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Search of human proteins with 37693519
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37693519 BMP-binding endothelial regulator precursor protein
[Homo sapiens]
(685 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37693519 BMP-binding endothelial regulator precursor protein ... 1513 0.0
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 394 e-109
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 189 7e-48
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 189 7e-48
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 187 2e-47
gi|134031945 SCO-spondin [Homo sapiens] 186 5e-47
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 185 1e-46
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 185 1e-46
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 182 1e-45
gi|134268640 tectorin alpha precursor [Homo sapiens] 180 3e-45
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 172 9e-43
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 166 9e-41
gi|116284392 mucin 2 precursor [Homo sapiens] 162 1e-39
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 162 1e-39
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 159 6e-39
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 159 6e-39
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 159 6e-39
gi|161019170 mucin 5AC [Homo sapiens] 157 3e-38
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 157 3e-38
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 155 1e-37
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 155 1e-37
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 154 2e-37
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 145 9e-35
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 145 9e-35
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 145 9e-35
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 145 9e-35
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 145 9e-35
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 145 9e-35
gi|108773804 Fraser syndrome 1 [Homo sapiens] 138 1e-32
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 135 1e-31
>gi|37693519 BMP-binding endothelial regulator precursor protein
[Homo sapiens]
Length = 685
Score = 1513 bits (3916), Expect = 0.0
Identities = 685/685 (100%), Positives = 685/685 (100%)
Query: 1 MLWFSGVGALAERYCRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIP 60
MLWFSGVGALAERYCRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIP
Sbjct: 1 MLWFSGVGALAERYCRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIP 60
Query: 61 FITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFK 120
FITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFK
Sbjct: 61 FITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFK 120
Query: 121 WQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQ 180
WQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQ
Sbjct: 121 WQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQ 180
Query: 181 PEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLF 240
PEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLF
Sbjct: 181 PEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLF 240
Query: 241 RSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKV 300
RSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKV
Sbjct: 241 RSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKV 300
Query: 301 CKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEK 360
CKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEK
Sbjct: 301 CKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEK 360
Query: 361 PGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKS 420
PGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKS
Sbjct: 361 PGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKS 420
Query: 421 VELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSF 480
VELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSF
Sbjct: 421 VELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSF 480
Query: 481 VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRK 540
VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRK
Sbjct: 481 VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRK 540
Query: 541 PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCE 600
PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCE
Sbjct: 541 PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCE 600
Query: 601 SFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCV 660
SFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCV
Sbjct: 601 SFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCV 660
Query: 661 AGCHCPANLVLHKGRCIKPVLCPQR 685
AGCHCPANLVLHKGRCIKPVLCPQR
Sbjct: 661 AGCHCPANLVLHKGRCIKPVLCPQR 685
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 394 bits (1013), Expect = e-109
Identities = 223/651 (34%), Positives = 310/651 (47%), Gaps = 60/651 (9%)
Query: 67 CIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAE 126
C C C +V+C R +CP L C L + +RG+CC +C+GC G + +W P
Sbjct: 857 CEWCRCQAGQVSCVRLQCPPLP--CKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDS 914
Query: 127 PCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKC 186
C C EGVVT + ++C+ C P + CCP C C EG +Y+ GE FQP C
Sbjct: 915 ACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPC 974
Query: 187 TKCSCT-----GGRTQCVREVCP-ILSCPQHLSHIPPG--QCCPKCLGQRKVFDLPFGSC 238
C C +C R CP ++ CP +PPG CCP C
Sbjct: 975 EVCICEPQPEGPPSLRCHRRQCPSLVGCPPS-QLLPPGPQHCCPTC-------------- 1019
Query: 239 LFRSDVYDNGSSFLY-------DNCTACTCRDSTVVCKRKCSHPGGCDQGQE-----GCC 286
++ N S L D C C C+D T +C + C + CC
Sbjct: 1020 ---AEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
Query: 287 EECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCP-QG 345
C R P + C + GE W+ CT C+C+ G C++++C P+S P +
Sbjct: 1077 PVC--RAPTQS---CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKA 1131
Query: 346 KILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLV 405
L+ CCP C +P C FGDPHY TFDGR +FQG+C YVL KDC S F V V
Sbjct: 1132 PALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHS--GDFSVHV 1189
Query: 406 KNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALP-CRAPHFHIDLDGYLLK 464
ND R +WT+ V ++LG+ V L Q V +G +ALP + P +++L G+ +
Sbjct: 1190 TNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVI 1249
Query: 465 VTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAE 524
+ + GL++ WDG S VEV +G+ CGLCGN+NG +DDL G +G F
Sbjct: 1250 LHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGN 1309
Query: 525 SWRVESNEFCNRP--QRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYR 582
SW+V + RP + V + + A+ C LKS F CH+ V F+
Sbjct: 1310 SWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFA 1369
Query: 583 SCVTDMCECPVHKN---CYCESFLAYTRACQREGIKVHWEPQQNC-AATQCKHGAVYDTC 638
+CV D+C C + C C++ AY C++ G+ W C + G V+D C
Sbjct: 1370 ACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDEC 1429
Query: 639 GPGCIKTCDNWN-EIGP----CNKPCVAGCHCPANLVLHKGRCIKPVLCPQ 684
GP C +TC N + +G C +PCV GC CPA LV H+ CI P CPQ
Sbjct: 1430 GPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
Score = 154 bits (388), Expect = 3e-37
Identities = 122/406 (30%), Positives = 163/406 (40%), Gaps = 100/406 (24%)
Query: 16 RRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNK 75
R PG TCC + C G FL G + GE P + +PC C C N
Sbjct: 239 RPLPG-TCCPV----CDGC-------FLNG---REHRSGE----PVGSGDPCSHCRCANG 279
Query: 76 EVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNS--SFKWQSPAEPCVLRQC 133
V C+ CP + C K G CC C GC Y+G+ Y S +F+ Q CV C
Sbjct: 280 SVQCEPLPCPPVP--CRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGL-CVRCSC 336
Query: 134 QEGVVTESGVRC-VVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCT 192
Q G V+ C V C P +C P C +G ++ EG +++P+G CT C C
Sbjct: 337 QAGEVSCEEQECPVTPCALPASGRQLC----PACELDGEEFAEGVQWEPDGRPCTACVCQ 392
Query: 193 GGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFL 252
G +C +CP C QH + PPG CCP C SC + S VY NG +F
Sbjct: 393 DGVPKCGAVLCPPAPC-QHPTQ-PPGACCPSC-----------DSCTYHSQVYANGQNFT 439
Query: 253 YDN--CTACTCRDSTVVCKRKCSHPGGCDQGQEG---C---CEECLL------------- 291
+ C AC C+D TV C P C + Q G C C +C+L
Sbjct: 440 DADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSH 499
Query: 292 -----------------------RVP----------PEDIKVCKFGNKIFQDGEMW--SS 316
R P P D C FG K + G + S
Sbjct: 500 PRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPS 559
Query: 317 INCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPG 362
C +C C+ G +C ++C+P+ CP+ +L + CCP C G
Sbjct: 560 DPCRLCRCLSGNVQCLARRCVPL-PCPEPVLLPGE-CCPQCPAPAG 603
Score = 153 bits (387), Expect = 4e-37
Identities = 96/319 (30%), Positives = 136/319 (42%), Gaps = 48/319 (15%)
Query: 66 PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125
PC +C CL VTC R C C+ + G CC C+GC Y G T S P
Sbjct: 738 PCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPL 795
Query: 126 EP-CVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMC-CPTCPGCVFEGVQYQEGEEFQPE 182
+P C L CQEG + C C +P G C CP C C+ +G ++Q+GEEF+
Sbjct: 796 DPTCSLCTCQEGSMRCQKKPCPPALCPHPSP--GPCFCPVCHSCLSQGREHQDGEEFEGP 853
Query: 183 GSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRS 242
C C C G+ CVR CP L C ++ G CCP+C G CL
Sbjct: 854 AGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTE--RGSCCPRCRG-----------CLAHG 900
Query: 243 DVYDNGSSFLYDN--CTACTCRDSTVVCKR-----KCSHPGGCDQGQEGCCEECLLRVPP 295
+ + GS ++ + C++C C + V C R C+ P QG CC +C
Sbjct: 901 EEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQP---RQGPHDCCPQC------ 951
Query: 296 EDIKVCKFGNKIFQDGEMW--SSINCTICACV-----KGRTECRNKQCIPISSCPQGKIL 348
C+ + ++ GE + + C +C C C +QC + CP ++L
Sbjct: 952 ---SDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLL 1008
Query: 349 --NRKGCCPICTEKPGVCT 365
+ CCP C E C+
Sbjct: 1009 PPGPQHCCPTCAEALSNCS 1027
Score = 136 bits (342), Expect = 7e-32
Identities = 106/372 (28%), Positives = 129/372 (34%), Gaps = 85/372 (22%)
Query: 50 CENEGEVLQ--IPFITDN-PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK 106
CE +GE + + D PC CVC + C CP C + GACC C
Sbjct: 366 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCP--PAPCQHPTQPPGACCPSCD 423
Query: 107 GCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPTCPG 165
CTY Y + + PC CQ+G VT S V C C P G CCP CP
Sbjct: 424 SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPD 483
Query: 166 CVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPK-C 224
C+ E + +GE F C +C C G C CP C +H PG CCP C
Sbjct: 484 CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC----AHPLPGTCCPNDC 539
Query: 225 LGQRKVFDLPFGSCLFRSDVYDNGSSFLY--DNCTACTCRDSTVVCKRK----------- 271
G C F Y +G+ F + D C C C V C +
Sbjct: 540 SG-----------CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 588
Query: 272 ---------CSHPGGCD-------QGQE------GCCEECL----------LRVPP---- 295
C P GC + QE C CL L PP
Sbjct: 589 LLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCA 648
Query: 296 --------EDIKVCKFGNKIFQDGEMWSS--INCTICACVKGRTECRNKQCIPISSCPQG 345
C + K F GE + S C +C C +G C K C P + CP
Sbjct: 649 HPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP-ALCP-- 705
Query: 346 KILNRKGCCPIC 357
R CCP C
Sbjct: 706 -FPARGDCCPDC 716
Score = 128 bits (322), Expect = 2e-29
Identities = 87/298 (29%), Positives = 117/298 (39%), Gaps = 38/298 (12%)
Query: 67 CIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAE 126
C C CL V C+ C L+ C + G CC C CT G+ + +W +P +
Sbjct: 156 CTTCRCLTGAVQCQGPSCSELN--CLESCTPPGECCPIC--CTEGGSHWEHGQEWTTPGD 211
Query: 127 PCVLRQCQEGVVTESGVRCVVHCKNPLEHL-GMCCPTCPGCVFEGVQYQEGEEFQPEGSK 185
PC + +C EG + C C P L G CCP C GC G +++ GE G
Sbjct: 212 PCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV-GSGDP 270
Query: 186 CTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVY 245
C+ C C G QC CP + C +H I PGQCCP C G C ++ Y
Sbjct: 271 CSHCRCANGSVQCEPLPCPPVPC-RHPGKI-PGQCCPVCDG-----------CEYQGHQY 317
Query: 246 DNGSSFLYDN---CTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDI-KVC 301
+ +F C C+C+ V C+ QE C L + C
Sbjct: 318 QSQETFRLQERGLCVRCSCQAGEVSCEE-----------QECPVTPCALPASGRQLCPAC 366
Query: 302 KFGNKIFQDGEMWSSIN--CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
+ + F +G W CT C C G +C C P + C Q CCP C
Sbjct: 367 ELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLC-PPAPC-QHPTQPPGACCPSC 422
Score = 126 bits (316), Expect = 8e-29
Identities = 94/339 (27%), Positives = 134/339 (39%), Gaps = 54/339 (15%)
Query: 65 NPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK---GCTYEGNTYNSSFKW 121
+PC +C CL+ V C +C L C + G CC QC GC G + ++
Sbjct: 560 DPCRLCRCLSGNVQCLARRCVPLP--CPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEY 617
Query: 122 QSP-AEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEF 179
SP +PC C +G V+ + C C +P + G CCP+C GC+++G ++ GE F
Sbjct: 618 FSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ--GPCCPSCDGCLYQGKEFASGERF 675
Query: 180 QPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCL 239
+ C C C G C + C CP G CCP C G C
Sbjct: 676 PSPTAACHLCLCWEGSVSCEPKACAPALCP----FPARGDCCPDCDG-----------CE 720
Query: 240 FRSDVYDNGSSF--LYDNCTACTCRDSTVVCKRKCSHPGGCDQ---GQEGCCEECLLRVP 294
+ + Y + F + C CTC V C R+ P GC CC C
Sbjct: 721 YLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTC----- 775
Query: 295 PEDIKVCKFGNKIFQDGEMWS---SINCTICACVKGRTECRNKQCIPISSCPQGKILNRK 351
+ C++ GE C++C C +G C+ K C P + CP +
Sbjct: 776 ----QGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPC-PPALCPHP---SPG 827
Query: 352 GC-CPICTEKPGVCTVFGDPHYNTFDGRTFNF-QGTCQY 388
C CP+C C G H DG F G+C++
Sbjct: 828 PCFCPVCHS----CLSQGREHQ---DGEEFEGPAGSCEW 859
Score = 96.7 bits (239), Expect = 6e-20
Identities = 78/285 (27%), Positives = 109/285 (38%), Gaps = 50/285 (17%)
Query: 91 CALAIKQRGA--CCEQ-----CKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGV 143
C + Q GA C Q C+GC+ G TY + + A C +C G V G
Sbjct: 114 CTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDA--CTTCRCLTGAVQCQGP 171
Query: 144 RC-VVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREV 202
C ++C G CCP C C G ++ G+E+ G C C C G QC +
Sbjct: 172 SCSELNCLESCTPPGECCPIC--CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
Query: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSF-LYDNCTACTC 261
C L CP + PG CCP C G C + +G D C+ C C
