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Search of human proteins with 37694062
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37694062 aquaporin 1 [Homo sapiens]
(269 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37694062 aquaporin 1 [Homo sapiens] 528 e-150
gi|6912506 major intrinsic protein of lens fiber [Homo sapiens] 233 2e-61
gi|4502179 aquaporin 2 [Homo sapiens] 230 9e-61
gi|4502183 aquaporin 5 [Homo sapiens] 224 8e-59
gi|4755125 aquaporin 4 isoform b [Homo sapiens] 216 2e-56
gi|4502181 aquaporin 4 isoform a [Homo sapiens] 216 2e-56
gi|86792455 aquaporin 6 [Homo sapiens] 202 2e-52
gi|45446752 aquaporin 8 [Homo sapiens] 99 4e-21
gi|4826645 aquaporin 3 [Homo sapiens] 77 1e-14
gi|157266307 aquaporin 9 [Homo sapiens] 77 2e-14
gi|22538420 aquaporin 10 [Homo sapiens] 65 6e-11
gi|4502187 aquaporin 7 [Homo sapiens] 65 8e-11
gi|40538880 aquaporin 12A [Homo sapiens] 35 0.069
gi|156447037 aquaporin 12B [Homo sapiens] 34 0.15
gi|194272186 enhancer of polycomb homolog 2 [Homo sapiens] 33 0.26
gi|156151386 hypothetical protein LOC80157 [Homo sapiens] 32 0.76
gi|42475555 monocarboxylate transporter 13 [Homo sapiens] 30 2.9
gi|16306483 solute carrier family 26, member 7 isoform a [Homo s... 30 2.9
gi|20336282 solute carrier family 26, member 7 isoform b [Homo s... 30 2.9
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 29 4.9
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 29 4.9
gi|154937330 sodium-dependent glucose transporter 1 [Homo sapiens] 28 8.4
>gi|37694062 aquaporin 1 [Homo sapiens]
Length = 269
Score = 528 bits (1359), Expect = e-150
Identities = 269/269 (100%), Positives = 269/269 (100%)
Query: 1 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI 60
MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI
Sbjct: 1 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI 60
Query: 61 ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT 120
ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT
Sbjct: 61 ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT 120
Query: 121 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH 180
GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH
Sbjct: 121 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH 180
Query: 181 LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD 240
LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD
Sbjct: 181 LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD 240
Query: 241 RVKVWTSGQVEEYDLDADDINSRVEMKPK 269
RVKVWTSGQVEEYDLDADDINSRVEMKPK
Sbjct: 241 RVKVWTSGQVEEYDLDADDINSRVEMKPK 269
>gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]
Length = 263
Score = 233 bits (593), Expect = 2e-61
Identities = 116/241 (48%), Positives = 157/241 (65%), Gaps = 7/241 (2%)
Query: 4 EFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATL 63
E + FWRA+ AEF AT +VF +GS+L ++ G ++V++AFGL++ATL
Sbjct: 3 ELRSASFWRAIFAEFFATLFYVFFGLGSSL--RWAPGPLHV-----LQVAMAFGLALATL 55
Query: 64 AQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNS 123
QSVGHISGAH+NPAVT L+ Q+S+ RA Y+ AQ +GA+ A+L +T +
Sbjct: 56 VQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAVRGN 115
Query: 124 LGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLA 183
L N L V+ GQ +EI TLQ VLC+ AT D RR GS LA+G S+ALGHL
Sbjct: 116 LALNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFG 175
Query: 184 IDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVK 243
+ YTG G+NPARSF A++T NF+NHW++WVGP IGG L L+YDF+L PR +++R+
Sbjct: 176 MYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISERLS 235
Query: 244 V 244
V
Sbjct: 236 V 236
>gi|4502179 aquaporin 2 [Homo sapiens]
Length = 271
Score = 230 bits (587), Expect = 9e-61
Identities = 114/241 (47%), Positives = 159/241 (65%), Gaps = 7/241 (2%)
Query: 4 EFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATL 63
E + F RAV AEFLAT LFVF +GSAL N A+ +++++AFGL I TL
Sbjct: 3 ELRSIAFSRAVFAEFLATLLFVFFGLGSAL-------NWPQALPSVLQIAMAFGLGIGTL 55
