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Search of human proteins with 38327562
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38327562 serine/threonine protein kinase 6 [Homo sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38327572 serine/threonine protein kinase 6 [Homo sapiens] 817 0.0
gi|38327570 serine/threonine protein kinase 6 [Homo sapiens] 817 0.0
gi|38327568 serine/threonine protein kinase 6 [Homo sapiens] 817 0.0
gi|38327566 serine/threonine protein kinase 6 [Homo sapiens] 817 0.0
gi|38327564 serine/threonine protein kinase 6 [Homo sapiens] 817 0.0
gi|38327562 serine/threonine protein kinase 6 [Homo sapiens] 817 0.0
gi|83776600 aurora kinase B [Homo sapiens] 406 e-113
gi|62865639 aurora kinase C isoform 1 [Homo sapiens] 398 e-111
gi|62865641 aurora kinase C isoform 2 [Homo sapiens] 397 e-110
gi|62865643 aurora kinase C isoform 3 [Homo sapiens] 396 e-110
gi|121114283 polo-like kinase 4 [Homo sapiens] 199 5e-51
gi|156105707 SNF related kinase [Homo sapiens] 173 3e-43
gi|156105705 SNF related kinase [Homo sapiens] 173 3e-43
gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform... 171 1e-42
gi|193083129 MAP/microtubule affinity-regulating kinase 3 isofor... 171 1e-42
gi|193083127 MAP/microtubule affinity-regulating kinase 3 isofor... 171 1e-42
gi|193083125 MAP/microtubule affinity-regulating kinase 3 isofor... 171 1e-42
gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform... 171 1e-42
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s... 171 1e-42
gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent ... 170 2e-42
gi|150456432 unc-51-like kinase 3 [Homo sapiens] 169 3e-42
gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens] 169 5e-42
gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [H... 169 5e-42
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor... 168 9e-42
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor... 168 9e-42
gi|254028234 MAP/microtubule affinity-regulating kinase 2 isofor... 168 9e-42
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor... 168 9e-42
gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo ... 167 1e-41
gi|38569460 SNF1-like kinase 2 [Homo sapiens] 166 3e-41
gi|4826948 protein kinase, X-linked [Homo sapiens] 166 3e-41
>gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 817 bits (2110), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
Query: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 817 bits (2110), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
Query: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>gi|38327568 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 817 bits (2110), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
Query: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>gi|38327566 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 817 bits (2110), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
Query: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>gi|38327564 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 817 bits (2110), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
Query: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>gi|38327562 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 817 bits (2110), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1 MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
Query: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61 AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>gi|83776600 aurora kinase B [Homo sapiens]
Length = 344
Score = 406 bits (1044), Expect = e-113
Identities = 192/264 (72%), Positives = 224/264 (84%)
Query: 126 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQ 185
R + ++DFEIGRPLGKGKFGNVYLAREK+S FI+ALKVLFK+Q+EK GVEHQLRRE+EIQ
Sbjct: 70 RHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQ 129
Query: 186 SHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
+HL HPNILRLY YF+D R+YLILEYAP G +Y+ELQK FDEQRTAT + ELA+AL
Sbjct: 130 AHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALM 189
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRM 305
YCH K+VIHRDIKPENLLLG GELKIADFGWSVHAPS RR T+CGTLDYLPPEMIEGRM
Sbjct: 190 YCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRM 249
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
