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Search of human proteins with 40068061
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40068061 centromere protein Q [Homo sapiens]
(268 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40068061 centromere protein Q [Homo sapiens] 516 e-147
gi|151101140 coiled-coil domain containing 2 isoform a [Homo sap... 50 3e-06
gi|151105223 coiled-coil domain containing 2 isoform a [Homo sap... 50 3e-06
gi|151105229 coiled-coil domain containing 2 isoform a [Homo sap... 50 3e-06
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 48 1e-05
gi|71061468 centromere protein E [Homo sapiens] 47 1e-05
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 47 1e-05
gi|4503593 epidermal growth factor receptor pathway substrate 15... 47 2e-05
gi|229577185 epidermal growth factor receptor pathway substrate ... 46 3e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 45 5e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 45 9e-05
gi|55770834 centromere protein F [Homo sapiens] 45 9e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 44 2e-04
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 43 3e-04
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 42 4e-04
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 42 4e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 42 6e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 42 6e-04
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 42 6e-04
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 42 6e-04
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 42 7e-04
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 41 0.001
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 41 0.001
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 41 0.001
gi|33188443 microfilament and actin filament cross-linker protei... 41 0.001
gi|33188445 microfilament and actin filament cross-linker protei... 41 0.001
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 41 0.001
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 41 0.001
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 41 0.001
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 41 0.001
>gi|40068061 centromere protein Q [Homo sapiens]
Length = 268
Score = 516 bits (1330), Expect = e-147
Identities = 268/268 (100%), Positives = 268/268 (100%)
Query: 1 MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNL 60
MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNL
Sbjct: 1 MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNL 60
Query: 61 KHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQ 120
KHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQ
Sbjct: 61 KHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQ 120
Query: 121 CETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLK 180
CETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLK
Sbjct: 121 CETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLK 180
Query: 181 NKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLK 240
NKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLK
Sbjct: 181 NKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLK 240
Query: 241 DLDILHNSSQMKSMSTFIEEAYKKLDAS 268
DLDILHNSSQMKSMSTFIEEAYKKLDAS
Sbjct: 241 DLDILHNSSQMKSMSTFIEEAYKKLDAS 268
>gi|151101140 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 49.7 bits (117), Expect = 3e-06
Identities = 53/262 (20%), Positives = 116/262 (44%), Gaps = 38/262 (14%)
Query: 22 KKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTR 81
K DN+E+ E ++ +T +K ++++ + ++ + + ++ L K
Sbjct: 313 KDDNQEIASMERQLTDTKEKINQFIEEI------RQLDMDLEEHQGEMNQKYKELKKR-E 365
Query: 82 DHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLL 141
+H+ T +E+ T + +K K +I+ ++ LL+ C + + + +SS+
Sbjct: 366 EHMDTFIETFEET-KNQELKRKAQIEANI----VALLEHCS------RNINRIEQISSIT 414
Query: 142 NMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLK---NKIQILASEVEEEEE--- 195
N E K ++ L E+ K T + +T +IQ L+ K+++L S++ EE+
Sbjct: 415 NQEL---KMMQDDLNFKSTEVQKSQSTAQNLTSDIQRLQLDLQKMELLESKMTEEQHSLK 471
Query: 196 -RVKQMHQ----------INSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDI 244
++KQM + SSG + +L Q+ + T + ++ QN + L
Sbjct: 472 SKIKQMTTDLEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIMEKQNIEYEALKT 531
Query: 245 LHNSSQMKSMSTFIEEAYKKLD 266
++ S T +E ++ L+
Sbjct: 532 QLQENETHSQLTNLERKWQHLE 553
>gi|151105223 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 49.7 bits (117), Expect = 3e-06
Identities = 53/262 (20%), Positives = 116/262 (44%), Gaps = 38/262 (14%)
Query: 22 KKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTR 81
K DN+E+ E ++ +T +K ++++ + ++ + + ++ L K
Sbjct: 313 KDDNQEIASMERQLTDTKEKINQFIEEI------RQLDMDLEEHQGEMNQKYKELKKR-E 365
Query: 82 DHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLL 141
+H+ T +E+ T + +K K +I+ ++ LL+ C + + + +SS+
Sbjct: 366 EHMDTFIETFEET-KNQELKRKAQIEANI----VALLEHCS------RNINRIEQISSIT 414
Query: 142 NMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLK---NKIQILASEVEEEEE--- 195
N E K ++ L E+ K T + +T +IQ L+ K+++L S++ EE+
Sbjct: 415 NQEL---KMMQDDLNFKSTEVQKSQSTAQNLTSDIQRLQLDLQKMELLESKMTEEQHSLK 471
Query: 196 -RVKQMHQ----------INSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDI 244
++KQM + SSG + +L Q+ + T + ++ QN + L
Sbjct: 472 SKIKQMTTDLEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIMEKQNIEYEALKT 531
Query: 245 LHNSSQMKSMSTFIEEAYKKLD 266
++ S T +E ++ L+
Sbjct: 532 QLQENETHSQLTNLERKWQHLE 553
>gi|151105229 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 49.7 bits (117), Expect = 3e-06
Identities = 53/262 (20%), Positives = 116/262 (44%), Gaps = 38/262 (14%)
Query: 22 KKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTR 81
K DN+E+ E ++ +T +K ++++ + ++ + + ++ L K
Sbjct: 313 KDDNQEIASMERQLTDTKEKINQFIEEI------RQLDMDLEEHQGEMNQKYKELKKR-E 365
Query: 82 DHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLL 141
+H+ T +E+ T + +K K +I+ ++ LL+ C + + + +SS+
Sbjct: 366 EHMDTFIETFEET-KNQELKRKAQIEANI----VALLEHCS------RNINRIEQISSIT 414
Query: 142 NMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLK---NKIQILASEVEEEEE--- 195
N E K ++ L E+ K T + +T +IQ L+ K+++L S++ EE+
Sbjct: 415 NQEL---KMMQDDLNFKSTEVQKSQSTAQNLTSDIQRLQLDLQKMELLESKMTEEQHSLK 471
Query: 196 -RVKQMHQ----------INSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDI 244
++KQM + SSG + +L Q+ + T + ++ QN + L
Sbjct: 472 SKIKQMTTDLEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIMEKQNIEYEALKT 531
Query: 245 LHNSSQMKSMSTFIEEAYKKLD 266
++ S T +E ++ L+
Sbjct: 532 QLQENETHSQLTNLERKWQHLE 553
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 47.8 bits (112), Expect = 1e-05
Identities = 59/244 (24%), Positives = 114/244 (46%), Gaps = 27/244 (11%)
Query: 20 KRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKS 79
K K + E ++ + V++ + K + LK+ SE + ++ + GK A + K
Sbjct: 843 KVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKEN---QKGKAAILDL---EKTCKE 896
Query: 80 TRDHLQTMMESVI--MTILSNSI-KEKE---EIQYHLNFLKKRLLQQCETLKVPPKKMED 133
+ LQ ME+ + L S+ KEKE +++ LN ++++L+Q TLK K+ +
Sbjct: 897 LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQ 956
Query: 134 LT-NVSSLLNMERARDK-----ANEEGLALLQ--EEIDKMVETTELMTGNIQSLKNKIQI 185
L N++ L + K E +A+LQ E +K+ + + + K KI +
Sbjct: 957 LQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISV 1016
Query: 186 LASEVEEEEERVKQM----HQINSSGVLSLPELSQKTLKAPTLQKEILA---LIPNQNAL 238
L + E+ +E KQ+ + S + + +L K Q+++++ I NQN L
Sbjct: 1017 LQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKL 1076
Query: 239 LKDL 242
+++L
Sbjct: 1077 IQEL 1080
Score = 35.8 bits (81), Expect = 0.040
Identities = 45/216 (20%), Positives = 99/216 (45%), Gaps = 19/216 (8%)
Query: 26 EEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGK-------TAASKRKTWQPLSK 78
E+V K++N + +K ++L + Q + +L+ + T+ ++ + SK
Sbjct: 575 EQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESK 634
Query: 79 STRDHLQTMMESVIMTILSNSIK---EKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLT 135
L +++ +LS ++ ++Q HL+ + L + + L K L
Sbjct: 635 EKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELN---KITTQLD 691
Query: 136 NVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLK-NKIQILASEVEEEE 194
V++ L ++ E L +E+ + + TE + G I+ L+ + +++ AS+ E+
Sbjct: 692 QVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASK-EQAL 750
Query: 195 ERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILA 230
+ ++Q Q+N+ L ELS K ++KEI++
Sbjct: 751 QDLQQQRQLNTDLELRATELS----KQLEMEKEIVS 782
Score = 28.9 bits (63), Expect = 4.9
Identities = 37/178 (20%), Positives = 79/178 (44%), Gaps = 14/178 (7%)
Query: 27 EVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQT 86
E++ + +++ +K +DL S K + + + T + S LQ
Sbjct: 1041 ELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQE 1100
Query: 87 MMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLN---M 143
+++ S+KEKE + +K L + E +K +K ++T ++ L +
Sbjct: 1101 RCKALQDIQKEKSLKEKELVN------EKSKLAEIEEIKCRQEK--EITKLNEELKSHKL 1152
Query: 144 ERARDKAN--EEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQ 199
E ++ N + L+Q++++ + L Q +N+ QIL +V++EEE +K+
Sbjct: 1153 ESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQ-QILKDQVKKEEEELKK 1209
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 47.4 bits (111), Expect = 1e-05
Identities = 47/216 (21%), Positives = 93/216 (43%), Gaps = 24/216 (11%)
Query: 13 QQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKH------GKTA 66
++L+ N K ++ EE+ ++ K +++LK + + KH LK K
Sbjct: 1329 ERLRLNEKFQESQEEI--------KSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQ 1380
Query: 67 ASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEE----IQYHLNFLKKRLLQQCE 122
S+ K Q L+ +D+ T + S + K K+ I+ + L KRL + +
Sbjct: 1381 ESQSKQEQSLNMKEKDNETTKIVSEM-----EQFKPKDSALLRIEIEMLGLSKRLQESHD 1435
Query: 123 TLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNK 182
+K K+ +DL + +L E + K N + + E ++ ++ + N+
Sbjct: 1436 EMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINE 1495
Query: 183 IQILASEVEEEEERV-KQMHQINSSGVLSLPELSQK 217
+++ SE E E + KQ+ IN + E+ +K
Sbjct: 1496 LRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEK 1531
Score = 45.1 bits (105), Expect = 7e-05
Identities = 56/246 (22%), Positives = 106/246 (43%), Gaps = 27/246 (10%)
Query: 27 EVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQT 86
++VL EN+ N + +LS E Q ++L KT S + Q L + TR+ +
