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Search of human proteins with 38372925
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38372925 basigin isoform 2 precursor [Homo sapiens]
(269 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38372925 basigin isoform 2 precursor [Homo sapiens] 542 e-154
gi|38372919 basigin isoform 1 precursor [Homo sapiens] 499 e-142
gi|38372923 basigin isoform 4 [Homo sapiens] 397 e-111
gi|9257240 neuroplastin isoform a precursor [Homo sapiens] 176 1e-44
gi|6912646 neuroplastin isoform b precursor [Homo sapiens] 176 1e-44
gi|238624149 neuroplastin isoform d precursor [Homo sapiens] 170 1e-42
gi|238624147 neuroplastin isoform c precursor [Homo sapiens] 170 1e-42
gi|38348215 embigin [Homo sapiens] 67 1e-11
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 55 6e-08
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 55 6e-08
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 55 6e-08
gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] 51 9e-07
gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] 51 9e-07
gi|157168355 CD22 molecule [Homo sapiens] 49 5e-06
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 48 8e-06
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 48 8e-06
gi|118572606 hemicentin 1 [Homo sapiens] 46 3e-05
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] 46 4e-05
gi|13489095 sialoadhesin precursor [Homo sapiens] 45 5e-05
gi|166295173 kin of IRRE like [Homo sapiens] 45 7e-05
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 45 9e-05
gi|59939900 opioid binding protein/cell adhesion molecule-like i... 44 1e-04
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 44 1e-04
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 44 1e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 44 2e-04
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 43 3e-04
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 43 3e-04
gi|236464356 neuregulin 1 isoform HRG-gamma3 [Homo sapiens] 42 7e-04
gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens] 42 7e-04
gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens] 42 7e-04
>gi|38372925 basigin isoform 2 precursor [Homo sapiens]
Length = 269
Score = 542 bits (1396), Expect = e-154
Identities = 269/269 (100%), Positives = 269/269 (100%)
Query: 1 MAAALFVLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGV 60
MAAALFVLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGV
Sbjct: 1 MAAALFVLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGV 60
Query: 61 VLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGE 120
VLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGE
Sbjct: 61 VLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGE 120
Query: 121 TAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADP 180
TAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADP
Sbjct: 121 TAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADP 180
Query: 181 GQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLD 240
GQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLD
Sbjct: 181 GQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLD 240
Query: 241 DDDAGSAPLKSSGQHQNDKGKNVRQRNSS 269
DDDAGSAPLKSSGQHQNDKGKNVRQRNSS
Sbjct: 241 DDDAGSAPLKSSGQHQNDKGKNVRQRNSS 269
>gi|38372919 basigin isoform 1 precursor [Homo sapiens]
Length = 385
Score = 499 bits (1286), Expect = e-142
Identities = 246/246 (100%), Positives = 246/246 (100%)
Query: 24 GTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWG 83
GTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWG
Sbjct: 140 GTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWG 199
Query: 84 EYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKIT 143
EYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKIT
Sbjct: 200 EYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKIT 259
Query: 144 DSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 203
DSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR
Sbjct: 260 DSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 319
Query: 204 SHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNV 263
SHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNV
Sbjct: 320 SHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNV 379
Query: 264 RQRNSS 269
RQRNSS
Sbjct: 380 RQRNSS 385
Score = 52.4 bits (124), Expect = 4e-07
Identities = 42/134 (31%), Positives = 59/134 (44%), Gaps = 22/134 (16%)
Query: 1 MAAALFVLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGV 60
MAAALFVLLGFALLGTHGASGAAG V ++ RW+ G V
Sbjct: 1 MAAALFVLLGFALLGTHGASGAAGFV--------------------QAPLSQQRWVGGSV 40
Query: 61 VLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVK--SSEHINE 118
L +A+ E + + Q +C L + + +H A S + + E
Sbjct: 41 ELHCEAVGSPVPEIQWWFEGQGPNDTCSQLWDGARLDRVHIHATYHQHAASTISIDTLVE 100
Query: 119 GETAMLVCKSESVP 132
+T C++ + P
Sbjct: 101 EDTGTYECRASNDP 114
>gi|38372923 basigin isoform 4 [Homo sapiens]
Length = 205
Score = 397 bits (1020), Expect = e-111
Identities = 197/207 (95%), Positives = 200/207 (96%), Gaps = 4/207 (1%)
Query: 63 KEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA 122
+ DA P ++ VDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA
Sbjct: 3 QSDASPQER----VDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA 58
Query: 123 MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ 182
MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ
Sbjct: 59 MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ 118
Query: 183 YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD 242
YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD
Sbjct: 119 YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD 178
Query: 243 DAGSAPLKSSGQHQNDKGKNVRQRNSS 269
DAGSAPLKSSGQHQNDKGKNVRQRNSS
Sbjct: 179 DAGSAPLKSSGQHQNDKGKNVRQRNSS 205
>gi|9257240 neuroplastin isoform a precursor [Homo sapiens]
Length = 282
Score = 176 bits (447), Expect = 1e-44
Identities = 95/237 (40%), Positives = 142/237 (59%), Gaps = 8/237 (3%)
Query: 37 ILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPE 92
+ L C+L S+ +T W K GV L E++++ + GEY CV F+
Sbjct: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSA 109
Query: 93 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 152
P A I++ P + K SE+ NEG+ A + CKS P DW W K + ++N
Sbjct: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVN 168
Query: 153 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF 212
S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + LRVRSHLA LWPF
Sbjct: 169 TS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPF 227
Query: 213 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 269
LGI+AE+++LV II +YEKR++P++V DDD+ + P+K++ + N K KN+RQRN++
Sbjct: 228 LGILAEIIILVVIIVVYEKRKRPDEVPDDDEP-AGPMKTNSTN-NHKDKNLRQRNTN 282
>gi|6912646 neuroplastin isoform b precursor [Homo sapiens]
Length = 398
Score = 176 bits (447), Expect = 1e-44
Identities = 95/237 (40%), Positives = 142/237 (59%), Gaps = 8/237 (3%)
Query: 37 ILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPE 92
+ L C+L S+ +T W K GV L E++++ + GEY CV F+
Sbjct: 166 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSA 225
Query: 93 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 152
P A I++ P + K SE+ NEG+ A + CKS P DW W K + ++N
Sbjct: 226 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVN 284
Query: 153 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF 212
S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + LRVRSHLA LWPF
Sbjct: 285 TS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPF 343
Query: 213 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 269
LGI+AE+++LV II +YEKR++P++V DDD+ + P+K++ + N K KN+RQRN++
Sbjct: 344 LGILAEIIILVVIIVVYEKRKRPDEVPDDDEP-AGPMKTNSTN-NHKDKNLRQRNTN 398
>gi|238624149 neuroplastin isoform d precursor [Homo sapiens]
Length = 278
Score = 170 bits (430), Expect = 1e-42
Identities = 93/237 (39%), Positives = 139/237 (58%), Gaps = 12/237 (5%)
Query: 37 ILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPE 92
+ L C+L S+ +T W K GV L E++++ + GEY CV F+
Sbjct: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSA 109
Query: 93 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 152
P A I++ P + K SE+ NEG+ A + CKS P DW W K + ++N
Sbjct: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVN 168
Query: 153 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF 212
S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + LRVRSHLA LWPF
Sbjct: 169 TS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPF 227
Query: 213 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 269
LGI+AE+++LV II +YEKR++P++V D + P+K++ + N K KN+RQRN++
Sbjct: 228 LGILAEIIILVVIIVVYEKRKRPDEVPD-----AGPMKTNSTN-NHKDKNLRQRNTN 278
>gi|238624147 neuroplastin isoform c precursor [Homo sapiens]
Length = 394
Score = 170 bits (430), Expect = 1e-42
Identities = 93/237 (39%), Positives = 139/237 (58%), Gaps = 12/237 (5%)
Query: 37 ILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPE 92
+ L C+L S+ +T W K GV L E++++ + GEY CV F+
Sbjct: 166 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSA 225
Query: 93 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 152
P A I++ P + K SE+ NEG+ A + CKS P DW W K + ++N
Sbjct: 226 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVN 284
Query: 153 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF 212
S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + LRVRSHLA LWPF
Sbjct: 285 TS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPF 343
Query: 213 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 269
LGI+AE+++LV II +YEKR++P++V D + P+K++ + N K KN+RQRN++
Sbjct: 344 LGILAEIIILVVIIVVYEKRKRPDEVPD-----AGPMKTNSTN-NHKDKNLRQRNTN 394
>gi|38348215 embigin [Homo sapiens]
Length = 327
Score = 67.4 bits (163), Expect = 1e-11
Identities = 66/216 (30%), Positives = 96/216 (44%), Gaps = 33/216 (15%)
Query: 35 SKILLTCSLNDS----ATEVTGHRWLKGGVVLKEDALPGQ-------KTEFKVDSDDQWG 83
S + LTC S A VT W K G L+ + L + F + + Q G