H+EKVDLW +GVLCYE LVG PPFE+ ++ ETY+RI +V+ FP V GA+DLIS+LL+
Sbjct: 250 HNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLR 309
Query: 366 HNPSQRPMLREVLEHPWITANSSK 389
HNPS+R L +V HPW+ ANS +
Sbjct: 310 HNPSERLPLAQVSAHPWVRANSRR 333
>gi|62865639 aurora kinase C isoform 1 [Homo sapiens]
Length = 309
Score = 398 bits (1022), Expect = e-111
Identities = 192/282 (68%), Positives = 231/282 (81%), Gaps = 4/282 (1%)
Query: 112 EELASKQKNEESKK----RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKA 167
EELA+ + + R+ ++DFEIGRPLGKGKFGNVYLAR K+S FI+ALKVLFK+
Sbjct: 18 EELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKS 77
Query: 168 QLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK 227
Q+EK G+EHQLRRE+EIQ+HL+HPNILRLY YFHDA RVYLILEYAP G +Y+ELQK K
Sbjct: 78 QIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEK 137
Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
DEQRTAT I ELA+AL+YCH K+VIHRDIKPENLLLG GE+KIADFGWSVH PS RR
Sbjct: 138 LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRK 197
Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT 347
T+CGTLDYLPPEMIEGR +DEKVDLW +GVLCYE LVG PPFE+ ++ ETY+RI +V+
Sbjct: 198 TMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVR 257
Query: 348 FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 389
FP + GARDLISRLL++ P +R L ++L+HPW+ A+S +
Sbjct: 258 FPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRR 299
>gi|62865641 aurora kinase C isoform 2 [Homo sapiens]
Length = 290
Score = 397 bits (1019), Expect = e-110
Identities = 189/272 (69%), Positives = 226/272 (83%)
Query: 118 QKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQ 177
Q+ R+ ++DFEIGRPLGKGKFGNVYLAR K+S FI+ALKVLFK+Q+EK G+EHQ
Sbjct: 9 QQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQ 68
Query: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
LRRE+EIQ+HL+HPNILRLY YFHDA RVYLILEYAP G +Y+ELQK K DEQRTAT I
Sbjct: 69 LRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATII 128
Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLP 297
ELA+AL+YCH K+VIHRDIKPENLLLG GE+KIADFGWSVH PS RR T+CGTLDYLP
Sbjct: 129 EELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLP 188
Query: 298 PEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGAR 357
PEMIEGR +DEKVDLW +GVLCYE LVG PPFE+ ++ ETY+RI +V+ FP + GAR
Sbjct: 189 PEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGAR 248
Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANSSK 389
DLISRLL++ P +R L ++L+HPW+ A+S +
Sbjct: 249 DLISRLLRYQPLERLPLAQILKHPWVQAHSRR 280
>gi|62865643 aurora kinase C isoform 3 [Homo sapiens]
Length = 275
Score = 396 bits (1018), Expect = e-110
Identities = 188/264 (71%), Positives = 224/264 (84%)
Query: 126 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQ 185
R+ ++DFEIGRPLGKGKFGNVYLAR K+S FI+ALKVLFK+Q+EK G+EHQLRRE+EIQ
Sbjct: 2 RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQ 61
Query: 186 SHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
+HL+HPNILRLY YFHDA RVYLILEYAP G +Y+ELQK K DEQRTAT I ELA+AL+
Sbjct: 62 AHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALT 121
Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRM 305
YCH K+VIHRDIKPENLLLG GE+KIADFGWSVH PS RR T+CGTLDYLPPEMIEGR
Sbjct: 122 YCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRT 181
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
+DEKVDLW +GVLCYE LVG PPFE+ ++ ETY+RI +V+ FP + GARDLISRLL+
Sbjct: 182 YDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLR 241
Query: 366 HNPSQRPMLREVLEHPWITANSSK 389
+ P +R L ++L+HPW+ A+S +
Sbjct: 242 YQPLERLPLAQILKHPWVQAHSRR 265
>gi|121114283 polo-like kinase 4 [Homo sapiens]
Length = 970
Score = 199 bits (505), Expect = 5e-51
Identities = 100/265 (37%), Positives = 158/265 (59%), Gaps = 3/265 (1%)
Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
+EDF++G LGKG F VY A + +A+K++ K + KAG+ +++ EV+I L+
Sbjct: 9 IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLK 68
Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQ-KLSKFDEQRTATYITELANALSYCH 248
HP+IL LY YF D+ VYL+LE G + R L+ ++ F E ++ ++ + Y H
Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSRRTTLCGTLDYLPPEMIEGRMH 306
S ++HRD+ NLLL +KIADFG + P + TLCGT +Y+ PE+ H
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAH 188
Query: 307 DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKH 366
+ D+WSLG + Y L+G+PPF+ +T + T ++ ++ P F++ A+DLI +LL+
