Guide to the Human Genome
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Search of human proteins with 38327562

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38327562 serine/threonine protein kinase 6 [Homo sapiens]
         (403 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]          817   0.0  
gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]          817   0.0  
gi|38327568 serine/threonine protein kinase 6 [Homo sapiens]          817   0.0  
gi|38327566 serine/threonine protein kinase 6 [Homo sapiens]          817   0.0  
gi|38327564 serine/threonine protein kinase 6 [Homo sapiens]          817   0.0  
gi|38327562 serine/threonine protein kinase 6 [Homo sapiens]          817   0.0  
gi|83776600 aurora kinase B [Homo sapiens]                            406   e-113
gi|62865639 aurora kinase C isoform 1 [Homo sapiens]                  398   e-111
gi|62865641 aurora kinase C isoform 2 [Homo sapiens]                  397   e-110
gi|62865643 aurora kinase C isoform 3 [Homo sapiens]                  396   e-110
gi|121114283 polo-like kinase 4 [Homo sapiens]                        199   5e-51
gi|156105707 SNF related kinase [Homo sapiens]                        173   3e-43
gi|156105705 SNF related kinase [Homo sapiens]                        173   3e-43
gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform...   171   1e-42
gi|193083129 MAP/microtubule affinity-regulating kinase 3 isofor...   171   1e-42
gi|193083127 MAP/microtubule affinity-regulating kinase 3 isofor...   171   1e-42
gi|193083125 MAP/microtubule affinity-regulating kinase 3 isofor...   171   1e-42
gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform...   171   1e-42
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s...   171   1e-42
gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent ...   170   2e-42
gi|150456432 unc-51-like kinase 3 [Homo sapiens]                      169   3e-42
gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]        169   5e-42
gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [H...   169   5e-42
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor...   168   9e-42
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor...   168   9e-42
gi|254028234 MAP/microtubule affinity-regulating kinase 2 isofor...   168   9e-42
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor...   168   9e-42
gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo ...   167   1e-41
gi|38569460 SNF1-like kinase 2 [Homo sapiens]                         166   3e-41
gi|4826948 protein kinase, X-linked [Homo sapiens]                    166   3e-41

>gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score =  817 bits (2110), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
           MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60

Query: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
           AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120

Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
           EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180

Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
           EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240

Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
           ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300

Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
           IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360

Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
           SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403


>gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score =  817 bits (2110), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
           MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60

Query: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
           AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120

Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
           EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180

Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
           EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240

Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
           ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300

Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
           IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360

Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
           SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403


>gi|38327568 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score =  817 bits (2110), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
           MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60

Query: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
           AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120

Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
           EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180

Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
           EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240

Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
           ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300

Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
           IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360

Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
           SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403


>gi|38327566 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score =  817 bits (2110), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
           MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60

Query: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
           AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120

Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
           EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180

Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
           EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240

Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
           ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300

Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
           IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360

Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
           SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403


>gi|38327564 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score =  817 bits (2110), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
           MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60

Query: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
           AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120

Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
           EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180

Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
           EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240

Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
           ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300

Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
           IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360

Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
           SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403


>gi|38327562 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score =  817 bits (2110), Expect = 0.0
 Identities = 403/403 (100%), Positives = 403/403 (100%)

Query: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60
           MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ
Sbjct: 1   MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQ 60

Query: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120
           AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN
Sbjct: 61  AQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKN 120

Query: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180
           EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR
Sbjct: 121 EESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRR 180

Query: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
           EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240

Query: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300
           ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM
Sbjct: 241 ANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 300

Query: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360
           IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI
Sbjct: 301 IEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLI 360

Query: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
           SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Sbjct: 361 SRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403


>gi|83776600 aurora kinase B [Homo sapiens]
          Length = 344

 Score =  406 bits (1044), Expect = e-113
 Identities = 192/264 (72%), Positives = 224/264 (84%)

Query: 126 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQ 185
           R + ++DFEIGRPLGKGKFGNVYLAREK+S FI+ALKVLFK+Q+EK GVEHQLRRE+EIQ
Sbjct: 70  RHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQ 129

Query: 186 SHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
           +HL HPNILRLY YF+D  R+YLILEYAP G +Y+ELQK   FDEQRTAT + ELA+AL 
Sbjct: 130 AHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALM 189

Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRM 305
           YCH K+VIHRDIKPENLLLG  GELKIADFGWSVHAPS RR T+CGTLDYLPPEMIEGRM
Sbjct: 190 YCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRM 249

Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
           H+EKVDLW +GVLCYE LVG PPFE+ ++ ETY+RI +V+  FP  V  GA+DLIS+LL+
Sbjct: 250 HNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLR 309

Query: 366 HNPSQRPMLREVLEHPWITANSSK 389
           HNPS+R  L +V  HPW+ ANS +
Sbjct: 310 HNPSERLPLAQVSAHPWVRANSRR 333


>gi|62865639 aurora kinase C isoform 1 [Homo sapiens]
          Length = 309

 Score =  398 bits (1022), Expect = e-111
 Identities = 192/282 (68%), Positives = 231/282 (81%), Gaps = 4/282 (1%)

Query: 112 EELASKQKNEESKK----RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKA 167
           EELA+  +  +       R+  ++DFEIGRPLGKGKFGNVYLAR K+S FI+ALKVLFK+
Sbjct: 18  EELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKS 77

Query: 168 QLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK 227
           Q+EK G+EHQLRRE+EIQ+HL+HPNILRLY YFHDA RVYLILEYAP G +Y+ELQK  K
Sbjct: 78  QIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEK 137

Query: 228 FDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT 287
            DEQRTAT I ELA+AL+YCH K+VIHRDIKPENLLLG  GE+KIADFGWSVH PS RR 
Sbjct: 138 LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRK 197

Query: 288 TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFT 347
           T+CGTLDYLPPEMIEGR +DEKVDLW +GVLCYE LVG PPFE+ ++ ETY+RI +V+  
Sbjct: 198 TMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVR 257

Query: 348 FPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 389
           FP  +  GARDLISRLL++ P +R  L ++L+HPW+ A+S +
Sbjct: 258 FPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRR 299


>gi|62865641 aurora kinase C isoform 2 [Homo sapiens]
          Length = 290

 Score =  397 bits (1019), Expect = e-110
 Identities = 189/272 (69%), Positives = 226/272 (83%)

Query: 118 QKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQ 177
           Q+      R+  ++DFEIGRPLGKGKFGNVYLAR K+S FI+ALKVLFK+Q+EK G+EHQ
Sbjct: 9   QQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQ 68

Query: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
           LRRE+EIQ+HL+HPNILRLY YFHDA RVYLILEYAP G +Y+ELQK  K DEQRTAT I
Sbjct: 69  LRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATII 128

Query: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLP 297
            ELA+AL+YCH K+VIHRDIKPENLLLG  GE+KIADFGWSVH PS RR T+CGTLDYLP
Sbjct: 129 EELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLP 188

Query: 298 PEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGAR 357
           PEMIEGR +DEKVDLW +GVLCYE LVG PPFE+ ++ ETY+RI +V+  FP  +  GAR
Sbjct: 189 PEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGAR 248

Query: 358 DLISRLLKHNPSQRPMLREVLEHPWITANSSK 389
           DLISRLL++ P +R  L ++L+HPW+ A+S +
Sbjct: 249 DLISRLLRYQPLERLPLAQILKHPWVQAHSRR 280


>gi|62865643 aurora kinase C isoform 3 [Homo sapiens]
          Length = 275

 Score =  396 bits (1018), Expect = e-110
 Identities = 188/264 (71%), Positives = 224/264 (84%)

Query: 126 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQ 185
           R+  ++DFEIGRPLGKGKFGNVYLAR K+S FI+ALKVLFK+Q+EK G+EHQLRRE+EIQ
Sbjct: 2   RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQ 61

Query: 186 SHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 245
           +HL+HPNILRLY YFHDA RVYLILEYAP G +Y+ELQK  K DEQRTAT I ELA+AL+
Sbjct: 62  AHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALT 121

Query: 246 YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRM 305
           YCH K+VIHRDIKPENLLLG  GE+KIADFGWSVH PS RR T+CGTLDYLPPEMIEGR 
Sbjct: 122 YCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRT 181

Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
           +DEKVDLW +GVLCYE LVG PPFE+ ++ ETY+RI +V+  FP  +  GARDLISRLL+
Sbjct: 182 YDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLR 241

Query: 366 HNPSQRPMLREVLEHPWITANSSK 389
           + P +R  L ++L+HPW+ A+S +
Sbjct: 242 YQPLERLPLAQILKHPWVQAHSRR 265


>gi|121114283 polo-like kinase 4 [Homo sapiens]
          Length = 970

 Score =  199 bits (505), Expect = 5e-51
 Identities = 100/265 (37%), Positives = 158/265 (59%), Gaps = 3/265 (1%)