Sbjct: 82 SNVNLTCQFTTSGDLNAVNVT---WKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMG 138
Query: 84 EYSCVFLPEP--MGTANI---QLHGP--PRVKAVKSSEHINEGETAMLVCKSESVPPVTD 136
YSC F E GT N +LHG P + V G++ +L CK ++ P+ +
Sbjct: 139 SYSCFFREEKEQRGTFNFKVPELHGKNKPLISYV--------GDSTVLTCKCQNCFPL-N 189
Query: 137 WAWYKITDSEDKALMNGSESRFFVSSSQGR-SELHIENLNMEADPGQYRCNGTSSKGSDQ 195
W WY S K + +++ ++ + ++L I L +E D Y C G +
Sbjct: 190 WTWYSSNGSV-KVPVGVQMNKYVINGTYANETKLKITQL-LEEDGESYWCRALFQLGESE 247
Query: 196 AIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEK 231
I L V S+L L PFL IVAEV++LV I + EK
Sbjct: 248 EHIELVVLSYLVPLKPFLVIVAEVILLVATILLCEK 283
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 55.1 bits (131), Expect = 6e-08
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 24/177 (13%)
Query: 36 KILLTCSLN-DSATEVTGHRWLKGGVVLKEDALP-----GQKTEFKVDSDDQWGEYSCVF 89
+++L CS+ + A ++T HR G+VL+EDA G+ + + S G+YSC
Sbjct: 2407 QLVLECSVEAEPAPKITWHR---DGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTA 2463
Query: 90 LPEPMGTA---NIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDS 145
T+ +++H P +++ + +++ +TA+L C+++ VP P+ W
Sbjct: 2464 RNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-------R 2516
Query: 146 EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
+D+ ++ RF + L I+ + + D G Y C ++S GSD+ LRV
Sbjct: 2517 KDRVPLDPRSPRFEILP---EGSLRIQPV-LAQDAGHYLCLASNSAGSDRQGRDLRV 2569
Score = 42.7 bits (99), Expect = 3e-04
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 22/186 (11%)
Query: 28 TTVEDLGSKILLTCSLND-SATEVTGHRWLKGGVVLKEDALPGQ-----KTEFKVDSDDQ 81
T + GS ++LTC ++ A VT WLK + ++ A+ G + + Q
Sbjct: 1942 TVSQVAGSPLVLTCDVSGVPAPTVT---WLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQ 1998
Query: 82 WGEYSCVF---LPEPMGTANIQLHGPPRVKA--VKSSEHINEGETAMLVCKSESVPPVTD 136
G Y+CV E + + PR+++ V H+ EG+ L C+++ PP D
Sbjct: 1999 AGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PD 2057
Query: 137 WAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQA 196
AW K D G RF++ L ++ L +D G Y C + G D
Sbjct: 2058 VAWLK--DGSPLGQDMGPHLRFYLDG----GSLVLKGLR-ASDAGAYTCVAHNPAGEDAR 2110
Query: 197 IITLRV 202
+ T+ V
Sbjct: 2111 LHTVNV 2116
Score = 42.0 bits (97), Expect = 6e-04
Identities = 42/162 (25%), Positives = 64/162 (39%), Gaps = 23/162 (14%)
Query: 55 WLKGGVVL----KEDALPGQKTEFKVDSDDQWGEYSCVF---LPEPMGTANIQLHGPPRV 107
W K G+ + LPG + S + G Y C+ MG + + PP +
Sbjct: 2790 WQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVI 2849
Query: 108 KAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRS 167
+ EG A L CK+ P IT +D ++G+E +F + S
Sbjct: 2850 ENGLPDLSTTEGSHAFLPCKARGSPEP------NITWDKDGQPVSGAEGKFTIQPS---G 2900
Query: 168 ELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAAL 209
EL ++NL + D G Y C ++ A+ R R HL L
Sbjct: 2901 ELLVKNLEGQ-DAGTYTCT------AENAVGRARRRVHLTIL 2935
Score = 39.3 bits (90), Expect = 0.004
Identities = 42/181 (23%), Positives = 74/181 (40%), Gaps = 24/181 (13%)
Query: 33 LGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQK--------TEFKVDSDDQWGE 84
+ + + LTC+ + + WLK G + PG + T + D G
Sbjct: 800 VNTPVRLTCNATGAPSPTL--MWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDS-GR 856
Query: 85 YSCVFLP---EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYK 141
YSCV + E +Q+H PP + + + + E+ L C+S ++PP +W+K
Sbjct: 857 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPV-LSWWK 915
Query: 142 ITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLR 201
+ + L E R V S ++ L ++ ++ D G Y C + G + L
Sbjct: 916 ----DGRPL----EPRPGVHLSADKALLQVDRADV-WDAGHYTCEALNQAGRSEKHYNLN 966
Query: 202 V 202
V
Sbjct: 967 V 967
Score = 33.9 bits (76), Expect = 0.15
Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 14/131 (10%)
Query: 75 KVDSDDQWGEYSCV---FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESV 131
KVD D+ G Y+C E +++ PP ++ ++ + E + L C + V
Sbjct: 663 KVDLRDE-GIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGV 721
Query: 132 PPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSK 191
PP D +W+K S V+ S L IE + +D G YRC ++
Sbjct: 722 PP-PDVSWFKGHQPVS--------SWMGVTVSVDGRVLRIEQAQL-SDAGSYRCVASNVA 771
Query: 192 GSDQAIITLRV 202
GS + LRV
Sbjct: 772 GSTELRYGLRV 782
Score = 28.5 bits (62), Expect = 6.4
Identities = 29/117 (24%), Positives = 48/117 (41%), Gaps = 23/117 (19%)
Query: 92 EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP------PVTDWAWYKITDS 145
E + T +Q+ PPR+ + + ++ S S+P P + WYK
Sbjct: 1735 EKLFTLRVQV--PPRIAGLDLEQ------VTAILNSSVSLPCDVHAHPNPEVTWYK---- 1782
Query: 146 EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
+ +AL G E V G L + + +D G Y C ++ G DQ ++ L V
Sbjct: 1783 DSQALSLGEE----VFLLPGTHTLQLGRARL-SDSGMYTCEALNAAGRDQKLVQLSV 1834
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 55.1 bits (131), Expect = 6e-08
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 24/177 (13%)
Query: 36 KILLTCSLN-DSATEVTGHRWLKGGVVLKEDALP-----GQKTEFKVDSDDQWGEYSCVF 89
+++L CS+ + A ++T HR G+VL+EDA G+ + + S G+YSC
Sbjct: 3598 QLVLECSVEAEPAPKITWHR---DGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTA 3654
Query: 90 LPEPMGTA---NIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDS 145
T+ +++H P +++ + +++ +TA+L C+++ VP P+ W
Sbjct: 3655 RNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-------R 3707
Query: 146 EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
+D+ ++ RF + L I+ + + D G Y C ++S GSD+ LRV
Sbjct: 3708 KDRVPLDPRSPRFEILP---EGSLRIQPV-LAQDAGHYLCLASNSAGSDRQGRDLRV 3760
Score = 42.7 bits (99), Expect = 3e-04
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 22/186 (11%)
Query: 28 TTVEDLGSKILLTCSLND-SATEVTGHRWLKGGVVLKEDALPGQ-----KTEFKVDSDDQ 81
T + GS ++LTC ++ A VT WLK + ++ A+ G + + Q
Sbjct: 3133 TVSQVAGSPLVLTCDVSGVPAPTVT---WLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQ 3189
Query: 82 WGEYSCVF---LPEPMGTANIQLHGPPRVKA--VKSSEHINEGETAMLVCKSESVPPVTD 136
G Y+CV E + + PR+++ V H+ EG+ L C+++ PP D
Sbjct: 3190 AGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PD 3248
Query: 137 WAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQA 196
AW K D G RF++ L ++ L +D G Y C + G D
Sbjct: 3249 VAWLK--DGSPLGQDMGPHLRFYLDG----GSLVLKGLR-ASDAGAYTCVAHNPAGEDAR 3301
Query: 197 IITLRV 202
+ T+ V
Sbjct: 3302 LHTVNV 3307
Score = 42.0 bits (97), Expect = 6e-04
Identities = 42/162 (25%), Positives = 64/162 (39%), Gaps = 23/162 (14%)
Query: 55 WLKGGVVL----KEDALPGQKTEFKVDSDDQWGEYSCVF---LPEPMGTANIQLHGPPRV 107
W K G+ + LPG + S + G Y C+ MG + + PP +
Sbjct: 3981 WQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVI 4040
Query: 108 KAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRS 167
+ EG A L CK+ P IT +D ++G+E +F + S
Sbjct: 4041 ENGLPDLSTTEGSHAFLPCKARGSPEP------NITWDKDGQPVSGAEGKFTIQPS---G 4091
Query: 168 ELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAAL 209
EL ++NL + D G Y C ++ A+ R R HL L
Sbjct: 4092 ELLVKNLEGQ-DAGTYTCT------AENAVGRARRRVHLTIL 4126
Score = 41.2 bits (95), Expect = 0.001
Identities = 45/176 (25%), Positives = 66/176 (37%), Gaps = 22/176 (12%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVLKEDA---LPGQKTEF-KVDSDDQWGEYSCVF 89
G ++ ++CS + T W + L+ED+ + Q T + + + G YSC
Sbjct: 622 GVEVKVSCSASGYPTPHIS--WSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA 679
Query: 90 LPE---PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSE 146
E T + PP V AV + + GE A+LVC++ VPP WY+
Sbjct: 680 TNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPP-PRVIWYR----- 733
Query: 147 DKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
G +L I E D G Y C + G A I L V
Sbjct: 734 ------GGLEMILAPEGSSSGKLRIP-AAQERDAGTYTCRAVNELGDASAEIQLAV 782
Score = 39.3 bits (90), Expect = 0.004
Identities = 42/181 (23%), Positives = 74/181 (40%), Gaps = 24/181 (13%)
Query: 33 LGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQK--------TEFKVDSDDQWGE 84
+ + + LTC+ + + WLK G + PG + T + D G
Sbjct: 1991 VNTPVRLTCNATGAPSPTL--MWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDS-GR 2047
Query: 85 YSCVFLP---EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYK 141
YSCV + E +Q+H PP + + + + E+ L C+S ++PP +W+K
Sbjct: 2048 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPV-LSWWK 2106
Query: 142 ITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLR 201
+ + L E R V S ++ L ++ ++ D G Y C + G + L
Sbjct: 2107 ----DGRPL----EPRPGVHLSADKALLQVDRADV-WDAGHYTCEALNQAGHSEKHYNLN 2157
Query: 202 V 202
V
Sbjct: 2158 V 2158
Score = 38.1 bits (87), Expect = 0.008
Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 13/97 (13%)
Query: 105 PRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDSEDKALMNGSESRFFVSSS 163
P+V SS+H ++G + C + P P W+ E +AL +SR V +
Sbjct: 608 PQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWS------RESQALQ--EDSRIHVDA- 658
Query: 164 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 200
+ L I+ + E D G Y C T+ G+DQ +TL
Sbjct: 659 --QGTLIIQGVAPE-DAGNYSCQATNEVGTDQETVTL 692
Score = 33.9 bits (76), Expect = 0.15
Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 14/131 (10%)
Query: 75 KVDSDDQWGEYSCV---FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESV 131
KVD D+ G Y+C E +++ PP ++ ++ + E + L C + V
Sbjct: 1854 KVDLRDE-GIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGV 1912
Query: 132 PPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSK 191
PP D +W+K S V+ S L IE + +D G YRC ++
Sbjct: 1913 PP-PDVSWFKGHQPVS--------SWMGVTVSVDGRVLRIEQAQL-SDAGSYRCVASNVA 1962
Query: 192 GSDQAIITLRV 202
GS + LRV
Sbjct: 1963 GSTELRYGLRV 1973
Score = 33.5 bits (75), Expect = 0.20
Identities = 45/164 (27%), Positives = 59/164 (35%), Gaps = 35/164 (21%)
Query: 55 WLKGGVVLKEDALPGQKTEFKVDSD--------DQWGEYSCVFLPEPMGTANIQ------ 100
WLK G L PG + + D + G YSCV TA Q
Sbjct: 919 WLKDGRPLP----PGSRHSIRADGSLHLDRALQEHAGRYSCV----ATNTAGSQHRDVEL 970
Query: 101 -LHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDSEDKALMNGSESRF 158
+ PPR+ + NEG A L C + VP P W E AL S
Sbjct: 971 VVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWT------KETNALT--SRGPH 1022
