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Search of human proteins with 124256489
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124256489 crooked neck-like 1 protein [Homo sapiens]
(848 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124256489 crooked neck-like 1 protein [Homo sapiens] 1721 0.0
gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo sapi... 91 6e-18
gi|55770906 XPA binding protein 2 [Homo sapiens] 78 4e-14
gi|4557495 cleavage stimulation factor subunit 3 isoform 1 [Homo... 73 1e-12
gi|70980549 programmed cell death 11 [Homo sapiens] 65 3e-10
gi|169172639 PREDICTED: similar to U5 snRNP-associated 102 kDa p... 61 4e-09
gi|49574529 hepatocellular carcinoma-associated antigen 66 [Homo... 60 9e-09
gi|7661952 squamous cell carcinoma antigen recognized by T cells... 52 2e-06
gi|83415184 transmembrane and tetratricopeptide repeat containin... 50 1e-05
gi|156938331 PRP39 pre-mRNA processing factor 39 homolog [Homo s... 44 5e-04
gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens] 41 0.004
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 38 0.045
gi|39932581 hypothetical protein LOC55051 isoform 2 [Homo sapiens] 38 0.045
gi|39932583 hypothetical protein LOC55051 isoform 1 [Homo sapiens] 38 0.045
gi|75709187 cleavage stimulation factor subunit 3 isoform 2 [Hom... 37 0.10
gi|96975038 coiled-coil domain containing 100 [Homo sapiens] 36 0.13
gi|17149828 NMDA receptor regulated 1 [Homo sapiens] 36 0.13
gi|88759339 aster-associated protein [Homo sapiens] 35 0.22
gi|148746195 trichohyalin [Homo sapiens] 35 0.29
gi|225690497 tight junction associated protein 1 isoform b [Homo... 35 0.29
gi|225690495 tight junction associated protein 1 isoform b [Homo... 35 0.29
gi|225690493 tight junction associated protein 1 isoform b [Homo... 35 0.29
gi|225690491 tight junction associated protein 1 isoform b [Homo... 35 0.29
gi|225690489 tight junction associated protein 1 isoform a [Homo... 35 0.29
gi|225690487 tight junction associated protein 1 isoform a [Homo... 35 0.29
gi|156104908 myosin heavy chain 6 [Homo sapiens] 35 0.29
gi|221219020 NYD-SP11 protein [Homo sapiens] 35 0.38
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 35 0.38
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 34 0.50
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 34 0.65
>gi|124256489 crooked neck-like 1 protein [Homo sapiens]
Length = 848
Score = 1721 bits (4457), Expect = 0.0
Identities = 848/848 (100%), Positives = 848/848 (100%)
Query: 1 MTATVENLTFQKDTLGNAVDKNTSRLELRSYSLAGRHGSTEPLVLAWSSQFRRLTWGCAL 60
MTATVENLTFQKDTLGNAVDKNTSRLELRSYSLAGRHGSTEPLVLAWSSQFRRLTWGCAL
Sbjct: 1 MTATVENLTFQKDTLGNAVDKNTSRLELRSYSLAGRHGSTEPLVLAWSSQFRRLTWGCAL 60
Query: 61 DALHRSPCVAASQHGVTHLIRSSRTPHSTRCRKEDAQPGHHGNGAASVTAQARGQRSVLQ 120
DALHRSPCVAASQHGVTHLIRSSRTPHSTRCRKEDAQPGHHGNGAASVTAQARGQRSVLQ
Sbjct: 61 DALHRSPCVAASQHGVTHLIRSSRTPHSTRCRKEDAQPGHHGNGAASVTAQARGQRSVLQ 120
Query: 121 VPLPVPRSCLFSESFVVSVSSQSRFLASVPGTGVQRSTAADMAASTAAGKQRIPKVAKVK 180
VPLPVPRSCLFSESFVVSVSSQSRFLASVPGTGVQRSTAADMAASTAAGKQRIPKVAKVK
Sbjct: 121 VPLPVPRSCLFSESFVVSVSSQSRFLASVPGTGVQRSTAADMAASTAAGKQRIPKVAKVK 180
Query: 181 NKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRT 240
NKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRT
Sbjct: 181 NKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRT 240
Query: 241 VISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWD 300
VISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWD
Sbjct: 241 VISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWD 300
Query: 301 RAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVD 360
RAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVD
Sbjct: 301 RAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVD 360
Query: 361 RARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFA 420
RARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFA
Sbjct: 361 RARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFA 420
Query: 421 KFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQY 480
KFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQY
Sbjct: 421 KFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQY 480
Query: 481 EEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINY 540
EEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINY
Sbjct: 481 EEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINY 540
Query: 541 ALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSI 600
ALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSI
Sbjct: 541 ALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSI 600
Query: 601 GKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRAR 660
GKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRAR
Sbjct: 601 GKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRAR 660
Query: 661 AIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFEL 720
AIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFEL
Sbjct: 661 AIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFEL 720
Query: 721 SSGKEGSLTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPE 780
SSGKEGSLTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPE
Sbjct: 721 SSGKEGSLTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPE 780
Query: 781 KVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLLAMAKLWKKQQQEKEDAEHHPD 840
KVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLLAMAKLWKKQQQEKEDAEHHPD
Sbjct: 781 KVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLLAMAKLWKKQQQEKEDAEHHPD 840
Query: 841 EDVDESES 848
EDVDESES
Sbjct: 841 EDVDESES 848
>gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo
sapiens]
Length = 941
Score = 90.5 bits (223), Expect = 6e-18
Identities = 113/502 (22%), Positives = 222/502 (44%), Gaps = 52/502 (10%)
Query: 245 WIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAIT 304
WI A+ EE ++Q AR++ + ++ ++ +WL+ A ++ + A+ + +A+
Sbjct: 312 WIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDT----AKAVVAQAVR 367
Query: 305 TLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEE-QAWHSYINFELRYKEVDRAR 363
LP+ + + + +E ++ ++V + +E P + W + + E E + AR
Sbjct: 368 HLPQSVRIYIRAAELET---DIRAKKRVLRKALEHVPNSVRLWKAAVELE----EPEDAR 420
Query: 364 TIYERFVLVHP-DVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKF 422
+ R V P V+ W+ AR E + +ARKV +A E + D H+++ AK
Sbjct: 421 IMLSRAVECCPTSVELWLALARLET----YENARKVLNKARE---NIPTDRHIWITAAKL 473
Query: 423 EENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRG----IEDIIVSKRRF 478
EE + V I A+ + + + E+ + I + + DR G + ++ +
Sbjct: 474 EEANGNTQMVEKIIDRAITSL-RANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGI 532
Query: 479 QYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWI 538
EEE + + W + + E R +Y A+ P +K W R Y
Sbjct: 533 GIEEEDRKH-----TWMEDADSCVAHNALECARAIYAYALQVFP--SKKSVWLRAAYFEK 585
Query: 539 NYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGT 598
N+ E LEA + Q ++ P + +W++ A+ + ++ AR L
Sbjct: 586 NHGTRESLEA--------LLQRAVAHCPKAEV----LWLMGAKSKWLAGDVPAARSILAL 633
Query: 599 SIGKCPKN-KLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDID 657
+ P + +++ ++LE + E++R R+L K P ++K +LE + +I
Sbjct: 634 AFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAP-TARVFMKSVKLEWVQDNIR 692
Query: 658 RARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQH-VKVWISFA 716
A+ + E A+ D P+ LW E ++E E+ R Y + L++ H +W+ +
Sbjct: 693 AAQDLCEEALRHYE-DFPK-LWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLS 750
Query: 717 QFELSSGKEGSLTKCRQIYEEA 738
+ E K G LT+ R I E++
Sbjct: 751 RLE---EKIGQLTRARAILEKS 769
Score = 45.8 bits (107), Expect = 2e-04
Identities = 43/214 (20%), Positives = 89/214 (41%), Gaps = 5/214 (2%)
Query: 189 ITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKY 248
I A Q L E R E P K EE+ + + R+ + ++K W+
Sbjct: 691 IRAAQDLCEEALRHYEDFPKLWMMKGQIEEQ-KEMMEKAREAYNQGLKKCPHSTPLWLLL 749
