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Search of human proteins with 38045938
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38045938 ring finger protein 144 [Homo sapiens]
(292 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38045938 ring finger protein 144 [Homo sapiens] 635 0.0
gi|50284696 IBR domain containing 2 [Homo sapiens] 353 1e-97
gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 113 2e-25
gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 111 9e-25
gi|35493801 ring finger protein 19 [Homo sapiens] 108 7e-24
gi|35493782 ring finger protein 19 [Homo sapiens] 108 7e-24
gi|5453557 ariadne homolog 2 [Homo sapiens] 101 9e-22
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 98 1e-20
gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 96 3e-20
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 96 3e-20
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 96 3e-20
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 96 3e-20
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 96 3e-20
gi|46370057 ring finger protein 216 isoform b [Homo sapiens] 83 2e-16
gi|46358403 ring finger protein 216 isoform a [Homo sapiens] 83 2e-16
gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa... 80 2e-15
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 77 2e-14
gi|109150431 ring finger protein 31 [Homo sapiens] 72 6e-13
gi|22749145 ring finger protein 217 [Homo sapiens] 69 6e-12
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 66 4e-11
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 66 4e-11
gi|169790973 parkin isoform 3 [Homo sapiens] 53 4e-07
gi|169790971 parkin isoform 2 [Homo sapiens] 53 4e-07
gi|169790969 parkin isoform 1 [Homo sapiens] 53 4e-07
gi|134288906 tripartite motif-containing 67 [Homo sapiens] 38 0.009
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 37 0.027
gi|31742478 ring finger protein 3 [Homo sapiens] 34 0.13
gi|22749189 zinc finger protein 645 [Homo sapiens] 34 0.17
gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a... 34 0.17
gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens] 33 0.23
>gi|38045938 ring finger protein 144 [Homo sapiens]
Length = 292
Score = 635 bits (1639), Expect = 0.0
Identities = 292/292 (100%), Positives = 292/292 (100%)
Query: 1 MTTTRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLE 60
MTTTRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLE
Sbjct: 1 MTTTRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLE 60
Query: 61 TAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVC 120
TAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVC
Sbjct: 61 TAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVC 120
Query: 121 QLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSAAFKMEEDDA 180
QLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSAAFKMEEDDA
Sbjct: 121 QLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSAAFKMEEDDA 180
Query: 181 PIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDKGPCRNKLGHSR 240
PIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDKGPCRNKLGHSR
Sbjct: 181 PIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDKGPCRNKLGHSR 240
Query: 241 ASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCSKGDDDPLPT 292
ASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCSKGDDDPLPT
Sbjct: 241 ASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCSKGDDDPLPT 292
>gi|50284696 IBR domain containing 2 [Homo sapiens]
Length = 303
Score = 353 bits (905), Expect = 1e-97
Identities = 161/286 (56%), Positives = 204/286 (71%), Gaps = 3/286 (1%)
Query: 1 MTTTRYRPT-WDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGL 59
+ T PT DLA PL++CKLCL E +++MTT+ +CQCIFCT CLKQY++L I+EG
Sbjct: 10 LAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGC 69
Query: 60 ETAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAV 119
+ I+CPD C G LQE EI C+V + Q Y++L+FEREV DP RTWCP + CQ V
Sbjct: 70 GSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTV 129
Query: 120 CQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSAAFKMEEDD 179
