Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 40217847
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40217847 activating signal cointegrator 1 complex subunit
3-like 1 [Homo sapiens]
(2136 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40217847 activating signal cointegrator 1 complex subunit 3-l... 4251 0.0
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote... 3351 0.0
gi|76880486 activating signal cointegrator 1 complex subunit 3 i... 1532 0.0
gi|239756904 PREDICTED: similar to SNRNP200 protein [Homo sapiens] 498 e-140
gi|239745928 PREDICTED: hypothetical protein XP_002343618 [Homo ... 437 e-122
gi|130484567 HFM1 protein [Homo sapiens] 323 1e-87
gi|139394648 DNA polymerase theta [Homo sapiens] 136 2e-31
gi|110556640 DNA helicase HEL308 [Homo sapiens] 130 1e-29
gi|67782311 superkiller viralicidic activity 2-like homolog [Hom... 112 4e-24
gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sap... 96 3e-19
gi|6005872 SEC63-like protein [Homo sapiens] 74 1e-12
gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sap... 65 5e-10
gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Hom... 58 1e-07
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 47 2e-04
gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens] 45 6e-04
gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens] 45 6e-04
gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens] 45 6e-04
gi|27886568 interferon induced with helicase C domain 1 [Homo sa... 44 0.002
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 44 0.002
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 44 0.002
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi... 44 0.002
gi|29294649 dicer1 [Homo sapiens] 42 0.008
gi|29294651 dicer1 [Homo sapiens] 42 0.008
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 40 0.019
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 40 0.024
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 40 0.024
gi|149408122 RNA helicase LGP2 [Homo sapiens] 40 0.032
gi|18093112 ABT1-associated protein [Homo sapiens] 40 0.032
gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I [... 39 0.042
gi|74959747 Fanconi anemia, complementation group M [Homo sapiens] 39 0.042
>gi|40217847 activating signal cointegrator 1 complex subunit 3-like 1
[Homo sapiens]
Length = 2136
Score = 4251 bits (11024), Expect = 0.0
Identities = 2136/2136 (100%), Positives = 2136/2136 (100%)
Query: 1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTK 60
MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTK
Sbjct: 1 MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTK 60
Query: 61 PQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFI 120
PQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFI
Sbjct: 61 PQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFI 120
Query: 121 QAALGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDDTRYHVLVNLGKKIT 180
QAALGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDDTRYHVLVNLGKKIT
Sbjct: 121 QAALGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDDTRYHVLVNLGKKIT 180
Query: 181 DYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTL 240
DYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTL
Sbjct: 181 DYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTL 240
Query: 241 SANLVASGELMSSKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDR 300
SANLVASGELMSSKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDR
Sbjct: 241 SANLVASGELMSSKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDR 300
Query: 301 ECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFL 360
ECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFL
Sbjct: 301 ECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFL 360
Query: 361 YQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGS 420
YQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGS
Sbjct: 361 YQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGS 420
Query: 421 HFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKT 480
HFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKT
Sbjct: 421 HFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKT 480
Query: 481 LNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIY 540
LNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIY
Sbjct: 481 LNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIY 540
Query: 541 IAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKG 600
IAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKG
Sbjct: 541 IAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKG 600
Query: 601 GERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYED 660
GERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYED
Sbjct: 601 GERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYED 660
Query: 661 VATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQ 720
VATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQ
Sbjct: 661 VATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQ 720
Query: 721 VLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPY 780
VLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPY
Sbjct: 721 VLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPY 780
Query: 781 GFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGR 840
GFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGR
Sbjct: 781 GFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGR 840
Query: 841 WTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDM 900
WTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDM
Sbjct: 841 WTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDM 900
Query: 901 LNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTA 960
LNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTA
Sbjct: 901 LNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTA 960
Query: 961 ALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSL 1020
ALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSL
Sbjct: 961 ALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSL 1020
Query: 1021 SSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMAD 1080
SSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMAD
Sbjct: 1021 SSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMAD 1080
Query: 1081 MVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVV 1140
MVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVV
Sbjct: 1081 MVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVV 1140
Query: 1141 KKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKV 1200
KKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKV
Sbjct: 1141 KKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKV 1200
Query: 1201 ELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFE 1260
ELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFE
Sbjct: 1201 ELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFE 1260
Query: 1261 PLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESL 1320
PLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESL
Sbjct: 1261 PLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESL 1320
Query: 1321 YQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYIT 1380
YQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYIT
Sbjct: 1321 YQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYIT 1380
Query: 1381 PMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWK 1440
PMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWK
Sbjct: 1381 PMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWK 1440
Query: 1441 QRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDV 1500
QRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDV
Sbjct: 1441 QRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDV 1500
Query: 1501 AHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVI 1560
AHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVI
Sbjct: 1501 AHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVI 1560
Query: 1561 VFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYL 1620
VFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYL
Sbjct: 1561 VFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYL 1620
Query: 1621 HEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYP 1680
HEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYP
Sbjct: 1621 HEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYP 1680
Query: 1681 IYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEI 1740
IYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEI
Sbjct: 1681 IYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEI 1740
Query: 1741 VTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSK 1800
VTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSK
Sbjct: 1741 VTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSK 1800
Query: 1801 CISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPI 1860
CISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPI
Sbjct: 1801 CISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPI 1860
Query: 1861 RHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAI 1920
RHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAI
Sbjct: 1861 RHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAI 1920
Query: 1921 RLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVE 1980
RLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVE
Sbjct: 1921 RLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVE 1980
Query: 1981 SVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQ 2040
SVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQ
Sbjct: 1981 SVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQ 2040
Query: 2041 LEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATG 2100
LEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATG
Sbjct: 2041 LEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATG 2100
Query: 2101 AHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD 2136
AHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD
Sbjct: 2101 AHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD 2136
>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
partial [Homo sapiens]
Length = 1700
Score = 3351 bits (8690), Expect = 0.0
Identities = 1679/1700 (98%), Positives = 1686/1700 (99%)
Query: 437 RQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETD 496
RQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETD
Sbjct: 1 RQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETD 60
Query: 497 ENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFG 556
ENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFG
Sbjct: 61 ENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFG 120
Query: 557 KRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDE 616
KRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLI+LDE
Sbjct: 121 KRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDE 180
Query: 617 IHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYF 676
IHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYF
Sbjct: 181 IHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYF 240
Query: 677 DNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTAR 736
DNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTAR
Sbjct: 241 DNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTAR 300
Query: 737 AIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTL 796
AIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTL
Sbjct: 301 AIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTL 360
Query: 797 VEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRA 856
VEDLF DKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRA
Sbjct: 361 VEDLFGDKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRA 420
Query: 857 GRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDA 916
GRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDA
Sbjct: 421 GRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDA 480
Query: 917 VNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKT 976
VNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKT
Sbjct: 481 VNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKT 540
Query: 977 GNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLE 1036
GNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLE
Sbjct: 541 GNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLE 600
Query: 1037 LQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIF 1096
LQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIF
Sbjct: 601 LQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIF 660
Query: 1097 EIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDL 1156
EIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDL
Sbjct: 661 EIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDL 720
Query: 1157 NHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHG 1216
NHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHG
Sbjct: 721 NHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHG 780
Query: 1217 SSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWL 1276
SSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWL
Sbjct: 781 SSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWL 840
Query: 1277 SCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVF 1336
SCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVF
Sbjct: 841 SCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVF 900
Query: 1337 NTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEK 1396
NTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQ+SEGRCVYITPM EQVYMDWYEK
Sbjct: 901 NTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMRLWQEQVYMDWYEK 960
Query: 1397 FQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEV 1456
FQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEV
Sbjct: 961 FQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEV 1020
Query: 1457 HLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHP 1516
HLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHP
Sbjct: 1021 HLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHP 1080
Query: 1517 NVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDI 1576
NVRPVPLELHIQGFNISHTQTRLLSMAKPV+HAITKHSPKKPVIVFVPSRKQTRLTAIDI
Sbjct: 1081 NVRPVPLELHIQGFNISHTQTRLLSMAKPVFHAITKHSPKKPVIVFVPSRKQTRLTAIDI 1140
Query: 1577 LTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLF 1636
LTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLF
Sbjct: 1141 LTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLF 1200
Query: 1637 SSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQ 1696
SSGAIQVVVASRSLCWGMNVAAHLVIIMDT YYNGKIHAYVDYPIYDVLQMVGHANRPLQ
Sbjct: 1201 SSGAIQVVVASRSLCWGMNVAAHLVIIMDTLYYNGKIHAYVDYPIYDVLQMVGHANRPLQ 1260
Query: 1697 DDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLT 1756
DDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLT
Sbjct: 1261 DDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLT 1320
Query: 1757 WTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLG 1816
WTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLG
Sbjct: 1321 WTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLG 1380
Query: 1817 MIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVP 1876
MIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVP
Sbjct: 1381 MIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVP 1440
Query: 1877 HKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWL 1936
HKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWL
Sbjct: 1441 HKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWL 1500
Query: 1937 SPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNAL 1996
SPALAAMELAQMVTQAMWS+DSYL++LP F S KRCTDKGVESVFDIMEMEDEERNAL
Sbjct: 1501 SPALAAMELAQMVTQAMWSEDSYLRRLPPFPSGLFKRCTDKGVESVFDIMEMEDEERNAL 1560
Query: 1997 LQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLF 2056
LQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLF
Sbjct: 1561 LQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLF 1620
Query: 2057 PQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGC 2116
PQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATG + TLYFMSDAYMGC
Sbjct: 1621 PQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATGGRHNTLYFMSDAYMGC 1680
Query: 2117 DQEYKFSVDVKEAETDSDSD 2136
DQEYKFSVDVKEAETDSDSD
Sbjct: 1681 DQEYKFSVDVKEAETDSDSD 1700
>gi|76880486 activating signal cointegrator 1 complex subunit 3
isoform a [Homo sapiens]
Length = 2202
Score = 1532 bits (3966), Expect = 0.0
Identities = 816/1933 (42%), Positives = 1207/1933 (62%), Gaps = 97/1933 (5%)
Query: 291 EILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEK-----ER 345
++L + E +++L LLG + I+ L Q+R+ I+ L +S + ++
Sbjct: 253 DMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQDNCKK 312
Query: 346 IMGK---------MEADPELSKFLYQLHETEKEDLIREERSRRE--RVRQSRMDTDLETM 394
I+G+ + E K L + + E++ + R E+ E V + M D + +
Sbjct: 313 ILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEVSEGLMCFDPKEL 372
Query: 395 DLDQGGEALAPRQV--------LDLEDLVFT----------QGSHFMANKRCQLPDGSFR 436
+ + L R V D+E + + + S F+A + LP+G R
Sbjct: 373 RIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPEGIQR 432
Query: 437 RQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETD 496
K YEEV +P +P P EE+ + ++ L + Q F+G K LNRIQS ++ A T+
Sbjct: 433 ENNKLYEEVRIPYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETAYNTN 492
Query: 497 ENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFG 556
EN+L+CAPTGAGKTN+A++ +L EI +H G I ++FKI+Y+APM++L EM F
Sbjct: 493 ENMLICAPTGAGKTNIAMLTVLHEIRQHFQQ-GVIKKNEFKIVYVAPMKALAAEMTDYFS 551
Query: 557 KRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKG-GERTYTQLVRLIILD 615
+RL GI V ELTGD QL K EI TQ++V TPEKWD++TRK G+ +Q+VRL+ILD
Sbjct: 552 RRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILD 611
Query: 616 EIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFY 675
E+HLLH+DRGPVLE++VAR +R +E TQ +R++GLSATLPNY DVATFL V+P GLF+
Sbjct: 612 EVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFF 671
Query: 676 FDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHA-GKNQVLVFVHSRKETGKT 734
FD FRPVPL QT++GI +++ M+E+ YE +++ +QV+VFVH+R T +T
Sbjct: 672 FDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNATVRT 731
Query: 735 ARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDR 794
A ++ + + F + + ++ +N ++++L P GF+IHHAGM R DR
Sbjct: 732 AMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDR 791
Query: 795 TLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLG 854
LVE+LF++ HI+VLV TATLAWGVNLPAH VIIKGTQ+Y+ ++G + +LG LD++Q+ G
Sbjct: 792 NLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFG 851
Query: 855 RAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAK 914
RAGRPQ+D GEGI+IT+H +L +YL+LL Q+ PIESQ + L D LNAEI LG V N +
Sbjct: 852 RAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVTNVE 911
Query: 915 DAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDK 974
+AV W+ Y YLY+RM +P YGISH + DP L + R LV LDK ++++++
Sbjct: 912 EAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEE 971
Query: 975 KTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEK 1034
+TG F T+LGR ASHYYI +T++T+N+L +E ++F + S + EF I VREEE
Sbjct: 972 RTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEI 1031
Query: 1035 LELQKLLERV-PIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMR 1093
EL LL + +E KIN+LLQ +IS+ +++ F+L++D YV Q+A R++R
Sbjct: 1032 EELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVR 1091
Query: 1094 AIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERL 1153