Query: 64 AQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNS 123
Q++GHISGAH+NPAVT+ L+ C +S+ RA Y+ AQ +GA+ A+L IT +
Sbjct: 56 VQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGD 115
Query: 124 LGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLA 183
L N L++ +GQ + +E+ TLQLVLC+ A+TD RR + G+ L+IG SVALGHLL
Sbjct: 116 LAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLG 175
Query: 184 IDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVK 243
I YTGC +NPARS AV+T F +HW+FW+GP +G L L+Y+++L P + L++R+
Sbjct: 176 IHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLA 235
Query: 244 V 244
V
Sbjct: 236 V 236
>gi|4502183 aquaporin 5 [Homo sapiens]
Length = 265
Score = 224 bits (570), Expect = 8e-59
Identities = 124/268 (46%), Positives = 167/268 (62%), Gaps = 12/268 (4%)
Query: 1 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI 60
M E F +AV AEFLAT +FVF +GSAL K+P +A+ ++++LAFGL+I
Sbjct: 1 MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSAL--KWP-----SALPTILQIALAFGLAI 53
Query: 61 ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT 120
TLAQ++G +SG H+NPA+TL LL+ QIS+ RA Y+ AQ VGAI IL G+
Sbjct: 54 GTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNA 113
Query: 121 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH 180
+L N L + GQ + +E+I T QL LC+ A+TD RR GS L+IGLSV LGH
Sbjct: 114 RGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGH 173
Query: 181 LLAIDYTGCGINPARSFGSAVITHNFS-NHWIFWVGPFIGGALAVLIYDFILAPRSSDLT 239
L+ I +TGC +NPARSFG AV+ + FS HW+FWVGP +G LA ++Y ++L P S L+
Sbjct: 174 LVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLS 233
Query: 240 DRVKVWTSGQVEEYDLDADDINSRVEMK 267
+RV + Y+ D D R E K
Sbjct: 234 ERVAIIKG----TYEPDEDWEEQREERK 257
>gi|4755125 aquaporin 4 isoform b [Homo sapiens]
Length = 301
Score = 216 bits (550), Expect = 2e-56
Identities = 109/224 (48%), Positives = 148/224 (66%), Gaps = 3/224 (1%)
Query: 10 FWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGH 69
FW+AV AEFLA +FV +S+GS + + G + D V +SL FGLSIAT+ Q GH
Sbjct: 12 FWKAVTAEFLAMLIFVLLSLGSTINWG---GTEKPLPVDMVLISLCFGLSIATMVQCFGH 68
Query: 70 ISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDL 129
ISG H+NPAVT+ ++ + +ISI +++ YI AQC+GAI+ IL +T LG +
Sbjct: 69 ISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMV 128
Query: 130 ADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGC 189
+ +G GL +E+I T QLV + A+ D +R D+ GS LAIG SVA+GHL AI+YTG
Sbjct: 129 HGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGA 188
Query: 190 GINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAP 233
+NPARSFG AVI N+ NHWI+WVGP IG LA +Y+++ P
Sbjct: 189 SMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCP 232
>gi|4502181 aquaporin 4 isoform a [Homo sapiens]
Length = 323
Score = 216 bits (550), Expect = 2e-56
Identities = 109/224 (48%), Positives = 148/224 (66%), Gaps = 3/224 (1%)
Query: 10 FWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGH 69
FW+AV AEFLA +FV +S+GS + + G + D V +SL FGLSIAT+ Q GH
Sbjct: 34 FWKAVTAEFLAMLIFVLLSLGSTINWG---GTEKPLPVDMVLISLCFGLSIATMVQCFGH 90
Query: 70 ISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDL 129
ISG H+NPAVT+ ++ + +ISI +++ YI AQC+GAI+ IL +T LG +
Sbjct: 91 ISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMV 150
Query: 130 ADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGC 189
+ +G GL +E+I T QLV + A+ D +R D+ GS LAIG SVA+GHL AI+YTG
Sbjct: 151 HGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGA 210
Query: 190 GINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAP 233
+NPARSFG AVI N+ NHWI+WVGP IG LA +Y+++ P
Sbjct: 211 SMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCP 254
>gi|86792455 aquaporin 6 [Homo sapiens]
Length = 282
Score = 202 bits (515), Expect = 2e-52
Identities = 112/244 (45%), Positives = 154/244 (63%), Gaps = 10/244 (4%)
Query: 8 KLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSV 67
K RA+ AEFLAT L+VF +GS + ++P TA+ +++++ F L A Q