Query: 249 AQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPR 308
++ EE + ++ RAR+I E++ + +N LWL+ +E + N A + +A+ P
Sbjct: 750 SRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPN 809
Query: 309 VNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYER 368
W + ++E + + + + + + +++ +AR + R
Sbjct: 810 SGILWSEAIFLE---ARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHR 866
Query: 369 FVLVHPDVKN-WIKYARFEEKHAYFAHARKVYER 401
V + D+ + W + +FE +H +V +R
Sbjct: 867 TVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKR 900
>gi|55770906 XPA binding protein 2 [Homo sapiens]
Length = 855
Score = 77.8 bits (190), Expect = 4e-14
Identities = 116/619 (18%), Positives = 233/619 (37%), Gaps = 114/619 (18%)
Query: 231 FEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNR 290
+E+ I +N+ + W++Y ++++ + R +YERAL + + LW +Y ++ +
Sbjct: 24 YEEEIMRNQFSVKCWLRYIEFKQGAPK-PRLNQLYERALKLLPCSYKLWYRY--LKARRA 80
Query: 291 QVNH----------ARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQ 340
QV H N +RA + ++ + W Y G V R+ F+R +
Sbjct: 81 QVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRAL 140
Query: 341 P---EEQAWHSYINFELRYKEVDRARTIYERFVLVHPD-VKNWIKYARFEEKHAYFAHAR 396
P + W Y+ F + + A Y RF+ + P+ + +I+Y + ++ A
Sbjct: 141 PITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRL 200
Query: 397 KVY---ERAVEFFGDEHMD------------------------------------EHLYV 417
ER V G + L+
Sbjct: 201 ATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWC 260
Query: 418 AFAKFEENQKEFERVRVIYKYALDRI-SKQDAQELFKNYTIFEKKF----------GDRR 466
+ A + FE+ R +Y+ A+ + + +D ++F +Y FE+ R
Sbjct: 261 SLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGRE 320
Query: 467 GIEDIIVSKRRFQYEEEV------------KANPHNYDAWFDYLRLVESDAEAEAVREVY 514
+D+ + R ++E+ + + NPH+ W + R+ + Y
Sbjct: 321 EEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEW--HKRVALHQGRPREIINTY 378
Query: 515 ERAIANVPPIQE--KRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTF 572
A+ V P + K H LW+ +A + E + + R + + + ++ +
Sbjct: 379 TEAVQTVDPFKATGKPH-----TLWVAFAKFYE-DNGQLDDARVILEKATKVNFKQVDDL 432
Query: 573 AKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKF 632
A +W + E+R +N A R L + + + FD + +
Sbjct: 433 ASVWCQCGELELRHENYDEALRLLRKATALPARRAEY------------FDGSEPVQNRV 480
Query: 633 LEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEET 692
++ W A+LE LG +A+Y+ I R+ P+++ +Y F E +
Sbjct: 481 Y----KSLKVWSMLADLEESLGTFQSTKAVYD-RILDLRIATPQIV-INYAMFLEEHKYF 534
Query: 693 ERTRNLYRR---LLQRTQHVKVWISFAQFELSSGKEGSLTKCRQIYEEANKTMRNCEEKE 749
E + Y R L + +W ++ ++ L + R ++E+A + C K
Sbjct: 535 EESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQA---LDGCPPKY 591
Query: 750 ERLMLLESWRSFEEEFGTA 768
+ + L + EEE+G A
Sbjct: 592 AKTLYL-LYAQLEEEWGLA 609
Score = 75.5 bits (184), Expect = 2e-13
Identities = 134/589 (22%), Positives = 228/589 (38%), Gaps = 127/589 (21%)
Query: 220 LNDYKLRK------RKTFEDNIRKNRTV---ISNWIKYAQWEESL--KEIQRARSIYERA 268
L DY +R R +E+ IR TV + YAQ+EES+ +++ A +
Sbjct: 262 LADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREE 321
Query: 269 LDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTL--PRVNQFWYKYTYME-----E 321
D ++ L L+ A E Q+ R + ++ P W+K + E
Sbjct: 322 ED----DVDLELRLARFE----QLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPRE 373
Query: 322 MLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYER-----FVLVHPDV 376
++ A Q + + W ++ F ++D AR I E+ F V
Sbjct: 374 IINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLA 433
Query: 377 KNWIKYARFEEKHAYFAHARKVYERAV-------EFF-GDEHMDEHLYVAF------AKF 422
W + E +H + A ++ +A E+F G E + +Y + A
Sbjct: 434 SVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADL 493
Query: 423 EENQKEFERVRVIYKYALD-RISKQDAQELFKNYTIF--EKKFGDRRGIEDIIVSKRRFQ 479
EE+ F+ + +Y LD RI+ ++ NY +F E K+
Sbjct: 494 EESLGTFQSTKAVYDRILDLRIA---TPQIVINYAMFLEEHKY----------------- 533
Query: 480 YEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWIN 539
+EE KA YER I+ W Y+ +I
Sbjct: 534 FEESFKA---------------------------YERGISLFKWPNVSDIWSTYLTKFI- 565
Query: 540 YALYEELEAKDPERTRQVYQASLELIPHKKFTFAK-MWILYAQFEIRQKNLSLARRALGT 598
+ ER R +++ +L+ P K +AK +++LYAQ E + LAR A+
Sbjct: 566 ----ARYGGRKLERARDLFEQALDGCPPK---YAKTLYLLYAQLE---EEWGLARHAMAV 615
Query: 599 ------SIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEF-----GPENCTSWIKFA 647
++ + +F +YI+ ++ R +Y+K +E E C ++FA
Sbjct: 616 YERATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMC---LRFA 672
Query: 648 ELETILGDIDRARAIYELA--ISQPRLDMPEVLWKSYIDFEIE--QEETERTRNLYRRLL 703
++E LG+IDRARAIY I PR W+++ DFE+ E+T + RR +
Sbjct: 673 DMECKLGEIDRARAIYSFCSQICDPR--TTGAFWQTWKDFEVRHGNEDTIKEMLRIRRSV 730
Query: 704 QRTQHVKVWISFAQFELSSGKEGSLTKCRQIYEEANKTMRNCEEKEERL 752
Q T + +V +Q SG + M+ E++ E+L
Sbjct: 731 QATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQL 779
Score = 62.0 bits (149), Expect = 2e-09
Identities = 66/309 (21%), Positives = 127/309 (41%), Gaps = 33/309 (10%)
Query: 470 DIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRH 529
D++ + YEEE+ N + W Y+ + A + ++YERA+ +P +
Sbjct: 14 DLVFEEEDLPYEEEIMRNQFSVKCWLRYIEF-KQGAPKPRLNQLYERALKLLPCSYK--- 69
Query: 530 WKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTF----AKMWILYAQFEIR 585
LW Y + K T Y+ + + F F ++W+ Y QF +
Sbjct: 70 ------LWYRYLKARRAQVKHRCVTDPAYE-DVNNCHERAFVFMHKMPRLWLDYCQFLMD 122
Query: 586 QKNLSLARRALGTSIGKCP---KNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTS 642
Q ++ RR ++ P ++++ +Y+ + + Y +FL+ PE+
Sbjct: 123 QGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEE 182
Query: 643 WIKFAELETILGDIDRARAIY---ELAISQPRLDMPEVLWKSYIDFEIEQEETERTRN-- 697
+I++ + L + + A E +S+ + LW D + + ++ N
Sbjct: 183 YIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQ-LWHELCDLISQNPDKVQSLNVD 241
Query: 698 -LYRRLLQR--TQHVKVWISFAQFELSSGKEGSLTKCRQIYEEANKTMRNCEEKEERLML 754
+ R L R Q K+W S A + + S G K R +YEEA +T+ + + +
Sbjct: 242 AIIRGGLTRFTDQLGKLWCSLADYYIRS---GHFEKARDVYEEAIRTVMTVRDFTQ---V 295
Query: 755 LESWRSFEE 763
+S+ FEE
Sbjct: 296 FDSYAQFEE 304
>gi|4557495 cleavage stimulation factor subunit 3 isoform 1 [Homo
sapiens]
Length = 717
Score = 72.8 bits (177), Expect = 1e-12
Identities = 112/554 (20%), Positives = 212/554 (38%), Gaps = 99/554 (17%)
Query: 218 EELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNIT 277
E+ +Y K K E + +N + W + E + I +AR YER + +
Sbjct: 8 EQAAEYVPEKVKKAEKKLEENPYDLDAWSILIR-EAQNQPIDKARKTYERLVAQFPSSGR 66
Query: 278 LWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWM 337
W Y E E+K + + ++ R + + ++ + +Y+ E G + ++ +
Sbjct: 67 FWKLYIEAEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKEKMAQAY 126
Query: 338 EWQPEE--------QAWHSYINF---------ELRYKEVDRARTIYERFVLVHPDV---K 377
++ ++ Q W YINF + + R +Y+R V+P + +
Sbjct: 127 DFALDKIGMEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVRRVYQR-GCVNPMINIEQ 185
Query: 378 NWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYK 437
W Y ++EE + + +R+ ++ + + + N
Sbjct: 186 LWRDYNKYEEGINIHLAKKMIEDRSRDYMNARRVAKEYETVMKGLDRNAPSVP------- 238
Query: 438 YALDRISKQDAQ--ELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWF 495
+ + Q+AQ +++K Y +EK R + +I + F YE+ + H+ D W+
Sbjct: 239 ---PQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPDIWY 295
Query: 496 DYLRLVESDAE--------------AEAVREVYERAIANVPPIQEKRHWKRYIYLWINYA 541
+ + +E ++ ++ +YERAI+ + K+ + L+ YA
Sbjct: 296 EAAQYLEQSSKLLAEKGDMNNAKLFSDEAANIYERAISTL--------LKKNMLLYFAYA 347
Query: 542 LYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIG 601
YEE K E+ +Y L+ + ++I Y +F ARRA G G
Sbjct: 348 DYEESRMK-YEKVHSIYN---RLLAIEDIDPTLVYIQYMKF---------ARRAEGIKSG 394
Query: 602 KCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARA 661
+ +FK + RE R R C+ D A
Sbjct: 395 R----MIFK-------KAREDTRTRHHVYVTAALMEYYCSK------------DKSVAFK 431
Query: 662 IYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQR-----TQHVKVWISFA 716