A+FEI L + W +T + LNL K+IDKR+W PLRQF LP ++ ++E+K ++L
Sbjct: 1092 ALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKL 1151
Query: 1154 YDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEK 1213
D+ +EIG ++ +G + + VH P + + +QPITR+ L+V L+I DF W+++
Sbjct: 1152 KDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQ 1211
Query: 1214 VHGS-SEAFWILVEDVDSEVILHHEYFLLKAKY--AQDEHLITFFVPVFEPLPPQYFIRV 1270
VHG+ E +WI VED ++ I H EYFL K +++ L+ F +P+FEPLP QY+IR
Sbjct: 1212 VHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYYIRA 1271
Query: 1271 VSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNP 1330
VSDRWL E ++F+HLILPE++PP TELLDLQPLP++AL A+E+LY F FNP
Sbjct: 1272 VSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYN--FSHFNP 1329
Query: 1331 IQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVY 1390
+QTQ+F+T+Y++D NV +GAPTGSGKT+ AE AI R+ + + VYI P++AL +
Sbjct: 1330 VQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERM 1389
Query: 1391 MDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINL 1450
DW + +++L KKV+ LTG+ + D+K + K ++I++TPEKWD +SR W+ R VQ + +
Sbjct: 1390 DDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTI 1449
Query: 1451 FVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATS 1510
++DE+HL+G E GPVLEVI SR +ISS E+P+RIV LS++L+NA+D+A WL
Sbjct: 1450 LIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMG 1509
Query: 1511 TFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTR 1570
FNF P+VRPVPLE+HIQGF H R+ SM KP + AI HSP KPV++FV SR+QTR
Sbjct: 1510 LFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTR 1569
Query: 1571 LTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERR 1630
LTA++++ A + +++L+ E+++ + + DS LK TL G+G H GL +R+
Sbjct: 1570 LTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRK 1629
Query: 1631 LVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGH 1690
VE+LF + +QV++A+ +L WG+N AHLVII T+YY+GK YVD+PI DVLQM+G
Sbjct: 1630 TVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGR 1689
Query: 1691 ANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQD 1750
A RP DD+G+ VI+ KKDF+KKFLYEP PVES L + DH NAEI TI +KQD
Sbjct: 1690 AGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQD 1749
Query: 1751 AVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISI-EDEMD 1809
A+DY+TWT+ +RR+ NP+YYNL +SH ++ LS L+E++L +LE S CI I ED
Sbjct: 1750 ALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRS 1809
Query: 1810 VAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLR 1869
+ PL G IA+YYY+ + T+++F L + L+ I+S+A EY ++P+RH+ED++
Sbjct: 1810 IEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMNS 1869
Query: 1870 QLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSA-ELQSDTEEILSKAIRLIQACVD 1928
+LA+ +P + N F+ PH K +LLLQAHLSR L + +DT+ +L +A+R+ QA +D
Sbjct: 1870 ELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLD 1929
Query: 1929 VLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHI----------KRCTDKG 1978
V ++ GWL L L QMV Q W KDS L LP+ + H+ K +G
Sbjct: 1930 VAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHARG 1989
Query: 1979 VESVFDIMEM------EDEERNALL--QLTDSQIADVARFCNRYPNI------------- 2017
S+ + E+ +D ++++ +L ++ F + P I
Sbjct: 1990 RTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDDL 2049
Query: 2018 -----ELSYEVVDKD--------SIRSGGPVVVLVQLER------EEEVTGPVIAPLFPQ 2058
ELS + D + + V+ V L+R + + + P FP+
Sbjct: 2050 VEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFPK 2109
Query: 2059 KREEGWWVVIGDAKSNSLISIKRL-TLQQKAKVKLDFVAP-ATGAHNYTLYFMSDAYMGC 2116
++EGW++++G+ LI++KR+ ++ L F P G + YTLYFMSD Y+G
Sbjct: 2110 SKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLGL 2169
Query: 2117 DQEYKFSVDVKEA 2129
DQ+Y ++V +A
Sbjct: 2170 DQQYDIYLNVTQA 2182
>gi|239756904 PREDICTED: similar to SNRNP200 protein [Homo sapiens]
Length = 302
Score = 498 bits (1283), Expect = e-140
Identities = 256/311 (82%), Positives = 269/311 (86%), Gaps = 18/311 (5%)
Query: 1826 YTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNPKFN 1885
+ ++ F S+ T+V E A YENIPI+HHE+N LRQLAQKVP KLNNPKFN
Sbjct: 10 FLKLKTFGFSIQEGTRVG---ERKRGATGYENIPIQHHEENFLRQLAQKVPDKLNNPKFN 66
Query: 1886 DPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMEL 1945
DPH+KTNLLLQAHLSRMQLSAELQSDTEEILSKA+RL+QACVDVLSSNGWLS ALAAMEL
Sbjct: 67 DPHIKTNLLLQAHLSRMQLSAELQSDTEEILSKAVRLVQACVDVLSSNGWLSSALAAMEL 126
Query: 1946 AQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIA 2005
AQMVTQAMWSKDSYLKQLPHF SEHIKRCTDKGV+SVFDIMEMEDEERN +LQLTDSQI
Sbjct: 127 AQMVTQAMWSKDSYLKQLPHFISEHIKRCTDKGVKSVFDIMEMEDEERNTILQLTDSQIT 186
Query: 2006 DVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWW 2065
D EVVDKDSIRSGGP VVLVQLEREEEVTGPVIAPLFPQKREEGWW
Sbjct: 187 D---------------EVVDKDSIRSGGPAVVLVQLEREEEVTGPVIAPLFPQKREEGWW 231
Query: 2066 VVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFSVD 2125
VVIGD KSNSLISIKRL LQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFS+D
Sbjct: 232 VVIGDTKSNSLISIKRLILQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFSMD 291
Query: 2126 VKEAETDSDSD 2136
VKEAETDSDSD
Sbjct: 292 VKEAETDSDSD 302
Score = 61.6 bits (148), Expect = 8e-09
Identities = 61/269 (22%), Positives = 113/269 (42%), Gaps = 22/269 (8%)
Query: 1024 FKNITVREEEKLELQKLLERVPIPVKE-SIEEPSAKINVLLQAFISQLKLEGFALMADMV 1082
++NI ++ E+ L++L ++VP + +P K N+LLQA +S+++L L +D
Sbjct: 36 YENIPIQHHEENFLRQLAQKVPDKLNNPKFNDPHIKTNLLLQAHLSRMQLSA-ELQSDTE 94
Query: 1083 YVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKK 1142
+ A RL++A +++ + GW + L +M+ + MW L+Q E +K+
Sbjct: 95 EILSKAVRLVQACVDVLSSNGWLSSALAAMELAQMVTQAMWSKDSYLKQLPHFISEHIKR 154
Query: 1143 IEKKN----FPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTL 1198
K F + D N I +L + + K +V L + R
Sbjct: 155 CTDKGVKSVFDIMEMEDEERNTILQLTDSQITDEVVDK--DSIRSGGPAVVLVQLEREEE 212
Query: 1199 KVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLL--KAKYAQDEHLITFFV 1256
I P F + E +W+++ D S ++ + +L KAK D F
Sbjct: 213 VTGPVIAPLFPQKRE-----EGWWVVIGDTKSNSLISIKRLILQQKAKVKLD-----FVA 262
Query: 1257 PVFEPLPPQYFIRVVSDRWLSCETQLPVS 1285
P Y + +SD ++ C+ + S
Sbjct: 263 PATG--AHNYTLYFMSDAYMGCDQEYKFS 289
>gi|239745928 PREDICTED: hypothetical protein XP_002343618 [Homo
sapiens]
Length = 299
Score = 437 bits (1124), Expect = e-122
Identities = 228/298 (76%), Positives = 237/298 (79%), Gaps = 52/298 (17%)
Query: 1839 KTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAH 1898
+TKVRGLIEIISNAA YENIPI+HHE+N LRQLAQKVP KLNNPKFNDPH+KTNLLLQAH
Sbjct: 54 RTKVRGLIEIISNAAGYENIPIQHHEENFLRQLAQKVPDKLNNPKFNDPHIKTNLLLQAH 113
Query: 1899 LSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDS 1958
LSRMQLSAELQSDTEEILSKA+RL+QACVDVLSSNGWLS ALAAMELAQMVTQAMWSKDS
Sbjct: 114 LSRMQLSAELQSDTEEILSKAVRLVQACVDVLSSNGWLSSALAAMELAQMVTQAMWSKDS 173
Query: 1959 YLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIE 2018
YLKQLPHF SEHIKRCTDKGV+SVFDIMEMEDEERN +LQLTDSQI D
Sbjct: 174 YLKQLPHFISEHIKRCTDKGVKSVFDIMEMEDEERNTILQLTDSQITD------------ 221
Query: 2019 LSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLIS 2078
KREEGWWVVIGD KSNSLIS
Sbjct: 222 ----------------------------------------KREEGWWVVIGDTKSNSLIS 241
Query: 2079 IKRLTLQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD 2136
IKRL LQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFS+DVKEAETDSDSD
Sbjct: 242 IKRLILQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFSMDVKEAETDSDSD 299
Score = 62.0 bits (149), Expect = 6e-09
Identities = 40/156 (25%), Positives = 76/156 (48%), Gaps = 6/156 (3%)
Query: 1014 LFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKE-SIEEPSAKINVLLQAFISQLKL 1072
L + S ++ ++NI ++ E+ L++L ++VP + +P K N+LLQA +S+++L
Sbjct: 60 LIEIISNAAGYENIPIQHHEENFLRQLAQKVPDKLNNPKFNDPHIKTNLLLQAHLSRMQL 119
Query: 1073 EGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQF 1132
L +D + A RL++A +++ + GW + L +M+ + MW L+Q
Sbjct: 120 SA-ELQSDTEEILSKAVRLVQACVDVLSSNGWLSSALAAMELAQMVTQAMWSKDSYLKQL 178
Query: 1133 RKLPEEVVKKIEKKN----FPFERLYDLNHNEIGEL 1164
E +K+ K F + D N I +L
Sbjct: 179 PHFISEHIKRCTDKGVKSVFDIMEMEDEERNTILQL 214
>gi|130484567 HFM1 protein [Homo sapiens]
Length = 1435
Score = 323 bits (828), Expect = 1e-87
Identities = 267/866 (30%), Positives = 444/866 (51%), Gaps = 67/866 (7%)
Query: 415 VFTQGSHFMANKRCQLPDGSFRRQR--KGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQ 472
VFT + F A+ ++ +G F+ ++ + + GS L V ++P +
Sbjct: 219 VFTANNAFSAS---EIGEGMFKAPSFSVAFQPHDIQEVTENGLGS---LKAVTEIPAKFR 272
Query: 473 AGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTIN 532
+ F+ F N IQSK + L TD N ++CAPTG+GKT V + + R + M+ +
Sbjct: 273 SIFKEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLL-----MEVPLP 327
Query: 533 VDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKE-EISATQIIVCTPE 591
+ KI+Y+AP+++L + + ++ G+ ELTGD + EI II+ TPE
Sbjct: 328 WLNIKIVYMAPIKALCSQRFDDWKEKFGPIGLNCKELTGDTVMDDLFEIQHAHIIMTTPE 387
Query: 592 KWDIITRKGGERTYTQLVRLIILDEIHLLHDD-RGPVLEALVAR--AIRNIEMTQED--- 645
KWD +TRK + + QLVRL ++DE+H++ D+ RGP LE +V+R ++++ T ++
Sbjct: 388 KWDSMTRKWRDNSLVQLVRLFLIDEVHIVKDENRGPTLEVVVSRMKTVQSVSQTLKNTST 447
Query: 646 ---VRLIGLSATLPNYEDVATFLRVDPAKGL-FYFDNSFRPVPLEQTYVGITEKKAIKRF 701
+R + +SAT+PN ED+A +L + D S RPV L++ +G F
Sbjct: 448 AIPMRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSNQTEF 507
Query: 702 QI---MNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSAS 758
+ +N + I ++ + LVF +RK + A L KD + E
Sbjct: 508 KFDLTLNYKIASVIQMYSDQKPTLVFCATRKGVQQAASV-----LVKDAKFIMTVE---Q 559
Query: 759 TEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWG 818
+ L+ A ++ +L+D+L G A HHAGM DR +VE F + VL +T+TLA G
Sbjct: 560 KQRLQKYAYSVRDSKLRDILKDGAAYHHAGMELSDRKVVEGAFTVGDLPVLFTTSTLAMG 619
Query: 819 VNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQY 878
