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Search of human proteins with 40254982
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40254982 hypothetical protein LOC83641 [Homo sapiens]
(306 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40254982 hypothetical protein LOC83641 [Homo sapiens] 612 e-175
gi|115583665 downregulated in renal cell carcinoma [Homo sapiens] 138 7e-33
gi|6005924 downregulated in renal cell carcinoma [Homo sapiens] 138 7e-33
gi|221139761 zinc finger protein 853 [Homo sapiens] 50 3e-06
gi|148746195 trichohyalin [Homo sapiens] 49 7e-06
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 47 2e-05
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 46 4e-05
gi|4505257 moesin [Homo sapiens] 46 5e-05
gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens] 46 5e-05
gi|21493031 A-kinase anchor protein 13 isoform 3 [Homo sapiens] 46 5e-05
gi|21493029 A-kinase anchor protein 13 isoform 2 [Homo sapiens] 46 5e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 45 6e-05
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 45 6e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 45 8e-05
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 45 1e-04
gi|4758472 G protein pathway suppressor 2 [Homo sapiens] 44 1e-04
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 43 3e-04
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 43 3e-04
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 43 3e-04
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 43 3e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 43 4e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 43 4e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 43 4e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 42 5e-04
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens] 42 5e-04
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens] 42 5e-04
gi|4506467 radixin [Homo sapiens] 42 7e-04
gi|161702986 ezrin [Homo sapiens] 42 9e-04
gi|21614499 ezrin [Homo sapiens] 42 9e-04
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 42 9e-04
>gi|40254982 hypothetical protein LOC83641 [Homo sapiens]
Length = 306
Score = 612 bits (1579), Expect = e-175
Identities = 306/306 (100%), Positives = 306/306 (100%)
Query: 1 MSTWKARLTKRLKSPSRSMHPFPCSALLACFGNTRESASFNQSGVADTHSTVRVQPVAKA 60
MSTWKARLTKRLKSPSRSMHPFPCSALLACFGNTRESASFNQSGVADTHSTVRVQPVAKA
Sbjct: 1 MSTWKARLTKRLKSPSRSMHPFPCSALLACFGNTRESASFNQSGVADTHSTVRVQPVAKA 60
Query: 61 GRQPRHPSAEGAPEKRQDSSTHAERNGSANRNSSHRTAAQPAETPEDVPGSLDDGADCEA 120
GRQPRHPSAEGAPEKRQDSSTHAERNGSANRNSSHRTAAQPAETPEDVPGSLDDGADCEA
Sbjct: 61 GRQPRHPSAEGAPEKRQDSSTHAERNGSANRNSSHRTAAQPAETPEDVPGSLDDGADCEA 120
Query: 121 VVFHASIPRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPD 180
VVFHASIPRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPD
Sbjct: 121 VVFHASIPRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPD 180
Query: 181 YIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQV 240
YIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQV
Sbjct: 181 YIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQV 240
Query: 241 IKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEV 300
IKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEV
Sbjct: 241 IKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEV 300
Query: 301 AQAQES 306
AQAQES
Sbjct: 301 AQAQES 306
>gi|115583665 downregulated in renal cell carcinoma [Homo sapiens]
Length = 144
Score = 138 bits (347), Expect = 7e-33
Identities = 72/133 (54%), Positives = 101/133 (75%), Gaps = 6/133 (4%)
Query: 175 IMAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEK 234
+MA P+Y E NPELI+P+KL+NPVK SR+HQ+LHRELLMN +RGL +KPELQ+V+E
Sbjct: 15 LMARPEYREW-NPELIKPKKLLNPVKASRSHQELHRELLMNHRRGLGVDSKPELQRVLEH 73
Query: 235 RKRDQVIKQKEEEAQKKK--SDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGN 292
R+R+Q+IK+K+EE + K+ E ELL+RQQ+L QLE +K E+++APEF+KV+ N
Sbjct: 74 RRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEK---EEDHAPEFIKVREN 130
Query: 293 LRRTGQEVAQAQE 305
LRR ++ +E
Sbjct: 131 LRRIATLTSEERE 143
>gi|6005924 downregulated in renal cell carcinoma [Homo sapiens]
Length = 144
Score = 138 bits (347), Expect = 7e-33
Identities = 72/133 (54%), Positives = 101/133 (75%), Gaps = 6/133 (4%)
Query: 175 IMAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEK 234
+MA P+Y E NPELI+P+KL+NPVK SR+HQ+LHRELLMN +RGL +KPELQ+V+E
Sbjct: 15 LMARPEYREW-NPELIKPKKLLNPVKASRSHQELHRELLMNHRRGLGVDSKPELQRVLEH 73
Query: 235 RKRDQVIKQKEEEAQKKK--SDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGN 292
R+R+Q+IK+K+EE + K+ E ELL+RQQ+L QLE +K E+++APEF+KV+ N
Sbjct: 74 RRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEK---EEDHAPEFIKVREN 130
Query: 293 LRRTGQEVAQAQE 305
LRR ++ +E
Sbjct: 131 LRRIATLTSEERE 143
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 49.7 bits (117), Expect = 3e-06
Identities = 42/185 (22%), Positives = 93/185 (50%), Gaps = 22/185 (11%)
Query: 139 EEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLINP 198
EE R + L+L+Q P + H+ + + +D +L + Q+
Sbjct: 80 EETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQ---E 136
Query: 199 VKTSRNHQDLHREL-LMNQKRGLAPQNKPELQKVMEKRKR-------DQVIKQKEEEAQK 250
S +HQ+L EL LM+Q++ L PQ E Q++ +++++ +Q + Q++E+ Q+
Sbjct: 137 KHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQ 196
Query: 251 KKSDLEI-----------ELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQE 299
+ + ++ +LL++Q++L+Q + ++Q+ Q +Q+ ++ +G L++ +
Sbjct: 197 QVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQ 256
Query: 300 VAQAQ 304
QAQ
Sbjct: 257 QQQAQ 261
Score = 43.1 bits (100), Expect = 3e-04
Identities = 37/188 (19%), Positives = 95/188 (50%), Gaps = 19/188 (10%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQK-L 195
++E+ +++ + +L Q+ + + + L + + + ++ L+ Q+
Sbjct: 190 QQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQ 249
Query: 196 INPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKK--- 252
+ + L ++LL Q+ L Q + Q+ ++++++ Q+++Q++E+ Q+++
Sbjct: 250 LQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQP 309
Query: 253 --------SDLEIEL----LKRQQKLEQL--ELEKQK-LQEEQENAPEFVKVKGNLRRTG 297
++E+EL L +Q+LEQ ELE+Q+ L+ +QE +K++ L++
Sbjct: 310 PPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLE 369
Query: 298 QEVAQAQE 305
Q++ Q Q+
Sbjct: 370 QQLEQQQQ 377
Score = 37.4 bits (85), Expect = 0.017
Identities = 47/255 (18%), Positives = 105/255 (41%), Gaps = 25/255 (9%)
Query: 44 GVADTHSTVRVQPVAKAGRQPRHPSAEGAPEKRQDSSTHAERNGSANRNSSHRTAAQPAE 103
G A + +Q + G P S + Q+ ERN S R +
Sbjct: 19 GPATETFVLELQCLEDGGPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEI 78
Query: 104 TPEDVPGSLDDGADCEAVVFHASIPRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPE-- 161
E PG + + +P P+ E+ ++ LEL+Q+ D +
Sbjct: 79 AEETRPGQRE-------LQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLS 131
Query: 162 --------DIDHKDS----YLITRSIMAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLH 209
+ H++ L+ + +P +++ L + Q+ + +
Sbjct: 132 QLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQ-RLQQQQEQLQTQQAQEQQVLQQ 190
Query: 210 RELLMNQ--KRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKK-KSDLEIELLKRQQKL 266
+E L Q ++ L Q + +LQ+ ++++Q+ +Q+ ++ Q++ + ++ LL++Q +L
Sbjct: 191 QEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQL 250
Query: 267 EQLELEKQKLQEEQE 281
+Q L++Q+ Q +Q+
Sbjct: 251 QQQLLQQQQAQLQQQ 265
Score = 36.6 bits (83), Expect = 0.029
Identities = 27/138 (19%), Positives = 70/138 (50%), Gaps = 6/138 (4%)
Query: 151 EQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLHR 210
EQ T + + + + L + + E ++ +L + Q L + + +
Sbjct: 175 EQLQTQQAQEQQVLQQQEQL--QQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQ 232
Query: 211 ELLMNQKRGLAPQNKPELQKVMEKRKR----DQVIKQKEEEAQKKKSDLEIELLKRQQKL 266
E L Q++ L Q + +LQ+ + ++++ Q+++Q++ + Q++ + E L++QQ+
Sbjct: 233 EQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQ 292
Query: 267 EQLELEKQKLQEEQENAP 284
+ L+ ++++LQ++Q P
Sbjct: 293 QLLQQQQEQLQQQQLQPP 310
Score = 34.3 bits (77), Expect = 0.14
Identities = 17/48 (35%), Positives = 36/48 (75%), Gaps = 1/48 (2%)
Query: 234 KRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQE 281
+++R ++ +Q+E E Q+++ L+++L + Q+LEQ +LE+Q+ Q EQ+
Sbjct: 336 EQQRQELERQQELERQQEQRQLQLKLQEELQQLEQ-QLEQQQQQLEQQ 382
Score = 32.3 bits (72), Expect = 0.54
Identities = 22/93 (23%), Positives = 54/93 (58%), Gaps = 6/93 (6%)
Query: 188 ELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEE 247
E ++ Q+L P +++ EL+ + ++ EL++ ++ +R Q +++++E+
Sbjct: 300 EQLQQQQLQPPPLEPEEEEEVELELMP-----VDLGSEQELEQQRQELERQQELERQQEQ 354
Query: 248 AQKK-KSDLEIELLKRQQKLEQLELEKQKLQEE 279
Q + K E++ L++Q + +Q +LE+Q++Q E
Sbjct: 355 RQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLE 387
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/102 (20%), Positives = 58/102 (56%), Gaps = 4/102 (3%)
Query: 178 EPDYIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKR 237
EP+ E+ EL+ P L + + + Q+L R+ + +++ Q + +L+ E ++