Sbjct: 189 GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRR 248
Query: 367 NPSQRPMLREVLEHPWITANSSKPS 391
NP+ R L VL+HP+++ NSS S
Sbjct: 249 NPADRLSLSSVLDHPFMSRNSSTKS 273
>gi|156105707 SNF related kinase [Homo sapiens]
Length = 765
Score = 173 bits (438), Expect = 3e-43
Identities = 95/267 (35%), Positives = 152/267 (56%), Gaps = 5/267 (1%)
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
+++ + LG+G F V LAR + +A+KV+ K +L+ H L +EV ++HPN
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVRCMKLVQHPN 74
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I+RLY T++YLILE G ++ + K + +E Y ++ +A+SYCH
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134
Query: 252 VIHRDIKPENLLL-GSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
V+HRD+KPEN++ G +K+ DFG+S P + TT CG+L Y PE++ G +D
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAP 194
Query: 310 -VDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNP 368
VD+WSLGV+ + + G+PPF+ ET I ++T P V++ +DLI+R+L+ +P
Sbjct: 195 AVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDP 254
Query: 369 SQRPMLREVLEHPWITANSSKPSNCQN 395
+R L E+ HPW+ P+ N
Sbjct: 255 KRRASLEEIENHPWLQGVDPSPATKYN 281
>gi|156105705 SNF related kinase [Homo sapiens]
Length = 765
Score = 173 bits (438), Expect = 3e-43
Identities = 95/267 (35%), Positives = 152/267 (56%), Gaps = 5/267 (1%)
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
+++ + LG+G F V LAR + +A+KV+ K +L+ H L +EV ++HPN
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVRCMKLVQHPN 74
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
I+RLY T++YLILE G ++ + K + +E Y ++ +A+SYCH
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134
Query: 252 VIHRDIKPENLLL-GSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
V+HRD+KPEN++ G +K+ DFG+S P + TT CG+L Y PE++ G +D
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAP 194
Query: 310 -VDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNP 368
VD+WSLGV+ + + G+PPF+ ET I ++T P V++ +DLI+R+L+ +P
Sbjct: 195 AVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDP 254
Query: 369 SQRPMLREVLEHPWITANSSKPSNCQN 395
+R L E+ HPW+ P+ N
Sbjct: 255 KRRASLEEIENHPWLQGVDPSPATKYN 281
>gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform 1
[Homo sapiens]
Length = 556
Score = 171 bits (433), Expect = 1e-42
Identities = 103/334 (30%), Positives = 163/334 (48%), Gaps = 29/334 (8%)
Query: 43 QAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSV-PHPVSRPLNNTQKSKQP 101
Q+ VLC S + Q + P +++ + T+ P P + L + Q QP
Sbjct: 15 QSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQP 74
Query: 102 LPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILAL 161
PE DF+ G+ LG+G F V LARE + A+
Sbjct: 75 RKKRPE------------------------DFKFGKILGEGSFSTVVLARELATSREYAI 110
Query: 162 KVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRE 221
K+L K + K + RE ++ S L HP ++LY F D ++Y L YA G + +
Sbjct: 111 KILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKY 170
Query: 222 LQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----W 277
++K+ FDE T Y E+ +AL Y H K +IHRD+KPEN+LL ++I DFG
Sbjct: 171 IRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL 230
Query: 278 SVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQET 337
S + +R + GT Y+ PE++ + + DLW+LG + Y+ + G PPF A
Sbjct: 231 SPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLI 290
Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
+++I ++E+ FP+ ARDL+ +LL + ++R
Sbjct: 291 FQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 324
>gi|193083129 MAP/microtubule affinity-regulating kinase 3 isoform d
[Homo sapiens]
Length = 713
Score = 171 bits (433), Expect = 1e-42
Identities = 98/308 (31%), Positives = 166/308 (53%), Gaps = 21/308 (6%)
Query: 98 SKQPLPSAPENNPE---------EELASKQKNEESKKR---------QWALEDFEIGRPL 139
++ PLP+ E + E +E+ S+ ++ R Q + ++ + + +
Sbjct: 3 TRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTI 62
Query: 140 GKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGY 199
GKG F V LAR + +A+K++ K QL ++ +L REV I L HPNI++L+
Sbjct: 63 GKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHPNIVKLFEV 121
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
+YLI+EYA G V+ L + E+ + ++ +A+ YCH KR++HRD+K
Sbjct: 122 IETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKA 181
Query: 260 ENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGV 317