Sbjct: 230 CASL-CPYPARPL-PGTCCPVCDG-----------CFLNGREHRSGEPVGSGDPCSHCRC 276
Query: 262 RDSTVVCKR------KCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWS 315
+ +V C+ C HPG GQ CC C C++ +Q E +
Sbjct: 277 ANGSVQCEPLPCPPVPCRHPGKI-PGQ--CCPVC---------DGCEYQGHQYQSQETFR 324
Query: 316 SIN---CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
C C+C G C ++C P++ C + + CP C
Sbjct: 325 LQERGLCVRCSCQAGEVSCEEQEC-PVTPC--ALPASGRQLCPAC 366
Score = 80.5 bits (197), Expect = 5e-15
Identities = 62/242 (25%), Positives = 90/242 (37%), Gaps = 54/242 (22%)
Query: 120 KWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEF 179
+W E V+ ++ ++ VR + C+ C P P C G + EG +
Sbjct: 58 EWLGRLEAAVMELREQNKDLQTRVRQLESCE--------CHPASPQCWGLGRAWPEGARW 109
Query: 180 QPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCL 239
+P+ CT C C G C + HL H C G C
Sbjct: 110 EPDA--CTACVCQDGAAHCGPQA--------HLPH---------CRG-----------CS 139
Query: 240 FRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDI- 298
Y NG +F D CT C C V C+ G + C E C PP +
Sbjct: 140 QNGQTYGNGETFSPDACTTCRCLTGAVQCQ-------GPSCSELNCLESC---TPPGECC 189
Query: 299 -KVCKFGNKIFQDGEMWSSIN--CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCP 355
C G ++ G+ W++ C IC C++G +CR ++C S CP CCP
Sbjct: 190 PICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQREC--ASLCPYPARPLPGTCCP 247
Query: 356 IC 357
+C
Sbjct: 248 VC 249
Score = 50.4 bits (119), Expect = 5e-06
Identities = 35/124 (28%), Positives = 50/124 (40%), Gaps = 35/124 (28%)
Query: 245 YDNGSSFLYDNCTACTCRDSTVVC--KRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCK 302
+ G+ + D CTAC C+D C + H GC Q +
Sbjct: 103 WPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQ------------------T 144
Query: 303 FGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPIS---SC-PQGKILNRKGCCPICT 358
+GN GE +S CT C C+ G +C+ C ++ SC P G+ CCPIC
Sbjct: 145 YGN-----GETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGE------CCPICC 193
Query: 359 EKPG 362
+ G
Sbjct: 194 TEGG 197
Score = 31.2 bits (69), Expect = 3.3
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 50 CENEG-EVLQIPFITDNPCIMCVCLNKEVTCKREKCPVLS--RDCALAIKQRGACCEQC 105
C ++G EV T + C C C+ V C+ ++C LS D A A+ G+CC +C
Sbjct: 1086 CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSP-GSCCPRC 1143
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 189 bits (480), Expect = 7e-48
Identities = 137/453 (30%), Positives = 192/453 (42%), Gaps = 33/453 (7%)
Query: 257 TACTCRDSTVVCK-----RKCSHPGGCDQGQ--------EGC-CEECLLRVPPEDIKV-- 300
T T R ST C C+ P C + EGC C L I+
Sbjct: 1033 TTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASS 1092
Query: 301 --CKFGNKIFQDGEMWSSINCTI-CACVKG-RTECRNKQCIPISSCPQGKILNRKGCCPI 356
C + N ++ G W S NCT C C G R EC+ QC + C + GC P
Sbjct: 1093 CNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKN--GQYGCHPY 1150
Query: 357 CTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPF-QVLVKNDARRTRSF 415
C V+GDPHY TFDGR F F G C Y+L + C + PF +V KN+ +
Sbjct: 1151 AGT--ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV 1208
Query: 416 SWTKSVELVLGESRVSLQQHLTVRWNGSRIALPC-RAPHFHIDLDGYLLKVTTKAGLEIS 474
S V + L ES V+L + G ++ LP + + G +++ T+ GL +
Sbjct: 1209 SCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 475 WDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNE-- 532
WDGD + V + GKLCGLCGNY+G+ +D + DG+ D ++ SW+ + +E
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 533 FCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCE 590
C + Q P C +++ + C +L F+TC V A+F+ SC+ DMC
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 591 CPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNW 649
++ C T CQ G V W C C + Y C C TC +
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMA-CPPNSKYSLCAKPCPDTCHSG 1446
Query: 650 NEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLC 682
C+ CV C C VL CI C
Sbjct: 1447 FSGMFCSDRCVEACECNPGFVLSGLECIPRSQC 1479
Score = 163 bits (412), Expect = 6e-40
Identities = 132/449 (29%), Positives = 177/449 (39%), Gaps = 40/449 (8%)
Query: 258 ACTCRDSTVVCKRKCSHPGGCDQGQEG------CCEEC----------LLRVPPEDIKVC 301
AC +C + C P C G G C E C L +P
Sbjct: 1425 ACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCL 1482
Query: 302 KFGNKIFQDGEMWSSINCT-ICACVKG-RTECRNKQCIPISSCPQGKILNRKGCCPICTE 359
F+ GE W C +C C R C+ +C C Q + G +
Sbjct: 1483 HPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQ-----QDGIYGCHAQ 1537
Query: 360 KPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPA--SPFQVLVKNDARR-TRSFS 416
CT GDPHY TFDG +F GTC YVLT+ C S + S F V N+ R S
Sbjct: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVS 1597
Query: 417 WTKSVELVLGESRVSLQQHLTVRWNGSRIALPC--RAPHFHIDLDGYLLKVTTKAGLEIS 474
+ K+V + + + +SL + V NG R+ALP I L L+ + T GL++
Sbjct: 1598 YIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
Query: 475 WDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV-ESNE- 532
+DG VEV G+LCGLCGNYN + DD + D D +W++ ES+E
Sbjct: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
Query: 533 FCNRPQRKPVPELCQGTVKVKLRAHRECQKL--KSWEFQTCHSTVDYATFYRSCVTDMCE 590
C K P CQ + ++ C L F CH V + + SCV C
Sbjct: 1718 GCFLVGGK--PSSCQEN-SMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
Query: 591 CPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWN 650
C S AY C + G W + C +C G+ Y C C TC + N
Sbjct: 1775 TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFC-PMRCPPGSSYSPCSSPCPDTCSSIN 1833
Query: 651 EIGPCNK--PCVAGCHCPANLVLHKGRCI 677
C K PC C C +L C+
Sbjct: 1834 NPRDCPKALPCAESCECQKGHILSGTSCV 1862
Score = 126 bits (316), Expect = 8e-29
Identities = 123/511 (24%), Positives = 192/511 (37%), Gaps = 76/511 (14%)
Query: 200 REVCPILSCPQHLSHIPPGQCCPK-CLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTA 258
R CP + CP S+ P CP C D P S
Sbjct: 1805 RTFCP-MRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAES---------------- 1847
Query: 259 CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSIN 318
C C+ ++ C G C GC + P GE W + N
Sbjct: 1848 CECQKGHILSGTSCVPLGQC-----GCTDPAGSYHPV---------------GERWYTEN 1887
Query: 319 -CT-ICAC-VKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTF 375
CT +C C V C C P C L R + GVC + G+ HY +F
Sbjct: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGV-----GVCQLPGESHYVSF 1942
Query: 376 DGRTFNFQGTCQYVLTKDCS-SPASPF-QVLVKNDARR--TRSFSWTKSVELVLGESRVS 431
DG + C VL K C + A PF ++ K++ T +F V + + +++V+
Sbjct: 1943 DGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFR-LHEVYIDIYDAQVT 2001
Query: 432 LQQHLTVRWNGSRIALPC--RAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHL 489
LQ+ V N ++ LP + P + V K G+++ +DG+ +E+
Sbjct: 2002 LQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
Query: 490 KGKLCGLCGNYNGHKRDDLI-------GGDGNF-----KFDVDDFAESWRVESNEFCNRP 537
GK+CG+CGN+N + D+L+ D F D+D +S V+ +
Sbjct: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQ 2121
Query: 538 QRKPVPELCQGTVKVKLRAHRECQ-KLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKN 596
Q P ++ RA +C+ L++ + C S +D F C +CE
Sbjct: 2122 QENPSGNCRAADLR---RAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
Query: 597 CYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCN 656
C++ A+ CQ +G+K + +C + Y C P C +C W+ G C
Sbjct: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSC--WDLDGRCE 2236
Query: 657 -----KPCVAGCHCPANLVLHKGRCIKPVLC 682
C GC C VL + +C+ C
Sbjct: 2237 GAKVPSACAEGCICQPGYVLSEDKCVPRSQC 2267
Score = 113 bits (282), Expect = 7e-25
Identities = 106/410 (25%), Positives = 163/410 (39%), Gaps = 61/410 (14%)
Query: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR 262
CP L CP + S+ C P C +DL G C G+ C C+
Sbjct: 2207 CP-LECPAYSSYT---NCLPSC--SPSCWDLD-GRC--------EGAKVPSACAEGCICQ 2251
Query: 263 DSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI- 321
V+ + KC C GC + +P G+ W S CT
Sbjct: 2252 PGYVLSEDKCVPRSQC-----GCKDAHGGSIPL---------------GKSWVSSGCTEK 2291
Query: 322 CACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFN 381
C C G +C + +C S C + C ++K C+V+GDP Y TFDG ++
Sbjct: 2292 CVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCV---SDKSEQCSVYGDPRYLTFDGFSYR 2348
Query: 382 FQGTCQYVLTKDCS---SPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTV 438
QG YVL K P V +N RS + + V + +V LQ L +
Sbjct: 2349 LQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLEL 2408
Query: 439 RWNGSRIALPCRA-PHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLC 497
N ++A+P R H + L G L + T L +S+ G + +G + GLC
Sbjct: 2409 VVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLC 2468
Query: 498 GNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNR-PQRKPVPELCQGT------- 549
GNY+ ++++D++ G +++ F SW V++ + R P+ P E QG
Sbjct: 2469 GNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTG 2528
Query: 550 --------VKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMC 589
++ + + C+ L + F CH TV F CV D+C
Sbjct: 2529 LQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC 2578
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 189 bits (480), Expect = 7e-48
Identities = 137/453 (30%), Positives = 192/453 (42%), Gaps = 33/453 (7%)
Query: 257 TACTCRDSTVVCK-----RKCSHPGGCDQGQ--------EGC-CEECLLRVPPEDIKV-- 300
T T R ST C C+ P C + EGC C L I+
Sbjct: 1033 TTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASS 1092
Query: 301 --CKFGNKIFQDGEMWSSINCTI-CACVKG-RTECRNKQCIPISSCPQGKILNRKGCCPI 356
C + N ++ G W S NCT C C G R EC+ QC + C + GC P
Sbjct: 1093 CNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKN--GQYGCHPY 1150
Query: 357 CTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPF-QVLVKNDARRTRSF 415
C V+GDPHY TFDGR F F G C Y+L + C + PF +V KN+ +
Sbjct: 1151 AGT--ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV 1208
Query: 416 SWTKSVELVLGESRVSLQQHLTVRWNGSRIALPC-RAPHFHIDLDGYLLKVTTKAGLEIS 474
S V + L ES V+L + G ++ LP + + G +++ T+ GL +
Sbjct: 1209 SCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 475 WDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNE-- 532
WDGD + V + GKLCGLCGNY+G+ +D + DG+ D ++ SW+ + +E
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 533 FCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCE 590
C + Q P C +++ + C +L F+TC V A+F+ SC+ DMC
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 591 CPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNW 649
++ C T CQ G V W C C + Y C C TC +
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMA-CPPNSKYSLCAKPCPDTCHSG 1446
Query: 650 NEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLC 682
C+ CV C C VL CI C
Sbjct: 1447 FSGMFCSDRCVEACECNPGFVLSGLECIPRSQC 1479
Score = 163 bits (412), Expect = 6e-40
Identities = 132/449 (29%), Positives = 177/449 (39%), Gaps = 40/449 (8%)
Query: 258 ACTCRDSTVVCKRKCSHPGGCDQGQEG------CCEEC----------LLRVPPEDIKVC 301
AC +C + C P C G G C E C L +P
Sbjct: 1425 ACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCL 1482
Query: 302 KFGNKIFQDGEMWSSINCT-ICACVKG-RTECRNKQCIPISSCPQGKILNRKGCCPICTE 359
F+ GE W C +C C R C+ +C C Q + G +
Sbjct: 1483 HPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQ-----QDGIYGCHAQ 1537
Query: 360 KPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPA--SPFQVLVKNDARR-TRSFS 416
CT GDPHY TFDG +F GTC YVLT+ C S + S F V N+ R S
Sbjct: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVS 1597
Query: 417 WTKSVELVLGESRVSLQQHLTVRWNGSRIALPC--RAPHFHIDLDGYLLKVTTKAGLEIS 474
+ K+V + + + +SL + V NG R+ALP I L L+ + T GL++
Sbjct: 1598 YIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
Query: 475 WDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV-ESNE- 532
+DG VEV G+LCGLCGNYN + DD + D D +W++ ES+E
Sbjct: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
Query: 533 FCNRPQRKPVPELCQGTVKVKLRAHRECQKL--KSWEFQTCHSTVDYATFYRSCVTDMCE 590
C K P CQ + ++ C L F CH V + + SCV C
Sbjct: 1718 GCFLVGGK--PSSCQEN-SMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
Query: 591 CPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWN 650
C S AY C + G W + C +C G+ Y C C TC + N
Sbjct: 1775 TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFC-PMRCPPGSSYSPCSSPCPDTCSSIN 1833
Query: 651 EIGPCNK--PCVAGCHCPANLVLHKGRCI 677
C K PC C C +L C+
Sbjct: 1834 NPRDCPKALPCAESCECQKGHILSGTSCV 1862
Score = 126 bits (316), Expect = 8e-29
Identities = 123/511 (24%), Positives = 192/511 (37%), Gaps = 76/511 (14%)
Query: 200 REVCPILSCPQHLSHIPPGQCCPK-CLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTA 258
R CP + CP S+ P CP C D P S
Sbjct: 1805 RTFCP-MRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAES---------------- 1847
Query: 259 CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSIN 318
C C+ ++ C G C GC + P GE W + N
Sbjct: 1848 CECQKGHILSGTSCVPLGQC-----GCTDPAGSYHPV---------------GERWYTEN 1887
Query: 319 -CT-ICAC-VKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTF 375
CT +C C V C C P C L R + GVC + G+ HY +F
Sbjct: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGV-----GVCQLPGESHYVSF 1942
Query: 376 DGRTFNFQGTCQYVLTKDCS-SPASPF-QVLVKNDARR--TRSFSWTKSVELVLGESRVS 431
DG + C VL K C + A PF ++ K++ T +F V + + +++V+
Sbjct: 1943 DGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFR-LHEVYIDIYDAQVT 2001
Query: 432 LQQHLTVRWNGSRIALPC--RAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHL 489
LQ+ V N ++ LP + P + V K G+++ +DG+ +E+
Sbjct: 2002 LQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
Query: 490 KGKLCGLCGNYNGHKRDDLI-------GGDGNF-----KFDVDDFAESWRVESNEFCNRP 537
GK+CG+CGN+N + D+L+ D F D+D +S V+ +
Sbjct: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQ 2121
Query: 538 QRKPVPELCQGTVKVKLRAHRECQ-KLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKN 596
Q P ++ RA +C+ L++ + C S +D F C +CE
Sbjct: 2122 QENPSGNCRAADLR---RAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
Query: 597 CYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCN 656
C++ A+ CQ +G+K + +C + Y C P C +C W+ G C
Sbjct: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSC--WDLDGRCE 2236
Query: 657 -----KPCVAGCHCPANLVLHKGRCIKPVLC 682
C GC C VL + +C+ C
Sbjct: 2237 GAKVPSACAEGCICQPGYVLSEDKCVPRSQC 2267
Score = 117 bits (294), Expect = 3e-26
Identities = 117/473 (24%), Positives = 180/473 (38%), Gaps = 75/473 (15%)
Query: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR 262
CP L CP + S+ C P C +DL G C G+ C C+
Sbjct: 2207 CP-LECPAYSSYT---NCLPSC--SPSCWDLD-GRC--------EGAKVPSACAEGCICQ 2251