Query: 159 FVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
+ S +G L I + + D G Y C T++ G + L V
Sbjct: 1023 YNVSKEG--TLLIAQPSAQ-DAGAYVCTATNTVGFSSQEMRLSV 1063
Score = 33.1 bits (74), Expect = 0.26
Identities = 37/153 (24%), Positives = 62/153 (40%), Gaps = 25/153 (16%)
Query: 65 DALPGQKTEFKVDSDDQW----------GEYSCVFLPEPMGT----ANIQLHGPPRVKAV 110
+A G++ F+ + W G Y C + GT A I + PP
Sbjct: 464 EARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRA-GTGRAKAQIVVTDPPPQLVP 522
Query: 111 KSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELH 170
+ ++ GETA+L C+ V A Y +T D ++ S R + L
Sbjct: 523 APNVTVSPGETAVLSCR------VLGEAPYNLTWVRDWRVLPASTGRV---AQLADLSLE 573
Query: 171 IENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 203
I + + D G+Y+C +++ G +A + L VR
Sbjct: 574 ISGI-IPTDGGRYQCVASNANGVTRASVWLLVR 605
Score = 33.1 bits (74), Expect = 0.26
Identities = 24/102 (23%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 102 HGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVS 161
H PP++ + + + EG+ L C + P+ + W K + + L GS
Sbjct: 882 HAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLK----DGRPLPPGSR-----H 932
Query: 162 SSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 203
S + LH++ ++ G+Y C T++ GS + L V+
Sbjct: 933 SIRADGSLHLDRA-LQEHAGRYSCVATNTAGSQHRDVELVVQ 973
Score = 33.1 bits (74), Expect = 0.26
Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 23/125 (18%)
Query: 83 GEYSCVFLPEPMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDW 137
G Y C P G+A+ + + PP+V+ + GE L C +E P P W
Sbjct: 1095 GHYECT-ASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSW 1153
Query: 138 AWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAI 197
S+D ++ G + V + R+ +D G+YRC ++S G D
Sbjct: 1154 -------SKDGVVLQGRGPQGSVHFAAIRT----------SDAGRYRCEASNSAGVDAWE 1196
Query: 198 ITLRV 202
+ LRV
Sbjct: 1197 VELRV 1201
Score = 32.0 bits (71), Expect = 0.58
Identities = 36/157 (22%), Positives = 62/157 (39%), Gaps = 11/157 (7%)
Query: 55 WLKGGV--VLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLH----GPPRVK 108
W +GG+ +L + K + G Y+C + E +G A+ ++ P++
Sbjct: 731 WYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNE-LGDASAEIQLAVGHAPQLT 789
Query: 109 AVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSE 168
+ + G +A+L C++ PP T ++ D + L G+ R S
Sbjct: 790 ELPRDVTVELGRSALLACRATGRPPPT--VTWRRGDGQPLGLRLGA-GRGSRSRQPDSGV 846
Query: 169 LHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSH 205
L E++ E D Y C + G QA L V H
Sbjct: 847 LFFESVAPE-DQAPYVCEARNVFGKVQAEARLIVTGH 882
Score = 28.5 bits (62), Expect = 6.4
Identities = 29/117 (24%), Positives = 48/117 (41%), Gaps = 23/117 (19%)
Query: 92 EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP------PVTDWAWYKITDS 145
E + T +Q+ PPR+ + + ++ S S+P P + WYK
Sbjct: 2926 EKLFTLRVQV--PPRIAGLDLEQ------VTAILNSSVSLPCDVHAHPNPEVTWYK---- 2973
Query: 146 EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
+ +AL G E V G L + + +D G Y C ++ G DQ ++ L V
Sbjct: 2974 DSQALSLGEE----VFLLPGTHTLQLGRARL-SDSGMYTCEALNAAGRDQKLVQLSV 3025
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 55.1 bits (131), Expect = 6e-08
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 24/177 (13%)
Query: 36 KILLTCSLN-DSATEVTGHRWLKGGVVLKEDALP-----GQKTEFKVDSDDQWGEYSCVF 89
+++L CS+ + A ++T HR G+VL+EDA G+ + + S G+YSC
Sbjct: 2316 QLVLECSVEAEPAPKITWHR---DGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTA 2372
Query: 90 LPEPMGTA---NIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDS 145
T+ +++H P +++ + +++ +TA+L C+++ VP P+ W
Sbjct: 2373 RNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-------R 2425
Query: 146 EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
+D+ ++ RF + L I+ + + D G Y C ++S GSD+ LRV
Sbjct: 2426 KDRVPLDPRSPRFEILP---EGSLRIQPV-LAQDAGHYLCLASNSAGSDRQGRDLRV 2478
Score = 42.7 bits (99), Expect = 3e-04
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 22/186 (11%)
Query: 28 TTVEDLGSKILLTCSLND-SATEVTGHRWLKGGVVLKEDALPGQ-----KTEFKVDSDDQ 81
T + GS ++LTC ++ A VT WLK + ++ A+ G + + Q
Sbjct: 1851 TVSQVAGSPLVLTCDVSGVPAPTVT---WLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQ 1907
Query: 82 WGEYSCVF---LPEPMGTANIQLHGPPRVKA--VKSSEHINEGETAMLVCKSESVPPVTD 136
G Y+CV E + + PR+++ V H+ EG+ L C+++ PP D
Sbjct: 1908 AGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PD 1966
Query: 137 WAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQA 196
AW K D G RF++ L ++ L +D G Y C + G D
Sbjct: 1967 VAWLK--DGSPLGQDMGPHLRFYLDG----GSLVLKGLR-ASDAGAYTCVAHNPAGEDAR 2019
Query: 197 IITLRV 202
+ T+ V
Sbjct: 2020 LHTVNV 2025
Score = 42.0 bits (97), Expect = 6e-04
Identities = 42/162 (25%), Positives = 64/162 (39%), Gaps = 23/162 (14%)
Query: 55 WLKGGVVL----KEDALPGQKTEFKVDSDDQWGEYSCVF---LPEPMGTANIQLHGPPRV 107
W K G+ + LPG + S + G Y C+ MG + + PP +
Sbjct: 2699 WQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVI 2758
Query: 108 KAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRS 167
+ EG A L CK+ P IT +D ++G+E +F + S
Sbjct: 2759 ENGLPDLSTTEGSHAFLPCKARGSPEP------NITWDKDGQPVSGAEGKFTIQPS---G 2809
Query: 168 ELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAAL 209
EL ++NL + D G Y C ++ A+ R R HL L
Sbjct: 2810 ELLVKNLEGQ-DAGTYTCT------AENAVGRARRRVHLTIL 2844
Score = 39.3 bits (90), Expect = 0.004
Identities = 42/181 (23%), Positives = 74/181 (40%), Gaps = 24/181 (13%)
Query: 33 LGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQK--------TEFKVDSDDQWGE 84
+ + + LTC+ + + WLK G + PG + T + D G
Sbjct: 709 VNTPVRLTCNATGAPSPTL--MWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDS-GR 765
Query: 85 YSCVFLP---EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYK 141
YSCV + E +Q+H PP + + + + E+ L C+S ++PP +W+K
Sbjct: 766 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPV-LSWWK 824
Query: 142 ITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLR 201
+ + L E R V S ++ L ++ ++ D G Y C + G + L
Sbjct: 825 ----DGRPL----EPRPGVHLSADKALLQVDRADV-WDAGHYTCEALNQAGHSEKHYNLN 875
Query: 202 V 202
V
Sbjct: 876 V 876
Score = 33.9 bits (76), Expect = 0.15
Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 14/131 (10%)
Query: 75 KVDSDDQWGEYSCV---FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESV 131
KVD D+ G Y+C E +++ PP ++ ++ + E + L C + V
Sbjct: 572 KVDLRDE-GIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGV 630
Query: 132 PPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSK 191
PP D +W+K S V+ S L IE + +D G YRC ++
Sbjct: 631 PP-PDVSWFKGHQPVS--------SWMGVTVSVDGRVLRIEQAQL-SDAGSYRCVASNVA 680
Query: 192 GSDQAIITLRV 202
GS + LRV
Sbjct: 681 GSTELRYGLRV 691
Score = 28.5 bits (62), Expect = 6.4
Identities = 29/117 (24%), Positives = 48/117 (41%), Gaps = 23/117 (19%)
Query: 92 EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP------PVTDWAWYKITDS 145
E + T +Q+ PPR+ + + ++ S S+P P + WYK
Sbjct: 1644 EKLFTLRVQV--PPRIAGLDLEQ------VTAILNSSVSLPCDVHAHPNPEVTWYK---- 1691
Query: 146 EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
+ +AL G E V G L + + +D G Y C ++ G DQ ++ L V
Sbjct: 1692 DSQALSLGEE----VFLLPGTHTLQLGRARL-SDSGMYTCEALNAAGRDQKLVQLSV 1743
>gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]
Length = 600
Score = 51.2 bits (121), Expect = 9e-07
Identities = 57/207 (27%), Positives = 93/207 (44%), Gaps = 27/207 (13%)
Query: 32 DLGSKILLTCSL--NDSATEVTGHRWLK--GGVVLKEDALPGQKTEFKVDSDDQWGEYSC 87
DLGS + +C+ N S T V W+K GVVL + K+ + D+ G+Y C
Sbjct: 347 DLGSDAIFSCAWTGNPSLTIV----WMKRGSGVVLSNEKTLTLKSVRQEDA----GKYVC 398
Query: 88 VFLPEPMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKIT 143
+ +G + ++GPP + + ++ +H GE + C S PP AW
Sbjct: 399 RAVVPRVGAGEREVTLTVNGPPIISSTQT-QHALHGEKGQIKCFIRSTPPPDRIAW---- 453
Query: 144 DSEDKALMNGSESRFFV---SSSQG-RSELHIENLNMEADPGQYRCNGTSSKGSDQAIIT 199
++ L +G+ R+ V S+ +G S L I N+ Y C +S GSD II
Sbjct: 454 SWKENVLESGTSGRYTVETISTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEII- 512
Query: 200 LRVRSHLAALWPFLGIVAEVLVLVTII 226
R++ + + G+ AE + + II
Sbjct: 513 -RLKEQGSEMKSGAGLEAESVPMAVII 538
>gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]
Length = 778
Score = 51.2 bits (121), Expect = 9e-07
Identities = 57/207 (27%), Positives = 93/207 (44%), Gaps = 27/207 (13%)
Query: 32 DLGSKILLTCSL--NDSATEVTGHRWLK--GGVVLKEDALPGQKTEFKVDSDDQWGEYSC 87
DLGS + +C+ N S T V W+K GVVL + K+ + D+ G+Y C
Sbjct: 347 DLGSDAIFSCAWTGNPSLTIV----WMKRGSGVVLSNEKTLTLKSVRQEDA----GKYVC 398
Query: 88 VFLPEPMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKIT 143
+ +G + ++GPP + + ++ +H GE + C S PP AW
Sbjct: 399 RAVVPRVGAGEREVTLTVNGPPIISSTQT-QHALHGEKGQIKCFIRSTPPPDRIAW---- 453
Query: 144 DSEDKALMNGSESRFFV---SSSQG-RSELHIENLNMEADPGQYRCNGTSSKGSDQAIIT 199
++ L +G+ R+ V S+ +G S L I N+ Y C +S GSD II
Sbjct: 454 SWKENVLESGTSGRYTVETISTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEII- 512
Query: 200 LRVRSHLAALWPFLGIVAEVLVLVTII 226
R++ + + G+ AE + + II
Sbjct: 513 -RLKEQGSEMKSGAGLEAESVPMAVII 538
>gi|157168355 CD22 molecule [Homo sapiens]
Length = 847
Score = 48.9 bits (115), Expect = 5e-06
Identities = 42/169 (24%), Positives = 78/169 (46%), Gaps = 26/169 (15%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEP 93
G+ + L C + S + W K G +L +++ + F S + G YSC
Sbjct: 522 GNSVSLQCDFSSSHPKEVQFFWEKNGRLLGKES----QLNFDSISPEDAGSYSCWVNNSI 577
Query: 94 MGTANIQ-----LHGPPRVKAVKS-SEHINEGETAMLVCKSESVPPVTDWAWYKITDSED 147
TA+ L+ P R++ S + + EG++A L C+S++ PPV+ + W+ D +
Sbjct: 578 GQTASKAWTLEVLYAPRRLRVSMSPGDQVMEGKSATLTCESDANPPVSHYTWF---DWNN 634
Query: 148 KALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQA 196
++L S+ +L +E + ++ G Y C GT+S G ++
Sbjct: 635 QSLPYHSQ------------KLRLEPVKVQ-HSGAYWCQGTNSVGKGRS 670
Score = 40.8 bits (94), Expect = 0.001
Identities = 50/185 (27%), Positives = 71/185 (38%), Gaps = 59/185 (31%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKT---EFKVDSDDQWGEYSC--- 87
G + +TC ++ S E T WLK G LK+ Q T + + DQ G+Y C
Sbjct: 258 GDSVTMTCEVSSSNPEYTTVSWLKDGTSLKK-----QNTFTLNLREVTKDQSGKYCCQVS 312
