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Search of human proteins with 38524616
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
(646 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 1303 0.0
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 819 0.0
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 410 e-114
gi|62865631 solute carrier family 27 (fatty acid transporter), m... 410 e-114
gi|13325055 solute carrier family 27 (fatty acid transporter), m... 410 e-114
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 396 e-110
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 376 e-104
gi|227499621 solute carrier family 27 (fatty acid transporter), ... 324 1e-88
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 105 1e-22
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 105 1e-22
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 99 9e-21
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 92 2e-18
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 92 2e-18
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 92 2e-18
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 89 1e-17
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 88 2e-17
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 82 1e-15
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 78 3e-14
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 75 2e-13
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 71 3e-12
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 71 3e-12
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 67 5e-11
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 66 1e-10
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 51 3e-06
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 44 4e-04
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 41 0.004
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 41 0.004
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 41 0.004
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor... 36 0.096
gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo... 36 0.096
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 1303 bits (3372), Expect = 0.0
Identities = 646/646 (100%), Positives = 646/646 (100%)
Query: 1 MRAPGAGAASVVSLALLWLLGLPWTWSAAAALGVYVGSGGWRFLRIVCKTARRDLFGLSV 60
MRAPGAGAASVVSLALLWLLGLPWTWSAAAALGVYVGSGGWRFLRIVCKTARRDLFGLSV
Sbjct: 1 MRAPGAGAASVVSLALLWLLGLPWTWSAAAALGVYVGSGGWRFLRIVCKTARRDLFGLSV 60
Query: 61 LIRVRLELRRHQRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLF 120
LIRVRLELRRHQRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLF
Sbjct: 61 LIRVRLELRRHQRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLF 120
Query: 121 RQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALI 180
RQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALI
Sbjct: 121 RQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALI 180
Query: 181 FGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGM 240
FGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGM
Sbjct: 181 FGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGM 240
Query: 241 DDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIG 300
DDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIG
Sbjct: 241 DDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIG 300
Query: 301 VGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRL 360
VGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRL
Sbjct: 301 VGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRL 360
Query: 361 AVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIR 420
AVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIR
Sbjct: 361 AVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIR 420
Query: 421 LVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSV 480
LVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSV
Sbjct: 421 LVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSV 480
Query: 481 FSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVY 540
FSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVY
Sbjct: 481 FSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVY 540
Query: 541 GVAVPGVEGKAGMAAVADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQ 600
GVAVPGVEGKAGMAAVADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQ
Sbjct: 541 GVAVPGVEGKAGMAAVADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQ 600
Query: 601 KTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGAFAL 646
KTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGAFAL
Sbjct: 601 KTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGAFAL 646
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 819 bits (2116), Expect = 0.0
Identities = 398/638 (62%), Positives = 489/638 (76%), Gaps = 2/638 (0%)
Query: 5 GAGAASVVSLALLWLLGLPWTWSAAAALGVYVGSGGWRFLRIVCKTARRDLFGLSVLIRV 64
GA V+ + L +L LPWT + L +Y+GSGGWRF+R+ KT RRD+FG VL++V
Sbjct: 4 GASLVGVLLFSKL-VLKLPWTQVGFSLLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLLKV 62
Query: 65 RLELRRHQRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLG 124
+ ++R+ + T+P +F + V+R P++ AL+ GT WTF QLD YS++VAN + G
Sbjct: 63 KAKVRQCLQERRTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQARG 122
Query: 125 FAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGE 184
A GDV AIF+E R EFVGLWLG+AK G+EAAL+N NLRR+ L CL TS A+AL+FG E
Sbjct: 123 LASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFGSE 182
Query: 185 MVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGMDDRL 244
M +A+ EV L SL FCSG P + P T LDPLLK+A L P KG D+L
Sbjct: 183 MASAICEVHASLDPSLSLFCSGSWEPGAVPPSTEHLDPLLKDAPKH-LPSCPDKGFTDKL 241
Query: 245 FYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQC 304
FYIYTSGTTGLPKAAIVVHSRYYRMAA ++ +RM+ D++YDCLPLYHSAGNI+G+GQC
Sbjct: 242 FYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQC 301
Query: 305 LIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRLAVGN 364
L++G+TVV+RKKFSASRFWDDCIKYNCT+VQYIGE+CRYLL QP REAE +H+VR+A+GN
Sbjct: 302 LLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQHQVRMALGN 361
Query: 365 GLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIRLVKV 424
GLR +IW F+ RF + Q+ EFYGATECNCS+ N D +VG+CGFNSRIL VYPIRLV+V
Sbjct: 362 GLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRV 421
Query: 425 NEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSVFSKG 484
NEDTMEL+R G+CIPCQ GEPG LVG+I Q+DPLRRFDGY+++ A +KKIA VF KG
Sbjct: 422 NEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKG 481
Query: 485 DSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVAV 544
D AYL+GDVLVMDELGY+YFRDR+GDTFRW+GENVSTTEVEG LSRLL DVAVYGV V
Sbjct: 482 DQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEV 541
Query: 545 PGVEGKAGMAAVADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQKTRL 604
PG EG+AGMAAVA P D Q L+K L YARPIFLRLLP++ TGT+K QKT L
Sbjct: 542 PGTEGRAGMAAVASPTGNCDLERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTEL 601
Query: 605 QREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSG 642