C + P V+C +C ++FCS CK +WH C ++ PI LP E A F + +
Sbjct: 130 CPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIV-LPTEHRALFGTDAE- 187
Query: 180 APIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDKGPCRNKLGHS 239
APIK+CP C+VYIER+EGCAQMMCKNCKH FCWYCL++LD+D L HYDKGPCRNKLGHS
Sbjct: 188 APIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHS 247
Query: 240 RASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCSKG 285
RASV+W+RTQVVGI G G++ LV SP LLLA+P ++CC CK +G
Sbjct: 248 RASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRG 293
>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
Length = 587
Score = 113 bits (283), Expect = 2e-25
Identities = 74/269 (27%), Positives = 111/269 (41%), Gaps = 22/269 (8%)
Query: 18 VSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQ 77
V C LCL P E+ + C C CL+ Y+ L I E ISCP+ + L
Sbjct: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPECS----ERLN 171
Query: 78 ENEIECMVA-AEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCK 136
++I ++A +M +Y++ R + DP WCPA C + +
Sbjct: 172 PHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCERE 231
Query: 137 ACRMEFCSTCKASWHPGQGC-----PETMPITFLPGETSA-AFKMEEDDAPIKRCPKCKV 190
C+ EFC CK WHP Q C + TS ++ E IK CP+C
Sbjct: 232 GCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSA 291
Query: 191 YIER--DEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHY-DKGPCR---NKLGHSRASVI 244
YI + D C M C C FCW C++ + D +HY C K + ++
Sbjct: 292 YIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD----LHYLSPSGCTFWGKKPWSRKKKIL 347
Query: 245 WHRTQVVGIFAGFGLLLLVASPFLLLATP 273
W ++G G L+ +A P +++ P
Sbjct: 348 WQLGTLIGAPVGISLIAGIAIPAMVIGIP 376
>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
Length = 732
Score = 111 bits (277), Expect = 9e-25
Identities = 75/270 (27%), Positives = 112/270 (41%), Gaps = 23/270 (8%)
Query: 18 VSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQ 77
V C LCL P E+ + C C CL+ Y+ L I E ISCP+ + L
Sbjct: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPECS----ERLN 171
Query: 78 ENEIECMVA-AEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCK 136
++I ++A +M +Y++ R + DP WCPA C + +
Sbjct: 172 PHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCERE 231
Query: 137 ACRMEFCSTCKASWHPGQGC-----PETMPITFLPGETSA-AFKMEEDDA-PIKRCPKCK 189
C+ EFC CK WHP Q C + TS ++ E A IK CP+C
Sbjct: 232 GCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCS 291
Query: 190 VYIER--DEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHY-DKGPCR---NKLGHSRASV 243
YI + D C M C C FCW C++ + D +HY C K + +
Sbjct: 292 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD----LHYLSPSGCTFWGKKPWSRKKKI 347
Query: 244 IWHRTQVVGIFAGFGLLLLVASPFLLLATP 273
+W ++G G L+ +A P +++ P
Sbjct: 348 LWQLGTLIGAPVGISLIAGIAIPAMVIGIP 377
>gi|35493801 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 108 bits (269), Expect = 7e-24
Identities = 76/274 (27%), Positives = 121/274 (44%), Gaps = 30/274 (10%)
Query: 18 VSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQ 77
+ C LCL + ++ I C C CL+QY+ + I E ISCP+ C ++
Sbjct: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISES-RVNISCPE--CTER--FN 184
Query: 78 ENEIECMVAAEI-MQRYKKLQFEREVLFDPCRTWCPASTC-QAVCQLQDVGLQTPQPVQC 135
++I +++ ++ M++Y++ R ++ DP WCPA C AV G + + C
Sbjct: 185 PHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF---GCASCPKLTC 241
Query: 136 --KACRMEFCSTCKASWHPGQGC-----PETMPITFLPGETSAAFKMEEDDA---PIKRC 185
+ C EFC CK WHP Q C + +S+ +E A IK C
Sbjct: 242 GREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPC 301
Query: 186 PKCKVYIER--DEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHY-DKGPCR---NKLGHS 239
P+C YI + D C M C C FCW C++ + D +HY C K
Sbjct: 302 PRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD----LHYLSPSGCTFWGKKPWSR 357
Query: 240 RASVIWHRTQVVGIFAGFGLLLLVASPFLLLATP 273
+ ++W +VG G L+ +A P +++ P
Sbjct: 358 KKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIP 391
>gi|35493782 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 108 bits (269), Expect = 7e-24
Identities = 76/274 (27%), Positives = 121/274 (44%), Gaps = 30/274 (10%)