VNLPAH V+IK T Y+ G + E DILQM+GRAGRPQ+DT +++T
Sbjct: 620 VNLPAHLVVIKSTMHYAG--GLFEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTRDK 677
Query: 879 YLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGI 938
Y+ +L + +ES + L + LNAEIVL + + AV W+ LYIR L++P+ YG
Sbjct: 678 YIQMLACRDTVESSLHRHLIEHLNAEIVLHTITDVNIAVEWIRSTLLYIRALKNPSHYGF 737
Query: 939 SHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTV 998
+ K ++ + +L L +L+K D+ NF+ TE GR+ + YYIT +TV
Sbjct: 738 ASGLNKDG--IEAKLQELCLKNLNDLSSLDLIKMDEGV-NFKPTEAGRLMAWYYITFETV 794
Query: 999 QTYNQLL-KPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLE-----RVPIPVKESI 1052
+ + + K TLS +L + + EF +I +R EK L L + + P++ I
Sbjct: 795 KKFYTISGKETLS--DLVTLIAGCKEFLDIQLRINEKKTLNTLNKDPNRITIRFPMEGRI 852
Query: 1053 EEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVL--NRGWAQLTDK 1110
+ K+N L+QA + + ++ FAL D + + R+ R + + V + +A L +
Sbjct: 853 KTREMKVNCLIQAQLGCIPIQDFALTQDTAKIFRHGSRITRWLSDFVAAQEKKFAVLLN- 911
Query: 1111 TLNLCKMIDKRMWQ-SMCPLRQFRKLPEEVVKKIEKKNF-PFERLYDLNHNEIGELI--R 1166
+L L K ++W+ S+ +Q K+ + I F+++ + + E+ ELI R
Sbjct: 912 SLILAKCFRCKLWENSLHVSKQLEKIGITLSNAIVNAGLTSFKKIEETDAREL-ELILNR 970
Query: 1167 MPKMGKTIHKYVHLFPKLELSVHLQPITR---STLKVELT-ITPDFQWDEKVHGSSEAFW 1222
P G I + V PK EL V + ITR +T ++ +T I +F+ + +S++ +
Sbjct: 971 HPPFGTQIKETVMYLPKYELKV--EQITRYSDTTAEILVTVILRNFEQLQTKRTASDSHY 1028
Query: 1223 I--LVEDVDSEVILHH---EYFLLKA 1243
+ ++ D D++V+ H + LLKA
Sbjct: 1029 VTLIIGDADNQVVYLHKITDSVLLKA 1054
Score = 318 bits (816), Expect = 3e-86
Identities = 247/845 (29%), Positives = 421/845 (49%), Gaps = 60/845 (7%)
Query: 1317 FESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSS---- 1372
F S++++ FP+FN IQ++ F+ + +D N + APTGSGKT+ E AI R+L++
Sbjct: 271 FRSIFKE-FPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLLMEVPLPWL 329
Query: 1373 EGRCVYITPMEALAEQVYMDWYEKFQD-RLNKKVVLLTGET-STDLKLLGKGNIIISTPE 1430
+ VY+ P++AL Q + DW EKF LN K LTG+T DL + +II++TPE
Sbjct: 330 NIKIVYMAPIKALCSQRFDDWKEKFGPIGLNCKE--LTGDTVMDDLFEIQHAHIIMTTPE 387
Query: 1431 KWDILSRRWKQRKNVQNINLFVVDEVHLIGGEN-GPVLEVICSRMRYISSQIER------ 1483
KWD ++R+W+ VQ + LF++DEVH++ EN GP LEV+ SRM+ + S +
Sbjct: 388 KWDSMTRKWRDNSLVQLVRLFLIDEVHIVKDENRGPTLEVVVSRMKTVQSVSQTLKNTST 447
Query: 1484 --PIRIVALSSSLSNAKDVAHWL--GCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRL 1539
P+R VA+S+++ NA+D+A WL G + RPV L+ + GF S QT
Sbjct: 448 AIPMRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSNQTEF 507
Query: 1540 ---LSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKD 1596
L++ + I +S +KP +VF +RK + A + ++ +F+ E+
Sbjct: 508 KFDLTLNYKIASVIQMYSDQKPTLVFCATRKGVQQAASVL-------VKDAKFIMTVEQK 560
Query: 1597 --LIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGM 1654
L Y + DS L++ L +G Y H G+ +R++VE F+ G + V+ + +L G+
Sbjct: 561 QRLQKYAYSVRDSKLRDILKDGAAYHHAGMELSDRKVVEGAFTVGDLPVLFTTSTLAMGV 620
Query: 1655 NVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFF 1714
N+ AHLV+I T +Y G + + +Y D+LQM+G A RP D VIM + S +D +
Sbjct: 621 NLPAHLVVIKSTMHYAGGL--FEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTRDKY 678
Query: 1715 KKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNL- 1773
+ L VES L + +H NAEIV TI + AV+++ T LY R +NP++Y
Sbjct: 679 IQMLACRDTVESSLHRHLIEHLNAEIVLHTITDVNIAVEWIRSTLLYIRALKNPSHYGFA 738
Query: 1774 QGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFS 1833
G++ + L EL + L+DL I +++ ++ P G + A+YYI + T++ F
Sbjct: 739 SGLNKDGIEAKLQELCLKNLNDLSSLDLIKMDEGVNFKPTEAGRLMAWYYITFETVKKF- 797
Query: 1834 MSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLN-----NPKFNDPH 1888
+++ K + L+ +I+ E+ +I +R +E L L K P+++ +
Sbjct: 798 YTISGKETLSDLVTLIAGCKEFLDIQLRINEKKTLNTL-NKDPNRITIRFPMEGRIKTRE 856
Query: 1889 VKTNLLLQAHLSRMQL-SAELQSDTEEILSKAIRLIQACVD-VLSSNGWLSPALAAMELA 1946
+K N L+QA L + + L DT +I R+ + D V + + L ++ LA
Sbjct: 857 MKVNCLIQAQLGCIPIQDFALTQDTAKIFRHGSRITRWLSDFVAAQEKKFAVLLNSLILA 916
Query: 1947 QMVTQAMWSKDSYL-KQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIA 2005
+ +W ++ KQL + G+ S I E + E +L
Sbjct: 917 KCFRCKLWENSLHVSKQLEKIGITLSNAIVNAGLTSFKKIEETDARELELILNRHPPFGT 976
Query: 2006 DVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWW 2065
+ P EL E + + S + +V ++ E+ T + + +
Sbjct: 977 QIKETVMYLPKYELKVEQITRYSDTTAEILVTVILRNFEQLQT--------KRTASDSHY 1028
Query: 2066 V--VIGDAKSNSLISIKRLT----LQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQE 2119
V +IGDA N ++ + ++T L+ + K V A + + ++ +S ++G D +
Sbjct: 1029 VTLIIGDA-DNQVVYLHKITDSVLLKAGSWAKKIAVKRALKSEDLSINLISSEFVGLDIQ 1087
Query: 2120 YKFSV 2124
K +V
Sbjct: 1088 QKLTV 1092
>gi|139394648 DNA polymerase theta [Homo sapiens]
Length = 2590
Score = 136 bits (343), Expect = 2e-31
Identities = 135/435 (31%), Positives = 207/435 (47%), Gaps = 66/435 (15%)
Query: 497 ENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFG 556
+NL+ APT AGKT VA + +L+ + + K ++I P S+ +E
Sbjct: 109 KNLVYSAPTSAGKTLVAELLILKRVLEMRK----------KALFILPFVSVAKEKKYYLQ 158
Query: 557 KRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDE 616
GI V G + S+ I VCT E+ + + + E L+ ++++DE
Sbjct: 159 SLFQEVGIKVDGYMGSTSPSRH-FSSLDIAVCTIERANGLINRLIEENKMDLLGMVVVDE 217
Query: 617 IHLLHDD-RGPVLEALVARAI---RNIEMTQED--------VRLIGLSATLPNYEDVATF 664
+H+L D RG +LE L+ + R Q D V+++G+SATLPN E VA++
Sbjct: 218 LHMLGDSHRGYLLELLLTKICYITRKSASCQADLASSLSNAVQIVGMSATLPNLELVASW 277
Query: 665 LRVDPAKGLFYFDNSFRPVPL-EQTYVGIT----EKKAIKRFQIMNEI----------VY 709
L + L++ D FRPVPL E VG + K ++ F+ M ++ Y
Sbjct: 278 LNAE----LYHTD--FRPVPLLESVKVGNSIYDSSMKLVREFEPMLQVKGDEDHVVSLCY 331
Query: 710 EKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQC 769
E I ++ + VL+F S+K K A I L + S V+ + E
Sbjct: 332 ETICDN---HSVLLFCPSKKWCEKLADIIAREFYNLHHQAEGLVKPSECPPVILEQKELL 388
Query: 770 KNLE------------LKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAW 817
+ ++ L+ +P+G A HHAG+T +R ++E F I+VL +T+TL+
Sbjct: 389 EVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLSS 448
Query: 818 GVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQ 877
GVNLPA VII+ T ++ GR L L QM+GRAGR DT GE ILI + E
Sbjct: 449 GVNLPARRVIIR-TPIFG---GR--PLDILTYKQMVGRAGRKGVDTVGESILICKNSEKS 502
Query: 878 YYLSLLNQQL-PIES 891
++LL L P+ S
Sbjct: 503 KGIALLQGSLKPVRS 517
Score = 120 bits (300), Expect = 2e-26
Identities = 131/497 (26%), Positives = 226/497 (45%), Gaps = 77/497 (15%)
Query: 1345 NVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKK 1404
N+ APT +GKT+ AE IL+ +L+ + + ++I P ++A++ FQ+ + K
Sbjct: 110 NLVYSAPTSAGKTLVAELLILKRVLEMRK-KALFILPFVSVAKEKKYYLQSLFQE-VGIK 167
Query: 1405 VVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGEN- 1463
V G TS + +I + T E+ + L R + + + + VVDE+H++G +
Sbjct: 168 VDGYMGSTSPS-RHFSSLDIAVCTIERANGLINRLIEENKMDLLGMVVVDELHMLGDSHR 226
Query: 1464 GPVLEVICSRMRYIS-----------SQIERPIRIVALSSSLSNAKDVAHWLGCSATSTF 1512
G +LE++ +++ YI+ S + ++IV +S++L N + VA WL
Sbjct: 227 GYLLELLLTKICYITRKSASCQADLASSLSNAVQIVGMSATLPNLELVASWLNAEL---- 282
Query: 1513 NFHPNVRPVPLELHIQ-GFNISHTQTRLLSMAKPVY-------HAIT--------KHSPK 1556
+H + RPVPL ++ G +I + +L+ +P+ H ++ HS
Sbjct: 283 -YHTDFRPVPLLESVKVGNSIYDSSMKLVREFEPMLQVKGDEDHVVSLCYETICDNHS-- 339
Query: 1557 KPVIVFVPSRKQTRLTAIDILTTCAADIQRQ-----RFLHCT-----EKDLIPYLEKLS- 1605
V++F PS+K A DI+ ++ Q + C +K+L+ +++L
Sbjct: 340 --VLLFCPSKKWCEKLA-DIIAREFYNLHHQAEGLVKPSECPPVILEQKELLEVMDQLRR 396
Query: 1606 -----DSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHL 1660
DS L++T+ GV + H GL+ ER ++E F G I+V+ A+ +L G+N+ A
Sbjct: 397 LPSGLDSVLQKTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARR 456
Query: 1661 VIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYE 1720
VII T + G+ + Y QMVG A R D G +++C+ S+K L
Sbjct: 457 VIIR-TPIFGGRPLDILTYK-----QMVGRAGRKGVDTVGESILICKNSEKSKGIALLQG 510
Query: 1721 PL-PVESHLDHCMHDHFNAEIVTKTIE--------NKQDAVDYLTWTFLYRRMTQNPNYY 1771
L PV S L + ++ +E QD Y TFL M +
Sbjct: 511 SLKPVRSCLQRREGEEVTGSMIRAILEIIVGGVASTSQDMHTYAACTFLAASMKEGK--- 567
Query: 1772 NLQGISHRHLSDHLSEL 1788
QGI S L +
Sbjct: 568 --QGIQRNQESVQLGAI 582
>gi|110556640 DNA helicase HEL308 [Homo sapiens]
Length = 1101
Score = 130 bits (328), Expect = 1e-29
Identities = 150/606 (24%), Positives = 264/606 (43%), Gaps = 90/606 (14%)
Query: 425 NKRCQLPDGSFRRQRKGY---EEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTL 481
N + Q P S +Q K EE++V K S L P LP + + FK +
Sbjct: 276 NAKAQTPIFSRSKQLKDTLLSEEINVA--KKTVESSSNDLGPFYSLPSKVRDLYAQFKGI 333
Query: 482 NRI----QSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFK 537
++ + L +++ +NL+ PT GKT VA + ML+E+ D
Sbjct: 334 EKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQEL-LCCRKD--------- 383
Query: 538 IIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQ------IIVCTPE 591
++ I P ++VQE + L+++GI + ++ K T+ + + T E
Sbjct: 384 VLMILPYVAIVQEKISG----LSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIE 439
Query: 592 KWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLIG 650
K + E + L+++DE+H++ + RG LE +A+ + + TQ +IG
Sbjct: 440 KGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQ----IIG 495
Query: 651 LSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYE 710
+SATL N ED+ FL+ + Y+ + FRPV L++ Y+ I + + N + +
Sbjct: 496 MSATLNNVEDLQKFLQAE------YYTSQFRPVELKE-YLKINDTIYEVDSKAENGMTFS 548
Query: 711 KIMEHAGKNQV---------------------LVFVHSRKETGKTARAIRDMCLEKDTLG 749
+++ + + + LVF S+K A I L K+ L
Sbjct: 549 RLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF-LSKEYLK 607
Query: 750 LFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVL 809
+E + L+ LK +P+G A HH+G+T +R L+E+ ++ + +
Sbjct: 608 HKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLF 667
Query: 810 VSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGIL 869
T+TLA GVNLPA VI++ V L QM+GRAGR DT GE IL
Sbjct: 668 TCTSTLAAGVNLPARRVILRAPYVAK------EFLKRNQYKQMIGRAGRAGIDTIGESIL 721
