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Search of human proteins with 38679957
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
(859 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38679957 active breakpoint cluster region-related protein is... 1715 0.0
gi|229094128 active breakpoint cluster region-related protein i... 1617 0.0
gi|38679954 active breakpoint cluster region-related protein is... 1543 0.0
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 1136 0.0
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 1045 0.0
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 137 3e-32
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 137 3e-32
gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo sa... 135 2e-31
gi|188497642 ARHGAP15 [Homo sapiens] 129 1e-29
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 126 8e-29
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 126 8e-29
gi|239746665 PREDICTED: hypothetical protein XP_002343826 [Homo ... 120 5e-27
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 120 5e-27
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 119 2e-26
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] 117 6e-26
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap... 116 8e-26
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 116 8e-26
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 115 2e-25
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 115 2e-25
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 115 2e-25
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 113 9e-25
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 113 9e-25
gi|239757684 PREDICTED: hypothetical protein [Homo sapiens] 112 1e-24
gi|239752174 PREDICTED: hypothetical protein XP_002348160 [Homo ... 112 1e-24
gi|239746697 PREDICTED: hypothetical protein XP_002343833 [Homo ... 112 1e-24
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 112 2e-24
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 111 3e-24
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 111 3e-24
gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Hom... 109 1e-23
gi|23510413 sorting nexin 26 [Homo sapiens] 109 1e-23
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 1715 bits (4441), Expect = 0.0
Identities = 859/859 (100%), Positives = 859/859 (100%)
Query: 1 MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQL 60
MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQL
Sbjct: 1 MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQL 60
Query: 61 SARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPL 120
SARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPL
Sbjct: 61 SARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPL 120
Query: 121 KATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ 180
KATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ
Sbjct: 121 KATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ 180
Query: 181 LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPI 240
LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPI
Sbjct: 181 LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPI 240
Query: 241 DRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETR 300
DRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETR
Sbjct: 241 DRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETR 300
Query: 301 QLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSP 360
QLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSP
Sbjct: 301 QLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSP 360
Query: 361 EESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLL 420
EESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLL
Sbjct: 361 EESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLL 420
Query: 421 NSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCF 480
NSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCF
Sbjct: 421 NSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCF 480
Query: 481 KLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKT 540
KLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKT
Sbjct: 481 KLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKT 540
Query: 541 RVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDP 600
RVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDP
Sbjct: 541 RVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDP 600
Query: 601 QTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKV 660
QTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKV
Sbjct: 601 QTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKV 660
Query: 661 PYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGT 720
PYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGT
Sbjct: 661 PYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGT 720
Query: 721 LKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLK 780
LKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLK
Sbjct: 721 LKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLK 780
Query: 781 RVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 840
RVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH
Sbjct: 781 RVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 840
Query: 841 PPISFAELKRNTLYFSTDV 859
PPISFAELKRNTLYFSTDV
Sbjct: 841 PPISFAELKRNTLYFSTDV 859
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 1617 bits (4186), Expect = 0.0
Identities = 813/813 (100%), Positives = 813/813 (100%)
Query: 47 MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY 106
MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY
Sbjct: 1 MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY 60
Query: 107 INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS 166
INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS
Sbjct: 61 INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS 120
Query: 167 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS 226
QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS
Sbjct: 121 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS 180
Query: 227 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID 286
HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID
Sbjct: 181 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID 240
Query: 287 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC 346
PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC
Sbjct: 241 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC 300
Query: 347 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER 406
KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER
Sbjct: 301 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER 360
Query: 407 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV 466
LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV
Sbjct: 361 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV 420
Query: 467 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL 526
LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL
Sbjct: 421 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL 480
Query: 527 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI 586
EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI
Sbjct: 481 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI 540
Query: 587 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG 646
VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG
Sbjct: 541 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG 600
Query: 647 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL 706
VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL
Sbjct: 601 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL 660
Query: 707 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD 766
LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD
Sbjct: 661 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD 720
Query: 767 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD 826
PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD
Sbjct: 721 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD 780
Query: 827 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 859
VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV
Sbjct: 781 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 1543 bits (3996), Expect = 0.0
Identities = 781/793 (98%), Positives = 783/793 (98%), Gaps = 5/793 (0%)
Query: 72 SPTPPEGLAP-----GVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATT 126
+PT P +P VEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATT
Sbjct: 30 TPTSPGSGSPFLVAVKVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATT 89
Query: 127 SQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKA 186
SQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKA
Sbjct: 90 SQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKA 149
Query: 187 FVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRS 246
FVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRS
Sbjct: 150 FVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRS 209
Query: 247 TLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDG 306
TLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDG
Sbjct: 210 TLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDG 269
Query: 307 FLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEAS 366
FLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEAS
Sbjct: 270 FLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEAS 329
Query: 367 PQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIP 426
PQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIP
Sbjct: 330 PQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIP 389
Query: 427 FRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVH 486
FRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVH
Sbjct: 390 FRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVH 449
Query: 487 NIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDT 546
NIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDT
Sbjct: 450 NIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDT 509
Query: 547 AEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETK 606
AEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETK
Sbjct: 510 AEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETK 569
Query: 607 NWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQ 666
NWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQ
Sbjct: 570 NWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQ 629
Query: 667 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR 726
CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR
Sbjct: 630 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR 689
Query: 727 ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE 786
ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE
Sbjct: 690 ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE 749
Query: 787 PINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 846
PINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA
Sbjct: 750 PINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 809
Query: 847 ELKRNTLYFSTDV 859
ELKRNTLYFSTDV
Sbjct: 810 ELKRNTLYFSTDV 822
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 1136 bits (2939), Expect = 0.0
Identities = 573/832 (68%), Positives = 685/832 (82%), Gaps = 11/832 (1%)
Query: 35 EEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDG-VSPTPPEGLAPGVEAGKGLEMRK 93
EEQ+ +G +PYID+SP+ SP LS++ +G D VS A ++ KGLEMRK
Sbjct: 444 EEQRRHQDG---LPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRK 500
Query: 94 LVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEF 153
VLSG LASEE Y++ LEALLLPMKPLKA ATTSQPVLT QQIETIF+K+ ++YEIHKEF
Sbjct: 501 WVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEF 560
Query: 154 YDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISE 213
YD L P+VQQW Q +G LFQKLASQLGVY+AFVDNY VA+E AEKC Q+N QF +ISE
Sbjct: 561 YDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISE 620
Query: 214 ELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRI 273
L+ + KD+KD T ++E LLYKP+DRVTRSTLVLHDLLKHTP HPD+PLLQDALRI
Sbjct: 621 NLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRI 680
Query: 274 SQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKL 333
SQNFLSSINE+I PRR ++T KGE RQL+KD F+VE+ E +RKLRHVFLFTD+LLC KL
Sbjct: 681 SQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKL 740
Query: 334 KKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQK 393
KK S GK QQYDCKWYIPL DL F +E EA P + PD EL+ +K+KIS +K++IQ+
Sbjct: 741 KKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQR 800
Query: 394 EK-ANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWRE 452
EK ANKG S+A ERLKKK+ E E LLLL SP++ FR+H+RNGKSY FL+SSDYER+EWRE
Sbjct: 801 EKRANKG-SKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRE 859
Query: 453 AIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHS 512
I++ QKK ++F L+SVELQ+LT SC KL+TVH+IP+T NK+DDESPGLYGFL+VIVHS
Sbjct: 860 NIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHS 919
Query: 513 AKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEK 572
A GFKQS+NLYCTLEVDSFGYFV+KAKTRV+RDTAEP W+EEFEIELEGSQ+LRILCYEK
Sbjct: 920 ATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEK 979
Query: 573 CYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMS 632
CY+KTK+ K++ E D++MGKGQ+QLDPQ ++ ++W VI MNGI+V+ S+KF SR+ S
Sbjct: 980 CYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFS 1039
Query: 633 LKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQ 692
LKR PS+KQTGVFGVKI+VVTKRERSKVPYIVRQCVEE+E+RG+EEVGIYR+SGVATDIQ
Sbjct: 1040 LKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQ 1099
Query: 693 ALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAA 752
ALKA FD NNKD+ +M+S+MD+NAIAGTLKLYFRELPEPL TD YP F EGIALSDP A
Sbjct: 1100 ALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVA 1159
Query: 753 KENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVES 812
KE+CM++LL SLP+ NL+TFLFLL+HLKRVAEKE +NKMSLHNLATVFGPTLLRPSE ES
Sbjct: 1160 KESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKES 1219
Query: 813 K-----AHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 859
K + + D WS +VM+QVQVLLY+LQ I + KR ++ FST+V
Sbjct: 1220 KLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV 1271
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 1045 bits (2702), Expect = 0.0
Identities = 541/832 (65%), Positives = 645/832 (77%), Gaps = 55/832 (6%)
Query: 35 EEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDG-VSPTPPEGLAPGVEAGKGLEMRK 93
EEQ+ +G +PYID+SP+ SP LS++ +G D VS A ++ KGLEMRK
Sbjct: 444 EEQRRHQDG---LPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRK 500
Query: 94 LVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEF 153
VLSG LASEE Y++ LEALLLPMKPLKA ATTSQPVLT QQIETIF+K+ ++YEIHKEF
Sbjct: 501 WVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEF 560
Query: 154 YDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISE 213
YD L P+VQQW Q +G LFQKLASQLGVY+AFVDNY VA+E AEKC Q+N QF +ISE