Sbjct: 834 KMVLEENERMN------QEIVNLSKEAQKFDSSLGALKTELSYKT--QELQEKTREVQER 885
Query: 87 MME-SVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMER 145
+ E + L N + ++ + ++L Q E +K ++ +DL + L +ER
Sbjct: 886 LNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIER 945
Query: 146 ARDKANEEGLALL----QEEIDKMVETTELMTGNIQSLKNKIQILAS---EVEEEEERVK 198
+ K++ + QE++ +E+ + I +LK+KI S +EE K
Sbjct: 946 DQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETK 1005
Query: 199 QMHQINSSGVLSLPELSQKTLKAPTL----------QKEILALIPNQNALLKDLD-ILHN 247
Q G+ +L K + T Q++I +LI +N L + L+ ++
Sbjct: 1006 DEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAE 1065
Query: 248 SSQMKS 253
Q+K+
Sbjct: 1066 KEQLKT 1071
Score = 44.3 bits (103), Expect = 1e-04
Identities = 59/276 (21%), Positives = 119/276 (43%), Gaps = 32/276 (11%)
Query: 9 KKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHL--KDLSSE---------GQTKH 57
K+ +QQL+ ++ + +E + K N ++ KN L K+L+ E Q +
Sbjct: 1130 KEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLN 1189
Query: 58 TNLKHGKTAASKRKTWQPLSKS---TRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLK 114
N + K+ +RK + L KS RDHL+ I I + ++ KEE++ LK
Sbjct: 1190 ENYEEVKSITKERKVLKELQKSFETERDHLR----GYIREIEATGLQTKEELKIAHIHLK 1245
Query: 115 KRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTG 174
+ E + +K + N L E++ K EE + +L EE + + E+
Sbjct: 1246 EHQETIDELRRSVSEKTAQIINTQDL---EKSHTKLQEE-IPVLHEEQELLPNVKEV--S 1299
Query: 175 NIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPN 234
Q N++++L + ++ ++ + + SQ+ +K+ T +++ N
Sbjct: 1300 ETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERD------N 1353
Query: 235 QNALLKDLDILHNSSQMKSMSTF--IEEAYKKLDAS 268
+ + L++ H+ + T I+E+ K + S
Sbjct: 1354 LKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQS 1389
Score = 43.5 bits (101), Expect = 2e-04
Identities = 59/268 (22%), Positives = 106/268 (39%), Gaps = 54/268 (20%)
Query: 41 KNKNHLKDLSSEGQTKHTNLKHG------KTAASKRKTWQPLSKSTRDHLQTMMESVIMT 94
K K +K + Q + LK K S+ K +Q L + + Q M +
Sbjct: 1590 KEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEI--- 1646
Query: 95 ILSNSIKEKEEIQYHLNF---------LKKRLLQQCETLKVPPKKMEDLTNVSSLLNMER 145
+KE+ E Q LN L + L + E ++ K+ +DL +V L +ER
Sbjct: 1647 ---EHLKEQFETQ-KLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVER 1702
Query: 146 -----------ARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVE--- 191
RD +E L ++ + + ET + + G + N+I + ++E
Sbjct: 1703 DQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSN 1762
Query: 192 ----------EEEERVKQMHQINSSGVLSLPE--LSQKTLKAPTLQKEILALIPNQNALL 239
+EE R+ MH + +S+KT K +QK+ + N NA L
Sbjct: 1763 DALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKD----LENSNAKL 1818
Query: 240 KD--LDILHNSSQMKSMSTFIEEAYKKL 265
++ ++ N Q+ ++ + E KK+
Sbjct: 1819 QEKIQELKANEHQLITLKKDVNETQKKV 1846
Score = 35.4 bits (80), Expect = 0.053
Identities = 56/252 (22%), Positives = 103/252 (40%), Gaps = 26/252 (10%)
Query: 9 KKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAAS 68
+ + QLK N K E+V + +K LK+ NL +T S
Sbjct: 1455 QSESDQLKENIK------EIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEIS 1508
Query: 69 KRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFL---KKRLLQQCETLK 125
T Q ++ D LQ ++ + +IK+ E+Q +N L K+ + L+
Sbjct: 1509 ---TIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQ 1565
Query: 126 VPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQI 185
KM +LTN R + ++E + ++ +E ++M E + LK +
Sbjct: 1566 SIESKMLELTN----------RLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKE 1615
Query: 186 LASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAP-TLQKEILALIPNQNALLKDLDI 244
+ ++++E +E+ Q ++ + + LK QK L I +N L I
Sbjct: 1616 IVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRL--TQI 1673
Query: 245 LH-NSSQMKSMS 255
LH N +M+S++
Sbjct: 1674 LHENLEEMRSVT 1685
Score = 32.7 bits (73), Expect = 0.34
Identities = 57/277 (20%), Positives = 117/277 (42%), Gaps = 30/277 (10%)
Query: 10 KNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHL--KDLSSEGQTK--HTNLKHGKT 65
+N ++++ K + D V + R+ +K+N +DL + + K H +LK +
Sbjct: 1676 ENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQE 1735
Query: 66 AASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLK 125
K + + ++Q +E + + +K +EE++ LK++ +
Sbjct: 1736 TIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRG 1795
Query: 126 VPPKKMEDLTNVSSLLNMERARD-------KANEEGLALLQEEIDKMVETTELMTGNIQS 178
+ +K + L+N+ L A+ KANE L L++++++ T+ ++
Sbjct: 1796 IVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNE----TQKKVSEMEQ 1851
Query: 179 LKNKIQ---ILASEVEEEEERVKQMHQINSSGVLSLPE------LSQKTLKAPTLQ-KEI 228
LK +I+ + S++E E + Q N + S+ + ++TLK Q KE
Sbjct: 1852 LKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKES 1911
Query: 229 LALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKL 265
L Q +DL+I + +S +E KL
Sbjct: 1912 L-----QETKARDLEIQQELKTARMLSKEHKETVDKL 1943
Score = 32.7 bits (73), Expect = 0.34
Identities = 37/192 (19%), Positives = 79/192 (41%), Gaps = 9/192 (4%)
Query: 10 KNAQQLKRNPKRKKDNEEVVLSENKVR-NTVKKNKNHLKDLSSEGQTKHTNLKHGKTAAS 68
K A+ L + K D +SE ++ + ++K+ + KD E Q K L+ +
Sbjct: 1927 KTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKD---ELQKKIQELQKKELQLL 1983
Query: 69 KRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPP 128
+ K +S + ++ + + LS + Q L K+L + E +++
Sbjct: 1984 RVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQ-----LTKKLHESLEEIRIVA 2038
Query: 129 KKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILAS 188
K+ ++L + L MER + A + + ++ L++ Q L ++ S
Sbjct: 2039 KERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCS 2098
Query: 189 EVEEEEERVKQM 200
++E +R +M
Sbjct: 2099 RIKELLKRYSEM 2110
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 47.4 bits (111), Expect = 1e-05
Identities = 63/298 (21%), Positives = 133/298 (44%), Gaps = 45/298 (15%)
Query: 4 KANASKKNAQQLKRNP----KRKKDNEEVVLSE--NKVRNTVKKNKNHLKDLSSEGQTKH 57
K +K+ A Q+++N K +++EE+ +E K+R T + + +++ S + + H
Sbjct: 419 KLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHH 478
Query: 58 TNLKHG--------------KTAASKRKTWQPLSKSTRDHLQTMMESV------IMTILS 97
+K +T +K K + T D L E + I +L
Sbjct: 479 AKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLL- 537
Query: 98 NSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLAL 157
+ +K +++Q L +R Q+ E LK +++E L ++ + L + + E L L
Sbjct: 538 DKVKTADQLQEQL----QRGKQEIENLK---EEVESLNSLINDLQKDIEGSRKRESELLL 590
Query: 158 LQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQK 217
E + + + ++QS +K+ S+++ + E++KQ + S +L EL ++
Sbjct: 591 FTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKE 650
Query: 218 TLKAPTLQKEILALIPNQNALLKDLDIL---------HNSSQMKSMSTFIEEAYKKLD 266
++ TLQ E+ AL ++ L ++S +K ++ +++A +KLD
Sbjct: 651 EVQ--TLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLD 706
Score = 31.6 bits (70), Expect = 0.76
Identities = 43/183 (23%), Positives = 74/183 (40%), Gaps = 16/183 (8%)
Query: 23 KDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRD 82
K +VL E V++ + ++ +K L E + KH L + K + L K T
Sbjct: 186 KGEHALVLFEKCVQDKYLQQEHIIKKLIKENK-KHQEL-FVDICSEKDNLREELKKRTET 243
Query: 83 HLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLN 142
Q M N+IK+ E LN K Q V K +
Sbjct: 244 EKQHM----------NTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQR 293
Query: 143 MERARDK---ANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQ 199
ME+A K A +E A++ + + E+ +L ++L+ K++ E+E+ ++KQ
Sbjct: 294 MEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEK-ETLEKKLRDANKELEKNTNKIKQ 352
Query: 200 MHQ 202
+ Q
Sbjct: 353 LSQ 355
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 46.6 bits (109), Expect = 2e-05
Identities = 40/186 (21%), Positives = 87/186 (46%), Gaps = 27/186 (14%)
Query: 20 KRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKS 79
+R+K+N E L E + +T+K+ + ++DL E Q ++TNL+ K A K++
Sbjct: 346 QREKNNVEQDLKEKE--DTIKQRTSEVQDLQDEVQRENTNLQ--KLQAQKQQ-------- 393
Query: 80 TRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSS 139
+ +L ++K +++ L ++K+ ++ + + K E + S
Sbjct: 394 ------------VQELLDELDEQKAQLEEQLKEVRKKCAEEAQLIS--SLKAELTSQESQ 439
Query: 140 LLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQ 199
+ E KA EE L+ LQ+E ++ E+ E ++ L+ +Q E+ + ++ +
Sbjct: 440 ISTYEEELAKAREE-LSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLME 498
Query: 200 MHQINS 205
M + +
Sbjct: 499 MKDLEN 504
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 46.2 bits (108), Expect = 3e-05
Identities = 40/185 (21%), Positives = 86/185 (46%), Gaps = 27/185 (14%)
Query: 21 RKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKST 80
R+K+N E L E + +T+K+ + ++DL E Q ++TNL+ K A K++
Sbjct: 33 REKNNVEQDLKEKE--DTIKQRTSEVQDLQDEVQRENTNLQ--KLQAQKQQ--------- 79
Query: 81 RDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSL 140
+ +L ++K +++ L ++K+ ++ + + K E + S +
Sbjct: 80 -----------VQELLDELDEQKAQLEEQLKEVRKKCAEEAQLIS--SLKAELTSQESQI 126
Query: 141 LNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQM 200
E KA EE L+ LQ+E ++ E+ E ++ L+ +Q E+ + ++ +M
Sbjct: 127 STYEEELAKAREE-LSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEM 185
Query: 201 HQINS 205
+ +
Sbjct: 186 KDLEN 190
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 45.4 bits (106), Expect = 5e-05
Identities = 55/233 (23%), Positives = 103/233 (44%), Gaps = 23/233 (9%)
Query: 1 MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNL 60
M+ + A K+N + + KR D+ E+ L+ KV +N +K+LS E N+
Sbjct: 936 MNSELVAKKRNLEDKCSSLKRDIDDLELTLT--KVEKEKHATENKVKNLSEEMTALEENI 993
Query: 61 KHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTI------------LSNSIKEKEEIQY 108
++K+ Q + T D LQ + V I L S++++++++
Sbjct: 994 SK---LTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRA 1050
Query: 109 HLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVET 168
L K++L LK+ + + DL N + E+ + K E L+ LQ +ID
Sbjct: 1051 DLERAKRKLEGD---LKMSQESIMDLENDKQQIE-EKLKKKEFE--LSQLQAKIDDEQVH 1104
Query: 169 TELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKA 221
+ I+ L+ +I+ L E+E E ++ + S L E+S++ +A
Sbjct: 1105 SLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEA 1157
Score = 43.9 bits (102), Expect = 1e-04
Identities = 44/197 (22%), Positives = 90/197 (45%), Gaps = 28/197 (14%)
Query: 9 KKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAAS 68
++ ++L R+ R+K+ EE ++S + +N DL + Q++ NL +