ENLLL + +KIADFG+S + T CG+ Y PE+ +G+ +D +VD+WSLGV
Sbjct: 182 ENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGV 241
Query: 318 LCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ Y + G PF+ +E +R+ R ++ P +++ +L+ R L NP +R L ++
Sbjct: 242 ILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQI 301
Query: 378 LEHPWITA 385
++ WI A
Sbjct: 302 MKDRWINA 309
>gi|193083127 MAP/microtubule affinity-regulating kinase 3 isoform b
[Homo sapiens]
Length = 744
Score = 171 bits (433), Expect = 1e-42
Identities = 98/308 (31%), Positives = 166/308 (53%), Gaps = 21/308 (6%)
Query: 98 SKQPLPSAPENNPE---------EELASKQKNEESKKR---------QWALEDFEIGRPL 139
++ PLP+ E + E +E+ S+ ++ R Q + ++ + + +
Sbjct: 3 TRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTI 62
Query: 140 GKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGY 199
GKG F V LAR + +A+K++ K QL ++ +L REV I L HPNI++L+
Sbjct: 63 GKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHPNIVKLFEV 121
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
+YLI+EYA G V+ L + E+ + ++ +A+ YCH KR++HRD+K
Sbjct: 122 IETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKA 181
Query: 260 ENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGV 317
ENLLL + +KIADFG+S + T CG+ Y PE+ +G+ +D +VD+WSLGV
Sbjct: 182 ENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGV 241
Query: 318 LCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ Y + G PF+ +E +R+ R ++ P +++ +L+ R L NP +R L ++
Sbjct: 242 ILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQI 301
Query: 378 LEHPWITA 385
++ WI A
Sbjct: 302 MKDRWINA 309
>gi|193083125 MAP/microtubule affinity-regulating kinase 3 isoform a
[Homo sapiens]
Length = 753
Score = 171 bits (433), Expect = 1e-42
Identities = 98/308 (31%), Positives = 166/308 (53%), Gaps = 21/308 (6%)
Query: 98 SKQPLPSAPENNPE---------EELASKQKNEESKKR---------QWALEDFEIGRPL 139
++ PLP+ E + E +E+ S+ ++ R Q + ++ + + +
Sbjct: 3 TRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTI 62
Query: 140 GKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGY 199
GKG F V LAR + +A+K++ K QL ++ +L REV I L HPNI++L+
Sbjct: 63 GKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHPNIVKLFEV 121
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
+YLI+EYA G V+ L + E+ + ++ +A+ YCH KR++HRD+K
Sbjct: 122 IETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKA 181
Query: 260 ENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGV 317
ENLLL + +KIADFG+S + T CG+ Y PE+ +G+ +D +VD+WSLGV
Sbjct: 182 ENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGV 241
Query: 318 LCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ Y + G PF+ +E +R+ R ++ P +++ +L+ R L NP +R L ++
Sbjct: 242 ILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQI 301
Query: 378 LEHPWITA 385
++ WI A
Sbjct: 302 MKDRWINA 309
>gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform c
[Homo sapiens]
Length = 729
Score = 171 bits (433), Expect = 1e-42
Identities = 98/308 (31%), Positives = 166/308 (53%), Gaps = 21/308 (6%)
Query: 98 SKQPLPSAPENNPE---------EELASKQKNEESKKR---------QWALEDFEIGRPL 139
++ PLP+ E + E +E+ S+ ++ R Q + ++ + + +
Sbjct: 3 TRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTI 62
Query: 140 GKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGY 199
GKG F V LAR + +A+K++ K QL ++ +L REV I L HPNI++L+
Sbjct: 63 GKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHPNIVKLFEV 121
Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
+YLI+EYA G V+ L + E+ + ++ +A+ YCH KR++HRD+K
Sbjct: 122 IETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKA 181
Query: 260 ENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGV 317
ENLLL + +KIADFG+S + T CG+ Y PE+ +G+ +D +VD+WSLGV
Sbjct: 182 ENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGV 241
Query: 318 LCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
+ Y + G PF+ +E +R+ R ++ P +++ +L+ R L NP +R L ++
Sbjct: 242 ILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQI 301
Query: 378 LEHPWITA 385
++ WI A
Sbjct: 302 MKDRWINA 309
>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
sapiens]
Length = 688
Score = 171 bits (433), Expect = 1e-42
Identities = 87/254 (34%), Positives = 147/254 (57%), Gaps = 3/254 (1%)
Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
++ + R +GKG F V LAR + +A+K++ K QL + ++ +L REV I L HP
