Guide to the Human Genome
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Name: PLK4 Sequence: fasta or formatted (970aa) NCBI GI: 121114283
Description:

polo-like kinase 4

Referenced in:

Additional Serine / Threonine Protein Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.1         49           2
 C cysteine            1.3         13           1
 D aspartate           4.6         45           1
 E glutamate           5.9         57           3
 F phenylalanine       3.8         37           2
 G glycine             5.6         54           3
 H histidine           2.9         28           1
 I isoleucine          5.4         52           3
 K lysine              6.8         66           2
 L leucine             7.8         76           3
 M methionine          2.7         26           1
 N asparagine          5.8         56           2
 P proline             5.5         53           3
 Q glutamine           4.1         40           2
 R arginine            4.9         48           2
 S serine             11.4        111           4
 T threonine           6.8         66           3
 V valine              4.8         47           2
 W tryptophan          0.9          9           1
 Y tyrosine            3.8         37           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   polo-like kinase 4 
PLK3                  0.105   polo-like kinase 3 
PLK2                  0.100   polo-like kinase 2 
PLK1                  0.093   polo-like kinase 1 
AURKA                 0.090   serine/threonine protein kinase 6 
AURKA                 0.090   serine/threonine protein kinase 6 
AURKA                 0.090   serine/threonine protein kinase 6 
AURKA                 0.090   serine/threonine protein kinase 6 
AURKA                 0.090   serine/threonine protein kinase 6 
AURKA                 0.090   serine/threonine protein kinase 6 
AURKB                 0.086   aurora kinase B 
AURKC                 0.081   aurora kinase C isoform 3 
AURKC                 0.081   aurora kinase C isoform 2 
AURKC                 0.081   aurora kinase C isoform 1 
NUAK1                 0.080   AMPK-related protein kinase 5 
MARK1                 0.074   MAP/microtubule affinity-regulating kinase 1 
QSK                   0.073   serine/threonine-protein kinase QSK 
MARK2                 0.073   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.073   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.073   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.073   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.073   MAP/microtubule affinity-regulating kinase 2 isoform...
MARK3                 0.073   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.073   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.073   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.073   MAP/microtubule affinity-regulating kinase 3 isoform...
MARK4                 0.073   MAP/microtubule affinity-regulating kinase 4 
PDPK1                 0.073   3-phosphoinositide dependent protein kinase-1 isoform...
LOC100287510          0.073   PREDICTED: hypothetical protein XP_002343452 
SIK2                  0.072   SNF1-like kinase 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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