Query: 130 LEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR 189
           +EDF++G  LGKG F  VY A    +   +A+K++ K  + KAG+  +++ EV+I   L+
Sbjct: 9   IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLK 68

Query: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQ-KLSKFDEQRTATYITELANALSYCH 248
           HP+IL LY YF D+  VYL+LE    G + R L+ ++  F E     ++ ++   + Y H
Sbjct: 69  HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128

Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWSVHA--PSSRRTTLCGTLDYLPPEMIEGRMH 306
           S  ++HRD+   NLLL     +KIADFG +     P  +  TLCGT +Y+ PE+     H
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAH 188

Query: 307 DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKH 366
             + D+WSLG + Y  L+G+PPF+ +T + T  ++   ++  P F++  A+DLI +LL+ 
Sbjct: 189 GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRR 248

Query: 367 NPSQRPMLREVLEHPWITANSSKPS 391
           NP+ R  L  VL+HP+++ NSS  S
Sbjct: 249 NPADRLSLSSVLDHPFMSRNSSTKS 273


>gi|156105707 SNF related kinase [Homo sapiens]
          Length = 765

 Score =  173 bits (438), Expect = 3e-43
 Identities = 95/267 (35%), Positives = 152/267 (56%), Gaps = 5/267 (1%)

Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
           +++ + LG+G F  V LAR   +   +A+KV+ K +L+     H L +EV     ++HPN
Sbjct: 16  YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVRCMKLVQHPN 74

Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
           I+RLY      T++YLILE    G ++  + K  +  +E     Y  ++ +A+SYCH   
Sbjct: 75  IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134

Query: 252 VIHRDIKPENLLL-GSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
           V+HRD+KPEN++     G +K+ DFG+S    P  + TT CG+L Y  PE++ G  +D  
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAP 194

Query: 310 -VDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNP 368
            VD+WSLGV+ +  + G+PPF+     ET   I   ++T P  V++  +DLI+R+L+ +P
Sbjct: 195 AVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDP 254

Query: 369 SQRPMLREVLEHPWITANSSKPSNCQN 395
            +R  L E+  HPW+      P+   N
Sbjct: 255 KRRASLEEIENHPWLQGVDPSPATKYN 281


>gi|156105705 SNF related kinase [Homo sapiens]
          Length = 765

 Score =  173 bits (438), Expect = 3e-43
 Identities = 95/267 (35%), Positives = 152/267 (56%), Gaps = 5/267 (1%)

Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
           +++ + LG+G F  V LAR   +   +A+KV+ K +L+     H L +EV     ++HPN
Sbjct: 16  YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVRCMKLVQHPN 74

Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSK-FDEQRTATYITELANALSYCHSKR 251
           I+RLY      T++YLILE    G ++  + K  +  +E     Y  ++ +A+SYCH   
Sbjct: 75  IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134

Query: 252 VIHRDIKPENLLL-GSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 309
           V+HRD+KPEN++     G +K+ DFG+S    P  + TT CG+L Y  PE++ G  +D  
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAP 194

Query: 310 -VDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNP 368
            VD+WSLGV+ +  + G+PPF+     ET   I   ++T P  V++  +DLI+R+L+ +P
Sbjct: 195 AVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDP 254

Query: 369 SQRPMLREVLEHPWITANSSKPSNCQN 395
            +R  L E+  HPW+      P+   N
Sbjct: 255 KRRASLEEIENHPWLQGVDPSPATKYN 281


>gi|4505695 3-phosphoinositide dependent protein kinase-1 isoform 1
           [Homo sapiens]
          Length = 556

 Score =  171 bits (433), Expect = 1e-42
 Identities = 103/334 (30%), Positives = 163/334 (48%), Gaps = 29/334 (8%)

Query: 43  QAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSV-PHPVSRPLNNTQKSKQP 101
           Q+  VLC   S   +  Q +       P  +++   +  T+  P P +  L + Q   QP
Sbjct: 15  QSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQP 74

Query: 102 LPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILAL 161
               PE                        DF+ G+ LG+G F  V LARE  +    A+
Sbjct: 75  RKKRPE------------------------DFKFGKILGEGSFSTVVLARELATSREYAI 110