Query: 88 ----------VFL-----PEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP 132
VFL PEP + +Q+ P V EG +C S + P
Sbjct: 313 NDVGPGRSEEVFLQVQYAPEP---STVQILHSPAV----------EGSQVEFLCMSLANP 359
Query: 133 PVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSE--LHIENLNMEADPGQYRCNGTSS 190
T++ WY NG E QGR+E +HI + + G Y C +
Sbjct: 360 LPTNYTWYH----------NGKE-------MQGRTEEKVHIPKI-LPWHAGTYSCVAENI 401
Query: 191 KGSDQ 195
G+ Q
Sbjct: 402 LGTGQ 406
Score = 32.3 bits (72), Expect = 0.44
Identities = 41/169 (24%), Positives = 66/169 (39%), Gaps = 35/169 (20%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGV-------VLKEDALPGQKTEFKVDSDDQWGEYS 86
G + L+C+ N S VT + W G VLK + T + + W ++
Sbjct: 435 GDTVTLSCNYNSSNPSVTRYEWKPHGAWEEPSLGVLKIQNVGWDNTTIACAACNSWCSWA 494
Query: 87 CVFLPEPMGTANIQLHGP--PRVKAVKSSEHINEGETAMLVCK-SESVPPVTDWAWYKIT 143
P+ N+Q + P RV+ +K I+ G + L C S S P + W
Sbjct: 495 -----SPV-ALNVQ-YAPRDVRVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQFFW---- 543
Query: 144 DSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKG 192
E + G E S+L+ ++++ E D G Y C +S G
Sbjct: 544 --EKNGRLLGKE-----------SQLNFDSISPE-DAGSYSCWVNNSIG 578
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 48.1 bits (113), Expect = 8e-06
Identities = 52/183 (28%), Positives = 79/183 (43%), Gaps = 32/183 (17%)
Query: 32 DLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTE-----------FKVDSDD 80
+ G+ +L+C + + TEVT W K G L + G + + K D+
Sbjct: 1087 EAGASAMLSCEVAQAQTEVT---WYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADA-- 1141
Query: 81 QWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEH----INEGETAMLVCKSESVPPVTD 136
GEYSC + + + ++ + P V A + S H G TAML C E P T+
Sbjct: 1142 --GEYSCEAGGQRV-SFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSC--EVAQPQTE 1196
Query: 137 WAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQA 196
WYK + K L + S+ R V R L ++ + +AD G+Y C + S Q
Sbjct: 1197 VTWYK----DGKKLSSSSKVRMEVKGCTRR--LVVQQVG-KADAGEYSCEAGGQRVSFQL 1249
Query: 197 IIT 199
IT
Sbjct: 1250 HIT 1252
Score = 39.7 bits (91), Expect = 0.003
Identities = 49/177 (27%), Positives = 75/177 (42%), Gaps = 23/177 (12%)
Query: 34 GSKILLTCSLNDSATEV--TGHRWLKGGV--VLKEDALPGQKTEFKVD--SDDQWGEYSC 87
G L C L+ +A GH L+ G L++D G + E ++ + GEYSC
Sbjct: 3728 GDTATLWCELSKAAPVEWRKGHETLRDGDRHSLRQD---GSRCELQIRGLAVVDAGEYSC 3784
Query: 88 VFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSED 147
V E P R ++ EG TA+L C+ PV W K +++
Sbjct: 3785 VCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAPV---EWRKGSET-- 3839
Query: 148 KALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRS 204
+ G + R+ + R EL I L++ AD G+Y C G ++ TL VR+
Sbjct: 3840 ---LRGGD-RYSLRQDGTRCELQIHGLSV-ADTGEYSC----VCGQERTSATLTVRA 3887
Score = 38.5 bits (88), Expect = 0.006
Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 27/188 (14%)
Query: 32 DLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDAL------PGQKTEFKVDS--DDQWG 83
+LG + L C + + V W K G ++ D P +DS G
Sbjct: 6026 ELGETVKLACRVTGTPKPVIS--WYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSG 6083
Query: 84 EYSCVFLPEPMGTAN----IQLHGPPR-VKAVKSSEHINEGETAMLVCKSESVPPVTDWA 138
+Y C F G + I + PPR V V++S + EGE A C E P
Sbjct: 6084 QYMC-FAASAAGNCSTLGKILVQVPPRFVNKVRASPFV-EGEDAQFTCTIEGAP-YPQIR 6140
Query: 139 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEA--DPGQYRCNGTSSKGSDQA 196
WYK D AL+ F + S+ RS L + + + D G Y C + GS +A
Sbjct: 6141 WYK-----DGALLTTGNK--FQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARA 6193
Query: 197 IITLRVRS 204
LR++S
Sbjct: 6194 SAELRIQS 6201
Score = 36.6 bits (83), Expect = 0.024
Identities = 38/121 (31%), Positives = 58/121 (47%), Gaps = 16/121 (13%)
Query: 83 GEYSCVFLPEPMGTANIQLHGPPR--VKAVKSSEHINEGETAMLVCKSESVPPVTDWAWY 140
GEY CV E +A + + P ++ VK+ E EG TA+L C+ S PV W
Sbjct: 3516 GEYLCVCGQERT-SATLTIRALPARFIEDVKNQE-AREGATAVLQCELNSAAPV---EWR 3570
Query: 141 KITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 200
K +++ L +G R+ + + EL I L M AD G+Y C + A++T+
Sbjct: 3571 KGSET----LRDG--DRYSLRQDGTKCELQIRGLAM-ADTGEYSC--VCGQERTSAMLTV 3621
Query: 201 R 201
R
Sbjct: 3622 R 3622
Score = 33.9 bits (76), Expect = 0.15
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 23/177 (12%)
Query: 34 GSKILLTCSLNDSATEV--TGHRWLKGGV--VLKEDALPGQKTEFKVDS--DDQWGEYSC 87
G+ +L C L+ A GH L+ G L++D G + E ++ + GEY C
Sbjct: 3640 GATAVLRCELSKMAPVEWWKGHETLRDGDRHSLRQD---GARCELQIRGLVAEDAGEYLC 3696
Query: 88 VFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSED 147
+ E P + +E EG+TA L C+ PV W K
Sbjct: 3697 MCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLWCELSKAAPV---EWRK----GH 3749
Query: 148 KALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRS 204
+ L +G R + R EL I L + D G+Y C G ++ TL VR+
Sbjct: 3750 ETLRDG--DRHSLRQDGSRCELQIRGLAV-VDAGEYSC----VCGQERTSATLTVRA 3799
Score = 30.8 bits (68), Expect = 1.3
Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 9/84 (10%)
Query: 118 EGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNME 177
E ++ +L C P W YK D ++ SE +F +S +EL I L M
Sbjct: 2482 ELQSVVLSCDFRPAPKAVQW--YK-----DDTPLSPSE-KFKMSLEGQMAELRILRL-MP 2532
Query: 178 ADPGQYRCNGTSSKGSDQAIITLR 201
AD G YRC S+ S + + R
Sbjct: 2533 ADAGVYRCQAGSAHSSTEVTVEAR 2556
Score = 29.6 bits (65), Expect = 2.9
Identities = 32/133 (24%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 53 HRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKS 112
H + G + + PG+ F+V + G V LP+ + A PP+ A +S
Sbjct: 4573 HELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPES 4632
Query: 113 SEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIE 172
+ + GE L + E V + W+K ++ G F SQGR ++ +
Sbjct: 4633 RQ-VAAGEDVSL--ELEVVAEAGEVIWHK---GMERIQPGGR----FEVVSQGRQQMLVI 4682
Query: 173 NLNMEADPGQYRC 185
D G+Y C
Sbjct: 4683 KGFTAEDQGEYHC 4695
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 48.1 bits (113), Expect = 8e-06
Identities = 52/183 (28%), Positives = 79/183 (43%), Gaps = 32/183 (17%)
Query: 32 DLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTE-----------FKVDSDD 80
+ G+ +L+C + + TEVT W K G L + G + + K D+
Sbjct: 1087 EAGASAMLSCEVAQAQTEVT---WYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADA-- 1141
Query: 81 QWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEH----INEGETAMLVCKSESVPPVTD 136
GEYSC + + + ++ + P V A + S H G TAML C E P T+
Sbjct: 1142 --GEYSCEAGGQRV-SFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSC--EVAQPQTE 1196
Query: 137 WAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQA 196
WYK + K L + S+ R V R L ++ + +AD G+Y C + S Q
Sbjct: 1197 VTWYK----DGKKLSSSSKVRMEVKGCTRR--LVVQQVG-KADAGEYSCEAGGQRVSFQL 1249
Query: 197 IIT 199
IT
Sbjct: 1250 HIT 1252
Score = 39.7 bits (91), Expect = 0.003
Identities = 49/177 (27%), Positives = 75/177 (42%), Gaps = 23/177 (12%)
Query: 34 GSKILLTCSLNDSATEV--TGHRWLKGGV--VLKEDALPGQKTEFKVD--SDDQWGEYSC 87
G L C L+ +A GH L+ G L++D G + E ++ + GEYSC
Sbjct: 3728 GDTATLWCELSKAAPVEWRKGHETLRDGDRHSLRQD---GSRCELQIRGLAVVDAGEYSC 3784
Query: 88 VFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSED 147
V E P R ++ EG TA+L C+ PV W K +++
Sbjct: 3785 VCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAPV---EWRKGSET-- 3839
Query: 148 KALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRS 204
+ G + R+ + R EL I L++ AD G+Y C G ++ TL VR+
Sbjct: 3840 ---LRGGD-RYSLRQDGTRCELQIHGLSV-ADTGEYSC----VCGQERTSATLTVRA 3887
Score = 38.5 bits (88), Expect = 0.006
Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 27/188 (14%)
Query: 32 DLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDAL------PGQKTEFKVDS--DDQWG 83
+LG + L C + + V W K G ++ D P +DS G
Sbjct: 6026 ELGETVKLACRVTGTPKPVIS--WYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSG 6083
Query: 84 EYSCVFLPEPMGTAN----IQLHGPPR-VKAVKSSEHINEGETAMLVCKSESVPPVTDWA 138
+Y C F G + I + PPR V V++S + EGE A C E P
Sbjct: 6084 QYMC-FAASAAGNCSTLGKILVQVPPRFVNKVRASPFV-EGEDAQFTCTIEGAP-YPQIR 6140
Query: 139 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEA--DPGQYRCNGTSSKGSDQA 196
WYK D AL+ F + S+ RS L + + + D G Y C + GS +A
Sbjct: 6141 WYK-----DGALLTTGNK--FQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARA 6193
Query: 197 IITLRVRS 204
LR++S
Sbjct: 6194 SAELRIQS 6201
Score = 36.6 bits (83), Expect = 0.024
Identities = 38/121 (31%), Positives = 58/121 (47%), Gaps = 16/121 (13%)
Query: 83 GEYSCVFLPEPMGTANIQLHGPPR--VKAVKSSEHINEGETAMLVCKSESVPPVTDWAWY 140
GEY CV E +A + + P ++ VK+ E EG TA+L C+ S PV W
Sbjct: 3516 GEYLCVCGQERT-SATLTIRALPARFIEDVKNQE-AREGATAVLQCELNSAAPV---EWR 3570
Query: 141 KITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 200
K +++ L +G R+ + + EL I L M AD G+Y C + A++T+
Sbjct: 3571 KGSET----LRDG--DRYSLRQDGTKCELQIRGLAM-ADTGEYSC--VCGQERTSAMLTV 3621
Query: 201 R 201
R
Sbjct: 3622 R 3622
Score = 33.9 bits (76), Expect = 0.15
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 23/177 (12%)
Query: 34 GSKILLTCSLNDSATEV--TGHRWLKGGV--VLKEDALPGQKTEFKVDS--DDQWGEYSC 87
G+ +L C L+ A GH L+ G L++D G + E ++ + GEY C
Sbjct: 3640 GATAVLRCELSKMAPVEWWKGHETLRDGDRHSLRQD---GARCELQIRGLVAEDAGEYLC 3696
Query: 88 VFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSED 147
+ E P + +E EG+TA L C+ PV W K
Sbjct: 3697 MCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLWCELSKAAPV---EWRK----GH 3749
Query: 148 KALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRS 204
+ L +G R + R EL I L + D G+Y C G ++ TL VR+
Sbjct: 3750 ETLRDG--DRHSLRQDGSRCELQIRGLAV-VDAGEYSC----VCGQERTSATLTVRA 3799
Score = 30.8 bits (68), Expect = 1.3
Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 9/84 (10%)
Query: 118 EGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNME 177
E ++ +L C P W YK D ++ SE +F +S +EL I L M
Sbjct: 2482 ELQSVVLSCDFRPAPKAVQW--YK-----DDTPLSPSE-KFKMSLEGQMAELRILRL-MP 2532
Query: 178 ADPGQYRCNGTSSKGSDQAIITLR 201
AD G YRC S+ S + + R
Sbjct: 2533 ADAGVYRCQAGSAHSSTEVTVEAR 2556
Score = 29.6 bits (65), Expect = 2.9
Identities = 32/133 (24%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 53 HRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKS 112