++EGFDP D LF+LD ++G Y+PL++ Y+RI +G
Sbjct: 602 RKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAG 639
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 410 bits (1054), Expect = e-114
Identities = 231/526 (43%), Positives = 309/526 (58%), Gaps = 20/526 (3%)
Query: 126 APGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEM 185
+PG VA+ L PEF+ LW GLAKAG+ A + LRR PL CL + GA+AL+ E
Sbjct: 212 SPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARALVLAPEF 271
Query: 186 VAAVA-EVSGHLGKSLIKFCSGDLGPEGILPDTHL--LDPLLKEASTAPLAQIPS----- 237
+ ++ ++ L + +G P TH + LL E S +P
Sbjct: 272 LESLEPDLPALRAMGLHLWAAG--------PGTHPAGISDLLAEVSAEVDGPVPGYLSSP 323
Query: 238 KGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGN 297
+ + D YI+TSGTTGLPKAA + H + + F + + DV+Y LPLYH +G+
Sbjct: 324 QSITDTCLYIFTSGTTGLPKAARISHLKILQCQGF-YQLCGVHQEDVIYLALPLYHMSGS 382
Query: 298 IIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHR 357
++G+ C+ G TVVL+ KFSA +FW+DC ++ TV QYIGE+CRYL+ QP +AER H+
Sbjct: 383 LLGIVGCMGIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQPPSKAERGHK 442
Query: 358 VRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVY 417
VRLAVG+GLRP WE F RFG Q+ E YG TE N + N G+ G+ G S + H++
Sbjct: 443 VRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAVGRASWLYKHIF 502
Query: 418 PIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIA 477
P L++ + T E +RD QG C+ GEPGLLV ++QQ P + G K+
Sbjct: 503 PFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLGYAG--GPELAQGKLL 560
Query: 478 HSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDV 537
VF GD + +GD+LV D+ G++ F DR+GDTFRW+GENV+TTEV V L +V
Sbjct: 561 KDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFEALDFLQEV 620
Query: 538 AVYGVAVPGVEGKAGMAA-VADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGT 596
VYGV VPG EG+AGMAA V P LD +Y + + L PYARP FLRL + TT T
Sbjct: 621 NVYGVTVPGHEGRAGMAALVLRPPHALDLMQLYTHVSENLPPYARPRFLRLQESLATTET 680
Query: 597 FKIQKTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSG 642
FK QK R+ EGFDP SD L+ LD G YLPL A Y+ + +G
Sbjct: 681 FKQQKVRMANEGFDPSTLSDPLYVLDQAVGAYLPLTTARYSALLAG 726
>gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 410 bits (1053), Expect = e-114
Identities = 227/603 (37%), Positives = 354/603 (58%), Gaps = 23/603 (3%)
Query: 54 DLFGLSVLIRVRLELRRHQRAGHTIPRI--FQAVVQRQPERLALVDAGTGECWTFAQLDA 111
D + + ++ + + L+++++ G + + F + +RQP + ++ G + +T+ +D
Sbjct: 30 DFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEG--DIYTYQDVDK 87
Query: 112 YSNAVANLF-RQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFC 170
S+ VA++F GD VA+ + P+FV +W GLAK G A LN N+R L C
Sbjct: 88 RSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNC 147
Query: 171 LGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTA 230
+ G +AL+ G +++ V E+ L +++ + D P+G++ L ++ ST+
Sbjct: 148 IRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVIS-------LKEKLSTS 200
Query: 231 PLAQIPSKG-----MDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVL 285
P +P + YI+TSGTTGLPKAA++ + R +A A+ A D++
Sbjct: 201 PDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAV-LWAFGCTAHDIV 259
Query: 286 YDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLL 345
Y LPLYHS+ I+G+ C+ G T VL+KKFSAS+FW DC KY+ TV QYIGE+CRYL
Sbjct: 260 YITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLC 319
Query: 346 KQPVREAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGS 405
KQ RE E+ H+VRLA+GNG+R +W EF +RFG ++ E Y ATE + S N G++G+
Sbjct: 320 KQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGA 379
Query: 406 CGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDG 465
G + + L+K + E +R+ QG CI + GEPGLL+ ++N ++P F G
Sbjct: 380 IGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNP---FFG 436
Query: 466 YVSE-SATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEV 524
Y T K+ VF KGD +GD++V D+ ++YF DR+GDTFRW+GENV+TTEV
Sbjct: 437 YAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEV 496
Query: 525 EGVLSRLLGQTDVAVYGVAVPGVEGKAGMAA-VADPHSLLDPNAIYQELQKVLAPYARPI 583
V+ L + VYGVA+ G EG+AGMA+ + P++ LD +Y+++ L YA P
Sbjct: 497 ADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPR 556
Query: 584 FLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGA 643
FLR+ +++ TGTFK+ K +L +GF+P + S+ L+F+D + Y+ L +Y +I G
Sbjct: 557 FLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGE 616
Query: 644 FAL 646
L
Sbjct: 617 IKL 619
>gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 410 bits (1053), Expect = e-114
Identities = 227/603 (37%), Positives = 354/603 (58%), Gaps = 23/603 (3%)
Query: 54 DLFGLSVLIRVRLELRRHQRAGHTIPRI--FQAVVQRQPERLALVDAGTGECWTFAQLDA 111
D + + ++ + + L+++++ G + + F + +RQP + ++ G + +T+ +D
Sbjct: 30 DFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEG--DIYTYQDVDK 87
Query: 112 YSNAVANLF-RQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFC 170
S+ VA++F GD VA+ + P+FV +W GLAK G A LN N+R L C
Sbjct: 88 RSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNC 147
Query: 171 LGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTA 230
+ G +AL+ G +++ V E+ L +++ + D P+G++ L ++ ST+
Sbjct: 148 IRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVIS-------LKEKLSTS 200
Query: 231 PLAQIPSKG-----MDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVL 285
P +P + YI+TSGTTGLPKAA++ + R +A A+ A D++
Sbjct: 201 PDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAV-LWAFGCTAHDIV 259
Query: 286 YDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLL 345
Y LPLYHS+ I+G+ C+ G T VL+KKFSAS+FW DC KY+ TV QYIGE+CRYL
Sbjct: 260 YITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLC 319
Query: 346 KQPVREAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGS 405
KQ RE E+ H+VRLA+GNG+R +W EF +RFG ++ E Y ATE + S N G++G+
Sbjct: 320 KQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGA 379
Query: 406 CGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDG 465
G + + L+K + E +R+ QG CI + GEPGLL+ ++N ++P F G
Sbjct: 380 IGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNP---FFG 436
Query: 466 YVSE-SATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEV 524
Y T K+ VF KGD +GD++V D+ ++YF DR+GDTFRW+GENV+TTEV
Sbjct: 437 YAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEV 496
Query: 525 EGVLSRLLGQTDVAVYGVAVPGVEGKAGMAA-VADPHSLLDPNAIYQELQKVLAPYARPI 583
V+ L + VYGVA+ G EG+AGMA+ + P++ LD +Y+++ L YA P
Sbjct: 497 ADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPR 556
Query: 584 FLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGA 643
FLR+ +++ TGTFK+ K +L +GF+P + S+ L+F+D + Y+ L +Y +I G
Sbjct: 557 FLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGE 616
Query: 644 FAL 646
L
Sbjct: 617 IKL 619
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 396 bits (1018), Expect = e-110
Identities = 244/585 (41%), Positives = 324/585 (55%), Gaps = 23/585 (3%)
Query: 72 QRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVAN-LFRQLGFAPGDV 130
+R TI R F ++ P + L+ E T+AQ+D SN VA L LG GD