Query: 162 KVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRE 221
           K+L K  + K      + RE ++ S L HP  ++LY  F D  ++Y  L YA  G + + 
Sbjct: 111 KILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKY 170

Query: 222 LQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----W 277
           ++K+  FDE  T  Y  E+ +AL Y H K +IHRD+KPEN+LL     ++I DFG     
Sbjct: 171 IRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL 230

Query: 278 SVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQET 337
           S  +  +R  +  GT  Y+ PE++  +   +  DLW+LG + Y+ + G PPF A      
Sbjct: 231 SPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLI 290

Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
           +++I ++E+ FP+     ARDL+ +LL  + ++R
Sbjct: 291 FQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 324


>gi|193083129 MAP/microtubule affinity-regulating kinase 3 isoform d
           [Homo sapiens]
          Length = 713

 Score =  171 bits (433), Expect = 1e-42
 Identities = 98/308 (31%), Positives = 166/308 (53%), Gaps = 21/308 (6%)

Query: 98  SKQPLPSAPENNPE---------EELASKQKNEESKKR---------QWALEDFEIGRPL 139
           ++ PLP+  E + E         +E+ S+     ++ R         Q  + ++ + + +
Sbjct: 3   TRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTI 62

Query: 140 GKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGY 199
           GKG F  V LAR   +   +A+K++ K QL    ++ +L REV I   L HPNI++L+  
Sbjct: 63  GKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHPNIVKLFEV 121

Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
                 +YLI+EYA  G V+  L    +  E+   +   ++ +A+ YCH KR++HRD+K 
Sbjct: 122 IETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKA 181

Query: 260 ENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGV 317
           ENLLL +   +KIADFG+S       +  T CG+  Y  PE+ +G+ +D  +VD+WSLGV
Sbjct: 182 ENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGV 241

Query: 318 LCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
           + Y  + G  PF+    +E  +R+ R ++  P +++    +L+ R L  NP +R  L ++
Sbjct: 242 ILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQI 301

Query: 378 LEHPWITA 385
           ++  WI A
Sbjct: 302 MKDRWINA 309


>gi|193083127 MAP/microtubule affinity-regulating kinase 3 isoform b
           [Homo sapiens]
          Length = 744

 Score =  171 bits (433), Expect = 1e-42
 Identities = 98/308 (31%), Positives = 166/308 (53%), Gaps = 21/308 (6%)

Query: 98  SKQPLPSAPENNPE---------EELASKQKNEESKKR---------QWALEDFEIGRPL 139
           ++ PLP+  E + E         +E+ S+     ++ R         Q  + ++ + + +
Sbjct: 3   TRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTI 62

Query: 140 GKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGY 199
           GKG F  V LAR   +   +A+K++ K QL    ++ +L REV I   L HPNI++L+  
Sbjct: 63  GKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHPNIVKLFEV 121

Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
                 +YLI+EYA  G V+  L    +  E+   +   ++ +A+ YCH KR++HRD+K 
Sbjct: 122 IETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKA 181

Query: 260 ENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGV 317
           ENLLL +   +KIADFG+S       +  T CG+  Y  PE+ +G+ +D  +VD+WSLGV
Sbjct: 182 ENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGV 241

Query: 318 LCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
           + Y  + G  PF+    +E  +R+ R ++  P +++    +L+ R L  NP +R  L ++
Sbjct: 242 ILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQI 301

Query: 378 LEHPWITA 385
           ++  WI A
Sbjct: 302 MKDRWINA 309


>gi|193083125 MAP/microtubule affinity-regulating kinase 3 isoform a
           [Homo sapiens]
          Length = 753

 Score =  171 bits (433), Expect = 1e-42
 Identities = 98/308 (31%), Positives = 166/308 (53%), Gaps = 21/308 (6%)

Query: 98  SKQPLPSAPENNPE---------EELASKQKNEESKKR---------QWALEDFEIGRPL 139
           ++ PLP+  E + E         +E+ S+     ++ R         Q  + ++ + + +
Sbjct: 3   TRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTI 62

Query: 140 GKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGY 199
           GKG F  V LAR   +   +A+K++ K QL    ++ +L REV I   L HPNI++L+  
Sbjct: 63  GKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHPNIVKLFEV 121

Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
                 +YLI+EYA  G V+  L    +  E+   +   ++ +A+ YCH KR++HRD+K 
Sbjct: 122 IETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKA 181