Sbjct: 313 EPEEEEEVELELM-PVDLGSEQELEQQRQELERQQELERQQ---EQRQLQLKLQEELQQL 368
Query: 238 DQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEE 279
+Q ++Q++++ ++++ LE+ ++ + ++++LE +Q E
Sbjct: 369 EQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPE 410
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.5 bits (114), Expect = 7e-06
Identities = 38/176 (21%), Positives = 82/176 (46%), Gaps = 9/176 (5%)
Query: 132 IIDTPKEEEFREEPKCLELEQKMTSDSPPE------DIDHKDSYLITRSIMAEPDYIEDD 185
+ +E+E+R+ L E++ + P+ + + + L + + E E
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Query: 186 NPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKE 245
L R Q+L + R Q R ++ + + +L++ E+R+ Q+ +++E
Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356
Query: 246 EEAQKKKSDLEIELLKRQQKL---EQLELEKQKLQEEQENAPEFVKVKGNLRRTGQ 298
EE ++++ E E +R+Q+L +QL E+Q +E+Q + ++ + LRR Q
Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Score = 45.8 bits (107), Expect = 5e-05
Identities = 40/185 (21%), Positives = 88/185 (47%), Gaps = 25/185 (13%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
++EE RE+ E E++ E + + + R + E+ + +R ++ +
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRR------EQEEERREQQLRREQQL 383
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLE 256
+ R Q L RE + +++ L + + +L++ + R+ Q+ +++EEE ++K + E
Sbjct: 384 RREQQLRREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQEEERHEQKHEQE 441
Query: 257 I-------------ELLKRQQKLEQLELEKQKLQ----EEQENAPEFVKVKGNLRRTGQE 299
+ LKR+++ E+ E E++K Q +E+E ++K++ RR QE
Sbjct: 442 RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501
Query: 300 VAQAQ 304
+ Q
Sbjct: 502 RREQQ 506
Score = 45.8 bits (107), Expect = 5e-05
Identities = 41/186 (22%), Positives = 86/186 (46%), Gaps = 10/186 (5%)
Query: 124 HASIPRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIE 183
H R + +EEE RE LE E++ E + ++ L ++
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEEERR------EQQERREQQLRREQEERREQRLK 520
Query: 184 DDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQ-KVMEKRKRDQVIK 242
E Q+L + + R ++ +LL ++ Q + E + K ++ +RDQ++K
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Query: 243 QKEEEAQ---KKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQE 299
++EE Q K++ + +E +++++E+LE E+++ Q + PE + + L+ QE
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQE 640
Query: 300 VAQAQE 305
+ Q+
Sbjct: 641 ERRQQQ 646
Score = 43.1 bits (100), Expect = 3e-04
Identities = 36/171 (21%), Positives = 82/171 (47%), Gaps = 8/171 (4%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
+EEE RE+ + E++ + + + ++ L + + E R Q+L
Sbjct: 310 QEEERREQQE----ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKR---KRDQVIKQKEEEAQKKKS 253
+ R Q L RE + +++ L + + ++ + + +R+Q ++++++ ++++
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 425
Query: 254 DLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQ 304
E E + +QK EQ E +Q+L+ EQE +++K + R QE + Q
Sbjct: 426 RREQEEERHEQKHEQ-ERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Score = 42.7 bits (99), Expect = 4e-04
Identities = 40/184 (21%), Positives = 90/184 (48%), Gaps = 23/184 (12%)
Query: 137 KEEEFREEPKCLELEQKMTSDSP-PEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKL 195
+E+ + + + L+Q++ S+ + + + L+ R E+ E R ++
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE--------EEKRLEQERREQR 566
Query: 196 INPVKTSRNHQDLHRELLMNQKRGLAPQN--------KPELQKVMEKRKRDQVIKQKEEE 247
+ + R Q L RE Q+R Q + E++++ ++ +R+Q +K++E E
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 248 AQKK----KSDLEIELLKRQQKLEQLELEKQKL--QEEQENAPEFVKVKGNLRRTGQEVA 301
+++ KS+ + E ++Q + EQ E +Q+L +EE+E + +K + R QE+A
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686
Query: 302 QAQE 305
+ ++
Sbjct: 687 EEEQ 690
Score = 41.6 bits (96), Expect = 9e-04
Identities = 40/173 (23%), Positives = 85/173 (49%), Gaps = 20/173 (11%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
+E ++REE + + E+++ E+ + + + R E + ++ + +L+R +
Sbjct: 1046 RERQYREEEELQQEEEQLLG----EERETRRRQELERQYRKEEE-LQQEEEQLLREE--- 1097
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQ--KEEEAQKKKSD 254
P K R RE ++ L + + L++ EKR+R ++ +Q +EEE Q+++
Sbjct: 1098 -PEKRRRQE----RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Query: 255 LEIELLKRQQKLEQLELEKQKLQEE--QENAPEFVKVKGNLRRTGQEVAQAQE 305
L L + +K + ELE+Q +EE Q+ + ++ + RR +E +E
Sbjct: 1153 L---LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
Score = 39.7 bits (91), Expect = 0.003
Identities = 30/106 (28%), Positives = 57/106 (53%), Gaps = 5/106 (4%)
Query: 200 KTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIEL 259
K Q LHR+ Q++ L + + Q+ ++R++D+ K +EEE + + + E +
Sbjct: 1516 KFLEEEQQLHRQ--QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE--QLRQEREEQQ 1571
Query: 260 LKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
L RQ++ + LE+QK++ QE +F++ + LRR + QE
Sbjct: 1572 LSRQERDRKFRLEEQKVR-RQEQERKFMEDEQQLRRQEGQQQLRQE 1616
Score = 38.1 bits (87), Expect = 0.010
Identities = 32/170 (18%), Positives = 81/170 (47%), Gaps = 14/170 (8%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
+E ++R++ K + E+++ + P + R E Y E++ + ++L+
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEK----------RRRQEREKKYREEEELQQ-EEEQLL 1004
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQ-KEEEAQKKKSDL 255
+ R Q+ R+ +K L + + L++ EKR+ + +Q +EEE +++ +
Sbjct: 1005 REEREKRRRQEWERQY--RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
Query: 256 EIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
+ + ++ ++LE + +K +E Q+ + ++ + RR + Q +E
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
Score = 38.1 bits (87), Expect = 0.010
Identities = 40/181 (22%), Positives = 84/181 (46%), Gaps = 25/181 (13%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLIT------RSIMAEPDYIEDDNPELI 190
+E+ REEP+ +++ E++ ++ L+ R E Y E++ +
Sbjct: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ- 1148
Query: 191 RPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQK 250
++L+ R Q+L R+ + + ELQ+ E+ R++ K+++E ++
Sbjct: 1149 EEEQLLREEPEKRRRQELERQY----------REEEELQQEEEQLLREEQEKRRQERERQ 1198
Query: 251 KKSDLEIELLKRQQKL---EQLELEKQKLQEEQENAPEFVKV--KGNLRRTGQEVAQAQE 305
+ + E++ KR+Q+ +Q K + + E+ENA KV KG R ++ Q ++
Sbjct: 1199 YREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG---RENEQFRQLED 1255
Query: 306 S 306
S
Sbjct: 1256 S 1256
Score = 37.7 bits (86), Expect = 0.013
Identities = 23/84 (27%), Positives = 47/84 (55%), Gaps = 11/84 (13%)
Query: 198 PVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEI 257
P++ R Q L E +++ P+ + + Q+ ++R+R++ ++ EEE Q
Sbjct: 789 PLREQRERQ-LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ-------- 839
Query: 258 ELLKRQQKLEQLELEKQKLQEEQE 281
L+R+++ +QL+ E+ LQE+QE
Sbjct: 840 --LQRRERAQQLQEEEDGLQEDQE 861
Score = 37.7 bits (86), Expect = 0.013
Identities = 37/171 (21%), Positives = 80/171 (46%), Gaps = 26/171 (15%)
Query: 138 EEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLIN 197
E +FREE +++ ++ E + ++ Y R I+ E E +RP++
Sbjct: 1722 ERKFREE-------EQLRQETEQEQLRRQERY---RKILEE---------EQLRPEREEQ 1762
Query: 198 PVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEI 257
++ + E + Q+R + + Q+ K + ++ ++Q+ EE Q + +
Sbjct: 1763 QLRRQERDRKFREEEQLRQER---EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDG 1819
Query: 258 ELLKRQQKLEQLELEKQKLQEEQEN---APEFVKVKGNLRRTGQEVAQAQE 305
+ +++L QLE ++Q+L++E++ A E + RR QE+ Q +E
Sbjct: 1820 KYRWEEEQL-QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEE 1869
Score = 37.4 bits (85), Expect = 0.017
Identities = 36/170 (21%), Positives = 77/170 (45%), Gaps = 11/170 (6%)
Query: 136 PKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKL 195
P EE+ R + LEL +K + + + +D E ++ + + +KL
Sbjct: 205 PDEEQLRRR-ELLELRRKGREEKQQQRRERQDRVFQEEE---EKEWRKRETVLRKEEEKL 260
Query: 196 INPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDL 255
+ E L +R + + E ++ ++ +R+Q +++K+EE ++++ +
Sbjct: 261 QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE 320
Query: 256 EIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
E +R++ +Q E +Q+L+ EQE E LRR +E + Q+
Sbjct: 321 RREQQERRE--QQEERREQQLRREQEERRE-----QQLRREQEEERREQQ 363
Score = 37.4 bits (85), Expect = 0.017
Identities = 35/151 (23%), Positives = 72/151 (47%), Gaps = 8/151 (5%)
Query: 142 REEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLINPVKT 201
REE K LEQ+ + + + L+ R ++ + E R ++ + +
Sbjct: 552 REEEK--RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE--RLEQRLKREEV 607
Query: 202 SRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEE--AQKKKSDLEIEL 259
R Q+ RE + ++ + + L+ ++ +R Q ++++++E Q+ K + E E
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Query: 260 LKRQQKLEQLE--LEKQKLQEEQENAPEFVK 288
L+++ K E E E++ +EEQE A E +K
Sbjct: 668 LEQRLKREHEEERREQELAEEEQEQARERIK 698
Score = 37.0 bits (84), Expect = 0.022
Identities = 27/106 (25%), Positives = 55/106 (51%), Gaps = 12/106 (11%)
Query: 203 RNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKR 262
R Q L RE ++R + + E ++ ++R++ Q+ + +EEE +++ LE E +