Sbjct: 49 RRPARTILRAFLEKARQTPHKPFLLFRD--ETLTYAQVDRRSNQVARALHDHLGLRQGDC 106
Query: 131 VAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVA 190
VA+ + P +V LWLGL K G A LN N+R + L C GAK L+ E+ AAV
Sbjct: 107 VALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVE 166
Query: 191 EVSGHLGKS--LIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGMDDRLF--- 245
E+ L K I + S +GI LD + E ST P IP + F
Sbjct: 167 EILPSLKKDDVSIYYVSRTSNTDGI---DSFLDKV-DEVSTEP---IPESWRSEVTFSTP 219
Query: 246 --YIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQ 303
YIYTSGTTGLPKAA++ H R + + ++A DV+Y LP YHSA +IG+
Sbjct: 220 ALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVS-GLKADDVIYITLPFYHSAALLIGIHG 278
Query: 304 CLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRLAVG 363
C++ G T+ LR KFSAS+FWDDC KYN TV+QYIGE+ RYL P + +R H+VRLA+G
Sbjct: 279 CIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALG 338
Query: 364 NGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIRLVK 423
NGLR +W +F +RFG I EFY ATE N N KVG+ G + + + L+K
Sbjct: 339 NGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIK 398
Query: 424 VNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESA-TSKKIAHSVFS 482
+ + E +RD G C+ GE GLLV +I Q P F+GY A T KK VF
Sbjct: 399 YDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTP---FNGYAGAKAQTEKKKLRDVFK 455
Query: 483 KGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGV 542
KGD + SGD+L++D ++YF DR GDTFRW+GENV+TTEV + + +V VYGV
Sbjct: 456 KGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGV 515
Query: 543 AVPGVEGKAGMAAV-ADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQK 601
VP EG+ GMA++ + D ++Q + L YARP FLR+ ++ TGTFK +K
Sbjct: 516 HVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRK 575
Query: 602 TRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGAFAL 646
L EGF+P D L+FLD Y+P+ E +Y I + L
Sbjct: 576 MTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL 620
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 376 bits (965), Expect = e-104
Identities = 256/668 (38%), Positives = 349/668 (52%), Gaps = 39/668 (5%)
Query: 12 VSLALLWLLGLPW-------TWSAAAALGVYVGSG---GWRFLRIVCKTAR--------- 52
V+L L WLLG P A LG +V G L + AR
Sbjct: 29 VALTLRWLLGDPTCCVLLGLAMLARPWLGPWVPHGLSLAAAALALTLLPARLPPGLRWLP 88
Query: 53 RDLFGLSVLIRVRLELRR--HQRAGHTIPRIFQAVVQRQPERLALVDAGTGE-CWTFAQL 109
D+ L+ ++ + L++R ++ T F+ + QP R LV G G TF +L
Sbjct: 89 ADVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGEL 148
Query: 110 DAYS-NAVANLFRQLG----FAPGDVVAIFLEGRPEFVGL--WLGLAKAGMEAALLNVNL 162
DA + A L +LG G+ A+ + L WLGLAK G A +N +
Sbjct: 149 DARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHG 208
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIK-FCSGDLGPEGILPDTHLLD 221
R PLA + +SGA+ L+ ++ ++ E+ L I+ F P P L
Sbjct: 209 RGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPT---PGVGALG 265
Query: 222 PLLKEASTAPLAQIPSKGMDDR--LFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRM 279
L A + P+ G+ R +IYTSGTTGLPK AI+ H R +M+ +
Sbjct: 266 AALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLS-GA 324
Query: 280 QAADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGE 339
A DV+Y LPLYH G ++G+ CL G T VL KFS S FWDDC ++ TV+ Y+GE
Sbjct: 325 TADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGE 384
Query: 340 ICRYLLKQPVREAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANM 399
+ RYL P + +R H VRLA+GNGLR +WE F +RFG +I E YG+TE N + N
Sbjct: 385 LLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNY 444
Query: 400 DGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDP 459
G+ G+ G S +L + P LV+ + + E +RD QG CIP GEPGLL+ ++ Q P
Sbjct: 445 VGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQP 504
Query: 460 LRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENV 519
+ G + +K+ +V GD Y +GDVL MD G++YFRDR GDTFRW+GENV
Sbjct: 505 FVGYRG--PRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENV 562
Query: 520 STTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAV-ADPHSLLDPNAIYQELQKVLAP 578
ST EVEGVLS++ V VYGV VPG EGK GMAAV P D +YQ ++ L
Sbjct: 563 STHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPA 622
Query: 579 YARPIFLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTR 638
YA P F+R+ ++ T TFK+ KTRL REGF+ D LF LD + + PL +Y
Sbjct: 623 YATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQA 682
Query: 639 ICSGAFAL 646
+C G + L
Sbjct: 683 VCEGTWRL 690
>gi|227499621 solute carrier family 27 (fatty acid transporter),
member 2 isoform 2 [Homo sapiens]
Length = 567
Score = 324 bits (831), Expect = 1e-88
Identities = 219/580 (37%), Positives = 290/580 (50%), Gaps = 66/580 (11%)
Query: 72 QRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVAN-LFRQLGFAPGDV 130
+R TI R F ++ P + L+ E T+AQ+D SN VA L LG GD
Sbjct: 49 RRPARTILRAFLEKARQTPHKPFLLFRD--ETLTYAQVDRRSNQVARALHDHLGLRQGDC 106
Query: 131 VAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVA 190
VA+ + P +V LWLGL K G A LN N+R + L C GAK L+ E+ AAV
Sbjct: 107 VALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVE 166
Query: 191 EVSGHLGKS--LIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGMDDRLFYIY 248
E+ L K I + S +GI LD + E ST P IP + F
Sbjct: 167 EILPSLKKDDVSIYYVSRTSNTDGI---DSFLDKV-DEVSTEP---IPESWRSEVTF--- 216
Query: 249 TSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQCLIYG 308
+ LY +Y S G
Sbjct: 217 --------------------------------STPALY----IYTSGTT----------G 230
Query: 309 LTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRLAVGNGLRP 368
T+ LR KFSAS+FWDDC KYN TV+QYIGE+ RYL P + +R H+VRLA+GNGLR
Sbjct: 231 ATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRG 290
Query: 369 AIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIRLVKVNEDT 428
+W +F +RFG I EFY ATE N N KVG+ G + + + L+K + +
Sbjct: 291 DVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEK 350
Query: 429 MELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESA-TSKKIAHSVFSKGDSA 487
E +RD G C+ GE GLLV +I Q P F+GY A T KK VF KGD
Sbjct: 351 DEPVRDENGYCVRVPKGEVGLLVCKITQLTP---FNGYAGAKAQTEKKKLRDVFKKGDLY 407
Query: 488 YLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGV 547
+ SGD+L++D ++YF DR GDTFRW+GENV+TTEV + + +V VYGV VP
Sbjct: 408 FNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDH 467
Query: 548 EGKAGMAAV-ADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQKTRLQR 606
EG+ GMA++ + D ++Q + L YARP FLR+ ++ TGTFK +K L
Sbjct: 468 EGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVE 527
Query: 607 EGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGAFAL 646
EGF+P D L+FLD Y+P+ E +Y I + L
Sbjct: 528 EGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL 567
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 105 bits (263), Expect = 1e-22
Identities = 140/519 (26%), Positives = 213/519 (41%), Gaps = 52/519 (10%)
Query: 104 WTFAQLDAYSNAVANLFR-QLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
W F +L S AN+ G GD VA+ L PE+ + LG +AG+ + +
Sbjct: 81 WNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQM 140
