PDVVRVCPGAGGTVILKAIPDESTKGIASLVAKQRSSHKLRNSMHKGRPSIYSGPRSHRR
Sbjct: 61  PDVVRVCPGAGGTVILKAIPDESTKGIASLVAKQRSSHKLRNSMHKGRPSIYSGPRSHRR 120

Query: 121 VPYRGRVAPILPAVVKSELKDLLALSPVLLSDFEKAFAKRFGRSFQYMQYGFLSMFEVLN 180
           VPYRGRVAPILPAVVKSELKDLLALSPVLLSDFEKAFAKRFGRSFQYMQYGFLSMFEVLN
Sbjct: 121 VPYRGRVAPILPAVVKSELKDLLALSPVLLSDFEKAFAKRFGRSFQYMQYGFLSMFEVLN 180

Query: 181 AASDVISVEQTRAGSLLMLKKSVTEEKPRGCPAGKIFTQPFRMKQGSYSTGFPVAKPCFS 240
           AASDVISVEQTRAGSLLMLKKSVTEEKPRGCPAGKIFTQPFRMKQGSYSTGFPVAKPCFS
Sbjct: 181 AASDVISVEQTRAGSLLMLKKSVTEEKPRGCPAGKIFTQPFRMKQGSYSTGFPVAKPCFS 240

Query: 241 QPTSNMEPPKQIMSMEKTSKLNVVETSRLNHTEKLNQLENTFKSVIAQIGPGGTISSELK 300
           QPTSNMEPPKQIMSMEKTSKLNVVETSRLNHTEKLNQLENTFKSVIAQIGPGGTISSELK
Sbjct: 241 QPTSNMEPPKQIMSMEKTSKLNVVETSRLNHTEKLNQLENTFKSVIAQIGPGGTISSELK 300

Query: 301 HKIKFVVSKFPEGLFISKLLGEYEVIFKEQLSPKKLGFLNVTELVGALSDILHVEFRKGH 360
           HKIKFVVSKFPEGLFISKLLGEYEVIFKEQLSPKKLGFLNVTELVGALSDILHVEFRKGH
Sbjct: 301 HKIKFVVSKFPEGLFISKLLGEYEVIFKEQLSPKKLGFLNVTELVGALSDILHVEFRKGH 360

Query: 361 QDLLVFDADKKPLPPVQSDKKIEAKACVSSPPRNSLSTAAVKETVWNCPSKKQKEPQQKI 420
           QDLLVFDADKKPLPPVQSDKKIEAKACVSSPPRNSLSTAAVKETVWNCPSKKQKEPQQKI
Sbjct: 361 QDLLVFDADKKPLPPVQSDKKIEAKACVSSPPRNSLSTAAVKETVWNCPSKKQKEPQQKI 420

Query: 421 CKKPNLVVKPLQLQVETNKSELNLAMANHDIPPDAVPNKKLCRLPPLDTSSLIGVFVEYI 480
           CKKPNLVVKPLQLQVETNKSELNLAMANHDIPPDAVPNKKLCRLPPLDTSSLIGVFVEYI
Sbjct: 421 CKKPNLVVKPLQLQVETNKSELNLAMANHDIPPDAVPNKKLCRLPPLDTSSLIGVFVEYI 480

Query: 481 ISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRISEDK 540
           ISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRISEDK
Sbjct: 481 ISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRISEDK 540

Query: 541 WWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVE 600
           WWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVE
Sbjct: 541 WWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVE 600

Query: 601 EHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVC 660
           EHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVC
Sbjct: 601 EHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVC 660

Query: 661 RENISSKGFSELNPLALYTTSSGGPEDIVLTELGYPSQQHYFNEDRKISPQSKESELRIL 720
           RENISSKGFSELNPLALYTTSSGGPEDIVLTELGYPSQQHYFNEDRKISPQSKESELRIL
Sbjct: 661 RENISSKGFSELNPLALYTTSSGGPEDIVLTELGYPSQQHYFNEDRKISPQSKESELRIL 720

Query: 721 DEIPTGMPCLESVTIGDDIWDENWLPLQAKMGKGGDAASHLFTASLGGKNQYSSCKEMPQ 780
           DEIPTGMPCLESVTIGDDIWDENWLPLQAKMGKGGDAASHLFTASLGGKNQYSSCKEMPQ
Sbjct: 721 DEIPTGMPCLESVTIGDDIWDENWLPLQAKMGKGGDAASHLFTASLGGKNQYSSCKEMPQ 780

Query: 781 KDWCFSTPKDTWDDSWQPSGLVNGTKVEVHKPEVLGAQEKNTGTNRTQKQLDINGSSDSS 840
           KDWCFSTPKDTWDDSWQPSGLVNGTKVEVHKPEVLGAQEKNTGTNRTQKQLDINGSSDSS
Sbjct: 781 KDWCFSTPKDTWDDSWQPSGLVNGTKVEVHKPEVLGAQEKNTGTNRTQKQLDINGSSDSS 840

Query: 841 TLPKLEEFCTSLTQSEQSADGSQSEPNNSQTQPKQIQLSTAAPCSTTAVDDSAEKPSGSV 900
           TLPKLEEFCTSLTQSEQSADGSQSEPNNSQTQPKQIQLSTAAPCSTTAVDDSAEKPSGSV
Sbjct: 841 TLPKLEEFCTSLTQSEQSADGSQSEPNNSQTQPKQIQLSTAAPCSTTAVDDSAEKPSGSV 900

Query: 901 ESSPEILKNEDFSSSRAITLYKDKRQESVDQLSLILSYECQISQKLYIPRSTATAALGAA 960
           ESSPEILKNEDFSSSRAITLYKDKRQESVDQLSLILSYECQISQKLYIPRSTATAALGAA
Sbjct: 901 ESSPEILKNEDFSSSRAITLYKDKRQESVDQLSLILSYECQISQKLYIPRSTATAALGAA 960

Query: 961 ARLATSRSLLHWYPSVKRMEA 981
           ARLATSRSLLHWYPSVKRMEA
Sbjct: 961 ARLATSRSLLHWYPSVKRMEA 981


>gi|112293287 tudor domain containing 7 [Homo sapiens]
          Length = 1098

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 165/710 (23%), Positives = 279/710 (39%), Gaps = 159/710 (22%)

Query: 9   ECLRKEIRSLLISTKDGLSPQELEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVRVCP 68
           + + K +R++L S K+G++   L+ EY  + G+ +P + LG+ +    +  +P VVR+  
Sbjct: 5   DLVSKMLRAVLQSHKNGVALPRLQGEYRSLTGDWIPFKQLGFPTLEAYLRSVPAVVRIET 64

Query: 69  GAGGTVILKAIPDESTKGIASLVAKQRSSHKLRNSMHKGRPSIYSGPRSHRRVPYRGRVA 128
              G +   A+    T  IA LVA+QRSS +                ++ R+V  + RV 
Sbjct: 65  SRSGEITCYAMACTETARIAQLVARQRSSKR----------------KTGRQVNCQMRVK 108

Query: 129 PILPAVVKSELKDLLALSPVLLSDFEKAFAKRFGRSFQYMQYGFLSMFEV--------LN 180
             +P  ++ + K  L                         Q GF S F V        L 
Sbjct: 109 KTMPFFLEGKPKATLR------------------------QPGFASNFSVGKKPNPAPLR 144

Query: 181 AASDVISVEQTRAGSLLMLKKSVTEEKPRGCPAGKIFTQPFRMKQGSYSTGFPVAKPCFS 240
              + + V+     S  ML  ++  E  +  P  +  T     +              FS
Sbjct: 145 DKGNSVGVKPDAEMSPYMLHTTLGNEAFKDIPVQRHVTMSTNNR--------------FS 190

Query: 241 QPTSNMEPPKQIMSMEKTSKLNVVETSRLNHT-EKLN---QLENTFKSVIAQIGPGGTIS 296
            P ++++PP Q M + +TS   +  +  LN T EK N       T+K             
Sbjct: 191 -PKASLQPPLQ-MHLSRTSTKEM--SDNLNQTVEKPNVKPPASYTYKM------------ 234