I+EL + + D+PE + +YID+ E TR L+ R+L + ++W F
Sbjct: 432 IFELGLKKYG-DIPEYV-LAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFL 489
Query: 717 QFELSSGKEGSLTK 730
FE + G S+ K
Sbjct: 490 AFESNIGDLASILK 503
Score = 55.8 bits (133), Expect = 2e-07
Identities = 89/419 (21%), Positives = 168/419 (40%), Gaps = 72/419 (17%)
Query: 163 AASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELND 222
A + A QRI V +V + I EQL R+ + E + ++ I E+ D
Sbjct: 155 AVGSYAENQRITAVRRVYQRGCVNPMINIEQLWRDYNKYEEGINIHLAKKMI--EDRSRD 212
Query: 223 YKLRKR--KTFE---------------DNIRKNRTVISNWIKYAQWEES--------LKE 257
Y +R K +E N + + W KY QWE+S
Sbjct: 213 YMNARRVAKEYETVMKGLDRNAPSVPPQNTPQEAQQVDMWKKYIQWEKSNPLRTEDQTLI 272
Query: 258 IQRARSIYERALDVDYRNITLWLKYAEM------------EMKNRQV--NHARNIWDRAI 303
+R YE+ L V + +W + A+ +M N ++ + A NI++RAI
Sbjct: 273 TKRVMFAYEQCLLVLGHHPDIWYEAAQYLEQSSKLLAEKGDMNNAKLFSDEAANIYERAI 332
Query: 304 TTLPRVNQ-FWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQ--AWHSYINFELRYKEVD 360
+TL + N ++ Y EE ++ R + + + + Y+ F R + +
Sbjct: 333 STLLKKNMLLYFAYADYEESRMKYEKVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIK 392
Query: 361 RARTIYERFVLVHPDVKN---------WIKYARFEEKHAYFAHARKVYERAVEFFGDEHM 411
R I+++ D + ++Y ++K F K++E ++ +GD +
Sbjct: 393 SGRMIFKK---AREDTRTRHHVYVTAALMEYYCSKDKSVAF----KIFELGLKKYGD--I 443
Query: 412 DEHLYVAFAKFEENQKEFERVRVIYKYAL--DRISKQDAQELFKNYTIFEKKFGDRRGIE 469
E++ +A+ + + E RV+++ L + + + E++ + FE GD I
Sbjct: 444 PEYV-LAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFESNIGDLASI- 501
Query: 470 DIIVSKRRF-----QYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPP 523
+ V KRRF +YE + A + + D S+ +A ++V +A + P
Sbjct: 502 -LKVEKRRFTAFKEEYEGKETALLVDRYKFMDLYPCSASELKALGYKDVSRAKLAAIIP 559
Score = 50.4 bits (119), Expect = 7e-06
Identities = 91/437 (20%), Positives = 172/437 (39%), Gaps = 102/437 (23%)
Query: 329 ARQVFERWMEWQPEE-QAWHSYINFELRYKEVDRARTIYERFVL--VHPDV-KNWIKYAR 384
AR+ +ER + P + W YI E++ K D+ +++R ++ +H D+ K ++ Y R
Sbjct: 50 ARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVR 109
Query: 385 FEEKH--AYFAHARKVYERAVEFFGDEHMDEHLYVAFAKF----------EENQKEFERV 432
+ +Y + Y+ A++ G E M ++V + F ENQ+
Sbjct: 110 ETKGKLPSYKEKMAQAYDFALDKIGMEIMSYQIWVDYINFLKGVEAVGSYAENQRITAVR 169
Query: 433 RVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYD 492
RV + ++ + + ++L+++Y +E+ GI +I ++K+ + D
Sbjct: 170 RVYQRGCVNPMI--NIEQLWRDYNKYEE------GI-NIHLAKKMIE------------D 208
Query: 493 AWFDYLRLVESDAEAEAVREVYERAIANVPP------IQEKRHWKRYIYLWINYALYEEL 546
DY+ E E V + +R +VPP Q+ WK+YI + L E
Sbjct: 209 RSRDYMNARRVAKEYETVMKGLDRNAPSVPPQNTPQEAQQVDMWKKYIQWEKSNPLRTED 268
Query: 547 EAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKN 606
+ +R Y+ L ++ H +W AQ+ + Q + LA + G
Sbjct: 269 QTLITKRVMFAYEQCLLVLGHHP----DIWYEAAQY-LEQSSKLLAEK------GDMNNA 317
Query: 607 KLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELA 666
KLF D A IYE A
Sbjct: 318 KLFS----------------------------------------------DEAANIYERA 331
Query: 667 ISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFELSSGKEG 726
IS L +L+ +Y D+E + + E+ ++Y RLL + + + + Q+ + +
Sbjct: 332 IST-LLKKNMLLYFAYADYEESRMKYEKVHSIYNRLL-AIEDIDPTLVYIQYMKFARRAE 389
Query: 727 SLTKCRQIYEEANKTMR 743
+ R I+++A + R
Sbjct: 390 GIKSGRMIFKKAREDTR 406
Score = 43.9 bits (102), Expect = 6e-04
Identities = 46/191 (24%), Positives = 81/191 (42%), Gaps = 29/191 (15%)
Query: 627 KLYEKFLEFGPENCTSW-IKFAELETILGDIDRARAIYELAISQPRLDMPEVLWKSYIDF 685
K EK LE P + +W I E + ID+AR YE ++Q WK YI+
Sbjct: 19 KKAEKKLEENPYDLDAWSILIREAQN--QPIDKARKTYERLVAQ--FPSSGRFWKLYIEA 74
Query: 686 EIEQEETERTRNLYRRLLQRTQHVKVWISFAQF------ELSSGKEGSLTKCRQIYEEAN 739
EI+ + ++ L++R L + H+ +W + + +L S KE K Q Y+ A
Sbjct: 75 EIKAKNYDKVEKLFQRCLMKVLHIDLWKCYLSYVRETKGKLPSYKE----KMAQAYDFA- 129
Query: 740 KTMRNCEEKEERLMLLESWRSF------EEEFGTASDKERVDKLMPEKVKKRRKVQTDDG 793
++ +M + W + E G+ ++ +R+ + +V +R V
Sbjct: 130 -----LDKIGMEIMSYQIWVDYINFLKGVEAVGSYAENQRITAV--RRVYQRGCVNPMIN 182
Query: 794 SDAGWEEYFDY 804
+ W +Y Y
Sbjct: 183 IEQLWRDYNKY 193
>gi|70980549 programmed cell death 11 [Homo sapiens]
Length = 1871
Score = 64.7 bits (156), Expect = 3e-10
Identities = 67/366 (18%), Positives = 147/366 (40%), Gaps = 47/366 (12%)
Query: 173 IPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFE 232
+PK + K +Q+++ + LPP + ++E+E K+ E
Sbjct: 1517 LPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKE 1576
Query: 233 DNIRKNRTVISNWIKYAQWEESLKEIQR---ARSIYERALDVDYRNITLWLKYAEMEMKN 289
+ K + + ++ EE+L + R + ++R + + LWL+Y ++
Sbjct: 1577 RELEKQKAEK----ELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQA 1632
Query: 290 RQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSY 349
++ AR + +RA+ T+ ++ EE Q + W +
Sbjct: 1633 TEIEKARAVAERALKTI----------SFREE------------------QEKLNVWVAL 1664
Query: 350 INFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDE 409
+N E Y + ++ER V + +K ++ A K F A ++Y R ++ F E
Sbjct: 1665 LNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQE 1724
Query: 410 HMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIE 469
+ +++ + F + + + + AL+ + ++ ++ + E + GD +
Sbjct: 1725 ---KAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK 1781
Query: 470 DIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAI-ANVPPIQEKR 528
I +E + P D W Y+ + + VR+++ER I ++ P + K
Sbjct: 1782 AI--------FENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKF 1833
Query: 529 HWKRYI 534
+KRY+
Sbjct: 1834 FFKRYL 1839
Score = 60.8 bits (146), Expect = 5e-09
Identities = 72/353 (20%), Positives = 143/353 (40%), Gaps = 53/353 (15%)
Query: 162 MAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELN 221
+A S+ + + P A +K K+ E ++ ++ +E E L+ P Q + D+
Sbjct: 1553 LAESSDSEEDEKPHQATIK-KSKKERELEKQKAEKELSRIEEALMDPGRQPESADD---- 1607
Query: 222 DYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLK 281
F+ + + W++Y + EI++AR++ ERAL
Sbjct: 1608 ---------FDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKT---------- 1648
Query: 282 YAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQP 341
+ R+ N+W + +E M G+ +VFER +++
Sbjct: 1649 -----ISFREEQEKLNVWVALLN--------------LENMYGSQESLTKVFERAVQYNE 1689
Query: 342 EEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKN-WIKYARFEEKHAYFAHARKVYE 400
+ + + + ++ A +Y R + K WIKY F + + A + +V +
Sbjct: 1690 PLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQ 1749
Query: 401 RAVEFF-GDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQ-DAQELFKNYTIF 458
RA+E EH+D + FA+ E + ER + I++ L K+ D ++ + TI
Sbjct: 1750 RALECLPSKEHVD--VIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTI- 1806
Query: 459 EKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVR 511
K G ++ + DI +R K + + DY + ++ + +AV+
Sbjct: 1807 --KHGSQKDVRDIF--ERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVK 1855
Score = 54.3 bits (129), Expect = 5e-07
Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 8/184 (4%)
Query: 229 KTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMK 288
K FE ++ N + ++ A ++ Q A +Y R L + +W+KY ++
Sbjct: 1679 KVFERAVQYNEP-LKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLR 1737
Query: 289 NRQVNHARNIWDRAITTLPRVN--QFWYKYTYMEEMLGNVAGARQVFERWMEWQPEE-QA 345
Q + + RA+ LP K+ +E LG+ A+ +FE + P+
Sbjct: 1738 RSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDV 1797
Query: 346 WHSYINFELRYKEVDRARTIYERFV---LVHPDVKNWIK-YARFEEKHAYFAHARKVYER 401
W YI+ +++ R I+ER + L +K + K Y +E++H + V +
Sbjct: 1798 WSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAK 1857
Query: 402 AVEF 405
A+E+
Sbjct: 1858 ALEY 1861
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/231 (25%), Positives = 99/231 (42%), Gaps = 23/231 (9%)
Query: 480 YEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRH---WKRYIYL 536
++ V ++P++ W Y+ E E R V ERA+ + +E+ W + L
Sbjct: 1608 FDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNL 1667