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
+ + + L S AKA++ G E++ V V+ IK + +G L
Sbjct: 141 KSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLN----FKK 196
Query: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAA 282
LL EAST G + +TSGT+GLPK A +S A +QA+
Sbjct: 197 LLNEASTT--HHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQAS 254
Query: 283 DVLY---DCLPLYHSAGNII---GVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQY 336
D+++ D + + G+++ +G C V L KF Y +
Sbjct: 255 DIMWTISDTGWILNILGSLLESWTLGACTF----VHLLPKFDPLVILKTLSSYPIKSMMG 310
Query: 337 IGEICRYLLKQPVREAERRHRVR-LAVGNGLRPAIWEEFTERFGVRQIGEFYGATE--CN 393
+ R LL+Q + + H LA G L P E + + G+ I EFYG TE
Sbjct: 311 APIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL-DIREFYGQTETGLT 369
Query: 394 CSIA-NMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG 452
C ++ M K G G + ++++ D + P G+ G+ V
Sbjct: 370 CMVSKTMKIKPGYMGTAASCY--------------DVQVIDDKGNVLPPGTEGDIGIRVK 415
Query: 453 QINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTF 512
I P+ F GYV K A ++ +GD +L GD + DE GY F R+ D
Sbjct: 416 PIR---PIGIFSGYVE---NPDKTAANI--RGD-FWLLGDRGIKDEDGYFQFMGRADDII 466
Query: 513 RWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLL--DPNAIYQ 570
G + +EVE L + + AV P V G+ A V L DP + +
Sbjct: 467 NSSGYRIGPSEVENALMKHPAVVETAVISSPDP-VRGEVVKAFVILASQFLSHDPEQLTK 525
Query: 571 ELQK----VLAPYARPIFLRLLPQVDTTGTFKIQKTRLQ 605
ELQ+ V APY P + + + T T KIQ+T+L+
Sbjct: 526 ELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 564
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 105 bits (263), Expect = 1e-22
Identities = 140/519 (26%), Positives = 213/519 (41%), Gaps = 52/519 (10%)
Query: 104 WTFAQLDAYSNAVANLFR-QLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
W F +L S AN+ G GD VA+ L PE+ + LG +AG+ + +
Sbjct: 81 WNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQM 140
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
+ + + L S AKA++ G E++ V V+ IK + +G L
Sbjct: 141 KSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLN----FKK 196
Query: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAA 282
LL EAST G + +TSGT+GLPK A +S A +QA+
Sbjct: 197 LLNEASTT--HHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQAS 254
Query: 283 DVLY---DCLPLYHSAGNII---GVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQY 336
D+++ D + + G+++ +G C V L KF Y +
Sbjct: 255 DIMWTISDTGWILNILGSLLESWTLGACTF----VHLLPKFDPLVILKTLSSYPIKSMMG 310
Query: 337 IGEICRYLLKQPVREAERRHRVR-LAVGNGLRPAIWEEFTERFGVRQIGEFYGATE--CN 393
+ R LL+Q + + H LA G L P E + + G+ I EFYG TE
Sbjct: 311 APIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL-DIREFYGQTETGLT 369
Query: 394 CSIA-NMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG 452
C ++ M K G G + ++++ D + P G+ G+ V
Sbjct: 370 CMVSKTMKIKPGYMGTAASCY--------------DVQVIDDKGNVLPPGTEGDIGIRVK 415
Query: 453 QINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTF 512
I P+ F GYV K A ++ +GD +L GD + DE GY F R+ D
Sbjct: 416 PIR---PIGIFSGYVE---NPDKTAANI--RGD-FWLLGDRGIKDEDGYFQFMGRADDII 466
Query: 513 RWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLL--DPNAIYQ 570
G + +EVE L + + AV P V G+ A V L DP + +
Sbjct: 467 NSSGYRIGPSEVENALMKHPAVVETAVISSPDP-VRGEVVKAFVILASQFLSHDPEQLTK 525
Query: 571 ELQK----VLAPYARPIFLRLLPQVDTTGTFKIQKTRLQ 605
ELQ+ V APY P + + + T T KIQ+T+L+
Sbjct: 526 ELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 564
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 99.4 bits (246), Expect = 9e-21
Identities = 137/519 (26%), Positives = 206/519 (39%), Gaps = 52/519 (10%)
Query: 104 WTFAQLDAYSNAVANLFR-QLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
W F +L S AN+ G GD VA+ L PE+ + LG +AG+ + +
Sbjct: 81 WNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQM 140
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
+ + + L S AKA++ G E++ V V+ IK + +G L
Sbjct: 141 KSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLN----FKK 196
Query: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAA 282
LL EAST G + +TSGT+GLPK A +S A +QA+
Sbjct: 197 LLNEASTT--HHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQAS 254
Query: 283 DVLYD------CLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQY 336
D+++ L + S +G C V L KF Y +
Sbjct: 255 DIMWTISDTGWILNILCSLMEPWALGACTF----VHLLPKFDPLVILKTLSSYPIKSMMG 310
Query: 337 IGEICRYLLKQPVREAERRHRVR-LAVGNGLRPAIWEEFTERFGVRQIGEFYGATE--CN 393
+ R LL+Q + + H + VG L P E + + G+ I E YG TE
Sbjct: 311 APIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGL-DIRESYGQTETGLT 369
Query: 394 CSIA-NMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG 452
C ++ M K G G + ++++ D + P G+ G+ V
Sbjct: 370 CMVSKTMKIKPGYMGTAASCY--------------DVQIIDDKGNVLPPGTEGDIGIRVK 415
Query: 453 QINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTF 512
I P+ F GYV K A ++ +GD +L GD + DE GY F R+ D
Sbjct: 416 PIR---PIGIFSGYVD---NPDKTAANI--RGD-FWLLGDRGIKDEDGYFQFMGRADDII 466
Query: 513 RWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLL--DPNAIYQ 570
G + +EVE L + AV P V G+ A V L DP + +
Sbjct: 467 NSSGYRIGPSEVENALMEHPAVVETAVISSPDP-VRGEVVKAFVVLASQFLSHDPEQLTK 525
Query: 571 ELQK----VLAPYARPIFLRLLPQVDTTGTFKIQKTRLQ 605
ELQ+ V APY P + + + T T KIQ+ +L+
Sbjct: 526 ELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLR 564
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 91.7 bits (226), Expect = 2e-18
Identities = 134/519 (25%), Positives = 207/519 (39%), Gaps = 58/519 (11%)
Query: 104 WTFAQLDAYSNAVANLFR-QLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
W F +L S AN+ G GD VA+ L PE+ + LG +AG+ + +
Sbjct: 81 WNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQM 140
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
+ + + L S AKA++ G E++ V V+ IK + +G L
Sbjct: 141 KSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLN----FKK 196
Query: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAA 282
LL EAST G + +TSGT+GLPK A +S A +QA+
Sbjct: 197 LLNEASTT--HHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQAS 254
Query: 283 DVLY---DCLPLYHSAGNII---GVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQY 336
D+++ D + + G+++ +G C V L KF Y +
Sbjct: 255 DIMWTISDTGWILNILGSLLESWTLGACTF----VHLLPKFDPLVILKTLSSYPIKSMMG 310
Query: 337 IGEICRYLLKQPVREAERRHRVR-LAVGNGLRPAIWEEFTERFGVRQIGEFYGATE--CN 393
+ R LL+Q + + H LA G L P E + + G+ I EFYG TE
Sbjct: 311 APIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL-DIREFYGQTETGLT 369
Query: 394 CSIA-NMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG 452
C ++ M K G G Y ++++ + +AG+ G G
Sbjct: 370 CMVSKTMKIKPGYMG----TAASCYDVQVIAFVHGSP-------------RAGDLG-FAG 411
Query: 453 QINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTF 512
+ + K A ++ +GD +L GD + DE GY F R+ D
Sbjct: 412 TMTL--------SFCGHQENPDKTAANI--RGD-FWLLGDRGIKDEDGYFQFMGRADDII 460
Query: 513 RWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLL--DPNAIYQ 570
G + +EVE L + + AV P V G+ A V L DP + +
Sbjct: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDP-VRGEVVKAFVILASQFLSHDPEQLTK 519