Query: 297 SELKHKIKFVVSKFPEGLFISKLLGEYEVIFKEQLSPKKLGFLNVTELVGALSDILHVEF 356
            E++++IK +++K   G++ISKL   Y+ ++KE L+    G L   E       I  VE 
Sbjct: 235 DEVQNRIKEILNKHNNGIWISKLPHFYKELYKEDLNQ---GILQQFE---HWPHICTVEK 288

Query: 357 R-KGHQDLLVF------------DADKKPLPPVQSDKKIEA-KAC---VSSPPRNSLSTA 399
              G QDLL++            D +K PL P+   K+    K C   ++   +  ++  
Sbjct: 289 PCSGGQDLLLYPAKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEKVADL 348

Query: 400 AVKET--VWNCPSKKQKEPQQKICKKPNLVVKPL-----------------------QLQ 434
            VK T  +W     K  E   K+ K P   +K L                       +L 
Sbjct: 349 LVKYTSGLWASALPKAFEEMYKV-KFPEDALKNLASLSDVCSIDYISGNPQKAILYAKLP 407

Query: 435 VETNKSELNLAMANHDIPPDAVPNKKLCRL-----------------PPL--DTSSLIGV 475
           + T+K + +   A+ D    A+  ++  ++                 PPL   T +   V
Sbjct: 408 LPTDKIQKDAGQAHGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPSV 467

Query: 476 FVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVR 535
            V  + + ++  IR   +D S   E M  EM+  YS     +  + P   +  G L  V 
Sbjct: 468 LVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSK----NPKITPVQAVNVGQLLAVN 523

Query: 536 ISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAW 595
             ED W    +I    E+ +++V Y D+G    V+KS    L   +  L  QA  C LA 
Sbjct: 524 AEEDAWLRAQVIST--EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAG 581

Query: 596 VRPVEEHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDV 645
           +  + +      +++    CG    V ++D+    I  + L DTS  +D+
Sbjct: 582 LEVLSDDPDLVKVVE-SLTCGKIFAVEILDK--ADIPLVVLYDTSGEDDI 628



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 19/181 (10%)

Query: 475  VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCV 534
            V+V     P  F I+ +       LE +M EM   YS  +  +R++     ++   +   
Sbjct: 916  VYVPVACHPGYFVIQPWQEIHK--LEVLMEEMILYYS--VSEERHIA----VEKDQVYAA 967

Query: 535  RISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLA 594
            ++ E+KW +RV++  +L    V V+  D+G   +V    ++ L   + KLP QA+   LA
Sbjct: 968  KV-ENKW-HRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLA 1025

Query: 595  WVRPVEEHWTSKAILQFQKLCGLKPLVGVVDEYV------DGILNIFLCDTS-SNEDVYF 647
             V+     W+ +A + F+     KPLV +V   +      D  + ++L DTS  + D + 
Sbjct: 1026 GVKC--NQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWI 1083

Query: 648  H 648
            H
Sbjct: 1084 H 1084



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 18/132 (13%)

Query: 518 RYVMPECFIQP---GHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSL 574
           +++  ECF+     G +C         W RV I  V   + ++V + D G +  V+ S L
Sbjct: 693 KHMTSECFVSLPFCGKICLFHCKGK--WLRVEITNVHSSRALDVQFLDSGTVTSVKVSEL 750

Query: 575 RFLKCCYTK----LPAQAIPCSLAWVRPVEEHWTSKAILQFQKL------CGLKPLVGVV 624
           R +   + +    +P QAI C LA +      WT  A+L  +        C +K  V  V
Sbjct: 751 REIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIK--VTKV 808

Query: 625 DEYVDGILNIFL 636
           DE   GI +++L
Sbjct: 809 DE-TRGIAHVYL 819


>gi|145312259 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 83.6 bits (205), Expect = 8e-16
 Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 18/221 (8%)

Query: 455 AVPNKKLCRLPPLDTSSLIGVFVEYIIS----PSQFYIRIYSRDSSELLEDMMIEMRRCY 510
           A+P   +  +P  D S     ++E  +S    P+ F+I+I    S +L + ++ EM + Y
Sbjct: 286 AIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQL-DKLVNEMTQHY 344

Query: 511 SNQLVSDRYVMPECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQ 570
            N +  D  V        G +    +  +  WYR  +   LE   +++++ DFG+ G   
Sbjct: 345 ENSVPEDLTV------HVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCP 398

Query: 571 KSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSKAILQFQKL---CGLKPLVGVVDEY 627
              LR L+  +  LP QAI CSLA + P  + W  +A+ +F +L      KPLV  +  Y
Sbjct: 399 LKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSY 458

Query: 628 VD-GIL---NIFLCDTSSNEDVYFHHVLRTEGHAIVCRENI 664
           V  GI     I+L DTS+ + +     L  +G+AI   E+I
Sbjct: 459 VQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDI 499


>gi|145312246 tudor and KH domain containing isoform b [Homo
           sapiens]
          Length = 516

 Score = 83.6 bits (205), Expect = 8e-16
 Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 18/221 (8%)

Query: 455 AVPNKKLCRLPPLDTSSLIGVFVEYIIS----PSQFYIRIYSRDSSELLEDMMIEMRRCY 510
           A+P   +  +P  D S     ++E  +S    P+ F+I+I    S +L + ++ EM + Y
Sbjct: 241 AIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQL-DKLVNEMTQHY 299

Query: 511 SNQLVSDRYVMPECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQ 570
            N +  D  V        G +    +  +  WYR  +   LE   +++++ DFG+ G   
Sbjct: 300 ENSVPEDLTV------HVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCP 353

Query: 571 KSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSKAILQFQKL---CGLKPLVGVVDEY 627
              LR L+  +  LP QAI CSLA + P  + W  +A+ +F +L      KPLV  +  Y
Sbjct: 354 LKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSY 413

Query: 628 VD-GIL---NIFLCDTSSNEDVYFHHVLRTEGHAIVCRENI 664
           V  GI     I+L DTS+ + +     L  +G+AI   E+I
Sbjct: 414 VQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDI 454


>gi|145312270 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 83.6 bits (205), Expect = 8e-16
 Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 18/221 (8%)

Query: 455 AVPNKKLCRLPPLDTSSLIGVFVEYIIS----PSQFYIRIYSRDSSELLEDMMIEMRRCY 510
           A+P   +  +P  D S     ++E  +S    P+ F+I+I    S +L + ++ EM + Y
Sbjct: 286 AIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQL-DKLVNEMTQHY 344

Query: 511 SNQLVSDRYVMPECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQ 570
            N +  D  V        G +    +  +  WYR  +   LE   +++++ DFG+ G   
Sbjct: 345 ENSVPEDLTV------HVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCP 398

Query: 571 KSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSKAILQFQKL---CGLKPLVGVVDEY 627
              LR L+  +  LP QAI CSLA + P  + W  +A+ +F +L      KPLV  +  Y
Sbjct: 399 LKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSY 458

Query: 628 VD-GIL---NIFLCDTSSNEDVYFHHVLRTEGHAIVCRENI 664
           V  GI     I+L DTS+ + +     L  +G+AI   E+I
Sbjct: 459 VQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDI 499


>gi|145312256 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 83.6 bits (205), Expect = 8e-16
 Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 18/221 (8%)

Query: 455 AVPNKKLCRLPPLDTSSLIGVFVEYIIS----PSQFYIRIYSRDSSELLEDMMIEMRRCY 510
           A+P   +  +P  D S     ++E  +S    P+ F+I+I    S +L + ++ EM + Y
Sbjct: 286 AIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQL-DKLVNEMTQHY 344

Query: 511 SNQLVSDRYVMPECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQ 570
            N +  D  V        G +    +  +  WYR  +   LE   +++++ DFG+ G   
Sbjct: 345 ENSVPEDLTV------HVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCP 398