Sbjct: 861 ERTKEELARSEARRKELEEKMVSLLQEKN----------DLQLQVQSETENLMDAEERC- 909
Query: 69 KRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPP 128
+ L KS + ++E+ + L+ ++E+EE+ L K+ L +C +LK
Sbjct: 910 -----EGLIKS-----KILLEAKVKE-LTERLEEEEEMNSELVAKKRNLEDKCSSLK--- 955
Query: 129 KKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILAS 188
D+ ++ L A E + L EE+ + E +T +SL+ Q
Sbjct: 956 ---RDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLD 1012
Query: 189 EVEEEEERVKQMHQINS 205
+++ EE++V + +IN+
Sbjct: 1013 DLQVEEDKVNGLIKINA 1029
Score = 38.1 bits (87), Expect = 0.008
Identities = 53/221 (23%), Positives = 94/221 (42%), Gaps = 39/221 (17%)
Query: 7 ASKKNAQQLKRNPKR-------KKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTN 59
AS + Q++ N KR ++D EE L T++K + D +E + N
Sbjct: 1157 ASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ---ADSVAELGEQIDN 1213
Query: 60 LKHGKTAASKRKTW------------QPLSKSTRDHLQTMMESVIMTILS--NSIKEKEE 105
L+ K K K+ + LSKS ++ +E T+ + IK K+E
Sbjct: 1214 LQRVKQKLEKEKSELKMEIDDMASNIEALSKS-----KSNIERTCRTVEDQFSEIKAKDE 1268
Query: 106 IQ----YHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEE 161
Q + LN K RL Q L ++ E L +S L ++A + EE L+ +
Sbjct: 1269 QQTQLIHDLNMQKARLQTQNGELSHRVEEKESL--ISQLTKSKQALTQQLEE----LKRQ 1322
Query: 162 IDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQ 202
+++ + M +QS ++ +L + EEE+E ++ +
Sbjct: 1323 MEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQR 1363
Score = 37.0 bits (84), Expect = 0.018
Identities = 47/166 (28%), Positives = 73/166 (43%), Gaps = 13/166 (7%)
Query: 109 HLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGL-ALLQEEIDKMV- 166
+L F K LL+ E K ED L AR K EE + +LLQE+ D +
Sbjct: 835 NLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQ 894
Query: 167 ---ETTELMTGNIQS---LKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLK 220
ET LM + +K+KI +L ++V+E ER+++ ++NS V L K
Sbjct: 895 VQSETENLMDAEERCEGLIKSKI-LLEAKVKELTERLEEEEEMNSELVAKKRNLED---K 950
Query: 221 APTLQKEILALIPNQNALLKDLDILHNS-SQMKSMSTFIEEAYKKL 265
+L+++I L + K+ N + T +EE KL
Sbjct: 951 CSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKL 996
Score = 31.2 bits (69), Expect = 0.99
Identities = 31/199 (15%), Positives = 83/199 (41%), Gaps = 18/199 (9%)
Query: 16 KRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQP 75
+RN ++ EE+ ++ + T + ++ L D S Q H+ ++ +K+K
Sbjct: 1680 RRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHS--QNTSLINTKKKLEAD 1737
Query: 76 LSKSTRDHLQTMMES-----------VIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETL 124
+++ + ++ ES +++ +K++++ HL +KK L Q + L
Sbjct: 1738 IAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1797
Query: 125 KVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQ 184
+ + E L +++ ++ E L+ E+D + + K++
Sbjct: 1798 QHRLDEAEQLALKGGKKQIQKLENRVRE-----LENELDVEQKRGAEALKGAHKYERKVK 1852
Query: 185 ILASEVEEEEERVKQMHQI 203
+ + EE+ + + ++ +
Sbjct: 1853 EMTYQAEEDHKNILRLQDL 1871
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 44.7 bits (104), Expect = 9e-05
Identities = 49/242 (20%), Positives = 103/242 (42%), Gaps = 20/242 (8%)
Query: 32 ENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGK---TAASKRKTWQPLSKSTRDHLQTMM 88
E+ + ++++NKN KDL+ + + KH K K KT K +D L T
Sbjct: 573 ESSLEKSLQENKNQSKDLAVHLEAEKN--KHNKEITVMVEKHKTELESLKHQQDALWTEK 630
Query: 89 ESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARD 148
V+ K++ Q + L+++ Q+ ETL + K++ ++ + +
Sbjct: 631 LQVL----------KQQYQTEMEKLREKCEQEKETL-LKDKEIIFQAHIEEMNEKTLEKL 679
Query: 149 KANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGV 208
+ L L E+ ++++ + + LK++ + E+E + + K HQ +
Sbjct: 680 DVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSI 739
Query: 209 LSLPELS----QKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKK 264
+ E+S +K LK Q E+L +++ + + + +K +++A K
Sbjct: 740 IKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAK 799
Query: 265 LD 266
LD
Sbjct: 800 LD 801
Score = 37.0 bits (84), Expect = 0.018
Identities = 49/240 (20%), Positives = 101/240 (42%), Gaps = 41/240 (17%)
Query: 7 ASKKNAQQLKRNPKRKKDNEEVVLSENKVRNT--VKKNKNHLKDLSSEGQTKHTNLKHGK 64
A +K+ + + + K+ E + L E +++ + +++N L+DL E +T T +
Sbjct: 514 ALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILE-- 571
Query: 65 TAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETL 124
+ES + L + + +++ HL K + ++ T+
Sbjct: 572 -----------------------LESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEI-TV 607
Query: 125 KVPPKKMEDLTNVSSLLNMERARDKANEEGLALL----QEEIDKMVETTELMTGNIQSLK 180
V K E L +++ +D E L +L Q E++K+ E E + LK
Sbjct: 608 MVEKHKTE-------LESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETL--LK 658
Query: 181 NKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLK 240
+K I + +EE E+ + + + + SL + LKA +E L+++ +Q +K
Sbjct: 659 DKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMK 718
Score = 35.4 bits (80), Expect = 0.053
Identities = 60/258 (23%), Positives = 109/258 (42%), Gaps = 43/258 (16%)
Query: 22 KKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTR 81
+K +EE +S + + VK+ + SSE Q H K A K + ++
Sbjct: 445 EKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRE 504
Query: 82 DHLQTMMESVIMTILSNSIK---EKEEIQ----YHLNFLKKRLLQQCETLKVPPKKMEDL 134
Q M+ + S +K EKE+ + L KK +L + E K+ + E
Sbjct: 505 REFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESEN-KLRDLQQEAE 563
Query: 135 TNVSSLLNMERARDKANEEG------LALLQE--------EIDKMVETTELMTGNIQSLK 180
T + +L +E + +K+ +E LA+ E EI MVE + ++SLK
Sbjct: 564 TYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKT---ELESLK 620
Query: 181 N--------KIQILASEVEEEEERVKQMHQINSSGVLS---------LPELSQKTL-KAP 222
+ K+Q+L + + E E++++ + +L + E+++KTL K
Sbjct: 621 HQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLD 680
Query: 223 TLQKEILALIPNQNALLK 240
Q E+ +L + +LK
Sbjct: 681 VKQTELESLSSELSEVLK 698
Score = 33.9 bits (76), Expect = 0.15
Identities = 51/256 (19%), Positives = 108/256 (42%), Gaps = 40/256 (15%)
Query: 39 VKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSN 98
+++ K L+ + S+ Q K + A R+ Q + + + HLQ ++
Sbjct: 167 LQREKKKLQGILSQSQDKSL-----RRIAELREELQ-MDQQAKKHLQEEFDA-------- 212
Query: 99 SIKEKEE----IQYHLNFLKKRLLQ---QCETLKVPPKKMEDLTNVSSLLNMERARDKAN 151
S++EK++ +Q ++ LK+RL + LK P+ + N E +
Sbjct: 213 SLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVV 272
Query: 152 EEG-----LALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVE----------EEEER 196
E+G L LQ+ + + + IQS K + +L SE E +E E+
Sbjct: 273 EDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEK 332
Query: 197 VKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIP----NQNALLKDLDILHNSSQMK 252
+K +H + +++ ++ ++ K ++ ++ +K+ +I S++K
Sbjct: 333 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIK 392
Query: 253 SMSTFIEEAYKKLDAS 268
M+T EE ++ + S
Sbjct: 393 QMTTQGEELREQKEKS 408
Score = 33.5 bits (75), Expect = 0.20
Identities = 42/224 (18%), Positives = 96/224 (42%), Gaps = 28/224 (12%)
Query: 22 KKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTR 81
KK+ E + + ++ +K+ K + LS + + L++ + + K L K
Sbjct: 1345 KKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYD 1404
Query: 82 DHLQTMMESV------IMTILSNSIKEKEEIQYHLNFLKK-------RLLQQCETLKVPP 128
+ +++ V + T+ I E++ N + R Q T+K
Sbjct: 1405 EEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQ 1464
Query: 129 KKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQ---- 184
++E L + A +K +E + LL+EE+D+ + + + G ++ K+K++
Sbjct: 1465 IQLE--------LKSKEAYEK--DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKES 1514
Query: 185 ILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEI 228
L +E++ + R+ ++ + + + L++ LK QK+I
Sbjct: 1515 NLETELKSQTARIMELEDHITQKTIEIESLNE-VLKNYNQQKDI 1557
Score = 32.0 bits (71), Expect = 0.58
Identities = 52/268 (19%), Positives = 113/268 (42%), Gaps = 22/268 (8%)
Query: 6 NASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEG-QTKHTNLKHGK 64
+A K Q L + + +K N E+ E KV++ + ++ L+D + E QTK ++
Sbjct: 857 DAHKIQVQDLMQ--QLEKQNSEM---EQKVKSLTQVYESKLEDGNKEQEQTKQILVEKEN 911
Query: 65 TAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETL 124
R+ + + L +S+ + + E+ E ++ K ++ E +
Sbjct: 912 MILQMREGQKKEIEILTQKLSAKEDSI------HILNEEYETKF------KNQEKKMEKV 959
Query: 125 KVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQ 184
K K+M++ L + + + L L Q+E + E+ N + + +
Sbjct: 960 KQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVS 1019
Query: 185 ILASEVEEEEERVKQMHQINSSGVLSLPE--LSQKTLKAPTLQKEILALIPNQNALLKDL 242
L + +E+ E + ++H+ + V+S+ E L+Q+ + + + L + A LK
Sbjct: 1020 RLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQK 1079
Query: 243 DILH--NSSQMKSMSTFIEEAYKKLDAS 268
+L +M T+++E K D +
Sbjct: 1080 ILLFGCEKEEMNKEITWLKEEGVKQDTT 1107
Score = 31.6 bits (70), Expect = 0.76
Identities = 39/202 (19%), Positives = 82/202 (40%), Gaps = 21/202 (10%)
Query: 20 KRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSE----------GQTKHTNLKHGKTAASK 69
+++K +E+V + +R K+++ L+ L E + + LKH T
Sbjct: 1938 EKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 1997
Query: 70 RKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPK 129
+ + L+ ++ I + E Q N L K++ ++ + LK K
Sbjct: 1998 MREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAK 2057
Query: 130 KMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTE--------LMTGNIQSLKN 181
+ E++ + + RD + L LQ++ + +E E +M Q +
Sbjct: 2058 RYEEILDAREEEMTAKVRDLQTQ--LEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQK 2115
Query: 182 KIQILASEVEEEEERVKQMHQI 203
I S+++E+E R +Q+H +
Sbjct: 2116 TTLISDSKLKEQEFR-EQIHNL 2136
Score = 30.0 bits (66), Expect = 2.2
Identities = 52/252 (20%), Positives = 104/252 (41%), Gaps = 26/252 (10%)
Query: 27 EVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLK--HGKTAASKRKTWQPLSKSTRDHL 84
EV+ + +K+ + K+ + E + K K H + S K + + T L
Sbjct: 695 EVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKAL 754
Query: 85 QTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNME 144
+ + + + +L K +E Q H+ L+ + + L+ K++ + S + +
Sbjct: 755 KDQINQLEL-LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQ 813
Query: 145 RARDKANEEGLALLQEEIDKMVETTELMTGNIQSLK------------NKIQI------L 186
KA EE LA LQ+++ + L+T + ++ +KIQ+ L
Sbjct: 814 T---KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQL 870
Query: 187 ASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILH 246
+ E E++VK + Q+ S L Q+ K ++KE + ++ + K+++IL