Query: 571 ELQK----VLAPYARPIFLRLLPQVDTTGTFKIQKTRLQ 605
ELQ+ V APY P + + + T T KIQ+T+L+
Sbjct: 520 ELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 91.7 bits (226), Expect = 2e-18
Identities = 134/519 (25%), Positives = 207/519 (39%), Gaps = 58/519 (11%)
Query: 104 WTFAQLDAYSNAVANLFR-QLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
W F +L S AN+ G GD VA+ L PE+ + LG +AG+ + +
Sbjct: 81 WNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQM 140
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
+ + + L S AKA++ G E++ V V+ IK + +G L
Sbjct: 141 KSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLN----FKK 196
Query: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAA 282
LL EAST G + +TSGT+GLPK A +S A +QA+
Sbjct: 197 LLNEASTT--HHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQAS 254
Query: 283 DVLY---DCLPLYHSAGNII---GVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQY 336
D+++ D + + G+++ +G C V L KF Y +
Sbjct: 255 DIMWTISDTGWILNILGSLLESWTLGACTF----VHLLPKFDPLVILKTLSSYPIKSMMG 310
Query: 337 IGEICRYLLKQPVREAERRHRVR-LAVGNGLRPAIWEEFTERFGVRQIGEFYGATE--CN 393
+ R LL+Q + + H LA G L P E + + G+ I EFYG TE
Sbjct: 311 APIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL-DIREFYGQTETGLT 369
Query: 394 CSIA-NMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG 452
C ++ M K G G Y ++++ + +AG+ G G
Sbjct: 370 CMVSKTMKIKPGYMG----TAASCYDVQVIAFVHGSP-------------RAGDLG-FAG 411
Query: 453 QINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTF 512
+ + K A ++ +GD +L GD + DE GY F R+ D
Sbjct: 412 TMTL--------SFCGHQENPDKTAANI--RGD-FWLLGDRGIKDEDGYFQFMGRADDII 460
Query: 513 RWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLL--DPNAIYQ 570
G + +EVE L + + AV P V G+ A V L DP + +
Sbjct: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDP-VRGEVVKAFVILASQFLSHDPEQLTK 519
Query: 571 ELQK----VLAPYARPIFLRLLPQVDTTGTFKIQKTRLQ 605
ELQ+ V APY P + + + T T KIQ+T+L+
Sbjct: 520 ELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 91.7 bits (226), Expect = 2e-18
Identities = 129/518 (24%), Positives = 211/518 (40%), Gaps = 46/518 (8%)
Query: 104 WTFAQLDAYSNAVANLFR-QLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
W+F +L S AN+ G PGD + + L PE+ + + + G L
Sbjct: 90 WSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQL 149
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
+ L + L S AK++I + V +S K D G L
Sbjct: 150 TEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLN----FRE 205
Query: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRY-YRMAAFGHHAYRMQA 281
LL+EAST + +K D Y +TSGTTG PK S Y A G +
Sbjct: 206 LLREASTEHNC-MRTKSRDPLAIY-FTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTE 263
Query: 282 ADVLYDCLPL--YHSAGNIIGV---GQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQY 336
+D+ ++ +A + G C+ V + A + K+ T +
Sbjct: 264 SDIFWNTTDTGWVKAAWTLFSAWPNGSCIF----VHELPRVDAKVILNTLSKFPITTLCC 319
Query: 337 IGEICRYLLKQPVREAERRH-RVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCS 395
+ I R L+++ + + + R L G L P + E++ + GV ++ E YG +E
Sbjct: 320 VPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGV-ELYEGYGQSETVVI 378
Query: 396 IANMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQIN 455
AN G G + P Y +++V D +G +P GE G + +I
Sbjct: 379 CANPKGMKIKSGSMGKASPP-YDVQIV-----------DDEGNVLP--PGEEGNVAVRIR 424
Query: 456 QQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWR 515
P F+ Y+ +K A S +GD Y++GD MD+ GY +F R+ D
Sbjct: 425 PTRPFCFFNCYLDNP---EKTAAS--EQGDF-YITGDRARMDKDGYFWFMGRNDDVINSS 478
Query: 516 GENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMA--AVADPHSLLDPNAIYQELQ 573
+ EVE L+ + AV P + G+ A + +S DP A+ +ELQ
Sbjct: 479 SYRIGPVEVESALAEHPAVLESAVVSSPDP-IRGEVVKAFIVLTPAYSSHDPEALTRELQ 537
Query: 574 ----KVLAPYARPIFLRLLPQVDTTGTFKIQKTRLQRE 607
+V APY P + + ++ T + KIQ+++L+ +
Sbjct: 538 EHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQ 575
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 89.0 bits (219), Expect = 1e-17
Identities = 129/519 (24%), Positives = 214/519 (41%), Gaps = 51/519 (9%)
Query: 104 WTFAQLDAYSNAVAN-LFRQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
W+F +L + S AN L + G GD +A+ L PE+ + + + G+ + L
Sbjct: 89 WSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQL 148
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
+ + + L S AK ++ E+ AV + K G L L
Sbjct: 149 TAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGWLSFQELFQF 208
Query: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAF---GHHAYRM 279
+E S G + + +TSGTTG PK A HS+ F G + +
Sbjct: 209 ASEEHSCV------ETGSQEPMTIYFTSGTTGFPKMA--QHSQSSLGIGFTLCGRYWLDL 260
Query: 280 QAADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLRK--KFSASRFWDDCIKYNCTVVQYI 337
+++D++++ I V + G V + + +F F D Y T +
Sbjct: 261 KSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCSP 320
Query: 338 GEICRYLLKQPVREAERRH-RVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSI 396
+ R L+++ ++ + + R L G L P + E++ + G+ ++ E YG TE
Sbjct: 321 PTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTGL-ELYEGYGQTEVGMIC 379
Query: 397 ANMDG---KVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQ 453
AN G K GS G +LP Y ++++ D G +P G+ G + +
Sbjct: 380 ANQKGQEIKPGSMG--KGMLP--YDVQII-----------DENGNVLP--PGKEGEIALR 422
Query: 454 INQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFR 513
+ P F YV +K A ++ +GD Y++GD VMD GY +F R+ D
Sbjct: 423 LKPTRPFCFFSKYVDNP---QKTAATI--RGDF-YVTGDRGVMDSDGYFWFVGRADDVII 476
Query: 514 WRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPG-VEGKAGMAAV--ADPHSLLDPNAIYQ 570
G + EVE L + AV V+ P + G+ A V A P +P +
Sbjct: 477 SSGYRIGPFEVESALIEHPAVVESAV--VSSPDQIRGEVVKAFVVLAAPFKSYNPEKLTL 534
Query: 571 ELQ----KVLAPYARPIFLRLLPQVDTTGTFKIQKTRLQ 605
ELQ K APY P + + ++ T T KI++ L+
Sbjct: 535 ELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLR 573
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 88.2 bits (217), Expect = 2e-17
Identities = 127/521 (24%), Positives = 210/521 (40%), Gaps = 51/521 (9%)
Query: 104 WTFAQLDAYSNAVANLFRQL-GFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
W+F ++ + VAN+F Q G GD +A+ L PE+ + +G + G+ + L
Sbjct: 86 WSFREMGDLTRRVANVFTQTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPATILL 145
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
+ + + + L S AK ++ + + V ++ K D EG L
Sbjct: 146 KAKDILYRLQLSKAKGIVTIDALASEVDSIASQCPSLKTKLLVSDHSREGWLD----FRS 201
Query: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYR-MQA 281
L+K AS + SK +D + + +TSGTTG PK A H + + G R ++
Sbjct: 202 LVKSASPEHTC-VKSKTLDPMVIF-FTSGTTGFPKMAKHSHGLALQPSFPGSRKLRSLKT 259
Query: 282 ADVLYDCLPLYHSAGNIIGVGQCLIY----GLTVVLRK--KFSASRFWDDCIKYNCTVVQ 335
+DV + CL +G I+ L+ G TV + +F +KY
Sbjct: 260 SDVSW-CLS---DSGWIVATIWTLVEPWTAGCTVFIHHLPQFDTKVIIQTLLKYPINHFW 315
Query: 336 YIGEICRYLLKQP---VREAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATEC 392
+ I R +L+Q +R H G + P EE+ R G+ + E YG +E
Sbjct: 316 GVSSIYRMILQQDFTSIRFPALEHCY--TGGEVVLPKDQEEWKRRTGLL-LYENYGQSET 372