Query: 571 KSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSKAILQFQKL---CGLKPLVGVVDEY 627
              LR L+  +  LP QAI CSLA + P  + W  +A+ +F +L      KPLV  +  Y
Sbjct: 399 LKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSY 458

Query: 628 VD-GIL---NIFLCDTSSNEDVYFHHVLRTEGHAIVCRENI 664
           V  GI     I+L DTS+ + +     L  +G+AI   E+I
Sbjct: 459 VQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDI 499


>gi|38505161 tudor domain containing 1 [Homo sapiens]
          Length = 1189

 Score = 80.5 bits (197), Expect = 7e-15
 Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 10/177 (5%)

Query: 467 LDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECF- 525
           L     + V V  I SP +FY  +   D+ + L D+   +      +L       P  F 
Sbjct: 710 LGVDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKL-------PNGFK 762

Query: 526 IQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLP 585
            + G  CC   + D  WYR ++  +L    V+V + D+GNI  V    LR +   +  LP
Sbjct: 763 AEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNLP 822

Query: 586 AQAIPCSLAWVRPVEEHWTSKAILQFQK-LCGLKPLVGVVDEYVDGILNIFLCDTSS 641
            Q I C LA ++   +HW+ +AI +FQ  + G+K    VV+   +GI  + L D S+
Sbjct: 823 FQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENGI-GVELTDLST 878



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 77/289 (26%), Positives = 120/289 (41%), Gaps = 34/289 (11%)

Query: 477 VEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRI 536
           V +I +P  F+ +     S   L ++   + + Y +QL       P      G +CC + 
Sbjct: 500 VAHIQTPEDFFCQ--QLQSGRKLAELQASLSK-YCDQLPPRSDFYPAI----GDICCAQF 552

Query: 537 SEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWV 596
           SED  WYR  +     ++ V V Y D+GN  I+    L  +     +LP QAI C LA V
Sbjct: 553 SEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGV 612

Query: 597 RPVEEHWTSKAILQFQKLCGLKPL-VGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEG 655
           +P    WT +AI   +KL   K + V VVD+  +  L + L D S    V    VL   G
Sbjct: 613 KPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSL-VELIDKSETPHVSVSKVLLDAG 671

Query: 656 HAIVCRENISSKGF------------SELNPLALYTTSSGGPE--DIVLTELGYPSQ--Q 699
            A+  +  ++ K               ++NPL       G  +  D+V+  +  P +   
Sbjct: 672 FAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVDQTVDVVVCVIYSPGEFYC 731

Query: 700 HYFNED--RKISPQSKESELRILDEIPT------GMPCLESVTIGDDIW 740
           H   ED  +K++  +K        ++P       G PC  +   GD  W
Sbjct: 732 HVLKEDALKKLNDLNKSLAEHCQQKLPNGFKAEIGQPCC-AFFAGDGSW 779



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 55/217 (25%), Positives = 102/217 (47%), Gaps = 18/217 (8%)

Query: 419 KICKKPNLVVKPLQLQVETNKSELNLAMANH-DIPPDAVPNKKLCRLPPLDTSSLIGVFV 477
           K+  K ++  K +++    NKS+  L +     I  + +    L  L    T  + G   
Sbjct: 215 KLENKSSIETKDVEVN---NKSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEIKGTVT 271

Query: 478 EYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRIS 537
           E+   P  FY+++YS +  E +  +   ++  Y+N  V ++  +P      G +C  + +
Sbjct: 272 EFK-HPGDFYVQLYSSEVLEYMNQLSASLKETYAN--VHEKDYIPV----KGEVCIAKYT 324

Query: 538 EDKWWYRVIIHRV-LEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWV 596
            D+ W R II  V +++++  V Y D+GN  I+  + +  L       P  AI C +A V
Sbjct: 325 VDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANV 384

Query: 597 RPVEEHWTSKAI-----LQFQKLCGLKPLVGVVDEYV 628
            P E +W+S  I     L  ++ C +K +V +++E V
Sbjct: 385 IPAEGNWSSDCIKATKPLLMEQYCSIK-IVDILEEEV 420



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 1/65 (1%)

Query: 529  GHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQA 588
            G  CC + + D +WYR ++    +  +VEV Y D+GNI  +    ++ +   +  LP Q 
Sbjct: 994  GDACCAKYTSDDFWYRAVVLGTSDT-DVEVLYADYGNIETLPLCRVQPITSSHLALPFQI 1052

Query: 589  IPCSL 593
            I CSL
Sbjct: 1053 IRCSL 1057


>gi|169163653 PREDICTED: similar to tudor domain containing 1 [Homo
           sapiens]
          Length = 2080

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 53/175 (30%), Positives = 95/175 (54%), Gaps = 14/175 (8%)

Query: 476 FVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVR 535
           F+ Y+++PS F++R  + D     +++M  + + Y +   +D  ++ +   +PG  CC R
Sbjct: 633 FIAYVLNPSNFWVR--TNDHRNEFQEIMKNINKFY-DLCENDEMILRKP--EPGLFCCAR 687

Query: 536 ISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAW 595
            S+D+ +YR +I  +    ++ V++ D+GN   +    ++ L   + +LPA A+ CSLA 
Sbjct: 688 YSKDRRFYRAVITEI-NGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAH 746

Query: 596 VRPVEEHWTSKAILQFQKLCGLKPLVGVV-----DEYVDGILNIFLCDTSSNEDV 645
           + PVE+ WT  AI  F+KL   K ++  V     D+Y    +NI   + S N DV
Sbjct: 747 IFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYT---VNIQSVEASENIDV 798



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 56/221 (25%), Positives = 95/221 (42%), Gaps = 29/221 (13%)

Query: 475  VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCV 534
            V++ +I SP +FY ++  R++ +L    MIE +   S  L +     P+       +C  
Sbjct: 1115 VYISHIYSPQKFYCQL-GRNNKDL---EMIETKITESVNLQN----FPKYDSNKMRVCIS 1166

Query: 535  RISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL---PAQAIPC 591
            +  ED   YR +        E +V++ DFGN  +V ++ LR +   + +L   P QAI C
Sbjct: 1167 KYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKC 1226

Query: 592  SLAWVRPVE-----EHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVY 646
             L+ +R V+       W     L      G      ++ +  DG L I L D S     Y
Sbjct: 1227 FLSDLRDVDIPAEISSWFKDNFL------GRSLKAIILSQESDGQLGIELYDGSQ----Y 1276

Query: 647  FHHVLRTEGHAI---VCRENISSKGFSELNPLALYTTSSGG 684
             +  ++   HA     C +    +  +++N    +TTS  G
Sbjct: 1277 INEKIKVLLHAYGKRHCDQACCMEKSNKINENKRFTTSLKG 1317



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 7/129 (5%)

Query: 465 PPLDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPEC 524
           P L   S   V V   +SPS+FY ++        LE++   M   Y       +   P C
Sbjct: 381 PSLSVGSTESVKVSSALSPSKFYCQLIKWTPE--LENLTAHMTLHYDTVC---QETSPTC 435

Query: 525 FIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL 584
                 L CV    +  W+R I+ ++L   +V++++ D+G+   +    ++ LK  +  +
Sbjct: 436 --DNFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILV 493

Query: 585 PAQAIPCSL 593
           P  + PCSL
Sbjct: 494 PLFSFPCSL 502



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 11/142 (7%)

Query: 494  DSSELLEDMMIEMRRCYSNQLVSDR----YVMPECFIQPGHLCCVRISEDKWWYRVIIHR 549
            D S  LED    M+  Y   L+SD       +P+ FI PG  C  +   +  W RV I  
Sbjct: 1893 DFSIQLEDFFDIMK--YLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISE 1950