Query: 260 ENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGV 317
           ENLLL +   +KIADFG+S       +  T CG+  Y  PE+ +G+ +D  +VD+WSLGV
Sbjct: 182 ENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGV 241

Query: 318 LCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
           + Y  + G  PF+    +E  +R+ R ++  P +++    +L+ R L  NP +R  L ++
Sbjct: 242 ILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQI 301

Query: 378 LEHPWITA 385
           ++  WI A
Sbjct: 302 MKDRWINA 309


>gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform c
           [Homo sapiens]
          Length = 729

 Score =  171 bits (433), Expect = 1e-42
 Identities = 98/308 (31%), Positives = 166/308 (53%), Gaps = 21/308 (6%)

Query: 98  SKQPLPSAPENNPE---------EELASKQKNEESKKR---------QWALEDFEIGRPL 139
           ++ PLP+  E + E         +E+ S+     ++ R         Q  + ++ + + +
Sbjct: 3   TRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTI 62

Query: 140 GKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGY 199
           GKG F  V LAR   +   +A+K++ K QL    ++ +L REV I   L HPNI++L+  
Sbjct: 63  GKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHPNIVKLFEV 121

Query: 200 FHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKP 259
                 +YLI+EYA  G V+  L    +  E+   +   ++ +A+ YCH KR++HRD+K 
Sbjct: 122 IETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKA 181

Query: 260 ENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGV 317
           ENLLL +   +KIADFG+S       +  T CG+  Y  PE+ +G+ +D  +VD+WSLGV
Sbjct: 182 ENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGV 241

Query: 318 LCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
           + Y  + G  PF+    +E  +R+ R ++  P +++    +L+ R L  NP +R  L ++
Sbjct: 242 ILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQI 301

Query: 378 LEHPWITA 385
           ++  WI A
Sbjct: 302 MKDRWINA 309


>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
           sapiens]
          Length = 688

 Score =  171 bits (433), Expect = 1e-42
 Identities = 87/254 (34%), Positives = 147/254 (57%), Gaps = 3/254 (1%)

Query: 132 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 191
           ++ + R +GKG F  V LAR   +   +A+K++ K QL  + ++ +L REV I   L HP
Sbjct: 58  NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQ-KLFREVRIMKGLNHP 116

Query: 192 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKR 251
           NI++L+        +YL++EYA  G V+  L    +  E+       ++ +A+ YCH K 
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176

Query: 252 VIHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EK 309
           ++HRD+K ENLLL +   +KIADFG+S      S+  T CG+  Y  PE+ +G+ +D  +
Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 236

Query: 310 VDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPS 369
           VD+WSLGV+ Y  + G  PF+ +  +E  +R+ R ++  P +++     ++ R L  NP+
Sbjct: 237 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPA 296

Query: 370 QRPMLREVLEHPWI 383
           +R  L ++++  WI
Sbjct: 297 KRCTLEQIMKDKWI 310


>gi|239756427 PREDICTED: similar to 3-phosphoinositide dependent
           protein kinase-1 [Homo sapiens]
          Length = 471

 Score =  170 bits (431), Expect = 2e-42
 Identities = 103/334 (30%), Positives = 162/334 (48%), Gaps = 29/334 (8%)

Query: 43  QAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSV-PHPVSRPLNNTQKSKQP 101
           Q+  VLC   S   +  Q +       P  +++   +  T+  P P +  L + Q   QP
Sbjct: 34  QSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQP 93

Query: 102 LPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILAL 161
               PE                        DF+ G+ LG+G F  V LARE  +    A+
Sbjct: 94  RKKRPE------------------------DFKFGKILGEGSFSTVVLARELATSREYAI 129

Query: 162 KVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRE 221
           K+L K  + K      + RE ++ S L HP  ++LY  F    R+Y  L YA  G + + 
Sbjct: 130 KILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQTTRRLYFGLSYAKNGELLKY 189

Query: 222 LQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG----W 277
           ++K+  FDE  T  Y  E+ +AL Y H K +IHRD+KPEN+LL     ++I DFG     
Sbjct: 190 IRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL 249

Query: 278 SVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQET 337
           S  +  +R  +  GT  Y+ PE++  +   +  DLW+LG + Y+ + G PPF A      
Sbjct: 250 SPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLI 309

Query: 338 YKRISRVEFTFPDFVTEGARDLISRLLKHNPSQR 371
           +++I ++E+ FP+     ARDL+ +LL  + ++R
Sbjct: 310 FQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKR 343