H + G + + PG+ F+V + G V LP+ + A PP+ A +S
Sbjct: 4573 HELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPES 4632
Query: 113 SEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIE 172
+ + GE L + E V + W+K ++ G F SQGR ++ +
Sbjct: 4633 RQ-VAAGEDVSL--ELEVVAEAGEVIWHK---GMERIQPGGR----FEVVSQGRQQMLVI 4682
Query: 173 NLNMEADPGQYRC 185
D G+Y C
Sbjct: 4683 KGFTAEDQGEYHC 4695
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 46.2 bits (108), Expect = 3e-05
Identities = 30/124 (24%), Positives = 59/124 (47%), Gaps = 15/124 (12%)
Query: 83 GEYSCV---FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWA 138
G Y+C+ + + +H PPR+++ + +NE A+L C ++ +P P +W
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINW- 4202
Query: 139 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAII 198
+D L+ ++ +++ EL +EN+ +E D G Y C ++ G D +
Sbjct: 4203 ------KKDNVLLANLLGKY---TAEPYGELILENVVLE-DSGFYTCVANNAAGEDTHTV 4252
Query: 199 TLRV 202
+L V
Sbjct: 4253 SLTV 4256
Score = 42.0 bits (97), Expect = 6e-04
Identities = 29/99 (29%), Positives = 53/99 (53%), Gaps = 10/99 (10%)
Query: 104 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 163
PP +K S I ++ +L C +E VP +IT +D A++ G+ +R+ + +
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTP------RITWRKDGAVLAGNHARYSILEN 3765
Query: 164 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
LHI++ ++ D G+Y C T++ G+D+ I L+V
Sbjct: 3766 ---GFLHIQSAHV-TDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 41.6 bits (96), Expect = 7e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 13/116 (11%)
Query: 83 GEYSCVFLP---EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAW 139
G Y+CV + E +++++ PP + + + + + L+C+S+++PP T W
Sbjct: 2079 GRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPT-LTW 2137
Query: 140 YKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQ 195
K D G +S S+ RS L IE+ ++ D G+Y C T+ G +
Sbjct: 2138 LK--DGHPLLKKPG------LSISENRSVLKIEDAQVQ-DTGRYTCEATNVAGKTE 2184
Score = 41.6 bits (96), Expect = 7e-04
Identities = 46/187 (24%), Positives = 73/187 (39%), Gaps = 26/187 (13%)
Query: 30 VEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKE-DALP------GQKTEFKVDSDDQW 82
VE + + + LTC WLK ++ D+L G K +
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIA--WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDS 3219
Query: 83 GEYSCVFLPEPMGTAN----IQLHGPPRVKA--VKSSEHINEGETAMLVCKSESVP-PVT 135
G Y+C+ G A + + PP V + S + GE LVC + +P P+
Sbjct: 3220 GNYTCI-ASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLI 3278
Query: 136 DWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQ 195
W + K + +G R VS++ S L+I + +D G+Y C T+ G +
Sbjct: 3279 QWL------KDGKPIASGETERIRVSANG--STLNIYGA-LTSDTGKYTCVATNPAGEED 3329
Query: 196 AIITLRV 202
I L V
Sbjct: 3330 RIFNLNV 3336
Score = 41.2 bits (95), Expect = 0.001
Identities = 47/182 (25%), Positives = 75/182 (41%), Gaps = 32/182 (17%)
Query: 37 ILLTCSLNDSATEVTGHRWLKGGVVLKEDA----LPGQKTEFKVDSD-DQWGEYSCVFLP 91
I LTC + S WLK +K + +PG +T + + GEY+C+ +
Sbjct: 2982 ISLTCEV--SGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Query: 92 ---EPMGTANIQLHGPPRVKAVKSSE----HINEGETAMLVCKSESVPPVTDWAWYK--- 141
E ++ ++ PP +K S ++ EG + L C+S +VPP WYK
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV-ITWYKNGR 3098
Query: 142 -ITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 200
IT+S ++ + LHI+ + +D GQY C + G D L
Sbjct: 3099 MITESTHVEILADGQM------------LHIKKAEV-SDTGQYVCRAINVAGRDDKNFHL 3145
Query: 201 RV 202
V
Sbjct: 3146 NV 3147
Score = 39.7 bits (91), Expect = 0.003
Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 17/119 (14%)
Query: 83 GEYSCVF---LPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWA 138
G Y+CV E T ++ +H P + +N+GE L CK+ +P P W
Sbjct: 4235 GFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWT 4294
Query: 139 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAI 197
+ N + S G SEL IE ++ E D G Y C +S G +AI
Sbjct: 4295 F------------NNNIIPAHFDSVNGHSELVIERVSKE-DSGTYVCTAENSVGFVKAI 4340
Score = 38.1 bits (87), Expect = 0.008
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 83 GEYSCVFLP---EPMGTANIQLHGPPRVKAVKS--SEHINEGETAMLVCKSESVPPVTDW 137
G Y+CV E + +H PP ++ +E + L CK+ PV
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG-NPVPVI 1952
Query: 138 AWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAI 197
WYK D L++GS S F++ Q + IE+ + +D G Y+C +S G+ +
Sbjct: 1953 TWYK-----DNRLLSGSTSMTFLNRGQ---IIDIESAQI-SDAGIYKCVAINSAGATELF 2003
Query: 198 ITLRV 202
+L+V
Sbjct: 2004 YSLQV 2008
Score = 33.9 bits (76), Expect = 0.15
Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 12/106 (11%)
Query: 99 IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDSEDKALMNGSESR 157
+ +H PP+++ + G+ + C ++ P PV W+ L++G
Sbjct: 1165 LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWS-----KGGSTMLVDGEHH- 1218
Query: 158 FFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 203
VS+ G L I+ +D G Y C T+ G+D+ ITL V+
Sbjct: 1219 --VSNPDGT--LSIDQAT-PSDAGIYTCVATNIAGTDETEITLHVQ 1259
Score = 33.1 bits (74), Expect = 0.26
Identities = 41/157 (26%), Positives = 65/157 (41%), Gaps = 18/157 (11%)
Query: 55 WLKGGVVLKED-----ALPGQKTEFKVDSDDQWGEYSCVFLP---EPMGTANIQLHGPPR 106
WLK G ++ E L G+K G Y C+ + + +H PP
Sbjct: 1768 WLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPT 1827
Query: 107 VKAVKSSEHIN-EGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQG 165
+K+ SE + + + L C + +P + IT +D +N ++ + SS G
Sbjct: 1828 IKSSGLSERVVVKYKPVALQCIANGIPNPS------ITWLKDDQPVNTAQGNLKIQSS-G 1880
Query: 166 RSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
R L I +E D G+Y C T++ G Q I L V
Sbjct: 1881 RV-LQIAKTLLE-DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 32.7 bits (73), Expect = 0.34
Identities = 42/175 (24%), Positives = 71/175 (40%), Gaps = 18/175 (10%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVLKEDA----LPGQKTEFKVDSDDQWGEYSCVF 89
G + +LTC + + + V L E A L E K + GEY C+
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMV 593
Query: 90 LPEPMGTAN---IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSE 146
E +A + + PP+V + ++ G ++C + P KI +
Sbjct: 594 SSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP------KIAWTV 647
Query: 147 DKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLR 201
+ + GS R+ ++S L I+N + D G Y C ++S G+D+ TLR
Sbjct: 648 NDMFIVGSH-RYRMTSD---GTLFIKNAAPK-DAGIYGCLASNSAGTDKQNSTLR 697
Score = 31.2 bits (69), Expect = 0.99
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 83 GEYSCVFLPEPMGTA---NIQLHGPPRVKAV-KSSEHIN--EGETAMLVCKSESVPPVTD 136
G Y CV + T ++ +H PP + +S E+I+ E + L C++ +P +
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP-LPS 2417
Query: 137 WAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQA 196
W+K D +L N V G L + ME D GQY C ++ G ++
Sbjct: 2418 ITWFK--DGWPVSLSNS------VRILSGGRMLRLMQTTME-DAGQYTCVVRNAAGEERK 2468
Query: 197 IITLRV 202
I L V
Sbjct: 2469 IFGLSV 2474
Score = 30.8 bits (68), Expect = 1.3
Identities = 39/159 (24%), Positives = 65/159 (40%), Gaps = 22/159 (13%)
Query: 55 WLKGGVVLKEDALPGQKTEFKVD------SDDQWGEYSCVFLPEPMGTANIQ----LHGP 104
+++ GV L D + +D SD+ G Y C+ + GT Q + P
Sbjct: 463 FVRNGVTLGVDQYLKESASVNLDIAKVTLSDE--GFYECIAVSSA-GTGRAQTFFDVSEP 519
Query: 105 PRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQ 164
P V V ++ + GE A+L C S + W + + D L + R + S
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDY-NLTWQR--NDRDVRLAEPARIRTLANLS- 575
Query: 165 GRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 203
L ++++ D G+Y C +S GS A + L V+
Sbjct: 576 ----LELKSVKFN-DAGEYHCMVSSEGGSSAASVFLTVQ 609
Score = 30.0 bits (66), Expect = 2.2
Identities = 31/126 (24%), Positives = 47/126 (37%), Gaps = 18/126 (14%)
Query: 83 GEYSCVFLPEPMGTA---NIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWA 138
G Y CV + T ++Q+H P + + + L C++ +P P W
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW- 2045
Query: 139 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNME--ADPGQYRCNGTSSKGSDQA 196
L +GS F + Q S I L +D G+Y C ++ G Q
Sbjct: 2046 -----------LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094
Query: 197 IITLRV 202
I LRV
Sbjct: 2095 DIDLRV 2100
Score = 30.0 bits (66), Expect = 2.2
Identities = 41/180 (22%), Positives = 69/180 (38%), Gaps = 24/180 (13%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTE------FKVDSDDQWGEYSC 87
GS + C + T WL+ G L DA T K +++D G+Y+C
Sbjct: 3450 GSSTSMACITD--GTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDS-GKYTC 3506
Query: 88 VFLPEPMGTAN---IQLHGPPRVKAVKSSEHINE--GETAMLVCKSESVPPVTDWAWYKI 142
+ E + +++ PP + + E I+ L C + +P K+
Sbjct: 3507 IASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAP------KM 3560
Query: 143 TDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
T +D + ++ V + G L I +E D G+Y C +S G D +RV
Sbjct: 3561 TWMKDGRPLPQTDQ---VQTLGGGEVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRV 3616
Score = 29.6 bits (65), Expect = 2.9
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 23/177 (12%)
Query: 54 RWLKGGVVLKE------DALPGQKTEFKVDSDDQWGEYSCVFLPEP---MGTANIQLHGP 104
+W KG + L+ D L G + + D G+Y+CV + E G + + P
Sbjct: 734 KWFKGDLELRPSTFLIIDPLLGL-LKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP 792
Query: 105 PRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSS-S 163
P + + G L C + P T W ++ + M F VSS S
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTI-KWRRLDN------MPIFSRPFSVSSIS 845
Query: 164 QGRS-ELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEV 219
Q R+ L I NL +D G Y C + G Q+ T+ V +A P +GI V
Sbjct: 846 QLRTGALFILNL-WASDKGTYICEAENQFGKIQSETTVTVTGLVA---PLIGISPSV 898
Score = 28.1 bits (61), Expect = 8.4
Identities = 41/176 (23%), Positives = 63/176 (35%), Gaps = 24/176 (13%)
Query: 38 LLTCSLNDSATEVTGHRWLKGGVVLKEDA-----LPGQKTEFKVDSDDQWGEYSCVFLPE 92
++TC+ S W K G+ L L E + G Y+CV
Sbjct: 3915 VITCTA--SGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCV-ARN 3971
Query: 93 PMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDSED 147