Sbjct: 871 EKQNSEMEQKVKSLTQVYES-KLEDGNKEQEQTKQILVEKENM-ILQMREGQKKEIEILT 928
Query: 247 NSSQMKSMSTFI 258
K S I
Sbjct: 929 QKLSAKEDSIHI 940
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 44.7 bits (104), Expect = 9e-05
Identities = 47/202 (23%), Positives = 90/202 (44%), Gaps = 41/202 (20%)
Query: 22 KKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTR 81
KK + +K+ T K++K L L + + ++ LK KT S W KS
Sbjct: 575 KKREHHIEQLNDKLSKTEKESKALLSALELK-KKEYEELKEEKTLFS---CW----KSEN 626
Query: 82 DHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQ----------CETLKVPPKKM 131
+ L T MES EKE +Q +N L+ L Q TL++ + +
Sbjct: 627 EKLLTQMES-----------EKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENL 675
Query: 132 E-DLTNVSSLLNMERARDKANEEGLALLQE-----------EIDKMVETTELMTGNIQSL 179
++ N+ ++L+ + + + LQ+ EI+ M T +TG ++ L
Sbjct: 676 SVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDL 735
Query: 180 KNKIQILASEVEEEEERVKQMH 201
++K+Q+L++E+ +++ + +H
Sbjct: 736 EHKLQLLSNEIMDKDRCYQDLH 757
Score = 40.4 bits (93), Expect = 0.002
Identities = 54/280 (19%), Positives = 119/280 (42%), Gaps = 37/280 (13%)
Query: 4 KANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHG 63
K + +K++Q L K + E + NK + + K L+ SE + N+
Sbjct: 2036 KLQSLEKDSQALSLT---KCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKA 2092
Query: 64 KTAASKRKTWQPLS-KSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCE 122
AA K L ST++ + + + E+++ + +K+ L E
Sbjct: 2093 LEAALVEKGEFALRLSSTQEEVHQLRRGI------------EKLRVRIEADEKKQLHIAE 2140
Query: 123 TLKVPPKKMEDLTNVSSLLNMERARDKANEEGLAL-----------LQEEIDKMVETTEL 171
LK ++ + L + L E + N+E + L L+ +I++M + ++
Sbjct: 2141 KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKV 2200
Query: 172 MTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILAL 231
++ +L+++ + L +++E++ ++ ++ ++ SS L E Q ++ K + +
Sbjct: 2201 FELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEM 2260
Query: 232 IPNQ--------NALLKDLDILHNSSQMKSMSTFIEEAYK 263
+ NQ AL D +I+ + Q S+ IEE ++
Sbjct: 2261 LQNQLKELNEAVAALCGDQEIMKATEQ--SLDPPIEEEHQ 2298
Score = 39.3 bits (90), Expect = 0.004
Identities = 56/244 (22%), Positives = 105/244 (43%), Gaps = 38/244 (15%)
Query: 22 KKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTR 81
+K+ E+ + E + V+ +N LK+L+ A + Q + K+T
Sbjct: 2242 EKEQAEIQIKEES-KTAVEMLQNQLKELNE--------------AVAALCGDQEIMKATE 2286
Query: 82 DHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLL 141
L +E L NSI E+++ L +K+ L + LK + L L
Sbjct: 2287 QSLDPPIEEEHQ--LRNSI---EKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENL 2341
Query: 142 NMERARDKANEEGLALLQEEIDKMVET--------TELMTG---NIQSLKNKIQILASEV 190
E + N+E AL E VET T+ + G ++ +++++ + L +E+
Sbjct: 2342 ERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNEL 2401
Query: 191 EEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLD----ILH 246
++E+ER+ ++ INSS L E Q+ ++ + ++ Q LK+L+ LH
Sbjct: 2402 QKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQ---LKELNERVAALH 2458
Query: 247 NSSQ 250
N +
Sbjct: 2459 NDQE 2462
Score = 36.2 bits (82), Expect = 0.031
Identities = 41/197 (20%), Positives = 86/197 (43%), Gaps = 21/197 (10%)
Query: 85 QTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNME 144
Q+ S I+ +S++ E Q +N L +QCE L ++E+ N+ M
Sbjct: 820 QSPKNSAILQNRVDSLEFSLESQKQMN---SDLQKQCEELVQIKGEIEE--NLMKAEQMH 874
Query: 145 RARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQIN 204
++ + ++ LQE+ +++ + ++Q+L +VE E+ ++++ + N
Sbjct: 875 QSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSN 934
Query: 205 SSGVLSLPELS--QKTLKAP--------TLQKEILALIPNQNALLKDLDILHNSSQM--- 251
SL EL +TL +L K + + +N LK+++ N +M
Sbjct: 935 HLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLI 994
Query: 252 ---KSMSTFIEEAYKKL 265
+S + +I+E K +
Sbjct: 995 QKSESFANYIDEREKSI 1011
Score = 35.4 bits (80), Expect = 0.053
Identities = 55/269 (20%), Positives = 120/269 (44%), Gaps = 29/269 (10%)
Query: 18 NPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAAS--------- 68
N ++K+ E+V + E K ++ + LK+L+ H + + K
Sbjct: 2420 NILQEKEQEKVQMKE-KSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECL 2478
Query: 69 ---KRKTWQPLSKSTRDH--LQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCET 123
K + Q L ++ ++ LQ+ + +I + + ++ E+ ++ LK ++ Q E
Sbjct: 2479 ELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEV-EDGKQKLEKKDEEISRLKNQIQDQ-EQ 2536
Query: 124 LKVPPKKMEDLTNVSSLLNME-RARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNK 182
L ++E + N+E R E+ + +LQ + + +T E++ + ++L+N+
Sbjct: 2537 LVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENE 2596
Query: 183 IQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDL 242
+++ + E+V +M + + E++QKT + LQ+E L +N L +L
Sbjct: 2597 LELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAE---LQEE---LSGEKNRLAGEL 2650
Query: 243 DIL-----HNSSQMKSMSTFIEEAYKKLD 266
+L + Q+K ++ E K LD
Sbjct: 2651 QLLLEEIKSSKDQLKELTLENSELKKSLD 2679
Score = 31.6 bits (70), Expect = 0.76
Identities = 41/147 (27%), Positives = 69/147 (46%), Gaps = 17/147 (11%)
Query: 132 EDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVE 191
E+L+ V+S N R + L + +KM E T+ + + + IQ+ +EV+
Sbjct: 1951 EELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVK 2010
Query: 192 EEEERVKQMHQINSSGVLSLPELSQKT---LKAPTLQKEILAL------IPNQNALL-KD 241
E+ E ++ + SS V L L KT K +L+K+ AL + NQ A L K+
Sbjct: 2011 EKTELLQTL----SSDVSEL--LKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKE 2064
Query: 242 LDILHNSSQMKSMSTFIEEAYKKLDAS 268
++L S+ + E Y+KL+ S
Sbjct: 2065 KELLVKESE-SLQARLSESDYEKLNVS 2090
Score = 28.9 bits (63), Expect = 4.9
Identities = 60/283 (21%), Positives = 127/283 (44%), Gaps = 38/283 (13%)
Query: 3 GKANASKKNAQQLKRNPKRKKDNEEVV--LSENKVRNTVKKNKN-HLKDLSSEGQTKHTN 59
GK KK+ +++ R + +D E++V LS+ + + + K +N L++L+ E + K
Sbjct: 2513 GKQKLEKKD-EEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQV 2571
Query: 60 LKHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQ 119
L+ AS + T + L S ++ L+ +E M +S K + K +
Sbjct: 2572 LQSKN--ASLQDTLEVLQSSYKN-LENELELTKMDKMSFVEK-----------VNKMTAK 2617
Query: 120 QCETLKVPPKKMEDLTNVSSLLNMERARDKANEEG-LALLQEEIDKMVETTELMTGNIQS 178
+ E ++M ++ ++ L E + +K G L LL EEI + + +T
Sbjct: 2618 ETEL----QREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSE 2673
Query: 179 LKNKIQILASEVEEEEERVKQ--------MHQINSS-GVLSLPELSQKTLKAPTLQKEIL 229
LK + + + E+E +V++ +H+ L L Q ++ T ++++
Sbjct: 2674 LKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLT 2733
Query: 230 ALIPNQNALLKDLDILHNSSQ-----MKSMSTFIEEAYK-KLD 266
+ ++ ++D+L +S + +K+ + +EE K K+D
Sbjct: 2734 SKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMD 2776
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 43.5 bits (101), Expect = 2e-04
Identities = 40/213 (18%), Positives = 102/213 (47%), Gaps = 20/213 (9%)
Query: 26 EEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQ 85
EE + ++++ VK+ + ++ E + KH L K +++ + + + ++
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 86 TMMESV------IMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSS 139
+ + I+ L + ++E+EE L KK++ + L+ +++++
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLE---EQLDEEEGARQ 967
Query: 140 LLNMER----ARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEE 195
L +E+ A+ K EE + LL+++ K ++ +LM +++I +S++ EEEE
Sbjct: 968 KLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM-------EDRIAECSSQLAEEEE 1020
Query: 196 RVKQMHQINSSGVLSLPELSQKTLKAPTLQKEI 228
+ K + +I + + + +L ++ K ++E+
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQEL 1053
Score = 28.9 bits (63), Expect = 4.9
Identities = 36/182 (19%), Positives = 80/182 (43%), Gaps = 30/182 (16%)
Query: 7 ASKKNAQQLKRNPKRK--KDNEEVVLSENKVRNTVK-KNKNHLKDLSSE-GQTKHTNLKH 62
A++++A Q N +++ + N+E+ ++ VK K K + L ++ GQ + +
Sbjct: 1774 AAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQE 1833
Query: 63 GKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCE 122
K A+ K L + T L+ + V E+ + H + K+++ +
Sbjct: 1834 AKERAAANK----LVRRTEKKLKEIFMQV------------EDERRHADQYKEQMEKANA 1877
Query: 123 TLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNK 182
+K +++E+ ++ N R + LQ E+D E E ++ + +LKN+
Sbjct: 1878 RMKQLKRQLEEAEEEATRANASRRK----------LQRELDDATEANEGLSREVSTLKNR 1927
Query: 183 IQ 184
++
Sbjct: 1928 LR 1929
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 42.7 bits (99), Expect = 3e-04
Identities = 41/198 (20%), Positives = 95/198 (47%), Gaps = 12/198 (6%)
Query: 76 LSKSTRDHLQTMMESVIMTILS-NSIKEKEEIQ-YHLNFLKKRLLQQCETLKVPPKK--- 130
L + + +Q+ E++ +L + EK ++ +L + + Q C ++ +K
Sbjct: 842 LLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKC 901
Query: 131 -MEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASE 189
+++ N+ LL + RD+ E L LL++ + K +++ L+ KI+ L E
Sbjct: 902 FIKEHENLKPLLEQKELRDRRAE--LILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKE 959
Query: 190 VEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDL-DILHNS 248
+E+EE++ ++I V + EL + T+++E+ +L ++ L + D++ +
Sbjct: 960 CKEKEEKI---NKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGA 1016
Query: 249 SQMKSMSTFIEEAYKKLD 266
K++ E+ ++LD
Sbjct: 1017 ESYKNLLLEYEKQSEQLD 1034
Score = 35.4 bits (80), Expect = 0.053
Identities = 24/108 (22%), Positives = 57/108 (52%), Gaps = 2/108 (1%)
Query: 97 SNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVS-SLLNMERARDKANEEGL 155
+ ++ E EE+Q L KK+L + + L++ K + T ++ + + ER + N++ L
Sbjct: 1118 ATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQK-L 1176
Query: 156 ALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQI 203
+I+ + + ++ ++L+ +I L S V++ EE+ ++ Q+
Sbjct: 1177 TNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQL 1224
Score = 32.0 bits (71), Expect = 0.58
Identities = 45/212 (21%), Positives = 95/212 (44%), Gaps = 21/212 (9%)
Query: 69 KRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPP 128
K +T Q +++++ M + V ++ KE Q H+N++K+ + E + V
Sbjct: 85 KAETEQQCLSLKKENIK-MKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRS 143
Query: 129 KKMEDLTNVSSLLN---------MERARDKAN-EEGLALLQEEIDKMVETTELMTGNIQS 178
K ED N+ L E+ + + N E+ + LQEEI+K+ E I
Sbjct: 144 KYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFE---EQILY 200
Query: 179 LKNKIQILASEVEEEEERVKQMHQINSSGV-LSLPELSQKTLKAPTL-QKEILALIPNQN 236
L+ ++ E +E +++ + + NS ++ L ++ L+ + Q+E+ L+
Sbjct: 201 LQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIE 260
Query: 237 ALLKDLDILHNSSQMKSMSTFIEEAYKKLDAS 268
A K+ + +++ ++ E K+ +AS