Sbjct: 442 RREQRLKRE---QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 263 QQKLEQLELEKQ---------KLQEEQENAPEFVKVKGNLRRTGQE 299
QQ+ + +L ++ K QEE+E + ++ + LRR +E
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Score = 36.6 bits (83), Expect = 0.029
Identities = 34/164 (20%), Positives = 76/164 (46%), Gaps = 9/164 (5%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
+EEE R++ E E+++ E+++ + ++ + PE R Q+L+
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVERLEQE------ERREQRLKREEPEEERRQQLL 634
Query: 197 -NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDL 255
+ + R Q L RE ++R + + E +++ ++ KR+ +++E+E +++ +
Sbjct: 635 KSEEQEERRQQQLRRE--QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
Query: 256 EIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQE 299
E +K + Q +LE + + + K +G RR QE
Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQE 736
Score = 36.2 bits (82), Expect = 0.037
Identities = 26/106 (24%), Positives = 59/106 (55%), Gaps = 7/106 (6%)
Query: 200 KTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIEL 259
+T R+ Q+ ++ L KR + + K+ E+ +R+Q +++E++ ++++ + +
Sbjct: 463 ETERHEQERRKQQL---KRDQEEERRERWLKLEEEERREQQ-ERREQQLRREQEERREQR 518
Query: 260 LKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
LKRQ++ E+L+ Q+L+ EQ+ E + + L + +E QE
Sbjct: 519 LKRQEEEERLQ---QRLRSEQQLRREQEERREQLLKREEEKRLEQE 561
Score = 35.4 bits (80), Expect = 0.064
Identities = 22/85 (25%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Query: 203 RNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKE------EEAQKKKSDLE 256
R Q LHR+ + PQ + + ++ + RD+ +++E EE Q ++ + +
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
Query: 257 IELLKRQQKLEQLELEKQKLQEEQE 281
+ + +Q+L + E E++ LQEEQ+
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQ 1715
Score = 35.0 bits (79), Expect = 0.083
Identities = 17/52 (32%), Positives = 36/52 (69%), Gaps = 2/52 (3%)
Query: 229 QKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQ 280
++ + +++RD+ K +EEE Q ++ + E + L+ +Q+L + ELE++ +EEQ
Sbjct: 1681 EQQLRRQERDR--KFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
Score = 34.7 bits (78), Expect = 0.11
Identities = 27/115 (23%), Positives = 60/115 (52%), Gaps = 12/115 (10%)
Query: 171 ITRSIMAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQK 230
+ + E ++++ EL R ++ R Q+ R+ ++ L + + L++
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREER------EKRRRQEQERQY--REEEQLQQEEEQLLRE 946
Query: 231 VMEKRKRDQVIKQ--KEEEAQKKKSDL--EIELLKRQQKLEQLELEKQKLQEEQE 281
EKR+R + +Q K+++ Q+K+ L E +R+Q+ E+ E+++LQ+E+E
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001
Score = 34.3 bits (77), Expect = 0.14
Identities = 30/144 (20%), Positives = 62/144 (43%), Gaps = 6/144 (4%)
Query: 142 REEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLINPVKT 201
+E + + ++ + E + K++ R E + ++ E R Q+ T
Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE------T 1334
Query: 202 SRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLK 261
R ++ + L +++ L Q + + E R ++Q K EEE + ++ + E + LK
Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLK 1394
Query: 262 RQQKLEQLELEKQKLQEEQENAPE 285
+Q+L E E+Q Q+ E
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFRE 1418
Score = 33.9 bits (76), Expect = 0.19
Identities = 34/161 (21%), Positives = 77/161 (47%), Gaps = 15/161 (9%)
Query: 136 PKEEEF-REEPKCLELEQKMTSDSPP---EDIDHKDSYLIT-RSIMAEPDYIEDDNPELI 190
P+EE+ REE K + + + + E+ + K T R E +++ + +
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL 1353
Query: 191 RPQKLINPVKTSR-NHQDLHRELLMNQKRGLAPQNKPELQKVMEK---RKRDQVIKQ--- 243
R Q+ + HQ+ R+ L ++R + + + K ++ ++R+Q ++Q
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413
Query: 244 ---KEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQE 281
+EEE Q + + + + + +Q++ + E E++ L+EEQ+
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Score = 33.9 bits (76), Expect = 0.19
Identities = 36/168 (21%), Positives = 80/168 (47%), Gaps = 16/168 (9%)
Query: 138 EEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLIN 197
+ +FREE + L+ ++ D ++ L R ++E++ L R ++
Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERDRKFREEEL--RHQEQGRKFLEEEQ-RLRRQERERK 1391
Query: 198 PVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSD--- 254
+K + + RE + Q R + E ++ + +++RD+ +++E++ ++++ +
Sbjct: 1392 FLKEEQQLRCQEREQQLRQDRD---RKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448
Query: 255 LEIELLKRQQKLEQLELEKQKLQE-------EQENAPEFVKVKGNLRR 295
LE E RQ++ + E+Q LQE QE +F++ + LRR
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRR 1496
Score = 33.5 bits (75), Expect = 0.24
Identities = 35/155 (22%), Positives = 67/155 (43%), Gaps = 20/155 (12%)
Query: 138 EEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLIN 197
E ++REE + + E+++ + P + + + R E + ++ + +L+R ++
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEP----EKRRRQELERQYREEEE-LQQEEEQLLREEQ--E 1189
Query: 198 PVKTSRNHQDLHRELLMNQKR-----------GLAPQNKPELQKVMEKRKRDQVIKQKEE 246
+ R Q E L QKR L Q +PE + + K K +E
Sbjct: 1190 KRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK--VYCKGREN 1247
Query: 247 EAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQE 281
E ++ D ++ + QQ L+ L E+Q+ EQE
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE 1282
Score = 32.7 bits (73), Expect = 0.41
Identities = 28/145 (19%), Positives = 68/145 (46%), Gaps = 17/145 (11%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
++ +FREE + L +++ E + R + E + + R ++ +
Sbjct: 1412 RDRKFREEEQQLSRQERDRKFREEEQQVRRQER--ERKFLEEEQQLRQERHRKFREEEQL 1469
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLE 256
R Q LHR+ +++ L++ + R++++ K +E+E + ++ E
Sbjct: 1470 ---LQEREEQQLHRQ----------ERDRKFLEEEQQLRRQERDRKFREQELRSQEP--E 1514
Query: 257 IELLKRQQKLEQLELEKQKLQEEQE 281
+ L+ +Q+L + + +++ LQEEQ+
Sbjct: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQ 1539
Score = 32.7 bits (73), Expect = 0.41
Identities = 26/145 (17%), Positives = 66/145 (45%), Gaps = 1/145 (0%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
++ +FRE+ + L+ ++ D + R E D + + ++L+
Sbjct: 1617 RDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLE 256
+ + + +++ L Q + E++ R Q +++K E ++ + + E
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
Query: 257 IELLKRQQKLEQLELEKQKLQEEQE 281
E L+RQ++ ++ LE+++L+ E+E
Sbjct: 1737 QEQLRRQERYRKI-LEEEQLRPERE 1760
Score = 32.0 bits (71), Expect = 0.70
Identities = 36/171 (21%), Positives = 78/171 (45%), Gaps = 24/171 (14%)
Query: 138 EEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLIN 197
+E+ R+E + L+ E++ E ++ R E + ++ + +L+R ++
Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR----EEEQLQQEEEQLLREER--- 948
Query: 198 PVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEI 257
R Q+ R+ ++K LQ+ E+ ++ K++ +E +KK + E
Sbjct: 949 ---EKRRRQERERQYRKDKK----------LQQKEEQLLGEEPEKRRRQEREKKYRE-EE 994
Query: 258 ELLKRQQKLEQLELEKQKLQE---EQENAPEFVKVKGNLRRTGQEVAQAQE 305
EL + +++L + E EK++ QE + E + + L R +E + QE
Sbjct: 995 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045
Score = 32.0 bits (71), Expect = 0.70
Identities = 32/177 (18%), Positives = 86/177 (48%), Gaps = 11/177 (6%)
Query: 137 KEEEFREEP---KCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQ 193
+EEE R + K LE EQ++ ++ L R E +D + + +
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL--RCQEREQQLRQDRDRKFREEE 1420
Query: 194 KLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEK--RKRDQVIKQKEEEAQKK 251
+ ++ + R ++ +++ ++ + + +L++ + R+ +Q+++++EE+ Q
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ-QLH 1479
Query: 252 KSDLEIELLKRQQKLEQLELEKQKLQEE---QENAPEFVKVKGNLRRTGQEVAQAQE 305
+ + + + L+ +Q+L + E +++ ++E QE +F++ + L R ++ QE
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE 1536
Score = 32.0 bits (71), Expect = 0.70
Identities = 30/149 (20%), Positives = 66/149 (44%), Gaps = 17/149 (11%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
++ +FREE + + ++ S D R E ++ + +RPQ+
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESD----------RKFREEEQLRQEREEQQLRPQQRD 1818
Query: 197 NPVKTSRNHQDLH-RELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDL 255
+ L +E + Q+R + + + + R+ +Q + Q+EE QK++ +
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEE--QKRRQER 1876
Query: 256 EIEL----LKRQQKLEQLELEKQKLQEEQ 280
E +L ++RQQK EQ + +++ ++
Sbjct: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 31.2 bits (69), Expect = 1.2
Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 225 KPELQKVMEKRKRDQVIKQKEEEAQK----KKSDLEIELLKR-----QQKLEQLELEKQK 275
KP LQ+ + RK Q+++++EEE Q+ K+ E E R QQ+ EQL E+++
Sbjct: 892 KPALQEQL--RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 276 LQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
+ QE ++ K K ++ Q + + E
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPE 979
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/86 (24%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
Query: 199 VKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQK--KKSDLE 256
++ ++ QDL L Q+R + + Q+ + +Q+ +++++EA++ +KS E