Query: 537 WINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRAL 596
Y E L K ER Q Y L++ H +AK E+ + L R+
Sbjct: 1668 ENMYGSQESL-TKVFERAVQ-YNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQ-- 1723
Query: 597 GTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGP--ENCTSWIKFAELETILG 654
+ ++ Y L+ + ++ ++ LE P E+ KFA+LE LG
Sbjct: 1724 --------EKAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLG 1775
Query: 655 DIDRARAIYELAIS--QPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLL 703
D +RA+AI+E +S R D +W YID I+ + R+++ R++
Sbjct: 1776 DAERAKAIFENTLSTYPKRTD----VWSVYIDMTIKHGSQKDVRDIFERVI 1822
Score = 35.8 bits (81), Expect = 0.17
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 12/80 (15%)
Query: 665 LAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLL------QRTQHVKVWISFAQF 718
L +S P +LW Y+ F ++ E E+ R + R L + + + VW++
Sbjct: 1611 LVLSSPN---SSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNL 1667
Query: 719 ELSSGKEGSLTKCRQIYEEA 738
E G + SLTK ++E A
Sbjct: 1668 ENMYGSQESLTK---VFERA 1684
>gi|169172639 PREDICTED: similar to U5 snRNP-associated 102 kDa
protein [Homo sapiens]
Length = 406
Score = 61.2 bits (147), Expect = 4e-09
Identities = 68/321 (21%), Positives = 122/321 (38%), Gaps = 27/321 (8%)
Query: 258 IQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYT 317
++ AR+IY AL V ++WL+ A E + + RA+ P+ W
Sbjct: 21 LECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGA 80
Query: 318 YMEEMLGNVAGARQVFERWMEWQP-EEQAWHSYINFELRYKEVDRARTIYERFVLVHPDV 376
+ + G+V AR + + P E+ W + + E E +RAR + + P
Sbjct: 81 KSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTA 140
Query: 377 KNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIY 436
+ ++K + E A+ + E A+ + D L++ + EE ++ E+ R Y
Sbjct: 141 RVFMKSVKLEWVQDNIRAAQDLCEEALRHYED---FPKLWMMKGQIEEQKEMMEKAREAY 197
Query: 437 KYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFD 496
L + + L+ + E+K G +++ R E+ NP N W +
Sbjct: 198 NQGLKKC--PHSTPLWLLLSRLEEKIGQ--------LTRARAILEKSRLKNPKNPGLWLE 247
Query: 497 YLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQ 556
+RL + +A+ P W I+ LEA+ RT+
Sbjct: 248 SVRLEYRAGLKNIANTLMAKALQECP--NSGILWSEAIF----------LEARPQRRTKS 295
Query: 557 V-YQASLELIPHKKFTFAKMW 576
V E PH AK++
Sbjct: 296 VDALKKCEHDPHVLLAVAKLF 316
Score = 46.6 bits (109), Expect = 1e-04
Identities = 35/160 (21%), Positives = 72/160 (45%), Gaps = 3/160 (1%)
Query: 245 WIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAIT 304
W+ A+ + ++ ARSI A + + +WL ++E +N + AR + +A +
Sbjct: 76 WLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARS 135
Query: 305 TLPRVNQFWYKYTYMEEMLGNVAGARQVFERWM-EWQPEEQAWHSYINFELRYKEVDRAR 363
+ P F K +E + N+ A+ + E + ++ + W E + + +++AR
Sbjct: 136 SAPTARVF-MKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAR 194
Query: 364 TIYERFVLVHP-DVKNWIKYARFEEKHAYFAHARKVYERA 402
Y + + P W+ +R EEK AR + E++
Sbjct: 195 EAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKS 234
Score = 45.8 bits (107), Expect = 2e-04
Identities = 43/214 (20%), Positives = 89/214 (41%), Gaps = 5/214 (2%)
Query: 189 ITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKY 248
I A Q L E R E P K EE+ + + R+ + ++K W+
Sbjct: 156 IRAAQDLCEEALRHYEDFPKLWMMKGQIEEQ-KEMMEKAREAYNQGLKKCPHSTPLWLLL 214
Query: 249 AQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPR 308
++ EE + ++ RAR+I E++ + +N LWL+ +E + N A + +A+ P
Sbjct: 215 SRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPN 274
Query: 309 VNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYER 368
W + ++E + + + + + + +++ +AR + R
Sbjct: 275 SGILWSEAIFLE---ARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHR 331
Query: 369 FVLVHPDVKN-WIKYARFEEKHAYFAHARKVYER 401
V + D+ + W + +FE +H +V +R
Sbjct: 332 TVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKR 365
Score = 44.7 bits (104), Expect = 4e-04
Identities = 69/291 (23%), Positives = 109/291 (37%), Gaps = 30/291 (10%)
Query: 430 ERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPH 489
E R IY YAL + + L Y FEK G R +E ++ + V P
Sbjct: 22 ECARAIYAYALQVFPSKKSVWLRAAY--FEKNHGTRESLEALL--------QRAVAHCPK 71
Query: 490 NYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAK 549
W + + A R + A P +E +W+ A+ E E
Sbjct: 72 AEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEE---------IWLA-AVKLESEND 121
Query: 550 DPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLF 609
+ ER R++ + P + + + + Q IR L AL PK +
Sbjct: 122 EYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQ-DLCEEAL-RHYEDFPKLWMM 179
Query: 610 KVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQ 669
K IE + ++ E + R+ Y + L+ P + W+ + LE +G + RARAI E +
Sbjct: 180 KGQIEEQKEMME--KAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILE----K 233
Query: 670 PRLDMPE--VLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQF 718
RL P+ LW + E L + LQ + + S A F
Sbjct: 234 SRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIF 284
Score = 40.4 bits (93), Expect = 0.007
Identities = 38/194 (19%), Positives = 77/194 (39%), Gaps = 4/194 (2%)
Query: 243 SNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRA 302
S W++ A +E++ + ++ +RA+ + LWL A+ + V AR+I A
Sbjct: 40 SVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALA 99
Query: 303 ITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRA 362
P + W +E AR++ + P + + + E + A
Sbjct: 100 FQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAA 159
Query: 363 RTIYERFVLVHPDV-KNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAK 421
+ + E + + D K W+ + EE+ AR+ Y + ++ L++ ++
Sbjct: 160 QDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPH---STPLWLLLSR 216
Query: 422 FEENQKEFERVRVI 435
EE + R R I
Sbjct: 217 LEEKIGQLTRARAI 230
>gi|49574529 hepatocellular carcinoma-associated antigen 66 [Homo
sapiens]
Length = 597
Score = 60.1 bits (144), Expect = 9e-09
Identities = 105/537 (19%), Positives = 209/537 (38%), Gaps = 57/537 (10%)
Query: 225 LRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAE 284
++K E I++ ++I Y Q+E +L E+ + R + + +
Sbjct: 34 IKKASDLEYKIQRRTLFKEDFINYVQYEINLLEL------------IQRRRTRIGYSFKK 81
Query: 285 MEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQ 344
E++N V+ + ++ RA Q W Y + +VF + +
Sbjct: 82 DEIENSIVHRVQGVFQRASAKWKDDVQLWLSYVAFCKKWATKTRLSKVFSAMLAIHSNKP 141
Query: 345 A-WHSYINFELRYK-EVDRARTIYERFVLVHPDV-KNWIKYARFEEKHAYFAHARKVYER 401
A W +E+ + + AR ++ R + HP+ K + +Y R E HA K
Sbjct: 142 ALWIMAAKWEMEDRLSSESARQLFLRALRFHPECPKLYKEYFRMELMHAEKLRKEK---- 197
Query: 402 AVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALD-------RISKQDAQELFKN 454
E F MD V + E + E +IYK ++ +S +LF
Sbjct: 198 --EEFEKASMD----VENPDYSEEILKGELAWIIYKNSVSIIKGAEFHVSLLSIAQLFDF 251
Query: 455 YTIFEKK-FGDRRGI--EDII----VSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEA 507
+K+ + D + + +D + V++R + E + + P A + VE +
Sbjct: 252 AKDLQKEIYDDLQALHTDDPLTWDYVARRELEIESQTEEQPTTKQA-----KAVEVGRKE 306
Query: 508 EAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEE----LEAKDPERTRQVYQASLE 563
E VYE A+ +P + WK YI + + L K ERT V++ + E
Sbjct: 307 ERCCAVYEEAVKTLP---TEAMWKCYITFCLERFTKKSNSGFLRGKRLERTMTVFRKAHE 363
Query: 564 LIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFD 623
L + + ++ + + ++ L +A GT + + ++++ +++ ++ + D
Sbjct: 364 LKLLSECQYKQLSVSLLCYNFLREALEVA--VAGTELFR-DSGTMWQLKLQVLIESKSPD 420
Query: 624 RCRKLYEKFLEFGPENCTS-WIKFAELETILGDIDRARAIYELAISQPRLDMPEVLWKSY 682
E F+ P+ C WI +AE + A+++ A+ L Y
Sbjct: 421 IAMLFEEAFVHLKPQVCLPLWISWAEWSEGAKSQEDTEAVFKKALLAVIGADSVTLKNKY 480
Query: 683 IDFEIEQEETERTRNLYRRLLQ-RTQHVKVWISFAQFELSSGKEGSLTKCRQIYEEA 738
+D+ ++ R +++ L + R V + QFE + ++ R+ YE A
Sbjct: 481 LDWAYRSGGYKKARAVFKSLQESRPFSVDFFRKMIQFE-KEQESCNMANIREYYERA 536
Score = 38.9 bits (89), Expect = 0.020
Identities = 28/126 (22%), Positives = 56/126 (44%), Gaps = 6/126 (4%)
Query: 237 KNRTVISNWIKYAQWEESLKEIQRARSIYERAL--DVDYRNITLWLKYAEMEMKNRQVNH 294