Sbjct: 261 ASAKE-----HEAEINKLNELKENLVKQCEAS 287
Score = 30.8 bits (68), Expect = 1.3
Identities = 42/212 (19%), Positives = 96/212 (45%), Gaps = 25/212 (11%)
Query: 27 EVVLSENKVRNTVKKN-KNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQ 85
E+ ++K+ +K + + H + LS+ Q + + A +++ T +S + +
Sbjct: 1269 EITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVH 1328
Query: 86 TMME-----SVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSL 140
+++ S+ + +E+E ++ ++ LK +L L++ NVS L
Sbjct: 1329 NVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQI---------NVSEL 1379
Query: 141 LNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQM 200
++ D E +LQE + K E E + S++++ ++ SE + ++
Sbjct: 1380 QTLQSEHDTLLERHNKMLQETVSKEAELRE----KLCSIQSENMMMKSEHTQTVSQLTSQ 1435
Query: 201 HQI--NS--SGVLSLPELSQKTLKAPTLQKEI 228
+++ NS V L E +KT++ TLQ+++
Sbjct: 1436 NEVLRNSFRDQVRHLQEEHRKTVE--TLQQQL 1465
Score = 29.3 bits (64), Expect = 3.8
Identities = 49/228 (21%), Positives = 99/228 (43%), Gaps = 27/228 (11%)
Query: 18 NPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLK--HGKTAASKRKTWQP 75
N K E V EN ++N +KN +L LS + T LK GK + +
Sbjct: 544 NEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQ----RDTMLKELEGKINSLTEEKDDF 599
Query: 76 LSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLT 135
++K H + + N K+ E + + L K++ Q + +K+ +LT
Sbjct: 600 INKLKNSHEE----------MDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELT 649
Query: 136 NVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEE 195
L + +D+ N++ L L ++ + E E+++ ++SL + L+SE +++
Sbjct: 650 --GGLEETLKEKDQ-NDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSE-KKQLS 705
Query: 196 RVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLD 243
R ++ V+ ++Q L+K++ ++ Q+ L K L+
Sbjct: 706 RDLEVFLSQKEDVILKEHITQ-------LEKKLQLMVEEQDNLNKLLE 746
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 42.4 bits (98), Expect = 4e-04
Identities = 56/259 (21%), Positives = 115/259 (44%), Gaps = 32/259 (12%)
Query: 9 KKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAAS 68
+K +L ++ ++K+ EE ++ T+ + KN DL + Q + NL +
Sbjct: 858 QKTKDELAKSEAKRKELEEKLV-------TLVQEKN---DLQLQVQAESENLLDAEERCD 907
Query: 69 KRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPP 128
+ L K+ + +E+ I + + +++EEI L K++L +C LK
Sbjct: 908 Q------LIKA-----KFQLEAKIKEVTERA-EDEEEINAELTAKKRKLEDECSELK--- 952
Query: 129 KKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILAS 188
K ++DL + + E+ A E + L EE+ + ET +T ++L+ Q
Sbjct: 953 KDIDDLELTLAKVEKEK---HATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALD 1009
Query: 189 EVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNS 248
+++ EE++V +++ S + +L + L+ + L N+ L DL + S
Sbjct: 1010 DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVD---LERNKRKLEGDLKLAQES 1066
Query: 249 -SQMKSMSTFIEEAYKKLD 266
+++ ++E KK D
Sbjct: 1067 ILDLENDKQQLDERLKKKD 1085
Score = 33.9 bits (76), Expect = 0.15
Identities = 48/192 (25%), Positives = 83/192 (43%), Gaps = 28/192 (14%)
Query: 20 KRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKS 79
K ++D EE L + ++K H ++ G+ + NL+ K K K+ L
Sbjct: 1174 KLRRDLEEATLQHEAMVAALRKK--HADSVAELGE-QIDNLQRVKQKLEKEKSEFKLEI- 1229
Query: 80 TRDHLQTMMESV---------IMTILSNSIKE----KEEIQYHLNFL---KKRLLQQCET 123
D L + MESV I L + + E EEIQ L+ L K RL +
Sbjct: 1230 --DDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGE 1287
Query: 124 LKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKI 183
L ++ E + VS L ++A + EE L+ ++++ + + +QS ++
Sbjct: 1288 LSRQLEEKESI--VSQLSRSKQAFTQQTEE----LKRQLEEENKAKNALAHALQSSRHDC 1341
Query: 184 QILASEVEEEEE 195
+L + EEE+E
Sbjct: 1342 DLLREQYEEEQE 1353
Score = 32.7 bits (73), Expect = 0.34
Identities = 46/212 (21%), Positives = 89/212 (41%), Gaps = 21/212 (9%)
Query: 22 KKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTR 81
KKD +++ L+ KV +N +K+L+ E + ++K Q +
Sbjct: 952 KKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAK---LTREKKALQEAHQQAL 1008
Query: 82 DHLQTMMESVI------------MTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPK 129
D LQ + V + L +S++++++++ L K++L LK+ +
Sbjct: 1009 DDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGD---LKLAQE 1065
Query: 130 KMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASE 189
+ DL N L+ ER + K E LQ +++ I+ L+ +I+ L E
Sbjct: 1066 SILDLENDKQQLD-ERLKKKDFE--YCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEE 1122
Query: 190 VEEEEERVKQMHQINSSGVLSLPELSQKTLKA 221
+E E + + S L ELS++ +A
Sbjct: 1123 IEAERATRAKTEKQRSDYARELEELSERLEEA 1154
Score = 31.6 bits (70), Expect = 0.76
Identities = 33/168 (19%), Positives = 78/168 (46%), Gaps = 9/168 (5%)
Query: 67 ASKRKTWQPLSKSTRDHLQTMMESVIMTILSNS--IKEKEEIQYHLNFLKKRLL----QQ 120
A K + + L ++ + ++TM ++ + S + I+ K++++ LN ++ +L Q
Sbjct: 1578 AEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQA 1637
Query: 121 CETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLK 180
ETLK L + L+ + +E LA+++ + + E + ++ +
Sbjct: 1638 AETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE 1697
Query: 181 NKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEI 228
++ E+ + ERV+ +H N+S + + +L ++ LQ E+
Sbjct: 1698 RARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQ---LQSEV 1742
Score = 30.0 bits (66), Expect = 2.2
Identities = 30/180 (16%), Positives = 76/180 (42%), Gaps = 17/180 (9%)
Query: 25 NEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHL 84
N ++ ++ K+ + + ++ ++D S + + K T A+ + T HL
Sbjct: 1721 NTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1780
Query: 85 QTMMESVIMTI--LSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLN 142
+ M +++ T+ L + + E E++ K+ +Q+ ET + + L
Sbjct: 1781 ERMKKNLEQTVKDLQHRLDEAEQLALKGG---KKQIQKLET---------RIRELEFELE 1828
Query: 143 MERARDKANEEGLALLQEEIDKMVETTELMTGNI---QSLKNKIQILASEVEEEEERVKQ 199
E+ ++ + +GL + + ++ +E N+ Q L +K+Q+ + + E +
Sbjct: 1829 GEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADE 1888
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 42.4 bits (98), Expect = 4e-04
Identities = 58/241 (24%), Positives = 105/241 (43%), Gaps = 34/241 (14%)
Query: 21 RKKDNEEVVLSENK-VRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKS 79
R KD E+ ENK + TV + L L E + H +L+ K + + + +
Sbjct: 584 RMKDVEK----ENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAKEKGERAEKLERELQR 639
Query: 80 TRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVS- 138
++ + V T L + ++ E +++ + L + TL+ K ++ L NVS
Sbjct: 640 LQEENGRLARKV--TSLETATEKVEALEHE----SQGLQLENRTLR---KSLDTLQNVSL 690
Query: 139 SLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEE------ 192
L +ER + + E L E+ ++VET + + ++ + Q L E EE
Sbjct: 691 QLEGLERDNKQLDAENL-----ELRRLVETMRFTSTKLAQMERENQQLEREKEELRKNVD 745
Query: 193 -------EEERVKQMHQINSSGVLSLPE-LSQKTLKAPTLQKEILALIPNQNALLKDLDI 244
+ ER++ +Q S+ L L + L + K TL+ E+ L + AL +DL+
Sbjct: 746 LLKALGKKSERLELSYQSVSAENLRLQQSLESSSHKTQTLESELGELEAERQALRRDLEA 805
Query: 245 L 245
L
Sbjct: 806 L 806
Score = 36.2 bits (82), Expect = 0.031
Identities = 45/210 (21%), Positives = 91/210 (43%), Gaps = 28/210 (13%)
Query: 69 KRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPP 128
K +T K + L+T+ E +I +EKE++Q + LK +Q + L
Sbjct: 512 KLQTQLEREKQSNQDLETLSEELI--------REKEQLQSDMETLKADKARQIKDL---- 559
Query: 129 KKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILAS 188
++ +D N ++ ++ ++E + +++E + +T G + L+ + + L
Sbjct: 560 EQEKDHLN-RAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHR 618
Query: 189 EVEEEEER----------VKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNAL 238
++E+ +E+ ++++ + N + L T K L+ E L L
Sbjct: 619 DLEQAKEKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEALEHESQGLQLENRTL 678
Query: 239 LKDLDILHN-SSQMKSMSTFIEEAYKKLDA 267
K LD L N S Q++ +E K+LDA
Sbjct: 679 RKSLDTLQNVSLQLEG----LERDNKQLDA 704
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 42.0 bits (97), Expect = 6e-04
Identities = 63/286 (22%), Positives = 116/286 (40%), Gaps = 29/286 (10%)
Query: 2 SGKANASKKNAQQLKRNPKRKKDNE----EVVLSENKVRNTVKKNKNHLKDLSSEGQTKH 57
S + NASK + K N + K E E+V + ++N +K+ +K+ + +T
Sbjct: 485 SVEGNASKILKME-KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Query: 58 TNLKHG----KTAASKRKTWQPLSKSTRDHLQTMMESVIMTI------LSNSIKEKEEIQ 107
T ++ K + + S R Q E+ + I L SIKE
Sbjct: 544 TLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKL 603
Query: 108 YHLNFLKKRLLQQCETLKVPPKKMEDLTN-------VSSLLNMERARDKANEEGLALLQE 160
+ F K+++ ++ E K ++ E+L N + LL + K E + L++
Sbjct: 604 SKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQ 663
Query: 161 EIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLK 220
E ++ + + S KN L ++E E+ Q+ + N ++ L ++K
Sbjct: 664 ENSELERENRKLKKTLDSFKN----LTFQLESLEKENSQLDEENLELRRNVESLKCASMK 719
Query: 221 APTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLD 266
LQ E L + L K L++L S + +E +Y+ LD
Sbjct: 720 MAQLQLENKELESEKEQLKKGLELLKASFKKTER---LEVSYQGLD 762
Score = 37.4 bits (85), Expect = 0.014
Identities = 51/274 (18%), Positives = 112/274 (40%), Gaps = 31/274 (11%)
Query: 22 KKDNEEVVLSENKVRNTVKKNKNHLKDLSS----------EGQTKHTNLKHGKTAASKRK 71
+++N E+ K++ T+ KN L S E N++ K A+ K
Sbjct: 662 EQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMA 721
Query: 72 TWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKM 131
Q +K + + + + + S E+ E+ Y ++ + LQ+ TL+ KK+
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK--TLENSNKKI 779
Query: 132 EDLTNVSSLLNMERARDKANEEGLALLQ---EEIDKMVETTELMTGNIQS---------- 178
+ L + L ME + N E L + E+++K ++ E T ++
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Query: 179 -LKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNA 237
L+ + +I + +EE ++ + + N + + + ++ L+KE L+
Sbjct: 840 RLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATI 899
Query: 238 LLKDL-----DILHNSSQMKSMSTFIEEAYKKLD 266
+K L D++ + + M+ +E+ +L+
Sbjct: 900 DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELE 933
Score = 35.8 bits (81), Expect = 0.040
Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 35/265 (13%)
Query: 9 KKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSE--------GQTKHTNL 60
KK + K +R ++ E + K ++K +LK + + + N
Sbjct: 614 KKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENR 673
Query: 61 KHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIK-----------EKEEIQYH 109
K KT S + L +++ Q E++ + S+K E +E++
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733
Query: 110 LNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETT 169