Sbjct: 561 YDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISE 620
Query: 214 ELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRI 273
L+ + KD+KD T ++E LLYKP+DRVTRSTLVLHDLLKHTP HPD+PLLQDALRI
Sbjct: 621 NLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRI 680
Query: 274 SQNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKL 333
SQNFLSSINE+I PRR ++T KGE RQL+KD F+VE+ E +RKLRHVFLFTD+LLC KL
Sbjct: 681 SQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKL 740
Query: 334 KKTSAGKHQQYDCKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQK 393
KK S GK QQYDCKWYIPL DL F +E EA P + PD EL+ +K+KIS +K++IQ+
Sbjct: 741 KKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQR 800
Query: 394 EK-ANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWRE 452
EK ANKG S+A ERLKKK+ E E LLLL SP++ FR+H+RNGKSY FL+SSDYER+EWRE
Sbjct: 801 EKRANKG-SKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRE 859
Query: 453 AIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHS 512
I++ QKK ++F L+SVELQ+LT SC KL+TVH+IP+T NK+DDESPGLYGFL+VIVHS
Sbjct: 860 NIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHS 919
Query: 513 AKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEK 572
A GFKQS+NLYCTLEVDSFGYFV+KAKTRV+RDTAEP W+E
Sbjct: 920 ATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNE------------------- 960
Query: 573 CYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMS 632
LDPQ ++ ++W VI MNGI+V+ S+KF SR+ S
Sbjct: 961 -------------------------LDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFS 995
Query: 633 LKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQ 692
LKR PS+KQTGVFGVKI+VVTKRERSKVPYIVRQCVEE+E+RG+EEVGIYR+SGVATDIQ
Sbjct: 996 LKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQ 1055
Query: 693 ALKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAA 752
ALKA FD NNKD+ +M+S+MD+NAIAGTLKLYFRELPEPL TD YP F EGIALSDP A
Sbjct: 1056 ALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVA 1115
Query: 753 KENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVES 812
KE+CM++LL SLP+ NL+TFLFLL+HLKRVAEKE +NKMSLHNLATVFGPTLLRPSE ES
Sbjct: 1116 KESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKES 1175
Query: 813 K-----AHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 859
K + + D WS +VM+QVQVLLY+LQ I + KR ++ FST+V
Sbjct: 1176 KLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV 1227
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 137 bits (346), Expect = 3e-32
Identities = 83/198 (41%), Positives = 114/198 (57%), Gaps = 8/198 (4%)
Query: 625 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 682
KF R +L+ K + VFG ++ + +RERS+VP V+QC+ VE RG++ G+Y
Sbjct: 305 KFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLY 364
Query: 683 RISGVATDIQALKAVFDANNKDILLMLSD---MDINAIAGTLKLYFRELPEPLLTDRLYP 739
RISG IQ L+ D + + L L D D++ I G LKL+FRELPEPL +
Sbjct: 365 RISGNLATIQKLRYKVDHDER---LDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFR 421
Query: 740 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 799
F+ I L D A + C+ L+RSLP PN T L +HL RV E N+MS+ ++A V
Sbjct: 422 QFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIV 481
Query: 800 FGPTLLRPSEVESKAHLT 817
FGPTLLRP E+ +T
Sbjct: 482 FGPTLLRPEVEETSMPMT 499
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 137 bits (346), Expect = 3e-32
Identities = 83/198 (41%), Positives = 114/198 (57%), Gaps = 8/198 (4%)
Query: 625 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 682
KF R +L+ K + VFG ++ + +RERS+VP V+QC+ VE RG++ G+Y
Sbjct: 332 KFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLY 391
Query: 683 RISGVATDIQALKAVFDANNKDILLMLSD---MDINAIAGTLKLYFRELPEPLLTDRLYP 739
RISG IQ L+ D + + L L D D++ I G LKL+FRELPEPL +
Sbjct: 392 RISGNLATIQKLRYKVDHDER---LDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFR 448
Query: 740 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 799
F+ I L D A + C+ L+RSLP PN T L +HL RV E N+MS+ ++A V
Sbjct: 449 QFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIV 508
Query: 800 FGPTLLRPSEVESKAHLT 817
FGPTLLRP E+ +T
Sbjct: 509 FGPTLLRPEVEETSMPMT 526
>gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo
sapiens]
Length = 1194
Score = 135 bits (340), Expect = 2e-31
Identities = 111/372 (29%), Positives = 177/372 (47%), Gaps = 36/372 (9%)
Query: 504 GFLHVIVHSAKGFK----QSANLYCTLEVDSFGYFVSKAKTRVFR-DTAEPKWDEEFEIE 558
G + V + A+ K S +++C ++VDS V+KA+T + T D F IE
Sbjct: 680 GLMSVHFYGAEDLKPPRIDSKDVFCAIQVDS----VNKARTALLTCRTTFLDMDHTFNIE 735
Query: 559 LEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDV-IEMNG 617
+E +Q L+++ + ++ T +++ G + L TK V +E G
Sbjct: 736 IENAQHLKLVVFS--WEPTPRK-------NRVCCHGTVVLPTLFRVTKTHQLAVKLEPRG 786
Query: 618 IKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERS--KVPYIVRQCVEEVEKRG 675
+ + SL ++ +FGV I V ++E VP ++++C+ E+EKRG
Sbjct: 787 LIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRG 846
Query: 676 IEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLT 734