Sbjct: 1258 LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE 1317
Query: 257 IELLK--RQQKLEQLELEKQKLQEEQ 280
+LL+ R++K + E +++ +EEQ
Sbjct: 1318 KQLLREEREEKRRRQETDRKFREEEQ 1343
Score = 30.4 bits (67), Expect = 2.0
Identities = 14/63 (22%), Positives = 40/63 (63%), Gaps = 3/63 (4%)
Query: 223 QNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQEN 282
+ +P ++ +++++++ + + EE+++K++ +E RQ++ E+L ++Q+ QE +E
Sbjct: 130 EEEPGQRRRQKRQEQERELAEGEEQSEKQE---RLEQRDRQRRDEELWRQRQEWQEREER 186
Query: 283 APE 285
E
Sbjct: 187 RAE 189
Score = 30.4 bits (67), Expect = 2.0
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 9/93 (9%)
Query: 213 LMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELE 272
L ++ GL Q E ++ E+R+ + Q EEE ++++ L + EQL E
Sbjct: 849 LQEEEDGL--QEDQERRRSQEQRRDQKWRWQLEEERKRRRH----TLYAKPALQEQLRKE 902
Query: 273 KQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
+Q LQEE+E E + + RR ++ Q +E
Sbjct: 903 QQLLQEEEE---ELQREEREKRRRQEQERQYRE 932
Score = 30.4 bits (67), Expect = 2.0
Identities = 43/181 (23%), Positives = 81/181 (44%), Gaps = 35/181 (19%)
Query: 146 KCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLINPVKTSRNH 205
K LE EQ++ ++ D K RS E ++E++ +L R Q+ K +
Sbjct: 1486 KFLEEEQQLRR----QERDRKFREQELRSQEPERKFLEEEQ-QLHRQQR---QRKFLQEE 1537
Query: 206 QDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEE------------EAQKKKS 253
Q L R+ Q+R + E +++ ++R+ Q+ +Q+ + + Q++K
Sbjct: 1538 QQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKF 1597
Query: 254 DLEIELLKRQQKLEQLELEK--------QKLQE-------EQENAPEFVKVKGNLRRTGQ 298
+ + L+RQ+ +QL E+ Q LQE QE +F++ + LRR +
Sbjct: 1598 MEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER 1657
Query: 299 E 299
E
Sbjct: 1658 E 1658
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 47.0 bits (110), Expect = 2e-05
Identities = 50/248 (20%), Positives = 120/248 (48%), Gaps = 19/248 (7%)
Query: 59 KAGRQPRHPSAEGAPEKRQDSSTHAERNG---SANRNSSHRTAAQPAETPEDVPGSLDDG 115
K + R S + +++ S ++RN S +R+ S TA E + S D
Sbjct: 22 KKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERASSPPDR 81
Query: 116 ADCEAVVFHASIPRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSI 175
D +F ++ + S +D ++ E E+ E ++K+ E + +++ +
Sbjct: 82 ID----IFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEEL 137
Query: 176 MAE--PDYIEDDNPELIRPQKLINPVKTSRN--HQDLHRELLMNQKRGLAPQNKPELQKV 231
+A+ + +E E+ R +++ V+ ++ + L EL ++ LA Q E ++
Sbjct: 138 VAKRVEEELEKRKDEIER--EVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEER 195
Query: 232 MEKRKRDQVIKQ---KEEEAQKKKSDLEIELLKRQQKL--EQLELEKQKLQEEQENAPEF 286
++ + ++++++ K EAQ K ++ ++ +++ Q+K+ E+++LE+++ Q +Q+ +
Sbjct: 196 AKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQER-QRQQKEEQKI 254
Query: 287 VKVKGNLR 294
+ KG R
Sbjct: 255 ILGKGKSR 262
Score = 42.0 bits (97), Expect = 7e-04
Identities = 37/152 (24%), Positives = 75/152 (49%), Gaps = 13/152 (8%)
Query: 156 SDSPPEDIDHKDSYLITRSIMAEPDYIEDDNP--ELIRPQKLINPVKTSRNHQDLHRELL 213
+ SPP+ ID + RS + E E++ E R +K+ Q++ +L+
Sbjct: 75 ASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKI--------RQQEIEEKLI 126
Query: 214 MNQK-RGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELE 272
+ R + +++ +EKRK D++ ++ ++ K +E +LL+ ++ Q EL
Sbjct: 127 EEETARRVEELVAKRVEEELEKRK-DEIEREVLRRVEEAKRIMEKQLLEELERQRQAELA 185
Query: 273 KQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQ 304
QK +EE+E A +++ L +++A+AQ
Sbjct: 186 AQKAREEEERAKR-EELERILEENNRKIAEAQ 216
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 46.2 bits (108), Expect = 4e-05
Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 2/104 (1%)
Query: 183 EDDNPELIRPQKLINPVKTSRNHQDLHRE-LLMNQKRGLAPQNKPELQKVMEKRKRDQVI 241
E++ I Q+L R Q LH E LL QK + K E ++ +KR+ +Q
Sbjct: 46 EEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQER 105
Query: 242 KQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPE 285
K KE+ ++++ + E E KRQ+K E+ E QK+ ++ EN E
Sbjct: 106 KLKEQWEEQQRKEREEEEQKRQEKKEK-EEALQKMLDQAENELE 148
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
Query: 230 KVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQ--LELEKQKLQEE----QENA 283
K +++KR Q + + + +K + E ++ QQ E+ LE E+Q+L EE ++ A
Sbjct: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKA 82
Query: 284 PEFVKVKGNLRRTGQEVAQAQE 305
E ++K ++ + QE
Sbjct: 83 QEEFRIKKEKEEAAKKRQEEQE 104
Score = 28.5 bits (62), Expect = 7.8
Identities = 15/60 (25%), Positives = 35/60 (58%)
Query: 221 APQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQ 280
AP+ +K K+ R + K+K ++ +++ + L L ++++ E +E+Q+L+EE+
Sbjct: 3 APEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEK 62
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 45.8 bits (107), Expect = 5e-05
Identities = 32/130 (24%), Positives = 71/130 (54%), Gaps = 10/130 (7%)
Query: 181 YIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQK--RGLAPQNKPELQKVMEKRKRD 238
Y+ P+ I Q++ + ++ + + R +L N+K R +A + K ++++ EK +
Sbjct: 291 YMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIER--EKEELM 348
Query: 239 QVIKQKEEEAQKKKSDLEIE---LLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRR 295
+ +KQ EE+ +K + +LE + L+ +Q+ ++ + E +KL +E++ A E K L +
Sbjct: 349 ERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEE---AKEALLQ 405
Query: 296 TGQEVAQAQE 305
++ + QE
Sbjct: 406 ASRDQKKTQE 415
Score = 38.1 bits (87), Expect = 0.010
Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 7/135 (5%)
Query: 178 EPDYIEDDNPELIRPQKLINPVKTSRNHQDLH----RELLMNQKRGLAPQNKPELQKV-M 232
E + IE + EL+ K I +T + Q+L R L + Q+R A +L K
Sbjct: 336 EKEKIEREKEELMERLKQIEE-QTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQ 394
Query: 233 EKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQ-ENAPEFVKVKG 291
E + + + Q + +K + L +E+ + ++ QLE+ +QK + E E + V+
Sbjct: 395 EAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQE 454
Query: 292 NLRRTGQEVAQAQES 306
+L +T E+ A +
Sbjct: 455 DLEKTRAELKTAMST 469
>gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens]
Length = 2817
Score = 45.8 bits (107), Expect = 5e-05
Identities = 44/152 (28%), Positives = 69/152 (45%), Gaps = 33/152 (21%)
Query: 175 IMAEPDYIEDDN---------PELIRPQKLINPVKT---SRNHQDLHRELLMNQKRGLAP 222
++ + YIED L RP LI K + QDL L Q + L
Sbjct: 2543 VLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDL-ANLQKQQAQYLEE 2601
Query: 223 QNKPELQ---KVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQK-------LEQLELE 272
+ + E + + E R+R+ ++ Q+EEE Q+ + DLE E + QQK LE+L
Sbjct: 2602 KRRREREWEARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAA 2661
Query: 273 KQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQ 304
+++L+ EQE LRR + ++Q Q
Sbjct: 2662 QKQLEREQE----------QLRREAERLSQRQ 2683
>gi|21493031 A-kinase anchor protein 13 isoform 3 [Homo sapiens]
Length = 1058
Score = 45.8 bits (107), Expect = 5e-05
Identities = 44/152 (28%), Positives = 69/152 (45%), Gaps = 33/152 (21%)
Query: 175 IMAEPDYIEDDN---------PELIRPQKLINPVKT---SRNHQDLHRELLMNQKRGLAP 222
++ + YIED L RP LI K + QDL L Q + L
Sbjct: 784 VLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDL-ANLQKQQAQYLEE 842
Query: 223 QNKPELQ---KVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQK-------LEQLELE 272
+ + E + + E R+R+ ++ Q+EEE Q+ + DLE E + QQK LE+L
Sbjct: 843 KRRREREWEARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAA 902
Query: 273 KQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQ 304
+++L+ EQE LRR + ++Q Q
Sbjct: 903 QKQLEREQE----------QLRREAERLSQRQ 924
>gi|21493029 A-kinase anchor protein 13 isoform 2 [Homo sapiens]
Length = 2813
Score = 45.8 bits (107), Expect = 5e-05
Identities = 44/152 (28%), Positives = 69/152 (45%), Gaps = 33/152 (21%)
Query: 175 IMAEPDYIEDDN---------PELIRPQKLINPVKT---SRNHQDLHRELLMNQKRGLAP 222
++ + YIED L RP LI K + QDL L Q + L
Sbjct: 2539 VLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDL-ANLQKQQAQYLEE 2597
Query: 223 QNKPELQ---KVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQK-------LEQLELE 272
+ + E + + E R+R+ ++ Q+EEE Q+ + DLE E + QQK LE+L
Sbjct: 2598 KRRREREWEARERELREREALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAA 2657
Query: 273 KQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQ 304
+++L+ EQE LRR + ++Q Q
Sbjct: 2658 QKQLEREQE----------QLRREAERLSQRQ 2679
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 45.4 bits (106), Expect = 6e-05
Identities = 30/147 (20%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Query: 137 KEEEFRE-EPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKL 195
+EE+ RE E K E+K+ + + I + + I++ E+ R ++
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Query: 196 INPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEK-RKRDQVIKQKEEEAQKKKSD 254
I + R + +E M ++ + + E+ + EK R+ +++++ +EE+ ++ +
Sbjct: 397 IREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456
Query: 255 LEIELLKRQQKLEQLELEKQKLQEEQE 281
++ E K Q++ E+++ +++K+QE++E
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEE 483
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/169 (18%), Positives = 79/169 (46%), Gaps = 3/169 (1%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