Query: 263 DSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI- 321
V+ + KC C GC + +P G+ W S CT
Sbjct: 2252 PGYVLSEDKCVPRSQC-----GCKDAHGGSIPL---------------GKSWVSSGCTEK 2291
Query: 322 CACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFN 381
C C G +C + +C S C + C ++K C+V+GDP Y TFDG ++
Sbjct: 2292 CVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCV---SDKSEQCSVYGDPRYLTFDGFSYR 2348
Query: 382 FQGTCQYVLTKDCS---SPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTV 438
QG YVL K P V +N RS + + V + +V LQ L +
Sbjct: 2349 LQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLEL 2408
Query: 439 RWNGSRIALPCRA-PHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLC 497
N ++A+P R H + L G L + T L +S+ G + +G + GLC
Sbjct: 2409 VVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLC 2468
Query: 498 GNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNR-PQRKPVPELCQGT------- 549
GNY+ ++++D++ G +++ F SW V++ + R P+ P E QG
Sbjct: 2469 GNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTG 2528
Query: 550 --------VKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECP---VHKN 596
++ + + C+ L + F CH TV F CV D+C +
Sbjct: 2529 LQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEE 2588
Query: 597 CYCESFLAYTRACQREGIKV-HWEPQQNCAAT----------QCKHGAVYDTC 638
C+ Y CQ G + W + C + QC+ TC
Sbjct: 2589 LRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPCQNDGQCREQGATFTC 2641
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 187 bits (476), Expect = 2e-47
Identities = 131/447 (29%), Positives = 191/447 (42%), Gaps = 41/447 (9%)
Query: 255 NCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG-EM 313
+C + + VC+ C CD G + C VP + C + G E
Sbjct: 1966 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC---VPLNNGCGCWANGTYHEAGSEF 2022
Query: 314 WSSINCTI-CACVKGRTECRNKQCIPISSCPQGKILN-----RKGCCPICTEKPGVCTVF 367
W+ C+ C C G C P +SC G++ + GC P+ T + C +
Sbjct: 2023 WADGTCSQWCRCGPGGGSL---VCTP-ASCGLGEVCGLLPSGQHGCQPVSTAE---CQAW 2075
Query: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSP---ASPFQVLVKNDARRTRSFSWTKSVELV 424
GDPHY T DG FNFQGTC+Y+L+ C P A F V V N+ R +++ S+T+SV L
Sbjct: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQ 2135
Query: 425 LGESRVSLQQHLTVRW------NGSRIALPCRAPHF-HIDLDGYLLKVTTKAGLEISWDG 477
+ ++L + RW +G + LP + H L G + VTT +GL +++DG
Sbjct: 2136 IYNHSLTL----SARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
Query: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
DSFV + G LCGLCGNYN DDL G W+V + C
Sbjct: 2192 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 2243
Query: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
KP P C + C + + + CH V A +++ C+ D C+ H
Sbjct: 2244 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHP 2303
Query: 596 NCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPC 655
C + Y ACQ G ++ + + QC + Y+ CG C +C + + C
Sbjct: 2304 GGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC 2363
Query: 656 NKPCVAGCHCPANLVLHKGRCIKPVLC 682
C GC C A VL C+ C
Sbjct: 2364 ESACREGCVCDAGFVLSGDTCVPVGQC 2390
Score = 186 bits (471), Expect = 8e-47
Identities = 130/447 (29%), Positives = 191/447 (42%), Gaps = 41/447 (9%)
Query: 255 NCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG-EM 313
+C + + VC+ C CD G + C VP + C + G E
Sbjct: 3167 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC---VPLNNGCGCWANGTYHEAGSEF 3223
Query: 314 WSSINCTI-CACVKGRTECRNKQCIPISSCPQGKILN-----RKGCCPICTEKPGVCTVF 367
W+ C+ C C G C P +SC G++ + GC P+ T + C +
Sbjct: 3224 WADGTCSQWCRCGPGGGSL---VCTP-ASCGLGEVCGLLPSGQHGCQPVSTAE---CQAW 3276
Query: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSP---ASPFQVLVKNDARRTRSFSWTKSVELV 424
GDPHY T DG F+FQGTC+Y+L+ C P A F V V N+ R +++ S+T+SV L
Sbjct: 3277 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQ 3336
Query: 425 LGESRVSLQQHLTVRW------NGSRIALPCRAPHF-HIDLDGYLLKVTTKAGLEISWDG 477
+ ++L + RW +G + LP + H L G + VTT +GL +++DG
Sbjct: 3337 IYNHSLTL----SARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 3392
Query: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
DSFV + G LCGLCGNYN DDL G W+V + C
Sbjct: 3393 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 3444
Query: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
KP P C + C + + + CH V A +++ C+ D C+ H
Sbjct: 3445 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHP 3504
Query: 596 NCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPC 655
C + Y ACQ G ++ + + QC + Y+ CG C +C + + C
Sbjct: 3505 GGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC 3564
Query: 656 NKPCVAGCHCPANLVLHKGRCIKPVLC 682
C GC C A VL C+ C
Sbjct: 3565 ESACREGCVCDAGFVLSGDTCVPVGQC 3591
Score = 185 bits (469), Expect = 1e-46
Identities = 132/448 (29%), Positives = 191/448 (42%), Gaps = 43/448 (9%)
Query: 255 NCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG-EM 313
+C + + VC+ C CD G + C VP + C + G E
Sbjct: 4368 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC---VPLNNGCGCWANGTYHEAGSEF 4424
Query: 314 WSSINCTI-CACVKGRTECRNKQCIPISSCPQGKILN-----RKGCCPICTEKPGVCTVF 367
W+ C+ C C G C P +SC G++ + GC P+ T + C +
Sbjct: 4425 WADGTCSQWCRCGPGGGSL---VCTP-ASCGLGEVCGLLPSGQHGCQPVSTAE---CQAW 4477
Query: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSP---ASPFQVLVKNDARRTRSFSWTKSVELV 424
GDPHY T DG F+FQGTC+Y+L+ C P A F V V N+ R +++ S+T+SV L
Sbjct: 4478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQ 4537
Query: 425 LGESRVSLQQHLTVRW------NGSRIALPCRAPHF-HIDLDGYLLKVTTKAGLEISWDG 477
+ ++L + RW +G +ALP + H L G + VTT +GL +++DG
Sbjct: 4538 IYNHSLTL----SARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 4593
Query: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
DSFV + LCGLCGNYN DDL G W+V + C
Sbjct: 4594 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 4645
Query: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
KP P C + C + + + CH V A +++ C+ D C+ H
Sbjct: 4646 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHP 4705
Query: 596 NCYCESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
C + Y ACQ G ++ W C QC + Y+ CG C +C + +
Sbjct: 4706 GGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAPEG 4764
Query: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
C C GC C A VL C+ C
Sbjct: 4765 CESACREGCVCDAGFVLSGDTCVPVGQC 4792
Score = 172 bits (436), Expect = 9e-43
Identities = 141/497 (28%), Positives = 208/497 (41%), Gaps = 65/497 (13%)
Query: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR 262
CP LSCP + + G CP SC NG++ NC+ C
Sbjct: 741 CP-LSCPANSRYELCGPACPT-------------SC--------NGAA-APSNCSGRPCV 777
Query: 263 DSTVVCKRKCSHPGGCDQGQE-GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI 321
+ V + G C GC + L P + E+W+ C
Sbjct: 778 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQ---------------EVWADELCQR 822
Query: 322 CACVKGRTE---CRNKQCIPISSCPQGKILNRK----GCCPICTEKPGVCTVFGDPHYNT 374
G T CR+KQ SCP G+ + + GC P ++ G C GDPHY +
Sbjct: 823 RCTCNGATHQVTCRDKQ-----SCPAGERCSVQNGLLGCYP---DRFGTCQGSGDPHYVS 874
Query: 375 FDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSL 432
FDGR F+F GTC Y+L C A+ F+VLV+N+ R +++ S+T++V + +V++
Sbjct: 875 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAV 934
Query: 433 QQHLT--VRWNGSRIALPCRAPHFHIDL--DGYLLKVTTKAGLEISWDGDSFVEVMAAPH 488
++ V + LP +A + + G V T GL +++D ++ V
Sbjct: 935 RREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSS 994
Query: 489 LKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQG 548
LCGLCGN+NG DDL G + F SW+ E+ C + P+L
Sbjct: 995 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKL-DS 1053
Query: 549 TVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYT 606
V +L++ EC L + F+ CHS +D R CV D C P C++ Y
Sbjct: 1054 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1113
Query: 607 RACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHC 665
ACQ G VH W ++ C + C + Y+ C GC +C + G C C GC C
Sbjct: 1114 AACQAAGATVHPWRSEELCPLS-CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVC 1172
Query: 666 PANLVLHKGRCIKPVLC 682
L C+ C
Sbjct: 1173 DEGFALSGESCLPLASC 1189
Score = 167 bits (422), Expect = 4e-41
Identities = 135/467 (28%), Positives = 203/467 (43%), Gaps = 51/467 (10%)
Query: 254 DNCT-ACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCK-FGNKIFQDG 311
D C+ C+ + + C C+ CD G + C+ I+ C + N ++ +
Sbjct: 3945 DTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACV------PIQQCGCYHNGVYYEP 3998
Query: 312 EMWSSI-NCTI-CACVKGRTE-CRNKQCIPISSC-PQGKILN--RKGCC--------PIC 357
E I NC C C G+ C+ C P C P G IL+ K C C
Sbjct: 3999 EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETC 4058
Query: 358 TEKPG----------VCTVFGDPHYNTFDGRTFNFQGTCQYVL-TKDCSSPAS----PFQ 402
E+ G C ++GDPHY++FDGR F+FQGTC YVL T C ++ PF
Sbjct: 4059 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 4118
Query: 403 VLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLT--VRWNGSRIALPCRAPHFHIDLDG 460
V KN R + S+ + V + + +S+ + VR NG ALP I +
Sbjct: 4119 VTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQ 4178
Query: 461 YLLKVTTKA--GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFD 518
K A GL++S+D + V+V G +CGLCGN + + +D + +G
Sbjct: 4179 GASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS 4238
Query: 519 VDDFAESWRVES-NEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWE---FQTCHST 574
+ + SWR + C R P + ++ + C L S F TCH+
Sbjct: 4239 IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE-QYEGPGFCGPLSSGTGGPFTTCHAH 4297
Query: 575 VDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA 633
V +F++ CV D+C ++ C++ +Y ACQ G+ + W Q C T C +
Sbjct: 4298 VPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT-CPENS 4356
Query: 634 VYDTCGPGCIKTCDNWNEI---GPCNKPCVAGCHCPANLVLHKGRCI 677
Y+ CGP C +C + + C PCV GC C A VL RC+
Sbjct: 4357 HYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 4403
Score = 165 bits (418), Expect = 1e-40
Identities = 108/363 (29%), Positives = 155/363 (42%), Gaps = 18/363 (4%)
Query: 331 CRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVL 390
C QC C +++ K C E VC GDPHY TFDGR ++ GTC Y +
Sbjct: 444 CEGMQCAAGQRC---QVVGGKAGC--VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 498
Query: 391 TKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQ----HLTVRWNGSR 444
+ CS + F V KN+ R +R S+ V + VSL + + V SR
Sbjct: 499 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 558
Query: 445 IALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHK 504
+ + + G V GL +++D D + + + ++CGLCGNYNG
Sbjct: 559 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 618
Query: 505 RDDLIGGDGNFKFDVDDFAESWRVESNEF-CNRPQRKPVPELCQGTVKVKLRAHRECQKL 563
DD + DG D +FA SW+++ ++ C + P G + R C L
Sbjct: 619 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQ-HYEGDRLCGML 677
Query: 564 KSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEP 620
+ F CH T+D F CV D+C + C AY +AC GI V W
Sbjct: 678 TKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 737
Query: 621 QQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCN-KPCVAGCHCPANLVLHKGRCIKP 679
NC + C + Y+ CGP C +C+ C+ +PCV GC C V G C+
Sbjct: 738 PANCPLS-CPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 796
Query: 680 VLC 682
C
Sbjct: 797 SSC 799
Score = 165 bits (418), Expect = 1e-40
Identities = 134/467 (28%), Positives = 202/467 (43%), Gaps = 51/467 (10%)
Query: 254 DNCT-ACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCK-FGNKIFQDG 311
D C+ C+ + + C C+ CD G + C+ I+ C + N + +
Sbjct: 2744 DTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACV------PIQQCGCYHNGAYYEP 2797
Query: 312 EMWSSI-NCTI-CACVKGRTE-CRNKQCIPISSC-PQGKIL---NRKGCCPI-------C 357
E I NC C C G+ C+ C P C P G IL N+ C + C
Sbjct: 2798 EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETC 2857
Query: 358 TEKPG----------VCTVFGDPHYNTFDGRTFNFQGTCQYVL-TKDCSSPAS----PFQ 402
E+ G C ++GDPHY++FDGR F+FQGTC YVL T C ++ PF
Sbjct: 2858 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 2917
Query: 403 VLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLT--VRWNGSRIALPCRAPHFHIDLDG 460
V KN R + S+ + V + + +S+ + VR NG ALP I +
Sbjct: 2918 VTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQ 2977
Query: 461 YLLKVTTKA--GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFD 518
K A GL++S+D + V+V G +CGLCGN + + +D + +G
Sbjct: 2978 GASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS 3037
Query: 519 VDDFAESWRVES-NEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLK---SWEFQTCHST 574
+ + SWR + C R P + ++ + C L F TCH+
Sbjct: 3038 IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE-QYEGPGFCGPLAPGTGGPFTTCHAH 3096
Query: 575 VDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA 633
V +F++ CV D+C ++ C++ +Y ACQ G+ + W Q C T C +
Sbjct: 3097 VPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT-CPENS 3155
Query: 634 VYDTCGPGCIKTCDNWNEI---GPCNKPCVAGCHCPANLVLHKGRCI 677
Y+ CGP C +C + + C PCV GC C A VL RC+
Sbjct: 3156 HYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 3202
Score = 162 bits (410), Expect = 1e-39
Identities = 137/469 (29%), Positives = 200/469 (42%), Gaps = 60/469 (12%)
Query: 261 CRDSTVVCKRKCSHPGGCDQGQEGCCEECLLR----------VPPEDIKVCK-FGNKIFQ 309
C D+ C CS Q Q+GC E C VP I+ C + N ++
Sbjct: 1541 CADT---CSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVP---IQQCGCYHNGVYY 1594
Query: 310 DGEMWSSI-NCTI-CACVKGR-TECRNKQCIPISSC-PQGKILN--RKGCC--------P 355
+ E I NC C C G+ C+ C P C P G IL+ K C
Sbjct: 1595 EPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQE 1654
Query: 356 ICTEKPG----------VCTVFGDPHYNTFDGRTFNFQGTCQYVL-TKDCSSPAS----P 400
C E+ G C ++GDPHY++FDGR F+FQGTC YVL T C ++ P
Sbjct: 1655 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 1714
Query: 401 FQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLT--VRWNGSRIALPCRAPHFHIDL 458
F V KN R + S+ + V + + +S+ + VR NG ALP I +
Sbjct: 1715 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 1774
Query: 459 DGYLLKVTTKA--GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFK 516
K A GL++S+D + V+V G +CGLCGN + + +D + +G
Sbjct: 1775 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 1834
Query: 517 FDVDDFAESWRVES-NEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLK---SWEFQTCH 572
+ + SWR + C R P + ++ + C L F TCH
Sbjct: 1835 PSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE-QYEGPGFCGPLAPGTGGPFTTCH 1893
Query: 573 STVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKH 631
+ V +F++ CV D+C ++ C++ +Y ACQ G+ + W Q C T C