K + + WI +A+W E K + +++++AL + ++TL KY + ++
Sbjct: 433 KPQVCLPLWISWAEWSEGAKSQEDTEAVFKKALLAVIGADSVTLKNKYLDWAYRSGGYKK 492
Query: 295 ARNIWDRAITTLPRVNQFWYKYTYM--EEMLGNVAGARQVFERWME--WQPEEQAWHSYI 350
AR ++ + P F+ K E+ N+A R+ +ER + + W Y+
Sbjct: 493 ARAVFKSLQESRPFSVDFFRKMIQFEKEQESCNMANIREYYERALREFGSADSDLWMDYM 552
Query: 351 NFELRY 356
EL +
Sbjct: 553 KEELNH 558
Score = 32.3 bits (72), Expect = 1.9
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 217 EEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNI 276
+E N R + F+ K + + W+ Y + + R ++ L +
Sbjct: 82 DEIENSIVHRVQGVFQRASAKWKDDVQLWLSYVAFCKKWATKTRLSKVFSAMLAIHSNKP 141
Query: 277 TLWLKYAEMEMKNR-QVNHARNIWDRAITTLPRVNQFWYKYTYMEEM 322
LW+ A+ EM++R AR ++ RA+ P + + +Y ME M
Sbjct: 142 ALWIMAAKWEMEDRLSSESARQLFLRALRFHPECPKLYKEYFRMELM 188
>gi|7661952 squamous cell carcinoma antigen recognized by T cells 3
[Homo sapiens]
Length = 963
Score = 52.4 bits (124), Expect = 2e-06
Identities = 80/388 (20%), Positives = 157/388 (40%), Gaps = 61/388 (15%)
Query: 481 EEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINY 540
EE++ N ++Y+ D +RL+ + E VR ++ ++ + P+ E+ LW+ +
Sbjct: 102 EEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQK-MSEIFPLTEE--------LWLEW 152
Query: 541 ALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEI--------RQKNLSLA 592
E A+D VY + + K + +W+ Y Q+ + +K S+
Sbjct: 153 LHDEISMAQDGLDREHVYDLFEKAV--KDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVF 210
Query: 593 RRALGT-SIGKCPKNKLFKVYIELELQLREFDRCRKLYEKF----------LEFGPENCT 641
RAL + + L++ Y E E + E R K++ F +E
Sbjct: 211 ERALSSVGLHMTKGLALWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYE 270
Query: 642 SWIKFAELETILGDIDRA------RAIYELAISQ---PRLDMPEVLWKSYIDFEIEQEET 692
W + E+++ + ++A YE A+ Q PRL +++YIDFE++ +
Sbjct: 271 EWSEDPIPESVIQNYNKALQQLEKYKPYEEALLQAEAPRL----AEYQAYIDFEMKIGDP 326
Query: 693 ERTRNLYRR-LLQRTQHVKVWISFAQFELSSGKEGSLTKCRQIYEEANKTMRNCEEKEER 751
R + ++ R L++ +WI ++Q+ K L + N+ +RNC
Sbjct: 327 ARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDL-----VLSVHNRAIRNCP----- 376
Query: 752 LMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYI-----F 806
+ W + +V + EK +Q D + W+ Y DY+ F
Sbjct: 377 -WTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEI-WQAYLDYLRRRVDF 434
Query: 807 PEDAANQPNLKLLAMAKLWKKQQQEKED 834
+D++ + A + + +QE E+
Sbjct: 435 KQDSSKELEELRAAFTRALEYLKQEVEE 462
Score = 41.6 bits (96), Expect = 0.003
Identities = 68/364 (18%), Positives = 145/364 (39%), Gaps = 104/364 (28%)
Query: 245 WIKYAQWEES----LKEIQRARSIYERALDVDYRNIT----LWLKYAEME---MKNRQVN 293
W++Y Q+ +++ RS++ERAL ++T LW Y E E ++ ++
Sbjct: 186 WLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLALWEAYREFESAIVEAARLE 245
Query: 294 HARNIWDRAITTLPRVN--------QFWYKYTYMEEMLGNVAGARQVFERWMEWQ----- 340
+++ R + +P + + W + E ++ N A Q E++ ++
Sbjct: 246 KVHSLFRRQLA-IPLYDMEATFAEYEEWSEDPIPESVIQNYNKALQQLEKYKPYEEALLQ 304
Query: 341 ---PEEQAWHSYINFELRYKEVDRARTIYERFVLVH---PDVKNWIKYARFEEKH----- 389
P + +YI+FE++ + R + I+ER ++ + PD+ WI+Y+++ ++
Sbjct: 305 AEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDL--WIRYSQYLDRQLKVKD 362
Query: 390 -AYFAHARKV------------YERAVEFFGDEHM------DEHLYVAFAKF-------- 422
H R + Y A+E G +H ++ L F +
Sbjct: 363 LVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIWQ 422
Query: 423 -------------EENQKEFERVRVIYKYALDRISKQDAQELF-----------KNYTIF 458
+++ KE E +R + AL+ + KQ+ +E F +N+
Sbjct: 423 AYLDYLRRRVDFKQDSSKELEELRAAFTRALEYL-KQEVEERFNESGDPSCVIMQNWARI 481
Query: 459 EKKFGDR----RGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVY 514
E + + R + D I+++ +Y + W +Y L + + + R+
Sbjct: 482 EARLCNNMQKARELWDSIMTRGNAKYA----------NMWLEYYNLERAHGDTQHCRKAL 531
Query: 515 ERAI 518
RA+
Sbjct: 532 HRAV 535
Score = 35.0 bits (79), Expect = 0.29
Identities = 51/293 (17%), Positives = 107/293 (36%), Gaps = 67/293 (22%)
Query: 224 KLRKRKTFEDNIRKNRTV-ISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKY 282
+L K K +E+ + + ++ + Y +E + + R + I+ERAL + LW++Y
Sbjct: 291 QLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRY 350
Query: 283 AE-MEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLG------NVAGARQVFER 335
++ ++ + + + ++ +RAI P W +Y E G +V + +
Sbjct: 351 SQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTFEKALNAG 410
Query: 336 WMEWQPEEQAWHSYINFELR--------YKEVDRARTIY------------ERF------ 369
+++ + W +Y+++ R KE++ R + ERF
Sbjct: 411 FIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYLKQEVEERFNESGDP 470
Query: 370 ----------------------------VLVHPDVK---NWIKYARFEEKHAYFAHARKV 398
++ + K W++Y E H H RK
Sbjct: 471 SCVIMQNWARIEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKA 530
Query: 399 YERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQEL 451
RAV+ D EH+ E + E + + R+++ + Q +
Sbjct: 531 LHRAVQCTSD--YPEHVCEVLLTMERTEGSLEDWDIAVQKTETRLARVNEQRM 581
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 49.7 bits (117), Expect = 1e-05
Identities = 82/424 (19%), Positives = 163/424 (38%), Gaps = 53/424 (12%)
Query: 276 ITLWLKYAEMEMKNRQVNHAR-NIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFE 334
+ L L ++ +K ++ +R +++ + TLP + Y Y + G A +
Sbjct: 340 VLLLLLFSWKTVKQNEIWLSRESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYR 399
Query: 335 RWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAH 394
++ P + + N ++ A+ Y+R + +HP A F + +
Sbjct: 400 TALKLYPRHAS--ALNNLGTLTRDTAEAKMYYQRALQLHPQHNR----ALFNLGNLLKSQ 453
Query: 395 ARKVYERAVEF------FGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDA 448
+K E A+ +G E D Y + A Q+ F+ IY+ + D+
Sbjct: 454 EKK--EEAITLLKDSIKYGPEFADA--YSSLASLLAEQERFKEAEEIYQTGIKNCP--DS 507
Query: 449 QELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAE 508
+L NY +F G + K Y++ +K +P ++ A + RL S E
Sbjct: 508 SDLHNNYGVFLVDTG--------LPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENS 559
Query: 509 AVREVYERAIANVPPIQEKRHWKRYIYLWINY----ALYEELEAKDPE------------ 552
E Y+RA+ + Y Y +Y+E A P
Sbjct: 560 MAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVL 619
Query: 553 ----RTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNK- 607
+T++ + + ++ + +L A + +Q+N A A+ ++ PK+
Sbjct: 620 AVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYS-KQENHDKALDAIDKALQLKPKDPK 678
Query: 608 -LFKVYIELELQLREFDRCRKLYEKF---LEFGPENCTSWIKFAELETILGDIDRARAIY 663
+ +++ QLRE + K +E + ++ P+ +W+ ++ I G ARA Y
Sbjct: 679 VISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYY 738
Query: 664 ELAI 667
E A+
Sbjct: 739 ERAL 742
Score = 30.8 bits (68), Expect = 5.5
Identities = 32/189 (16%), Positives = 68/189 (35%), Gaps = 14/189 (7%)
Query: 481 EEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINY 540
++ +K P DA+ L+ + E+Y+ I N P + L NY
Sbjct: 464 KDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSD---------LHNNY 514
Query: 541 ALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSI 600
++ ++ PE+ YQ +++L P + LY +RAL +
Sbjct: 515 GVF-LVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVA- 572
Query: 601 GKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRAR 660
K ++ L ++ ++Y++ P + A++ ++G A
Sbjct: 573 ---HKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAE 629
Query: 661 AIYELAISQ 669
+ +S+
Sbjct: 630 KMTNHIVSE 638
>gi|156938331 PRP39 pre-mRNA processing factor 39 homolog [Homo
sapiens]
Length = 669
Score = 44.3 bits (103), Expect = 5e-04
Identities = 95/486 (19%), Positives = 177/486 (36%), Gaps = 99/486 (20%)
Query: 272 DYRNITLWLKYAEMEMKNRQVNH---ARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAG 328
D+ L+Y E E NH AR +DR P +W KY +E+ N+
Sbjct: 94 DFTGWVYLLQYVEQE------NHLMAARKAFDRFFIHYPYCYGYWKKYADLEKRHDNIKP 147
Query: 329 ARQVFERWMEWQP-EEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEE 387
+ +V+ R ++ P W YINF + E P+ N I
Sbjct: 148 SDEVYRRGLQAIPLSVDLWIHYINF------------LKETLDPGDPETNNTI------- 188
Query: 388 KHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQD 447