Query: 18 VSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQ 77
+ C LCL + ++ I C C CL+QY+ + I E ISCP+ C ++
Sbjct: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISES-RVNISCPE--CTER--FN 184
Query: 78 ENEIECMVAAEI-MQRYKKLQFEREVLFDPCRTWCPASTC-QAVCQLQDVGLQTPQPVQC 135
++I +++ ++ M++Y++ R ++ DP WCPA C AV G + + C
Sbjct: 185 PHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF---GCASCPKLTC 241
Query: 136 --KACRMEFCSTCKASWHPGQGC-----PETMPITFLPGETSAAFKMEEDDA---PIKRC 185
+ C EFC CK WHP Q C + +S+ +E A IK C
Sbjct: 242 GREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPC 301
Query: 186 PKCKVYIER--DEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHY-DKGPCR---NKLGHS 239
P+C YI + D C M C C FCW C++ + D +HY C K
Sbjct: 302 PRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD----LHYLSPSGCTFWGKKPWSR 357
Query: 240 RASVIWHRTQVVGIFAGFGLLLLVASPFLLLATP 273
+ ++W +VG G L+ +A P +++ P
Sbjct: 358 KKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIP 391
>gi|5453557 ariadne homolog 2 [Homo sapiens]
Length = 493
Score = 101 bits (251), Expect = 9e-22
Identities = 57/197 (28%), Positives = 92/197 (46%), Gaps = 9/197 (4%)
Query: 20 CKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQEN 79
C +C+ E + ++A CQ FC C +Q+ +L+K+G+ +SC CP + ++
Sbjct: 139 CAVCMQFVRKENLLSLA-CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTP-EDF 196
Query: 80 EIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACR 139
+ E+ ++Y++ F V CP + C V ++Q+ + VQC C
Sbjct: 197 VFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQE---PRARRVQCNRCN 253
Query: 140 MEFCSTCKASWHPGQGCPETMP-ITFLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGC 198
FC C+ +H C +T ++ A + A K CPKC + IE++ GC
Sbjct: 254 EVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYIS---AHTKDCPKCNICIEKNGGC 310
Query: 199 AQMMCKNCKHAFCWYCL 215
M C CKH FCW CL
Sbjct: 311 NHMQCSKCKHDFCWMCL 327
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 97.8 bits (242), Expect = 1e-20
Identities = 69/224 (30%), Positives = 101/224 (45%), Gaps = 31/224 (13%)
Query: 4 TRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVEL-LIKEGLETA 62
TR T A D + C++C YP T + +C FC C +Y+ +++EG+
Sbjct: 172 TRQMNTRSSAQD--MPCQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQT 228
Query: 63 ISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQ 121
ISCP C + +N + ++ +++ +Y+ L V + WCPA C V +
Sbjct: 229 ISCPAHGCDIL--VDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVK 286
Query: 122 LQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSAAFKMEEDD-- 179
+Q +PV+CK C +FC C +WH C K +DD
Sbjct: 287 VQ---YPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWL----------KKWIKKCDDDSE 332
Query: 180 ------APIKRCPKCKVYIERDEGCAQMMCK--NCKHAFCWYCL 215
A K CPKC V IE+D GC M+C+ NCK FCW CL
Sbjct: 333 TSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCL 376
>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 96.3 bits (238), Expect = 3e-20
Identities = 63/247 (25%), Positives = 105/247 (42%), Gaps = 33/247 (13%)
Query: 17 LVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHL 76
L C +C E + +C+ ++C CLK Y E+ I++G ++CP+ CP
Sbjct: 217 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVA-- 274
Query: 77 QENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCK 136
+++ +V AE+ RY +L + + +CP CQ + +Q+ G C
Sbjct: 275 TPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ-LPVMQEPGCTMG---ICS 330
Query: 137 ACRMEFCSTCKASWHPGQGCPET------MPITFLPGETS----------------AAFK 174
+C FC+ C+ ++H C T + +L + + A +
Sbjct: 331 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 390
Query: 175 MEED---DAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDK-- 229
ME + K CP C IE+ +GC +M C C FCW C+ SL H++
Sbjct: 391 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 450
Query: 230 GPCRNKL 236
PC N+L
Sbjct: 451 SPCFNRL 457
Score = 28.9 bits (63), Expect = 5.6
Identities = 30/141 (21%), Positives = 51/141 (36%), Gaps = 11/141 (7%)
Query: 11 DLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETA-ISCPDAA 69
D+ P C+L + + P M + C FCTLC Y G+ ++
Sbjct: 305 DVVYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTY------HGVSPCKVTAEKLM 358