LKK L E LK KK E L L++E R LQ+ ++ +
Sbjct: 734 KEQLKKGL----ELLKASFKKTERLEVSYQGLDIENQR----------LQKTLENSNKKI 779
Query: 170 ELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEIL 229
+ + +Q L+ + Q L +EE + K++ Q+ E SQ L+KE
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Query: 230 ALIPNQNALLKDLDILHNSSQMKSM 254
L Q A +KD + N+ ++ ++
Sbjct: 840 RL--RQQAEIKDTTLEENNVKIGNL 862
Score = 35.8 bits (81), Expect = 0.040
Identities = 43/191 (22%), Positives = 84/191 (43%), Gaps = 30/191 (15%)
Query: 78 KSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNV 137
+ST D ++ES + + L S++ KE E + ++E+ TN
Sbjct: 947 QSTDDSRYKLLESKLESTLKKSLEIKE-----------------EKIAALEARLEESTNY 989
Query: 138 SSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERV 197
+ L E K N E L Q+E ++MV+++ ++G + + Q E+ + ++R+
Sbjct: 990 NQQLRQELKTVKKNYEALKQRQDE-ERMVQSSPPISGEDNKWERESQETTRELLKVKDRL 1048
Query: 198 KQMHQINSS----GVLSLPELSQKTLKAPTLQKEILAL------IPNQNALL--KDLDIL 245
++ + N++ +L Q + LQ +ILAL + QN L ++ +
Sbjct: 1049 IEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQ 1108
Query: 246 HNSSQMKSMST 256
+S + S ST
Sbjct: 1109 VENSTLNSQST 1119
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 42.0 bits (97), Expect = 6e-04
Identities = 63/286 (22%), Positives = 116/286 (40%), Gaps = 29/286 (10%)
Query: 2 SGKANASKKNAQQLKRNPKRKKDNE----EVVLSENKVRNTVKKNKNHLKDLSSEGQTKH 57
S + NASK + K N + K E E+V + ++N +K+ +K+ + +T
Sbjct: 485 SVEGNASKILKME-KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Query: 58 TNLKHG----KTAASKRKTWQPLSKSTRDHLQTMMESVIMTI------LSNSIKEKEEIQ 107
T ++ K + + S R Q E+ + I L SIKE
Sbjct: 544 TLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKL 603
Query: 108 YHLNFLKKRLLQQCETLKVPPKKMEDLTN-------VSSLLNMERARDKANEEGLALLQE 160
+ F K+++ ++ E K ++ E+L N + LL + K E + L++
Sbjct: 604 SKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQ 663
Query: 161 EIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLK 220
E ++ + + S KN L ++E E+ Q+ + N ++ L ++K
Sbjct: 664 ENSELERENRKLKKTLDSFKN----LTFQLESLEKENSQLDEENLELRRNVESLKCASMK 719
Query: 221 APTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLD 266
LQ E L + L K L++L S + +E +Y+ LD
Sbjct: 720 MAQLQLENKELESEKEQLKKGLELLKASFKKTER---LEVSYQGLD 762
Score = 37.4 bits (85), Expect = 0.014
Identities = 51/274 (18%), Positives = 112/274 (40%), Gaps = 31/274 (11%)
Query: 22 KKDNEEVVLSENKVRNTVKKNKNHLKDLSS----------EGQTKHTNLKHGKTAASKRK 71
+++N E+ K++ T+ KN L S E N++ K A+ K
Sbjct: 662 EQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMA 721
Query: 72 TWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKM 131
Q +K + + + + + S E+ E+ Y ++ + LQ+ TL+ KK+
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK--TLENSNKKI 779
Query: 132 EDLTNVSSLLNMERARDKANEEGLALLQ---EEIDKMVETTELMTGNIQS---------- 178
+ L + L ME + N E L + E+++K ++ E T ++
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Query: 179 -LKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNA 237
L+ + +I + +EE ++ + + N + + + ++ L+KE L+
Sbjct: 840 RLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATI 899
Query: 238 LLKDL-----DILHNSSQMKSMSTFIEEAYKKLD 266
+K L D++ + + M+ +E+ +L+
Sbjct: 900 DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELE 933
Score = 35.8 bits (81), Expect = 0.040
Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 35/265 (13%)
Query: 9 KKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSE--------GQTKHTNL 60
KK + K +R ++ E + K ++K +LK + + + N
Sbjct: 614 KKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENR 673
Query: 61 KHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIK-----------EKEEIQYH 109
K KT S + L +++ Q E++ + S+K E +E++
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733
Query: 110 LNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETT 169
LKK L E LK KK E L L++E R LQ+ ++ +
Sbjct: 734 KEQLKKGL----ELLKASFKKTERLEVSYQGLDIENQR----------LQKTLENSNKKI 779
Query: 170 ELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEIL 229
+ + +Q L+ + Q L +EE + K++ Q+ E SQ L+KE
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Query: 230 ALIPNQNALLKDLDILHNSSQMKSM 254
L Q A +KD + N+ ++ ++
Sbjct: 840 RL--RQQAEIKDTTLEENNVKIGNL 862
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 42.0 bits (97), Expect = 6e-04
Identities = 55/247 (22%), Positives = 108/247 (43%), Gaps = 15/247 (6%)
Query: 13 QQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHL-KDLSSEGQTKHTNLKHGKTAASKRK 71
QQ + K +K+ EE + +++ K + L K L + + + + + +R+
Sbjct: 389 QQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERRE 448
Query: 72 TW-QPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKK 130
Q L + R + + +L+ +E+EEI LN KK L + E L ++
Sbjct: 449 AAKQELERQRRLEWERIRRQ---ELLNQKNREQEEI-VRLNSKKKNLHLELEALNGKHQQ 504
Query: 131 MEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEV 190
+S L R + + + L +L ++ D + + + +Q +NK+ L E
Sbjct: 505 ------ISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEK 558
Query: 191 EEEEERVKQMHQINS--SGVLSLPELS-QKTLKAPTLQKEILALIPNQNALLKDLDILHN 247
+ ER+K M N+ SGV L + S +K L++++ AL + L ++D +N
Sbjct: 559 QLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNN 618
Query: 248 SSQMKSM 254
+ +M
Sbjct: 619 QLKCGNM 625
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 42.0 bits (97), Expect = 6e-04
Identities = 55/247 (22%), Positives = 108/247 (43%), Gaps = 15/247 (6%)
Query: 13 QQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHL-KDLSSEGQTKHTNLKHGKTAASKRK 71
QQ + K +K+ EE + +++ K + L K L + + + + + +R+
Sbjct: 389 QQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERRE 448
Query: 72 TW-QPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKK 130
Q L + R + + +L+ +E+EEI LN KK L + E L ++
Sbjct: 449 AAKQELERQRRLEWERIRRQ---ELLNQKNREQEEI-VRLNSKKKNLHLELEALNGKHQQ 504
Query: 131 MEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEV 190
+S L R + + + L +L ++ D + + + +Q +NK+ L E
Sbjct: 505 ------ISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEK 558
Query: 191 EEEEERVKQMHQINS--SGVLSLPELS-QKTLKAPTLQKEILALIPNQNALLKDLDILHN 247
+ ER+K M N+ SGV L + S +K L++++ AL + L ++D +N
Sbjct: 559 QLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNN 618
Query: 248 SSQMKSM 254
+ +M
Sbjct: 619 QLKCGNM 625
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 41.6 bits (96), Expect = 7e-04
Identities = 56/247 (22%), Positives = 109/247 (44%), Gaps = 17/247 (6%)
Query: 13 QQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHL-KDLSSEGQTKHTNLKHGKTAASKRK 71
QQ + K +K+ EE + +++ K + L K L + + + + + +R+
Sbjct: 389 QQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERRE 448
Query: 72 TW-QPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKK 130
Q L + R + + +L+ +E+EEI LN KK L + E L ++
Sbjct: 449 AAKQELERQRRLEWERIRRQ---ELLNQKNREQEEI-VRLNSKKKNLHLELEALNGKHQQ 504
Query: 131 MEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEV 190
+S L R + + + L +L ++ D + + + +Q +NK+ L E
Sbjct: 505 ------ISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEK 558
Query: 191 EEEEERVKQMHQINS--SGVLSLPELS-QKTLKAPTLQKEILALIPNQNALLKDLDILHN 247
+ ER+K M N+ SGV L + S +K L++++ AL + L ++D +N
Sbjct: 559 QLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNN 618
Query: 248 SSQMKSM 254
Q+K +
Sbjct: 619 --QLKEL 623
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/158 (22%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 77 SKSTRDHLQTMMESVIMTI--LSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDL 134
++ TR L + + + + L + E+EE + KKRL Q + L+ +E
Sbjct: 931 AEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEA---HLEAE 987
Query: 135 TNVSSLLNMER----ARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEV 190
L +E+ A+ K EE L LL+++ K+ + +L L++++ +S+
Sbjct: 988 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKL-------LEDRLAEFSSQA 1040
Query: 191 EEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEI 228
EEEE+VK ++++ ++ ++ + K ++E+
Sbjct: 1041 AEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1078
Score = 31.2 bits (69), Expect = 0.99
Identities = 39/207 (18%), Positives = 92/207 (44%), Gaps = 24/207 (11%)
Query: 1 MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTV-----KKNKNHLKDL----SS 51
+ G+ A ++ +QL + + + EV E + + T+ KK + L++L +S
Sbjct: 1605 LQGRDEAGEERRRQLAKQLR----DAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1660
Query: 52 EGQTKHTNLKH-GKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHL 110
GQ K +K K A ++ W+ + ++ + ++ S K + ++ +
Sbjct: 1661 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN------RESEKRLKGLEAEV 1714
Query: 111 NFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERA---RDKANEEG-LALLQEEIDKMV 166
L++ L + + +++ + + N+ +A +K EG L L+EE+++
Sbjct: 1715 LRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1774
Query: 167 ETTELMTGNIQSLKNKIQILASEVEEE 193
+EL+ + L +++ L +E+ E
Sbjct: 1775 SNSELLNDRYRKLLLQVESLTTELSAE 1801
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/158 (22%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 77 SKSTRDHLQTMMESVIMTI--LSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDL 134
++ TR L + + + + L + E+EE + KKRL Q + L+ +E
Sbjct: 923 AEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEA---HLEAE 979
Query: 135 TNVSSLLNMER----ARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEV 190
L +E+ A+ K EE L LL+++ K+ + +L L++++ +S+
Sbjct: 980 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKL-------LEDRLAEFSSQA 1032
Query: 191 EEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEI 228
EEEE+VK ++++ ++ ++ + K ++E+
Sbjct: 1033 AEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1070
Score = 31.2 bits (69), Expect = 0.99
Identities = 39/207 (18%), Positives = 92/207 (44%), Gaps = 24/207 (11%)
Query: 1 MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTV-----KKNKNHLKDL----SS 51
+ G+ A ++ +QL + + + EV E + + T+ KK + L++L +S
Sbjct: 1597 LQGRDEAGEERRRQLAKQLR----DAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1652
Query: 52 EGQTKHTNLKH-GKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHL 110
GQ K +K K A ++ W+ + ++ + ++ S K + ++ +
Sbjct: 1653 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN------RESEKRLKGLEAEV 1706
Query: 111 NFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERA---RDKANEEG-LALLQEEIDKMV 166
L++ L + + +++ + + N+ +A +K EG L L+EE+++
Sbjct: 1707 LRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1766
Query: 167 ETTELMTGNIQSLKNKIQILASEVEEE 193