Query: 550  VLEKQEVEVFYPDFGNIGIVQKSSLRFLKCC---YTKLPAQAIPCSLAWVRPVE-EHWTS 605
            V   Q + +   D+G    ++ S +  LK        LP  + PC L  + P + +HW+ 
Sbjct: 1951 V-SPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSE 2009

Query: 606  KAILQFQKLCGLKPLVGVVDEY 627
            +A + F+       LV    EY
Sbjct: 2010 EAKIFFRDFLSKPDLVFQFREY 2031



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 11/150 (7%)

Query: 465  PPLDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPEC 524
            P +  ++ +  +V  I +P+ F+I++   +S  +    + +     + +L   + V P  
Sbjct: 1435 PQIYLNAKVKGYVSNISNPANFHIQLAENESVII---RLADALNATARRLRERKSVKPLV 1491

Query: 525  FIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL 584
                G L     S D   YR +I ++L     EV + D+GN  IV  S +  L+  +  +
Sbjct: 1492 ----GDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTV 1547

Query: 585  PAQAIPCSLA---WVRPVEEHWTSKAILQF 611
            P   I   L+   W  P +E W  K +  F
Sbjct: 1548 PQLGIHAFLSGVKWNEP-DEIWDDKTVDYF 1576



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 40/193 (20%), Positives = 80/193 (41%), Gaps = 20/193 (10%)

Query: 406  WNCPSKKQKEPQQKICKKPNLV---VKPLQLQVETNKSELNLAMANHDIPPDAVPNKKLC 462
            W   SK QK   Q     P ++   V+P   +++  KS  +    N +     +P ++  
Sbjct: 1615 WKACSKLQKSALQM----PQVLSQKVRPGDNEMKKGKSNESEGSMNSNQQLFKIPLEEF- 1669

Query: 463  RLPPLDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMP 522
            +L  L+ + ++ V         +FY+++    + ++L D+++ + +    +     ++  
Sbjct: 1670 KLGQLEKAEMLNVS-----KSGRFYVKLSK--NKKILSDLIVLITK----EEKKSPFLSM 1718

Query: 523  ECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYT 582
            E  I+ G  C  +      W+R  +       +V VF  D G   IV   + + L     
Sbjct: 1719 ES-IEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIR 1777

Query: 583  KLPAQAIPCSLAW 595
             +P QA+PC   W
Sbjct: 1778 NIPRQAVPCKWIW 1790


>gi|169164192 PREDICTED: similar to tudor domain containing 1 [Homo
           sapiens]
          Length = 2080

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 53/175 (30%), Positives = 95/175 (54%), Gaps = 14/175 (8%)

Query: 476 FVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVR 535
           F+ Y+++PS F++R  + D     +++M  + + Y +   +D  ++ +   +PG  CC R
Sbjct: 633 FIAYVLNPSNFWVR--TNDHRNEFQEIMKNINKFY-DLCENDEMILRKP--EPGLFCCAR 687

Query: 536 ISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAW 595
            S+D+ +YR +I  +    ++ V++ D+GN   +    ++ L   + +LPA A+ CSLA 
Sbjct: 688 YSKDRRFYRAVITEI-NGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAH 746

Query: 596 VRPVEEHWTSKAILQFQKLCGLKPLVGVV-----DEYVDGILNIFLCDTSSNEDV 645
           + PVE+ WT  AI  F+KL   K ++  V     D+Y    +NI   + S N DV
Sbjct: 747 IFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYT---VNIQSVEASENIDV 798



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 56/221 (25%), Positives = 95/221 (42%), Gaps = 29/221 (13%)

Query: 475  VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCV 534
            V++ +I SP +FY ++  R++ +L    MIE +   S  L +     P+       +C  
Sbjct: 1115 VYISHIYSPQKFYCQL-GRNNKDL---EMIETKITESVNLQN----FPKYDSNKMRVCIS 1166

Query: 535  RISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL---PAQAIPC 591
            +  ED   YR +        E +V++ DFGN  +V ++ LR +   + +L   P QAI C
Sbjct: 1167 KYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKC 1226

Query: 592  SLAWVRPVE-----EHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVY 646
             L+ +R V+       W     L      G      ++ +  DG L I L D S     Y
Sbjct: 1227 FLSDLRDVDIPAEISSWFKDNFL------GRSLKAIILSQESDGQLGIELYDGSQ----Y 1276

Query: 647  FHHVLRTEGHAI---VCRENISSKGFSELNPLALYTTSSGG 684
             +  ++   HA     C +    +  +++N    +TTS  G
Sbjct: 1277 INEKIKVLLHAYGKRHCDQACCMEKSNKINENKRFTTSLKG 1317



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 7/129 (5%)

Query: 465 PPLDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPEC 524
           P L   S   V V   +SPS+FY ++        LE++   M   Y       +   P C
Sbjct: 381 PSLSVGSTESVKVSSALSPSKFYCQLIKWTPE--LENLTAHMTLHYDTVC---QETSPTC 435

Query: 525 FIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL 584
                 L CV    +  W+R I+ ++L   +V++++ D+G+   +    ++ LK  +  +
Sbjct: 436 --DNFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILV 493

Query: 585 PAQAIPCSL 593
           P  + PCSL
Sbjct: 494 PLFSFPCSL 502



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 11/142 (7%)

Query: 494  DSSELLEDMMIEMRRCYSNQLVSDR----YVMPECFIQPGHLCCVRISEDKWWYRVIIHR 549
            D S  LED    M+  Y   L+SD       +P+ FI PG  C  +   +  W RV I  
Sbjct: 1893 DFSIQLEDFFDIMK--YLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISE 1950

Query: 550  VLEKQEVEVFYPDFGNIGIVQKSSLRFLKCC---YTKLPAQAIPCSLAWVRPVE-EHWTS 605
            V   Q + +   D+G    ++ S +  LK        LP  + PC L  + P + +HW+ 
Sbjct: 1951 V-SPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSE 2009

Query: 606  KAILQFQKLCGLKPLVGVVDEY 627
            +A + F+       LV    EY
Sbjct: 2010 EAKIFFRDFLSKPDLVFQFREY 2031



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 11/150 (7%)

Query: 465  PPLDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPEC 524
            P +  ++ +  +V  I +P+ F+I++   +S  +    + +     + +L   + V P  
Sbjct: 1435 PQIYLNAKVKGYVSNISNPANFHIQLAENESVII---RLADALNATARRLRERKSVKPLV 1491

Query: 525  FIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL 584
                G L     S D   YR +I ++L     EV + D+GN  IV  S +  L+  +  +
Sbjct: 1492 ----GDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTV 1547

Query: 585  PAQAIPCSLA---WVRPVEEHWTSKAILQF 611
            P   I   L+   W  P +E W  K +  F
Sbjct: 1548 PQLGIHAFLSGVKWNEP-DEIWDDKTVDYF 1576



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 40/193 (20%), Positives = 80/193 (41%), Gaps = 20/193 (10%)

Query: 406  WNCPSKKQKEPQQKICKKPNLV---VKPLQLQVETNKSELNLAMANHDIPPDAVPNKKLC 462
            W   SK QK   Q     P ++   V+P   +++  KS  +    N +     +P ++  
Sbjct: 1615 WKACSKLQKSALQM----PQVLSQKVRPGDNEMKKGKSNESEGSMNSNQQLFKIPLEEF- 1669

Query: 463  RLPPLDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMP 522
            +L  L+ + ++ V         +FY+++    + ++L D+++ + +    +     ++  
Sbjct: 1670 KLGQLEKAEMLNVS-----KSGRFYVKLSK--NKKILSDLIVLITK----EEKKSPFLSM 1718

Query: 523  ECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYT 582
            E  I+ G  C  +      W+R  +       +V VF  D G   IV   + + L     
Sbjct: 1719 ES-IEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIR 1777

Query: 583  KLPAQAIPCSLAW 595
             +P QA+PC   W
Sbjct: 1778 NIPRQAVPCKWIW 1790


>gi|169163210 PREDICTED: similar to tudor domain containing 1 [Homo
           sapiens]
          Length = 2080