Query: 70 CPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDV-GLQ 128
+ +LQ +E + + QRY K ++ + + W ++ C + L
Sbjct: 359 DLRNEYLQADEANKRL---LDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLD 415
Query: 129 TPQPVQCKACRMEFCSTCKAS 149
+ C C FC C S
Sbjct: 416 GCNKMTCTGCMQYFCWICMGS 436
>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 96.3 bits (238), Expect = 3e-20
Identities = 63/247 (25%), Positives = 105/247 (42%), Gaps = 33/247 (13%)
Query: 17 LVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHL 76
L C +C E + +C+ ++C CLK Y E+ I++G ++CP+ CP
Sbjct: 217 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVA-- 274
Query: 77 QENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCK 136
+++ +V AE+ RY +L + + +CP CQ + +Q+ G C
Sbjct: 275 TPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ-LPVMQEPGCTMG---ICS 330
Query: 137 ACRMEFCSTCKASWHPGQGCPET------MPITFLPGETS----------------AAFK 174
+C FC+ C+ ++H C T + +L + + A +
Sbjct: 331 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 390
Query: 175 MEED---DAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDK-- 229
ME + K CP C IE+ +GC +M C C FCW C+ SL H++
Sbjct: 391 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 450
Query: 230 GPCRNKL 236
PC N+L
Sbjct: 451 SPCFNRL 457
Score = 28.9 bits (63), Expect = 5.6
Identities = 30/141 (21%), Positives = 51/141 (36%), Gaps = 11/141 (7%)
Query: 11 DLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETA-ISCPDAA 69
D+ P C+L + + P M + C FCTLC Y G+ ++
Sbjct: 305 DVVYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTY------HGVSPCKVTAEKLM 358
Query: 70 CPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDV-GLQ 128
+ +LQ +E + + QRY K ++ + + W ++ C + L
Sbjct: 359 DLRNEYLQADEANKRL---LDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLD 415
Query: 129 TPQPVQCKACRMEFCSTCKAS 149
+ C C FC C S
Sbjct: 416 GCNKMTCTGCMQYFCWICMGS 436
>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 96.3 bits (238), Expect = 3e-20
Identities = 63/247 (25%), Positives = 105/247 (42%), Gaps = 33/247 (13%)
Query: 17 LVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHL 76
L C +C E + +C+ ++C CLK Y E+ I++G ++CP+ CP
Sbjct: 217 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVA-- 274
Query: 77 QENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCK 136
+++ +V AE+ RY +L + + +CP CQ + +Q+ G C
Sbjct: 275 TPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ-LPVMQEPGCTMG---ICS 330
Query: 137 ACRMEFCSTCKASWHPGQGCPET------MPITFLPGETS----------------AAFK 174
+C FC+ C+ ++H C T + +L + + A +
Sbjct: 331 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 390
Query: 175 MEED---DAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDK-- 229
ME + K CP C IE+ +GC +M C C FCW C+ SL H++
Sbjct: 391 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 450
Query: 230 GPCRNKL 236
PC N+L
Sbjct: 451 SPCFNRL 457
Score = 28.9 bits (63), Expect = 5.6
Identities = 30/141 (21%), Positives = 51/141 (36%), Gaps = 11/141 (7%)
Query: 11 DLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETA-ISCPDAA 69
D+ P C+L + + P M + C FCTLC Y G+ ++
Sbjct: 305 DVVYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTY------HGVSPCKVTAEKLM 358
Query: 70 CPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDV-GLQ 128
+ +LQ +E + + QRY K ++ + + W ++ C + L
Sbjct: 359 DLRNEYLQADEANKRL---LDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLD 415
Query: 129 TPQPVQCKACRMEFCSTCKAS 149
+ C C FC C S
Sbjct: 416 GCNKMTCTGCMQYFCWICMGS 436
>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
Length = 348
Score = 96.3 bits (238), Expect = 3e-20
Identities = 63/247 (25%), Positives = 105/247 (42%), Gaps = 33/247 (13%)
Query: 17 LVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHL 76
L C +C E + +C+ ++C CLK Y E+ I++G ++CP+ CP
Sbjct: 91 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVA-- 148
Query: 77 QENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCK 136
+++ +V AE+ RY +L + + +CP CQ + +Q+ G C
Sbjct: 149 TPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ-LPVMQEPGCTMG---ICS 204