>gi|150456432 unc-51-like kinase 3 [Homo sapiens]
          Length = 472

 Score =  169 bits (429), Expect = 3e-42
 Identities = 92/261 (35%), Positives = 155/261 (59%), Gaps = 8/261 (3%)

Query: 130 LEDFEIGRPLGKGKFGNVYLA-REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHL 188
           L+ F +   LG G +  VY A  +K ++ ++A+K + K  L KA VE+ L  E+EI   +
Sbjct: 11  LDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLT-EIEILKGI 69

Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
           RHP+I++L  +  D+  +YLI+E+   G + R +       E+    ++ +LA+AL + H
Sbjct: 70  RHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLH 129

Query: 249 SKRVIHRDIKPENLLLGSAGE--LKIADFGWSVH-APSSRRTTLCGTLDYLPPEMIEGRM 305
            + + H D+KP+N+LL S  +  LK+ADFG++ H +P   +  L G+  Y+ PEM+  R 
Sbjct: 130 ERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQ 189

Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISR---VEFTFPDFVTEGARDLISR 362
           +D +VDLWS+GV+ YE L G+PPF + ++ E  ++I     +E      ++   RDL+ R
Sbjct: 190 YDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLLQR 249

Query: 363 LLKHNPSQRPMLREVLEHPWI 383
           LL+ +PS+R   ++   HPW+
Sbjct: 250 LLERDPSRRISFQDFFAHPWV 270


>gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]
          Length = 1263

 Score =  169 bits (427), Expect = 5e-42
 Identities = 89/261 (34%), Positives = 147/261 (56%), Gaps = 3/261 (1%)

Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
           +EI R +GKG F  V  A    +K  +A+K++ K QL++  ++ ++ REV+I   L HP+
Sbjct: 8   YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLK-KIFREVQIMKMLCHPH 66

Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
           I+RLY        +YL+ EYA  G ++  L    +  E+       ++  A+ +CH + +
Sbjct: 67  IIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNI 126

Query: 253 IHRDIKPENLLLGSAGELKIADFGWS-VHAPSSRRTTLCGTLDYLPPEMIEGRMHD-EKV 310
           +HRD+K ENLLL +   +KIADFG+S +  P     T CG+  Y  PE+ EG+ +D  KV
Sbjct: 127 VHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKV 186

Query: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
           D+WSLGV+ Y  + G  PF+ +T Q    R+   +F  P F++     LI  +L  +P++
Sbjct: 187 DIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNK 246

Query: 371 RPMLREVLEHPWITANSSKPS 391
           R  + ++ +H W+    + P+
Sbjct: 247 RLSMEQICKHKWMKLGDADPN 267


>gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [Homo
           sapiens]
          Length = 482

 Score =  169 bits (427), Expect = 5e-42
 Identities = 95/246 (38%), Positives = 141/246 (57%), Gaps = 8/246 (3%)

Query: 133 FEIGRPLGKGKFGNVYLAREKQSKF---ILALKVLFKAQLEKAGVEH-QLRREVEIQSHL 188
           FE+ R LGKG +G V+  R+ Q      I A+KVL KA++ +   +    R E  I   +
Sbjct: 67  FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126

Query: 189 RHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
           +HP I+ L   F    ++YLILE    G ++  L++   F E     Y+ E+  AL + H
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186

Query: 249 SKRVIHRDIKPENLLLGSAGELKIADFGW---SVHAPSSRRTTLCGTLDYLPPEMIEGRM 305
           S+ +I+RD+KPEN++L S G +K+ DFG    S+H  +   T  CGT++Y+ PE++    
Sbjct: 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHT-FCGTIEYMAPEILVRSG 245

Query: 306 HDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLK 365
           H+  VD WSLG L Y+ L G PPF A   ++T  +I R +   P ++T  ARDL+ + LK
Sbjct: 246 HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLK 305

Query: 366 HNPSQR 371
            NPSQR
Sbjct: 306 RNPSQR 311


>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
           [Homo sapiens]
          Length = 709

 Score =  168 bits (425), Expect = 9e-42
 Identities = 92/297 (30%), Positives = 164/297 (55%), Gaps = 5/297 (1%)

Query: 91  PLNNTQKSKQPLPSAPENNPEEE--LASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVY 148
           P  N + ++QP     ++ P  +  +   + +  S   Q  + ++ + + +GKG F  V 
Sbjct: 9   PTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVK 68