Sbjct: 1894 AHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT-CPE 1952
Query: 632 GAVYDTCGPGCIKTCDNWNEI---GPCNKPCVAGCHCPANLVLHKGRCI 677
+ Y+ CG C +C + + C PCV GC C A VL RC+
Sbjct: 1953 NSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 2001
Score = 153 bits (387), Expect = 4e-37
Identities = 124/440 (28%), Positives = 185/440 (42%), Gaps = 41/440 (9%)
Query: 261 CRDSTVVCKRKCSHPGGCDQG-QEGC-CEECLLRVPPEDIKV----CKFGNKIFQDGEM- 313
C DS V S P GC+ +EGC C+ + + V C + + GE+
Sbjct: 4748 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 4807
Query: 314 WSSINCTI-CACVKG-RTECRN-KQCIPISSCPQG---KILNRKGCCPICTEKPGVCTVF 367
+ C C C G C+ C P C + + GC G C
Sbjct: 4808 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC--------GRCLAN 4859
Query: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQ---VLVKNDARRTRSFSWTKSVELV 424
G HY T DGR ++ G+C YVL + C VL KN A + T + ++V
Sbjct: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVV 4919
Query: 425 LGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVM 484
SL Q V +G +ALP + +G + + T GL + +DGD+ + +
Sbjct: 4920 ------SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMS 4973
Query: 485 AAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVE-SNEFCNR---PQRK 540
+G+LCGLCGN+NG+ DD + +G+ V+ F +WR S++ C PQ
Sbjct: 4974 IPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGC 5033
Query: 541 PVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCY 598
PV C ++ C +L++ + F TC + + + ++R CV D+C K
Sbjct: 5034 PV---CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 5090
Query: 599 CESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNK 657
C S AYT ACQ G+ V W C C + Y C C +C + + C
Sbjct: 5091 CRSLAAYTAACQAAGVAVKPWRTDSFC-PLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 5149
Query: 658 PCVAGCHCPANLVLHKGRCI 677
C GC C +L +G CI
Sbjct: 5150 RCFEGCECDDRFLLSQGVCI 5169
Score = 151 bits (381), Expect = 2e-36
Identities = 135/501 (26%), Positives = 198/501 (39%), Gaps = 64/501 (12%)
Query: 201 EVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPF-GSCLFRSDVYDNGSSFLYDNCTAC 259
E+CP LSCP H + CP G DLP G C S+ ++ C
Sbjct: 1130 ELCP-LSCPPHSHYEACSYGCPLSCG-----DLPVPGGC--GSECHEG-----------C 1170
Query: 260 TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINC 319
C + + C C GC + P + F G S+
Sbjct: 1171 VCDEGFALSGESCLPLASC-----GCVHQGTYHPP----------GQTFYPGPGCDSL-- 1213
Query: 320 TICACVKGR-TECRNKQCIPISSC-PQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDG 377
C C +G C + C P +C P G L GC + + C GDPHY TFDG
Sbjct: 1214 --CHCQEGGLVSCESSSCGPHEACQPSGGSL---GCVAVGSS---TCQASGDPHYTTFDG 1265
Query: 378 RTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQH 435
R F+F GTC YVL + C + F VL +N A S T+ + + + + L+Q
Sbjct: 1266 RRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR 1325
Query: 436 L-TVRWNGSRIALPCRAPHFHIDLD--GYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGK 492
V NG + LP + I G + + T GL +++D +V V + +
Sbjct: 1326 QWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQ 1385
Query: 493 LCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR-VESNEFCNRPQRKP------VPE- 544
+CGLCGNYNG +DD +G+ + ++F SW V + C P P +P
Sbjct: 1386 MCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSH 1445
Query: 545 LCQGTVKVKLRAHRECQKLKS--WEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESF 602
C ++ K + C L S +CH VD + C+ D+C + + C +
Sbjct: 1446 KCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNI 1505
Query: 603 LAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVA 661
AY ACQ G V W + C +C + Y+ C C C + C C
Sbjct: 1506 HAYVSACQAAGGHVEPWRTETFCPM-ECPPNSHYELCADTCSLGCSALSAPPQCQDGCAE 1564
Query: 662 GCHCPANLVLHKGRCIKPVLC 682
GC C + + + C+ C
Sbjct: 1565 GCQCDSGFLYNGQACVPIQQC 1585
Score = 147 bits (371), Expect = 3e-35
Identities = 124/448 (27%), Positives = 188/448 (41%), Gaps = 33/448 (7%)
Query: 261 CRDSTVVCKRKCSHPGGCDQG-QEGC-CEECLLRVPPEDIKV----CKFGNKIFQDGE-M 313
C DS S P GC+ +EGC C+ + + V C ++ + G+
Sbjct: 2346 CGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTF 2405
Query: 314 WSSINC-TICACVKG-RTECRNKQCIPISSC-PQGKILNRKGCCPICTEKPGVCTVFGDP 370
+ C ++C C +G C C P +C P G L GC + + C GDP
Sbjct: 2406 YPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSL---GCVAVGST---TCQASGDP 2459
Query: 371 HYNTFDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGES 428
HY TFDGR F+F GTC YVL + C + F VL +N A S T+ + + +
Sbjct: 2460 HYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 2519
Query: 429 RVSLQQHL-TVRWNGSRIALPCRAPHFHIDLD--GYLLKVTTKAGLEISWDGDSFVEVMA 485
+ L+Q V NG + LP + I G + + T GL +++D +V V
Sbjct: 2520 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV 2579
Query: 486 APHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR-VESNEFCNRPQRKP--- 541
+ +CGLCGNYNG +DD +G+ + ++F SW V + C P P
Sbjct: 2580 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 2639
Query: 542 ---VP-ELCQGTVKVKLRAHRECQKLKS--WEFQTCHSTVDYATFYRSCVTDMCECPVHK 595
+P E C ++ K + C L S +CH VD + C+ D+C +
Sbjct: 2640 EGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 2699
Query: 596 NCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
+ C + AY ACQ G +V W + C +C + Y+ C C C +
Sbjct: 2700 SILCSNIHAYVSACQAAGGQVEPWRNETFCPM-ECPQNSHYELCADTCSLGCSALSAPLQ 2758
Query: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
C C GC C + + + C+ C
Sbjct: 2759 CPDGCAEGCQCDSGFLYNGQACVPIQQC 2786
Score = 144 bits (362), Expect = 4e-34
Identities = 122/448 (27%), Positives = 186/448 (41%), Gaps = 33/448 (7%)
Query: 261 CRDSTVVCKRKCSHPGGCDQG-QEGC-CEECLLRVPPEDIKV----CKFGNKIFQDGE-M 313
C DS S P GC+ +EGC C+ + + V C ++ + G+
Sbjct: 3547 CGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTF 3606
Query: 314 WSSINC-TICACVKG-RTECRNKQCIPISSC-PQGKILNRKGCCPICTEKPGVCTVFGDP 370
+ C ++C C +G C C P +C P G L GC + + C GDP
Sbjct: 3607 YPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSL---GCVAVGST---TCQASGDP 3660
Query: 371 HYNTFDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGES 428
HY TFDG F+F GTC YVL + C + F VL +N A S T+ + + +
Sbjct: 3661 HYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 3720
Query: 429 RVSLQQHL-TVRWNGSRIALPCRAPHFHIDLD--GYLLKVTTKAGLEISWDGDSFVEVMA 485
+ L+Q V NG + LP + I G + + T GL +++D +V V
Sbjct: 3721 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV 3780
Query: 486 APHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR-VESNEFCNRPQRKP--- 541
+ +CGLCGNYNG +DD +G+ + ++F SW V + C P P
Sbjct: 3781 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 3840
Query: 542 ---VP-ELCQGTVKVKLRAHRECQKLKS--WEFQTCHSTVDYATFYRSCVTDMCECPVHK 595
+P + C ++ K + C L S +CH VD + C+ D+C +
Sbjct: 3841 AGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 3900
Query: 596 NCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
+ C + AY ACQ G V W + C +C + Y+ C C C +
Sbjct: 3901 SILCSNIHAYVSACQAAGGHVEPWRNETFCPM-ECPQNSHYELCADTCSLGCSALSAPLQ 3959
Query: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
C C GC C + + + C+ C
Sbjct: 3960 CPDGCAEGCQCDSGFLYNGQACVPIQQC 3987
Score = 56.6 bits (135), Expect = 7e-08
Identities = 60/268 (22%), Positives = 96/268 (35%), Gaps = 25/268 (9%)
Query: 259 CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECL--------------LRVPPEDIKVCKFG 304
C +C R C G GC C + +P +D G
Sbjct: 5121 CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNG 5180
Query: 305 NKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVC 364
+ + + +S C+C + C + CP G++ K C G+C
Sbjct: 5181 RYLPVNSSLLTSDCSERCSC----SSSSGLTC-QAAGCPPGRVCEVKAEARNCWATRGLC 5235
Query: 365 TVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVE 422
+ + TFDG Y L+ C + P+ +V V
Sbjct: 5236 VLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH 5295
Query: 423 LVLGESRVSLQQHLTVRWNGSRIALPCR---APHFHIDLDGYLLKVTTKAGLEISWDGDS 479
+ + V+L + V NG R+ LP + DG LL V KAG+++ +
Sbjct: 5296 IFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLL-VRQKAGVQVWLGANG 5354
Query: 480 FVEVMAAPHLKGKLCGLCGNYNGHKRDD 507
V V+ + GKLCG CGN++G + +D
Sbjct: 5355 KVAVIVSNDHAGKLCGACGNFDGDQTND 5382
Score = 34.7 bits (78), Expect = 0.30
Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 33/140 (23%)
Query: 100 ACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMC 159
AC C G N C R C EG V G + G C
Sbjct: 757 ACPTSCNGAAAPSN--------------CSGRPCVEGCVCLPGF---------VASGGAC 793
Query: 160 CPTCP-GCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPG 218
P GC F+G+Q G+E + +C+C G Q ++C S P G
Sbjct: 794 VPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQ--------VTCRDKQS-CPAG 844
Query: 219 QCCPKCLGQRKVFDLPFGSC 238
+ C G + FG+C
Sbjct: 845 ERCSVQNGLLGCYPDRFGTC 864
Score = 31.6 bits (70), Expect = 2.5
Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 22/94 (23%)
Query: 127 PCVLR-QCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEG-- 183
PCV QC G V S RCV PL + C GC G ++ G EF +G
Sbjct: 1982 PCVEGCQCDAGFVL-SADRCV-----PLNN------GC-GCWANGTYHEAGSEFWADGTC 2028
Query: 184 SKCTKCSCTGGRTQC------VREVCPILSCPQH 211
S+ +C GG C + EVC +L QH
Sbjct: 2029 SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 2062
Score = 31.6 bits (70), Expect = 2.5
Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 22/94 (23%)
Query: 127 PCVLR-QCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEG-- 183
PCV QC G V S RCV PL + C GC G ++ G EF +G
Sbjct: 3183 PCVEGCQCDAGFVL-SADRCV-----PLNN------GC-GCWANGTYHEAGSEFWADGTC 3229
Query: 184 SKCTKCSCTGGRTQC------VREVCPILSCPQH 211
S+ +C GG C + EVC +L QH
Sbjct: 3230 SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 3263
Score = 31.6 bits (70), Expect = 2.5
Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 22/94 (23%)
Query: 127 PCVLR-QCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEG-- 183
PCV QC G V S RCV PL + C GC G ++ G EF +G
Sbjct: 4384 PCVEGCQCDAGFVL-SADRCV-----PLNN------GC-GCWANGTYHEAGSEFWADGTC 4430
Query: 184 SKCTKCSCTGGRTQC------VREVCPILSCPQH 211
S+ +C GG C + EVC +L QH
Sbjct: 4431 SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 4464
Score = 31.6 bits (70), Expect = 2.5
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 133 CQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKC-TKCSC 191
C+EG V ++G V + +G C GC+ +G Y GE F P G +C +C C
Sbjct: 4769 CREGCVCDAGF---VLSGDTCVPVGQC-----GCLHDGRYYPLGEVFYP-GPECERRCEC 4819
Query: 192 -TGGRTQC 198
GG C
Sbjct: 4820 GPGGHVTC 4827
Score = 30.4 bits (67), Expect = 5.7
Identities = 21/73 (28%), Positives = 28/73 (38%), Gaps = 9/73 (12%)
Query: 132 QCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSC 191
+C EG V + G PL +C GCV +G + G+ F P + C C
Sbjct: 1165 ECHEGCVCDEGFALSGESCLPLA-------SC-GCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
Query: 192 -TGGRTQCVREVC 203
GG C C
Sbjct: 1217 QEGGLVSCESSSC 1229
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 186 bits (473), Expect = 5e-47
Identities = 151/554 (27%), Positives = 213/554 (38%), Gaps = 92/554 (16%)
Query: 145 CVVHCKNPLEHL----GMCCPT--CPGCVFEGVQYQEGEEFQPEGSKCTKCSCTG-GRTQ 197
CV C PL L G C P CP C +Y G E C +C C G
Sbjct: 856 CVAGCNCPLGLLWDPEGQCVPPSLCP-CQLGARRYAPGSATMKE---CNRCICQERGLWN 911
Query: 198 CVREVCPILS-CPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNC 256
C CP + CP+ L + P G+CL D S +
Sbjct: 912 CTARHCPSQAFCPRELVYAP-------------------GACLLTCDSPSANHSCPAGST 952
Query: 257 TACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSS 316
C C TV+ +C VPP D+ C+ + +
Sbjct: 953 DGCVCPPGTVLLDERC--------------------VPP-DLCPCRHSGQWYLPNATIQE 991
Query: 317 INCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFD 376
+C +C C + C ++ + G C G PHY TFD
Sbjct: 992 -DCNVCVCRGRQWHCTGQR------------------------RSGRCQASGAPHYVTFD 1026
Query: 377 GRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHL 436
G F + G C+Y+L ++ S F V +N + TK++ + L + V + +
Sbjct: 1027 GLAFTYPGACEYLLVREASGL---FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGR 1083
Query: 437 TVRWNGSRIALP--CRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLC 494
V NG + P P + G L ++T GL + WDG + V V +P +G++
Sbjct: 1084 AVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVA 1143
Query: 495 GLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKL 554
GLCG+++G +DL G + + A SWR+ + C P P P C
Sbjct: 1144 GLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL--SPLCPEPGDLPHP--CTMNTHRAG 1199
Query: 555 RAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKN--CYCESFLAYTRACQRE 612
A C L F CH+ V Y C+ D C C + C C + Y C R
Sbjct: 1200 WARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARH 1259
Query: 613 GIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTC-DNWNEIG-PCN-KPCVAGCHCPANL 669
G V W Q+ C + QC+ G VY+ CGP C TC + E G C CV GC CP
Sbjct: 1260 GHHVRWRSQELC-SLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGT 1318
Query: 670 VLHKGRCIKPVLCP 683
+LH G C++P CP
Sbjct: 1319 LLHGGACLEPASCP 1332
Score = 148 bits (374), Expect = 1e-35
Identities = 119/447 (26%), Positives = 176/447 (39%), Gaps = 68/447 (15%)
Query: 263 DSTVVCKRKCSHPGGCDQGQEGCC-EECL--------------LRVPPEDIKVCKFGNKI 307
D +C C G QG+E C EEC+ L VP C + +
Sbjct: 477 DCVSLCPPSCEAVG---QGEEESCREECVSGCECPRGLFWNGTLCVPAAHCP-CYYCRQR 532
Query: 308 FQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVF 367
+ G+ + C C C GR C C P C V
Sbjct: 533 YVPGDTVRQL-CNPCVCRDGRWHCAQALC------------------------PAECAVG 567
Query: 368 GDPHYNTFDGRTFNFQGT--CQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVL 425
GD HY TFDGR+++F G C+Y L +D Q+L+ + + S ++ + L
Sbjct: 568 GDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKG----QLLILLEHGACDAGSCLHAISVSL 623
Query: 426 GESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDG-------- 477
++ + L+ V NG + LP I +G ++ + A L + W G
Sbjct: 624 EDTHIQLRDSGAVLVNGQDVGLPW------IGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
Query: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
D + P ++ GLCG + +++DD + G+ + + FA ++V C
Sbjct: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPS- 736
Query: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNC 597
+ + C + A C L S FQ CH VD FY C+ +C C +C
Sbjct: 737 EDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDC 796
Query: 598 YCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNK 657
C AY R C +EG W Q C C G Y C P C + C + G
Sbjct: 797 LCPVLSAYARRCAQEGASPPWRNQTLC-PVMCPGGQEYRECAPACGQHCGKPEDCGELGS 855
Query: 658 PCVAGCHCPANLVLH-KGRCIKPVLCP 683
CVAGC+CP L+ +G+C+ P LCP
Sbjct: 856 -CVAGCNCPLGLLWDPEGQCVPPSLCP 881