Query: 137 ACRMEFCSTCKASWHPGQGCPET------MPITFLPGETS----------------AAFK 174
+C FC+ C+ ++H C T + +L + + A +
Sbjct: 205 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 264
Query: 175 MEED---DAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDK-- 229
ME + K CP C IE+ +GC +M C C FCW C+ SL H++
Sbjct: 265 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 324
Query: 230 GPCRNKL 236
PC N+L
Sbjct: 325 SPCFNRL 331
Score = 28.9 bits (63), Expect = 5.6
Identities = 30/141 (21%), Positives = 51/141 (36%), Gaps = 11/141 (7%)
Query: 11 DLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETA-ISCPDAA 69
D+ P C+L + + P M + C FCTLC Y G+ ++
Sbjct: 179 DVVYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTY------HGVSPCKVTAEKLM 232
Query: 70 CPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDV-GLQ 128
+ +LQ +E + + QRY K ++ + + W ++ C + L
Sbjct: 233 DLRNEYLQADEANKRL---LDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLD 289
Query: 129 TPQPVQCKACRMEFCSTCKAS 149
+ C C FC C S
Sbjct: 290 GCNKMTCTGCMQYFCWICMGS 310
>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 96.3 bits (238), Expect = 3e-20
Identities = 63/247 (25%), Positives = 105/247 (42%), Gaps = 33/247 (13%)
Query: 17 LVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHL 76
L C +C E + +C+ ++C CLK Y E+ I++G ++CP+ CP
Sbjct: 217 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVA-- 274
Query: 77 QENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCK 136
+++ +V AE+ RY +L + + +CP CQ + +Q+ G C
Sbjct: 275 TPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQ-LPVMQEPGCTMG---ICS 330
Query: 137 ACRMEFCSTCKASWHPGQGCPET------MPITFLPGETS----------------AAFK 174
+C FC+ C+ ++H C T + +L + + A +
Sbjct: 331 SCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEE 390
Query: 175 MEED---DAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDK-- 229
ME + K CP C IE+ +GC +M C C FCW C+ SL H++
Sbjct: 391 MESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPG 450
Query: 230 GPCRNKL 236
PC N+L
Sbjct: 451 SPCFNRL 457
Score = 28.9 bits (63), Expect = 5.6
Identities = 30/141 (21%), Positives = 51/141 (36%), Gaps = 11/141 (7%)
Query: 11 DLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETA-ISCPDAA 69
D+ P C+L + + P M + C FCTLC Y G+ ++
Sbjct: 305 DVVYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTY------HGVSPCKVTAEKLM 358
Query: 70 CPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDV-GLQ 128
+ +LQ +E + + QRY K ++ + + W ++ C + L
Sbjct: 359 DLRNEYLQADEANKRL---LDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLD 415
Query: 129 TPQPVQCKACRMEFCSTCKAS 149
+ C C FC C S
Sbjct: 416 GCNKMTCTGCMQYFCWICMGS 436
>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
Length = 866
Score = 83.2 bits (204), Expect = 2e-16
Identities = 57/207 (27%), Positives = 93/207 (44%), Gaps = 14/207 (6%)
Query: 17 LVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHL 76
L+ C+ C GE+P E++T A +FC CL +Y + + + +SC + +C
Sbjct: 512 LIECRCCYGEFPFEELTQCADAH-LFCKECLIRYAQEAVFGSGKLELSCMEGSCTCS--F 568
Query: 77 QENEIECMVAAEIMQRYKKLQFEREV--LFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQ 134
+E+E ++ I+ +Y + + E EV + CP+ + A+ P P
Sbjct: 569 PTSELEKVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNP-- 626
Query: 135 CKACRMEFCSTCKASW--HPGQGCPETMPITFLPGETSAAFKMEEDDAPIKRCPKCKVYI 192
CR E C C+ W H G C E + TS KM A I++C KC +
Sbjct: 627 --HCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTA--ARIRKCHKCGTGL 682
Query: 193 ERDEGCAQMMCKNCKHAFCWYCLESLD 219
+ EGC +M C+ C C+ C S++
Sbjct: 683 IKSEGCNRMSCR-CGAQMCYLCRVSIN 708
>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
Length = 923
Score = 83.2 bits (204), Expect = 2e-16
Identities = 57/207 (27%), Positives = 93/207 (44%), Gaps = 14/207 (6%)
Query: 17 LVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHL 76
L+ C+ C GE+P E++T A +FC CL +Y + + + +SC + +C
Sbjct: 569 LIECRCCYGEFPFEELTQCADAH-LFCKECLIRYAQEAVFGSGKLELSCMEGSCTCS--F 625
Query: 77 QENEIECMVAAEIMQRYKKLQFEREV--LFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQ 134
+E+E ++ I+ +Y + + E EV + CP+ + A+ P P
Sbjct: 626 PTSELEKVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNP-- 683