G+A+ + +H PP ++ S H+ +L C++ P P W ++
Sbjct: 3972 AAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITW-------QKE 4024
Query: 148 KALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 203
+N S V S G L I E D G Y C + G+ I L V+
Sbjct: 4025 GINVNTSGRNHAVLPSGG---LQISRAVRE-DAGTYMCVAQNPAGTALGKIKLNVQ 4076
>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
Length = 1349
Score = 45.8 bits (107), Expect = 4e-05
Identities = 46/190 (24%), Positives = 82/190 (43%), Gaps = 19/190 (10%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVL----KEDALPGQKTEFKVDSDDQWGEYSC-- 87
G I +TC+ + + WLK G +L K G T V +D+ G Y+C
Sbjct: 154 GGSITMTCTAFGNPKPIV--TWLKEGTLLGASGKYQVSDGSLTVTSVSREDR-GAYTCRA 210
Query: 88 -VFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSE 146
E + T ++ + GPP + + + +N + A+L C++E+ P + WY E
Sbjct: 211 YSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWY--WQDE 268
Query: 147 DKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKG---SDQAIITLRVR 203
+ N + R + L I + E D G+Y C ++S G S A +T++
Sbjct: 269 NVYFQNDLKLRVRILID---GTLIIFRVKPE-DSGKYTCVPSNSLGRSPSASAYLTVQYP 324
Query: 204 SHLAALWPFL 213
+ + + P +
Sbjct: 325 ARVLNMPPVI 334
Score = 30.0 bits (66), Expect = 2.2
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 12/99 (12%)
Query: 2 AAALFVLLGFALLGTHGASGAAGTV------FTTV------EDLGSKILLTCSLNDSATE 49
A + + + LGT G S A V FT + ++ G ++L+ C+
Sbjct: 391 ALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFP 450
Query: 50 VTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCV 88
V R + K ALP +F+ S + GE+ CV
Sbjct: 451 VITWRKVGKPSRSKHSALPSGSLQFRALSKEDHGEWECV 489
>gi|13489095 sialoadhesin precursor [Homo sapiens]
Length = 1709
Score = 45.4 bits (106), Expect = 5e-05
Identities = 45/205 (21%), Positives = 80/205 (39%), Gaps = 17/205 (8%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEP 93
G ++L+C ++ E T +RW + G L+E F + Q G Y C +
Sbjct: 909 GQAVVLSCQVHTGVPEGTSYRWYRDGQPLQEST--SATLRFAAITLTQAGAYHC--QAQA 964
Query: 94 MGTANIQLHGPPRVKAVKSSEHI--------NEGETAMLVCKSESVPPVTDWAWY--KIT 143
G+A L P + + H+ G +L+C+ +S PP + ++
Sbjct: 965 PGSATTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLV 1024
Query: 144 DSEDKAL--MNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLR 201
S + + GS R V+ + L I +E D G Y C +++ G A
Sbjct: 1025 ASTLQGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLE-DEGVYICEASNTLGQASASADFD 1083
Query: 202 VRSHLAALWPFLGIVAEVLVLVTII 226
++ +WP + LV +T +
Sbjct: 1084 AQAVNVQVWPGATVREGQLVNLTCL 1108
Score = 36.6 bits (83), Expect = 0.024
Identities = 43/169 (25%), Positives = 62/169 (36%), Gaps = 28/169 (16%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEP 93
G + LTC +N S V+ +WLK GV L+ KT W +
Sbjct: 255 GELVTLTCQVNSSYPAVSSIKWLKDGVRLQ------TKTGVLHLPQAAWSDAGVYTCQAE 308
Query: 94 MGTAN-----IQLHGPPRVKAVKSSEHINEGETAMLVCKS-ESVPPVTDWAWYKITDSED 147
G + I LH V + I E +T LVC + P ++WYK +
Sbjct: 309 NGVGSLVSPPISLHIFMAEVQVSPAGPILENQTVTLVCNTPNEAPSDLRYSWYK-----N 363
Query: 148 KALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQA 196
L+ + S LH L AD G Y C + GS+++
Sbjct: 364 HVLLEDAHSHTL--------RLH---LATRADTGFYFCEVQNVHGSERS 401
Score = 35.8 bits (81), Expect = 0.040
Identities = 41/177 (23%), Positives = 69/177 (38%), Gaps = 9/177 (5%)
Query: 37 ILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSC----VFLPE 92
+ L C+ + A + W K V+L++ + +D G Y C V E
Sbjct: 342 VTLVCNTPNEAPSDLRYSWYKNHVLLEDAHSHTLRLHLATRADT--GFYFCEVQNVHGSE 399
Query: 93 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 152
G ++ ++ PP + + G +L C S P T + + +
Sbjct: 400 RSGPVSVVVNHPPLTPVLTAFLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDS 459
Query: 153 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAAL 209
RF +S L I +L E D G+Y+C+ T+S G+ A TL ++ A L
Sbjct: 460 DHSPRFSGTSGPNSLRLEIRDLE-ETDSGEYKCSATNSLGN--ATSTLDFHANAARL 513
Score = 33.9 bits (76), Expect = 0.15
Identities = 40/180 (22%), Positives = 70/180 (38%), Gaps = 17/180 (9%)
Query: 34 GSKILLTCSLN-DSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPE 92
G++ LTC+++ ++A W + GV+ + L T V D Y+C L E
Sbjct: 722 GTEANLTCNVSREAAGSPANFSWFRNGVLWAQGPLE-TVTLLPVARTDA-ALYACRILTE 779
Query: 93 PMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDK 148
+ + + PP + + + +G A+ +C +S P A + E
Sbjct: 780 AGAQLSTPVLLSVLYPPDRPKLSALLDMGQGHMALFICTVDSRP----LALLALFHGEHL 835
Query: 149 ALMN-----GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 203
+ S RF + +L + L + D G YRC T+ GS + +VR
Sbjct: 836 LATSLGPQVPSHGRFQAKAEANSLKLEVRELGL-GDSGSYRCEATNVLGSSNTSLFFQVR 894
>gi|166295173 kin of IRRE like [Homo sapiens]
Length = 757
Score = 45.1 bits (105), Expect = 7e-05
Identities = 59/215 (27%), Positives = 94/215 (43%), Gaps = 34/215 (15%)
Query: 29 TVEDLGSKILLTCS-LNDSATEVTGHRWLK--GGVVLKEDALPGQKTEFKVDSDDQWGEY 85
T D+GS + LTC + + +T W K +VL K+ + D+ G Y
Sbjct: 317 TTTDIGSDVTLTCVWVGNPPLTLT---WTKKDSNMVLSNSNQLLLKSVTQADA----GTY 369
Query: 86 SCVFLPEPMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTD--WAW 139
+C + +G A + ++GPP + + ++ ++ G+ + C S PP WAW
Sbjct: 370 TCRAIVPRIGVAEREVPLYVNGPPIISS-EAVQYAVRGDGGKVECFIGSTPPPDRIAWAW 428
Query: 140 YKITDSEDKALMNGSESRFFV----SSSQGRSELHIENLNMEAD-PGQYRCNGTSSKGSD 194
++ L G+ R+ V S S S L I N+ MEAD Y C +S G
Sbjct: 429 ------KENFLEVGTLERYTVERTNSGSGVLSTLTINNV-MEADFQTHYNCTAWNSFGPG 481
Query: 195 QAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIY 229
AII L R L +GI+A + +I+ I+
Sbjct: 482 TAIIQLEEREVLP-----VGIIAGATIGASILLIF 511
Score = 37.7 bits (86), Expect = 0.011
Identities = 42/161 (26%), Positives = 71/161 (44%), Gaps = 26/161 (16%)
Query: 29 TVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCV 88
TV++ G +++ TC + E+ G+RW KGG ++ EDA + E VD SC
Sbjct: 233 TVQE-GERVVFTCQATANP-EILGYRWAKGGFLI-EDA-HESRYETNVDYSFFTEPVSCE 288
Query: 89 FLPEPMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITD 144
+ +G+ N + +H PR+ + G L C PP+T W K
Sbjct: 289 -VHNKVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGSDVTLTCVWVGNPPLT-LTWTK--- 343
Query: 145 SEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRC 185
+S +S+S ++L ++++ +AD G Y C
Sbjct: 344 ---------KDSNMVLSNS---NQLLLKSVT-QADAGTYTC 371
Score = 31.2 bits (69), Expect = 0.99
Identities = 15/65 (23%), Positives = 28/65 (43%), Gaps = 4/65 (6%)
Query: 99 IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYK----ITDSEDKALMNGS 154
+ +H PP V + + EGE + C++ + P + + W K I D+ +
Sbjct: 217 LDVHHPPTVTLSIEPQTVQEGERVVFTCQATANPEILGYRWAKGGFLIEDAHESRYETNV 276
Query: 155 ESRFF 159
+ FF
Sbjct: 277 DYSFF 281
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 44.7 bits (104), Expect = 9e-05
Identities = 38/125 (30%), Positives = 51/125 (40%), Gaps = 19/125 (15%)
Query: 83 GEYSC-VFLPEPMGTANIQLH--GPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAW 139
G+Y C P A I LH PP V + GET L C + PP+T + W
Sbjct: 3274 GQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLT-FQW 3332
Query: 140 YKITDSEDKALMNGSESRFFVSSSQGRSE-LHIENLNMEADPGQYRCNGTSSKGSDQAII 198
++ S + R+E LH E E D G+YRC T+ GS +A
Sbjct: 3333 SRVGSS-------------LPGRATARNELLHFERAAPE-DSGRYRCRVTNKVGSAEAFA 3378
Query: 199 TLRVR 203
L V+
Sbjct: 3379 QLLVQ 3383
Score = 35.0 bits (79), Expect = 0.069
Identities = 49/206 (23%), Positives = 89/206 (43%), Gaps = 32/206 (15%)
Query: 12 ALLGTHGASGAAGTVFTT----VEDLGSKILLTCSL-NDSATEVTGHRWLKGGVVLKEDA 66
+L T +G+ TV T + +G+ + C++ +D T++ RW K G L
Sbjct: 3388 SLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQL---RWFKEGGQLP--- 3441
Query: 67 LPGQKTE---FKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAM 123
PG + ++ + DQ SC GT Q HGP KA S++ + + ++
Sbjct: 3442 -PGHSVQDGVLRIQNLDQ----SC------QGTYICQAHGPWG-KAQASAQLVIQALPSV 3489
Query: 124 LVCKSESVPPVT-----DWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEA 178
L+ SV V ++ + D + + + Q + I ++ + A
Sbjct: 3490 LINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGGVVRIAHVEL-A 3548
Query: 179 DPGQYRCNGTSSKGSDQAIITLRVRS 204
D GQYRC T++ G+ Q+ + L V++
Sbjct: 3549 DAGQYRCTATNAAGTTQSHVLLLVQA 3574
Score = 34.7 bits (78), Expect = 0.090
Identities = 36/137 (26%), Positives = 52/137 (37%), Gaps = 35/137 (25%)
Query: 83 GEYSCVFLPEPMGTANIQLH----------GPPRVKAVKSSEHINEGETAMLVCKSESVP 132
G Y C+ +GTA Q+ G P+V+A ++ + G TA L C + P
Sbjct: 3181 GTYVCL-AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSP 3239
Query: 133 -PVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNM----EADPGQYRCNG 187
P W+ + S + L + L + + D GQY CN
Sbjct: 3240 APTIHWSKLR-------------------SPLPWQHRLEGDTLIIPRVAQQDSGQYICNA 3280
Query: 188 TSSKGSDQAIITLRVRS 204
TS G +A I L V S
Sbjct: 3281 TSPAGHAEATIILHVES 3297
Score = 32.3 bits (72), Expect = 0.44
Identities = 38/132 (28%), Positives = 50/132 (37%), Gaps = 30/132 (22%)
Query: 83 GEYSCVFLPEPMGTANIQLH---------GPPRVKAVKSSEHINEGETAMLVC--KSESV 131
G Y CV P GTA ++ PP VK SS + EG+T L C +
Sbjct: 2021 GFYLCV-ATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAH 2079
Query: 132 PPVTDWAWYKITDS-EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSS 190
VT WY+ S ++GS R S AD G+Y C +
Sbjct: 2080 AQVT---WYRRGGSLPPHTQVHGSRLRLPQVS--------------PADSGEYVCRVENG 2122
Query: 191 KGSDQAIITLRV 202
G +A IT+ V
Sbjct: 2123 SGPKEASITVSV 2134
Score = 32.0 bits (71), Expect = 0.58
Identities = 50/181 (27%), Positives = 69/181 (38%), Gaps = 39/181 (21%)
Query: 34 GSKILLTCSLNDSA-TEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSC----- 87
G + L C + A +VT H+ +GG + + G S GEYSC
Sbjct: 2841 GQTLDLKCVVPGQAHAQVTWHK--RGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGS 2898
Query: 88 --------VFLPEPMGTANIQLHG---PPRVKAVKSSEHINEGETAMLVC--KSESVPPV 134
+ EP I G P ++A SS H+ EG+T L C ++ V
Sbjct: 2899 SGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEA--SSSHVTEGQTLDLNCVVPGQAHAQV 2956
Query: 135 TDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 194
T WYK S +R SQ R LH+ + AD G+Y C S G +
Sbjct: 2957 T---WYKRGGS--------LPARHQTHGSQLR--LHLVS---PADSGEYVCRAASGPGPE 3000
Query: 195 Q 195
Q
Sbjct: 3001 Q 3001
Score = 31.6 bits (70), Expect = 0.76