Sbjct: 21 KAISRALFAEFLATGLYVFFGVGSVM--RWP-----TALPSVLQIAITFNLVTAMAVQVT 73
Query: 68 GHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRN 127
SGAH NPAVTL L+ IS+ RA+ Y+ AQ VGA V A+L G+ +LG N
Sbjct: 74 WKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGIN 133
Query: 128 DLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYT 187
+ + V++GQ + +E++ TLQLVLCV A+TD R+ GS IG+SVALGHL+ I +T
Sbjct: 134 VVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTS--GSPATMIGISVALGHLIGIHFT 191
Query: 188 GCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTS 247
GC +NPARSFG A+I F+ HW+FWVGP +G LA LIY+F+L P + L R+ + T
Sbjct: 192 GCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTKTLAQRLAILT- 250
Query: 248 GQVE 251
G VE
Sbjct: 251 GTVE 254
>gi|45446752 aquaporin 8 [Homo sapiens]
Length = 261
Score = 99.0 bits (245), Expect = 4e-21
Identities = 70/222 (31%), Positives = 113/222 (50%), Gaps = 16/222 (7%)
Query: 10 FWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGH 69
F + + E L + LF+FI S + G + +Q + LA GL IATL G+
Sbjct: 34 FVQPCLVELLGSALFIFIGCLSVI----ENGTDTGLLQPALAHGLALGLVIATL----GN 85
Query: 70 ISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDL 129
ISG H NPAV+L +L +++ L Y ++Q +G ++ A+ ++ +
Sbjct: 86 ISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAF 145
Query: 130 ADGVNSGQGLGI---EIIGT--LQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAI 184
GQ G EII T L L +C+ A ++ + G AP +IG +V + L
Sbjct: 146 VTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTK---GPLAPFSIGFAVTVDILAGG 202
Query: 185 DYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLI 226
+G +NPAR+FG AV+ ++++ HWI+W+GP + G L L+
Sbjct: 203 PVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLLVGLL 244
>gi|4826645 aquaporin 3 [Homo sapiens]
Length = 292
Score = 77.4 bits (189), Expect = 1e-14
Identities = 69/266 (25%), Positives = 107/266 (40%), Gaps = 38/266 (14%)
Query: 12 RAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHIS 71
R +AE L T + V GS G + + ++LAFG ++ G +S
Sbjct: 23 RQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLT----INLAFGFAVTLGILIAGQVS 78
Query: 72 GAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLAD 131
GAHLNPAVT + + + +Y +AQ +GA + I+ G+ +
Sbjct: 79 GAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLFVS 138
Query: 132 GVNSGQGLGI---------------EIIGTLQLVLCVLATTDRRRRDL-GGSAPLAIGLS 175
G N G+ + IGT L++CVLA D + G +GL
Sbjct: 139 GPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLV 198
Query: 176 V-ALGHLLAIDYTGCGINPARSF-----------GSAVITHNFSNHWIFWVGPFIGGALA 223
V +G + + +G +NPAR F GSAV T W+ V P +G
Sbjct: 199 VLVIGTSMGFN-SGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGSIAG 257
Query: 224 VLIYDFILA-----PRSSDLTDRVKV 244
V +Y ++ P S+ + VK+
Sbjct: 258 VFVYQLMIGCHLEQPPPSNEEENVKL 283
>gi|157266307 aquaporin 9 [Homo sapiens]
Length = 295
Score = 76.6 bits (187), Expect = 2e-14
Identities = 74/264 (28%), Positives = 118/264 (44%), Gaps = 46/264 (17%)
Query: 5 FKKKLFWRAVVA-----EFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLS 59
FK++L ++ +A EFL T + + + G G + NV S+A ++
Sbjct: 12 FKQRLVLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMA 71
Query: 60 IATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGI---- 115
I G +SG H+NPAV+L + L ++ F+ Y+ AQ +GA V A + GI
Sbjct: 72 IYV----AGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDG 127
Query: 116 TSSLTGNSL---GRNDL--------ADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDL 164
S G L G N A ++ +++ T+ L++ V A D R+L
Sbjct: 128 LMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFD--SRNL 185
Query: 165 G---GSAPLAIG-LSVALGHLLAIDYTGCGINPARSFGSAVIT-------------HNFS 207
G G P+AIG L + + L ++ +GC +NPAR + T +NF
Sbjct: 186 GAPRGLEPIAIGLLIIVIASSLGLN-SGCAMNPARDLSPRLFTALAGWGFEVFRAGNNF- 243
Query: 208 NHWIFWVGPFIGGALAVLIYDFIL 231
WI VGP +G + LIY ++
Sbjct: 244 -WWIPVVGPLVGAVIGGLIYVLVI 266
>gi|22538420 aquaporin 10 [Homo sapiens]
Length = 301