Query: 135 CKACRMEFCSTCKASW--HPGQGCPETMPITFLPGETSAAFKMEEDDAPIKRCPKCKVYI 192
CR E C C+ W H G C E + TS KM A I++C KC +
Sbjct: 684 --HCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTA--ARIRKCHKCGTGL 739
Query: 193 ERDEGCAQMMCKNCKHAFCWYCLESLD 219
+ EGC +M C+ C C+ C S++
Sbjct: 740 IKSEGCNRMSCR-CGAQMCYLCRVSIN 765
>gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo
sapiens]
Length = 1089
Score = 80.5 bits (197), Expect = 2e-15
Identities = 63/230 (27%), Positives = 90/230 (39%), Gaps = 32/230 (13%)
Query: 11 DLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAAC 70
D +L + C + + E PV+ C FC C + ++ L I+EG I CP C
Sbjct: 329 DTSLCDICMCSISVFEDPVDM-----PCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDC 383
Query: 71 PKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTP 130
+ + + IE +V+ E+ +RY + + V +P WCP C +L G T
Sbjct: 384 FQL--VPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTS 441
Query: 131 ------------QPVQCKACRMEFCSTCKASWHPGQGCPE----TMPITFLPGETSAAFK 174
V C + FC C H C IT + E
Sbjct: 442 GSDTLSFPLLRAPAVDCGKGHL-FCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVS 500
Query: 175 MEEDDAP--------IKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLE 216
+DA K C CK I+++EGC M C CK+ FCW CLE
Sbjct: 501 EAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICLE 550
>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
sapiens]
Length = 2517
Score = 76.6 bits (187), Expect = 2e-14
Identities = 55/205 (26%), Positives = 78/205 (38%), Gaps = 13/205 (6%)
Query: 20 CKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQEN 79
C +C+ + C C C +Y+ I++ L +CP A CP Q
Sbjct: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQP--TGA 2127
Query: 80 EIECMVAA-EIMQRYKKLQFEREVLFDPCRTWCP-ASTCQAVCQLQDVGLQTPQPVQCKA 137
I +V++ E++ +Y+K V TWC C + Q +G T C
Sbjct: 2128 FIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTT----CSK 2183
Query: 138 CRMEFCSTCK-ASWHPGQGCPETMPIT----FLPGETSAAFKMEEDDAPIKRCPKCKVYI 192
C C C H C + G + A KRCP C+ I
Sbjct: 2184 CGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPI 2243
Query: 193 ERDEGCAQMMCKNCKHAFCWYCLES 217
E++EGC M C C H FCW CL+S
Sbjct: 2244 EKNEGCLHMTCAKCNHGFCWRCLKS 2268
>gi|109150431 ring finger protein 31 [Homo sapiens]
Length = 1072
Score = 72.0 bits (175), Expect = 6e-13
Identities = 53/212 (25%), Positives = 79/212 (37%), Gaps = 26/212 (12%)
Query: 20 CKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQEN 79
C +C P +M + C+C C C +Q+ + +KE T + CP AC + +
Sbjct: 699 CAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCP--ACGRPDLTDDT 756
Query: 80 EIECMVAAEIMQRYKKLQFEREVLF-----------DPCRTWCPASTCQAVCQLQDVGLQ 128
++ + +Q + L+ + LF DP WC A C + +
Sbjct: 757 QLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWC------AQCSFGFIYER 810
Query: 129 TPQPVQCKACRMEFCSTCKASW---HPGQGCPETMPITFL--PGETSAAFKMEEDDAPIK 183
C C FC CK W H G+ C + + P + M + I
Sbjct: 811 EQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGID 870
Query: 184 RCPKCKV-YIERDEGCAQMMCKNCKHAFCWYC 214
CPKCK Y GC C C+H FC C
Sbjct: 871 -CPKCKFSYALARGGCMHFHCTQCRHQFCSGC 901
Score = 31.2 bits (69), Expect = 1.1
Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 40/139 (28%)
Query: 27 YPVEQM-TTIAQCQCIFCTLCLKQYVEL---LIKEGLETAISCPDAACPKQG---HLQEN 79
Y EQ+ T QC FC C +Q+ E E + D QG +LQEN
Sbjct: 808 YEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQEN 867
Query: 80 EIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACR 139
I+C K +F + C + C CR
Sbjct: 868 GIDC----------PKCKFSYALARGGCMHF-----------------------HCTQCR 894
Query: 140 MEFCSTCKASWHPGQGCPE 158
+FCS C +++ CPE
Sbjct: 895 HQFCSGCYNAFYAKNKCPE 913
>gi|22749145 ring finger protein 217 [Homo sapiens]
Length = 275
Score = 68.6 bits (166), Expect = 6e-12
Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 8/87 (9%)
Query: 133 VQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSA---AFKMEEDDAPIKRCPKCK 189
+QC C+ +C C + WH G C E + G+ A ++E ++CPKCK
Sbjct: 81 IQCPTCQFVWCFKCHSPWHEGVNCKE-----YKKGDKLLRHWASEIEHGQRNAQKCPKCK 135
Query: 190 VYIERDEGCAQMMCKNCKHAFCWYCLE 216
++I+R EGC M C C FC+ C E