+E+ +R+E K E E+KM + + + + + I + ++ R ++ I
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI 355
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLE 256
+ Q+ E + Q+ + Q++ ++ E ++++ I+++EE+ Q+K E
Sbjct: 356 REQEEKIREQE---EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 257 IELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
++ ++ +K+ + E E + +E+ E ++ + R +E Q +E
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461
Score = 39.7 bits (91), Expect = 0.003
Identities = 28/146 (19%), Positives = 76/146 (52%), Gaps = 16/146 (10%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPP-EDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKL 195
+EE +R+E K ELE+ M +++ K + E + +++ ++ R ++
Sbjct: 426 EEEMWRQEEKIRELEEMMQDQEEKLREVEEK--------MQEEEEKMQEQEEKIQRQEEK 477
Query: 196 INPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQK---KK 252
I + + +E L+ Q+ + Q + ++ + ++++ ++++EE+ Q+ K
Sbjct: 478 IQ----EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM 533
Query: 253 SDLEIELLKRQQKLEQLELEKQKLQE 278
+ E+ L ++++K+++ E+ Q+L+E
Sbjct: 534 REQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 38.5 bits (88), Expect = 0.008
Identities = 38/176 (21%), Positives = 85/176 (48%), Gaps = 23/176 (13%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
+E+ +R+E K E E+K+ ED + I + + I + ++ R ++ I
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQ---EDKMWRQE----EKIREQEEKIREQEEKMWRQEEKI 376
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKR----DQVIKQKEEEA---Q 249
Q+ E + Q+ + Q + +K+ + K+ D+ I+++EEE +
Sbjct: 377 REQDEKIQEQE---EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 250 KKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
+K +LE + +++KL ++E +K+QEE+E E + ++R +++ + +E
Sbjct: 434 EKIRELEEMMQDQEEKLREVE---EKMQEEEEKMQE---QEEKIQRQEEKIQEQEE 483
Score = 34.3 bits (77), Expect = 0.14
Identities = 31/157 (19%), Positives = 77/157 (49%), Gaps = 22/157 (14%)
Query: 133 IDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRP 192
I +EE +R+E K E E+K ++ + + + + I + E+ R
Sbjct: 383 IQEQEEEMWRQEEKIREQEEKRQEKMWRQE----------KKMREQDEKIREQEEEMWRQ 432
Query: 193 QKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKK 252
++ I ++ QD +L +++ + K + Q+ +R+ +++ +Q+E+ +++K
Sbjct: 433 EEKIRELEEMM--QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490
Query: 253 SDLEIELLKRQQKL----EQLELEKQKLQEEQENAPE 285
LLK+++K+ E++ +++K+ E++E E
Sbjct: 491 ------LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
Score = 33.5 bits (75), Expect = 0.24
Identities = 33/150 (22%), Positives = 76/150 (50%), Gaps = 11/150 (7%)
Query: 142 REEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDY------IEDDNPELIRPQKL 195
R+ P LEL + +D E++ K++ L + + E + ++D +L R Q L
Sbjct: 199 RDAPS-LELYRNTITD---EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
Query: 196 INPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDL 255
+ + L +EL + A + EL ++ +++ +++ +Q+E+ ++++
Sbjct: 255 LPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC 314
Query: 256 EIELLKRQQKLEQLELEKQKLQEEQENAPE 285
E EL R+Q+ E++ +++K+ E++E E
Sbjct: 315 EQELKIREQE-EKMWRQEEKMHEQEEKIRE 343
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 45.4 bits (106), Expect = 6e-05
Identities = 30/147 (20%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Query: 137 KEEEFRE-EPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKL 195
+EE+ RE E K E+K+ + + I + + I++ E+ R ++
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Query: 196 INPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEK-RKRDQVIKQKEEEAQKKKSD 254
I + R + +E M ++ + + E+ + EK R+ +++++ +EE+ ++ +
Sbjct: 397 IREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456
Query: 255 LEIELLKRQQKLEQLELEKQKLQEEQE 281
++ E K Q++ E+++ +++K+QE++E
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEE 483
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/169 (18%), Positives = 79/169 (46%), Gaps = 3/169 (1%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
+E+ +R+E K E E+KM + + + + + I + ++ R ++ I
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI 355
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLE 256
+ Q+ E + Q+ + Q++ ++ E ++++ I+++EE+ Q+K E
Sbjct: 356 REQEEKIREQE---EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 257 IELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
++ ++ +K+ + E E + +E+ E ++ + R +E Q +E
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461
Score = 39.7 bits (91), Expect = 0.003
Identities = 28/146 (19%), Positives = 76/146 (52%), Gaps = 16/146 (10%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPP-EDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKL 195
+EE +R+E K ELE+ M +++ K + E + +++ ++ R ++
Sbjct: 426 EEEMWRQEEKIRELEEMMQDQEEKLREVEEK--------MQEEEEKMQEQEEKIQRQEEK 477
Query: 196 INPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQK---KK 252
I + + +E L+ Q+ + Q + ++ + ++++ ++++EE+ Q+ K
Sbjct: 478 IQ----EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM 533
Query: 253 SDLEIELLKRQQKLEQLELEKQKLQE 278
+ E+ L ++++K+++ E+ Q+L+E
Sbjct: 534 REQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 38.5 bits (88), Expect = 0.008
Identities = 38/176 (21%), Positives = 85/176 (48%), Gaps = 23/176 (13%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
+E+ +R+E K E E+K+ ED + I + + I + ++ R ++ I
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQ---EDKMWRQE----EKIREQEEKIREQEEKMWRQEEKI 376
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKR----DQVIKQKEEEA---Q 249
Q+ E + Q+ + Q + +K+ + K+ D+ I+++EEE +
Sbjct: 377 REQDEKIQEQE---EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 250 KKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
+K +LE + +++KL ++E +K+QEE+E E + ++R +++ + +E
Sbjct: 434 EKIRELEEMMQDQEEKLREVE---EKMQEEEEKMQE---QEEKIQRQEEKIQEQEE 483
Score = 34.3 bits (77), Expect = 0.14
Identities = 31/157 (19%), Positives = 77/157 (49%), Gaps = 22/157 (14%)
Query: 133 IDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRP 192
I +EE +R+E K E E+K ++ + + + + I + E+ R
Sbjct: 383 IQEQEEEMWRQEEKIREQEEKRQEKMWRQE----------KKMREQDEKIREQEEEMWRQ 432
Query: 193 QKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKK 252
++ I ++ QD +L +++ + K + Q+ +R+ +++ +Q+E+ +++K
Sbjct: 433 EEKIRELEEMM--QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490
Query: 253 SDLEIELLKRQQKL----EQLELEKQKLQEEQENAPE 285
LLK+++K+ E++ +++K+ E++E E
Sbjct: 491 ------LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
Score = 33.1 bits (74), Expect = 0.32
Identities = 31/144 (21%), Positives = 73/144 (50%), Gaps = 10/144 (6%)
Query: 148 LELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDY------IEDDNPELIRPQKLINPVKT 201
LEL + +D E++ K++ L + + E + ++D +L R Q L+ +
Sbjct: 204 LELYRNTITD---EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQL 260
Query: 202 SRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLK 261
L +EL + A + EL ++ +++ +++ +Q+E+ ++++ E EL
Sbjct: 261 QVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKI 320
Query: 262 RQQKLEQLELEKQKLQEEQENAPE 285
R+Q+ E++ +++K+ E++E E
Sbjct: 321 REQE-EKMWRQEEKMHEQEEKIRE 343
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 45.1 bits (105), Expect = 8e-05
Identities = 57/258 (22%), Positives = 108/258 (41%), Gaps = 14/258 (5%)
Query: 33 NTRESASFNQSGVADTHSTVRVQPVAKAGRQPRHPSAEGAPEKRQDSSTHAERNGSANRN 92
N+ + S + T V + + P PS P + S + ER S++
Sbjct: 349 NSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGK-GPSFNQERGTSSHLP 407
Query: 93 SSHRTAAQPAETPED--VPG------SLDDGADCEAVVFHASIPRPSIIDTPKEEEFREE 144
+ AQ P+ VPG S AD + + + I + R E
Sbjct: 408 PPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRRE 467
Query: 145 PKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRP-QKLINPVKTSR 203
+ +E++ + + E + D L P+ I + E R +K + +
Sbjct: 468 EEERRMEEQRKA-ACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQE 526
Query: 204 NHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQ 263
++ ++ Q++ + + E Q+ MEK ++ + K+KE E QK+K + E++ +K Q
Sbjct: 527 REKEREKDRERQQEKEKELEKEQEKQREMEKERKQE--KEKELERQKEK-EKELQKMKEQ 583
Query: 264 QKLEQLELEKQKLQEEQE 281
+K +LE E++KL+E+ E
Sbjct: 584 EKECELEKEREKLEEKIE 601
Score = 38.9 bits (89), Expect = 0.006
Identities = 26/85 (30%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Query: 200 KTSRNHQDLHRELLMNQK--RGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEI 257
K Q+ +EL Q+ R + + K E +K +E++K + QK +E Q+K+ +LE
Sbjct: 533 KDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKE-QEKECELEK 591
Query: 258 ELLKRQQKLEQLELEKQKLQEEQEN 282
E K ++K+E E + + E+QE+
Sbjct: 592 EREKLEEKIEPREPNLEPMVEKQES 616
Score = 35.4 bits (80), Expect = 0.064
Identities = 22/81 (27%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 211 ELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLE 270
E + ++R + + EL+K E+ + + K +E + Q+K+ +LE E K+++ ++ +
Sbjct: 502 EEIREREREKEREREKELEKEQEQEREKEREKDRERQ-QEKEKELEKEQEKQREMEKERK 560
Query: 271 LEKQK-LQEEQENAPEFVKVK 290
EK+K L+ ++E E K+K
Sbjct: 561 QEKEKELERQKEKEKELQKMK 581
Score = 34.7 bits (78), Expect = 0.11