Identities = 46/194 (23%), Positives = 70/194 (36%), Gaps = 43/194 (22%)
Query: 34 GSKILLTCSL-NDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLP- 91
G + L C + S +VT H+ +GG + G S GEY C L
Sbjct: 2355 GQTLDLNCVVPGQSHAQVTWHK--RGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGS 2412
Query: 92 ------------EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVC--KSESVPPVTDW 137
EP G+ L P V+ SS + EG+T L C ++ VT
Sbjct: 2413 SVPLEASVLVTIEPAGSVPA-LGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVT-- 2469
Query: 138 AWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNM----EADPGQYRCNGTSSKGS 193
W+K S R ++H L + AD G+Y C S G+
Sbjct: 2470 -WHKRG-----------------GSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGT 2511
Query: 194 DQAIITLRVRSHLA 207
+A + + ++ L+
Sbjct: 2512 QEASVLVTIQQRLS 2525
Score = 30.8 bits (68), Expect = 1.3
Identities = 31/102 (30%), Positives = 40/102 (39%), Gaps = 11/102 (10%)
Query: 103 GPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSS 162
G PRV+ ++ G T L C++ VP T W K GS S
Sbjct: 1954 GGPRVQVSPERTQVHAGRTVRLYCRAAGVPSAT-ITWRK---------EGGSLPPQARSE 2003
Query: 163 SQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRS 204
+ L I + AD G Y C TS G+ QA I + V S
Sbjct: 2004 RTDIATLLIPAIT-TADAGFYLCVATSPAGTAQARIQVVVLS 2044
Score = 30.0 bits (66), Expect = 2.2
Identities = 44/207 (21%), Positives = 74/207 (35%), Gaps = 37/207 (17%)
Query: 34 GSKILLTCSLNDSA-TEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLP- 91
G + L C + A +VT H+ +GG + G + S GEY C +
Sbjct: 2741 GETLDLNCVVPGQAHAQVTWHK--RGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGS 2798
Query: 92 ------------EPMGTANIQLHGP---PRVKAVKSSEHINEGETAMLVC--KSESVPPV 134
E G++ + + P P ++ SS + EG+T L C ++ V
Sbjct: 2799 SGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQV 2858
Query: 135 TDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 194
T W+K + + Q L N AD G+Y C T S G+
Sbjct: 2859 T---WHKRGGN-------------LPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTL 2902
Query: 195 QAIITLRVRSHLAALWPFLGIVAEVLV 221
+A + + + P G+ + +
Sbjct: 2903 EASVLVTIEPSSPGPIPAPGLAQPIYI 2929
Score = 28.9 bits (63), Expect = 4.9
Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 12/92 (13%)
Query: 113 SEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIE 172
S+ + G +C ++S P W + L NG + + L I
Sbjct: 1780 SQSVRPGADVTFICTAKSKSPAYTLVWTR--------LHNG---KLPTRAMDFNGILTIR 1828
Query: 173 NLNMEADPGQYRCNGTSSKGSDQAIITLRVRS 204
N+ + +D G Y C G++ DQ TL V++
Sbjct: 1829 NVQL-SDAGTYVCTGSNMFAMDQGTATLHVQA 1859
>gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
Length = 338
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/126 (29%), Positives = 63/126 (50%), Gaps = 14/126 (11%)
Query: 80 DQWGEYSCVFLPE----PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVT 135
DQ GEY C L + + I ++ PP + K++ ++ G+ +L C++ +VP +
Sbjct: 188 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTG-VSVGQKGILSCEASAVP-MA 245
Query: 136 DWAWYKITDSEDKALMNGSESRFFVSSSQGR-SELHIENLNMEADPGQYRCNGTSSKGSD 194
++ W+K E+ L G + ++GR S L N++ E D G Y C T+ G+
Sbjct: 246 EFQWFK----EETRLATGLDGMRI--ENKGRMSTLTFFNVS-EKDYGNYTCVATNKLGNT 298
Query: 195 QAIITL 200
A ITL
Sbjct: 299 NASITL 304
Score = 31.2 bits (69), Expect = 0.99
Identities = 40/173 (23%), Positives = 66/173 (38%), Gaps = 39/173 (22%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVL-----------KEDALPGQKTEFK-----VD 77
G L C+++D T V WL +L + L T++ VD
Sbjct: 43 GESATLRCTIDDRVTRVA---WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVD 99
Query: 78 SDDQWGEYSC-VFLPEPMGTANIQL--HGPPRVKAVKSSEHINEGETAMLVCKSESVP-P 133
D+ G Y+C V T+ + L PP++ + S +NEG + L+C + P P
Sbjct: 100 VYDE-GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEP 158
Query: 134 VTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCN 186
W + E + FVS + L I ++ + G+Y C+
Sbjct: 159 TVTWRHLSV-----------KEGQGFVSEDE---YLEISDIKRD-QSGEYECS 196
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/126 (29%), Positives = 63/126 (50%), Gaps = 14/126 (11%)
Query: 80 DQWGEYSCVFLPE----PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVT 135
DQ GEY C L + + I ++ PP + K++ ++ G+ +L C++ +VP +
Sbjct: 195 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTG-VSVGQKGILSCEASAVP-MA 252
Query: 136 DWAWYKITDSEDKALMNGSESRFFVSSSQGR-SELHIENLNMEADPGQYRCNGTSSKGSD 194
++ W+K E+ L G + ++GR S L N++ E D G Y C T+ G+
Sbjct: 253 EFQWFK----EETRLATGLDGMRI--ENKGRMSTLTFFNVS-EKDYGNYTCVATNKLGNT 305
Query: 195 QAIITL 200
A ITL
Sbjct: 306 NASITL 311
Score = 31.2 bits (69), Expect = 0.99
Identities = 40/173 (23%), Positives = 66/173 (38%), Gaps = 39/173 (22%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVL-----------KEDALPGQKTEFK-----VD 77
G L C+++D T V WL +L + L T++ VD
Sbjct: 50 GESATLRCTIDDRVTRVA---WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVD 106
Query: 78 SDDQWGEYSC-VFLPEPMGTANIQL--HGPPRVKAVKSSEHINEGETAMLVCKSESVP-P 133
D+ G Y+C V T+ + L PP++ + S +NEG + L+C + P P
Sbjct: 107 VYDE-GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEP 165
Query: 134 VTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCN 186
W + E + FVS + L I ++ + G+Y C+
Sbjct: 166 TVTWRHLSV-----------KEGQGFVSEDE---YLEISDIKRD-QSGEYECS 203
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 43.9 bits (102), Expect = 1e-04
Identities = 45/182 (24%), Positives = 78/182 (42%), Gaps = 17/182 (9%)
Query: 33 LGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALP--GQKTEFKVDSDDQW---GEYSC 87
+GS ++L+C+L S E T + +VL ++A+ G E + + Q G Y C
Sbjct: 388 IGSTVILSCALTGSP-EFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQC 446
Query: 88 VFLPEPMGTANIQL----HGPPRVKAVKSSEHINEGETAMLVCKSESVPPVT-DWAWYKI 142
+ + + G PR+ + S + +N GE L+C ++ PP T WA
Sbjct: 447 FATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWAL--- 503
Query: 143 TDSEDKALMNGSESRFFVSSSQGRSELHIENLNME-ADPGQYRCNGTSSKGSDQAIITLR 201
++ + +GS + S G + H+ + D G YRC + GS + +
Sbjct: 504 --DDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARIN 561
Query: 202 VR 203
VR
Sbjct: 562 VR 563
Score = 28.1 bits (61), Expect = 8.4
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%)
Query: 124 LVCKSESVP-PVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ 182
L C S P P W DSED A+ + + ++ L + + E D G
Sbjct: 1369 LPCNSVGDPAPAVKWT----KDSEDSAIPVSMDGHRLIHTN---GTLLLRAVKAE-DSGY 1420
Query: 183 YRCNGTSSKGSDQAIITLRVR 203
Y C T++ G D I+ L V+
Sbjct: 1421 YTCTATNTGGFDTIIVNLLVQ 1441
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 43.5 bits (101), Expect = 2e-04
Identities = 34/134 (25%), Positives = 65/134 (48%), Gaps = 22/134 (16%)
Query: 73 EFKVDSDDQWGEYSC---VFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSE 129
+F ++ + G SC V + EP ++ PP V+ +K++E L C+
Sbjct: 5493 DFICEAQNPAGSTSCSTKVIVKEPPVFSSF----PPIVETLKNAE-------VSLECELS 5541
Query: 130 SVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTS 189
PP + WYK DK + S+ ++ ++S + +HI N++ +D G+Y C +
Sbjct: 5542 GTPPF-EVVWYK-----DKRQLRSSK-KYKIASKNFHTSIHILNVDT-SDIGEYHCKAQN 5593
Query: 190 SKGSDQAIITLRVR 203
GSD + T++++
Sbjct: 5594 EVGSDTCVCTVKLK 5607
Score = 41.6 bits (96), Expect = 7e-04
Identities = 38/153 (24%), Positives = 68/153 (44%), Gaps = 21/153 (13%)
Query: 54 RWLKGGVVL--------KEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMG---TANIQLH 102
RW KG L ++AL + V + D G Y+C G +AN+ +
Sbjct: 4238 RWFKGNKELVSGGSCYITKEALESSLELYLVKTSDS-GTYTCKVSNVAGGVECSANLFVK 4296
Query: 103 GPPR-VKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVS 161
P V+ ++ S+ + +G+ L CK PP+ W+ + D+ + S+ R +S
Sbjct: 4297 EPATFVEKLEPSQLLKKGDATQLACKVTGTPPI-KITWF----ANDREIKESSKHR--MS 4349
Query: 162 SSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 194
+ + L + ++ +E D G+Y C + GSD
Sbjct: 4350 FVESTAVLRLTDVGIE-DSGEYMCEAQNEAGSD 4381
Score = 40.0 bits (92), Expect = 0.002
Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 13/136 (9%)
Query: 72 TEFKVDSDDQWGEYSCV---FLPEPMGTANIQLHGPPR-VKAVKSSEHINEGETAMLVCK 127
T KV D G+Y+C + +A + + PPR +K ++ S + + E CK
Sbjct: 7270 TVLKVGKGDA-GQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECK 7328
Query: 128 SESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNG 187
P + WYK ++ + S+ R S E+H NL++E D G Y C
Sbjct: 7329 IGGSPEIKV-LWYK----DETEIQESSKFRMSFVDSVAVLEMH--NLSVE-DSGDYTCEA 7380
Query: 188 TSSKGSDQAIITLRVR 203
++ GS + +L+V+
Sbjct: 7381 HNAAGSASSSTSLKVK 7396
Score = 39.3 bits (90), Expect = 0.004
Identities = 51/191 (26%), Positives = 78/191 (40%), Gaps = 33/191 (17%)
Query: 31 EDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKED-----ALPGQKTEFKVDSDD--QWG 83
+ +G + LTC LN SA W + GV+L++D + K+ D G
Sbjct: 6186 QTVGLPVTLTCRLNGSAPIQVC--WYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSG 6243
Query: 84 EYSCVFLPEPMGTANIQLHGPPR---------VKAVKSSEHINEGETAMLVCKSESVPPV 134
+YSC P+GTA+ R +K V S + GE+A C P+
Sbjct: 6244 QYSCS-ASNPLGTASSSARLTAREPKKSPFFDIKPV--SIDVIAGESADFECHVTGAQPM 6300
Query: 135 TDWAWYKITDSED-KALMNGSESRFFVSSSQGRSELHIENLNM-EADPGQYRCNGTSSKG 192
+IT S+D K + G + + G + H+ L + + D GQY C T+ G
Sbjct: 6301 ------RITWSKDNKEIRPGGN---YTITCVGNTP-HLRILKVGKGDSGQYTCQATNDVG 6350
Query: 193 SDQAIITLRVR 203
D L V+
Sbjct: 6351 KDMCSAQLSVK 6361
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/125 (22%), Positives = 59/125 (47%), Gaps = 11/125 (8%)
Query: 83 GEYSCVF---LPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAW 139
G+Y+C + ++++ PP + +G L C+ + PP +W
Sbjct: 7374 GDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPF-HVSW 7432
Query: 140 YKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIIT 199
YK + + L +G ++ + S + +HI N++ AD G+Y+C T+ GSD + +
Sbjct: 7433 YK----DKRELRSGK--KYKIMSENFLTSIHILNVDA-ADIGEYQCKATNDVGSDTCVGS 7485
Query: 200 LRVRS 204
+ +++
Sbjct: 7486 IALKA 7490
Score = 38.1 bits (87), Expect = 0.008
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 35/180 (19%)
Query: 33 LGSKILLTCSLN-DSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQW--------- 82
+ K+ L C ++ D VT W K G L PG+ ++K+ +D+