+ VG+YR+ G A + L+ F+ ++K + L + DIN I G LK Y RELP PL+T
Sbjct: 847 CQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLIT 906
Query: 735 DRLYPAFMEGIALSDPAAKEN----------CMMHLLRSLPDPNLITFLFLLEHLKRVAE 784
+LY A ++ +A S N + LL LP+ T LL+HLK VA
Sbjct: 907 KQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVAS 966
Query: 785 KEPINKMSLHNLATVFGPTLL----RPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 840
+NKM+ NLA FGP LL PS ++ S + D ++VL Y LQ
Sbjct: 967 YHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLLQL 1026
Query: 841 PPISFAELKRNT 852
P+ +K++T
Sbjct: 1027 WPVQRLTVKKST 1038
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 129 bits (324), Expect = 1e-29
Identities = 79/202 (39%), Positives = 109/202 (53%), Gaps = 9/202 (4%)
Query: 610 TDVIEMNGIKVEFSMKFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQC 667
+D + N +K KF +R SLK K + +FG + V +RE S VP+ V+QC
Sbjct: 243 SDTSDKNRVKSRLK-KFITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQC 301
Query: 668 VEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM---DINAIAGTLKLY 724
+E VEKRG++ GIYR+SG IQ L+ + + K L L D DI+ + G LK++
Sbjct: 302 IEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEK---LNLDDSQWEDIHVVTGALKMF 358
Query: 725 FRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAE 784
FRELPEPL + F+E I D + + L++ LP PN T L HL ++
Sbjct: 359 FRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVA 418
Query: 785 KEPINKMSLHNLATVFGPTLLR 806
K N MS +L VFGPTLLR
Sbjct: 419 KASKNLMSTQSLGIVFGPTLLR 440
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 126 bits (317), Expect = 8e-29
Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%)
Query: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 703
V+ ++ + K +K P +V C+ E+E RG+ G+YR+SG + I+ +K FD + +
Sbjct: 265 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 324
Query: 704 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 761
DI + + + DIN I G LKLYFR+LP PL+T YP F+E + DP + + L
Sbjct: 325 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
Query: 762 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 816
+ LP + T +L+ HLKRV E N M+ NL VFGPTL+R E+++ A L
Sbjct: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 438
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 126 bits (317), Expect = 8e-29
Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%)
Query: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 703
V+ ++ + K +K P +V C+ E+E RG+ G+YR+SG + I+ +K FD + +
Sbjct: 239 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 298
Query: 704 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 761
DI + + + DIN I G LKLYFR+LP PL+T YP F+E + DP + + L
Sbjct: 299 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
Query: 762 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 816
+ LP + T +L+ HLKRV E N M+ NL VFGPTL+R E+++ A L
Sbjct: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 412
>gi|239746665 PREDICTED: hypothetical protein XP_002343826 [Homo
sapiens]
Length = 181
Score = 120 bits (301), Expect = 5e-27
Identities = 63/105 (60%), Positives = 80/105 (76%), Gaps = 10/105 (9%)
Query: 734 TDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSL 793
+D L PA ALSDP AK++CM++LL SLP+ NL+TFLFLL+HL+R+AEKE +NKMSL
Sbjct: 32 SDPLPPA-----ALSDPVAKKSCMLNLLSSLPEANLLTFLFLLDHLERMAEKEAVNKMSL 86
Query: 794 HNLATVFGPTLLRPSEVESK-----AHLTSAADIWSHDVMAQVQV 833
HNL TVFGPTLLRPSE ESK + + D WS +VM+Q+Q+
Sbjct: 87 HNLGTVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQIQI 131
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 120 bits (301), Expect = 5e-27
Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 9/190 (4%)
Query: 625 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 682
KF +R +L+ K + VFG ++ + +RE VP V+ C+E VE+ G++ GIY
Sbjct: 632 KFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIY 691
Query: 683 RISGVATDIQALKAVFDANNKDILLMLSDM---DINAIAGTLKLYFRELPEPLLTDRLYP 739
R+SG IQ L+ A N D L L+D DI+ I G LK++FRELPEPL T +
Sbjct: 692 RVSGNLAVIQKLRF---AVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFN 748
Query: 740 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 799
F+ I +P + + L+R LP PN T L HL+RV E N+M+ ++A V
Sbjct: 749 DFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIV 807
Query: 800 FGPTLLRPSE 809
FGPTLL+P +
Sbjct: 808 FGPTLLKPEK 817
>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
sapiens]
Length = 735
Score = 119 bits (297), Expect = 2e-26
Identities = 107/368 (29%), Positives = 169/368 (45%), Gaps = 57/368 (15%)
Query: 502 LYGFLHVIVHSAKGFKQSA-----NLYCTLEVDSFGYFVSKAKTRVFRDTAE-PKWDEEF 555
L+G L + ++ G + + +L C L+VD ++A+T R + + D F
Sbjct: 264 LWGRLSLHLYGLGGLRPAPGATPRDLCCLLQVDG----EARARTGPLRGGPDFLRLDHTF 319
Query: 556 EIELEGSQSLR--ILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQ-----LDPQTVETKNW 608
+ELE ++ LR +L ++ + + ++ + Q Q L+PQ +
Sbjct: 320 HLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTVFRGCQAQQLAVRLEPQGL----- 374
Query: 609 HTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRER--SKVPYIVRQ 666