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 53/175 (30%), Positives = 95/175 (54%), Gaps = 14/175 (8%)

Query: 476 FVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVR 535
           F+ Y+++PS F++R  + D     +++M  + + Y +   +D  ++ +   +PG  CC R
Sbjct: 633 FIAYVLNPSNFWVR--TNDHRNEFQEIMKNINKFY-DLCENDEMILRKP--EPGLFCCAR 687

Query: 536 ISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAW 595
            S+D+ +YR +I  +    ++ V++ D+GN   +    ++ L   + +LPA A+ CSLA 
Sbjct: 688 YSKDRRFYRAVITEI-NGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAH 746

Query: 596 VRPVEEHWTSKAILQFQKLCGLKPLVGVV-----DEYVDGILNIFLCDTSSNEDV 645
           + PVE+ WT  AI  F+KL   K ++  V     D+Y    +NI   + S N DV
Sbjct: 747 IFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYT---VNIQSVEASENIDV 798



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 56/221 (25%), Positives = 95/221 (42%), Gaps = 29/221 (13%)

Query: 475  VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCV 534
            V++ +I SP +FY ++  R++ +L    MIE +   S  L +     P+       +C  
Sbjct: 1115 VYISHIYSPQKFYCQL-GRNNKDL---EMIETKITESVNLQN----FPKYDSNKMRVCIS 1166

Query: 535  RISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL---PAQAIPC 591
            +  ED   YR +        E +V++ DFGN  +V ++ LR +   + +L   P QAI C
Sbjct: 1167 KYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIKC 1226

Query: 592  SLAWVRPVE-----EHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVY 646
             L+ +R V+       W     L      G      ++ +  DG L I L D S     Y
Sbjct: 1227 FLSDLRDVDIPAEISSWFKDNFL------GRSLKAIILSQESDGQLGIELYDGSQ----Y 1276

Query: 647  FHHVLRTEGHAI---VCRENISSKGFSELNPLALYTTSSGG 684
             +  ++   HA     C +    +  +++N    +TTS  G
Sbjct: 1277 INEKIKVLLHAYGKRHCDQACCMEKSNKINENKRFTTSLKG 1317



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 7/129 (5%)

Query: 465 PPLDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPEC 524
           P L   S   V V   +SPS+FY ++        LE++   M   Y       +   P C
Sbjct: 381 PSLSVGSTESVKVSSALSPSKFYCQLIKWTPE--LENLTAHMTLHYDTVC---QETSPTC 435

Query: 525 FIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL 584
                 L CV    +  W+R I+ ++L   +V++++ D+G+   +    ++ LK  +  +
Sbjct: 436 --DNFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILV 493

Query: 585 PAQAIPCSL 593
           P  + PCSL
Sbjct: 494 PLFSFPCSL 502



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 11/142 (7%)

Query: 494  DSSELLEDMMIEMRRCYSNQLVSDR----YVMPECFIQPGHLCCVRISEDKWWYRVIIHR 549
            D S  LED    M+  Y   L+SD       +P+ FI PG  C  +   +  W RV I  
Sbjct: 1893 DFSIQLEDFFDIMK--YLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQWNRVEISE 1950

Query: 550  VLEKQEVEVFYPDFGNIGIVQKSSLRFLKCC---YTKLPAQAIPCSLAWVRPVE-EHWTS 605
            V   Q + +   D+G    ++ S +  LK        LP  + PC L  + P + +HW+ 
Sbjct: 1951 V-SPQSLCLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAKGKHWSE 2009

Query: 606  KAILQFQKLCGLKPLVGVVDEY 627
            +A + F+       LV    EY
Sbjct: 2010 EAKIFFRDFLSKPDLVFQFREY 2031



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 11/150 (7%)

Query: 465  PPLDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPEC 524
            P +  ++ +  +V  I +P+ F+I++   +S  +    + +     + +L   + V P  
Sbjct: 1435 PQIYLNAKVKGYVSNISNPANFHIQLAENESVII---RLADALNATARRLRERKSVKPLV 1491

Query: 525  FIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL 584
                G L     S D   YR +I ++L     EV + D+GN  IV  S +  L+  +  +
Sbjct: 1492 ----GDLVVAEYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTV 1547

Query: 585  PAQAIPCSLA---WVRPVEEHWTSKAILQF 611
            P   I   L+   W  P +E W  K +  F
Sbjct: 1548 PQLGIHAFLSGVKWNEP-DEIWDDKTVDYF 1576



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 40/193 (20%), Positives = 80/193 (41%), Gaps = 20/193 (10%)

Query: 406  WNCPSKKQKEPQQKICKKPNLV---VKPLQLQVETNKSELNLAMANHDIPPDAVPNKKLC 462
            W   SK QK   Q     P ++   V+P   +++  KS  +    N +     +P ++  
Sbjct: 1615 WKACSKLQKSALQM----PQVLSQKVRPGDNEMKKGKSNESEGSMNSNQQLFKIPLEEF- 1669

Query: 463  RLPPLDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMP 522
            +L  L+ + ++ V         +FY+++    + ++L D+++ + +    +     ++  
Sbjct: 1670 KLGQLEKAEMLNVS-----KSGRFYVKLSK--NKKILSDLIVLITK----EEKKSPFLSM 1718

Query: 523  ECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYT 582
            E  I+ G  C  +      W+R  +       +V VF  D G   IV   + + L     
Sbjct: 1719 ES-IEKGLECLAKSKNTLKWHRSKVEEKYVDDKVLVFLVDCGIYEIVPVCNTKLLSNEIR 1777

Query: 583  KLPAQAIPCSLAW 595
             +P QA+PC   W
Sbjct: 1778 NIPRQAVPCKWIW 1790


>gi|58197558 tudor domain containing 6 [Homo sapiens]
          Length = 2096

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 61/210 (29%), Positives = 101/210 (48%), Gaps = 11/210 (5%)

Query: 477 VEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRI 536
           VE++ +PS+F+IR+  R  +     +M  M   YS+    D  V+     +P  LCCV+ 
Sbjct: 493 VEFVKNPSEFWIRL--RKHNVTFSKLMRRMCGFYSSASKLDGVVLKP---EPDDLCCVKW 547

Query: 537 SEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWV 596
            E+ + YR I+ + L+ + V+VF  D GN   V    +R L   + +LP  A+ C+LA +
Sbjct: 548 KENGY-YRAIVTK-LDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADI 605

Query: 597 RPVEEHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGH 656
            P+ + W+ +A+  F+K    K LV  + +  D    I + D S   +     V+   G+
Sbjct: 606 WPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDESRTGEENISKVIAQAGY 665

Query: 657 A----IVCRENISSKGFSELNPLALYTTSS 682
           A       +ENI     S  +    +TT S
Sbjct: 666 AKYQEFETKENILVNAHSPGHVSNHFTTES 695



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 22/168 (13%)

Query: 475  VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCV 534
            V++ +I  P  FY ++ +R+++      ++E   C   QL      +    + PG LC  
Sbjct: 990  VYITHIDDPWTFYCQL-ARNAN------ILEQLSCSITQLSKVLLNLKTSPLNPGTLCLA 1042

Query: 535  RISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKC---CYTKLPAQAIPC 591
            + ++  W+  ++I    EK+  +VF+ DFGNI +V    L  +         LP QA+ C
Sbjct: 1043 KYTDGNWYRGIVI----EKEPKKVFFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAVRC 1098

Query: 592  SLAWVRPVEEHWTSKAILQFQKLC---GLKPLVGVVDEYVDGILNIFL 636
            SL+    + +H   + ++ FQ+      LK LV   D   DG L I L
Sbjct: 1099 SLS---DIPDHIPEEVVVWFQETILDKSLKALVVAKDP--DGTLIIEL 1141



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 36/141 (25%), Positives = 62/141 (43%), Gaps = 16/141 (11%)