Query: 393 NCSIANMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG 452
A G GF + P ++++ D + P G G+ +
Sbjct: 373 GLICATYWGMKIKPGFMGKATPPY-----------DVQVIDDKGSILPPNTEGNIGIRIK 421
Query: 453 QINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTF 512
+ P+ F Y + + K+ F Y +GD MDE GY+ F RS D
Sbjct: 422 PVR---PVSLFMCYEGDPEKTAKVECGDF------YNTGDRGKMDEEGYICFLGRSDDII 472
Query: 513 RWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLL--DPNAIYQ 570
G + EVE L + AV G P + G+ A + L D + + +
Sbjct: 473 NASGYRIGPAEVESALVEHPAVAESAVVGSPDP-IRGEVVKAFIVLTPQFLSHDKDQLTK 531
Query: 571 ELQK----VLAPYARPIFLRLLPQVDTTGTFKIQKTRLQRE 607
ELQ+ V APY P + + ++ T T KI++ L+++
Sbjct: 532 ELQQHVKSVTAPYKYPRKVEFVSELPKTITGKIERKELRKK 572
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 82.4 bits (202), Expect = 1e-15
Identities = 120/498 (24%), Positives = 193/498 (38%), Gaps = 59/498 (11%)
Query: 77 TIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGFAPGDVVAIFLE 136
T+ + + QR PER ALV TFAQL + A+ +G GD + ++
Sbjct: 73 TVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGP 132
Query: 137 GRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGE---------MVA 187
+V + L A+AG+ +N + L + L G KAL+F + +
Sbjct: 133 NSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQ 192
Query: 188 AVAEVS----GHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAP-LAQIPSK---- 238
EV G L + + + + LP T LLD ++ ST L Q+
Sbjct: 193 ICPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFL 252
Query: 239 GMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRM--QAADVLYDCLP--LYHS 294
D + +TSGTTG PK A + H + ++ + + L LP LYH
Sbjct: 253 SCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHC 312
Query: 295 AGNIIGVGQCLIYGLTVVLRKK-FSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAE 353
G++ G CL+YG T++L F+ + + + T + + +L QP +
Sbjct: 313 LGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSY 372
Query: 354 RRHRV--RLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIA-------NMDGKVG 404
+ + G+ P + + ++ + YG TE N + ++ K
Sbjct: 373 DISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTE-NSPVTFAHFPEDTVEQKAE 431
Query: 405 SCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFD 464
S G RI+PH R++ + T+ L LCI G +L
Sbjct: 432 SVG---RIMPHT-EARIMNMEAGTLAKLNTPGELCI---RGYCVML-------------- 470
Query: 465 GYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEV 524
GY E +++ D Y +GDV M+E G+ RS D GEN+ E+
Sbjct: 471 GYWGEPQKTEEAVDQ-----DKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAEL 525
Query: 525 EGVLSRLLGQTDVAVYGV 542
E +V V GV
Sbjct: 526 EDFFHTHPKVQEVQVVGV 543
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 77.8 bits (190), Expect = 3e-14
Identities = 128/560 (22%), Positives = 214/560 (38%), Gaps = 67/560 (11%)
Query: 86 VQRQPERLALV----DAGTGECWTFAQLDAYSNAVANLFRQLGFAPGDVVAIFLEGRPEF 141
V++ PE +AL+ + GT T+ +L + +AN ++ G GD VAI++ P
Sbjct: 119 VRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLA 178
Query: 142 VGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIF------GGEMVAAVAEVSGH 195
V L A+ G ++ E LA + + K +I GG +V V
Sbjct: 179 VAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVD-- 236
Query: 196 LGKSLIKFC---SGDLGPEGILPDTHLLD---PLLKE-ASTAPLAQIPSKGMDDRLFYIY 248
+K C L H+ D PL +E A P+ S G +D LF +Y
Sbjct: 237 ---EAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLY 293
Query: 249 TSGTTGLPKAAIVVHSRYYRMAAFGHH-AYRMQAADVLYDCLPLYHSAGNIIGVGQCLIY 307
TSG+TG+PK + + Y AA H + Q D+ + G+ V L
Sbjct: 294 TSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCN 353
Query: 308 GLTVVLRKKF----SASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRL--- 360
G T VL + +A R+W+ + R LLK ++ R L
Sbjct: 354 GATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTL 413
Query: 361 -AVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPI 419
+VG + WE G + C++ + + + G I P
Sbjct: 414 GSVGEPINCEAWEWLHRVVG-----------DSRCTLVDTWWQTETGGI--CIAP----- 455
Query: 420 RLVKVNEDTMELL-----RDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESAT-- 472
+ +E+ E+L R G+ +P E G +V N L + + T
Sbjct: 456 ---RPSEEGAEILPAMAMRPFFGI-VPVLMDEKGSVVEGSNVSGALCISQAWPGMARTIY 511
Query: 473 --SKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSR 530
++ + F Y +GD E GY R D G + T E+E ++
Sbjct: 512 GDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEIEDAIAD 571
Query: 531 LLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLLDPNAIYQELQKV----LAPYARPIFLR 586
+ AV G ++G+A A + S D + + QEL+ + +A YA P +
Sbjct: 572 HPAVPESAVIGYP-HDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPDEIL 630
Query: 587 LLPQVDTTGTFKIQKTRLQR 606
++ ++ T + K+ + L++
Sbjct: 631 VVKRLPKTRSGKVMRRLLRK 650
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 75.1 bits (183), Expect = 2e-13
Identities = 115/520 (22%), Positives = 202/520 (38%), Gaps = 49/520 (9%)
Query: 104 WTFAQLDAYSNAVANLFRQL-GFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
W+F +L + S AN+ + GD V + L PE+ + + G L
Sbjct: 95 WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
++ + + L +S A +I + AV V+ K + EG L
Sbjct: 155 TQKDILYRLQSSKANCIITNDVLAPAVDAVASKCENLHSKLIVSENSREG----WGNLKE 210
Query: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRY-YRMAAFGHHAYRMQA 281
L+K AS + + +K ++ + +TSGT+G PK HS + ++ G +
Sbjct: 211 LMKHASDSHTC-VKTKH-NEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
Query: 282 ADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLRK--KFSASRFWDDCIKYNCTVVQYIGE 339
+DV+++ + V I G V +F + KY TV
Sbjct: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPT 328
Query: 340 ICRYLLKQPVREAERRHRVR-LAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIAN 398
+ R L++ + + + ++ G + P + E++ + G+ I E YG TE N
Sbjct: 329 VYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGL-DIYEGYGQTETVLICGN 387
Query: 399 MDG---KVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQIN 455
G K GS G S + +++V VN + + P Q G+ G+ Q+
Sbjct: 388 FKGMKIKPGSMGKPSP----AFDVKIVDVNGNVLP----------PGQEGDIGI---QVL 430
Query: 456 QQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWR 515
P F YV + + F Y++GD MD+ GY +F R+ D
Sbjct: 431 PNRPFGLFTHYVDNPSKTASTLRGNF------YITGDRGYMDKDGYFWFVARADDVILSS 484
Query: 516 GENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVA--------DPHSLLDPNA 567
G + EVE L+ + AV P + G+ A V D L+
Sbjct: 485 GYRIGPFEVENALNEHPSVAESAVVSSPDP-IRGEVVKAFVVLNPDYKSHDQEQLI--KE 541
Query: 568 IYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQKTRLQRE 607
I + ++K APY P + + ++ T + K ++ L+++
Sbjct: 542 IQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKK 581
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 71.2 bits (173), Expect = 3e-12
Identities = 101/393 (25%), Positives = 155/393 (39%), Gaps = 29/393 (7%)
Query: 235 IPSKGMDDR-LFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYH 293
+P +G ++ IYTSGTTG PK + H + H + DV+ LPL+H
Sbjct: 187 VPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHH 246
Query: 294 SAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKY---NCTVVQYIGEICRYLLKQPVR 350
G + + L G T V+ +FS + W+ + V + I L++ R