Score = 65.1 bits (157), Expect = 6e-11
Identities = 67/290 (23%), Positives = 124/290 (42%), Gaps = 35/290 (12%)
Query: 7 KKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQS 66
+ L R +AEFL + + ++ G+ V + +T + + LA L++
Sbjct: 17 RSLLARQCLAEFLGVFVLMLLTQGAVA---QAVTSGETK-GNFFTMFLAGSLAVTIAIYV 72
Query: 67 VGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGR 126
G++SGAHLNPA +L + + ++ + +YI+ Q + A A+ + N G
Sbjct: 73 GGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGG 132
Query: 127 NDLADG---------------VNSGQGLGIEIIGTLQLVLCVLATTDRRRRDL-GGSAPL 170
N G ++ G +++GT L++ +LA DRR + + G P+
Sbjct: 133 NLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPV 192
Query: 171 AIG-LSVALGHLLAIDYTGCGINPARSFGSAVITH---------NFSNHWIFW---VGPF 217
+G L +ALG + + G +NPAR G + T+ + N W +W V P
Sbjct: 193 VVGMLILALGLSMGAN-CGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGW-WWVPVVAPL 250
Query: 218 IGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMK 267
+G + Y ++A + + + S Q + +L+ +E K
Sbjct: 251 VGATVGTATYQLLVALHHPEGPEPAQDLVSAQHKASELETPASAQMLECK 300
>gi|4502187 aquaporin 7 [Homo sapiens]
Length = 342
Score = 64.7 bits (156), Expect = 8e-11
Identities = 70/252 (27%), Positives = 112/252 (44%), Gaps = 34/252 (13%)
Query: 4 EFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATL 63
E ++ R +AEF++T + + +GS + V N + + V+L FG +
Sbjct: 27 EILQRKMVREFLAEFMSTYVMMVFGLGSVA---HMVLNKKYG--SYLGVNLGFGFGVTMG 81
Query: 64 AQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVA---------TAIL-- 112
G ISGAH+N AVT ++ + +Y++ Q +G+ +A TAIL
Sbjct: 82 VHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHF 141
Query: 113 SG----ITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRD-LGGS 167
SG +T + + L D + +G E T L LC+ A TD+ L G+
Sbjct: 142 SGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGT 201
Query: 168 APLAIG-LSVALGHLLAIDYTGCGINPAR-----------SFGSAVITHNFSNHWIFWVG 215
L IG L V +G L ++ TG INP+R +G V ++ + W+ V
Sbjct: 202 EALVIGILVVIIGVSLGMN-TGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVA 260
Query: 216 PFIGGALAVLIY 227
P +G L +IY
Sbjct: 261 PLLGAYLGGIIY 272
>gi|40538880 aquaporin 12A [Homo sapiens]
Length = 295
Score = 35.0 bits (79), Expect = 0.069
Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 16/169 (9%)
Query: 70 ISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITS-SLTGNSLGRND 128
+ GA NP V+L L + S+ L+ + AQ +G A ++ + L+ L ++
Sbjct: 75 LDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCWAWELSDLHLLQSL 134
Query: 129 LADGVNSGQGLGIEIIGTLQLVLCV----LATTDRRRRDLGGSAPLAIGLSVALGHLLAI 184
+A +S + G L C L R S P A+ L V + A
Sbjct: 135 MAQSCSSALRTSVPH-GALVEAACAFCFHLTLLHLRHSPPAYSGP-AVALLVTVTAYTAG 192
Query: 185 DYTGCGINPARSFGSAVITHNFSNHW------IFWVGPFIGGALAVLIY 227
+T NPA + A +T S H ++W+GP G LAVL++
Sbjct: 193 PFTSAFFNPALA---ASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLH 238
>gi|156447037 aquaporin 12B [Homo sapiens]
Length = 307
Score = 33.9 bits (76), Expect = 0.15
Identities = 44/169 (26%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 70 ISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITS-SLTGNSLGRND 128
+ GA NP V+L L + S+ L+ + AQ +G A + + L+ L ++
Sbjct: 87 LDGASANPTVSLQEFLMAEESLPGTLLKLAAQGLGMQAACTLTRLCWAWELSDLHLLQSL 146
Query: 129 LADGVNSGQGLGIEIIGTLQLVLCV----LATTDRRRRDLGGSAPLAIGLSVALGHLLAI 184
+A +S + G L C L R S P A+ L V + A
Sbjct: 147 MAQSCSSALRTSVPH-GALVEAACAFCFHLTLLHLRHSPPAYSGP-AVALLVTVTAYTAG 204
Query: 185 DYTGCGINPARSFGSAVITHNFSNHW------IFWVGPFIGGALAVLIY 227
+T NPA + A +T S H ++W+GP G LAVL++
Sbjct: 205 PFTSAFFNPALA---ASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLH 250
>gi|194272186 enhancer of polycomb homolog 2 [Homo sapiens]
Length = 807
Score = 33.1 bits (74), Expect = 0.26
Identities = 16/46 (34%), Positives = 26/46 (56%)
Query: 34 GFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAV 79
G P G ++T N+ +S + G+S L ++VGH + HL PA+
Sbjct: 667 GVVQPSGTSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPAL 712