Query: 870 ITSHGELQYYLSLLNQQLP-----IESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAY 924
I + Q L L+ + L + + + + + I L N D +++ +
Sbjct: 722 ILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTF 781
Query: 925 LYIR---MLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTG-NFQ 980
++ +L+ +L+ I+ + L+ T +L K+ + K +++ NF
Sbjct: 782 FGVQQKVLLKEKSLWEITVESLR------------YLTEKGLLQKDTIYKSEEEVQYNFH 829
Query: 981 VTELGR 986
+T+LGR
Sbjct: 830 ITKLGR 835
Score = 90.9 bits (224), Expect = 1e-17
Identities = 110/453 (24%), Positives = 189/453 (41%), Gaps = 63/453 (13%)
Query: 1345 NVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKK 1404
N+ PT GKT+ AE +L+ LL + + I P A+ ++ + F L
Sbjct: 354 NLIYSLPTSGGKTLVAEILMLQELLCCRKD-VLMILPYVAIVQEK-ISGLSSFGIELGFF 411
Query: 1405 VVLLTGETST--DLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIG-G 1461
V G K K ++ I+T EK L + + ++ L VVDE+H+IG G
Sbjct: 412 VEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEG 471
Query: 1462 ENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSA-TSTFNFHPNVRP 1520
G LE+ +++ Y S + +I+ +S++L+N +D+ +L TS F RP
Sbjct: 472 SRGATLEMTLAKILYTS----KTTQIIGMSATLNNVEDLQKFLQAEYYTSQF------RP 521
Query: 1521 VPLELHIQG--------------------FNISHTQTRLLSMAKPVYHAITKHSPKKPVI 1560
V L+ +++ N ++ T + +T+ P +
Sbjct: 522 VELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCL 581
Query: 1561 VFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSD-------STLKETL 1613
VF PS+K A I + + +L EK+ ++ L + LK T+
Sbjct: 582 VFCPSKKNCENVAEMICKFLSKE-----YLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTI 636
Query: 1614 LNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKI 1673
GV Y H GL+ ER+L+E+ +S+G + + + +L G+N+ A VI+ Y +
Sbjct: 637 PFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILR-APYVAKEF 695
Query: 1674 HAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMH 1733
Y QM+G A R D G +++ Q K + + +PL E+ H +
Sbjct: 696 LKRNQYK-----QMIGRAGRAGIDTIGESILILQEKDKQQVLELITKPL--ENCYSHLVQ 748
Query: 1734 DH-------FNAEIVTKTIENKQDAVDYLTWTF 1759
+ F + I K N D ++ TF
Sbjct: 749 EFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTF 781
>gi|67782311 superkiller viralicidic activity 2-like homolog [Homo
sapiens]
Length = 1246
Score = 112 bits (280), Expect = 4e-24
Identities = 128/494 (25%), Positives = 214/494 (43%), Gaps = 82/494 (16%)
Query: 1292 PEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPF-FNPIQTQVFNTVY-NSDDNVFVG 1349
PE PP++ P+ ++ + + Q F + F P Q ++ D+VFV
Sbjct: 272 PEAPEPPSQEQWAIPVDATSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVA 331
Query: 1350 APTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLT 1409
A T +GKT+ AE+AI L Q R +Y +P++AL+ Q + D+ F D V LLT
Sbjct: 332 AHTSAGKTVVAEYAI--ALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGD-----VGLLT 384
Query: 1410 GETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGG-ENGPVLE 1468
G D++L + + +I T E + S + ++++ + DEVH I E G V E
Sbjct: 385 G----DVQLHPEASCLIMTTE--ILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 1469 VICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLG-CSATSTFNFHPNVRPVPLELHI 1527
+ + + I+ LS+++ NA + A W+G + RPVPLE ++
Sbjct: 439 EVL-------IMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 1528 QGFNISHTQTRLLSM--------AKPVYHAI-------TKHS------------------ 1554
N S TQ L + K Y A+ +KH+
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 1555 -------------PKKPVIVFVPSR-----KQTRLTAIDILTTCAADIQRQRFLHCTEKD 1596
+ PV+VF SR + + LT++D LTT + + FL
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLD-LTTSSEKSEIHLFLQRCLAR 610
Query: 1597 LIPYLEKLSDSTLKETLLN-GVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMN 1655
L +L LLN G+G H G+ P+ + +VE LFS G ++V+ A+ + G+N
Sbjct: 611 LRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVN 670
Query: 1656 VAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQG---SKKD 1712
+ A V+ + ++G + D + +QM G A R D G +++C+G D
Sbjct: 671 MPARTVVFDSMRKHDGS--TFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMAD 728
Query: 1713 FFKKFLYEPLPVES 1726
+ + +P ++S
Sbjct: 729 LHRMMMGKPSQLQS 742
Score = 99.4 bits (246), Expect = 3e-20
Identities = 129/511 (25%), Positives = 213/511 (41%), Gaps = 100/511 (19%)
Query: 411 LEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKY 470
LEDLV + S ++ P E+ +P P G +L+P
Sbjct: 257 LEDLVLKEASTAVSTPEAPEPPSQ--------EQWAIPVDATSPVGDFYRLIPQPAF--- 305
Query: 471 AQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGT 530
Q FE + + Q+ L+ LE +++ + A T AGKT VA + KH+
Sbjct: 306 -QWAFE--PDVFQKQAILH---LERHDSVFVAAHTSAGKTVVAEYAIALA-QKHMT---- 354
Query: 531 INVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTP 590
+ IY +P+++L + F G+ LTGD QL E ++ T
Sbjct: 355 ------RTIYTSPIKALSNQKFRDFRNTFGDVGL----LTGDVQLHPE----ASCLIMTT 400
Query: 591 EKWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLI 649
E + G + + + +I DE+H ++D +RG V E ++ M + V +I
Sbjct: 401 EILRSMLYSGSD--VIRDLEWVIFDEVHYINDVERGVVWEEVLI-------MLPDHVSII 451
Query: 650 GLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ-TYVGITEKKAIKRFQIMN--- 705
LSAT+PN + A ++ + ++ RPVPLE + G + K + F +++
Sbjct: 452 LLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRG 511
Query: 706 -----------EIVYEKIMEHA---GKNQ----------------------------VLV 723
E E++ +HA G Q V+V
Sbjct: 512 AFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVV 571
Query: 724 FVHSRKETGKTARAIRDMCL----EKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLP 779
F SR + A + + L EK + LFL+ A + Q L + +LL
Sbjct: 572 FTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQV--LHMSELLN 629
Query: 780 YGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKG 839
G +HH+G+ + + +VE LF+ ++VL +T T A GVN+PA TV+ + + +
Sbjct: 630 RGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKH--DGS 687
Query: 840 RWTELGALDILQMLGRAGRPQYDTKGEGILI 870
+ +L + +QM GRAGR D G IL+
Sbjct: 688 TFRDLLPGEYVQMAGRAGRRGLDPTGTVILL 718
>gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sapiens]
Length = 1042
Score = 96.3 bits (238), Expect = 3e-19
Identities = 112/461 (24%), Positives = 193/461 (41%), Gaps = 78/461 (16%)
Query: 1324 KFPFF-NPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPM 1382
++PF + Q + V N+ +V V A T +GKT+CAE+AI L + R ++ +P+
Sbjct: 135 EYPFILDAFQREAIQCVDNNQ-SVLVSAHTSAGKTVCAEYAIALALREKQ--RVIFTSPI 191
Query: 1383 EALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQR 1442
+AL+ Q Y + YE+FQD V L+TG D+ + + ++ T E + S ++
Sbjct: 192 KALSNQKYREMYEEFQD-----VGLMTG----DVTINPTASCLVMTTE--ILRSMLYRGS 240
Query: 1443 KNVQNINLFVVDEVHLI-GGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVA 1501
+ ++ + + DE+H + E G V E + + V LS+++ NA+ A
Sbjct: 241 EVMREVAWVIFDEIHYMRDSERGVVWEETI-------ILLPDNVHYVFLSATIPNARQFA 293
Query: 1502 HWL-GCSATSTFNFHPNVRPVPLELHI-----QGFNI------------SHTQTRLLSMA 1543
W+ + + RP PL+ +I G ++ +T ++L A
Sbjct: 294 EWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDA 353
Query: 1544 KPVYHAITK------HSPK--------------KPVIVFVPSRKQTRLTAIDILTTCAAD 1583
+ K P +PVI+F S+K A+ + D
Sbjct: 354 GDLAKGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQM---TKLD 410
Query: 1584 IQRQRFLHCTEKDLIPYLEKLSDSTLK--------ETLLNGVGYLHEGLSPMERRLVEQL 1635
E+ ++ LSD K L G+G H GL P+ + +E L
Sbjct: 411 FNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEIL 470
Query: 1636 FSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPL 1695
FS G I+ + A+ + G+N+ A V+ + + ++GK ++ Y +QM G A R
Sbjct: 471 FSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEY--IQMSGRAGRRG 528
Query: 1696 QDDEGRCVIMCQGSKKDFFKKFLY----EPLPVESHLDHCM 1732
DD G ++M K L +PL HL + M
Sbjct: 529 MDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNM 569
Score = 87.0 bits (214), Expect = 2e-16
Identities = 105/458 (22%), Positives = 191/458 (41%), Gaps = 81/458 (17%)
Query: 457 SEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKT---NVA 513
+EE LP++ P+ +A E L+ Q + + ++ ++++L+ A T AGKT A
Sbjct: 118 AEEDYLPLK--PRVGKAAKEYPFILDAFQREAIQC-VDNNQSVLVSAHTSAGKTVCAEYA 174
Query: 514 LMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDH 573
+ LRE ++I+ +P+++L + + G+ ++T +
Sbjct: 175 IALALRE--------------KQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTIN- 219
Query: 574 QLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALV 632
+V T E + +G E + V +I DEIH + D +RG V E
Sbjct: 220 -------PTASCLVMTTEILRSMLYRGSE--VMREVAWVIFDEIHYMRDSERGVVWE--- 267
Query: 633 ARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ----- 687
I + ++V + LSAT+PN A ++ + +RP PL+
Sbjct: 268 ----ETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPA 323
Query: 688 ----TYVGITEKKAIKR------FQIMNEI-----------------------VYEKIME 714
++ + E + Q++ + + + IME
Sbjct: 324 GGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIME 383
Query: 715 HAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREG-SASTEVLRTEAEQCKNLE 773
V++F S+K+ A + + D + E S + + L E ++ +E
Sbjct: 384 R-NFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVE 442
Query: 774 -LKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQ 832
+ LL G IHH G+ + + +E LF++ I+ L +T T A G+N+PA TV+ +
Sbjct: 443 HVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNAR 502
Query: 833 VYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILI 870
+ + RW G + +QM GRAGR D +G IL+
Sbjct: 503 KFDGKDFRWISSG--EYIQMSGRAGRRGMDDRGIVILM 538
>gi|6005872 SEC63-like protein [Homo sapiens]
Length = 760
Score = 74.3 bits (181), Expect = 1e-12
Identities = 63/253 (24%), Positives = 128/253 (50%), Gaps = 32/253 (12%)
Query: 1824 INYTTIELFSMSLNAKTKVRGLIEIISNAAEYE-----NIPIRHHEDNLLRQLAQKVPH- 1877
I T I + + ++ LI +++ A+E++ + R ++ L+ QL +++
Sbjct: 225 IRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSI 284
Query: 1878 --KLNNPKFNDPH-VKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVL---- 1930