R +E AV G + + L+ + +E Q V IY DRI
Sbjct: 189 --------RGTFEHAVLAAGTDFRSDRLWEMYINWENEQGNLREVTAIY----DRILGIP 236
Query: 448 AQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEV-KANPHNYDAWFDYLRLVESDAE 506
Q L+ ++ K+ D++ ++ Q E+ N H+ D D
Sbjct: 237 TQ-LYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELASVNGHSGDDG------PPGDDL 289
Query: 507 AEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIP 566
+ ++ + A + I+ RH R +++Q E+
Sbjct: 290 PSGIEDITDPA-KLITEIENMRH-----------------------RIIEIHQ---EMFN 322
Query: 567 HKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCR 626
+ + +K W + ++ +A + K +K Y+E E++ +R
Sbjct: 323 YNEHEVSKRWTFEEGIKRPYFHVKPLEKA---------QLKNWKEYLEFEIENGTHERVV 373
Query: 627 KLYEKFLEFGPENCTSWIKFAE-LETILGDIDRARAIYELA--ISQPRLDMPEVLWKSYI 683
L+E+ + WIK+A+ +E I+ R ++ A I P+ M +LW ++
Sbjct: 374 VLFERCVISCALYEEFWIKYAKYMEN--HSIEGVRHVFSRACTIHLPKKPMVHMLWAAF- 430
Query: 684 DFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFELSS--GKEGSLTKCRQIYEEANKT 741
EE + N R +L+ + + ++ + S + G+L + + ++A K
Sbjct: 431 ------EEQQGNINEARNILKTFEECVLGLAMVRLRRVSLERRHGNLEEAEHLLQDAIKN 484
Query: 742 MRNCEE 747
++ E
Sbjct: 485 AKSNNE 490
Score = 41.2 bits (95), Expect = 0.004
Identities = 55/261 (21%), Positives = 106/261 (40%), Gaps = 40/261 (15%)
Query: 221 NDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWL 280
N++++ KR TFE+ I++ Y ++ + W
Sbjct: 324 NEHEVSKRWTFEEGIKRP--------------------------YFHVKPLEKAQLKNWK 357
Query: 281 KYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYT-YMEEMLGNVAGARQVFERWMEW 339
+Y E E++N +++R + + +FW KY YME ++ G R VF R
Sbjct: 358 EYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMEN--HSIEGVRHVFSRACTI 415
Query: 340 Q-PEEQAWHS-YINFELRYKEVDRARTI---YERFVLVHPDVKNWIKYARFEEKHAYFAH 394
P++ H + FE + ++ AR I +E VL V+ ++ E +H
Sbjct: 416 HLPKKPMVHMLWAAFEEQQGNINEARNILKTFEECVLGLAMVR--LRRVSLERRHGNLEE 473
Query: 395 ARKVYERAVEFFGDEHMDEHLYVAFAK-FEENQKEFERVRVIYKYALDRISKQDAQELFK 453
A + + A++ + V A+ + QK + R + A++R ++ +L+
Sbjct: 474 AEHLLQDAIKNAKSNNESSFYAVKLARHLFKIQKNLPKSRKVLLEAIER--DKENTKLYL 531
Query: 454 NYTIFEKKFGDRRGIEDIIVS 474
N E GD + E+ I++
Sbjct: 532 NLLEMEYS-GDLKQNEENILN 551
Score = 38.5 bits (88), Expect = 0.027
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 10/105 (9%)
Query: 679 WKSYIDFEIEQEETERTRNLYRR-LLQRTQHVKVWISFAQFELSSGKEGSLTKCRQIYEE 737
WK Y++FEIE ER L+ R ++ + + WI +A++ + EG R ++
Sbjct: 356 WKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHSIEG----VRHVFSR 411
Query: 738 ANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKV 782
A ++ M+ W +FEE+ G ++ + K E V
Sbjct: 412 ACTI-----HLPKKPMVHMLWAAFEEQQGNINEARNILKTFEECV 451
Score = 35.0 bits (79), Expect = 0.29
Identities = 89/463 (19%), Positives = 168/463 (36%), Gaps = 62/463 (13%)
Query: 219 ELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITL 278
E ++ + RK F+ W KYA E+ I+ + +Y R L ++ L
Sbjct: 106 EQENHLMAARKAFDRFFIHYPYCYGYWKKYADLEKRHDNIKPSDEVYRRGLQAIPLSVDL 165
Query: 279 WLKYAE-----MEMKNRQVNHA-RNIWDRAIT---TLPRVNQFWYKYTYMEEMLGNVAGA 329
W+ Y ++ + + N+ R ++ A+ T R ++ W Y E GN+
Sbjct: 166 WIHYINFLKETLDPGDPETNNTIRGTFEHAVLAAGTDFRSDRLWEMYINWENEQGNLREV 225
Query: 330 RQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYA------ 383
+++R + + + H E + R E+F+ + ++ + ++
Sbjct: 226 TAIYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELASVNGHSGDDGPP 285
Query: 384 ---------RFEEKHAYFAHARKVYERAVEFFGDE-HMDEHLYVAFAKFEEN-QKEFERV 432
+ + R +E + + +EH FEE ++ + V
Sbjct: 286 GDDLPSGIEDITDPAKLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRPYFHV 345
Query: 433 RVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYD 492
+ + K L +K Y FE + G E ++V +E V + +
Sbjct: 346 KPLEKAQLKN---------WKEYLEFEIENGTH---ERVVV-----LFERCVISCALYEE 388
Query: 493 AWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPE 552
W Y + +E+ + E VR V+ RA P + H LW A +EE + E
Sbjct: 389 FWIKYAKYMENHS-IEGVRHVFSRACTIHLPKKPMVH-----MLW---AAFEEQQGNINE 439
Query: 553 RTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVY 612
R + + E + A + + E R NL A L +I N Y
Sbjct: 440 -ARNILKTFEECV----LGLAMVRLRRVSLERRHGNLEEAEHLLQDAIKNAKSNNESSFY 494
Query: 613 -IELELQL----REFDRCRKLYEKFLEFGPENCTSWIKFAELE 650
++L L + + RK+ + +E EN ++ E+E
Sbjct: 495 AVKLARHLFKIQKNLPKSRKVLLEAIERDKENTKLYLNLLEME 537
Score = 32.0 bits (71), Expect = 2.5
Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 8/95 (8%)
Query: 629 YEKF---LEFGPENCTSWIKFAELETILGDIDRARAIYE-LAISQPRLDMPEVLWKSYID 684
YEKF +E P++ T W+ + + AR ++ I P WK Y D
Sbjct: 81 YEKFWKTVENNPQDFTGWVYLLQYVEQENHLMAARKAFDRFFIHYPYC---YGYWKKYAD 137
Query: 685 FEIEQEETERTRNLYRRLLQRTQ-HVKVWISFAQF 718
E + + + +YRR LQ V +WI + F
Sbjct: 138 LEKRHDNIKPSDEVYRRGLQAIPLSVDLWIHYINF 172
>gi|42476022 tetratricopeptide repeat domain 27 [Homo sapiens]
Length = 843
Score = 41.2 bits (95), Expect = 0.004
Identities = 31/153 (20%), Positives = 67/153 (43%), Gaps = 3/153 (1%)
Query: 255 LKEIQRARSIYERALDVD-YRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFW 313
L ++ S Y++A ++ YR+ A + ++N++ ++R++ P W
Sbjct: 505 LGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVW 564
Query: 314 YKYTYMEEMLGNVAGARQVFERWMEWQPEE-QAWHSYINFELRYKEVDRA-RTIYERFVL 371
+ L + G+ + F+R + +P+ +AW++ +R K+ +A RT+ E
Sbjct: 565 FSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKC 624
Query: 372 VHPDVKNWIKYARFEEKHAYFAHARKVYERAVE 404
+ + W Y F+ A K Y R ++
Sbjct: 625 NYEHWQIWENYILTSTDVGEFSEAIKAYHRLLD 657
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 37.7 bits (86), Expect = 0.045
Identities = 77/388 (19%), Positives = 155/388 (39%), Gaps = 46/388 (11%)
Query: 413 EHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDII 472
E + A A ++ Q+ F++V +K LD + ++ ++ + F R E+++
Sbjct: 1437 ERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVV 1496
Query: 473 VSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKR 532
+ E + D ++ EAE +++ E QEK
Sbjct: 1497 DQLETLRRENK-NLQEEISDLTEQIAETGKNLQEAEKTKKLVE---------QEKSD--- 1543
Query: 533 YIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLA 592
+ AL EE+E ++ + LEL K K+ + E ++N A
Sbjct: 1544 -----LQVAL-EEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRA 1597
Query: 593 RRALGTSIGK--CPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELE 650
AL + + +N ++ ++E L E + ++ G N L
Sbjct: 1598 AEALQSVLDAEIRSRNDALRLKKKMEGDLNEME---------IQLGHSNRQMAETQKHLR 1648
Query: 651 TILGDIDRARAIYELAISQPRLDMPE----------VLWKSYIDFEIEQEETERTRNLYR 700
T+ G + ++ + A+ D+ E +L + + ++ E+TERTR L
Sbjct: 1649 TVQGQLKDSQLHLDDALRSNE-DLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSE 1707
Query: 701 R-LLQRTQHVKVWISFAQFELSSGK--EGSLTKCRQIYEEANKTMRNCEEKEERLMLLES 757
+ LL + V++ S +++ K E + +C+ E + + RN EEK ++ + +
Sbjct: 1708 QELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAA 1767
Query: 758 WRSFE--EEFGTASDKERVDKLMPEKVK 783
+ E +E T++ ER+ K + + VK
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNLEQTVK 1795
>gi|39932581 hypothetical protein LOC55051 isoform 2 [Homo sapiens]
Length = 933
Score = 37.7 bits (86), Expect = 0.045
Identities = 73/422 (17%), Positives = 154/422 (36%), Gaps = 79/422 (18%)
Query: 336 WMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKN----WIKYARFEEKHAY 391
W++++ + W + + R K + + +L P+ N W +YA E
Sbjct: 505 WLQYEIAKVIWCLHTKNKKRLKSQGKNCKKLAKNLLKEPENCNNFCLWKQYAHLEWLLGN 564
Query: 392 FAHARKVYERAVEFFGDEHMDE----HLYVAFAKFEENQKEFERVRVIYKYALDRISKQD 447
ARKV++ A+ G + + L + +A+ E R R A+ ++K
Sbjct: 565 TEDARKVFDTALGMAGSRELKDSDLCELSLLYAELEVELSPEVR-RAATARAVHILTKLT 623
Query: 448 AQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVK--------ANPHNYDAWFDYLR 499
+ YT + + + K R YE ++ +NP D+ +
Sbjct: 624 ESSPYGPYT---------GQVLAVHILKARKAYEHALQDCLGDSCVSNPAPTDSCSRLIS 674
Query: 500 LVES-------DAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPE 552
L + +A ++YE+ A +N +++ E +
Sbjct: 675 LAKCFMLFQYLTIGIDAAVQIYEQVFAK-----------------LNSSVFPEGSGEGDS 717