Identities = 26/106 (24%), Positives = 53/106 (50%), Gaps = 10/106 (9%)
Query: 193 QKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKK 252
+K +P + ++ RE ++ + + E +K E+++ + +KE+E Q+
Sbjct: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQR-- 553
Query: 253 SDLEIELLKRQQKLEQLELEKQKLQE-----EQENAPEFVKVKGNL 293
E+E ++Q+K ++LE +K+K +E EQE E K + L
Sbjct: 554 ---EMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKL 596
Score = 33.5 bits (75), Expect = 0.24
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 33/167 (19%)
Query: 128 PRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNP 187
P P I + E+ RE K LE EQ+ + E + ++
Sbjct: 499 PSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQ---------------QEKEK 543
Query: 188 ELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEE 247
EL + Q+ ++ R Q+ +EL + + E +K ++K K ++KE E
Sbjct: 544 ELEKEQEKQREMEKERK-QEKEKEL----------ERQKEKEKELQKMKE----QEKECE 588
Query: 248 AQKKKSDLEIELLKRQQKLEQLELEKQKLQE--EQENAPEFVKVKGN 292
+K++ LE ++ R+ LE + +EKQ+ + +E P F + N
Sbjct: 589 LEKEREKLEEKIEPREPNLEPM-VEKQESENSCNKEEEPVFTRQDSN 634
Score = 32.7 bits (73), Expect = 0.41
Identities = 26/95 (27%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
Query: 214 MNQKRG-LAPQNKPELQKVMEKRKRDQVIKQKEEE-AQKKKSDLEIELLKRQQKLEQLEL 271
+++K G L Q PE + E+ K + K+ E+E Q+++ + E + ++Q+K ++LE
Sbjct: 488 LDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEK 547
Query: 272 EKQKLQE-EQENAPEFVKVKGNLRRTGQEVAQAQE 305
E++K +E E+E E K + +E+ + +E
Sbjct: 548 EQEKQREMEKERKQEKEKELERQKEKEKELQKMKE 582
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 44.7 bits (104), Expect = 1e-04
Identities = 32/90 (35%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Query: 221 APQNKPEL-QKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKL---EQLELEKQKL 276
A + K EL +KV E + + +Q++ EAQ + ++LE++L QQK E++ EK +L
Sbjct: 641 AQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQL 700
Query: 277 QEEQENAPEFVKV-KGNLRRTGQEVAQAQE 305
QE+ + E +KV KG+L + A A E
Sbjct: 701 QEQLQALKESLKVTKGSLEEEKRRAADALE 730
Score = 35.4 bits (80), Expect = 0.064
Identities = 41/188 (21%), Positives = 82/188 (43%), Gaps = 20/188 (10%)
Query: 135 TPKEEEFREEPKCLELEQKMTSDS-----------PPEDIDHKDSYLITR---SIMAEPD 180
+P + + E + LEL++ +S S P DI + + R + E
Sbjct: 169 SPPSHQAKREIRFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERS 228
Query: 181 YIEDDNPELIRPQKLINP--VKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRD 238
++ EL +KL+ + + Q + R L+N+K+ +P EL+ E R ++
Sbjct: 229 NRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELE---ELRDKN 285
Query: 239 QVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQ-EEQENAPEFVKVKGNLRRTG 297
+ + + E K+ DL+ E + +K+ QL E L + +E A +++ L
Sbjct: 286 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345
Query: 298 QEVAQAQE 305
+E ++A +
Sbjct: 346 EEHSKATQ 353
Score = 32.3 bits (72), Expect = 0.54
Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 7/76 (9%)
Query: 230 KVMEKRKRDQVIKQKEEEAQKKKSDLE-IELLKRQQKLEQLELEKQKLQEEQENAPEFVK 288
KV+E+R+R Q EE QK + +E +E+ +R+Q + EL K+ +Q + + K
Sbjct: 1518 KVLEERQRFQ------EERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQK 1571
Query: 289 VKGNLRRTGQEVAQAQ 304
+K + G+ +AQ
Sbjct: 1572 LKAVQAQGGESQQEAQ 1587
Score = 30.4 bits (67), Expect = 2.0
Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 5/57 (8%)
Query: 229 QKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPE 285
Q EKR R+++ E++++ L ELL+ Q++L +L +QK+ E++ A +
Sbjct: 1374 QAAAEKRHREEL-----EQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQ 1425
>gi|4758472 G protein pathway suppressor 2 [Homo sapiens]
Length = 327
Score = 44.3 bits (103), Expect = 1e-04
Identities = 30/104 (28%), Positives = 57/104 (54%), Gaps = 14/104 (13%)
Query: 187 PELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEE 246
P L+ KL N + + LHR ++M ++R Q + E+ K+ME+ K KEE
Sbjct: 2 PALLERPKLSNAMARA-----LHRHIMMERER--KRQEEEEVDKMMEQ-------KMKEE 47
Query: 247 EAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVK 290
+ ++KK ++E + + K + L+LE++ L ++E F+++K
Sbjct: 48 QERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 43.1 bits (100), Expect = 3e-04
Identities = 43/185 (23%), Positives = 92/185 (49%), Gaps = 13/185 (7%)
Query: 102 AETPEDVPG-SLDDGADCEAVVFHASIPRPSIIDTPKEEEFREEPKCLELEQKMTSDSPP 160
+++PE +PG +L+D A+ + +P + D E++ EPK L+QK +
Sbjct: 1324 SKSPESLPGPALED----IAIKWEDKVP--GLKDRTSEQKKEPEPKDEVLQQKDKTLEHK 1377
Query: 161 EDIDHKDS--YLITRSIMAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKR 218
E ++ KD+ Y ++ + + ++ + L + + + T+ +D + L + +
Sbjct: 1378 EVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKD---KALEPKDK 1434
Query: 219 GLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQE 278
L ++K QK ++D+ ++QK+ ++K LE + +QK LE +K+K+ E
Sbjct: 1435 DLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLE-QKEKIPE 1493
Query: 279 EQENA 283
E++ A
Sbjct: 1494 EKDKA 1498
Score = 37.0 bits (84), Expect = 0.022
Identities = 38/158 (24%), Positives = 68/158 (43%), Gaps = 23/158 (14%)
Query: 136 PKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKL 195
PK+++ E+ K LE + K+ + + ++ KD+ L + EP + + + + QK
Sbjct: 1431 PKDKDLEEKDKALEQKDKIPEEKD-KALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKE 1489
Query: 196 INPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRD------------QVIKQ 243
P + ++ ++QK PE V E + RD Q +Q
Sbjct: 1490 KIPEE---------KDKALDQKVRSVEHKAPE-DTVAEMKDRDLEQTDKAPEQKHQAQEQ 1539
Query: 244 KEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQE 281
K++ ++KK LE + QK E LE Q L+E +
Sbjct: 1540 KDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQ 1577
Score = 34.7 bits (78), Expect = 0.11
Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 32/172 (18%)
Query: 136 PKEEEFREEPKCLELEQKMTSDSPPE-DIDHKDSYLITRS-IMAEPDYIEDDNPELIRPQ 193
P+E++ E K LEQK + P + D++ KD L + I E D D +R
Sbjct: 1450 PEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQK---VRSV 1506
Query: 194 KLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEK--RKRDQVIKQK------- 244
+ P T +D R+L K AP+ K + Q+ +K K+DQ ++QK
Sbjct: 1507 EHKAPEDTVAEMKD--RDLEQTDK---APEQKHQAQEQKDKVSEKKDQALEQKYWALGQK 1561
Query: 245 -------------EEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENA 283
+ Q+++S ++ + ++ + LE+ EK K EE+ A
Sbjct: 1562 DEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEA 1613
Score = 30.8 bits (68), Expect = 1.6
Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
Query: 210 RELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQL 269
++ + K + P++ QK +++ +KQ+++ ++K DLE + +QK + L
Sbjct: 1370 KDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKAL 1429
Query: 270 E------LEKQKLQEEQENAPE 285
E EK K E+++ PE
Sbjct: 1430 EPKDKDLEEKDKALEQKDKIPE 1451
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 43.1 bits (100), Expect = 3e-04
Identities = 39/177 (22%), Positives = 87/177 (49%), Gaps = 20/177 (11%)
Query: 128 PRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNP 187
P PSI + P+ + ++ L E ++ S+S + S + PD P
Sbjct: 397 PVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQSGKVI------PD--RSTKP 448
Query: 188 ELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEE 247
+ P ++ + +R H + LLM + + + EL++ ++ +++++ K+++E+
Sbjct: 449 VVFSPTLMLTDEEKARIHAET--ALLMEKNK-----QEKELRERQQEEQKEKLRKEEQEQ 501
Query: 248 AQKKKSDL-EIELLKRQQK----LEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQE 299
KKK + E E+ ++QQK +E+ E E+ K ++++ +A ++ G R++ E
Sbjct: 502 KAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKEITGVKRQSKSE 558
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 43.1 bits (100), Expect = 3e-04
Identities = 39/177 (22%), Positives = 87/177 (49%), Gaps = 20/177 (11%)
Query: 128 PRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNP 187
P PSI + P+ + ++ L E ++ S+S + S + PD P
Sbjct: 397 PVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQSGKVI------PD--RSTKP 448
Query: 188 ELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEE 247
+ P ++ + +R H + LLM + + + EL++ ++ +++++ K+++E+
Sbjct: 449 VVFSPTLMLTDEEKARIHAET--ALLMEKNK-----QEKELRERQQEEQKEKLRKEEQEQ 501
Query: 248 AQKKKSDL-EIELLKRQQK----LEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQE 299
KKK + E E+ ++QQK +E+ E E+ K ++++ +A ++ G R++ E
Sbjct: 502 KAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKEITGVKRQSKSE 558
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 43.1 bits (100), Expect = 3e-04
Identities = 39/177 (22%), Positives = 87/177 (49%), Gaps = 20/177 (11%)
Query: 128 PRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNP 187
P PSI + P+ + ++ L E ++ S+S + S + PD P
Sbjct: 397 PVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQSGKVI------PD--RSTKP 448
Query: 188 ELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEE 247
+ P ++ + +R H + LLM + + + EL++ ++ +++++ K+++E+
Sbjct: 449 VVFSPTLMLTDEEKARIHAET--ALLMEKNK-----QEKELRERQQEEQKEKLRKEEQEQ 501
Query: 248 AQKKKSDL-EIELLKRQQK----LEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQE 299
KKK + E E+ ++QQK +E+ E E+ K ++++ +A ++ G R++ E