Query: 475  VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQP----GH 530
            V+V +I   S FY+        +L+ED   E    + ++ ++     PE ++ P    G 
Sbjct: 1309 VYVSHINDLSDFYV--------QLIED---EAEISHLSERLNSVKTRPEYYVGPPLQRGD 1357

Query: 531  LCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIP 590
            + C    ED  WYR +I        + V + D+GN+ +V  + +  L      LP   I 
Sbjct: 1358 MICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIH 1417

Query: 591  CSLAWVRPVEEHWTSKAILQF 611
            CSL     V ++  SK ++ +
Sbjct: 1418 CSLQGFE-VPDNKNSKKMMHY 1437



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 7/124 (5%)

Query: 472  LIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHL 531
            +I  +   I  P  F+ +    +  + LE   +E++     Q+   R  +P  +I  G  
Sbjct: 1520 MIRAYATVIDGPEYFWCQFADTEKLQCLE---VEVQTA-GEQVADRRNCIPCPYI--GDP 1573

Query: 532  CCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNI-GIVQKSSLRFLKCCYTKLPAQAIP 590
            C VR  ED  +YR +I  + E   V V   DFGNI   V   +L  +      +P QA P
Sbjct: 1574 CIVRYREDGHYYRALITNICEDYLVSVRLVDFGNIEDCVDPKALWAIPSELLSVPMQAFP 1633

Query: 591  CSLA 594
            C L+
Sbjct: 1634 CCLS 1637



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 36/166 (21%), Positives = 65/166 (39%), Gaps = 6/166 (3%)

Query: 533 CVRISEDKWWYRVIIHRVLEKQE-VEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPC 591
           C     D  WYR ++      Q   +V + D+G   +V  SSLR+L   Y ++P    PC
Sbjct: 317 CASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPC 376

Query: 592 SLAWVRPVEEHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVL 651
           +L  +      W+   +   + L  L   V    E+     +++       + +  + V 
Sbjct: 377 ALYGLWDGGRGWSRSQVGDLKTLI-LGKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRVF 435

Query: 652 RTEGHAIVCRENISSKGFSELNPLALYTTSSGGPEDIVLTELGYPS 697
             +   +  R  + S+   E  P    T+ S  P + V  E+  P+
Sbjct: 436 GVQSCCLADRV-LQSQATEEEEP---ETSQSQSPAEEVDEEISLPA 477



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 35/151 (23%), Positives = 67/151 (44%), Gaps = 14/151 (9%)

Query: 467 LDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFI 526
           L+  S + V V Y+ +P  F+ ++ +R+   L   M      C +      R  +     
Sbjct: 768 LEVGSTVEVRVSYVENPGYFWCQL-TRNIQGLKTLMSDIQYYCKNTAAPHQRNTLA---- 822

Query: 527 QPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPA 586
                C  + + ++ W R +I  +   + V V + D+G+  +V   ++  +   + K+ A
Sbjct: 823 -----CLAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKA 877

Query: 587 QAIPCSL-AWVRPVEEH---WTSKAILQFQK 613
           QA  CSL   ++PV ++   W  KAI  F +
Sbjct: 878 QAFRCSLYNLIQPVGQNPFVWDVKAIQAFNE 908


>gi|94421471 ring finger protein 17 [Homo sapiens]
          Length = 1623

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 46/170 (27%), Positives = 83/170 (48%), Gaps = 10/170 (5%)

Query: 473 IGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLC 532
           + V V +I SP  FY+++   +  ++L  ++  +   Y ++   +  ++  C +Q     
Sbjct: 680 VSVTVCHINSPGDFYLQLI--EGLDILF-LLKTIEEFYKSEDGENLEIL--CPVQDQ--A 732

Query: 533 CVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCS 592
           CV   ED  WYR  +  +   QEVEV Y DFGN   +    +R +K  +   P +AI C 
Sbjct: 733 CVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCK 792

Query: 593 LAWVRPVEE--HWTSKAILQFQKLCGLKPLV-GVVDEYVDGILNIFLCDT 639
           LA++ P +    W+ +A  +F++    K +   V+    D +L + L D+
Sbjct: 793 LAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDS 842



 Score = 38.1 bits (87), Expect = 0.041
 Identities = 42/172 (24%), Positives = 71/172 (41%), Gaps = 22/172 (12%)

Query: 450  DIPPDAVPNKKLCRLPPLDTSSL------------IGVFVEYIISPSQFYIRIYSRDSSE 497
            D  P+ + + ++  L P+   SL            + V +  +ISP + Y++    ++  
Sbjct: 883  DPSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTEN-- 940

Query: 498  LLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVE 557
            LL  +  +M   Y N         P  +    H C V+I +   W R  I R++    VE
Sbjct: 941  LLNSLEEKMIAAYENSKWE-----PVKWENDMH-CAVKIQDKNQWRRGQIIRMVTDTLVE 994

Query: 558  VFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPV--EEHWTSKA 607
            V   D G   +V    LR L+     +   ++ CSL  +RP    + WT+ A
Sbjct: 995  VLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATA 1046



 Score = 33.9 bits (76), Expect = 0.77
 Identities = 30/90 (33%), Positives = 38/90 (42%), Gaps = 3/90 (3%)

Query: 525  FIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKL 584
            F + G  C VR S D  WYR  +  V+    V V Y D G    + +  L +    Y  +
Sbjct: 1228 FWKKGEACAVRGS-DTLWYRGKVMEVVGGA-VRVQYLDHGFTEKIPQCHL-YPILLYPDI 1284

Query: 585  PAQAIPCSLAWVRPVEEHWTSKAILQFQKL 614
            P   IPC L    PV   W   AI   Q+L
Sbjct: 1285 PQFCIPCQLHNTTPVGNVWQPDAIEVLQQL 1314


>gi|166851804 tudor domain containing 9 [Homo sapiens]
          Length = 1382

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 51/212 (24%), Positives = 88/212 (41%), Gaps = 16/212 (7%)

Query: 469  TSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQP 528
            T  L+ + V  ++    F+      ++SE+L+ +  E+     NQL     V       P
Sbjct: 896  TDLLLTIDVTEVVEVGHFWGYRIDENNSEILKKLTAEI-----NQLT---LVPLPTHPHP 947

Query: 529  GHLCCVRISE-DKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQ 587
              +C    ++ DK  Y       +     EVF+ D+GN   V    L  + C + +LP Q
Sbjct: 948  DLVCLAPFADFDKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQ 1007

Query: 588  AIPCSLAWVRP------VEEHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSS 641
            A+   +  +RP        +HW+  A   F  L     L+  V   V  +L++ +   S 
Sbjct: 1008 ALEFKICKMRPSAKSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSG 1067

Query: 642  NED-VYFHHVLRTEGHAIVCRENISSKGFSEL 672
             +D +    VL  +G+A +  E+  SK   E+
Sbjct: 1068 VQDAINIRDVLIQQGYAELTEESYESKQSHEV 1099


>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
          Length = 903

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 53/220 (24%), Positives = 92/220 (41%), Gaps = 27/220 (12%)

Query: 417 QQKICKKPNLVVKPLQLQVETNKSELNLAMANHDIPPDAVPNKKLCRLPPLDTSSLI--- 473
           Q  + K  NL+ K  +        ELNL   N   PP  +P+  L  LP   TS L+   
Sbjct: 661 QHHVDKALNLIGKKFK--------ELNLT--NIYAPP--LPSLALPSLPM--TSWLMLPD 706

Query: 474 GVFVEYII----SPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPG 529
           G+ VE I+    +    +++ ++  +   L  +  +M  CYS   +       E  +   
Sbjct: 707 GITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITV--- 763

Query: 530 HLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAI 589
            +C    ++  WW   ++    E  EVE+ Y D+G    V+   LR ++  +  LP Q  
Sbjct: 764 -ICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGA 822

Query: 590 PCSLAWVRPV--EEHWTSKAILQFQKLCGLKPLVGVVDEY 627
              L  V P+  ++ ++ +A     ++ G   L+  V  Y
Sbjct: 823 EVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSY 862