Sbjct: 136 IHIQRTEGCDHMTCSQCNTNFCYRCGE 162
Score = 30.0 bits (66), Expect = 2.5
Identities = 27/104 (25%), Positives = 40/104 (38%), Gaps = 18/104 (17%)
Query: 158 ETMPITFLPGETSAAFK----MEEDDAPIKRCPKCKVYI-----------ERDEGCAQMM 202
ET + L E S +K + D+ K CP+CK + R E ++
Sbjct: 23 ETTVVYNLTHEDSIKYKYFLELGRIDSSTKPCPQCKHFTTFKKKGHIPTPSRSESKYKIQ 82
Query: 203 CKNCKHAFCWYCLESLDDDFLLIHYDKGPCRNKLGHSRASVIWH 246
C C+ +C+ C + Y KG +KL AS I H
Sbjct: 83 CPTCQFVWCFKCHSPWHEGVNCKEYKKG---DKLLRHWASEIEH 123
>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
isoform 1 [Homo sapiens]
Length = 468
Score = 65.9 bits (159), Expect = 4e-11
Identities = 48/202 (23%), Positives = 71/202 (35%), Gaps = 18/202 (8%)
Query: 20 CKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCP--DAACPKQGHLQ 77
C +C + + +C FC CL+ I+ E +SCP D G L
Sbjct: 240 CPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPFIDNTYSCSGKLL 295
Query: 78 ENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKA 137
E EI+ ++ E QR+ L C C+ C +D C
Sbjct: 296 EREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED----DVNEFTCPV 351
Query: 138 CRMEFCSTCKASWHPGQGCPETMPITFLPGETSAA-------FKMEEDDAPIKRCPKCKV 190
C C CKA H C E L + A K+ RCP+C++
Sbjct: 352 CFHVNCLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQI 410
Query: 191 YIERDEGCAQMMCKNCKHAFCW 212
+++ +GC + C C CW
Sbjct: 411 VVQKKDGCDWIRCTVCHTEICW 432
>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
isoform 2 [Homo sapiens]
Length = 510
Score = 65.9 bits (159), Expect = 4e-11
Identities = 48/202 (23%), Positives = 71/202 (35%), Gaps = 18/202 (8%)
Query: 20 CKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCP--DAACPKQGHLQ 77
C +C + + +C FC CL+ I+ E +SCP D G L
Sbjct: 282 CPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPFIDNTYSCSGKLL 337
Query: 78 ENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKA 137
E EI+ ++ E QR+ L C C+ C +D C
Sbjct: 338 EREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED----DVNEFTCPV 393
Query: 138 CRMEFCSTCKASWHPGQGCPETMPITFLPGETSAA-------FKMEEDDAPIKRCPKCKV 190
C C CKA H C E L + A K+ RCP+C++
Sbjct: 394 CFHVNCLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQI 452
Query: 191 YIERDEGCAQMMCKNCKHAFCW 212
+++ +GC + C C CW
Sbjct: 453 VVQKKDGCDWIRCTVCHTEICW 474
>gi|169790973 parkin isoform 3 [Homo sapiens]
Length = 316
Score = 52.8 bits (125), Expect = 4e-07
Identities = 51/206 (24%), Positives = 81/206 (39%), Gaps = 48/206 (23%)
Query: 38 CQCIFCTLCL--KQYV-ELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAEIMQRYK 94
C ++C L +Q+V + + L CP++ + H + ++ E RY+
Sbjct: 114 CFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFR------ILGEEQYNRYQ 167
Query: 95 KLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKA---------CRMEFCST 145
+ E E + CP C A GL P+P Q K C FC
Sbjct: 168 QYGAE-ECVLQMGGVLCPRPGCGA-------GL-LPEPDQRKVTCEGGNGLGCGFAFCRE 218
Query: 146 CKASWHPGQGCPETMPITFLPGETSAAFKMEEDDAP---------------IKRCPKCKV 190
CK ++H G E + G T+ A++++E A K CP+C V
Sbjct: 219 CKEAYHEG----ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHV 274
Query: 191 YIERDEGCAQMMC--KNCKHAFCWYC 214
+E++ GC M C C+ +CW C
Sbjct: 275 PVEKNGGCMHMKCPQPQCRLEWCWNC 300
>gi|169790971 parkin isoform 2 [Homo sapiens]
Length = 437
Score = 52.8 bits (125), Expect = 4e-07
Identities = 51/206 (24%), Positives = 81/206 (39%), Gaps = 48/206 (23%)
Query: 38 CQCIFCTLCL--KQYV-ELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAEIMQRYK 94
C ++C L +Q+V + + L CP++ + H + ++ E RY+
Sbjct: 235 CFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFR------ILGEEQYNRYQ 288
Query: 95 KLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKA---------CRMEFCST 145
+ E E + CP C A GL P+P Q K C FC
Sbjct: 289 QYGAE-ECVLQMGGVLCPRPGCGA-------GL-LPEPDQRKVTCEGGNGLGCGFAFCRE 339
Query: 146 CKASWHPGQGCPETMPITFLPGETSAAFKMEEDDAP---------------IKRCPKCKV 190
CK ++H G E + G T+ A++++E A K CP+C V
Sbjct: 340 CKEAYHEG----ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHV 395
Query: 191 YIERDEGCAQMMC--KNCKHAFCWYC 214
+E++ GC M C C+ +CW C
Sbjct: 396 PVEKNGGCMHMKCPQPQCRLEWCWNC 421
>gi|169790969 parkin isoform 1 [Homo sapiens]