Sbjct: 502 KAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKEITGVKRQSKSE 558
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 42.7 bits (99), Expect = 4e-04
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 7/96 (7%)
Query: 193 QKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKK- 251
++L + R Q+ + Q+R + + E Q ++R+R+Q Q E E Q++
Sbjct: 682 KRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQERE 741
Query: 252 ------KSDLEIELLKRQQKLEQLELEKQKLQEEQE 281
K L+ EL ++++K EQ L +++LQEEQE
Sbjct: 742 KALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 777
Score = 39.3 bits (90), Expect = 0.004
Identities = 57/277 (20%), Positives = 106/277 (38%), Gaps = 41/277 (14%)
Query: 52 VRVQPVAKAGRQPRHPSAEGAPEKRQDSSTHAERNGS----------ANRNSSHRTAAQP 101
+ V+ K G + + P E P + E NG+ AN + + AA
Sbjct: 363 LNVEVPQKVGSEQKEPPEEAEPVAAAEPEV-PENNGNNSWPHNDTEIANSTPNPKPAASS 421
Query: 102 AETPEDVPGSLDDGADCEAVVFHASIPRPSIIDTPKEEEFREEPKCLELEQKMTSDS--P 159
ETP EA A PR ++ +++ L+ EQ + + P
Sbjct: 422 PETPS--------AGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQP 473
Query: 160 PEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLINPVKTSRNHQDL----HRELLMN 215
P ++ + ++ + R Q L+ P R+ + L M+
Sbjct: 474 PRSKTPSSPCPASKVVRPLRTFLHT----VQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
Query: 216 QKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKL--------- 266
K + + L+ + K + +Q+ +QK EE ++++ LE LKR+++L
Sbjct: 530 PKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRR--LEEVKLKREERLRKVLQARER 587
Query: 267 -EQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQ 302
EQ++ EK+K E++ + K R +E A+
Sbjct: 588 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 624
Score = 38.9 bits (89), Expect = 0.006
Identities = 37/174 (21%), Positives = 80/174 (45%), Gaps = 19/174 (10%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
+EE R+ + E ++M + + I+ K + + ++ A+ + + ++ + K +
Sbjct: 574 REERLRKVLQARERVEQMKEEKKKQ-IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 632
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLE 256
V+ R ++ R L Q Q+ E+R ++ + K+KEEE ++ + E
Sbjct: 633 EEVEARRKQEEEARRLRWLQ------------QEEEERRHQELLQKKKEEEQERLRKAAE 680
Query: 257 IELLKRQQKLEQLELEKQKLQ------EEQENAPEFVKVKGNLRRTGQEVAQAQ 304
+ L Q++ E+ E E+++ + EQE + ++ RR QE QA+
Sbjct: 681 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734
Score = 34.3 bits (77), Expect = 0.14
Identities = 35/178 (19%), Positives = 81/178 (45%), Gaps = 7/178 (3%)
Query: 133 IDTPKEEEFRE-EPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIR 191
++ KEE+ ++ E K ++++K + K M E + E R
Sbjct: 588 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 647
Query: 192 PQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKE----EE 247
+ L + R+ + L ++ Q+R L + E+ +R+Q +++E E
Sbjct: 648 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQER 707
Query: 248 AQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
++++ + E +L +++++ EQ L+ ++ +E+E A K + L+R +E + +E
Sbjct: 708 REQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQ--LQRELEEKKKKEE 763
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 42.7 bits (99), Expect = 4e-04
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 7/96 (7%)
Query: 193 QKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKK- 251
++L + R Q+ + Q+R + + E Q ++R+R+Q Q E E Q++
Sbjct: 678 KRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQERE 737
Query: 252 ------KSDLEIELLKRQQKLEQLELEKQKLQEEQE 281
K L+ EL ++++K EQ L +++LQEEQE
Sbjct: 738 KALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE 773
Score = 38.9 bits (89), Expect = 0.006
Identities = 37/174 (21%), Positives = 80/174 (45%), Gaps = 19/174 (10%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
+EE R+ + E ++M + + I+ K + + ++ A+ + + ++ + K +
Sbjct: 570 REERLRKVLQARERVEQMKEEKKKQ-IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 628
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLE 256
V+ R ++ R L Q Q+ E+R ++ + K+KEEE ++ + E
Sbjct: 629 EEVEARRKQEEEARRLRWLQ------------QEEEERRHQELLQKKKEEEQERLRKAAE 676
Query: 257 IELLKRQQKLEQLELEKQKLQ------EEQENAPEFVKVKGNLRRTGQEVAQAQ 304
+ L Q++ E+ E E+++ + EQE + ++ RR QE QA+
Sbjct: 677 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
Score = 36.2 bits (82), Expect = 0.037
Identities = 58/275 (21%), Positives = 106/275 (38%), Gaps = 41/275 (14%)
Query: 52 VRVQPVAKAGRQPRHPSAEGAPEKRQDSSTHAERNGS----------ANRNSSHRTAAQP 101
+ V+ K G + + P E P + E NG+ AN + + AA
Sbjct: 363 LNVEVPQKVGSEQKEPPEEAEPVAAAEPEV-PENNGNNSWPHNDTEIANSTPNPKPAASS 421
Query: 102 AETPEDVPGSLDDGADCEAVVFHASIPRPSIIDTPKEEEFREEPKCLELEQKMTSDS--P 159
ETP EA A PR ++ +++ L+ EQ + + P
Sbjct: 422 PETPS--------AGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQP 473
Query: 160 PEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRG 219
P ++ + ++ + R Q L+ P TS + + N
Sbjct: 474 PRSKTPSSPCPASKVVRPLRTFLHT----VQRNQMLMTP--TSAPRSVMKSFIKRNTPLR 527
Query: 220 LAPQNKPE--LQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKL----------E 267
+ P+ K L+ + K + +Q+ +QK EE ++++ LE LKR+++L E
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRR--LEEVKLKREERLRKVLQARERVE 585
Query: 268 QLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQ 302
Q++ EK+K E++ + K R +E A+
Sbjct: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 620
Score = 34.3 bits (77), Expect = 0.14
Identities = 35/178 (19%), Positives = 81/178 (45%), Gaps = 7/178 (3%)
Query: 133 IDTPKEEEFRE-EPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIR 191
++ KEE+ ++ E K ++++K + K M E + E R
Sbjct: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
Query: 192 PQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKE----EE 247
+ L + R+ + L ++ Q+R L + E+ +R+Q +++E E
Sbjct: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQER 703
Query: 248 AQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
++++ + E +L +++++ EQ L+ ++ +E+E A K + L+R +E + +E
Sbjct: 704 REQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQ--LQRELEEKKKKEE 759
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 42.7 bits (99), Expect = 4e-04
Identities = 60/256 (23%), Positives = 101/256 (39%), Gaps = 25/256 (9%)
Query: 67 PSAEGAPEKRQDSSTHAERNGSANRNSSHRTAAQ------------PAETPEDVPGSLDD 114
PSA G +K Q + SA S + A PAETP D
Sbjct: 518 PSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSP 577
Query: 115 GADCEAVVFHASIPRPSIIDTPKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRS 174
A V S P D + E + EQ+ + +D +
Sbjct: 578 PAPAPPVT--PSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQ 635
Query: 175 IMAEPDYIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEK 234
+ E + + E R ++ K ++ +E L QK +++ E ++ ++
Sbjct: 636 LAREAEARAEREAEARRREEQEAREKAQAEQEE--QERLQKQKEEAEARSREEAER--QR 691
Query: 235 RKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENA----PEFVK-V 289
+R++ +Q+E+E Q+++ LE E++KR +K E E KQK ++ NA PE VK V
Sbjct: 692 LEREKHFQQQEQERQERRKRLE-EIMKRTRKSEVSE-TKQKQDSKEANANGSSPEPVKAV 749
Query: 290 KGNLRRTGQEVAQAQE 305
+ +E Q +E
Sbjct: 750 EARSPGLQKEAVQKEE 765
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 42.4 bits (98), Expect = 5e-04
Identities = 42/169 (24%), Positives = 77/169 (45%), Gaps = 6/169 (3%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
KEEE +E L E+K ++ ++ + +A+ + + E + K
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLE 256
P + R + RE L+ +K LA + + + + E K ++ QK+ AQ+KK +L
Sbjct: 1791 MPEEEERLGRK--REQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKK-NLA 1847
Query: 257 IELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQE 305
E K Q+ E L K++L ++ + V+VK L + +AQ +E
Sbjct: 1848 QEKEKLAQRKENLLYNKERLTHSKK---QLVQVKNKLGMFNKILAQVEE 1893
Score = 36.2 bits (82), Expect = 0.037
Identities = 25/82 (30%), Positives = 47/82 (57%), Gaps = 6/82 (7%)
Query: 223 QNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQEN 282
Q E Q+ +++ + I +K A+KK++ E +L + ++KL Q E+Q QEE++
Sbjct: 1559 QQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQ--EERQLAQEERKL 1616
Query: 283 APEFVKVKGNLRRTGQEVAQAQ 304
A +VK+ + +E+AQA+
Sbjct: 1617 AQAYVKI----TQDDREMAQAE 1634
Score = 36.2 bits (82), Expect = 0.037
Identities = 44/169 (26%), Positives = 80/169 (47%), Gaps = 11/169 (6%)
Query: 137 KEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLI 196
K E+ E+ L +++ +S E +K +++ E + + +L + ++ +
Sbjct: 1801 KREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENL 1860
Query: 197 NPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEK--RKRDQVIKQKEE--EAQKKK 252
K H ++ L+ K L NK L +V EK ++++ VIK+KE+ E +KK
Sbjct: 1861 LYNKERLTHS---KKQLVQVKNKLGMFNKI-LAQVEEKLTQEKETVIKKKEKLAETEKKL 1916
Query: 253 SDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVA 301
+E L K+Q+KL Q EK KL E+ +++G L +E A
Sbjct: 1917 VQVEDSLAKKQEKLAQ---EKMKLALEKAMVQGKKRLRGELDIAKEEKA 1962
Score = 34.3 bits (77), Expect = 0.14
Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Query: 200 KTSRNHQDLHRELLMNQKRG--LAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEI 257
K ++ + + RE K+G LA QKV E +R+Q + +E+E ++ +LE