Query: 149 LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYL 208
           LAR   +   +A+K++ K QL  + ++ +L REV I   L HPNI++L+        +YL
Sbjct: 69  LARHILTGKEVAVKIIDKTQLNSSSLQ-KLFREVRIMKVLNHPNIVKLFEVIETEKTLYL 127

Query: 209 ILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG 268
           ++EYA  G V+  L    +  E+       ++ +A+ YCH K ++HRD+K ENLLL +  
Sbjct: 128 VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADM 187

Query: 269 ELKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGVLCYEFLVGK 326
            +KIADFG+S      ++  T CG+  Y  PE+ +G+ +D  +VD+WSLGV+ Y  + G 
Sbjct: 188 NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 247

Query: 327 PPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
            PF+    +E  +R+ R ++  P +++    +L+ + L  NPS+R  L ++++  W+
Sbjct: 248 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304


>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
           [Homo sapiens]
          Length = 719

 Score =  168 bits (425), Expect = 9e-42
 Identities = 92/297 (30%), Positives = 164/297 (55%), Gaps = 5/297 (1%)

Query: 91  PLNNTQKSKQPLPSAPENNPEEE--LASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVY 148
           P  N + ++QP     ++ P  +  +   + +  S   Q  + ++ + + +GKG F  V 
Sbjct: 9   PTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVK 68

Query: 149 LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYL 208
           LAR   +   +A+K++ K QL  + ++ +L REV I   L HPNI++L+        +YL
Sbjct: 69  LARHILTGKEVAVKIIDKTQLNSSSLQ-KLFREVRIMKVLNHPNIVKLFEVIETEKTLYL 127

Query: 209 ILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG 268
           ++EYA  G V+  L    +  E+       ++ +A+ YCH K ++HRD+K ENLLL +  
Sbjct: 128 VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADM 187

Query: 269 ELKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGVLCYEFLVGK 326
            +KIADFG+S      ++  T CG+  Y  PE+ +G+ +D  +VD+WSLGV+ Y  + G 
Sbjct: 188 NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 247

Query: 327 PPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
            PF+    +E  +R+ R ++  P +++    +L+ + L  NPS+R  L ++++  W+
Sbjct: 248 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304


>gi|254028234 MAP/microtubule affinity-regulating kinase 2 isoform d
           [Homo sapiens]
          Length = 788

 Score =  168 bits (425), Expect = 9e-42
 Identities = 92/297 (30%), Positives = 164/297 (55%), Gaps = 5/297 (1%)

Query: 91  PLNNTQKSKQPLPSAPENNPEEE--LASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVY 148
           P  N + ++QP     ++ P  +  +   + +  S   Q  + ++ + + +GKG F  V 
Sbjct: 9   PTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVK 68

Query: 149 LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYL 208
           LAR   +   +A+K++ K QL  + ++ +L REV I   L HPNI++L+        +YL
Sbjct: 69  LARHILTGKEVAVKIIDKTQLNSSSLQ-KLFREVRIMKVLNHPNIVKLFEVIETEKTLYL 127

Query: 209 ILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG 268
           ++EYA  G V+  L    +  E+       ++ +A+ YCH K ++HRD+K ENLLL +  
Sbjct: 128 VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADM 187

Query: 269 ELKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGVLCYEFLVGK 326
            +KIADFG+S      ++  T CG+  Y  PE+ +G+ +D  +VD+WSLGV+ Y  + G 
Sbjct: 188 NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 247

Query: 327 PPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
            PF+    +E  +R+ R ++  P +++    +L+ + L  NPS+R  L ++++  W+
Sbjct: 248 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304


>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
           [Homo sapiens]
          Length = 724

 Score =  168 bits (425), Expect = 9e-42
 Identities = 92/297 (30%), Positives = 164/297 (55%), Gaps = 5/297 (1%)

Query: 91  PLNNTQKSKQPLPSAPENNPEEE--LASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVY 148
           P  N + ++QP     ++ P  +  +   + +  S   Q  + ++ + + +GKG F  V 
Sbjct: 9   PTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVK 68

Query: 149 LAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYL 208
           LAR   +   +A+K++ K QL  + ++ +L REV I   L HPNI++L+        +YL
Sbjct: 69  LARHILTGKEVAVKIIDKTQLNSSSLQ-KLFREVRIMKVLNHPNIVKLFEVIETEKTLYL 127