Query: 553 RTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNK-LFKV 611
+ Q + + LE I T +L ++ L+ R AL ++ P N+ L++
Sbjct: 718 ASSQSWTSVLEAI-----TLMHTSLLRFHMKVSVYPLAPLREALSQALKLYPGNQVLWRS 772
Query: 612 YIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETI------------------- 652
Y++++ + + R+ ++ + W+ E E +
Sbjct: 773 YVQIQNKSHSASKTRRFFDTITR-SAKPLEPWLFAIEAEKLRKRLVETVQRLDGREIHAT 831
Query: 653 ---LGDIDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHV 709
G + R +A++E A+ +LW+ Y++F + ER++ ++ + LQ
Sbjct: 832 IPETGLMHRIQALFENAMRSDSGSQCPLLWRMYLNFLVSLGNKERSKGVFYKALQNCPWA 891
Query: 710 KV 711
KV
Sbjct: 892 KV 893
>gi|39932583 hypothetical protein LOC55051 isoform 1 [Homo sapiens]
Length = 1164
Score = 37.7 bits (86), Expect = 0.045
Identities = 73/422 (17%), Positives = 154/422 (36%), Gaps = 79/422 (18%)
Query: 336 WMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKN----WIKYARFEEKHAY 391
W++++ + W + + R K + + +L P+ N W +YA E
Sbjct: 736 WLQYEIAKVIWCLHTKNKKRLKSQGKNCKKLAKNLLKEPENCNNFCLWKQYAHLEWLLGN 795
Query: 392 FAHARKVYERAVEFFGDEHMDE----HLYVAFAKFEENQKEFERVRVIYKYALDRISKQD 447
ARKV++ A+ G + + L + +A+ E R R A+ ++K
Sbjct: 796 TEDARKVFDTALGMAGSRELKDSDLCELSLLYAELEVELSPEVR-RAATARAVHILTKLT 854
Query: 448 AQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVK--------ANPHNYDAWFDYLR 499
+ YT + + + K R YE ++ +NP D+ +
Sbjct: 855 ESSPYGPYT---------GQVLAVHILKARKAYEHALQDCLGDSCVSNPAPTDSCSRLIS 905
Query: 500 LVES-------DAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPE 552
L + +A ++YE+ A +N +++ E +
Sbjct: 906 LAKCFMLFQYLTIGIDAAVQIYEQVFAK-----------------LNSSVFPEGSGEGDS 948
Query: 553 RTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNK-LFKV 611
+ Q + + LE I T +L ++ L+ R AL ++ P N+ L++
Sbjct: 949 ASSQSWTSVLEAI-----TLMHTSLLRFHMKVSVYPLAPLREALSQALKLYPGNQVLWRS 1003
Query: 612 YIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETI------------------- 652
Y++++ + + R+ ++ + W+ E E +
Sbjct: 1004 YVQIQNKSHSASKTRRFFDTITR-SAKPLEPWLFAIEAEKLRKRLVETVQRLDGREIHAT 1062
Query: 653 ---LGDIDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHV 709
G + R +A++E A+ +LW+ Y++F + ER++ ++ + LQ
Sbjct: 1063 IPETGLMHRIQALFENAMRSDSGSQCPLLWRMYLNFLVSLGNKERSKGVFYKALQNCPWA 1122
Query: 710 KV 711
KV
Sbjct: 1123 KV 1124
>gi|75709187 cleavage stimulation factor subunit 3 isoform 2 [Homo
sapiens]
Length = 103
Score = 36.6 bits (83), Expect = 0.10
Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 481 EEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINY 540
E++++ NP++ DAW +R ++ + R+ YER +A P R WK YI +
Sbjct: 22 EKKLEENPYDLDAWSILIREAQNQ-PIDKARKTYERLVAQFP--SSGRFWKLYIEAEVTI 78
Query: 541 ALY 543
Y
Sbjct: 79 LFY 81
>gi|96975038 coiled-coil domain containing 100 [Homo sapiens]
Length = 986
Score = 36.2 bits (82), Expect = 0.13
Identities = 58/263 (22%), Positives = 121/263 (46%), Gaps = 22/263 (8%)
Query: 584 IRQKNLSLARRALGTSIGKCPKNKL-FKVYIELEL--QLREFDRCRKLYEKFLEFGPENC 640
++QK SL + I P+ L +K +ELE+ +++E +L +K L
Sbjct: 625 VQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALA 684
Query: 641 TSWIKF-AELETILGDIDRARAIYELAISQPRLDMPEVLWK-SYIDFEIEQE----ETER 694
W K E E+++ I E + + +D+ + + + ++ E+++E ++ER
Sbjct: 685 EEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSER 744
Query: 695 TRNLYRRLLQRTQHVKVWISFAQFELSSGKEGSLTKCRQIYEEANKTMRNCEEKEERLML 754
RNL Q ++ I A+ + E K +Q+ E+ ++ + + E + +
Sbjct: 745 QRNL--------QELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKI 796
Query: 755 LES-WRSFEEEFGTASD---KERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYIFPEDA 810
LE ++ F+++ + + ++ L EKV+ RK+++ S +++ + E A
Sbjct: 797 LEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELA 856
Query: 811 ANQPNLKLLAMAKLWKKQQQEKE 833
+ + MA+L KKQQ+E E
Sbjct: 857 RLKQREQESQMARL-KKQQEELE 878
>gi|17149828 NMDA receptor regulated 1 [Homo sapiens]
Length = 866
Score = 36.2 bits (82), Expect = 0.13
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 615 LELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPRLDM 674
L++Q+R+ + R+ + L+ P SWI +A +L D + A I E + +
Sbjct: 123 LQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILE-EFRKTQQTS 181
Query: 675 PEVLWKSYIDFEIEQEETERTRNLYRRLLQ 704
P+ + Y + + Q + R LYR L+
Sbjct: 182 PDKVDYEYSELLLYQNQVLREAGLYREALE 211
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 35.4 bits (80), Expect = 0.22
Identities = 18/72 (25%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Query: 735 YEEANKTMRN---CEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTD 791
YE A K E+K++ L +E W +E F +KE++++ E++K+ K D
Sbjct: 537 YERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKKDKD 596
Query: 792 DGSDAGWEEYFD 803
+ +E++ +
Sbjct: 597 KQAINEYEKWLE 608
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 35.0 bits (79), Expect = 0.29
Identities = 130/688 (18%), Positives = 257/688 (37%), Gaps = 80/688 (11%)
Query: 186 EVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNW 245
E Q+ EQ LR ++ E QQ ++EE + +++ E +++ + +W
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 246 IKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNI----WDR 301
+K EE + ++ R + D + WLK E E + +Q + + +R
Sbjct: 458 LKR---EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER 514
Query: 302 AITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEE---QAWHSYINFELRYKE 358
L R + EE L + Q R E + E+ + + E R +
Sbjct: 515 REQRLKRQEE--------EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 359 VDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVE-------FFGDEHM 411
+ R + +L + + + R +E+ R+ ER + +E
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 412 DEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDI 471
+E E+ ++ +++R + ++ K++ +E + + +RR E
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR--EQE 684
Query: 472 IVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWK 531
+ + + Q E +K+ + W +ES+A+A +VY R P +++ +
Sbjct: 685 LAEEEQEQARERIKSRIPKWQ-W-----QLESEADARQ-SKVYSR------PRKQEGQRR 731
Query: 532 RYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSL 591
R EL+ ++ ER + Q ++ F W + E ++ LS
Sbjct: 732 RQEQEEKRRRRESELQWQEEERAHRQQQEE-----EQRRDFTWQWQAEEKSERGRQRLSA 786
Query: 592 ---ARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAE 648
R + + + + ++ E + + R R+ EK L+ F E
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ-----------FLE 835
Query: 649 LETILGDIDRARAIYE----LAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQ 704
E L +RA+ + E L Q R E +++E+E R LY +
Sbjct: 836 EEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPAL 895
Query: 705 RTQHVKVWISFAQFELSSGKEGSLTKCRQIYEEANKTMRNCEEKEERLML--LESWRSFE 762
+ Q K + E +E + RQ E + +++EE+L+ E R E
Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
Query: 763 EEFGTASDK---ERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLL 819
E DK ++ ++L+ E+ +KRR+ + + + E+ Q + L
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK------------YREEEELQQEEEQL 1003
Query: 820 AMAKLWKKQQQEKEDAEHHPDEDVDESE 847
+ K+++QE E DE E E
Sbjct: 1004 LREEREKRRRQEWERQYRKKDELQQEEE 1031
>gi|225690497 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 35.0 bits (79), Expect = 0.29
Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 8/128 (6%)
Query: 94 EDAQPGHHGNGAASVTAQARGQRSVLQVPLPVPRSCLFSESFVVSVSSQSRFLASVPGTG 153
E A+P + AS A Q S + L P S SE ++ VS Q F+ P
Sbjct: 358 ERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLL-VSWQRAFVDRTP--- 413
Query: 154 VQRSTAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQK 213
A +A TA G+ +P++ + +PA+ + +E EL L P
Sbjct: 414 ----PPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGF 469
Query: 214 ITDEEELN 221
+EEELN
Sbjct: 470 PREEEELN 477
>gi|225690495 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 35.0 bits (79), Expect = 0.29
Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 8/128 (6%)
Query: 94 EDAQPGHHGNGAASVTAQARGQRSVLQVPLPVPRSCLFSESFVVSVSSQSRFLASVPGTG 153