>gi|77404397 staphylococcal nuclease domain containing 1 [Homo
           sapiens]
          Length = 910

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 9/125 (7%)

Query: 475 VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCV 534
           VFV  I     FY++    ++   LE +M  MR    N + S   V      + G  C  
Sbjct: 685 VFVTEITDDLHFYVQ--DVETGTQLEKLMENMR----NDIASHPPVEGSYAPRRGEFCIA 738

Query: 535 RISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTK--LPAQAIPCS 592
           +  + +W YR  + +V    ++ VFY D+GN  ++  + L  L   ++   LPAQA   +
Sbjct: 739 KFVDGEW-YRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYA 797

Query: 593 LAWVR 597
            A+++
Sbjct: 798 FAFIQ 802


>gi|85797660 limkain b1 [Homo sapiens]
          Length = 1742

 Score = 38.5 bits (88), Expect = 0.031
 Identities = 62/298 (20%), Positives = 107/298 (35%), Gaps = 65/298 (21%)

Query: 138  ELKDLLALSPVLLSDFEK---AFAKRFGRSFQYMQYGFLSMFEVLNAASDVISVEQTRAG 194
            ++ DLL   P     F K   ++   FGR  +   YGF  + E+  A  D + V +    
Sbjct: 1266 DVVDLLRHQPHFRMPFNKFIPSYHHHFGRQCKLAYYGFTKLLELFEAIPDTLQVLECGEE 1325

Query: 195  SLLMLKK------------SVTEEKPRGC--------PAGKIFTQPFRMKQGSYSTGFPV 234
             +L L +             +   +   C           K F   FR++    S+   +
Sbjct: 1326 KILTLTEVERFKALAAQFVKLLRSQKDNCLMMTDLLTEYAKTFGYTFRLQDYDVSSISAL 1385

Query: 235  A-KPCFSQPTSNMEPPKQI-------------------MSMEKTSKLNVVETSR---LNH 271
              K C     +++E  +QI                   MS E T+ L+V E  R     H
Sbjct: 1386 TQKLCHVVKVADIESGRQIQLINRKSLRSLTAQLLVLLMSWEGTTHLSVEELKRHYESTH 1445

Query: 272  TEKLNQLENTFKSV---------IAQIGPGGTISSELKHKIKFVVSKFPEGL-------- 314
               LN  E  F ++         + ++     +   +K    ++ +K    L        
Sbjct: 1446 NTPLNPCEYGFMTLTELLKSLPYLVEVFTNDKMEECVKLTSLYLFAKNVRSLLHTYHYQQ 1505

Query: 315  -FISKLLGEYEVIFKEQLSPKKLGFLNVTELVGALSDILHVEFRKGHQDLLVFDADKK 371
             F+ +    Y     E L PK  G  +V EL+GA+  ++ ++   GH+ ++V   D K
Sbjct: 1506 IFLHEFSMAYTKYVGETLQPKTYGHSSVEELLGAIPQVVWIK-GHGHKRIVVLKNDMK 1562


>gi|161016765 tudor domain containing 12 [Homo sapiens]
          Length = 395

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 18/107 (16%)

Query: 526 IQPGHLCCVRISEDKWWYRVIIHRVLEKQE---VEVFYPDFGNIGIVQKSSLRFLKCCYT 582
           ++ G +C V   E K W R I+  +    +    E F  DF     V+  ++R +   + 
Sbjct: 57  LEEGQVCVVYCEELKCWCRAIVKSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFM 116

Query: 583 KLPAQAIPCSLAWVRPVEEH---------------WTSKAILQFQKL 614
           +LP +A   SL   +PV  H               W + AI  FQ L
Sbjct: 117 QLPYRAKKFSLYCTKPVTLHIDFCRDSTDIVPAKKWDNAAIQYFQNL 163


>gi|94421473 paternally expressed 10 isoform RF1 [Homo sapiens]
          Length = 325

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 19/159 (11%)

Query: 817 AQEKNTGTNRTQKQLDINGSSDSSTLPKLEEFCTSLTQSEQSADGSQSEPNNSQTQPKQI 876
           ++E N    +  KQ + N +  S      EE   + T  EQ     + E ++ + +    
Sbjct: 10  SEEINNLREKVMKQSEENNNLQSQVQKLTEE---NTTLREQVEPTPEDEDDDIELRGAAA 66

Query: 877 QLSTAAPCSTTAVDDSAEKPSGSVESSPEILKNEDFSSSRAITLYKDKRQESVDQLSLIL 936
             +   P      +D  EK  G+    P++L    F +   I + K  R  SVD++ +  
Sbjct: 67  AAAPPPPIEEECPEDLPEKFDGN----PDMLA--PFMAQCQIFMEKSTRDFSVDRVRV-- 118

Query: 937 SYECQISQKLYIPRSTATAALGAAARLATSRSLLHWYPS 975
              C ++  +     T  AA  A+A+L  S  L+H YP+
Sbjct: 119 ---CFVTSMM-----TGRAARWASAKLERSHYLMHNYPA 149


>gi|94421475 paternally expressed 10 isoform RF1/2 [Homo sapiens]
          Length = 708

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 19/159 (11%)

Query: 817 AQEKNTGTNRTQKQLDINGSSDSSTLPKLEEFCTSLTQSEQSADGSQSEPNNSQTQPKQI 876
           ++E N    +  KQ + N +  S      EE   + T  EQ     + E ++ + +    
Sbjct: 10  SEEINNLREKVMKQSEENNNLQSQVQKLTEE---NTTLREQVEPTPEDEDDDIELRGAAA 66

Query: 877 QLSTAAPCSTTAVDDSAEKPSGSVESSPEILKNEDFSSSRAITLYKDKRQESVDQLSLIL 936
             +   P      +D  EK  G+    P++L    F +   I + K  R  SVD++ +  
Sbjct: 67  AAAPPPPIEEECPEDLPEKFDGN----PDMLA--PFMAQCQIFMEKSTRDFSVDRVRV-- 118

Query: 937 SYECQISQKLYIPRSTATAALGAAARLATSRSLLHWYPS 975
              C ++  +     T  AA  A+A+L  S  L+H YP+
Sbjct: 119 ---CFVTSMM-----TGRAARWASAKLERSHYLMHNYPA 149


>gi|117606360 ADP-ribosylation factor guanine nucleotide factor 6
           isoform a [Homo sapiens]
          Length = 1047

 Score = 33.1 bits (74), Expect = 1.3
 Identities = 36/163 (22%), Positives = 59/163 (36%), Gaps = 20/163 (12%)

Query: 706 RKISPQSKESELRILDEIPTGMPCLESVTIGDDIWDENWLPLQAKMGKGGDAASHLFTAS 765
           R  SP SKES  ++   + +      S ++ +++WDE+W     + G      S +    
Sbjct: 328 RTASPDSKESS-KVPRHLISSAGLCNSSSLTENVWDESWKAPSERPGTSSGTFSPVRLDE 386

Query: 766 LGGKNQYSSCKEMPQKDWCFSTPKDTWDDSWQPSGLVNGTKVEVHKPEVLGAQEKNTGTN 825
            G    +        K     TPK   D            ++   +  V G  E   G  
Sbjct: 387 SGEDEVFL----QENKQHLEKTPKPERDRE----------RISEQEEHVKGEDEDILGPG 432

Query: 826 RTQKQLDINGSSDSSTLPKLEEFCTSLTQSEQSADGSQSEPNN 868
            T+   D+  S   + L       TSL  S +S +   SEP++
Sbjct: 433 YTEDSTDVYSSQFETILDN-----TSLYYSAESLETLYSEPDS 470


>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
          Length = 1256

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 8/123 (6%)