Query: 209 ILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAG 268
           ++EYA  G V+  L    +  E+       ++ +A+ YCH K ++HRD+K ENLLL +  
Sbjct: 128 VMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADM 187

Query: 269 ELKIADFGWSVHAP-SSRRTTLCGTLDYLPPEMIEGRMHD-EKVDLWSLGVLCYEFLVGK 326
            +KIADFG+S      ++  T CG+  Y  PE+ +G+ +D  +VD+WSLGV+ Y  + G 
Sbjct: 188 NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 247

Query: 327 PPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWI 383
            PF+    +E  +R+ R ++  P +++    +L+ + L  NPS+R  L ++++  W+
Sbjct: 248 LPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304


>gi|239745384 PREDICTED: hypothetical protein XP_002343452 [Homo
           sapiens]
          Length = 396

 Score =  167 bits (424), Expect = 1e-41
 Identities = 88/245 (35%), Positives = 138/245 (56%), Gaps = 4/245 (1%)

Query: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
           EDF+ G+ LG+G F  V LARE  +    A+K+L K  + K      + RE ++ S L H
Sbjct: 53  EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 112

Query: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250
           P  ++LY  F D  ++Y  L YA  G + + ++K+  FDE  T  Y  E+ +AL Y H K
Sbjct: 113 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 172

Query: 251 RVIHRDIKPENLLLGSAGELKIADFG----WSVHAPSSRRTTLCGTLDYLPPEMIEGRMH 306
            +IHRD+KPEN+LL     ++I DFG     S  +  +R  +  GT  Y+ PE++  +  
Sbjct: 173 GIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSA 232

Query: 307 DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKH 366
            +  DLW+LG + Y+ + G PPF A      +++I ++E+ FP+     ARDL+ +LL  
Sbjct: 233 CKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVL 292

Query: 367 NPSQR 371
           + ++R
Sbjct: 293 DATKR 297


>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
          Length = 926

 Score =  166 bits (421), Expect = 3e-41
 Identities = 87/253 (34%), Positives = 146/253 (57%), Gaps = 3/253 (1%)

Query: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
           ++I   LGKG F  V L R + +K  +A+K++ K+QL+   +E ++ REV+I   L HP+
Sbjct: 20  YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLE-KIYREVQIMKMLDHPH 78

Query: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252
           I++LY      + +YL+ EYA  G ++  L    + +E        ++ +A+ YCH +++
Sbjct: 79  IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138

Query: 253 IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR-RTTLCGTLDYLPPEMIEGRMHD-EKV 310
           +HRD+K ENLLL +   +KIADFG+     S     T CG+  Y  PE+ EG+ ++  ++
Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQL 198

Query: 311 DLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQ 370
           D+WS+GV+ Y  + G  PF+  T     +R+    F  P F++E    LI R+L  +PS+
Sbjct: 199 DIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK 258

Query: 371 RPMLREVLEHPWI 383
           R  + ++ EH W+
Sbjct: 259 RLTIAQIKEHKWM 271


>gi|4826948 protein kinase, X-linked [Homo sapiens]
          Length = 358

 Score =  166 bits (420), Expect = 3e-41
 Identities = 85/244 (34%), Positives = 139/244 (56%), Gaps = 1/244 (0%)

Query: 128 WALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSH 187
           ++L+DF+    +G G FG V+L +EK +K   ALKV+    + +   E  +  E  +   
Sbjct: 44  YSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKE 103

Query: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYC 247
           + HP ++RL+  +HD   +Y+++EY P G ++  L+   +F       Y  E+  A+ Y 
Sbjct: 104 VSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYL 163

Query: 248 HSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHD 307
           HSK +++RD+KPEN+LL   G +K+ DFG++      R  TLCGT +YL PE+I+ + H 
Sbjct: 164 HSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKL-VDRTWTLCGTPEYLAPEVIQSKGHG 222

Query: 308 EKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 367
             VD W+LG+L +E L G PPF  +     Y++I   +  FP  +    +DLI +LL  +
Sbjct: 223 RAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVD 282

Query: 368 PSQR 371
            ++R
Sbjct: 283 RTRR 286


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,429,709
Number of Sequences: 37866
Number of extensions: 791337
Number of successful extensions: 6286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 765
Number of HSP's successfully gapped in prelim test: 156
Number of HSP's that attempted gapping in prelim test: 3424
Number of HSP's gapped (non-prelim): 1231
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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