K N P P+ +K +LL +HL+RM++ L+ D + +L K L+Q V+V+
Sbjct: 285 NLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLI 344
Query: 1931 ------SSNGWLSPALAAME----LAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDK--- 1977
+ +P LA++E L+QM Q + S L QLPH ++++R ++
Sbjct: 345 VMARNREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKY 404
Query: 1978 GVESVFDIMEMEDEERNALLQ-LTDSQIADVARFCNRYP--NIELSYEVV---DKDSIRS 2031
++++ D++ +++ +R+ LL L D + +V +P +++ +V+ D ++I
Sbjct: 405 KIKTIQDLVSLKESDRHTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITV 464
Query: 2032 GGPVVVLVQLERE 2044
G V VLV+L R+
Sbjct: 465 GSLVTVLVKLTRQ 477
Score = 69.3 bits (168), Expect = 4e-11
Identities = 36/93 (38%), Positives = 57/93 (61%), Gaps = 3/93 (3%)
Query: 2041 LEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKR--LTLQQKAKVKLDFVAPA 2098
LE + ++T PV + FP++++E WW+ I D K +LIS+ TL+ +V+L F AP
Sbjct: 628 LETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPG 687
Query: 2099 -TGAHNYTLYFMSDAYMGCDQEYKFSVDVKEAE 2130
G + YT++ SD+YMG DQ ++V EA+
Sbjct: 688 KPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAK 720
>gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sapiens]
Length = 1712
Score = 65.5 bits (158), Expect = 5e-10
Identities = 46/166 (27%), Positives = 80/166 (48%), Gaps = 8/166 (4%)
Query: 1339 VYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQ 1398
V + +++ + APT SGKT + + + ++L +S +G VY+ P +AL QV +F
Sbjct: 774 VVDKNESAVIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFT 833
Query: 1399 DRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHL 1458
L VL T ++I+ P ++IL ++ V+ I + DEVH
Sbjct: 834 KNLPSGEVLCGVFTREYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHC 893
Query: 1459 IGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWL 1504
+GGE G + ++ I P +ALS+++SN + + WL
Sbjct: 894 LGGEIGAEI------WEHLLVMIRCP--FLALSATISNPEHLTEWL 931
Score = 65.5 bits (158), Expect = 5e-10
Identities = 63/241 (26%), Positives = 106/241 (43%), Gaps = 25/241 (10%)
Query: 631 LVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYV 690
L+ +R +E L L A E V+TFL+ + P ++ +V
Sbjct: 1116 LLVEKLRKMEKLPALFFLFKLGAVENAAESVSTFLKKKQ-------ETKRPPKADKEAHV 1168
Query: 691 GITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGL 750
+ + +K+ +I+ EK + +N +H + +++ + +D
Sbjct: 1169 MANKLRKVKKSIEKQKIIDEKSQKKT-RNVDQSLIHEAEHDNLVKCLEKNLEIPQDCT-- 1225
Query: 751 FLREGSASTEVL-----RTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKH 805
+ + + TE L R + E+ K ELK L G HH+ M+ ++ LVE LF +
Sbjct: 1226 YADQKAVDTETLQKVFGRVKFER-KGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGY 1284
Query: 806 IQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKG 865
++V+ +T TLA GVN+P +V+ VY L AL+ QM GRAGR D G
Sbjct: 1285 LRVVTATGTLALGVNMPCKSVVFAQNSVY---------LDALNYRQMSGRAGRRGQDLMG 1335
Query: 866 E 866
+
Sbjct: 1336 D 1336
Score = 54.3 bits (129), Expect = 1e-06
Identities = 39/178 (21%), Positives = 84/178 (47%), Gaps = 24/178 (13%)
Query: 493 LETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMV 552
++ +E+ ++ APT +GKT + CM + + + DD ++Y+AP ++LV ++
Sbjct: 775 VDKNESAVIVAPTSSGKTYASYYCMEKVLKES---------DDGVVVYVAPTKALVNQVA 825
Query: 553 GS----FGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQL 608
+ F K L + + T ++ + + Q+++ P ++I+ + + +
Sbjct: 826 ATVQNRFTKNLPSGEVLCGVFTREY---RHDALNCQVLITVPACFEILLLAPHRQNWVKK 882
Query: 609 VRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLR 666
+R +I DE+H L + G + + IR + LSAT+ N E + +L+
Sbjct: 883 IRYVIFDEVHCLGGEIGAEIWEHLLVMIR--------CPFLALSATISNPEHLTEWLQ 932
Score = 45.4 bits (106), Expect = 6e-04
Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 36/169 (21%)
Query: 1552 KHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDL-IP----YLEKLSD 1606
K S +K I+ S+K+TR ++ + + + + C EK+L IP Y ++ +
Sbjct: 1177 KKSIEKQKIIDEKSQKKTR----NVDQSLIHEAEHDNLVKCLEKNLEIPQDCTYADQKAV 1232
Query: 1607 ST------------------LKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASR 1648
T LK G+GY H +S E++LVE LF G ++VV A+
Sbjct: 1233 DTETLQKVFGRVKFERKGEELKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATG 1292
Query: 1649 SLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQD 1697
+L G+N+ V+ Y + + QM G A R QD
Sbjct: 1293 TLALGVNMPCKSVVFAQNSVYLDAL---------NYRQMSGRAGRRGQD 1332
>gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Homo
sapiens]
Length = 1706
Score = 57.8 bits (138), Expect = 1e-07
Identities = 48/168 (28%), Positives = 78/168 (46%), Gaps = 8/168 (4%)
Query: 1322 QDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITP 1381
QD P N Q ++ + V ++ V V APT SGKT + + + ++L +S G VY+ P
Sbjct: 740 QDFIP--NAWQQELLDVVDKNESAVIV-APTSSGKTYASYYCMEKVLRESDVGVVVYVAP 796
Query: 1382 MEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQ 1441
++L QV +F L L T + ++I+ PE ++IL +
Sbjct: 797 AKSLVGQVAATVENRFTKTLPAGRTLCGAFTRDYCHNVLNCQVLITVPECFEILLLAPHR 856
Query: 1442 RKNVQNINLFVVDEVHLIGGENGP-----VLEVICSRMRYISSQIERP 1484
+K V+ I + DEVH +G E G +L +I +S+ I P
Sbjct: 857 QKWVERIRYVIFDEVHYLGREVGAKFWELLLVIIRCPFLVLSATINNP 904
Score = 55.1 bits (131), Expect = 7e-07
Identities = 35/93 (37%), Positives = 47/93 (50%), Gaps = 9/93 (9%)
Query: 773 ELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQ 832
ELK L G HH+ M ++ VE LF I+V+ +T TLA G+++P +V+
Sbjct: 1236 ELKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVFAQDS 1295
Query: 833 VYSPEKGRWTELGALDILQMLGRAGRPQYDTKG 865
VY L AL+ QM GRAGR D G
Sbjct: 1296 VY---------LDALNYRQMSGRAGRRGQDLLG 1319
Score = 50.8 bits (120), Expect = 1e-05
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 16/149 (10%)
Query: 493 LETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMV 552
++ +E+ ++ APT +GKT + CM + + + + V ++Y+AP +SLV ++
Sbjct: 755 VDKNESAVIVAPTSSGKTYASYYCM-----EKVLRESDVGV----VVYVAPAKSLVGQVA 805
Query: 553 GS----FGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQL 608
+ F K L T D+ C ++ Q+++ PE ++I+ + + +
Sbjct: 806 ATVENRFTKTLPAGRTLCGAFTRDY--CHNVLNC-QVLITVPECFEILLLAPHRQKWVER 862
Query: 609 VRLIILDEIHLLHDDRGPVLEALVARAIR 637
+R +I DE+H L + G L+ IR
Sbjct: 863 IRYVIFDEVHYLGREVGAKFWELLLVIIR 891
Score = 40.0 bits (92), Expect = 0.024
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 1609 LKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQY 1668
LK G+GY H + E+ VE LF G I+VV A+ +L G+++ V+
Sbjct: 1237 LKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVFAQDSV 1296
Query: 1669 YNGKIHAYVDYPIYDVLQMVGHANRPLQD 1697
Y + + QM G A R QD
Sbjct: 1297 YLDAL---------NYRQMSGRAGRRGQD 1316
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 47.0 bits (110), Expect = 2e-04
Identities = 73/312 (23%), Positives = 131/312 (41%), Gaps = 37/312 (11%)
Query: 366 TEKEDLIREERSRRERVRQSR----MDTDLETMDLDQG--GEALAPRQVLDLEDLVFTQG 419
T K+ ++ ++ + E + + ++ E +DL G R++L+ D +
Sbjct: 269 TTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEY 328
Query: 420 SHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFK 479
F N ++P+ + Q EEV+V L+ + + + P + + + Q G K
Sbjct: 329 EPFRKNFYVEVPELAKMSQ----EEVNVFRLEMEGITVKGKGCP-KPIKSWVQCGIS-MK 382
Query: 480 TLNRIQSKLYRA----------ALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDG 529
LN ++ Y A+ + +L+ A TG+GKT L+ M R HI
Sbjct: 383 ILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFR----HIMDQR 438
Query: 530 TINVDDFKI-IYIAPMRSLVQEMVGSFGKRLATYGITVAEL---TGDHQLCKEEISATQI 585
++ + I + + P R L ++ K T G+ V + TG + E +I
Sbjct: 439 SLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEI 498
Query: 586 IVCTPEKW-DIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQE 644
IVCTP + D++ G T + V ++LDE + D E V R + N+ +
Sbjct: 499 IVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFD---MGFEPQVMRIVDNV---RP 552
Query: 645 DVRLIGLSATLP 656
D + + SAT P
Sbjct: 553 DRQTVMFSATFP 564
>gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]
Length = 991
Score = 45.4 bits (106), Expect = 6e-04
Identities = 89/413 (21%), Positives = 156/413 (37%), Gaps = 104/413 (25%)
Query: 474 GFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINV 533
GF+ FKT +Q A ++ ++++ +C PTGAGK+ + L + K I
Sbjct: 25 GFDSFKT--PLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL--LAKGIT------- 73
Query: 534 DDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTG--DHQLCKE-------EISATQ 584
I ++P+ +L+Q+ V L T + V+ L Q KE E T+
Sbjct: 74 -----IVVSPLIALIQDQVD----HLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTK 124
Query: 585 IIVCTPEKWDIITRKGGERTYTQLVR-----LIILDEIHLL----HDDRGPVLEALVARA 635
I+ TPE + + T LV +++DE H + HD R L R+
Sbjct: 125 ILYITPE---MAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRS 181
Query: 636 IRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEK 695
+ + +AT EDV L + +F K
Sbjct: 182 ----RLGHAPCVALTATATPQVQEDVFAALHLKKPVAIF--------------------K 217
Query: 696 KAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREG 755
R + ++ +++++ N ++D CL+ LG +G
Sbjct: 218 TPCFRANLFYDVQFKELISDPYGN------------------LKDFCLK--ALGQEADKG 257
Query: 756 SASTEVLRTEA-EQCKNLELK-DLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTA 813
+ ++ E C+ L ++ +HAG+ +RTLV++ + ++ + V+V+T
Sbjct: 258 LSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATI 317
Query: 814 TLAWGVN-----LPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQY 861
+ GV+ AH I K Y E GR GR G+P +
Sbjct: 318 SFGMGVDKANVRFVAHWNIAKSMAGYYQESGR------------AGRDGKPSW 358
Score = 34.3 bits (77), Expect = 1.3
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Query: 1327 FFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALA 1386
F P+Q V + +VFV PTG+GK++C + L ++G + ++P+ AL
Sbjct: 29 FKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL-----LAKGITIVVSPLIALI 83
Query: 1387 E 1387
+
Sbjct: 84 Q 84
>gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens]