Score = 101 bits (252), Expect = 2e-21
Identities = 84/355 (23%), Positives = 131/355 (36%), Gaps = 59/355 (16%)
Query: 364 CTVFGDPHYNTFDGRTFNFQGTCQYVLT--------------KDCSSPASPFQVLVKNDA 409
C + HY TFDGR ++F G C Y+L C P +V + +
Sbjct: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVTMGPEE 254
Query: 410 RRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKA 469
++ + + +LV E + L L+++W G + L +
Sbjct: 255 VLIQAGNVSVKGQLV-PEGQSWLLHGLSLQWLGDWLVL------------------SGGL 295
Query: 470 GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVE 529
G+ + D + + L G+ GLCG YNG DD + G F SWR+
Sbjct: 296 GVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLP 355
Query: 530 SNEFCNRPQRKPVPELCQGTVKVKL------------RAHRECQKLKSWEFQTCHSTVDY 577
+E E+ QG + L A C +L F CH+ V
Sbjct: 356 GSE----SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSP 411
Query: 578 ATFYRSCVTDMCECPV-------HKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCK 630
A ++ +C+ C + + C +F +Y +AC R I + W C C
Sbjct: 412 AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERL-CP 470
Query: 631 HGAVYDTCGPGCIKTCD--NWNEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
G +Y C C +C+ E C + CV+GC CP L + C+ CP
Sbjct: 471 GGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCP 525
Score = 66.6 bits (161), Expect = 7e-11
Identities = 80/328 (24%), Positives = 113/328 (34%), Gaps = 69/328 (21%)
Query: 67 CIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA- 125
C C C+N+ + C ++CPVL A + +C C G T E + +P
Sbjct: 4746 CQNCTCVNESLVCPHQECPVLGPWSAWS-----SCSAPCGGGTMERHRTCEGGPGVAPCQ 4800
Query: 126 -------EPCVLRQCQEGVVTESGVRCVVHCKNPLEHL--GMCC---PTCPGCVFEGVQ- 172
+ C L+ C E + C C HL G C P PGC G Q
Sbjct: 4801 AQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQL 4860
Query: 173 YQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPG----QCCPKCLGQR 228
G P CT+ S G T L+ + +PPG + C +C+
Sbjct: 4861 LHNGTCVPPTACPCTQHSLPWGLT---------LTLEEQAQELPPGTVLTRNCTRCVCHG 4911
Query: 229 KVFDLPFGSC-----------------LFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRK 271
F C L + ++ NC+ + R S VC+
Sbjct: 4912 GAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCS--SARASGCVCQ-- 4967
Query: 272 CSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTEC 331
G + Q G C PED C + G W C C C+ GR C
Sbjct: 4968 ----PGHFRSQAGPC-------VPEDHCECWHLGRPHLPGSEWQEA-CESCLCLSGRPVC 5015
Query: 332 RNKQCIPISSCPQGK--ILNRKGCCPIC 357
+ C P+ +C QG+ +L CCP C
Sbjct: 5016 -TQHCSPL-TCAQGEEMVLEPGSCCPSC 5041
Score = 51.2 bits (121), Expect = 3e-06
Identities = 36/132 (27%), Positives = 49/132 (37%), Gaps = 23/132 (17%)
Query: 557 HRECQKLKSWE-FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIK 615
H+EC L W + +C + T R H+ C +A CQ +
Sbjct: 4760 HQECPVLGPWSAWSSCSAPCGGGTMER-----------HRTCEGGPGVA---PCQAQDT- 4804
Query: 616 VHWEPQQNC---AATQCKHGAVYDTCGPGCIKTCDNWNEIGPC-NKPCVAGCHCPANLVL 671
E +Q C +C G V C C C + C +PC GC CP +L
Sbjct: 4805 ---EQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLL 4861
Query: 672 HKGRCIKPVLCP 683
H G C+ P CP
Sbjct: 4862 HNGTCVPPTACP 4873
Score = 50.4 bits (119), Expect = 5e-06
Identities = 61/257 (23%), Positives = 83/257 (32%), Gaps = 35/257 (13%)
Query: 45 GSVAKCENEGEVLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDC--ALAIKQRGACC 102
G E + + L + C CVC +C C V + +A + G C
Sbjct: 4882 GLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCE 4941
Query: 103 EQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPT 162
+ C N S + A CV CQ G CV HLG P
Sbjct: 4942 QTCLEMNATKTQSNCS---SARASGCV---CQPGHFRSQAGPCVPEDHCECWHLGR--PH 4993
Query: 163 CPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCP 222
PG ++QE C C C GR C + P+ + PG CCP
Sbjct: 4994 LPGS-----EWQEA---------CESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCP 5039
Query: 223 KCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYD-NCTACT--CRDSTVVCKRKCSHPGGCD 279
C + P L + G+ +L + C+ C ST V + CD
Sbjct: 5040 SCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCD 5099
Query: 280 QGQEGCCEECLLRVPPE 296
CC R+ PE
Sbjct: 5100 -----CCS---YRLDPE 5108
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/87 (34%), Positives = 38/87 (43%), Gaps = 13/87 (14%)
Query: 598 YCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNK 657
YCE A CQ P NC A + GA Y CGP C ++CD ++ C
Sbjct: 3290 YCEGPRAQGEVCQALPC-----PVTNCTAIE---GAEYSPCGPPCPRSCD---DLVHCVW 3338
Query: 658 PCVAGCHCPANLVLHKGR--CIKPVLC 682
C GC+CP VL C++P C
Sbjct: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHC 3365
Score = 45.1 bits (105), Expect = 2e-04
Identities = 52/208 (25%), Positives = 69/208 (33%), Gaps = 49/208 (23%)
Query: 133 CQEGVVTESGVRCVVHCKNPLEHLGMCCPT--CPGCVFEGVQYQEGEEFQPEGSKCTKCS 190
CQ+ V + G RC K LE G C P C +G + G + Q C CS
Sbjct: 4088 CQDDQVCQKGCRCP---KGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQ---DACNNCS 4141
Query: 191 CTGGRTQCVREVCPILSCPQHL--SHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNG 248
C G+ C + CP P H SH C G R FRS +G
Sbjct: 4142 CQAGQLSCTAQPCP---PPTHCAWSHWSAWSPCSHSCGPRG------QQSRFRSST--SG 4190
Query: 249 SSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIF 308
S A CR+ +Q Q C + P +C G +
Sbjct: 4191 S-------WAPECRE---------------EQSQSQPCPQ------PSCPPLCLQGTRSR 4222
Query: 309 QDGEMWSSINCTICACVKGRTECRNKQC 336
G+ W C C+C C + +C
Sbjct: 4223 TLGDSWLQGECQRCSCTPEGVICEDTEC 4250
Score = 44.3 bits (103), Expect = 4e-04
Identities = 29/81 (35%), Positives = 34/81 (41%), Gaps = 11/81 (13%)
Query: 609 CQREGIKVHWEPQQNCAATQCKHGAVYD---TCGPG-CIKTCDNWNEIGPCNKPCVAGCH 664
CQ G+ W NC A C A PG C+ TCD+ + C GC
Sbjct: 904 CQERGL---W----NCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCV 956
Query: 665 CPANLVLHKGRCIKPVLCPQR 685
CP VL RC+ P LCP R
Sbjct: 957 CPPGTVLLDERCVPPDLCPCR 977
Score = 44.3 bits (103), Expect = 4e-04
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 8/70 (11%)
Query: 622 QNCAA-TQCKHGAVY---DTCGPG----CIKTCDNWNEIGPCNKPCVAGCHCPANLVLHK 673
Q C+ T C+ G VY D C G C +C + C+ CV GC CP L+LH
Sbjct: 2607 QPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHD 2666
Query: 674 GRCIKPVLCP 683
RC+ CP
Sbjct: 2667 TRCLPLSECP 2676
Score = 42.4 bits (98), Expect = 0.001
Identities = 67/302 (22%), Positives = 100/302 (33%), Gaps = 81/302 (26%)
Query: 108 CTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCV 167
C +G +++ W +EPC G +T C +P ++ G C PG
Sbjct: 1747 CPVDGE-WSTWSPWSVCSEPC------RGTMTRQR-----QCHSP-QNGGRTCAALPG-- 1791
Query: 168 FEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPI--------LSCPQHLSHIPPGQ 219
G+ + P+ C +C+G CP+ ++CP PG
Sbjct: 1792 --GLHSTRQTKPCPQDG-CPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGC 1848
Query: 220 CCPK---------CLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDS------ 264
CP+ C+ R+ CL Y G D C C C+D
Sbjct: 1849 WCPEGQVLGSEGWCVWPRQC------PCLVDGARYWPGQRIKAD-CQLCICQDGRPRRCR 1901
Query: 265 -----TVVCK-------RKCSHPGGCDQGQ-----------EGCCEEC------LLRVPP 295
V C KC P G Q G +C R
Sbjct: 1902 LNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQT 1961
Query: 296 EDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKIL---NRKG 352
E + C+ ++ + GE W C +C C+ T + C P+ SCPQG +L +
Sbjct: 1962 EPCEGCEHQGQVHRVGERWHGGPCRVCQCLHNLTAHCSPYC-PLGSCPQGWVLVEGTGES 2020
Query: 353 CC 354
CC
Sbjct: 2021 CC 2022
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 622 QNCAATQCKHGAVYDTCGPG--CIKTCDN-WNEIGPCNKPCVAGCHCPANLVLHKGRCIK 678
Q C C G +Y C PG C +C + ++G ++ C GCHCP H+ C++
Sbjct: 3690 QVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQ 3749
Query: 679 PVLC 682
C
Sbjct: 3750 ECPC 3753
Score = 41.2 bits (95), Expect = 0.003
Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 2/62 (3%)
Query: 623 NCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNK--PCVAGCHCPANLVLHKGRCIKPV 680
NC+ C + CG C C C PC GC+CP L+ G CI P
Sbjct: 4417 NCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
Query: 681 LC 682
C
Sbjct: 4477 EC 4478
Score = 40.8 bits (94), Expect = 0.004
Identities = 28/116 (24%), Positives = 41/116 (35%), Gaps = 26/116 (22%)
Query: 159 CCPTCPGCVFEGVQYQEGEEFQPEGSKCTK-CSCTGGRTQCVREVCPILSCPQHL----- 212
C CP E + ++ E+ EG C + C G +C P +CP L
Sbjct: 2882 CTAQCP----ENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNA 2937
Query: 213 SHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVC 268
S +P QC C +Y +G+ D+C CTC + C
Sbjct: 2938 SCLPRSQC----------------PCQLHGQLYASGAMARLDSCNNCTCVSGKMAC 2977
Score = 40.8 bits (94), Expect = 0.004
Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 7/76 (9%)
Query: 613 GIKVHWEPQQNCAATQCKHGAVYDT-----CGPGCIKTC-DNWNEIGPCNKPCVAGCHCP 666
G + W Q++C C DT C C +C D W+ + PC GC CP
Sbjct: 4649 GCREPWA-QESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCP 4707
Query: 667 ANLVLHKGRCIKPVLC 682
++ GRC+ C
Sbjct: 4708 PGQLVQDGRCVPISSC 4723
Score = 39.7 bits (91), Expect = 0.009
Identities = 72/327 (22%), Positives = 102/327 (31%), Gaps = 83/327 (25%)
Query: 67 CIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAE 126
C C CL + C CPV C + + C + C+G T + + Q
Sbjct: 3388 CNHCTCLEGRLNCTDLPCPVPGGWCPWS--EWTMCSQPCRGQTRSRSRACACPTPQHGGA 3445
Query: 127 PCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKC 186
PC G E+G +H CP+ C +G G S C
Sbjct: 3446 PCT------GEAGEAGA----------QHQREACPSYATCPVDGAWGPWGP-----WSPC 3484
Query: 187 TKCSCTGGRTQ-CVREVCPILSCPQHLSHIPPGQC------CPKCLGQRKVFDLPFGSCL 239
C R++ C R P P +H C C C G + + P G
Sbjct: 3485 DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLH--PCGQPC 3542
Query: 240 FRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIK 299
RS D C+ +V C+ C P G Q+G C VPP +
Sbjct: 3543 PRS---------CQDLSPGSVCQPGSVGCQPTCGCPLG-QLSQDGLC------VPPAHCR 3586
Query: 300 VCKFGNKIFQDGEM----------------WSSIN--------CTICACVKGRTECRNKQ 335
C++ Q G M W S+ C C CV G +C+
Sbjct: 3587 -CQY-----QPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQE-- 3638
Query: 336 CIPISSCPQGKILNRKGCCPICTEKPG 362
+ CP + + G C+ G
Sbjct: 3639 ---VPDCPDPGVWSSWGPWEDCSVSCG 3662
Score = 39.3 bits (90), Expect = 0.012
Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
Query: 620 PQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPC--NKPCVA-GCHCPANLVL-HKGR 675
PQ C C ++ C P C TCD+ + C + PC + GC CP VL +G
Sbjct: 1803 PQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGW 1861
Query: 676 CIKPVLCP 683
C+ P CP
Sbjct: 1862 CVWPRQCP 1869
Score = 38.1 bits (87), Expect = 0.027
Identities = 32/123 (26%), Positives = 42/123 (34%), Gaps = 17/123 (13%)
Query: 88 SRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVV 147
+RDC C QC E + S+ + PC +G E C
Sbjct: 2874 TRDC-----NTQPCTAQCP----ENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAP 2924
Query: 148 HCKNP---LEHLGMCCPT--CPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREV 202
C P H C P CP C G Y G + + C C+C G+ C E
Sbjct: 2925 GCTCPPGLFLHNASCLPRSQCP-CQLHGQLYASGAMARLDS--CNNCTCVSGKMACTSER 2981
Query: 203 CPI 205
CP+
Sbjct: 2982 CPV 2984
Score = 38.1 bits (87), Expect = 0.027
Identities = 73/322 (22%), Positives = 97/322 (30%), Gaps = 81/322 (25%)
Query: 65 NPCIMCVCLN-KEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQS 123
+PC MC+ + + C R P R C Q C E CT G +
Sbjct: 3482 SPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSL----HP 3537
Query: 124 PAEPCVLRQCQE---GVVTESG-VRCVVHCKNPLEHL---GMCCPTC-------PGCV-- 167
+PC R CQ+ G V + G V C C PL L G+C P PG +
Sbjct: 3538 CGQPCP-RSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGI 3596
Query: 168 ------FEGVQYQEGEEFQPEG---SKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPG 218
G ++ E +P C C+C G QC + P P S P
Sbjct: 3597 PENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQC--QEVPDCPDPGVWSSWGPW 3654
Query: 219 QCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTC---RDSTVVCKRKCSHP 275
+ C G G C C + C +
Sbjct: 3655 EDCSVSCG--------------------GGEQLRSRRCARPPCPGPARQSRTCSTQVCRE 3694
Query: 276 GGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQ 335
GC G+ EC P E C F CA V + C ++
Sbjct: 3695 AGCPAGR--LYREC---QPGEG---CPFS-----------------CAHVTQQVGCFSEG 3729
Query: 336 CIPISSCPQGKILNRKGCCPIC 357
C CP+G +R C C
Sbjct: 3730 CEEGCHCPEGTFQHRLACVQEC 3751
Score = 37.7 bits (86), Expect = 0.036
Identities = 37/146 (25%), Positives = 53/146 (36%), Gaps = 12/146 (8%)
Query: 87 LSRDCALAIKQRGAC--CEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVR 144
+ DC L I Q G C C + ++S W PC + Q + + R
Sbjct: 1883 IKADCQLCICQDGRPRRCRLNPDCAVDCG-WSSWSPWAKCLGPCGSQSIQWSFRSSNNPR 1941
Query: 145 CVVH---CKNPLEHLGMCCPT--CPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCV 199
C+ + C T C GC +G ++ GE + G C C C T
Sbjct: 1942 PSGRGRQCRG-IHRKARRCQTEPCEGCEHQGQVHRVGERWH--GGPCRVCQCLHNLTAHC 1998
Query: 200 REVCPILSCPQHLSHIP-PGQCCPKC 224
CP+ SCPQ + G+ C C
Sbjct: 1999 SPYCPLGSCPQGWVLVEGTGESCCHC 2024
Score = 37.7 bits (86), Expect = 0.036
Identities = 41/152 (26%), Positives = 56/152 (36%), Gaps = 42/152 (27%)
Query: 127 PCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKC 186
PC L+ C G E G V+ L G+ P P C+ P+ ++
Sbjct: 2603 PCGLQPCSGGTDCELGR---VYVSADLCQKGLVPPCPPSCL------------DPKANR- 2646
Query: 187 TKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYD 246
SC+G CV E C PPG L + L CL ++
Sbjct: 2647 ---SCSG---HCV-EGC----------RCPPGLL----LHDTRCLPLSECPCLVGEELKW 2685
Query: 247 NGSSFLYDNCTACTCRDSTVVCKRKCSHPGGC 278
G SFL NC+ C C ++C+ PGGC
Sbjct: 2686 PGVSFLLGNCSQCVCEKGELLCQ-----PGGC 2712
Score = 37.7 bits (86), Expect = 0.036
Identities = 85/370 (22%), Positives = 121/370 (32%), Gaps = 91/370 (24%)
Query: 15 CRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIP---FITDNPCIMCV 71
CR PG LLL + +P+S + GE L+ P F+ N C CV
Sbjct: 2656 CRCPPG-----LLLHDTRCLPLSECPCLV----------GEELKWPGVSFLLGN-CSQCV 2699
Query: 72 CLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVL- 130
C E+ C+ CP+ C + A C++ G +++SP+ P
Sbjct: 2700 CEKGELLCQPGGCPL---PCGWSAWSSWAPCDRSCGSGVRA-------RFRSPSNPPAAW 2749
Query: 131 --------RQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTC--PGCVFEGVQYQEGEEFQ 180
RQ +G T G V P C +C PG G ++
Sbjct: 2750 GGAPCEGDRQELQGCHTVCGTE--VFGWTPWTSWSSCSQSCLAPG---GGPGWRSRSRLC 2804
Query: 181 PEGSKCTKCSCTGGRTQ---CVREVCPI------------LSCP---------QHLSHIP 216
P SC G TQ C VCP+ S P + S +
Sbjct: 2805 PSPGDS---SCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLA 2861
Query: 217 PGQC-CP-------KCLGQRKVFDLPFGSCLFRS--DVYDNGSSFLYDNCTACTCRDSTV 266