Sbjct: 1664 KLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEW 1723
Query: 258 ELLKRQQKLEQLELEKQKLQEEQENAPE 285
++ + K E+L E+ KL EE++ E
Sbjct: 1724 DMEELSWKEEELNQEEGKLVEEKKKLAE 1751
Score = 33.1 bits (74), Expect = 0.32
Identities = 15/88 (17%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Query: 196 INPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKK--S 253
++ V++ + + LL ++ + ++ E ++ E+ + ++ ++++EEE ++++
Sbjct: 2217 VDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276
Query: 254 DLEIELLKRQQKLEQLELEKQKLQEEQE 281
+ ++E + ++K ++ E +K+++QE++E
Sbjct: 2277 EKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304
Score = 32.3 bits (72), Expect = 0.54
Identities = 38/173 (21%), Positives = 71/173 (41%), Gaps = 17/173 (9%)
Query: 138 EEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSIMAEPDYIEDDNPELIRPQKLIN 197
EEE E + E EQ++T + +HK + + + AE +++ +KL
Sbjct: 1547 EEEVSREGE--EKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQ 1604
Query: 198 PVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEI 257
+ L ++R LA Q E + + QKEE ++ L
Sbjct: 1605 EERQ-----------LAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQ 1653
Query: 258 ELLKRQQKLEQLELEKQKLQEEQE----NAPEFVKVKGNLRRTGQEVAQAQES 306
E K QK ++L + +K+ E+E + +VK L + +E+ Q +++
Sbjct: 1654 EAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQN 1706
Score = 32.0 bits (71), Expect = 0.70
Identities = 17/79 (21%), Positives = 46/79 (58%), Gaps = 3/79 (3%)
Query: 227 ELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEF 286
E++ ++++ ++ + + +EEE ++++ + E E ++ +++ + E E ++ Q E+E E
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKE---EE 2285
Query: 287 VKVKGNLRRTGQEVAQAQE 305
K K + +EV + +E
Sbjct: 2286 EKKKKKKEKKKEEVQEKEE 2304
Score = 31.6 bits (70), Expect = 0.92
Identities = 17/59 (28%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
Query: 223 QNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQE 281
+ + E +K E+ + QV K++EE+ +KKK + E+ ++++ E EK+++ E+E
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE----EKEEIMSEEE 2317
Score = 29.6 bits (65), Expect = 3.5
Identities = 20/70 (28%), Positives = 36/70 (51%)
Query: 211 ELLMNQKRGLAPQNKPELQKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLE 270
E L +++ L Q K Q++ E + + KEEE +++ L E K ++ E L
Sbjct: 1698 EELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALA 1757
Query: 271 LEKQKLQEEQ 280
+++KL EE+
Sbjct: 1758 WQREKLSEEE 1767
Score = 28.9 bits (63), Expect = 6.0
Identities = 24/110 (21%), Positives = 54/110 (49%), Gaps = 9/110 (8%)
Query: 188 ELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEK----RKRDQVIKQ 243
EL + + L + + R ++ E + ++ + + +K +EK +K+ + K+
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Query: 244 KEEEAQKKKSDLEIELLKRQQKLEQLELEKQK-----LQEEQENAPEFVK 288
KEE +K++ E E + +++ E L E+++ L+EE + E +K
Sbjct: 2296 KEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILK 2345
>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
Length = 1123
Score = 42.4 bits (98), Expect = 5e-04
Identities = 29/95 (30%), Positives = 55/95 (57%), Gaps = 7/95 (7%)
Query: 190 IRPQKLINPVKTSRNHQDLHRELLM----NQKRGLAPQNKPELQKVMEKRKRDQVIKQKE 245
+R Q+L + + Q L ++LL Q L Q++ +LQK +++++ KQ++
Sbjct: 72 LREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQ 131
Query: 246 EE-AQKKKSDLEIELLKRQQKLEQLELEKQKLQEE 279
E A K++ +LE + + QQ+ E ELEKQ+L+++
Sbjct: 132 EMLAAKRQQELEQQRQREQQRQE--ELEKQRLEQQ 164
Score = 29.3 bits (64), Expect = 4.6
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 209 HRELLMNQKRGLAPQNKPELQKVMEKRKRDQVI-KQKEEEAQKKKSDLEIELLKRQQKLE 267
HR L Q L PQ+ LQ+++ +++ Q + KQK+++ Q K + L RQ
Sbjct: 491 HRPLSRTQSSPL-PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTH 549
Query: 268 QLELEKQKLQEEQE 281
E E ++L E+QE
Sbjct: 550 PEETE-EELTEQQE 562
>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
Length = 1122
Score = 42.4 bits (98), Expect = 5e-04
Identities = 29/95 (30%), Positives = 55/95 (57%), Gaps = 7/95 (7%)
Query: 190 IRPQKLINPVKTSRNHQDLHRELLM----NQKRGLAPQNKPELQKVMEKRKRDQVIKQKE 245
+R Q+L + + Q L ++LL Q L Q++ +LQK +++++ KQ++
Sbjct: 71 LREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQ 130
Query: 246 EE-AQKKKSDLEIELLKRQQKLEQLELEKQKLQEE 279
E A K++ +LE + + QQ+ E ELEKQ+L+++
Sbjct: 131 EMLAAKRQQELEQQRQREQQRQE--ELEKQRLEQQ 163
Score = 29.3 bits (64), Expect = 4.6
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 209 HRELLMNQKRGLAPQNKPELQKVMEKRKRDQVI-KQKEEEAQKKKSDLEIELLKRQQKLE 267
HR L Q L PQ+ LQ+++ +++ Q + KQK+++ Q K + L RQ
Sbjct: 490 HRPLSRTQSSPL-PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTH 548
Query: 268 QLELEKQKLQEEQE 281
E E ++L E+QE
Sbjct: 549 PEETE-EELTEQQE 561
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 42.0 bits (97), Expect = 7e-04
Identities = 28/123 (22%), Positives = 61/123 (49%), Gaps = 11/123 (8%)
Query: 181 YIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQV 240
Y+ P+ I Q++ + ++ + L R L N+K+ +++ EK K +
Sbjct: 291 YMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKK---------KREIAEKEK--ER 339
Query: 241 IKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEV 300
I++++EE ++ +E + +K Q++LE+ + +L +E++ A E + RR +E
Sbjct: 340 IEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEA 399
Query: 301 AQA 303
A
Sbjct: 400 KSA 402
Score = 32.3 bits (72), Expect = 0.54
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
Query: 178 EPDYIEDDNPELIRPQKLINP--VKTSRNHQDLHRELL-MNQKRGLAPQNKPELQKVMEK 234
E + IE + EL+ K I +K + ++ R+ L ++Q+R A + L+K E+
Sbjct: 336 EKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEK--ER 393
Query: 235 RKRDQV---IKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEE 279
R ++ I ++ + K + L EL + K+ LE K+K +EE
Sbjct: 394 RAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEE 441
Score = 32.0 bits (71), Expect = 0.70
Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 229 QKVMEKRKRDQVIKQKEEEAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVK 288
QK +E+ + + K+K E A+K+K +E E + ++L+Q+E + K Q+E E
Sbjct: 315 QKQLERAQLENE-KKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKAL 373
Query: 289 VKGNLRRTGQEVAQAQE 305
R+ +E A+ E
Sbjct: 374 ELDQERKRAKEEAERLE 390
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 41.6 bits (96), Expect = 9e-04
Identities = 31/135 (22%), Positives = 67/135 (49%), Gaps = 20/135 (14%)
Query: 181 YIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQV 240
Y+ P+ I Q++ + ++ + L R+ L +K+ ++ +R+++Q+
Sbjct: 291 YMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKK----------RRETVEREKEQM 340
Query: 241 IKQKEE------EAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQE----NAPEFVKVK 290
+++KEE + ++K E EL ++ Q+ QLE E+++ QEE E + ++ K
Sbjct: 341 MREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAK 400
Query: 291 GNLRRTGQEVAQAQE 305
L R + ++QE
Sbjct: 401 EELERQAVDQIKSQE 415
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 41.6 bits (96), Expect = 9e-04
Identities = 31/135 (22%), Positives = 67/135 (49%), Gaps = 20/135 (14%)
Query: 181 YIEDDNPELIRPQKLINPVKTSRNHQDLHRELLMNQKRGLAPQNKPELQKVMEKRKRDQV 240
Y+ P+ I Q++ + ++ + L R+ L +K+ ++ +R+++Q+
Sbjct: 291 YMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKK----------RRETVEREKEQM 340
Query: 241 IKQKEE------EAQKKKSDLEIELLKRQQKLEQLELEKQKLQEEQE----NAPEFVKVK 290
+++KEE + ++K E EL ++ Q+ QLE E+++ QEE E + ++ K
Sbjct: 341 MREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAK 400
Query: 291 GNLRRTGQEVAQAQE 305
L R + ++QE
Sbjct: 401 EELERQAVDQIKSQE 415
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 41.6 bits (96), Expect = 9e-04
Identities = 44/233 (18%), Positives = 104/233 (44%), Gaps = 26/233 (11%)
Query: 77 QDSSTHAERNGSANRNSSHRTAAQPAETPEDVPGSLDDGADCEAV-VFHASIPRPSIIDT 135
Q+S+T N S N+N ++Q D S D ++ V + H
Sbjct: 3 QESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHL---------- 52
Query: 136 PKEEEFREEPKCLELEQKMTSDSPPEDIDHKDSYLITRSI-MAEPDYIEDDNPELIRPQK 194
++++ + + L L+Q+ + P+ D + + S+ M P I + I Q+
Sbjct: 53 -QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQ 111
Query: 195 LINPVKTSRNHQDLHRELLMNQKRG---LAPQNKPELQKVMEKRKRDQVIKQKEEEAQKK 251
+++P + Q +L Q+ Q + LQ + +++++ Q +Q++++ Q+
Sbjct: 112 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ- 170
Query: 252 KSDLEIELLKRQQKLEQLELEKQKLQEEQENAPEFVKVKGNLRRTGQEVAQAQ 304
++QQ+ +Q + ++Q+ Q++Q++ + K + ++ Q++A Q
Sbjct: 171 ---------QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,352,984
Number of Sequences: 37866
Number of extensions: 714478
Number of successful extensions: 10841
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 332
Number of HSP's successfully gapped in prelim test: 681
Number of HSP's that attempted gapping in prelim test: 5477
Number of HSP's gapped (non-prelim): 4014
length of query: 306
length of database: 18,247,518
effective HSP length: 102
effective length of query: 204
effective length of database: 14,385,186
effective search space: 2934577944
effective search space used: 2934577944
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.