>gi|156151386 hypothetical protein LOC80157 [Homo sapiens]
Length = 699
Score = 31.6 bits (70), Expect = 0.76
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 8/66 (12%)
Query: 10 FWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGH 69
FW+ V +++ T L + I+IGS F+ P + V LA G+S + + Q+V
Sbjct: 60 FWKLVNKKWMLTLLRI-ITIGSIASFQAPNAKLRLMV-------LALGVSSSLIVQAVTW 111
Query: 70 ISGAHL 75
SG+HL
Sbjct: 112 WSGSHL 117
>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
Length = 426
Score = 29.6 bits (65), Expect = 2.9
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
Query: 21 TTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAV- 79
T I+ G + + + V + Q D + AF LS+ ++ VG + L AV
Sbjct: 220 TVALTLINTGYFIPYLHLVAHLQDLDWDPLPA--AFLLSVVAISDLVGRVVSGWLGDAVP 277
Query: 80 ---TLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITS 117
T L+L ++ ++ +AQ A+VA A+ G TS
Sbjct: 278 GPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTS 318
>gi|16306483 solute carrier family 26, member 7 isoform a [Homo
sapiens]
Length = 656
Score = 29.6 bits (65), Expect = 2.9
Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 11/114 (9%)
Query: 13 AVVAEFLATTLFVFISI-----GSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSV 67
AV+ E L +++ GSA FKY + +NQ + + ++ A ++
Sbjct: 307 AVITEAFGVALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAM 366
Query: 68 GHISGAHLNPAVT-LGLLLSC-----QISIFRALMYIIAQCVGAIVATAILSGI 115
G +G + A T + L+SC I L+Y + CV A + L G+
Sbjct: 367 GRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGM 420
>gi|20336282 solute carrier family 26, member 7 isoform b [Homo
sapiens]
Length = 663
Score = 29.6 bits (65), Expect = 2.9
Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 11/114 (9%)
Query: 13 AVVAEFLATTLFVFISI-----GSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSV 67
AV+ E L +++ GSA FKY + +NQ + + ++ A ++
Sbjct: 307 AVITEAFGVALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAM 366
Query: 68 GHISGAHLNPAVT-LGLLLSC-----QISIFRALMYIIAQCVGAIVATAILSGI 115
G +G + A T + L+SC I L+Y + CV A + L G+
Sbjct: 367 GRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGM 420
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3
[Homo sapiens]
Length = 840
Score = 28.9 bits (63), Expect = 4.9
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 11/74 (14%)
Query: 146 TLQLVLC-VLATTDRRRRDLGGSAPLAI----GLSVALGHLLAIDYTGC------GINPA 194
T Q LC V TTD R+ GG+ LAI GL + LG + I YT G + +
Sbjct: 752 TSQPPLCKVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGS 811
Query: 195 RSFGSAVITHNFSN 208
S+ + +FSN
Sbjct: 812 HSYSPITVESDFSN 825
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2
[Homo sapiens]
Length = 910
Score = 28.9 bits (63), Expect = 4.9
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 11/74 (14%)
Query: 146 TLQLVLC-VLATTDRRRRDLGGSAPLAI----GLSVALGHLLAIDYTGC------GINPA 194
T Q LC V TTD R+ GG+ LAI GL + LG + I YT G + +
Sbjct: 822 TSQPPLCKVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGKSLFGFSGS 881
Query: 195 RSFGSAVITHNFSN 208
S+ + +FSN
Sbjct: 882 HSYSPITVESDFSN 895
>gi|154937330 sodium-dependent glucose transporter 1 [Homo sapiens]
Length = 518
Score = 28.1 bits (61), Expect = 8.4
Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 7/109 (6%)
Query: 26 FISIGSALGFKYPVGNN-QTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLL 84
F+ +G ++ P + T V N+ SL+F L G + G L + LL
Sbjct: 6 FLGLGLSVAIVGPTFQDLATNVNRNIS-SLSFIFVGRALGYLSGSVIGGFLVDVMNYFLL 64
Query: 85 LSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGV 133
L +S +Y++ C TAIL + S+ G S+G D V
Sbjct: 65 LGISMSATTVGLYLVPFC-----KTAILLTVMMSIFGVSIGILDTGGNV 108
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,660,508
Number of Sequences: 37866
Number of extensions: 335748
Number of successful extensions: 654
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 617
Number of HSP's gapped (non-prelim): 22
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.