PG CP C Q P + LFRS + G T + T
Sbjct: 2862 PGDTTCPGPHSQTRDCNTQPCTAQCP-ENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTG 2920
Query: 267 VCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVK 326
C C+ P G C P C+ +++ G M +C C CV
Sbjct: 2921 FCAPGCTCPPGLFLHNASCL--------PRSQCPCQLHGQLYASGAMARLDSCNNCTCVS 2972
Query: 327 GRTECRNKQC 336
G+ C +++C
Sbjct: 2973 GKMACTSERC 2982
Score = 36.6 bits (83), Expect = 0.079
Identities = 53/245 (21%), Positives = 74/245 (30%), Gaps = 74/245 (30%)
Query: 13 RYCRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVC 72
R+C RSP + L P L S P + PC++ C
Sbjct: 3208 RFCARSPSAVPSTVAPLPLPATPTPLCSG------------------PEAEEEPCLLQGC 3249
Query: 73 LNKEVTCKREKCPVLSRDCALAIKQRGACCEQ---------CKGCTYEGNTYNSSFKWQS 123
SR C ++ R C+Q C+G +G
Sbjct: 3250 DRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQ------- 3302
Query: 124 PAEPCVLRQCQ--EGV-VTESGVRCVVHCKNPLEHLGMCCPTC---PGCVFE-------- 169
A PC + C EG + G C C + + + C P C PG V
Sbjct: 3303 -ALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSSNGAICVQ 3361
Query: 170 -----------GVQYQEGEEF-QPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPP 217
G ++ G +P+G C C+C GR C CP+ P
Sbjct: 3362 PGHCSCLDLLTGQRHHPGARLARPDG--CNHCTCLEGRLNCTDLPCPV-----------P 3408
Query: 218 GQCCP 222
G CP
Sbjct: 3409 GGWCP 3413
Score = 34.3 bits (77), Expect = 0.39
Identities = 20/68 (29%), Positives = 25/68 (36%), Gaps = 7/68 (10%)
Query: 622 QNCAATQCKHGAVYDTC------GPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLHKGR 675
Q C A QC ++ + G C + C C C GC CP L LH
Sbjct: 2880 QPCTA-QCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNAS 2938
Query: 676 CIKPVLCP 683
C+ CP
Sbjct: 2939 CLPRSQCP 2946
Score = 33.9 bits (76), Expect = 0.51
Identities = 16/65 (24%), Positives = 24/65 (36%), Gaps = 3/65 (4%)
Query: 621 QQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKP---CVAGCHCPANLVLHKGRCI 677
+ + T C G CG C ++C + + C C C CP + G C+
Sbjct: 3521 ENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCV 3580
Query: 678 KPVLC 682
P C
Sbjct: 3581 PPAHC 3585
Score = 33.1 bits (74), Expect = 0.88
Identities = 66/303 (21%), Positives = 98/303 (32%), Gaps = 90/303 (29%)
Query: 99 GACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVT---ESGVRCVVHCKNPLEH 155
GAC + C+ + P PC + C G E+ C C+ P
Sbjct: 4610 GACPDSCQWSLW------------GPWSPCQV-PCSGGFRLRWREAEALCGGGCREPWAQ 4656
Query: 156 LGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVC-PILSCPQHLSH 214
CP C + + Q S C+ R QC++ C P CP
Sbjct: 4657 ESCNGGPCPECEAQDTVFTLDCANQCPHS----CADLWDRVQCLQGPCRPGCRCPPG-QL 4711
Query: 215 IPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSF-------LYDNCTACTCRDSTVV 267
+ G+C +P SC R + +S+ + +C CTC + ++V
Sbjct: 4712 VQDGRC------------VPISSC--RCGLPSANASWELAPAQAVQLDCQNCTCVNESLV 4757
Query: 268 CKRK-------------CSHP-GGCDQGQEGCCE-----------------ECLLRVPPE 296
C + CS P GG + CE EC L+ PE
Sbjct: 4758 CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE 4817
Query: 297 DIKVCKFGNKIFQDGEMWSSINCTICACVKGRTE----CRNKQCIPISSCPQGKILNRKG 352
C G + S T C C+ + C + C P CP G++L+
Sbjct: 4818 ----CPPGQVL--------SACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGT 4865
Query: 353 CCP 355
C P
Sbjct: 4866 CVP 4868
Score = 32.3 bits (72), Expect = 1.5
Identities = 68/302 (22%), Positives = 105/302 (34%), Gaps = 68/302 (22%)
Query: 8 GALAERYC-RRSPGITCCVLLLLNCSGVPMSLA--SSFLTGSVAKCENEGEVLQIPFITD 64
G R C + PGI C C+ P +S L S C+ G++ +
Sbjct: 2902 GGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMAR 2961
Query: 65 -NPCIMCVCLNKEVTCKREKCPV------------LSRDCALAIKQR------------G 99
+ C C C++ ++ C E+CPV S C + I++R G
Sbjct: 2962 LDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGG 3021
Query: 100 ACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQC-----QEGVVTESGVRCVVHCKNPLE 154
A +C+G T E AE C LR C + G + V C +N
Sbjct: 3022 A---ECQGPTME-------------AEFCSLRPCPGPGGEWGPWSPCSVPCGGGYRNRTR 3065
Query: 155 ------------HLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREV 202
L C PG Q+ + + + C + S G Q
Sbjct: 3066 GSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQ---GPASCAELSAPRGTNQTCHPG 3122
Query: 203 CPILSCPQHLSHI-PPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTC 261
C S L+++ P Q CP C + ++ P GS + R + S L NC++ C
Sbjct: 3123 CHCPSGMLLLNNVCVPTQDCP-CAHEGHLY--PPGSTVVRPCENCSCVSGLIANCSSWPC 3179
Query: 262 RD 263
+
Sbjct: 3180 AE 3181
Score = 32.3 bits (72), Expect = 1.5
Identities = 11/28 (39%), Positives = 16/28 (57%)
Query: 656 NKPCVAGCHCPANLVLHKGRCIKPVLCP 683
N+ C GCHCP+ ++L C+ CP
Sbjct: 3116 NQTCHPGCHCPSGMLLLNNVCVPTQDCP 3143
Score = 30.8 bits (68), Expect = 4.3
Identities = 15/51 (29%), Positives = 21/51 (41%), Gaps = 2/51 (3%)
Query: 629 CKHGAVYDTCGPGCIKTCDNWNEIGPC--NKPCVAGCHCPANLVLHKGRCI 677
C G TC C + C + E C ++ C GC CP + G C+
Sbjct: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCV 4112
Score = 30.8 bits (68), Expect = 4.3
Identities = 23/107 (21%), Positives = 41/107 (38%), Gaps = 24/107 (22%)
Query: 262 RDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCT- 320
R++ +C C P + G C EC + + +F +++C
Sbjct: 4640 REAEALCGGGCREPWAQESCNGGPCPECEAQ------------DTVF-------TLDCAN 4680
Query: 321 ----ICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGV 363
CA + R +C C P CP G+++ C PI + + G+
Sbjct: 4681 QCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGL 4727
Score = 30.4 bits (67), Expect = 5.7
Identities = 29/114 (25%), Positives = 44/114 (38%), Gaps = 17/114 (14%)
Query: 96 KQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNP--- 152
++ G C C G G Y+ P+ V + +E E CV C+ P
Sbjct: 460 RKPGFCERLCPG----GQLYSDCVSLCPPSCEAVGQGEEESCREE----CVSGCECPRGL 511
Query: 153 LEHLGMCCPT--CPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCP 204
+ +C P CP C + +Y G+ + C C C GR C + +CP
Sbjct: 512 FWNGTLCVPAAHCP-CYYCRQRYVPGDTVR---QLCNPCVCRDGRWHCAQALCP 561
Score = 30.4 bits (67), Expect = 5.7
Identities = 67/307 (21%), Positives = 87/307 (28%), Gaps = 60/307 (19%)
Query: 99 GACCEQCK-GCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLG 157
GAC E C + N++ Q C CQEG HC H
Sbjct: 1323 GACLEPASCPCEWGRNSFPPGSVLQKDCGNCT---CQEGQW---------HCGGDGGHCE 1370
Query: 158 MCCPTCPG----------CVFEGV----QYQEGEEFQPEGSKCTKC-----SCTGGRTQC 198
P C CV G Q G+ EG C +C+ G
Sbjct: 1371 ELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLP 1430
Query: 199 VREVC------------PILSCPQHLSHIPPGQCCPK---CLGQRKVFD-LPFGSCLFRS 242
+ +C P CPQ L G+C P C G D SCL +
Sbjct: 1431 LALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQV 1490
Query: 243 DVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCK 302
S C TC + +C P G D+G C L P +
Sbjct: 1491 TCVPGEVS-----CVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPS 1545
Query: 303 FGNKIFQDGEMWSSINCTICA-----CVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
G+ + S+ C C G R +C C G + +GC C
Sbjct: 1546 PGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGS--DERGCGGPC 1603
Query: 358 TEKPGVC 364
C
Sbjct: 1604 APHHAPC 1610
Score = 30.4 bits (67), Expect = 5.7
Identities = 45/200 (22%), Positives = 62/200 (31%), Gaps = 61/200 (30%)
Query: 191 CTGGRTQCVREVCPILSCP-------QHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSD 243
C G R Q EVC L CP + + P G CP R DL C++R
Sbjct: 3291 CEGPRAQ--GEVCQALPCPVTNCTAIEGAEYSPCGPPCP-----RSCDDLVH--CVWRCQ 3341
Query: 244 VYDNGSSFLYDNCTACTCRDSTVVCKRK--CSHPGGCDQGQEGCCEECLLRVPPEDIKVC 301
C C V+ C PG C C + L
Sbjct: 3342 -------------PGCYCPPGQVLSSNGAICVQPGHCS------CLDLLT---------- 3372
Query: 302 KFGNKIFQDGEMWSSINCTICACVKGRTECRNKQC-IPISSCP-----------QGKILN 349
G + + C C C++GR C + C +P CP +G+ +
Sbjct: 3373 --GQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRS 3430
Query: 350 RKGCCPICTEKPGVCTVFGD 369
R C T + G G+
Sbjct: 3431 RSRACACPTPQHGGAPCTGE 3450
Score = 30.0 bits (66), Expect = 7.4
Identities = 30/121 (24%), Positives = 43/121 (35%), Gaps = 22/121 (18%)
Query: 259 CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSIN 318
C C + T++ C P C CE PP + GN Q+G+ +
Sbjct: 1312 CFCPEGTLLHGGACLEPASCP------CEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGD 1365
Query: 319 CTIC-----ACVKGRTECR-NKQCIP-------ISSCPQGKILNRKGC-CPICTEKPGVC 364
C AC +G C+ N C+P C G + +GC P C E C
Sbjct: 1366 GGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGS--DEEGCAAPGCGEGQMTC 1423
Query: 365 T 365
+
Sbjct: 1424 S 1424
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
Length = 1403
Score = 185 bits (469), Expect = 1e-46
Identities = 132/448 (29%), Positives = 191/448 (42%), Gaps = 43/448 (9%)
Query: 255 NCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG-EM 313
+C + + VC+ C CD G + C VP + C + G E
Sbjct: 368 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC---VPLNNGCGCWANGTYHEAGSEF 424
Query: 314 WSSINCTI-CACVKGRTECRNKQCIPISSCPQGKILN-----RKGCCPICTEKPGVCTVF 367
W+ C+ C C G C P +SC G++ + GC P+ T + C +
Sbjct: 425 WADGTCSQWCRCGPGGGSL---VCTP-ASCGLGEVCGLLPSGQHGCQPVSTAE---CQAW 477
Query: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSP---ASPFQVLVKNDARRTRSFSWTKSVELV 424
GDPHY T DG F+FQGTC+Y+L+ C P A F V V N+ R +++ S+T+SV L
Sbjct: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQ 537
Query: 425 LGESRVSLQQHLTVRW------NGSRIALPCRAPHF-HIDLDGYLLKVTTKAGLEISWDG 477
+ ++L + RW +G +ALP + H L G + VTT +GL +++DG
Sbjct: 538 IYNHSLTL----SARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
Query: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
DSFV + LCGLCGNYN DDL G W+V + C
Sbjct: 594 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 645
Query: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
KP P C + C + + + CH V A +++ C+ D C+ H
Sbjct: 646 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHP 705
Query: 596 NCYCESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
C + Y ACQ G ++ W C QC + Y+ CG C +C + +
Sbjct: 706 GGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAPEG 764
Query: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
C C GC C A VL C+ C
Sbjct: 765 CESACREGCVCDAGFVLSGDTCVPVGQC 792
Score = 157 bits (396), Expect = 4e-38
Identities = 109/364 (29%), Positives = 163/364 (44%), Gaps = 24/364 (6%)
Query: 331 CRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVL 390
C C P +C K +G C C ++GDPHY++FDGR F+FQGTC YVL
Sbjct: 47 CHGVTCRPQETC---KEQGGQGVC--LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVL 101
Query: 391 -TKDC----SSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLT--VRWNGS 443
T C + +PF V KN+ R + S+ + V + + +S+ + VR NG
Sbjct: 102 ATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGV 161
Query: 444 RIALPCRAPHFHIDLDGYLLKVTTKA--GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYN 501
ALP I + K A GL++S+D + V+V G +CGLCGN +
Sbjct: 162 LTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMD 221
Query: 502 GHKRDDLIGGDGNFKFDVDDFAESWRVES-NEFCNRPQRKPVPELCQGTVKVKLRAHREC 560
+ +D + +G + + SWR + C R P + ++ + C
Sbjct: 222 RNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE-QYEGPGFC 280
Query: 561 QKLK---SWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH 617
L F TCH+ V +F++ CV D+C + C++ +Y ACQ G+ +
Sbjct: 281 GPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIE 340
Query: 618 -WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEI---GPCNKPCVAGCHCPANLVLHK 673
W Q C T C + Y+ CGP C +C + + C PCV GC C A VL
Sbjct: 341 DWRAQVGCEIT-CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA 399
Query: 674 GRCI 677
RC+
Sbjct: 400 DRCV 403
Score = 155 bits (391), Expect = 2e-37
Identities = 125/440 (28%), Positives = 186/440 (42%), Gaps = 41/440 (9%)
Query: 261 CRDSTVVCKRKCSHPGGCDQG-QEGC-CEECLLRVPPEDIKV----CKFGNKIFQDGEM- 313
C DS V S P GC+ +EGC C+ + + V C + + GE+
Sbjct: 748 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 807
Query: 314 WSSINCTI-CACVKG-RTECRN-KQCIPISSCPQG---KILNRKGCCPICTEKPGVCTVF 367
+ C C C G C+ C P C + + GC G C
Sbjct: 808 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC--------GRCLAN 859
Query: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQ---VLVKNDARRTRSFSWTKSVELV 424
G HY T DGR ++ G+C YVL + C VL KN A + T + ++V
Sbjct: 860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVV 919
Query: 425 LGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVM 484
SL Q V +G +ALP + +G + + T GL + +DGD+ + +
Sbjct: 920 ------SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMS 973
Query: 485 AAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVE-SNEFCNR---PQRK 540
+G+LCGLCGN+NG+ DD + +G+ V+ F +WRV S++ C PQ
Sbjct: 974 IPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGC 1033
Query: 541 PVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCY 598
PV C ++ C +L++ + F TC + + + ++R CV D+C K
Sbjct: 1034 PV---CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 1090
Query: 599 CESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNK 657
C S AYT ACQ G+ V W C C + Y C C +C + + C
Sbjct: 1091 CRSLAAYTAACQAAGVAVKPWRTDSFC-PLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 1149
Query: 658 PCVAGCHCPANLVLHKGRCI 677
C GC C +L +G CI
Sbjct: 1150 RCFEGCECDDRFLLSQGVCI 1169
Score = 56.6 bits (135), Expect = 7e-08
Identities = 60/268 (22%), Positives = 96/268 (35%), Gaps = 25/268 (9%)
Query: 259 CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECL--------------LRVPPEDIKVCKFG 304
C +C R C G GC C + +P +D G
Sbjct: 1121 CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNG 1180
Query: 305 NKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVC 364
+ + + +S C+C + C + CP G++ K C G+C
Sbjct: 1181 RYLPVNSSLLTSDCSERCSC----SSSSGLTC-QAAGCPPGRVCEVKAEARNCWATRGLC 1235
Query: 365 TVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVE 422
+ + TFDG Y L+ C + P+ +V V
Sbjct: 1236 VLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH 1295
Query: 423 LVLGESRVSLQQHLTVRWNGSRIALPCR---APHFHIDLDGYLLKVTTKAGLEISWDGDS 479
+ + V+L + V NG R+ LP + DG LL V KAG+++ +
Sbjct: 1296 IFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLL-VRQKAGVQVWLGANG 1354
Query: 480 FVEVMAAPHLKGKLCGLCGNYNGHKRDD 507
V V+ + GKLCG CGN++G + +D
Sbjct: 1355 KVAVIVSNDHAGKLCGACGNFDGDQTND 1382
Score = 31.6 bits (70), Expect = 2.5
Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 22/94 (23%)
Query: 127 PCVLR-QCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEG-- 183
PCV QC G V S RCV PL + C GC G ++ G EF +G
Sbjct: 384 PCVEGCQCDAGFVL-SADRCV-----PLNN------GC-GCWANGTYHEAGSEFWADGTC 430