K T + + P+ + VFG+ + ++ +RER +VP I+++
Sbjct: 375 -------------LYAKLTLSEQ--QEAPATAEPRVFGLPLPLLVERERPPGQVPLIIQK 419
Query: 667 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM--DINAIAGTLKLY 724
CV ++E+RG+ VG+YR+ G A + L+ F+ ++ + L D+ DIN I G LK Y
Sbjct: 420 CVGQIERRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVCLS-EDLYPDINVITGILKDY 478
Query: 725 FRELPEPLLTDRLYPAFMEGIALSDP---AAKENCMMHLLRSLPDPNLITFLFLLEHLKR 781
RELP PL+T LY +E +A P LL LPD T LL+HL+
Sbjct: 479 LRELPTPLITQPLYKVVLEAMARDPPNRVPPTTEGTRGLLSCLPDVERATLTLLLDHLRL 538
Query: 782 VAEKEPINKMSLHNLATVFGPTLL-------RPSEVESKAHLTSAADIWSHDVMAQVQVL 834
V+ N+M+ NLA FGP LL RP S L SA D H ++VL
Sbjct: 539 VSSFHAYNRMTPQNLAVCFGPVLLPARQAPTRPRARSSGPGLASAVDFKHH-----IEVL 593
Query: 835 LYYLQHPP 842
Y LQ P
Sbjct: 594 HYLLQSWP 601
>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
Length = 1136
Score = 117 bits (292), Expect = 6e-26
Identities = 76/217 (35%), Positives = 112/217 (51%), Gaps = 27/217 (12%)
Query: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 703
+FG S + VP+IV++CV E+E+R + GIYR++GV T ++ L F+ N K
Sbjct: 758 LFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFE-NGK 816
Query: 704 DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENC------- 756
+ L+ LS + I+ LKLY R+LPEPL++ RLY + G+A A+
Sbjct: 817 E-LVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELV-GLAKDSLKAEAEAKAASRGR 874
Query: 757 ----------------MMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVF 800
+ LLR LP N + +LL HL+R+ E E NKM+ NL VF
Sbjct: 875 QDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVF 934
Query: 801 GPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYY 837
GPTLLRP E+ L+S D + H ++++Y
Sbjct: 935 GPTLLRPRPTEATVSLSSLVD-YPHQARVIETLIVHY 970
>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
sapiens]
Length = 890
Score = 116 bits (291), Expect = 8e-26
Identities = 74/214 (34%), Positives = 117/214 (54%), Gaps = 7/214 (3%)
Query: 628 SRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGV 687
SR K+ +K++ VFG + + +VP +++ C E VE+ G+ + GIYR+SGV
Sbjct: 3 SRQKGKKKGSAKER--VFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGV 59
Query: 688 ATDIQALKAVFDANNK-DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIA 746
+++IQ L+ F++ K D+ + DI+ ++ K YFRELP+PLLT RLY F E +
Sbjct: 60 SSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVG 119
Query: 747 LSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLR 806
+ + ++ +LR LP PN T FL+ HL +A M NLA V+ P LLR
Sbjct: 120 VQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLR 179
Query: 807 PSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 840
++E+ +AA + +V Q V+ + L H
Sbjct: 180 SKDIEASGFNGTAAFM---EVRVQSIVVEFILTH 210
>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
sapiens]
Length = 1101
Score = 116 bits (291), Expect = 8e-26
Identities = 74/214 (34%), Positives = 117/214 (54%), Gaps = 7/214 (3%)
Query: 628 SRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGV 687
SR K+ +K++ VFG + + +VP +++ C E VE+ G+ + GIYR+SGV
Sbjct: 3 SRQKGKKKGSAKER--VFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGV 59
Query: 688 ATDIQALKAVFDANNK-DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIA 746
+++IQ L+ F++ K D+ + DI+ ++ K YFRELP+PLLT RLY F E +
Sbjct: 60 SSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVG 119
Query: 747 LSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLR 806
+ + ++ +LR LP PN T FL+ HL +A M NLA V+ P LLR
Sbjct: 120 VQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLR 179
Query: 807 PSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 840
++E+ +AA + +V Q V+ + L H
Sbjct: 180 SKDIEASGFNGTAAFM---EVRVQSIVVEFILTH 210
>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
sapiens]
Length = 731
Score = 115 bits (288), Expect = 2e-25
Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 18/187 (9%)
Query: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 700
VFG ++ + +RE VP +R C+ V+KRG++ GIYR+SG +Q L+ + D A
Sbjct: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579
Query: 701 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGI 745
D + + DI+ + G LKL+ RELP+PL+ L P F +
Sbjct: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639
Query: 746 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 805
ALS+ + + L+ S+P PN T +LLEHL RV N+M+ HNL VFGPTL
Sbjct: 640 ALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 699
Query: 806 RPSEVES 812
RP + S
Sbjct: 700 RPEQETS 706
>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
sapiens]
Length = 547
Score = 115 bits (288), Expect = 2e-25
Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 18/187 (9%)
Query: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 700
VFG ++ + +RE VP +R C+ V+KRG++ GIYR+SG +Q L+ + D A
Sbjct: 336 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 395
Query: 701 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGI 745
D + + DI+ + G LKL+ RELP+PL+ L P F +
Sbjct: 396 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 455