Length = 410
Score = 45.4 bits (106), Expect = 6e-04
Identities = 89/413 (21%), Positives = 156/413 (37%), Gaps = 104/413 (25%)
Query: 474 GFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINV 533
GF+ FKT +Q A ++ ++++ +C PTGAGK+ + L + K I
Sbjct: 25 GFDSFKT--PLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL--LAKGIT------- 73
Query: 534 DDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTG--DHQLCKE-------EISATQ 584
I ++P+ +L+Q+ V L T + V+ L Q KE E T+
Sbjct: 74 -----IVVSPLIALIQDQVD----HLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTK 124
Query: 585 IIVCTPEKWDIITRKGGERTYTQLVR-----LIILDEIHLL----HDDRGPVLEALVARA 635
I+ TPE + + T LV +++DE H + HD R L R+
Sbjct: 125 ILYITPE---MAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRS 181
Query: 636 IRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEK 695
+ + +AT EDV L + +F K
Sbjct: 182 ----RLGHAPCVALTATATPQVQEDVFAALHLKKPVAIF--------------------K 217
Query: 696 KAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREG 755
R + ++ +++++ N ++D CL+ LG +G
Sbjct: 218 TPCFRANLFYDVQFKELISDPYGN------------------LKDFCLK--ALGQEADKG 257
Query: 756 SASTEVLRTEA-EQCKNLELK-DLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTA 813
+ ++ E C+ L ++ +HAG+ +RTLV++ + ++ + V+V+T
Sbjct: 258 LSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATI 317
Query: 814 TLAWGVN-----LPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQY 861
+ GV+ AH I K Y E GR GR G+P +
Sbjct: 318 SFGMGVDKANVRFVAHWNIAKSMAGYYQESGR------------AGRDGKPSW 358
Score = 34.3 bits (77), Expect = 1.3
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Query: 1327 FFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALA 1386
F P+Q V + +VFV PTG+GK++C + L ++G + ++P+ AL
Sbjct: 29 FKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL-----LAKGITIVVSPLIALI 83
Query: 1387 E 1387
+
Sbjct: 84 Q 84
>gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens]
Length = 435
Score = 45.4 bits (106), Expect = 6e-04
Identities = 89/413 (21%), Positives = 156/413 (37%), Gaps = 104/413 (25%)
Query: 474 GFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINV 533
GF+ FKT +Q A ++ ++++ +C PTGAGK+ + L + K I
Sbjct: 25 GFDSFKT--PLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL--LAKGIT------- 73
Query: 534 DDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTG--DHQLCKE-------EISATQ 584
I ++P+ +L+Q+ V L T + V+ L Q KE E T+
Sbjct: 74 -----IVVSPLIALIQDQVD----HLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTK 124
Query: 585 IIVCTPEKWDIITRKGGERTYTQLVR-----LIILDEIHLL----HDDRGPVLEALVARA 635
I+ TPE + + T LV +++DE H + HD R L R+
Sbjct: 125 ILYITPE---MAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRS 181
Query: 636 IRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEK 695
+ + +AT EDV L + +F K
Sbjct: 182 ----RLGHAPCVALTATATPQVQEDVFAALHLKKPVAIF--------------------K 217
Query: 696 KAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREG 755
R + ++ +++++ N ++D CL+ LG +G
Sbjct: 218 TPCFRANLFYDVQFKELISDPYGN------------------LKDFCLK--ALGQEADKG 257
Query: 756 SASTEVLRTEA-EQCKNLELK-DLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTA 813
+ ++ E C+ L ++ +HAG+ +RTLV++ + ++ + V+V+T
Sbjct: 258 LSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATI 317
Query: 814 TLAWGVN-----LPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQY 861
+ GV+ AH I K Y E GR GR G+P +
Sbjct: 318 SFGMGVDKANVRFVAHWNIAKSMAGYYQESGR------------AGRDGKPSW 358
Score = 34.3 bits (77), Expect = 1.3
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Query: 1327 FFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALA 1386
F P+Q V + +VFV PTG+GK++C + L ++G + ++P+ AL
Sbjct: 29 FKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL-----LAKGITIVVSPLIALI 83
Query: 1387 E 1387
+
Sbjct: 84 Q 84
>gi|27886568 interferon induced with helicase C domain 1 [Homo
sapiens]
Length = 1025
Score = 43.5 bits (101), Expect = 0.002
Identities = 48/194 (24%), Positives = 88/194 (45%), Gaps = 15/194 (7%)
Query: 471 AQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGT 530
A+A E L Q ++ + ALE +N+++C PTG+GKT VA+ + K
Sbjct: 298 ARASPEPELQLRPYQMEVAQPALE-GKNIIICLPTGSGKTRVAVYIAKDHLDKKKKAS-- 354
Query: 531 INVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQL---CKEEISATQIIV 587
+ K+I + LV+++ + V L+GD QL E + + II+
Sbjct: 355 ---EPGKVIVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIII 411
Query: 588 CTPE--KWDIITRKGGERTYTQL--VRLIILDEIHLLHDDR--GPVLEALVARAIRNIEM 641
T + + ++ + GE QL LII+DE H + + ++ + + ++N +
Sbjct: 412 STAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRL 471
Query: 642 TQEDVRLIGLSATL 655
+E+ +I L L
Sbjct: 472 KKENKPVIPLPQIL 485
Score = 35.0 bits (79), Expect = 0.79
Identities = 34/126 (26%), Positives = 64/126 (50%), Gaps = 16/126 (12%)
Query: 1345 NVFVGAPTGSGKTICAEFA----ILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDR 1400
N+ + PTGSGKT A + + + S G+ + + L EQ++ ++FQ
Sbjct: 324 NIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLVEQLFR---KEFQPF 380
Query: 1401 LNK--KVVLLTGETSTDL---KLLGKGNIIISTPE--KWDILSRRWKQRKNVQ--NINLF 1451
L K +V+ L+G+T + +++ +IIIST + + +L+ + VQ + +L
Sbjct: 381 LKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLI 440
Query: 1452 VVDEVH 1457
++DE H
Sbjct: 441 IIDECH 446
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapiens]
Length = 491
Score = 43.5 bits (101), Expect = 0.002
Identities = 58/269 (21%), Positives = 115/269 (42%), Gaps = 24/269 (8%)
Query: 1312 LRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQS 1371
+ + +++ F PIQ Q + + + + APTGSGKT+ IL L Q
Sbjct: 64 INSRLLQNILDAGFQMPTPIQMQAIPVMLHGRE-LLASAPTGSGKTLAFSIPILMQLKQP 122
Query: 1372 SEG--RCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLG-----KGNI 1424
+ R + I+P LA Q++ + K + ++ ++ + + K G K +I
Sbjct: 123 ANKGFRALIISPTRELASQIHRELI-KISEGTGFRIHMI-HKAAVAAKKFGPKSSKKFDI 180
Query: 1425 IISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLI--GGENGPVLEVICSRMRYISSQIE 1482
+++TP + L ++ ++ ++ VVDE + G+ G ++ + S ++
Sbjct: 181 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 240
Query: 1483 RPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQT-RLLS 1541
R + S + A DV W + + + R +E Q ++T +LL+
Sbjct: 241 RAM------FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLA 294
Query: 1542 MAKPVYHAITKHSPKKPVIVFVPSRKQTR 1570
M + + K PV+VFV S ++ +
Sbjct: 295 MRE-----LVKKGFNPPVLVFVQSIERAK 318
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapiens]
Length = 599
Score = 43.5 bits (101), Expect = 0.002
Identities = 58/269 (21%), Positives = 115/269 (42%), Gaps = 24/269 (8%)
Query: 1312 LRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQS 1371
+ + +++ F PIQ Q + + + + APTGSGKT+ IL L Q
Sbjct: 172 INSRLLQNILDAGFQMPTPIQMQAIPVMLHGRE-LLASAPTGSGKTLAFSIPILMQLKQP 230
Query: 1372 SEG--RCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLG-----KGNI 1424
+ R + I+P LA Q++ + K + ++ ++ + + K G K +I
Sbjct: 231 ANKGFRALIISPTRELASQIHRELI-KISEGTGFRIHMI-HKAAVAAKKFGPKSSKKFDI 288
Query: 1425 IISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLI--GGENGPVLEVICSRMRYISSQIE 1482
+++TP + L ++ ++ ++ VVDE + G+ G ++ + S ++
Sbjct: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348
Query: 1483 RPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQT-RLLS 1541
R + S + A DV W + + + R +E Q ++T +LL+
Sbjct: 349 RAM------FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLA 402
Query: 1542 MAKPVYHAITKHSPKKPVIVFVPSRKQTR 1570
M + + K PV+VFV S ++ +
Sbjct: 403 MRE-----LVKKGFNPPVLVFVQSIERAK 426
Score = 32.0 bits (71), Expect = 6.7
Identities = 55/272 (20%), Positives = 109/272 (40%), Gaps = 33/272 (12%)
Query: 367 EKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANK 426
+KE+ + E + + + ++ M +++ + + + ++ + +ED + S + K
Sbjct: 73 KKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEA-KIEDKKVQRESKLTSGK 131
Query: 427 RCQLPDGSFRRQRKGYEEVHVPALK-PKPFGSEEQLLPVEKLPKYAQAGF--EGFKTLNR 483
L R ++ +HV P P + +QL K+ GF+
Sbjct: 132 LENLRKEKINFLRNKHK-IHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 190
Query: 484 IQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAP 543
IQ + L E LL APTG+GKT + +L ++ + N F+ + I+P
Sbjct: 191 IQMQAIPVMLHGRE-LLASAPTGSGKTLAFSIPILMQLKQPAN-------KGFRALIISP 242
Query: 544 MRSLVQEMVGSFGKRLATYGITVAELTG--DHQLCKEEISATQ----------IIVCTPE 591
R L ++ I ++E TG H + K ++A + I+V TP
Sbjct: 243 TRELASQIHREL--------IKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPN 294
Query: 592 KWDIITRKGGERTYTQLVRLIILDEIHLLHDD 623
+ + ++ V +++DE L +D
Sbjct: 295 RLIYLLKQDPPGIDLASVEWLVVDESDKLFED 326
>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapiens]
Length = 600
Score = 43.5 bits (101), Expect = 0.002
Identities = 46/166 (27%), Positives = 78/166 (46%), Gaps = 18/166 (10%)
Query: 1305 QPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAI 1364
+ LPV L +L + FP+ P+Q+ + D V A TGSGKT+ I
Sbjct: 10 ESLPVP-LHPQVLGALRELGFPYMTPVQSATIPLFMRNKD-VAAEAVTGSGKTLAFVIPI 67
Query: 1365 LRML------LQSSEGRCVYITPMEALAEQV--YMDWYEKFQDRLNKKVVL---LTGETS 1413
L +L L+ S+ + ITP LA Q+ + + K ++ + + GE
Sbjct: 68 LEILLRREEKLKKSQVGAIIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDV 127
Query: 1414 TDLKLLGKGNIIISTPEKWDILSRRWKQRKN----VQNINLFVVDE 1455
K G GNII++TP + + + RR + + V+++++ V+DE
Sbjct: 128 ERFKQQG-GNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDE 172
>gi|29294649 dicer1 [Homo sapiens]
Length = 1922
Score = 41.6 bits (96), Expect = 0.008
Identities = 47/223 (21%), Positives = 95/223 (42%), Gaps = 28/223 (12%)
Query: 448 PALKPKPFGSEEQLLPVEK-------LPKYAQAGFEGFKTLNRIQSKLYRAALETDENLL 500
PAL+P + + P LP +A + T + Q +L AAL D N +
Sbjct: 4 PALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAAL--DHNTI 61
Query: 501 LCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSF----G 556