Sbjct: 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQ-KLFREVRIMKGLNHP 116
Query: 192 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKR 251
NI++L+ +YL++EYA G V+ L + E+ ++ +A+ YCH K
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176
Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EK 309
++HRD+K ENLLL + +KIADFG+S S+ T CG+ Y PE+ +G+ +D +
Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 236
Query: 310 VDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPS 369
VD+WSLGV+ Y + G PF+ + +E +R+ R ++ P +++ ++ R L NP+
Sbjct: 237 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPA 296
Query: 370 QRPMLREVLEHPWI 383
+R L ++++ WI
Sbjct: 297 KRCTLEQIMKDKWI 310
>gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent
protein kinase-1 [Homo sapiens]
Length = 471
Score = 170 bits (431), Expect = 2e-42
Identities = 103/334 (30%), Positives = 162/334 (48%), Gaps = 29/334 (8%)
Query: 43 QAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSV-PHPVSRPLNNTQKSKQP 101
Q+ VLC S + Q + P +++ + T+ P P + L + Q QP
Sbjct: 34 QSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQP 93
Query: 102 LPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILAL 161
PE DF+ G+ LG+G F V LARE + A+
Sbjct: 94 RKKRPE------------------------DFKFGKILGEGSFSTVVLARELATSREYAI 129
Query: 162 KVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRE 221
K+L K + K + RE ++ S L HP ++LY F R+Y L YA G + +
Sbjct: 130 KILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQTTRRLYFGLSYAKNGELLKY 189
Query: 222 LQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----W 277
++K+ FDE T Y E+ +AL Y H K +IHRD+KPEN+LL ++I DFG
Sbjct: 190 IRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL 249
Query: 278 SVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQET 337
S + +R + GT Y+ PE++ + + DLW+LG + Y+ + G PPF A
Sbjct: 250 SPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLI 309
Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
+++I ++E+ FP+ ARDL+ +LL + ++R
Sbjct: 310 FQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 343
>gi|150456432 unc-51-like kinase 3 [Homo sapiens]
Length = 472
Score = 169 bits (429), Expect = 3e-42
Identities = 92/261 (35%), Positives = 155/261 (59%), Gaps = 8/261 (3%)
Query: 130 LEDFEIGRPLGKGKFGNVYLA-REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
L+ F + LG G + VY A +K ++ ++A+K + K L KA VE+ L E+EI +
Sbjct: 11 LDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLT-EIEILKGI 69
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
RHP+I++L + D+ +YLI+E+ G + R + E+ ++ +LA+AL + H
Sbjct: 70 RHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLH 129
Query: 249 SKRVIHRDIKPENLLLGSAGE--LKIADFGWSVH-APSSRRTTLCGTLDYLPPEMIEGRM 305
+ + H D+KP+N+LL S + LK+ADFG++ H +P + L G+ Y+ PEM+ R
Sbjct: 130 ERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQ 189
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR---VEFTFPDFVTEGARDLISR 362
+D +VDLWS+GV+ YE L G+PPF + ++ E ++I +E ++ RDL+ R
Sbjct: 190 YDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLLQR 249
Query: 363 LLKHNPSQRPMLREVLEHPWI 383
LL+ +PS+R ++ HPW+
Sbjct: 250 LLERDPSRRISFQDFFAHPWV 270
>gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]
Length = 1263
Score = 169 bits (427), Expect = 5e-42
Identities = 89/261 (34%), Positives = 147/261 (56%), Gaps = 3/261 (1%)
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
+EI R +GKG F V A +K +A+K++ K QL++ ++ ++ REV+I L HP+
Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLK-KIFREVQIMKMLCHPH 66
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
I+RLY +YL+ EYA G ++ L + E+ ++ A+ +CH + +
Sbjct: 67 IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 126
Query: 253 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 310
+HRD+K ENLLL + +KIADFG+S + P T CG+ Y PE+ EG+ +D KV
Sbjct: 127 VHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKV 186
Query: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
D+WSLGV+ Y + G PF+ +T Q R+ +F P F++ LI +L +P++
Sbjct: 187 DIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNK 246
Query: 371 RPMLREVLEHPWITANSSKPS 391
R + ++ +H W+ + P+
Sbjct: 247 RLSMEQICKHKWMKLGDADPN 267
>gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [Homo
sapiens]
Length = 482
Score = 169 bits (427), Expect = 5e-42
Identities = 95/246 (38%), Positives = 141/246 (57%), Gaps = 8/246 (3%)