Sbjct: 247 VHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDR 306
Query: 351 EAERRH-----------RVRLAV-GNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIAN 398
+ H ++RL V G+ P E + + E YG TE +++
Sbjct: 307 HFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSG 366
Query: 399 -MDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG---QI 454
+ V G LP V +R+V N R+A I + E G V +
Sbjct: 367 PLTTAVRLPGSVGTPLPGV-QVRIVSENPQ-----REACSYTIHAEGDERGTKVTPGFEE 420
Query: 455 NQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRW 514
+ + L R E + S F+ D + +GD +V + Y S D +
Sbjct: 421 KEGELLVRGPSVFREYWNKPEETKSAFTL-DGWFKTGDTVVFKDGQYWIRGRTSVDIIKT 479
Query: 515 RGENVSTTEVEGVLSRLLGQTDVAVYGVA-VPGVEGKAGMAAVADPHSLLDPNAIYQELQ 573
G VS EVE L TDVAV GV + + + + + HS L + + +
Sbjct: 480 GGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHS-LSHRELKEWAR 538
Query: 574 KVLAPYARPIFLRLLPQVDTTGTFKIQKTRLQR 606
VLAPYA P L L+ ++ KI K L R
Sbjct: 539 NVLAPYAVPSELVLVEEIPRNQMGKIDKKALIR 571
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 71.2 bits (173), Expect = 3e-12
Identities = 101/393 (25%), Positives = 155/393 (39%), Gaps = 29/393 (7%)
Query: 235 IPSKGMDDR-LFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYH 293
+P +G ++ IYTSGTTG PK + H + H + DV+ LPL+H
Sbjct: 187 VPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHH 246
Query: 294 SAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKY---NCTVVQYIGEICRYLLKQPVR 350
G + + L G T V+ +FS + W+ + V + I L++ R
Sbjct: 247 VHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDR 306
Query: 351 EAERRH-----------RVRLAV-GNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIAN 398
+ H ++RL V G+ P E + + E YG TE +++
Sbjct: 307 HFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSG 366
Query: 399 -MDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG---QI 454
+ V G LP V +R+V N R+A I + E G V +
Sbjct: 367 PLTTAVRLPGSVGTPLPGV-QVRIVSENPQ-----REACSYTIHAEGDERGTKVTPGFEE 420
Query: 455 NQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRW 514
+ + L R E + S F+ D + +GD +V + Y S D +
Sbjct: 421 KEGELLVRGPSVFREYWNKPEETKSAFTL-DGWFKTGDTVVFKDGQYWIRGRTSVDIIKT 479
Query: 515 RGENVSTTEVEGVLSRLLGQTDVAVYGVA-VPGVEGKAGMAAVADPHSLLDPNAIYQELQ 573
G VS EVE L TDVAV GV + + + + + HS L + + +
Sbjct: 480 GGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHS-LSHRELKEWAR 538
Query: 574 KVLAPYARPIFLRLLPQVDTTGTFKIQKTRLQR 606
VLAPYA P L L+ ++ KI K L R
Sbjct: 539 NVLAPYAVPSELVLVEEIPRNQMGKIDKKALIR 571
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 67.0 bits (162), Expect = 5e-11
Identities = 126/570 (22%), Positives = 208/570 (36%), Gaps = 92/570 (16%)
Query: 105 TFAQLDAYSNAVANLFRQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRR 164
T+ QL +N+ R+ G GD VAI++ PE V L A+ G +++
Sbjct: 137 TYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSS 196
Query: 165 EPLAFCLGTSGAKALI-----FGGEMVAAVAEVSG--------------------HLGKS 199
E L + S LI + GE + + E++ HLG++
Sbjct: 197 ESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRA 256
Query: 200 LIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIP-SKGMD----------------- 241
+ I + LKE S QI ++G+D
Sbjct: 257 ELGMGDSTSQSPPIKRSCPDVQGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPE 316
Query: 242 -----DRLFYIYTSGTTGLPKAAIVVHSRYYR-MAAFGHHAYRMQAADVLYDCLPLYHSA 295
D LF +YTSG+TG PK + Y +A + + A DV + +
Sbjct: 317 WCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWIT 376
Query: 296 GNIIGVGQCLIYGLTVVLRKKF----SASRFWDDCIKYNCTVVQYIGEICRYLLK---QP 348
G+ L G T VL + +R W KY T R L+K +P
Sbjct: 377 GHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEP 436
Query: 349 VREAERRH-RVRLAVGNGLRPAIWEEFTERFGVRQ---IGEFYGATECNCSIANMDG--- 401
V + R +V VG + P W + G ++ + F+ + + G
Sbjct: 437 VTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATP 496
Query: 402 -KVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPL 460
K GS F + + +NE EL +A+G + Q PG++ +
Sbjct: 497 MKPGSATFP------FFGVAPAILNESGEELEGEAEGYLVFKQPW-PGIMRTVYGNHE-- 547
Query: 461 RRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVS 520
RF+ + F K Y++GD D+ GY + R D G +S
Sbjct: 548 -RFET-------------TYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLS 593
Query: 521 TTEVEGVLSRLLGQTDVAVYGVAVPGVEGKA--GMAAVADPHSLLD--PNAIYQELQKVL 576
T EVE L + AV G P V+G+ + D H+ + +++++ +
Sbjct: 594 TAEVESALVEHEAVAEAAVVGHPHP-VKGECLYCFVTLCDGHTFSPKLTEELKKQIREKI 652
Query: 577 APYARPIFLRLLPQVDTTGTFKIQKTRLQR 606
P A P +++ P + T + KI + L++
Sbjct: 653 GPIATPDYIQNAPGLPKTRSGKIMRRVLRK 682
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 65.9 bits (159), Expect = 1e-10
Identities = 127/570 (22%), Positives = 212/570 (37%), Gaps = 105/570 (18%)
Query: 105 TFAQLDAYSNAVANLFRQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRR 164
T+ QL +N+ R+ G GD VAI++ PE V L A+ G +++
Sbjct: 137 TYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSS 196
Query: 165 EPLAFCLGTSGAKALI-----FGGEMVAAVAEVSG--------------------HLGKS 199
E L + S LI + GE + + E++ HLG++
Sbjct: 197 ESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRA 256
Query: 200 LIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIP-SKGMD----------------- 241
+LG + D+ P +K + P QI ++G+D
Sbjct: 257 -------ELG----MGDSTSQSPPIKRS--CPDVQISWNQGIDLWWHELMQEAGDECEPE 303
Query: 242 -----DRLFYIYTSGTTGLPKAAIVVHSRYYR-MAAFGHHAYRMQAADVLYDCLPLYHSA 295
D LF +YTSG+TG PK + Y +A + + A DV + +
Sbjct: 304 WCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWIT 363
Query: 296 GNIIGVGQCLIYGLTVVLRKKF----SASRFWDDCIKYNCTVVQYIGEICRYLLK---QP 348
G+ L G T VL + +R W KY T R L+K +P
Sbjct: 364 GHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEP 423
Query: 349 VREAERRH-RVRLAVGNGLRPAIWEEFTERFGVRQ---IGEFYGATECNCSIANMDG--- 401
V + R +V VG + P W + G ++ + F+ + + G
Sbjct: 424 VTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATP 483
Query: 402 -KVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPL 460
K GS F + + +NE EL +A+G + Q PG++ +
Sbjct: 484 MKPGSATFP------FFGVAPAILNESGEELEGEAEGYLVFKQPW-PGIMRTVYGNHE-- 534
Query: 461 RRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVS 520
RF+ + F K Y++GD D+ GY + R D G +S
Sbjct: 535 -RFET-------------TYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLS 580
Query: 521 TTEVEGVLSRLLGQTDVAVYGVAVPGVEGKA--GMAAVADPHSLLD--PNAIYQELQKVL 576
T EVE L + AV G P V+G+ + D H+ + +++++ +
Sbjct: 581 TAEVESALVEHEAVAEAAVVGHPHP-VKGECLYCFVTLCDGHTFSPKLTEELKKQIREKI 639
Query: 577 APYARPIFLRLLPQVDTTGTFKIQKTRLQR 606
P A P +++ P + T + KI + L++
Sbjct: 640 GPIATPDYIQNAPGLPKTRSGKIMRRVLRK 669
>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
sapiens]
Length = 480
Score = 51.2 bits (121), Expect = 3e-06
Identities = 92/432 (21%), Positives = 163/432 (37%), Gaps = 43/432 (9%)
Query: 99 GTGECWTFAQLDAYSNAVANLFRQL-GFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAAL 157
G + W+F ++ S A++ + GD + I L PE + L + G+
Sbjct: 81 GEEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVP 140
Query: 158 LNVNLRREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDT 217