Sbjct: 3657 INKKVHLECQVDEDRKVTVT---WSKDGQKLP----PGK--DYKICFEDKIATLEIPLAK 3707
Query: 83 ----GEYSCVFLPEPMGT---ANIQLHGPPR-VKAVKSSEHINEGETAMLVCKSESVPPV 134
G Y C E + A + + PP VK V S + GE+A L CK + PV
Sbjct: 3708 LKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKG-SPV 3766
Query: 135 TDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 194
W+K +K L + R + +S+ + L I ++ +E D G Y C + GSD
Sbjct: 3767 IQVTWFK----NNKELSESNTVRMYFVNSE--AILDITDVKVE-DSGSYSCEAVNDVGSD 3819
Score = 38.1 bits (87), Expect = 0.008
Identities = 49/191 (25%), Positives = 76/191 (39%), Gaps = 33/191 (17%)
Query: 31 EDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEF-------KVDSDDQ-- 81
E LG + C +N S E W K GV+LK+DA +T F ++ DQ
Sbjct: 7127 ETLGFPVAFECRINGS--EPLQVSWYKDGVLLKDDA--NLQTSFVHNVATLQILQTDQSH 7182
Query: 82 WGEYSCVFLPEPMGTAN-------IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPV 134
G+Y+C P+GTA+ + PP S + GE+ C P+
Sbjct: 7183 IGQYNC-SASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPI 7241
Query: 135 TDWAWYKITDSEDKALM--NGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKG 192
KIT ++D + G+ V ++ + L + + D GQY C ++ G
Sbjct: 7242 ------KITWAKDNREIRPGGNYKMTLVENTATLTVLKVG----KGDAGQYTCYASNIAG 7291
Query: 193 SDQAIITLRVR 203
D L V+
Sbjct: 7292 KDSCSAQLGVQ 7302
Score = 37.7 bits (86), Expect = 0.011
Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 99 IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRF 158
+ + PP S +G +L C+ PP + W K D+ + S+ +F
Sbjct: 6452 LTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPF-EVVWVK-----DRKQVRNSK-KF 6504
Query: 159 FVSSSQGRSELHIENLNMEA-DPGQYRCNGTSSKGSDQAIITLRVR 203
++S + LHI LN+EA D G+Y C T+ GSD +++ +
Sbjct: 6505 KITSKHFDTSLHI--LNLEASDVGEYHCKATNEVGSDTCSCSVKFK 6548
Score = 36.6 bits (83), Expect = 0.024
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 104 PPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDSEDKALMNGSESRFFVSS 162
PP+++A+ S I+EG+ + C P P W+ + + + + RF + +
Sbjct: 33328 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWS------CGGRKIHSQEQGRFHIEN 33381
Query: 163 SQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRS 204
+ + L I ++ + D G Y + + GSD A + + +RS
Sbjct: 33382 TDDLTTLIIMDVQKQ-DGGLYTLSLGNEFGSDSATVNIHIRS 33422
Score = 36.2 bits (82), Expect = 0.031
Identities = 43/194 (22%), Positives = 74/194 (38%), Gaps = 33/194 (17%)
Query: 31 EDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEF----------KVDSDD 80
E +G ++ C++ S +E W K G LK+ P +T F K D
Sbjct: 8068 ETVGLPVVFDCAI--SGSEPISVSWYKDGKPLKDS--PNVQTSFLDNTATLNIFKTDRSL 8123
Query: 81 QWGEYSCVFLPEPMGTANIQLH-------GPPRVKAVKSSEHINEGETAMLVCKSESVPP 133
G+YSC P+G+A+ PP + GE+A C P
Sbjct: 8124 A-GQYSCT-ATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQP 8181
Query: 134 V-TDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKG 192
+ WA + + + +G ++ +S + + L + ++ + D GQY C + G
Sbjct: 8182 IKVSWA------KDSREIRSGG--KYQISYLENSAHLTVLKVD-KGDSGQYTCYAVNEVG 8232
Query: 193 SDQAIITLRVRSHL 206
D L ++ L
Sbjct: 8233 KDSCTAQLNIKERL 8246
Score = 33.5 bits (75), Expect = 0.20
Identities = 45/187 (24%), Positives = 78/187 (41%), Gaps = 31/187 (16%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVLKED---------ALPGQKTEFKVDSDDQWGE 84
G L C++ + T +W K G L D + G K SD G
Sbjct: 7600 GDTCTLECTV--AGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDS--GV 7655
Query: 85 YSCVFLPEPMG----TANIQLHG----PPRVKAVKSSEHINEGETAMLVCKSESVPPVTD 136
YS + P+G TA++Q+ P + +K + ++ G + ++ CK PP++
Sbjct: 7656 YSFE-VQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS-GSSVVMECKVYGSPPISV 7713
Query: 137 WAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQA 196
+W+ E + +G ++ + + L + N+ E+D G Y C T+ GSD+
Sbjct: 7714 -SWFH----EGNEISSGR--KYQTTLTDNTCALTV-NMLEESDSGDYTCIATNMAGSDEC 7765
Query: 197 IITLRVR 203
L VR
Sbjct: 7766 SAPLTVR 7772
Score = 32.3 bits (72), Expect = 0.44
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 13/134 (9%)
Query: 75 KVDSDDQWGEYSCVF---LPEPMGTANIQLHGPPR-VKAVKSSEHINEGETAMLVCKSES 130
KV D G+Y+C + + M +A + + PP+ VK +++S+ +GE+ L CK
Sbjct: 6332 KVGKGDS-GQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISG 6390
Query: 131 VPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSS 190
P + +W++ DSE ++ +S + L I + E D G Y C +
Sbjct: 6391 SPEI-KVSWFR-NDSE-----LHESWKYNMSFINSVALLTINEASAE-DSGDYICEAHNG 6442
Query: 191 KGSDQAIITLRVRS 204
G L V++
Sbjct: 6443 VGDASCSTALTVKA 6456
Score = 32.3 bits (72), Expect = 0.44
Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 8/107 (7%)
Query: 96 TANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSE 155
T + +L P + S++INEG+ + C+ S P + W+K L
Sbjct: 33125 TLSKELSDAPAFISQPRSQNINEGQNVLFTCEI-SGEPSPEIEWFK------NNLPISIS 33177
Query: 156 SRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
S +S S+ L I N ++ +D G+Y + +G A +L V
Sbjct: 33178 SNVSISRSRNVYSLEIRNASV-SDSGKYTIKAKNFRGQCSATASLMV 33223
Score = 30.8 bits (68), Expect = 1.3
Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 15/90 (16%)
Query: 118 EGETAMLVCKSESVPPVTDWAWY----KITDSEDKALMNGSESRFFVSSSQGRSELHIEN 173
EG VCK E+ T WY ++ +SE ++ ++ G + L++++
Sbjct: 31581 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSE----------KYEITYEDGVAILYVKD 31630
Query: 174 LNMEADPGQYRCNGTSSKGSDQAIITLRVR 203
+ + D G YRC + G D + L V+
Sbjct: 31631 IT-KLDDGTYRCKVVNDYGEDSSYAELFVK 31659
Score = 30.0 bits (66), Expect = 2.2
Identities = 37/153 (24%), Positives = 58/153 (37%), Gaps = 19/153 (12%)
Query: 45 DSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTA-----NI 99
DSA + + +K L + EF+V ++++ G L P TA +
Sbjct: 30474 DSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETG------LSRPRRTAMSIKTKL 30527
Query: 100 QLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFF 159
P ++ GE A L C+ P+ D WY+ K L+ +SR +
Sbjct: 30528 TSGEAPGIRKEMKDVTTKLGEAAQLSCQIVG-RPLPDIKWYRF----GKELI---QSRKY 30579
Query: 160 VSSSQGRSELHIENLNMEADPGQYRCNGTSSKG 192
SS GR+ + D G Y C T+ G
Sbjct: 30580 KMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG 30612
Score = 29.6 bits (65), Expect = 2.9
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 23/129 (17%)
Query: 83 GEYSCVFLPEP----MGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWA 138
GEY C E + I P K K E + E + ML+ + PP +
Sbjct: 4368 GEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDV-MLLAEVAGTPPF-EIT 4425
Query: 139 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNM----EADPGQYRCNGTSSKGSD 194
W+K ++ L +G + + F+ H+ +L + AD G+Y+C T+ GS
Sbjct: 4426 WFK----DNTILRSGRKYKTFIQD-------HLVSLQILKFVAADAGEYQCRVTNEVGSS 4474
Query: 195 --QAIITLR 201
A +TLR
Sbjct: 4475 ICSARVTLR 4483
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 42.7 bits (99), Expect = 3e-04
Identities = 49/181 (27%), Positives = 79/181 (43%), Gaps = 34/181 (18%)
Query: 80 DQWGEYSCVFLPEPMG---TANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVT 135
+ G YSC+ G A++ + P + + GETA+L C + P P
Sbjct: 668 EDMGIYSCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRL 727
Query: 136 DWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQ 195
+W ++D + +E FF +++Q L I + +E D G+Y C +++ G+++
Sbjct: 728 NW-------TKDDGPLLVTERHFFAAANQ---LLIIVDAGLE-DAGKYTCIMSNTLGTER 776
Query: 196 AIITLRVRS------------HLAALWPFLGIVAEVLV-------LVTIIFIYEKRRKPE 236
I L V S H W +GIV V+V L+ +I IY RRK E
Sbjct: 777 GHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNE 836
Query: 237 D 237
D
Sbjct: 837 D 837
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 42.7 bits (99), Expect = 3e-04
Identities = 57/202 (28%), Positives = 78/202 (38%), Gaps = 42/202 (20%)
Query: 34 GSKILLTCSLNDSATEVTGHRWLKGGVVLK-------EDALPGQKT-------EFKVDSD 79
G + LTC + S RW K +K EDA +KT +F+VD
Sbjct: 141 GDLMQLTCKTSGSKP-AADIRWFKNDKEIKDVKYLKEEDA--NRKTFTVSSTLDFRVDRS 197
Query: 80 DQWGEYSCVFLPEPMGTAN------IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPP 133
D C E + +++H P VK + S+ EG+ +L C+S+ P
Sbjct: 198 DDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPL 257
Query: 134 VTDWAWYKITDSEDKALMNGSE----SRFFVSSSQGRSELHIENLNMEADPGQYRCNGTS 189
W K +G E R VS GR EL+I LN + D G YRC T+
Sbjct: 258 PEPVLWTK----------DGGELPDPDRMVVS---GR-ELNILFLN-KTDNGTYRCEATN 302
Query: 190 SKGSDQAIITLRVRSHLAALWP 211
+ G A L V L P
Sbjct: 303 TIGQSSAEYVLIVHDVPNTLLP 324
Score = 33.9 bits (76), Expect = 0.15
Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 4/69 (5%)
Query: 83 GEYSCVFLPEPMGTANIQLH--GPPRVKAVKS-SEHINEGETAMLVCKSESVPPVTDWAW 139
G+Y+C P+ T+ L G P + S + EG+ L CK+ P D W
Sbjct: 102 GQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRW 161
Query: 140 YKITDSEDK 148
+K D E K
Sbjct: 162 FK-NDKEIK 169
>gi|236464356 neuregulin 1 isoform HRG-gamma3 [Homo sapiens]
Length = 177
Score = 41.6 bits (96), Expect = 7e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 104 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 163
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 164 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
>gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens]
Length = 207
Score = 41.6 bits (96), Expect = 7e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 104 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 163
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 164 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
>gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens]
Length = 459
Score = 41.6 bits (96), Expect = 7e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 104 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 163
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 164 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 202
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,676,194
Number of Sequences: 37866
Number of extensions: 468705
Number of successful extensions: 1327
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 137
Number of HSP's that attempted gapping in prelim test: 1021
Number of HSP's gapped (non-prelim): 375
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.