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKF---ILALKVLFKAQLEKAGVEH-QLRREVEIQSHL 188
FE+ R LGKG +G V+ R+ Q I A+KVL KA++ + + R E I +
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
+HP I+ L F ++YLILE G ++ L++ F E Y+ E+ AL + H
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186
Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGW---SVHAPSSRRTTLCGTLDYLPPEMIEGRM 305
S+ +I+RD+KPEN++L S G +K+ DFG S+H + T CGT++Y+ PE++
Sbjct: 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHT-FCGTIEYMAPEILVRSG 245
Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
H+ VD WSLG L Y+ L G PPF A ++T +I R + P ++T ARDL+ + LK
Sbjct: 246 HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLK 305
Query: 366 HNPSQR 371
NPSQR
Sbjct: 306 RNPSQR 311
>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
[Homo sapiens]
Length = 709
Score = 168 bits (425), Expect = 9e-42
Identities = 92/297 (30%), Positives = 164/297 (55%), Gaps = 5/297 (1%)
Query: 91 PLNNTQKSKQPLPSAPENNPEEE--LASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVY 148
P N + ++QP ++ P + + + + S Q + ++ + + +GKG F V
Sbjct: 9 PTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVK 68
Query: 149 LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYL 208
LAR + +A+K++ K QL + ++ +L REV I L HPNI++L+ +YL
Sbjct: 69 LARHILTGKEVAVKIIDKTQLNSSSLQ-KLFREVRIMKVLNHPNIVKLFEVIETEKTLYL 127
Query: 209 ILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG 268
++EYA G V+ L + E+ ++ +A+ YCH K ++HRD+K ENLLL +
Sbjct: 128 VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADM 187
Query: 269 ELKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGVLCYEFLVGK 326
+KIADFG+S ++ T CG+ Y PE+ +G+ +D +VD+WSLGV+ Y + G
Sbjct: 188 NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 247
Query: 327 PPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
PF+ +E +R+ R ++ P +++ +L+ + L NPS+R L ++++ W+
Sbjct: 248 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
[Homo sapiens]
Length = 719
Score = 168 bits (425), Expect = 9e-42
Identities = 92/297 (30%), Positives = 164/297 (55%), Gaps = 5/297 (1%)
Query: 91 PLNNTQKSKQPLPSAPENNPEEE--LASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVY 148
P N + ++QP ++ P + + + + S Q + ++ + + +GKG F V
Sbjct: 9 PTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVK 68
Query: 149 LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYL 208
LAR + +A+K++ K QL + ++ +L REV I L HPNI++L+ +YL
Sbjct: 69 LARHILTGKEVAVKIIDKTQLNSSSLQ-KLFREVRIMKVLNHPNIVKLFEVIETEKTLYL 127
Query: 209 ILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG 268
++EYA G V+ L + E+ ++ +A+ YCH K ++HRD+K ENLLL +
Sbjct: 128 VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADM 187
Query: 269 ELKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGVLCYEFLVGK 326
+KIADFG+S ++ T CG+ Y PE+ +G+ +D +VD+WSLGV+ Y + G
Sbjct: 188 NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 247
Query: 327 PPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
PF+ +E +R+ R ++ P +++ +L+ + L NPS+R L ++++ W+
Sbjct: 248 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>gi|254028234 MAP/microtubule affinity-regulating kinase 2 isoform d
[Homo sapiens]
Length = 788
Score = 168 bits (425), Expect = 9e-42
Identities = 92/297 (30%), Positives = 164/297 (55%), Gaps = 5/297 (1%)
Query: 91 PLNNTQKSKQPLPSAPENNPEEE--LASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVY 148
P N + ++QP ++ P + + + + S Q + ++ + + +GKG F V
Sbjct: 9 PTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVK 68
Query: 149 LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYL 208
LAR + +A+K++ K QL + ++ +L REV I L HPNI++L+ +YL
Sbjct: 69 LARHILTGKEVAVKIIDKTQLNSSSLQ-KLFREVRIMKVLNHPNIVKLFEVIETEKTLYL 127
Query: 209 ILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG 268
++EYA G V+ L + E+ ++ +A+ YCH K ++HRD+K ENLLL +
Sbjct: 128 VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADM 187
Query: 269 ELKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGVLCYEFLVGK 326
+KIADFG+S ++ T CG+ Y PE+ +G+ +D +VD+WSLGV+ Y + G
Sbjct: 188 NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 247
Query: 327 PPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
PF+ +E +R+ R ++ P +++ +L+ + L NPS+R L ++++ W+
Sbjct: 248 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
[Homo sapiens]
Length = 724
Score = 168 bits (425), Expect = 9e-42