Query: 794 DSWQPSGLVNGTKVEVHKPEVLGAQEKNTGTNRTQKQLDINGSSDSSTLPKLEEFCTSLT 853
           +SW+     N +  E     VL   E++       K L+ + SSDSS   K++     L 
Sbjct: 802 ESWR-----NPSSSEEEPSPVLKTLERSAARKMPSKSLE-DISSDSSNQAKVDNQPEELV 855

Query: 854 QSEQSADGSQSEPNNSQTQPKQI-QLSTAAPCSTTAVDDSAEKPSGSVESSPEILKNEDF 912
           +S +      ++P+N  + P ++ ++S + P       D  E  + S ESS ++ +++  
Sbjct: 856 RSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTAS-ESSYQLSRHKKS 914

Query: 913 SSS 915
            SS
Sbjct: 915 PSS 917


>gi|82830424 gon-4-like isoform a [Homo sapiens]
          Length = 2240

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 41/147 (27%), Positives = 67/147 (45%), Gaps = 29/147 (19%)

Query: 786  STPKDTWDDSWQPSGLVNGTKV------EVHKPEVLGAQEKNTGTNRTQKQLD-INGSSD 838
            S+P    +DS    G   GT V      E + PE    +E+    + TQ + D ++ +S+
Sbjct: 1425 SSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPE---EEEEEDFDDLTQDEEDEMSSASE 1481

Query: 839  SSTL--PKLEEFCTSLT----QSEQSADGSQSEPNNSQ--TQPKQIQ---------LSTA 881
             S L  P+L+E    LT    +   S +G   E N+ +  ++P++ +         L   
Sbjct: 1482 ESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKE 1541

Query: 882  APCSTTAVDDSAEKPS--GSVESSPEI 906
               +  AV DSAEKP    S E++PE+
Sbjct: 1542 DEMTDEAVGDSAEKPPTFASPETAPEV 1568


>gi|170784859 serine/threonine kinase 31 isoform b [Homo sapiens]
          Length = 996

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 13/38 (34%), Positives = 24/38 (63%)

Query: 537 SEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSL 574
           SED+ WYR  + +++  ++  V Y D+GN  I+ +S +
Sbjct: 67  SEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDI 104


>gi|14602443 serine/threonine kinase 31 isoform a [Homo sapiens]
          Length = 1019

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 13/38 (34%), Positives = 24/38 (63%)

Query: 537 SEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSL 574
           SED+ WYR  + +++  ++  V Y D+GN  I+ +S +
Sbjct: 90  SEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDI 127


>gi|170784856 serine/threonine kinase 31 isoform b [Homo sapiens]
          Length = 996

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 13/38 (34%), Positives = 24/38 (63%)

Query: 537 SEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSL 574
           SED+ WYR  + +++  ++  V Y D+GN  I+ +S +
Sbjct: 67  SEDQCWYRCKVLKIISVEKCLVRYIDYGNTEILNRSDI 104


>gi|45827771 autoantigen RCD8 [Homo sapiens]
          Length = 1401

 Score = 32.7 bits (73), Expect = 1.7
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 6/96 (6%)

Query: 836 SSDSSTLPKL---EEFCT---SLTQSEQSADGSQSEPNNSQTQPKQIQLSTAAPCSTTAV 889
           S  S T PKL   + F T   SL Q   S   S S  ++S +       + +A  ST+AV
Sbjct: 583 SLSSETKPKLMTPDAFMTPSASLQQITASPSSSSSGSSSSSSSSSSSLTAVSAMSSTSAV 642

Query: 890 DDSAEKPSGSVESSPEILKNEDFSSSRAITLYKDKR 925
           D S  +P   +  SP++  +   + S + +L    R
Sbjct: 643 DPSLTRPPEELTLSPKLQLDGSLTMSSSGSLQASPR 678


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 32.3 bits (72), Expect = 2.2
 Identities = 27/123 (21%), Positives = 46/123 (37%), Gaps = 12/123 (9%)

Query: 800  GLVNGTKVEVHKPEVLGAQEKNTGTNRTQKQLD-----------INGSSDSSTLPKLEEF 848
            GLVN      H  ++      NT  N   K L+           + GS  +S+  K E+ 
Sbjct: 2220 GLVNDLARVPHSLDLSSPNMANT-VNAALKPLETLSRIVNQPSSLFGSKSASSKNKSEQD 2278

Query: 849  CTSLTQSEQSADGSQSEPNNSQTQPKQIQLSTAAPCSTTAVDDSAEKPSGSVESSPEILK 908
                +Q   S      EP  ++ Q +   ++         +D  AE  S  +   PE+L 
Sbjct: 2279 AQGASQDSSSNQQDPGEPGEAEVQEEDHDVTQTEVADGDIMDGEAETDSVVIAGQPEVLS 2338

Query: 909  NED 911
            +++
Sbjct: 2339 SQE 2341


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 32.3 bits (72), Expect = 2.2
 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 26/110 (23%)

Query: 847 EFCTSLTQSEQSADGSQSEPNNSQTQPKQIQLSTAAPCSTTAVD------DSAEKPSGSV 900
           E  TSL Q E SA  + +E +N++T  +  +   + P + T+ D      D A+K   + 
Sbjct: 206 ETITSLNQ-EASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTA 264

Query: 901 ESSPEIL----KNEDFSS---------------SRAITLYKDKRQESVDQ 931
           +S  E L    K+E+FS                +  I L KD +QES +Q
Sbjct: 265 DSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQ 314


>gi|55769554 protein tyrosine phosphatase, receptor type, f
           polypeptide (PTPRF), interacting protein (liprin), alpha
           4 [Homo sapiens]
          Length = 701

 Score = 32.3 bits (72), Expect = 2.2
 Identities = 53/213 (24%), Positives = 78/213 (36%), Gaps = 46/213 (21%)

Query: 751 MGKGGDAASHLFT---ASLGGKNQYSSCKEMPQKDW---------------CFSTPKDTW 792
           MG   D    L T   A  G   +YS+ +E   KDW                F +  +  
Sbjct: 1   MGSAADVRFSLGTTTHAPPGVHRRYSALREESAKDWETSPLPGMLAPAAGPAFDSDPEIS 60

Query: 793 D-DSWQPSGLVNGTKVEVHKPEVLGAQEKNTGTNRTQKQLD--------INGSSDSSTLP 843
           D D  +P GLV     +V  P   G  +  T     Q+QLD        I    +S+ L 
Sbjct: 61  DVDEDEPGGLVGSA--DVVSPS--GHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTEL- 115

Query: 844 KLEEFCTSLTQSEQSADGSQSEPNNSQTQPKQIQLSTAAPCSTTAVDDSAEKPSGSVESS 903
           + EE  T +T     A              KQ++   + P S TA+  ++  P  S  S+
Sbjct: 116 RAEEIETRVTSGSMEA-----------LNLKQLRKRGSIPTSLTALSLASASPPLSGRST 164

Query: 904 PEILKN---EDFSSSRAITLYKDKRQESVDQLS 933
           P++      +D      +TL  D R+     LS
Sbjct: 165 PKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLS 197


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 32.0 bits (71), Expect = 2.9
 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 13/115 (11%)

Query: 352 LHVEFRKGHQDL---------LVFDADKKPLPPVQSDKKIEAKACVSSPPRNS--LSTAA 400
           L  E   GHQ L         +  +A +     V+  + +EAK+  +SP      L+   
Sbjct: 700 LDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPP 759

Query: 401 VKETVWN--CPSKKQKEPQQKICKKPNLVVKPLQLQVETNKSELNLAMANHDIPP 453
           V        CP   +  PQ K C + +L+V P ++ V+ +  +   +++    PP
Sbjct: 760 VDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPP 814


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,167,989
Number of Sequences: 37866
Number of extensions: 1768394
Number of successful extensions: 5468
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 5327
Number of HSP's gapped (non-prelim): 188
length of query: 981
length of database: 18,247,518
effective HSP length: 112
effective length of query: 869
effective length of database: 14,006,526
effective search space: 12171671094
effective search space used: 12171671094
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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