Query: 746 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 805
ALS+ + + L+ S+P PN T +LLEHL RV N+M+ HNL VFGPTL
Sbjct: 456 ALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 515
Query: 806 RPSEVES 812
RP + S
Sbjct: 516 RPEQETS 522
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 115 bits (287), Expect = 2e-25
Identities = 77/219 (35%), Positives = 111/219 (50%), Gaps = 12/219 (5%)
Query: 633 LKRTPSKKQT--GVFGVKISVVTKRERSK-VPYIVRQCVEEVEKRGIEEVGIYRISGVAT 689
+++T KK T G FGV++ ++ +P IV C + VE+RG+E GIYR+ G
Sbjct: 1131 MRKTFEKKPTATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNA 1190
Query: 690 DIQALKAVFDANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALS 748
I +++ + DI + D+N I+ LK +FR+LPEPL T+ Y F+E
Sbjct: 1191 AISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKE 1250
Query: 749 DPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPS 808
DP + + L+ LP+ + T FL HLK VAE NKM NLA VFGPTL+R S
Sbjct: 1251 DPLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTS 1310
Query: 809 EVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAE 847
E +T D Q +++ +QH F E
Sbjct: 1311 EDNMTHMVTHMPD--------QYKIVETLIQHHDWFFTE 1341
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 113 bits (282), Expect = 9e-25
Identities = 64/196 (32%), Positives = 107/196 (54%), Gaps = 4/196 (2%)
Query: 639 KKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVF 698
K+ V+ ++ + K ++ P +V C+ E+E RG++ G+YR+SG I+ +K F
Sbjct: 269 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF 328
Query: 699 DANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCM 757
D + + + + DIN I G LKLYFR+LP P++T Y F++ +S+ + +
Sbjct: 329 DRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAV 388
Query: 758 MHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLT 817
+L LP + T +L+ HLK+V E N M+ NL VFGPTL+RP E + LT
Sbjct: 389 HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE---DSTLT 445
Query: 818 SAADIWSHDVMAQVQV 833
+ D+ ++ Q+ +
Sbjct: 446 TLHDMRYQKLIVQILI 461
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 113 bits (282), Expect = 9e-25
Identities = 64/196 (32%), Positives = 107/196 (54%), Gaps = 4/196 (2%)
Query: 639 KKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVF 698
K+ V+ ++ + K ++ P +V C+ E+E RG++ G+YR+SG I+ +K F
Sbjct: 133 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF 192
Query: 699 DANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCM 757
D + + + + DIN I G LKLYFR+LP P++T Y F++ +S+ + +
Sbjct: 193 DRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAV 252
Query: 758 MHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLT 817
+L LP + T +L+ HLK+V E N M+ NL VFGPTL+RP E + LT
Sbjct: 253 HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE---DSTLT 309
Query: 818 SAADIWSHDVMAQVQV 833
+ D+ ++ Q+ +
Sbjct: 310 TLHDMRYQKLIVQILI 325
>gi|239757684 PREDICTED: hypothetical protein [Homo sapiens]
Length = 181
Score = 112 bits (281), Expect = 1e-24
Identities = 58/93 (62%), Positives = 74/93 (79%), Gaps = 5/93 (5%)
Query: 746 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 805
ALSDP A+++CM++LL SLP+ NL+TFLFLL+ L+RVAEKE +NKMSLHNLATVFGPTLL
Sbjct: 39 ALSDPVARKSCMLNLLLSLPEANLLTFLFLLDRLERVAEKEAVNKMSLHNLATVFGPTLL 98
Query: 806 RPSEVESK-----AHLTSAADIWSHDVMAQVQV 833
RPSE ESK + + D S +VM+Q+Q+
Sbjct: 99 RPSEKESKLPANPSQPITMTDSRSLEVMSQIQI 131
>gi|239752174 PREDICTED: hypothetical protein XP_002348160 [Homo
sapiens]
Length = 181
Score = 112 bits (281), Expect = 1e-24
Identities = 58/93 (62%), Positives = 74/93 (79%), Gaps = 5/93 (5%)
Query: 746 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 805
ALSDP A+++CM++LL SLP+ NL+TFLFLL+ L+RVAEKE +NKMSLHNLATVFGPTLL
Sbjct: 39 ALSDPVARKSCMLNLLLSLPEANLLTFLFLLDRLERVAEKEAVNKMSLHNLATVFGPTLL 98
Query: 806 RPSEVESK-----AHLTSAADIWSHDVMAQVQV 833
RPSE ESK + + D S +VM+Q+Q+
Sbjct: 99 RPSEKESKLPANPSQPITMTDSRSLEVMSQIQI 131
>gi|239746697 PREDICTED: hypothetical protein XP_002343833 [Homo
sapiens]
Length = 181
Score = 112 bits (281), Expect = 1e-24
Identities = 58/93 (62%), Positives = 74/93 (79%), Gaps = 5/93 (5%)
Query: 746 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 805
ALSDP A+++CM++LL SLP+ NL+TFLFLL+ L+RVAEKE +NKMSLHNLATVFGPTLL
Sbjct: 39 ALSDPVARKSCMLNLLLSLPEANLLTFLFLLDRLERVAEKEAVNKMSLHNLATVFGPTLL 98
Query: 806 RPSEVESK-----AHLTSAADIWSHDVMAQVQV 833
RPSE ESK + + D S +VM+Q+Q+
Sbjct: 99 RPSEKESKLPANPSQPITMTDSRSLEVMSQIQI 131
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 112 bits (279), Expect = 2e-24
Identities = 67/167 (40%), Positives = 89/167 (53%), Gaps = 2/167 (1%)
Query: 645 FGVKISVVTKR-ERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 703
FGV++ E +VP IV C VE RG+E GIYR+ G + +L+ +
Sbjct: 809 FGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPG 868
Query: 704 DILLMLSD-MDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLR 762
DI L D+N I+ LK +FR+LPEPL TD Y F+E + D + + L+R
Sbjct: 869 DINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIR 928