+EL+ + L +++ L +E+ E
Sbjct: 1767 SNSELLNDRYRKLLLQVESLTTELSAE 1793
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/158 (22%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Query: 77 SKSTRDHLQTMMESVIMTI--LSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDL 134
++ TR L + + + + L + E+EE + KKRL Q + L+ +E
Sbjct: 964 AEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEA---HLEAE 1020
Query: 135 TNVSSLLNMER----ARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEV 190
L +E+ A+ K EE L LL+++ K+ + +L L++++ +S+
Sbjct: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKL-------LEDRLAEFSSQA 1073
Query: 191 EEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEI 228
EEEE+VK ++++ ++ ++ + K ++E+
Sbjct: 1074 AEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1111
Score = 31.2 bits (69), Expect = 0.99
Identities = 39/207 (18%), Positives = 92/207 (44%), Gaps = 24/207 (11%)
Query: 1 MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTV-----KKNKNHLKDL----SS 51
+ G+ A ++ +QL + + + EV E + + T+ KK + L++L +S
Sbjct: 1638 LQGRDEAGEERRRQLAKQLR----DAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1693
Query: 52 EGQTKHTNLKH-GKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHL 110
GQ K +K K A ++ W+ + ++ + ++ S K + ++ +
Sbjct: 1694 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN------RESEKRLKGLEAEV 1747
Query: 111 NFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERA---RDKANEEG-LALLQEEIDKMV 166
L++ L + + +++ + + N+ +A +K EG L L+EE+++
Sbjct: 1748 LRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1807
Query: 167 ETTELMTGNIQSLKNKIQILASEVEEE 193
+EL+ + L +++ L +E+ E
Sbjct: 1808 SNSELLNDRYRKLLLQVESLTTELSAE 1834
>gi|33188443 microfilament and actin filament cross-linker protein
isoform b [Homo sapiens]
Length = 5938
Score = 41.2 bits (95), Expect = 0.001
Identities = 57/287 (19%), Positives = 123/287 (42%), Gaps = 39/287 (13%)
Query: 10 KNAQQLKRNP-KRKKDNEEVVLSENK-VRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAA 67
K +QQ K P K + + L EN+ + ++ ++ + + +EG++ ++ G+
Sbjct: 3252 KQSQQAKNCPISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKR 3311
Query: 68 SKRKT-------WQPLSKSTRDHLQTMMESV------------IMTILSNSIKEKEEIQY 108
+ + W+ LSK T D + + + ++ + + + E++
Sbjct: 3312 TLQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELRV 3371
Query: 109 HLN--FLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGL----ALLQEEI 162
L+ L+ LL+ L K+ L ++S ++ +A+E+G+ A + + +
Sbjct: 3372 TLDPVQLESSLLRSKAMLNEVEKRRSLLEILNSAADILINSSEADEDGIRDEKAGINQNM 3431
Query: 163 DKMVETTELMTGNIQSLKNKIQILASEVEEEEERVK-QMHQINSSGVLSLPELSQKTLKA 221
D + E + TG+++ + +++ + E++V+ HQ+ L S K L+
Sbjct: 3432 DAVTEELQAKTGSLEEMTQRLREFQESFKNIEKKVEGAKHQLEIFDALGSQACSNKNLEK 3491
Query: 222 PTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLDAS 268
Q+E+L AL +D L N +Q +E+A DAS
Sbjct: 3492 LRAQQEVL------QALEPQVDYLRNFTQ-----GLVEDAPDGSDAS 3527
Score = 33.9 bits (76), Expect = 0.15
Identities = 33/148 (22%), Positives = 70/148 (47%), Gaps = 15/148 (10%)
Query: 96 LSNSIKEKEEIQYHLN------FLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDK 149
L + +KE + + L+ +LK L ++ ET+ +P + +EDL + +N +A
Sbjct: 3176 LDHEVKEAQTLCDELSVLIGEQYLKDELKKRLETVALPLQGLEDL--AADRINRLQAA-L 3232
Query: 150 ANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVL 209
A+ + + +E+ ++ + + K++ L S+++E EE K ++Q + S +
Sbjct: 3233 ASTQQFQQMFDELRTWLDDKQSQQAKNCPISAKLERLQSQLQENEEFQKSLNQHSGSYEV 3292
Query: 210 SLPELSQKTLKAP------TLQKEILAL 231
+ E L P TLQ +++ L
Sbjct: 3293 IVAEGESLLLSVPPGEEKRTLQNQLVEL 3320
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 41.2 bits (95), Expect = 0.001
Identities = 57/287 (19%), Positives = 123/287 (42%), Gaps = 39/287 (13%)
Query: 10 KNAQQLKRNP-KRKKDNEEVVLSENK-VRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAA 67
K +QQ K P K + + L EN+ + ++ ++ + + +EG++ ++ G+
Sbjct: 2750 KQSQQAKNCPISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKR 2809
Query: 68 SKRKT-------WQPLSKSTRDHLQTMMESV------------IMTILSNSIKEKEEIQY 108
+ + W+ LSK T D + + + ++ + + + E++
Sbjct: 2810 TLQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELRV 2869
Query: 109 HLN--FLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGL----ALLQEEI 162
L+ L+ LL+ L K+ L ++S ++ +A+E+G+ A + + +
Sbjct: 2870 TLDPVQLESSLLRSKAMLNEVEKRRSLLEILNSAADILINSSEADEDGIRDEKAGINQNM 2929
Query: 163 DKMVETTELMTGNIQSLKNKIQILASEVEEEEERVK-QMHQINSSGVLSLPELSQKTLKA 221
D + E + TG+++ + +++ + E++V+ HQ+ L S K L+
Sbjct: 2930 DAVTEELQAKTGSLEEMTQRLREFQESFKNIEKKVEGAKHQLEIFDALGSQACSNKNLEK 2989
Query: 222 PTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLDAS 268
Q+E+L AL +D L N +Q +E+A DAS
Sbjct: 2990 LRAQQEVL------QALEPQVDYLRNFTQ-----GLVEDAPDGSDAS 3025
Score = 33.9 bits (76), Expect = 0.15
Identities = 33/148 (22%), Positives = 70/148 (47%), Gaps = 15/148 (10%)
Query: 96 LSNSIKEKEEIQYHLN------FLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDK 149
L + +KE + + L+ +LK L ++ ET+ +P + +EDL + +N +A
Sbjct: 2674 LDHEVKEAQTLCDELSVLIGEQYLKDELKKRLETVALPLQGLEDL--AADRINRLQAA-L 2730
Query: 150 ANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVL 209
A+ + + +E+ ++ + + K++ L S+++E EE K ++Q + S +
Sbjct: 2731 ASTQQFQQMFDELRTWLDDKQSQQAKNCPISAKLERLQSQLQENEEFQKSLNQHSGSYEV 2790
Query: 210 SLPELSQKTLKAP------TLQKEILAL 231
+ E L P TLQ +++ L
Sbjct: 2791 IVAEGESLLLSVPPGEEKRTLQNQLVEL 2818
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 41.2 bits (95), Expect = 0.001
Identities = 59/274 (21%), Positives = 120/274 (43%), Gaps = 22/274 (8%)
Query: 8 SKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAA 67
+ K +++ K +R D + E + + K KN + + SE + + K K+
Sbjct: 994 NNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK--KEEKSRQ 1051
Query: 68 SKRKTWQPLSKSTRDHLQTM--MESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLK 125
K + L D + + +++ I + K++EE+Q L L + Q+ LK
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1111
Query: 126 VPPKKMEDLTNVSSLLNMER-ARDKANE------EGLALLQEEIDKMVETTELMTGNIQS 178
+ ++++ L+ ER AR+KA + E L L+ E++ +++T
Sbjct: 1112 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1171
Query: 179 LKNKIQILASEVEEE----EERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPN 234
+ ++ +L ++EE E +V++M Q ++ V L E ++ +A + +
Sbjct: 1172 REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1231
Query: 235 QNA-LLKDLDILHNSSQMKSMSTFIEEAYKKLDA 267
+NA L +L +L + Q +E KKL+A
Sbjct: 1232 ENADLAGELRVLGQAKQE------VEHKKKKLEA 1259
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/215 (19%), Positives = 99/215 (46%), Gaps = 19/215 (8%)
Query: 23 KDNEEVVLSENKVRNTVK---KNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKS 79
+ EE+ E++++ T + K +N LK+L + KH+ L K ++ + +
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKEL----EQKHSQLTEEKNLLQEQLQAETELYA 904
Query: 80 TRDHLQTMMESV------IMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMED 133
+ ++ + + I+ + ++E+E+ L +K++ QQ L+ +++E+
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE---EQLEE 961
Query: 134 LTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEE 193
L +E+ +A + L++EI M + ++ + L+ +I L + + EE
Sbjct: 962 EEAARQKLQLEKVTAEAK---IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
Query: 194 EERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEI 228
EE+ K + ++ + + EL + K ++E+
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL 1053
Score = 33.9 bits (76), Expect = 0.15
Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 18/160 (11%)
Query: 36 RNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLS----KSTRDHLQTMMESV 91
R+T +KN++ + L + + + L H A K K ++ K + Q E+
Sbjct: 1777 RSTAQKNESARQQLERQNKELRSKL-HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAR 1835
Query: 92 IMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLN-MERARDKA 150
+ S+K+K++ LK+ LLQ + K+ + E ++ + ++R ++A
Sbjct: 1836 EKQAATKSLKQKDKK------LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA 1889
Query: 151 NEEGLAL------LQEEIDKMVETTELMTGNIQSLKNKIQ 184
EE + LQ E+D+ E+ E M + +LK+K++
Sbjct: 1890 EEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 32.3 bits (72), Expect = 0.45
Identities = 52/282 (18%), Positives = 121/282 (42%), Gaps = 35/282 (12%)
Query: 1 MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNL 60
+ G+ A K+ + + +++ E+ S +++ T K+N+ K L ++ +L
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 61 KHGKTAAS-----KRKTWQPLSKST--RDHLQTMMESVIMTI--LSNSIKEKEEIQYHLN 111
+ A K + + L+ S R+ LQ + I L ++E++ ++
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
Query: 112 FLKKRLLQQCETL--KVPPKKMEDLTNVSSLLNMERA----RDKANE-EG---------- 154
++ QQ E L ++ ++ N S+ +ER R K +E EG
Sbjct: 1757 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1816
Query: 155 ------LALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGV 208
+A L+E++++ + T +++ K++ + +VE+E + +Q + G
Sbjct: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 209 LSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQ 250
+ +L ++ +A ++E + N+ L ++LD S++
Sbjct: 1877 ARVKQLKRQLEEA---EEESQRINANRRKLQRELDEATESNE 1915
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 41.2 bits (95), Expect = 0.001
Identities = 59/274 (21%), Positives = 120/274 (43%), Gaps = 22/274 (8%)
Query: 8 SKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAA 67
+ K +++ K +R D + E + + K KN + + SE + + K K+
Sbjct: 1001 NNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK--KEEKSRQ 1058
Query: 68 SKRKTWQPLSKSTRDHLQTM--MESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLK 125
K + L D + + +++ I + K++EE+Q L L + Q+ LK
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1118
Query: 126 VPPKKMEDLTNVSSLLNMER-ARDKANE------EGLALLQEEIDKMVETTELMTGNIQS 178
+ ++++ L+ ER AR+KA + E L L+ E++ +++T
Sbjct: 1119 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1178
Query: 179 LKNKIQILASEVEEE----EERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPN 234
+ ++ +L ++EE E +V++M Q ++ V L E ++ +A + +
Sbjct: 1179 REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1238
Query: 235 QNA-LLKDLDILHNSSQMKSMSTFIEEAYKKLDA 267
+NA L +L +L + Q +E KKL+A
Sbjct: 1239 ENADLAGELRVLGQAKQE------VEHKKKKLEA 1266
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/215 (19%), Positives = 99/215 (46%), Gaps = 19/215 (8%)
Query: 23 KDNEEVVLSENKVRNTVK---KNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKS 79
+ EE+ E++++ T + K +N LK+L + KH+ L K ++ + +