+C TG+GKT +A++ + +E+ I G + + + +++ + V + V +
Sbjct: 62 VCLNTGSGKTFIAVL-LTKELSYQIR--GDFSRNGKRTVFLVNSANQVAQQVSAVRTHSD 118
Query: 557 KRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQL--VRLIIL 614
++ Y + + +E + Q+++ T + + G Y L + L++
Sbjct: 119 LKVGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNG----YLSLSDINLLVF 174
Query: 615 DEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPN 657
DE HL +L+ ++ E R++GL+A++ N
Sbjct: 175 DECHL------AILDHPYREIMKLCENCPSCPRILGLTASILN 211
>gi|29294651 dicer1 [Homo sapiens]
Length = 1922
Score = 41.6 bits (96), Expect = 0.008
Identities = 47/223 (21%), Positives = 95/223 (42%), Gaps = 28/223 (12%)
Query: 448 PALKPKPFGSEEQLLPVEK-------LPKYAQAGFEGFKTLNRIQSKLYRAALETDENLL 500
PAL+P + + P LP +A + T + Q +L AAL D N +
Sbjct: 4 PALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAAL--DHNTI 61
Query: 501 LCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSF----G 556
+C TG+GKT +A++ + +E+ I G + + + +++ + V + V +
Sbjct: 62 VCLNTGSGKTFIAVL-LTKELSYQIR--GDFSRNGKRTVFLVNSANQVAQQVSAVRTHSD 118
Query: 557 KRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQL--VRLIIL 614
++ Y + + +E + Q+++ T + + G Y L + L++
Sbjct: 119 LKVGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNG----YLSLSDINLLVF 174
Query: 615 DEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPN 657
DE HL +L+ ++ E R++GL+A++ N
Sbjct: 175 DECHL------AILDHPYREIMKLCENCPSCPRILGLTASILN 211
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sapiens]
Length = 648
Score = 40.4 bits (93), Expect = 0.019
Identities = 44/146 (30%), Positives = 71/146 (48%), Gaps = 11/146 (7%)
Query: 1318 ESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEF-AILRMLLQSS-EGR 1375
E++ + F PIQ+Q + V D + V A TG+GKT+C + ++LQ S +G+
Sbjct: 255 ENIKKAGFQKPTPIQSQAWPIVLQGIDLIGV-AQTGTGKTLCYLMPGFIHLVLQPSLKGQ 313
Query: 1376 -----CVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKG-NIIISTP 1429
+ +TP LA QV + + L V G ++ L KG +III+TP
Sbjct: 314 RNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATP 373
Query: 1430 EKWDILSRRWKQRKNVQNINLFVVDE 1455
+ + L + N++NI V+DE
Sbjct: 374 GRLNDL--QMSNFVNLKNITYLVLDE 397
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 40.0 bits (92), Expect = 0.024
Identities = 44/206 (21%), Positives = 85/206 (41%), Gaps = 28/206 (13%)
Query: 124 LGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDD--TRYHVLVNLGKKITD 181
L + D L ++E + K + D E+ + D Q++D R L K + +
Sbjct: 517 LAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDE 576
Query: 182 YGGDKEIQN--MDDNIDETYGVNVQFE--------------------SDEEEGDEDVYGE 219
G +KE+ +D ++E N +FE SDE+E +ED Y +
Sbjct: 577 EGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEK 636
Query: 220 VREEASDDDMEGDEAVVRCTLSANLVA----SGELMSSKKKDLHPRDIDAFWLQRQLSRF 275
V ++ SD+ + + A + +A+ A + E + + D D D ++ +
Sbjct: 637 VFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKL 696
Query: 276 YDDAIVSQKKADEVLEILKTASDDRE 301
++D ++K DE + + DD +
Sbjct: 697 FEDDDSNEKLFDEEEDSSEKLFDDSD 722
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 40.0 bits (92), Expect = 0.024
Identities = 44/206 (21%), Positives = 85/206 (41%), Gaps = 28/206 (13%)
Query: 124 LGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDD--TRYHVLVNLGKKITD 181
L + D L ++E + K + D E+ + D Q++D R L K + +
Sbjct: 517 LAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDE 576
Query: 182 YGGDKEIQN--MDDNIDETYGVNVQFE--------------------SDEEEGDEDVYGE 219
G +KE+ +D ++E N +FE SDE+E +ED Y +
Sbjct: 577 EGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEK 636
Query: 220 VREEASDDDMEGDEAVVRCTLSANLVA----SGELMSSKKKDLHPRDIDAFWLQRQLSRF 275
V ++ SD+ + + A + +A+ A + E + + D D D ++ +
Sbjct: 637 VFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKL 696
Query: 276 YDDAIVSQKKADEVLEILKTASDDRE 301
++D ++K DE + + DD +
Sbjct: 697 FEDDDSNEKLFDEEEDSSEKLFDDSD 722
>gi|149408122 RNA helicase LGP2 [Homo sapiens]
Length = 678
Score = 39.7 bits (91), Expect = 0.032
Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 19/180 (10%)
Query: 481 LNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIY 540
L Q ++ ALE +N+++ PTGAGKT A R + VD K++
Sbjct: 3 LRSYQWEVIMPALE-GKNIIIWLPTGAGKTRAAAYVAKRHLE---------TVDGAKVVV 52
Query: 541 IAPMRSLVQEMVGSFGKRLATYGITVAELTGD---HQLCKEEISATQIIVCTPEKWDIIT 597
+ LV + F +R+ TV L+GD +++CT E +
Sbjct: 53 LVNRVHLVTQHGEEF-RRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMAL 111
Query: 598 RKGGERTYTQLV--RLIILDEIHLLHDDRGPVLEALVARAIR-NIEMTQEDVRLIGLSAT 654
E + +L LI++DE H H D V ++++ + ++ Q +++GL+A+
Sbjct: 112 TSPEEEEHVELTVFSLIVVDECHHTHKD--TVYNVIMSQYLELKLQRAQPLPQVLGLTAS 169
>gi|18093112 ABT1-associated protein [Homo sapiens]
Length = 851
Score = 39.7 bits (91), Expect = 0.032
Identities = 86/422 (20%), Positives = 162/422 (38%), Gaps = 60/422 (14%)
Query: 62 QMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKT-------KETRETYE 114
+ ++E + K E++ D++ G + + PK K +E
Sbjct: 112 EKKKETKKANHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKN 171
Query: 115 VLLSFIQAALGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDL---LLGQTDDTRYH- 170
++ ++L ++ R + G ++ ++K+ ++ + R+E+ L+ D Y
Sbjct: 172 IVQHTTDSSLEEKQRTLDSGTSE----IVKSPRIECSKTRREMQSVVQLIMTRDSDGYEN 227
Query: 171 ----------VLVNLGKKITDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEV 220
L + +++ G D+E +N ++ G + E DEEE +++ E
Sbjct: 228 STDGEMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDE--EED 285
Query: 221 REEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKDLHPRDIDAFWLQRQLSRFYDDAI 280
+E S+DD + D N+ S E DL P + R+L +
Sbjct: 286 EDEDSEDDDKSDSGPDLARGKGNIETSSE-DEDDTADLFPEESGFEHAWRELDK------ 338
Query: 281 VSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSE 340
+ADE+ L + D + LL FN+F + + +++ + SE
Sbjct: 339 -DAPRADEITRRLAVCNMDWDRLKAKDLLALFNSF-------KPKGGVIFSVKI--YPSE 388
Query: 341 AEKERIMGKMEADP-ELSKFLYQLHETEKEDLIREERSRRERVRQ---SRMDTDLETMDL 396
KER+ + P EL ED ++ + RE++R R+ +D
Sbjct: 389 FGKERMKEEQVQGPVELLSI--------PEDAPEKDWTSREKLRDYQFKRLKYYYAVVDC 440
Query: 397 DQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGY-EEVHVPALKPKPF 455
D A + D + L F F+ + R D +F + K EV++ A KPK F
Sbjct: 441 D--SPETASKIYEDCDGLEFESSCSFI-DLRFIPDDITFDDEPKDVASEVNLTAYKPKYF 497
Query: 456 GS 457
S
Sbjct: 498 TS 499
>gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I
[Homo sapiens]
Length = 925
Score = 39.3 bits (90), Expect = 0.042
Identities = 30/125 (24%), Positives = 55/125 (44%), Gaps = 10/125 (8%)
Query: 497 ENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFG 556
+N ++CAPTG GKT V+L+ + K K+++ A + ++ F
Sbjct: 258 KNTIICAPTGCGKTFVSLLICEHHLKKF------PQGQKGKVVFFANQIPVYEQQKSVFS 311
Query: 557 KRLATYGITVAELTG---DHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLII 613
K +G V ++G ++ ++ + II+ TP+ + K G + L+I
Sbjct: 312 KYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQIL-VNNLKKGTIPSLSIFTLMI 370
Query: 614 LDEIH 618
DE H
Sbjct: 371 FDECH 375
Score = 35.8 bits (81), Expect = 0.46
Identities = 39/154 (25%), Positives = 67/154 (43%), Gaps = 34/154 (22%)
Query: 1345 NVFVGAPTGSGKT-----ICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQD 1399
N + APTG GKT IC L+ Q +G+ V+ + EQ + K+ +
Sbjct: 259 NTIICAPTGCGKTFVSLLICEHH--LKKFPQGQKGKVVFFANQIPVYEQ-QKSVFSKYFE 315
Query: 1400 RLNKKVVLLTGETSTDL---KLLGKGNIIISTPEKWDILSRRWKQR--KNVQNINLFVVD 1454
R +V ++G T+ ++ +++ +III TP+ IL K+ ++ L + D
Sbjct: 316 RHGYRVTGISGATAENVPVEQIVENNDIIILTPQ---ILVNNLKKGTIPSLSIFTLMIFD 372
Query: 1455 EVH------------------LIGGENGPVLEVI 1470
E H +GG +GP+ +VI
Sbjct: 373 ECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVI 406
>gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]
Length = 2048
Score = 39.3 bits (90), Expect = 0.042
Identities = 54/239 (22%), Positives = 94/239 (39%), Gaps = 36/239 (15%)
Query: 433 GSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFE--GFKT---------- 480
G+ R Q G + +PA S++ +L V Q E GF T
Sbjct: 28 GTERPQSPGSSKAPLPAAAEAQLESDDDVLLVAAYEAERQLCLENGGFCTSAGALWIYPT 87
Query: 481 ---LNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFK 537
+ Q + RAAL N L+C PTG GKT +A + M K
Sbjct: 88 NCPVRDYQLHISRAALFC--NTLVCLPTGLGKTFIAAVVMYNFYRW---------FPSGK 136
Query: 538 IIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLC--KEEISATQIIVCTPEKWDI 595
++++AP + LV + + + + + +AE+TG Q KE + +++ TP+
Sbjct: 137 VVFMAPTKPLVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEIWCSKRVLFLTPQVMVN 196
Query: 596 ITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSAT 654
+G ++ +++DE H + + +R + R++ LSAT
Sbjct: 197 DLSRGA--CPAAEIKCLVIDEAHKALGNYA------YCQVVRELVKYTNHFRILALSAT 247
Score = 32.0 bits (71), Expect = 6.7
Identities = 36/151 (23%), Positives = 62/151 (41%), Gaps = 11/151 (7%)
Query: 1345 NVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKK 1404
N V PTG GKT A + G+ V++ P + L Q Y+
Sbjct: 106 NTLVCLPTGLGKTFIAAVVMYNFYRWFPSGKVVFMAPTKPLVTQQIEACYQ-VMGIPQSH 164
Query: 1405 VVLLTGET--STDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE 1462
+ +TG T ST ++ ++ TP+ +++ + I V+DE H G
Sbjct: 165 MAEMTGSTQASTRKEIWCSKRVLFLTPQV--MVNDLSRGACPAAEIKCLVIDEAHKALG- 221
Query: 1463 NGPVLEVICSRMRYISSQIERPIRIVALSSS 1493
N +V+ ++Y + RI+ALS++
Sbjct: 222 NYAYCQVVRELVKYTNH-----FRILALSAT 247
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,280,357
Number of Sequences: 37866
Number of extensions: 3436226
Number of successful extensions: 11301
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 10847
Number of HSP's gapped (non-prelim): 393
length of query: 2136
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2018
effective length of database: 13,779,330
effective search space: 27806687940
effective search space used: 27806687940
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.