Length = 465
Score = 52.8 bits (125), Expect = 4e-07
Identities = 51/206 (24%), Positives = 81/206 (39%), Gaps = 48/206 (23%)
Query: 38 CQCIFCTLCL--KQYV-ELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAEIMQRYK 94
C ++C L +Q+V + + L CP++ + H + ++ E RY+
Sbjct: 263 CFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFR------ILGEEQYNRYQ 316
Query: 95 KLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKA---------CRMEFCST 145
+ E E + CP C A GL P+P Q K C FC
Sbjct: 317 QYGAE-ECVLQMGGVLCPRPGCGA-------GL-LPEPDQRKVTCEGGNGLGCGFAFCRE 367
Query: 146 CKASWHPGQGCPETMPITFLPGETSAAFKMEEDDAP---------------IKRCPKCKV 190
CK ++H G E + G T+ A++++E A K CP+C V
Sbjct: 368 CKEAYHEG----ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHV 423
Query: 191 YIERDEGCAQMMC--KNCKHAFCWYC 214
+E++ GC M C C+ +CW C
Sbjct: 424 PVEKNGGCMHMKCPQPQCRLEWCWNC 449
>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
Length = 783
Score = 38.1 bits (87), Expect = 0.009
Identities = 31/131 (23%), Positives = 43/131 (32%), Gaps = 30/131 (22%)
Query: 113 ASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQG-----------CPETMP 161
A+ A+CQL D P C+ C + +CS C+ HP +G P P
Sbjct: 201 AAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPPPP 260
Query: 162 ITFLPGETSAAFKMEEDDAPIK----------------RCPKCKVYIERDEGCAQMMCKN 205
G T A K + P C E + M C +
Sbjct: 261 AEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCP---EHEMENYSMYCVS 317
Query: 206 CKHAFCWYCLE 216
C+ C+ CLE
Sbjct: 318 CRTPVCYLCLE 328
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 36.6 bits (83), Expect = 0.027
Identities = 34/130 (26%), Positives = 51/130 (39%), Gaps = 17/130 (13%)
Query: 18 VSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGH-- 75
+SC +CL + E +TT C FC CL E +G + CP Q
Sbjct: 11 LSCSICLEPFK-EPVTT--PCGHNFCGSCLN---ETWAVQG--SPYLCPQCRAVYQARPQ 62
Query: 76 LQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQ--LQDVGLQTPQPV 133
L +N + C V + +Q + +V P R P+ Q C L++ ++T
Sbjct: 63 LHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKT---- 118
Query: 134 QCKACRMEFC 143
C C FC
Sbjct: 119 -CLVCMASFC 127
>gi|31742478 ring finger protein 3 [Homo sapiens]
Length = 242
Score = 34.3 bits (77), Expect = 0.13
Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 4/49 (8%)
Query: 4 TRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVE 52
TR WD+ + ++C+LC G Y ++ TT+ +C FC CL +Y+E
Sbjct: 3 TRKIKLWDI--NAHITCRLCSG-YLIDA-TTVTECLHTFCRSCLVKYLE 47
>gi|22749189 zinc finger protein 645 [Homo sapiens]
Length = 425
Score = 33.9 bits (76), Expect = 0.17
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 5/44 (11%)
Query: 176 EEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLD 219
E+DD PI C KC + I+ CKHAFC++C D
Sbjct: 48 EKDDLPIHFCDKCDLPIK-----IYGRIIPCKHAFCYHCANLYD 86
>gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a
[Homo sapiens]
Length = 410
Score = 33.9 bits (76), Expect = 0.17
Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 22/96 (22%)
Query: 166 PGETSAAFKMEEDDAPIKRCPKCK-VYIERDEG----CAQ-----------MMCKNCKHA 209
PG +SA K + RC C+ ++ R +G CA+ + C C +
Sbjct: 278 PGPSSAPAKASPEAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAES 337
Query: 210 FCWYCLESLDDDFLLIHYDKGPCRNKLGHSRASVIW 245
++CL + DF PC + GH R + W
Sbjct: 338 LLYHCLSDAEGDF------SDPCACEPGHPRPAARW 367
>gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens]
Length = 326
Score = 33.5 bits (75), Expect = 0.23
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 15/73 (20%)
Query: 3 TTRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETA 62
TTR + T L+P + C LC G Y ++ TTI +C FC C+ +Y LET+
Sbjct: 4 TTRIKIT---ELNPHLMCVLC-GGYFIDA-TTIIECLHSFCKTCIVRY--------LETS 50
Query: 63 ISCPDAACPKQGH 75
CP C Q H
Sbjct: 51 KYCP--ICDVQVH 61
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.479
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,069,149
Number of Sequences: 37866
Number of extensions: 623315
Number of successful extensions: 2617
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 2422
Number of HSP's gapped (non-prelim): 193
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.