Query: 763 SLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSE 809
LP T FL+ HLK +A+ NKM NLA VFGPTL+R SE
Sbjct: 929 DLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSE 975
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 111 bits (278), Expect = 3e-24
Identities = 83/256 (32%), Positives = 132/256 (51%), Gaps = 20/256 (7%)
Query: 600 PQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSK---KQTG-----VFGVKISV 651
PQ+V T + V + +G + F F +K P+K KQ G VFG +
Sbjct: 324 PQSV-TNSVPKPVSKKHGKLITFLRTF------MKSRPTKQKLKQRGILKERVFGCDLGE 376
Query: 652 VTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANN-KDILLMLS 710
+VP +++ C +E+ GI + GIYR+SGVA++IQ L+ FD+ + D+
Sbjct: 377 HLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFDSEHVPDLTKEPY 435
Query: 711 DMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLI 770
DI+++ KLYFRELP PLLT +LY F + ++ + + + +++ LP P+
Sbjct: 436 VQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYR 495
Query: 771 TFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQ 830
T FL+ HL +A+ I M NLA V+ P LLR ++ES +AA + +V Q
Sbjct: 496 TLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFM---EVRIQ 552
Query: 831 VQVLLYYLQHPPISFA 846
V+ + L H + F+
Sbjct: 553 SVVVEFILNHVDVLFS 568
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 111 bits (277), Expect = 3e-24
Identities = 75/223 (33%), Positives = 119/223 (53%), Gaps = 13/223 (5%)
Query: 633 LKRTPSK---KQTG-----VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRI 684
+K P+K KQ G VFG + +VP +++ C +E+ GI + GIYR+
Sbjct: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRL 59
Query: 685 SGVATDIQALKAVFDANN-KDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFME 743
SGVA++IQ L+ FD+ + D+ DI+++ KLYFRELP PLLT +LY F +
Sbjct: 60 SGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSD 119
Query: 744 GIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPT 803
++ + + + +++ LP P+ T FL+ HL +A+ I M NLA V+ P
Sbjct: 120 AVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPN 179
Query: 804 LLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 846
LLR ++ES +AA + +V Q V+ + L H + F+
Sbjct: 180 LLRSKQIESACFSGTAAFM---EVRIQSVVVEFILNHVDVLFS 219
>gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Homo
sapiens]
Length = 2063
Score = 109 bits (273), Expect = 1e-23
Identities = 84/327 (25%), Positives = 146/327 (44%), Gaps = 58/327 (17%)
Query: 75 PPEGLAPGVEAGKG--------LEMRKLVLSGFLASEEIYINQLEALLLP-MKPLKA--T 123
PPE P E ++MRK V L +E+ Y+ L L+ M+PLK
Sbjct: 1042 PPEAARPADEPTPASKCCSKPQVDMRKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPEN 1101
Query: 124 ATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ--- 180
+ P L ++ IF +I ++ E H++F + + +Q W +Q +G L + S+
Sbjct: 1102 SVLCDPSL----VDEIFDQIPELLEHHEQFLEQVRHCMQTWHAQQKVGALLVQSFSKDVL 1157
Query: 181 LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPI 240
+ +Y A++DN+ A + ++ F K E+ +++ + L+ KP+
Sbjct: 1158 VNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQ-------SMRENKEKQALSDLMIKPV 1210
Query: 241 DRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSIN----------------ED 284
R+ R L++ DLLKHTP DHPD+PLL +A R + IN ++
Sbjct: 1211 QRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQE 1270
Query: 285 IDPRRTAVTTPKGETRQLVKDGFLVEVSE-SSRKLRHVFLFTDVLLCAKLKKTSAGKHQ- 342
I+ + + R+ ++ ++EV +K R +FLFTD+++C LK+ S +
Sbjct: 1271 IEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRS 1330
Query: 343 ---------------QYDCKWYIPLAD 354
+Y W +PL D
Sbjct: 1331 SMSLYTAASVIDTASKYKMLWKLPLED 1357
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 109 bits (273), Expect = 1e-23
Identities = 75/207 (36%), Positives = 112/207 (54%), Gaps = 9/207 (4%)
Query: 644 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 703
VFG + VP ++R C E +E G+ + GIYR+SGV+++IQ L+ FD+
Sbjct: 312 VFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVD-GIYRLSGVSSNIQRLRHEFDSERI 370
Query: 704 DILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMM--HL 760
L + + DI++++ KLYFRELP PLLT +LY F E A+S P +E + +
Sbjct: 371 PELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSE--AMSVPGEEERLVRVHDV 428
Query: 761 LRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAA 820
++ LP P+ T +LL HL R+A M NLA V+ P LLR E+ES +AA
Sbjct: 429 IQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAA 488
Query: 821 DIWSHDVMAQVQVLLYYLQHPPISFAE 847
+V Q V+ + L H + F++
Sbjct: 489 ---FREVRVQSVVVEFLLTHVDVLFSD 512
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,549,689
Number of Sequences: 37866
Number of extensions: 1514585
Number of successful extensions: 6026
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 147
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 5572
Number of HSP's gapped (non-prelim): 345
length of query: 859
length of database: 18,247,518
effective HSP length: 111
effective length of query: 748
effective length of database: 14,044,392
effective search space: 10505205216
effective search space used: 10505205216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.