Query: 184 SKCTKCSCTGGRTQC------VREVCPILSCPQH 211
S+ +C GG C + EVC +L QH
Sbjct: 431 SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 464
Score = 31.6 bits (70), Expect = 2.5
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 133 CQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKC-TKCSC 191
C+EG V ++G V + +G C GC+ +G Y GE F P G +C +C C
Sbjct: 769 CREGCVCDAGF---VLSGDTCVPVGQC-----GCLHDGRYYPLGEVFYP-GPECERRCEC 819
Query: 192 -TGGRTQC 198
GG C
Sbjct: 820 GPGGHVTC 827
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 185 bits (469), Expect = 1e-46
Identities = 132/448 (29%), Positives = 191/448 (42%), Gaps = 43/448 (9%)
Query: 255 NCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG-EM 313
+C + + VC+ C CD G + C VP + C + G E
Sbjct: 1968 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC---VPLNNGCGCWANGTYHEAGSEF 2024
Query: 314 WSSINCTI-CACVKGRTECRNKQCIPISSCPQGKILN-----RKGCCPICTEKPGVCTVF 367
W+ C+ C C G C P +SC G++ + GC P+ T + C +
Sbjct: 2025 WADGTCSQWCRCGPGGGSL---VCTP-ASCGLGEVCGLLPSGQHGCQPVSTAE---CQAW 2077
Query: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSP---ASPFQVLVKNDARRTRSFSWTKSVELV 424
GDPHY T DG F+FQGTC+Y+L+ C P A F V V N+ R +++ S+T+SV L
Sbjct: 2078 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQ 2137
Query: 425 LGESRVSLQQHLTVRW------NGSRIALPCRAPHF-HIDLDGYLLKVTTKAGLEISWDG 477
+ ++L + RW +G +ALP + H L G + VTT +GL +++DG
Sbjct: 2138 IYNHSLTL----SARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2193
Query: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
DSFV + LCGLCGNYN DDL G W+V + C
Sbjct: 2194 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 2245
Query: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
KP P C + C + + + CH V A +++ C+ D C+ H
Sbjct: 2246 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHP 2305
Query: 596 NCYCESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
C + Y ACQ G ++ W C QC + Y+ CG C +C + +
Sbjct: 2306 GGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAPEG 2364
Query: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
C C GC C A VL C+ C
Sbjct: 2365 CESACREGCVCDAGFVLSGDTCVPVGQC 2392
Score = 172 bits (436), Expect = 9e-43
Identities = 141/497 (28%), Positives = 208/497 (41%), Gaps = 65/497 (13%)
Query: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR 262
CP LSCP + + G CP SC NG++ NC+ C
Sbjct: 741 CP-LSCPANSRYELCGPACPT-------------SC--------NGAA-APSNCSGRPCV 777
Query: 263 DSTVVCKRKCSHPGGCDQGQE-GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI 321
+ V + G C GC + L P + E+W+ C
Sbjct: 778 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQ---------------EVWADELCQR 822
Query: 322 CACVKGRTE---CRNKQCIPISSCPQGKILNRK----GCCPICTEKPGVCTVFGDPHYNT 374
G T CR+KQ SCP G+ + + GC P ++ G C GDPHY +
Sbjct: 823 RCTCNGATHQVTCRDKQ-----SCPAGERCSVQNGLLGCYP---DRFGTCQGSGDPHYVS 874
Query: 375 FDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSL 432
FDGR F+F GTC Y+L C A+ F+VLV+N+ R +++ S+T++V + +V++
Sbjct: 875 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAV 934
Query: 433 QQHLT--VRWNGSRIALPCRAPHFHIDL--DGYLLKVTTKAGLEISWDGDSFVEVMAAPH 488
++ V + LP +A + + G V T GL +++D ++ V
Sbjct: 935 RREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSS 994
Query: 489 LKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQG 548
LCGLCGN+NG DDL G + F SW+ E+ C + P+L
Sbjct: 995 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKL-DS 1053
Query: 549 TVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYT 606
V +L++ EC L + F+ CHS +D R CV D C P C++ Y
Sbjct: 1054 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1113
Query: 607 RACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHC 665
ACQ G VH W ++ C + C + Y+ C GC +C + G C C GC C
Sbjct: 1114 AACQAAGATVHPWRSEELCPLS-CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVC 1172
Query: 666 PANLVLHKGRCIKPVLC 682
L C+ C
Sbjct: 1173 DEGFALSGESCLPLASC 1189
Score = 165 bits (418), Expect = 1e-40
Identities = 108/363 (29%), Positives = 155/363 (42%), Gaps = 18/363 (4%)
Query: 331 CRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVL 390
C QC C +++ K C E VC GDPHY TFDGR ++ GTC Y +
Sbjct: 444 CEGMQCAAGQRC---QVVGGKAGC--VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 498
Query: 391 TKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQ----HLTVRWNGSR 444
+ CS + F V KN+ R +R S+ V + VSL + + V SR
Sbjct: 499 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 558
Query: 445 IALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHK 504
+ + + G V GL +++D D + + + ++CGLCGNYNG
Sbjct: 559 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 618
Query: 505 RDDLIGGDGNFKFDVDDFAESWRVESNEF-CNRPQRKPVPELCQGTVKVKLRAHRECQKL 563
DD + DG D +FA SW+++ ++ C + P G + R C L
Sbjct: 619 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQ-HYEGDRLCGML 677
Query: 564 KSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEP 620
+ F CH T+D F CV D+C + C AY +AC GI V W
Sbjct: 678 TKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 737
Query: 621 QQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCN-KPCVAGCHCPANLVLHKGRCIKP 679
NC + C + Y+ CGP C +C+ C+ +PCV GC C V G C+
Sbjct: 738 PANCPLS-CPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 796
Query: 680 VLC 682
C
Sbjct: 797 SSC 799
Score = 164 bits (415), Expect = 3e-40
Identities = 138/471 (29%), Positives = 202/471 (42%), Gaps = 62/471 (13%)
Query: 261 CRDSTVVCKRKCSHPGGCDQGQEGCCEECLLR----------VPPEDIKVCK-FGNKIFQ 309
C D+ C CS Q Q+GC E C VP I+ C + N ++
Sbjct: 1541 CADT---CSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVP---IQQCGCYHNGVYY 1594
Query: 310 DGEMWSSI-NCTI-CACVKGR-TECRNKQCIPISSC-PQGKILN--RKGCC--------P 355
+ E I NC C C G+ C+ C P C P G IL+ K C
Sbjct: 1595 EPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQE 1654
Query: 356 ICTEKPG----------VCTVFGDPHYNTFDGRTFNFQGTCQYVL-TKDCSSPAS----P 400
C E+ G C ++GDPHY++FDGR F+FQGTC YVL T C ++ P
Sbjct: 1655 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 1714
Query: 401 FQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQH----LTVRWNGSRIALPCRAPHFHI 456
F V KN R + S+ + V + + +S+ + + V NG ALP I
Sbjct: 1715 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRI 1774
Query: 457 DLDGYLLKVTTKA--GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGN 514
+ K A GL++S+D + V+V G +CGLCGN + + +D + +G
Sbjct: 1775 SVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 1834
Query: 515 FKFDVDDFAESWRVES-NEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWE---FQT 570
+ + SWR + C R P + ++ + C L S F T
Sbjct: 1835 LAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE-QYEGPGFCGPLASGTGGPFTT 1893
Query: 571 CHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQC 629
CH+ V +F++ CV D+C ++ C++ +Y ACQ G+ + W Q C T C
Sbjct: 1894 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT-C 1952
Query: 630 KHGAVYDTCGPGCIKTCDNWNEI---GPCNKPCVAGCHCPANLVLHKGRCI 677
+ Y+ CGP C +C + + C PCV GC C A VL RC+
Sbjct: 1953 PENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 2003
Score = 153 bits (387), Expect = 4e-37
Identities = 124/440 (28%), Positives = 185/440 (42%), Gaps = 41/440 (9%)
Query: 261 CRDSTVVCKRKCSHPGGCDQG-QEGC-CEECLLRVPPEDIKV----CKFGNKIFQDGEM- 313
C DS V S P GC+ +EGC C+ + + V C + + GE+
Sbjct: 2348 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 2407
Query: 314 WSSINCTI-CACVKG-RTECRN-KQCIPISSCPQG---KILNRKGCCPICTEKPGVCTVF 367
+ C C C G C+ C P C + + GC G C
Sbjct: 2408 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC--------GRCLAN 2459
Query: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQ---VLVKNDARRTRSFSWTKSVELV 424
G HY T DGR ++ G+C YVL + C VL KN A + T + ++V
Sbjct: 2460 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVV 2519
Query: 425 LGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVM 484
SL Q V +G +ALP + +G + + T GL + +DGD+ + +
Sbjct: 2520 ------SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMS 2573
Query: 485 AAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVE-SNEFCNR---PQRK 540
+G+LCGLCGN+NG+ DD + +G+ V+ F +WR S++ C PQ
Sbjct: 2574 IPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGC 2633
Query: 541 PVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCY 598
PV C ++ C +L++ + F TC + + + ++R CV D+C K
Sbjct: 2634 PV---CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 2690
Query: 599 CESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNK 657
C S AYT ACQ G+ V W C C + Y C C +C + + C
Sbjct: 2691 CRSLAAYTAACQAAGVAVKPWRTDSFC-PLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 2749
Query: 658 PCVAGCHCPANLVLHKGRCI 677
C GC C +L +G CI
Sbjct: 2750 RCFEGCECDDRFLLSQGVCI 2769
Score = 151 bits (381), Expect = 2e-36
Identities = 135/501 (26%), Positives = 198/501 (39%), Gaps = 64/501 (12%)
Query: 201 EVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPF-GSCLFRSDVYDNGSSFLYDNCTAC 259
E+CP LSCP H + CP G DLP G C S+ ++ C
Sbjct: 1130 ELCP-LSCPPHSHYEACSYGCPLSCG-----DLPVPGGC--GSECHEG-----------C 1170
Query: 260 TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINC 319
C + + C C GC + P + F G S+
Sbjct: 1171 VCDEGFALSGESCLPLASC-----GCVHQGTYHPP----------GQTFYPGPGCDSL-- 1213
Query: 320 TICACVKGR-TECRNKQCIPISSC-PQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDG 377
C C +G C + C P +C P G L GC + + C GDPHY TFDG
Sbjct: 1214 --CHCQEGGLVSCESSSCGPHEACQPSGGSL---GCVAVGSS---TCQASGDPHYTTFDG 1265
Query: 378 RTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQH 435
R F+F GTC YVL + C + F VL +N A S T+ + + + + L+Q
Sbjct: 1266 RRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR 1325
Query: 436 L-TVRWNGSRIALPCRAPHFHIDLD--GYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGK 492
V NG + LP + I G + + T GL +++D +V V + +
Sbjct: 1326 QWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQ 1385
Query: 493 LCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR-VESNEFCNRPQRKP------VPE- 544
+CGLCGNYNG +DD +G+ + ++F SW V + C P P +P
Sbjct: 1386 MCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSH 1445
Query: 545 LCQGTVKVKLRAHRECQKLKS--WEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESF 602
C ++ K + C L S +CH VD + C+ D+C + + C +
Sbjct: 1446 KCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNI 1505
Query: 603 LAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVA 661
AY ACQ G V W + C +C + Y+ C C C + C C
Sbjct: 1506 HAYVSACQAAGGHVEPWRTETFCPM-ECPPNSHYELCADTCSLGCSALSAPPQCQDGCAE 1564
Query: 662 GCHCPANLVLHKGRCIKPVLC 682
GC C + + + C+ C
Sbjct: 1565 GCQCDSGFLYNGQACVPIQQC 1585
Score = 56.6 bits (135), Expect = 7e-08
Identities = 60/268 (22%), Positives = 96/268 (35%), Gaps = 25/268 (9%)
Query: 259 CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECL--------------LRVPPEDIKVCKFG 304
C +C R C G GC C + +P +D G
Sbjct: 2721 CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNG 2780
Query: 305 NKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVC 364
+ + + +S C+C + C + CP G++ K C G+C
Sbjct: 2781 RYLPVNSSLLTSDCSERCSC----SSSSGLTC-QAAGCPPGRVCEVKAEARNCWATRGLC 2835
Query: 365 TVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVE 422
+ + TFDG Y L+ C + P+ +V V
Sbjct: 2836 VLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH 2895
Query: 423 LVLGESRVSLQQHLTVRWNGSRIALPCR---APHFHIDLDGYLLKVTTKAGLEISWDGDS 479
+ + V+L + V NG R+ LP + DG LL V KAG+++ +
Sbjct: 2896 IFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLL-VRQKAGVQVWLGANG 2954
Query: 480 FVEVMAAPHLKGKLCGLCGNYNGHKRDD 507
V V+ + GKLCG CGN++G + +D
Sbjct: 2955 KVAVIVSNDHAGKLCGACGNFDGDQTND 2982
Score = 34.7 bits (78), Expect = 0.30
Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 33/140 (23%)
Query: 100 ACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMC 159
AC C G N C R C EG V G + G C
Sbjct: 757 ACPTSCNGAAAPSN--------------CSGRPCVEGCVCLPGF---------VASGGAC 793
Query: 160 CPTCP-GCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPG 218
P GC F+G+Q G+E + +C+C G Q ++C S P G
Sbjct: 794 VPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQ--------VTCRDKQS-CPAG 844
Query: 219 QCCPKCLGQRKVFDLPFGSC 238
+ C G + FG+C
Sbjct: 845 ERCSVQNGLLGCYPDRFGTC 864
Score = 31.6 bits (70), Expect = 2.5
Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 22/94 (23%)
Query: 127 PCVLR-QCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEG-- 183
PCV QC G V S RCV PL + C GC G ++ G EF +G
Sbjct: 1984 PCVEGCQCDAGFVL-SADRCV-----PLNN------GC-GCWANGTYHEAGSEFWADGTC 2030
Query: 184 SKCTKCSCTGGRTQC------VREVCPILSCPQH 211
S+ +C GG C + EVC +L QH
Sbjct: 2031 SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 2064
Score = 31.6 bits (70), Expect = 2.5
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 133 CQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKC-TKCSC 191
C+EG V ++G V + +G C GC+ +G Y GE F P G +C +C C
Sbjct: 2369 CREGCVCDAGF---VLSGDTCVPVGQC-----GCLHDGRYYPLGEVFYP-GPECERRCEC 2419
Query: 192 -TGGRTQC 198
GG C
Sbjct: 2420 GPGGHVTC 2427
Score = 30.4 bits (67), Expect = 5.7
Identities = 21/73 (28%), Positives = 28/73 (38%), Gaps = 9/73 (12%)
Query: 132 QCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSC 191
+C EG V + G PL +C GCV +G + G+ F P + C C
Sbjct: 1165 ECHEGCVCDEGFALSGESCLPLA-------SC-GCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
Query: 192 -TGGRTQCVREVC 203
GG C C
Sbjct: 1217 QEGGLVSCESSSC 1229
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 182 bits (461), Expect = 1e-45
Identities = 125/438 (28%), Positives = 187/438 (42%), Gaps = 50/438 (11%)
Query: 258 ACTCRDSTV--VCKRKCSHPGGCDQGQ---EGCCEECLLRVPPEDIKVCKFGNKIFQDGE 312
A TC+ + +C+ +C C +GQ EG C E P C K + G
Sbjct: 309 ARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVEST-ECP------CVHSGKRYPPGT 361
Query: 313 MWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHY 372
S +C C C + C N++C PG C V G H+
Sbjct: 362 SLSR-DCNTCICRNSQWICSNEEC------------------------PGECLVTGQSHF 396
Query: 373 NTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTRSFSWTKSVELVLG---ES 428
+FD R F F G CQY+L +DC + F ++++ R T+SV + L S
Sbjct: 397 KSFDNRYFTFSGICQYLLARDCQDHS--FSIVIETVQCADDRDAVCTRSVTVRLPGLHNS 454
Query: 429 RVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYL-LKVTTKAGLEISWDGDSFVEVMAAP 487
V L+ V +G + LP I ++++ L++ WDG + V +P
Sbjct: 455 LVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSP 514
Query: 488 HLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQ 547