E A+P + AS A Q S + L P S SE ++ VS Q F+ P
Sbjct: 358 ERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLL-VSWQRAFVDRTP--- 413
Query: 154 VQRSTAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQK 213
A +A TA G+ +P++ + +PA+ + +E EL L P
Sbjct: 414 ----PPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGF 469
Query: 214 ITDEEELN 221
+EEELN
Sbjct: 470 PREEEELN 477
>gi|225690493 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 35.0 bits (79), Expect = 0.29
Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 8/128 (6%)
Query: 94 EDAQPGHHGNGAASVTAQARGQRSVLQVPLPVPRSCLFSESFVVSVSSQSRFLASVPGTG 153
E A+P + AS A Q S + L P S SE ++ VS Q F+ P
Sbjct: 358 ERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLL-VSWQRAFVDRTP--- 413
Query: 154 VQRSTAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQK 213
A +A TA G+ +P++ + +PA+ + +E EL L P
Sbjct: 414 ----PPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGF 469
Query: 214 ITDEEELN 221
+EEELN
Sbjct: 470 PREEEELN 477
>gi|225690491 tight junction associated protein 1 isoform b [Homo
sapiens]
Length = 547
Score = 35.0 bits (79), Expect = 0.29
Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 8/128 (6%)
Query: 94 EDAQPGHHGNGAASVTAQARGQRSVLQVPLPVPRSCLFSESFVVSVSSQSRFLASVPGTG 153
E A+P + AS A Q S + L P S SE ++ VS Q F+ P
Sbjct: 358 ERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLL-VSWQRAFVDRTP--- 413
Query: 154 VQRSTAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQK 213
A +A TA G+ +P++ + +PA+ + +E EL L P
Sbjct: 414 ----PPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGF 469
Query: 214 ITDEEELN 221
+EEELN
Sbjct: 470 PREEEELN 477
>gi|225690489 tight junction associated protein 1 isoform a [Homo
sapiens]
Length = 557
Score = 35.0 bits (79), Expect = 0.29
Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 8/128 (6%)
Query: 94 EDAQPGHHGNGAASVTAQARGQRSVLQVPLPVPRSCLFSESFVVSVSSQSRFLASVPGTG 153
E A+P + AS A Q S + L P S SE ++ VS Q F+ P
Sbjct: 368 ERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLL-VSWQRAFVDRTP--- 423
Query: 154 VQRSTAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQK 213
A +A TA G+ +P++ + +PA+ + +E EL L P
Sbjct: 424 ----PPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGF 479
Query: 214 ITDEEELN 221
+EEELN
Sbjct: 480 PREEEELN 487
>gi|225690487 tight junction associated protein 1 isoform a [Homo
sapiens]
Length = 557
Score = 35.0 bits (79), Expect = 0.29
Identities = 36/128 (28%), Positives = 53/128 (41%), Gaps = 8/128 (6%)
Query: 94 EDAQPGHHGNGAASVTAQARGQRSVLQVPLPVPRSCLFSESFVVSVSSQSRFLASVPGTG 153
E A+P + AS A Q S + L P S SE ++ VS Q F+ P
Sbjct: 368 ERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLL-VSWQRAFVDRTP--- 423
Query: 154 VQRSTAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQK 213
A +A TA G+ +P++ + +PA+ + +E EL L P
Sbjct: 424 ----PPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPEESELLLPTEPDSGF 479
Query: 214 ITDEEELN 221
+EEELN
Sbjct: 480 PREEEELN 487
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 35.0 bits (79), Expect = 0.29
Identities = 29/99 (29%), Positives = 54/99 (54%), Gaps = 5/99 (5%)
Query: 690 EETERTRNL-YRRLLQRTQHVKVWISFAQFELSSGK--EGSLTKCRQIYEEANKTMRNCE 746
E+TER+R L + L++ ++ V++ S ++ K E LT+ + EEA + RN E
Sbjct: 1695 EQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAE 1754
Query: 747 EKEERLMLLESWRSFE--EEFGTASDKERVDKLMPEKVK 783
EK ++ + + + E +E T++ ER+ K M + +K
Sbjct: 1755 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK 1793
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 34.7 bits (78), Expect = 0.38
Identities = 63/311 (20%), Positives = 127/311 (40%), Gaps = 42/311 (13%)
Query: 547 EAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRAL----GTSIGK 602
E + R R++ Q EL +K + + +L+ + + +A+ L G I
Sbjct: 1988 ETPETSRQRKMTQVEQELF-ERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFV 2046
Query: 603 CPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAI 662
+ KL K +L + + K L+ + K + E + + RA +
Sbjct: 2047 QGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFV 2106
Query: 663 YE--LAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFEL 720
E L+I Q +LD+ E ++ ++ +E T++ + L R Q +L
Sbjct: 2107 KERRLSIEQSKLDIKE--------WDFSEKRSELTKD--EKKLARKQR----------KL 2146
Query: 721 SSGKEGSLTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPE 780
++ + K ++ EE +K R E ++L+ EEE G ++E V +
Sbjct: 2147 ANKMRRMINKEEKMTEEESKLARKHSE-----VILDD----EEEGGI--EEEEVIPFLKR 2195
Query: 781 KVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLL----AMAKLWKKQQQEKEDAE 836
+ +KR++ + D + D + E+ ++ LL L ++++E+E+ E
Sbjct: 2196 RWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEE 2255
Query: 837 HHPDEDVDESE 847
+E+V E E
Sbjct: 2256 EREEEEVREEE 2266
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 34.7 bits (78), Expect = 0.38
Identities = 31/178 (17%), Positives = 70/178 (39%), Gaps = 10/178 (5%)
Query: 199 KERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEI 258
+E E+ PPPP K K K + E+++ +N+ + K+
Sbjct: 192 EEEEIATPPPPPPPK----------KETKPEPMEEDLPENKKQALKEKELGNDAYKKKDF 241
Query: 259 QRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTY 318
A Y++A ++D N+T A + + N R + ++AI + + +
Sbjct: 242 DTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAK 301
Query: 319 MEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDV 376
+GN + ++ + + + A H + + ++ ++ ER ++PD+
Sbjct: 302 AYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDL 359
Score = 30.0 bits (66), Expect = 9.4
Identities = 14/44 (31%), Positives = 26/44 (59%)
Query: 229 KTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVD 272
K E+ I+ T I + + A E++K+ +A +Y++ALD+D
Sbjct: 415 KDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLD 458
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 34.3 bits (77), Expect = 0.50
Identities = 24/97 (24%), Positives = 46/97 (47%), Gaps = 9/97 (9%)
Query: 153 GVQR----STAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPP 208
G++R +T+ D + Q+ + K + K+ + I+ E+ +++K++ PP
Sbjct: 976 GIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPP 1035
Query: 209 PPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNW 245
IT +EEL + K ED+ +K T S+W
Sbjct: 1036 -----ITTKEELVEMCNGKNGILEDSQKKEDTAFSDW 1067
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 33.9 bits (76), Expect = 0.65
Identities = 57/261 (21%), Positives = 110/261 (42%), Gaps = 29/261 (11%)
Query: 353 ELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEK----HAYFAHARKVYERAVEFFGD 408
EL + + ++I + L V+ K A EEK HA KV
Sbjct: 320 ELELEVLKHTQSIKSQNNLQEKLVQEKSKVADAEEKILDLQRKLEHAHKVCLTDTCISEK 379
Query: 409 EHMDEHLYVAF---AKFEENQKEFERVRVIYKYALDRISKQ-----DAQELFK-NYTIFE 459
+ ++E + A AK ++ +E ++ R + +D + +Q D + L + + +
Sbjct: 380 QQLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQ 439
Query: 460 KKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAI- 518
+ + + + +++R +Y+E VK+N + +L + E EA+RE Y R +
Sbjct: 440 SRIQQQEALLKQLENEKR-KYDEHVKSNQELSE------KLSKLQQEKEALREEYLRLLK 492
Query: 519 ---ANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKM 575
+V EK H ++ + Y L E+E +D +R Q ++ + ++ HK K
Sbjct: 493 LLNVHVRNYNEKHHQQKVKLQKVKYRLTNEVELRD-KRINQ-FEDEIGILQHK---IEKE 547
Query: 576 WILYAQFEIRQKNLSLARRAL 596
+ Q + L L +R L
Sbjct: 548 KAIQDQITAQNDTLLLEKRKL 568
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,997,658
Number of Sequences: 37866
Number of extensions: 1442175
Number of successful extensions: 5888
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 5505
Number of HSP's gapped (non-prelim): 296
length of query: 848
length of database: 18,247,518
effective HSP length: 111
effective length of query: 737
effective length of database: 14,044,392
effective search space: 10350716904
effective search space used: 10350716904
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.