Identities = 92/297 (30%), Positives = 164/297 (55%), Gaps = 5/297 (1%)
Query: 91 PLNNTQKSKQPLPSAPENNPEEE--LASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVY 148
P N + ++QP ++ P + + + + S Q + ++ + + +GKG F V
Sbjct: 9 PTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVK 68
Query: 149 LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYL 208
LAR + +A+K++ K QL + ++ +L REV I L HPNI++L+ +YL
Sbjct: 69 LARHILTGKEVAVKIIDKTQLNSSSLQ-KLFREVRIMKVLNHPNIVKLFEVIETEKTLYL 127
Query: 209 ILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG 268
++EYA G V+ L + E+ ++ +A+ YCH K ++HRD+K ENLLL +
Sbjct: 128 VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADM 187
Query: 269 ELKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGVLCYEFLVGK 326
+KIADFG+S ++ T CG+ Y PE+ +G+ +D +VD+WSLGV+ Y + G
Sbjct: 188 NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 247
Query: 327 PPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
PF+ +E +R+ R ++ P +++ +L+ + L NPS+R L ++++ W+
Sbjct: 248 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo
sapiens]
Length = 396
Score = 167 bits (424), Expect = 1e-41
Identities = 88/245 (35%), Positives = 138/245 (56%), Gaps = 4/245 (1%)
Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
EDF+ G+ LG+G F V LARE + A+K+L K + K + RE ++ S L H
Sbjct: 53 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 112
Query: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
P ++LY F D ++Y L YA G + + ++K+ FDE T Y E+ +AL Y H K
Sbjct: 113 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 172
Query: 251 RVIHRDIKPENLLLGSAGELKIADFG----WSVHAPSSRRTTLCGTLDYLPPEMIEGRMH 306
+IHRD+KPEN+LL ++I DFG S + +R + GT Y+ PE++ +
Sbjct: 173 GIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSA 232
Query: 307 DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKH 366
+ DLW+LG + Y+ + G PPF A +++I ++E+ FP+ ARDL+ +LL
Sbjct: 233 CKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVL 292
Query: 367 NPSQR 371
+ ++R
Sbjct: 293 DATKR 297
>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
Length = 926
Score = 166 bits (421), Expect = 3e-41
Identities = 87/253 (34%), Positives = 146/253 (57%), Gaps = 3/253 (1%)
Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
++I LGKG F V L R + +K +A+K++ K+QL+ +E ++ REV+I L HP+
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLE-KIYREVQIMKMLDHPH 78
Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
I++LY + +YL+ EYA G ++ L + +E ++ +A+ YCH +++
Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138
Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEMIEGRMHD-EKV 310
+HRD+K ENLLL + +KIADFG+ S T CG+ Y PE+ EG+ ++ ++
Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQL 198
Query: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
D+WS+GV+ Y + G PF+ T +R+ F P F++E LI R+L +PS+
Sbjct: 199 DIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK 258
Query: 371 RPMLREVLEHPWI 383
R + ++ EH W+
Sbjct: 259 RLTIAQIKEHKWM 271
>gi|4826948 protein kinase, X-linked [Homo sapiens]
Length = 358
Score = 166 bits (420), Expect = 3e-41
Identities = 85/244 (34%), Positives = 139/244 (56%), Gaps = 1/244 (0%)
Query: 128 WALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSH 187
++L+DF+ +G G FG V+L +EK +K ALKV+ + + E + E +
Sbjct: 44 YSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKE 103
Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYC 247
+ HP ++RL+ +HD +Y+++EY P G ++ L+ +F Y E+ A+ Y
Sbjct: 104 VSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYL 163
Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHD 307
HSK +++RD+KPEN+LL G +K+ DFG++ R TLCGT +YL PE+I+ + H
Sbjct: 164 HSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKL-VDRTWTLCGTPEYLAPEVIQSKGHG 222
Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
VD W+LG+L +E L G PPF + Y++I + FP + +DLI +LL +
Sbjct: 223 RAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVD 282
Query: 368 PSQR 371
++R
Sbjct: 283 RTRR 286
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,429,709
Number of Sequences: 37866
Number of extensions: 791337
Number of successful extensions: 6286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 765
Number of HSP's successfully gapped in prelim test: 156
Number of HSP's that attempted gapping in prelim test: 3424
Number of HSP's gapped (non-prelim): 1231
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.