+ L + + + L S A+ ++ M V K D +G L
Sbjct: 141 GSPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFK 200
Query: 218 HLLDPLLKEASTAPLAQ--IPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHH 275
L+ AP Q + +K D + +T GTTG PK +V +S+Y F
Sbjct: 201 KLIQ-------VAPPKQTYMRTKSQDPMAIF-FTKGTTGAPK--MVEYSQYGLGMGFSQA 250
Query: 276 AYR---MQAADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVL--RKKFSASRFWDDCIKYN 330
+ R +Q DVL+ + + ++ V G V L F + ++
Sbjct: 251 SRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFP 310
Query: 331 CTVVQYIGEICRYLLKQPVREAERRHRVR--LAVGNGLRPAIWEEFTERFGVRQIGEFYG 388
T + E+ + LL+ + R ++ +A G + P + E++ +R I E YG
Sbjct: 311 ITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEGYG 369
Query: 389 ATECNCSIANMDG-KVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEP 447
TE A K+ + P++ V++ ++ LL GE
Sbjct: 370 QTETGLLCATSKTIKLKPSSLGKPLPPYI-----VQIVDENSNLL----------PPGEE 414
Query: 448 GLLVGQINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDR 507
G + +I P Y + ++ A + +G YL+GD +MDE GY ++ R
Sbjct: 415 GNIAIRIKLNQPASL---YCPHMVSWEEYASA---RGHMLYLTGDRGIMDEDGYFWWSGR 468
Query: 508 SGDTFRWRGENV 519
D G+ +
Sbjct: 469 VDDVANALGQRL 480
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 44.3 bits (103), Expect = 4e-04
Identities = 69/312 (22%), Positives = 122/312 (39%), Gaps = 15/312 (4%)
Query: 104 WTFAQLDAYSNAVANLFRQL-GFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
W+F +L + S AN+ + GD V + L PE+ + + G L
Sbjct: 95 WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
Query: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
++ + + L +S A +I + AV V+ K + EG L
Sbjct: 155 TQKDILYRLQSSKANCIITNDVLAPAVDAVASKCENLHSKLIVSENSREG----WGNLKE 210
Query: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRY-YRMAAFGHHAYRMQA 281
L+K AS + + +K ++ + +TSGT+G PK HS + ++ G +
Sbjct: 211 LMKHASDSHTC-VKTKH-NEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
Query: 282 ADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLR--KKFSASRFWDDCIKYNCTVVQYIGE 339
+DV+++ + V I G V +F + KY TV
Sbjct: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPT 328
Query: 340 ICRYLLKQPVREAE-RRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIAN 398
+ R L++ + + + + ++ G + P + E++ + G+ I E YG TE N
Sbjct: 329 VYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGL-DIYEGYGQTETVLICGN 387
Query: 399 MDG---KVGSCG 407
G K GS G
Sbjct: 388 FKGMKIKPGSMG 399
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 40.8 bits (94), Expect = 0.004
Identities = 53/200 (26%), Positives = 75/200 (37%), Gaps = 27/200 (13%)
Query: 126 APGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEM 185
+P V IF + RPE++ L M A L L E + + + +I
Sbjct: 130 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 189
Query: 186 VAAVAEVSGHLGKS---------LIKFCSGDLGPEGILPDTHLL-----DPLLKEASTAP 231
A V + G++ K L+ DL G +L + L KE P
Sbjct: 190 KALV--LIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKP 247
Query: 232 LAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAA----FGHHAYRMQAADVLYD 287
+ P +D +TSGTTG PK A++ H AA HAY DV
Sbjct: 248 VPPSP----EDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAIS 303
Query: 288 CLPLYHSAGNIIGVGQCLIY 307
LPL H I+ Q ++Y
Sbjct: 304 YLPLAHMFERIV---QAVVY 320
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 40.8 bits (94), Expect = 0.004
Identities = 53/200 (26%), Positives = 75/200 (37%), Gaps = 27/200 (13%)
Query: 126 APGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEM 185
+P V IF + RPE++ L M A L L E + + + +I
Sbjct: 130 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 189
Query: 186 VAAVAEVSGHLGKS---------LIKFCSGDLGPEGILPDTHLL-----DPLLKEASTAP 231
A V + G++ K L+ DL G +L + L KE P
Sbjct: 190 KALV--LIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKP 247
Query: 232 LAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAA----FGHHAYRMQAADVLYD 287
+ P +D +TSGTTG PK A++ H AA HAY DV
Sbjct: 248 VPPSP----EDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAIS 303
Query: 288 CLPLYHSAGNIIGVGQCLIY 307
LPL H I+ Q ++Y
Sbjct: 304 YLPLAHMFERIV---QAVVY 320
>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
a [Homo sapiens]
Length = 739
Score = 40.8 bits (94), Expect = 0.004
Identities = 53/200 (26%), Positives = 75/200 (37%), Gaps = 27/200 (13%)
Query: 126 APGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEM 185
+P V IF + RPE++ L M A L L E + + + +I
Sbjct: 186 SPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQ 245
Query: 186 VAAVAEVSGHLGKS---------LIKFCSGDLGPEGILPDTHLL-----DPLLKEASTAP 231
A V + G++ K L+ DL G +L + L KE P
Sbjct: 246 KALV--LIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKP 303
Query: 232 LAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAA----FGHHAYRMQAADVLYD 287
+ P +D +TSGTTG PK A++ H AA HAY DV
Sbjct: 304 VPPSP----EDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAIS 359
Query: 288 CLPLYHSAGNIIGVGQCLIY 307
LPL H I+ Q ++Y
Sbjct: 360 YLPLAHMFERIV---QAVVY 376
>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
[Homo sapiens]
Length = 670
Score = 36.2 bits (82), Expect = 0.096
Identities = 41/151 (27%), Positives = 62/151 (41%), Gaps = 11/151 (7%)
Query: 123 LGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFG 182
LG P + +AIF E R E++ K L L +E + L S A LI
Sbjct: 104 LGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITS 163
Query: 183 GEMV-----AAVAEVS--GHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQI 235
E++ A+ ++S H+ K + PEG + H + + + S I
Sbjct: 164 VELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGF--EIHSMQSVEELGSNPENLGI 221
Query: 236 PSKGM--DDRLFYIYTSGTTGLPKAAIVVHS 264
P D +YTSG+TG PK ++ HS
Sbjct: 222 PPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 252
>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
2 [Homo sapiens]
Length = 711
Score = 36.2 bits (82), Expect = 0.096
Identities = 41/151 (27%), Positives = 62/151 (41%), Gaps = 11/151 (7%)
Query: 123 LGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFG 182
LG P + +AIF E R E++ K L L +E + L S A LI
Sbjct: 145 LGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITS 204
Query: 183 GEMV-----AAVAEVS--GHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQI 235
E++ A+ ++S H+ K + PEG + H + + + S I
Sbjct: 205 VELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGF--EIHSMQSVEELGSNPENLGI 262
Query: 236 PSKGM--DDRLFYIYTSGTTGLPKAAIVVHS 264
P D +YTSG+TG PK ++ HS
Sbjct: 263 PPSRPTPSDMAIVMYTSGSTGRPKGVMMHHS 293
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,617,010
Number of Sequences: 37866
Number of extensions: 1030875
Number of successful extensions: 2034
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1938
Number of HSP's gapped (non-prelim): 50
length of query: 646
length of database: 18,247,518
effective HSP length: 109
effective length of query: 537
effective length of database: 14,120,124
effective search space: 7582506588
effective search space used: 7582506588
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.