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKEL----EQKHSQLTEEKNLLQEQLQAETELYA 911
Query: 80 TRDHLQTMMESV------IMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMED 133
+ ++ + + I+ + ++E+E+ L +K++ QQ L+ +++E+
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE---EQLEE 968
Query: 134 LTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEE 193
L +E+ +A + L++EI M + ++ + L+ +I L + + EE
Sbjct: 969 EEAARQKLQLEKVTAEAK---IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1025
Query: 194 EERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEI 228
EE+ K + ++ + + EL + K ++E+
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL 1060
Score = 33.9 bits (76), Expect = 0.15
Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 18/160 (11%)
Query: 36 RNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLS----KSTRDHLQTMMESV 91
R+T +KN++ + L + + + L H A K K ++ K + Q E+
Sbjct: 1784 RSTAQKNESARQQLERQNKELRSKL-HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAR 1842
Query: 92 IMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLN-MERARDKA 150
+ S+K+K++ LK+ LLQ + K+ + E ++ + ++R ++A
Sbjct: 1843 EKQAATKSLKQKDKK------LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA 1896
Query: 151 NEEGLAL------LQEEIDKMVETTELMTGNIQSLKNKIQ 184
EE + LQ E+D+ E+ E M + +LK+K++
Sbjct: 1897 EEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 32.3 bits (72), Expect = 0.45
Identities = 52/282 (18%), Positives = 121/282 (42%), Gaps = 35/282 (12%)
Query: 1 MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNL 60
+ G+ A K+ + + +++ E+ S +++ T K+N+ K L ++ +L
Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Query: 61 KHGKTAAS-----KRKTWQPLSKST--RDHLQTMMESVIMTI--LSNSIKEKEEIQYHLN 111
+ A K + + L+ S R+ LQ + I L ++E++ ++
Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1763
Query: 112 FLKKRLLQQCETL--KVPPKKMEDLTNVSSLLNMERA----RDKANE-EG---------- 154
++ QQ E L ++ ++ N S+ +ER R K +E EG
Sbjct: 1764 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1823
Query: 155 ------LALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGV 208
+A L+E++++ + T +++ K++ + +VE+E + +Q + G
Sbjct: 1824 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883
Query: 209 LSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQ 250
+ +L ++ +A ++E + N+ L ++LD S++
Sbjct: 1884 ARVKQLKRQLEEA---EEESQRINANRRKLQRELDEATESNE 1922
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 41.2 bits (95), Expect = 0.001
Identities = 59/274 (21%), Positives = 120/274 (43%), Gaps = 22/274 (8%)
Query: 8 SKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAA 67
+ K +++ K +R D + E + + K KN + + SE + + K K+
Sbjct: 1001 NNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK--KEEKSRQ 1058
Query: 68 SKRKTWQPLSKSTRDHLQTM--MESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLK 125
K + L D + + +++ I + K++EE+Q L L + Q+ LK
Sbjct: 1059 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1118
Query: 126 VPPKKMEDLTNVSSLLNMER-ARDKANE------EGLALLQEEIDKMVETTELMTGNIQS 178
+ ++++ L+ ER AR+KA + E L L+ E++ +++T
Sbjct: 1119 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1178
Query: 179 LKNKIQILASEVEEE----EERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPN 234
+ ++ +L ++EE E +V++M Q ++ V L E ++ +A + +
Sbjct: 1179 REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1238
Query: 235 QNA-LLKDLDILHNSSQMKSMSTFIEEAYKKLDA 267
+NA L +L +L + Q +E KKL+A
Sbjct: 1239 ENADLAGELRVLGQAKQE------VEHKKKKLEA 1266
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/215 (19%), Positives = 99/215 (46%), Gaps = 19/215 (8%)
Query: 23 KDNEEVVLSENKVRNTVK---KNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKS 79
+ EE+ E++++ T + K +N LK+L + KH+ L K ++ + +
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKEL----EQKHSQLTEEKNLLQEQLQAETELYA 911
Query: 80 TRDHLQTMMESV------IMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMED 133
+ ++ + + I+ + ++E+E+ L +K++ QQ L+ +++E+
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE---EQLEE 968
Query: 134 LTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEE 193
L +E+ +A + L++EI M + ++ + L+ +I L + + EE
Sbjct: 969 EEAARQKLQLEKVTAEAK---IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1025
Query: 194 EERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEI 228
EE+ K + ++ + + EL + K ++E+
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL 1060
Score = 33.9 bits (76), Expect = 0.15
Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 18/160 (11%)
Query: 36 RNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLS----KSTRDHLQTMMESV 91
R+T +KN++ + L + + + L H A K K ++ K + Q E+
Sbjct: 1784 RSTAQKNESARQQLERQNKELRSKL-HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAR 1842
Query: 92 IMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLN-MERARDKA 150
+ S+K+K++ LK+ LLQ + K+ + E ++ + ++R ++A
Sbjct: 1843 EKQAATKSLKQKDKK------LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA 1896
Query: 151 NEEGLAL------LQEEIDKMVETTELMTGNIQSLKNKIQ 184
EE + LQ E+D+ E+ E M + +LK+K++
Sbjct: 1897 EEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 32.3 bits (72), Expect = 0.45
Identities = 52/282 (18%), Positives = 121/282 (42%), Gaps = 35/282 (12%)
Query: 1 MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNL 60
+ G+ A K+ + + +++ E+ S +++ T K+N+ K L ++ +L
Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Query: 61 KHGKTAAS-----KRKTWQPLSKST--RDHLQTMMESVIMTI--LSNSIKEKEEIQYHLN 111
+ A K + + L+ S R+ LQ + I L ++E++ ++
Sbjct: 1704 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1763
Query: 112 FLKKRLLQQCETL--KVPPKKMEDLTNVSSLLNMERA----RDKANE-EG---------- 154
++ QQ E L ++ ++ N S+ +ER R K +E EG
Sbjct: 1764 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1823
Query: 155 ------LALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGV 208
+A L+E++++ + T +++ K++ + +VE+E + +Q + G
Sbjct: 1824 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883
Query: 209 LSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQ 250
+ +L ++ +A ++E + N+ L ++LD S++
Sbjct: 1884 ARVKQLKRQLEEA---EEESQRINANRRKLQRELDEATESNE 1922
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 41.2 bits (95), Expect = 0.001
Identities = 59/274 (21%), Positives = 120/274 (43%), Gaps = 22/274 (8%)
Query: 8 SKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAA 67
+ K +++ K +R D + E + + K KN + + SE + + K K+
Sbjct: 994 NNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK--KEEKSRQ 1051
Query: 68 SKRKTWQPLSKSTRDHLQTM--MESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLK 125
K + L D + + +++ I + K++EE+Q L L + Q+ LK
Sbjct: 1052 ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALK 1111
Query: 126 VPPKKMEDLTNVSSLLNMER-ARDKANE------EGLALLQEEIDKMVETTELMTGNIQS 178
+ ++++ L+ ER AR+KA + E L L+ E++ +++T
Sbjct: 1112 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK 1171
Query: 179 LKNKIQILASEVEEE----EERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPN 234
+ ++ +L ++EE E +V++M Q ++ V L E ++ +A + +
Sbjct: 1172 REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1231
Query: 235 QNA-LLKDLDILHNSSQMKSMSTFIEEAYKKLDA 267
+NA L +L +L + Q +E KKL+A
Sbjct: 1232 ENADLAGELRVLGQAKQE------VEHKKKKLEA 1259
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/215 (19%), Positives = 99/215 (46%), Gaps = 19/215 (8%)
Query: 23 KDNEEVVLSENKVRNTVK---KNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKS 79
+ EE+ E++++ T + K +N LK+L + KH+ L K ++ + +
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKEL----EQKHSQLTEEKNLLQEQLQAETELYA 904
Query: 80 TRDHLQTMMESV------IMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMED 133
+ ++ + + I+ + ++E+E+ L +K++ QQ L+ +++E+
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLE---EQLEE 961
Query: 134 LTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEE 193
L +E+ +A + L++EI M + ++ + L+ +I L + + EE
Sbjct: 962 EEAARQKLQLEKVTAEAK---IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
Query: 194 EERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEI 228
EE+ K + ++ + + EL + K ++E+
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL 1053
Score = 33.9 bits (76), Expect = 0.15
Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 18/160 (11%)
Query: 36 RNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLS----KSTRDHLQTMMESV 91
R+T +KN++ + L + + + L H A K K ++ K + Q E+
Sbjct: 1777 RSTAQKNESARQQLERQNKELRSKL-HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAR 1835
Query: 92 IMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLN-MERARDKA 150
+ S+K+K++ LK+ LLQ + K+ + E ++ + ++R ++A
Sbjct: 1836 EKQAATKSLKQKDKK------LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA 1889
Query: 151 NEEGLAL------LQEEIDKMVETTELMTGNIQSLKNKIQ 184
EE + LQ E+D+ E+ E M + +LK+K++
Sbjct: 1890 EEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 32.3 bits (72), Expect = 0.45
Identities = 52/282 (18%), Positives = 121/282 (42%), Gaps = 35/282 (12%)
Query: 1 MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNL 60
+ G+ A K+ + + +++ E+ S +++ T K+N+ K L ++ +L
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 61 KHGKTAAS-----KRKTWQPLSKST--RDHLQTMMESVIMTI--LSNSIKEKEEIQYHLN 111
+ A K + + L+ S R+ LQ + I L ++E++ ++
Sbjct: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
Query: 112 FLKKRLLQQCETL--KVPPKKMEDLTNVSSLLNMERA----RDKANE-EG---------- 154
++ QQ E L ++ ++ N S+ +ER R K +E EG
Sbjct: 1757 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1816
Query: 155 ------LALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGV 208
+A L+E++++ + T +++ K++ + +VE+E + +Q + G
Sbjct: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 209 LSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQ 250
+ +L ++ +A ++E + N+ L ++LD S++
Sbjct: 1877 ARVKQLKRQLEEA---EEESQRINANRRKLQRELDEATESNE 1915
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.122 0.313
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,720,791
Number of Sequences: 37866
Number of extensions: 351141
Number of successful extensions: 3080
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 398
Number of HSP's that attempted gapping in prelim test: 2401
Number of HSP's gapped (non-prelim): 999
length of query: 268
length of database: 18,247,518
effective HSP length: 100
effective length of query: 168
effective length of database: 14,460,918
effective search space: 2429434224
effective search space used: 2429434224
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.