GK CGLCGNYNG++ DD + G + V+DF +W++ + C Q K + C
Sbjct: 515 VYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGD--CQDLQ-KQHSDPCA 571
Query: 548 GTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTR 607
++ + C L S F+ CH V + R+C D+C C + C C + +Y
Sbjct: 572 LNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAA 631
Query: 608 ACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWN-EIGPCNKPCVAGCHCP 666
AC G++V W C C G VY CG C TC + + CN+ C+ GC CP
Sbjct: 632 ACAGRGVRVAWREPGRC-ELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCP 690
Query: 667 ANLVL-HKGRCIKPVLCP 683
L + +G C+ CP
Sbjct: 691 PGLYMDERGDCVPKAQCP 708
Score = 160 bits (406), Expect = 3e-39
Identities = 165/662 (24%), Positives = 243/662 (36%), Gaps = 97/662 (14%)
Query: 56 VLQIPFITDNPCIMCVCLN-KEVTC---KREKCPVLSRDCALAIKQRGACCEQC-KGCTY 110
V +P++ + +C C + +E C R +A ++ G C C KG Y
Sbjct: 599 VSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVY 658
Query: 111 E--GNTYNSSFKWQS-PAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPT--CPG 165
G N + + S P E C C EG G+ ++ G C P CP
Sbjct: 659 LQCGTPCNLTCRSLSYPDEECN-EACLEGCFCPPGLY--------MDERGDCVPKAQCP- 708
Query: 166 CVFEGVQYQEGEEFQPE---GSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCP 222
C Y +GE FQPE T C C G C P P + P
Sbjct: 709 C------YYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSK 762
Query: 223 KCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQ 282
+ L R P + +D C ++ C C P G + +
Sbjct: 763 RSLSCRP----PMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHE 818
Query: 283 EGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSC 342
C L R P C K + GE I C C C + C + C
Sbjct: 819 NRCV--ALERCP------CFHQGKEYAPGET-VKIGCNTCVCRDRKWNCTDHVC------ 863
Query: 343 PQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKD-CSSPASPF 401
C+ G HY TFDG + F G CQYVL +D C S F
Sbjct: 864 ------------------DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTF 905
Query: 402 QVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGS-RIALPCR-APHFHIDLD 459
++LV N S K V +++ + L ++G + P + HF +
Sbjct: 906 RILVGNKGCSHPSVKCKKRVTILVEGGEIEL-------FDGEVNVKRPMKDETHFEVVES 958
Query: 460 GYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDV 519
G + + L + WD + V+ + K+CGLCGN++G + +DL + + D
Sbjct: 959 GRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDP 1018
Query: 520 DDFAESWRVESNEFCNRPQRKPV---PELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVD 576
DF SW+V S C ++ P+ P C + + C+ L S FQ C+ VD
Sbjct: 1019 VDFGNSWKVSSQ--CADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVD 1076
Query: 577 YATFYRSCVTDMCECPVHKN--CYCESFLAYTRACQREGIKVHWEP----QQNCAATQCK 630
+ C+ D C C + C+C++ AY C + G V W Q+C +
Sbjct: 1077 PEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLR 1136
Query: 631 HGAV-----YDTCGPGCIKTCDNWNEIGPCNKPCVAGC--HCPANLVLHK--GRCIKPVL 681
Y++C P C TC + + C CV GC HCP +L + C+ P
Sbjct: 1137 ENGYECEWRYNSCAPACQVTCQHPEPLA-CPVQCVEGCHAHCPPGKILDELLQTCVDPED 1195
Query: 682 CP 683
CP
Sbjct: 1196 CP 1197
Score = 155 bits (392), Expect = 1e-37
Identities = 96/325 (29%), Positives = 147/325 (45%), Gaps = 15/325 (4%)
Query: 364 CTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVEL 423
C++FG NTFDG ++F G C Y+L C + +N R S+ +
Sbjct: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKR--------VSLSV 86
Query: 424 VLGES-RVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKA-GLEISWDGDSFV 481
LGE + L + TV R+++P + +++ + K++ +A G DG
Sbjct: 87 YLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNF 146
Query: 482 EVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNE-FCNRPQRK 540
+V+ + K CGLCGN+N DD + +G D DFA SW + S E +C R
Sbjct: 147 QVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERAS-- 204
Query: 541 PVPELCQ-GTVKVKLRAHRECQKLKSWE-FQTCHSTVDYATFYRSCVTDMCECPVHKNCY 598
P C + +++ +CQ LKS F CH VD F C +CEC C
Sbjct: 205 PPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLECA 264
Query: 599 CESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKP 658
C + L Y R C +EG+ ++ + + C G Y C C +TC + + C +
Sbjct: 265 CPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQER 324
Query: 659 CVAGCHCPANLVLHKGRCIKPVLCP 683
CV GC CP +L +G C++ CP
Sbjct: 325 CVDGCSCPEGQLLDEGLCVESTECP 349
Score = 114 bits (285), Expect = 3e-25
Identities = 94/353 (26%), Positives = 142/353 (40%), Gaps = 31/353 (8%)
Query: 341 SCPQG----KILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSS 396
SCP K+ GC C P VCT H TFDG+ F G+C YVL + +
Sbjct: 1926 SCPNSQSPVKVEETCGCRWTC---PCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ---N 1979
Query: 397 PASPFQVLVKNDARRTRS-FSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFH 455
+V++ N A + KS+E+ V L + V NG +++P +
Sbjct: 1980 KEQDLEVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNME 2039
Query: 456 IDLDGYLLKVTTKAGL----EISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGG 511
+++ G ++ L + + F ++ K GLCG + + +D +
Sbjct: 2040 VNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLR 2099
Query: 512 DGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTC 571
DG D + W V+ RP + P + + V +H CQ L F C
Sbjct: 2100 DGTVTTDWKTLVQEWTVQ------RPGQTCQP-ILEEQCLVPDSSH--CQVLLLPLFAEC 2150
Query: 572 HSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKH 631
H + ATFY C D C H+ CE +Y C+ G+ V W CA + C
Sbjct: 2151 HKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMS-CPP 2205
Query: 632 GAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLCPQ 684
VY+ C GC + CD + C GC CP + V+ +G C+ C Q
Sbjct: 2206 SLVYNHCEHGCPRHCD--GNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQ 2256
Score = 50.1 bits (118), Expect = 7e-06
Identities = 87/361 (24%), Positives = 119/361 (32%), Gaps = 92/361 (25%)
Query: 86 VLSRDCALAIKQRGAC-----CEQCKGCTYEGNTYNSSFKWQSP---AEPC----VLRQC 133
VL+ AI Q+ +C CE + T W++P A C V C
Sbjct: 2153 VLAPATFYAICQQDSCHQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHC 2212
Query: 134 QEGV-------VTESGVRCVVHCKNPLEHL---GMCCP--TCPGCVFE-GVQYQEGEEFQ 180
+ G V+ G C P + + G C P C C+ E GVQ+Q E +
Sbjct: 2213 EHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWV 2272
Query: 181 PEGSKCTKCSCTGGR-TQCVREVCPILSCPQ-HLSHIP-----PGQCCP--KCLGQRKVF 231
P+ C C+C GR C + CP P L + QCCP +C+
Sbjct: 2273 PDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSC 2332
Query: 232 DL---------------------PFGSCLFRSDVYDNGS----------SFLYDNC---- 256
DL P +C R + S + C
Sbjct: 2333 DLPPVPHCERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQCCDEY 2392
Query: 257 -TACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWS 315
AC C +STV C + GC L P+ KVC + I+ G+ W
Sbjct: 2393 ECACNCVNSTVSC--PLGYLASTATNDCGCTTTTCL---PD--KVCVHRSTIYPVGQFWE 2445
Query: 316 SINCTICACVKGR--------TECRNKQCIPISSCPQG--KILNRKGCCPICTEKPGVCT 365
C +C C +C K C SC G +L+ CC C P C
Sbjct: 2446 E-GCDVCTCTDMEDAVMGLRVAQCSQKPC--EDSCRSGFTYVLHEGECCGRCL--PSACE 2500
Query: 366 V 366
V
Sbjct: 2501 V 2501
Score = 48.5 bits (114), Expect = 2e-05
Identities = 75/346 (21%), Positives = 107/346 (30%), Gaps = 76/346 (21%)
Query: 70 CVCLNKEVTCKREK-CPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPC 128
C C+N V+C + DC C K C + Y W+ + C
Sbjct: 2396 CNCVNSTVSCPLGYLASTATNDCGCTT----TTCLPDKVCVHRSTIYPVGQFWEEGCDVC 2451
Query: 129 VLRQCQEGVVTESGVRCVVHCKNPLE-----------HLGMCCPTCPGCVFEGVQYQEGE 177
++ V+ G+R + P E H G CC C E V
Sbjct: 2452 TCTDMEDAVM---GLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGS--- 2505
Query: 178 EFQPEGSKCTKCSCTGGR----------TQCVREVCPI------LSCPQHLSHIPPG--- 218
P G + G + +CVR + +SCPQ + P
Sbjct: 2506 ---PRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQ 2562
Query: 219 ------QCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVV----- 267
CCP C +R +C+ V G + + D CT C C V
Sbjct: 2563 LSCKTSACCPSCRCER------MEACMLNGTVIGPGKTVMIDVCTTCRCMVQVGVISGFK 2616
Query: 268 --CKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIF---QDGEMWSSINCTIC 322
C++ +P +E EC R P + G +I +D + + C
Sbjct: 2617 LECRKTTCNPCPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFC 2676
Query: 323 ACVKGRTEC----RNKQCIPISS----CPQGKILNRKG-CCPICTE 359
V R E R C P GKI+ G CC C E
Sbjct: 2677 K-VNERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCEE 2721
Score = 31.6 bits (70), Expect = 2.5
Identities = 43/203 (21%), Positives = 64/203 (31%), Gaps = 54/203 (26%)
Query: 50 CENEGEVLQIPFITDNPCIMCVCLNKEVTCKREKCP-VLSRDCALA--IKQRGACCEQCK 106
C +GE+ Q I + MC C + + C P L D L+ + R C+
Sbjct: 709 CYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCR 768
Query: 107 GCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKN-PLEHLGMCCPT--- 162
P V C + G+ C C+N LE + M C +
Sbjct: 769 -------------------PPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCL 809
Query: 163 CP----------------GCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPIL 206
CP C +G +Y GE + C C C + C VC
Sbjct: 810 CPPGMVRHENRCVALERCPCFHQGKEYAPGETVK---IGCNTCVCRDRKWNCTDHVCDAT 866
Query: 207 SCPQHLSH---------IPPGQC 220
++H + PG+C
Sbjct: 867 CSTIGMAHYLTFDGLKYLFPGEC 889
Score = 30.4 bits (67), Expect = 5.7
Identities = 31/126 (24%), Positives = 41/126 (32%), Gaps = 34/126 (26%)
Query: 159 CCPTCPGCVFEGVQYQEGEEFQPEGSKCTK-CSCTGGRTQCVREVCPILSCPQHLSHIPP 217
C P CP G E++ S C + C C SCP+ +
Sbjct: 291 CSPVCPA----------GMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEG-QLLDE 339
Query: 218 GQC-----CPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKC 272
G C CP C+ Y G+S D C C CR+S +C +
Sbjct: 340 GLCVESTECP---------------CVHSGKRYPPGTSLSRD-CNTCICRNSQWICSNE- 382
Query: 273 SHPGGC 278
PG C
Sbjct: 383 ECPGEC 388
Score = 30.4 bits (67), Expect = 5.7
Identities = 42/153 (27%), Positives = 54/153 (35%), Gaps = 32/153 (20%)
Query: 268 CKRKCS-HPGGC-DQGQEGCC---EECLLR---VPPEDIKVCKFGNKIFQDG------EM 313
C R C + C D EGC ++ +L VP E C I +DG E
Sbjct: 2216 CPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQC-----IGEDGVQHQFLEA 2270
Query: 314 WSSIN--CTICACVKGR-TECRNKQCIPISSCPQGKIL-------NRKGCCP--ICTEKP 361
W + C IC C+ GR C + C P + P + N CCP C P
Sbjct: 2271 WVPDHQPCQICTCLSGRKVNCTTQPC-PTAKAPTCGLCEVARLRQNADQCCPEYECVCDP 2329
Query: 362 GVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDC 394
C + PH T G C+ T C
Sbjct: 2330 VSCDLPPVPHCERGLQPTLTNPGECRPNFTCAC 2362
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 180 bits (457), Expect = 3e-45
Identities = 119/395 (30%), Positives = 170/395 (43%), Gaps = 27/395 (6%)
Query: 301 CKFGNKIFQDGEM-WSSINCTI-CACVKGRTE--CRNKQCIPISSC-PQGKILNRKGCCP 355
C + + GE+ W +NCT+ C C+ E C+ C P C P+GK C
Sbjct: 260 CTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFY---CSA 316
Query: 356 ICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASP--FQVLVKNDARRTR 413
+ T C VFG+PHY+TFDG F+FQG+C Y+L + C +S F V KN+ RR
Sbjct: 317 VETS---TCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGS 373
Query: 414 SFSWTKSVELVLGESRVSLQQ--HLTVRWNGSRIALPCRAPHFHIDL--DGYLLKVTTKA 469
+ SW K + + + ++ + + + V+ N +LP + + G V T
Sbjct: 374 AVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDF 433
Query: 470 GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVE 529
GL +++DG + + CGLCGNYN + DD + DG V D ESWRV
Sbjct: 434 GLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVY 493
Query: 530 SNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKS-----WEFQTCHSTVDYATFYRSC 584
++ C + C L WE C + VD F SC
Sbjct: 494 HADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWE---CGTVVDPTAFVHSC 550
Query: 585 VTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEPQQNCAAT-QCKHGAVYDTCGPGC 642
V D+C + C++ AY CQ GI + W Q C +T QC + Y C C
Sbjct: 551 VYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSC 610
Query: 643 IKTCDNWNEIGPCNKPCVAGCHCPANLVLHKGRCI 677
TC + C PC GC C VL +C+
Sbjct: 611 PDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCV 645
Score = 163 bits (412), Expect = 6e-40
Identities = 130/452 (28%), Positives = 194/452 (42%), Gaps = 38/452 (8%)
Query: 253 YDNCTACT--CRDSTV--VCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKF-GNKI 307
++ C CT C T+ +C CS CD+G +C+ R C F G+++
Sbjct: 990 FEECITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECG----CNFEGHQL 1045
Query: 308 FQDGEMWSSINCTI---CACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGV- 363
+ W ++C I C+ R C C C + +G C +
Sbjct: 1046 ATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCME------EGGLYYCQARTDAS 1099
Query: 364 CTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASP----FQVLVKNDARRTRSFSWTK 419
C V G HY TFDG F+FQ +C +L S P+S F V KN+ R W K
Sbjct: 1100 CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVK 1159
Query: 420 SVEL-VLGESRVSLQQHL-TVRWNGSRIALPCRAPHFHIDLD--GYLLKVTTKAGLEISW 475
V++ V G S V + + TV N R+ LP + I++ G+ + V T GL++ +
Sbjct: 1160 QVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVY 1219
Query: 476 DGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535
D +F+ + ++ GLCG YNG+ DDL G V++F +SW V+ + FC
Sbjct: 1220 DWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW-VKRDTFC- 1277
Query: 536 RPQRKPVPELCQGTVKVK--LRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCEC 591
+ + C KV+ + + C + + F CHS V+ FY++C+ D C
Sbjct: 1278 ---QVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCID 1334
Query: 592 PVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWN 650
C Y CQ +GI V W +C T C + Y++C C C
Sbjct: 1335 GGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVT-CPPNSHYESCVSVCQPRCAAIR 1393
Query: 651 EIGPCNKPCVAGCHCPANLVLHKGRCIKPVLC 682
C+ CV GCHC A VL+ CI P C
Sbjct: 1394 LKSDCSHYCVEGCHCDAGYVLNGKSCILPHSC 1425
Score = 132 bits (331), Expect = 1e-30
Identities = 114/431 (26%), Positives = 184/431 (42%), Gaps = 44/431 (10%)
Query: 253 YDNCTA-CTCRDSTVVCKRKCSH----PGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKI 307
Y++C + C R + + K CSH CD G + C+L P C K
Sbjct: 1378 YESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCIL---PHSCG-CYSDGKY 1433
Query: 308 FQDGEMWSSINCTI-CACVKGRT-ECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCT 365
++ +++ + +CT C C + +C +QC C R G + K C
Sbjct: 1434 YEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECAL-----RNGVRGCFSTKTSYCL 1488
Query: 366 VFGDPHYNTFDGRTFNFQGTCQYVLTKDCSS-PASPFQVLVKNDARRTRSFSWTKSVELV 424
G + TFDG F C +VL+ C P FQ+++ D + + V
Sbjct: 1489 AAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFY 1548
Query: 425 LGESRVSLQQHLTVRWNGSRIALPC---RAPHFHIDLDGYLLKVTTKAGLEISWDGDSFV 481
+ E ++ + TV+ NG+++ +P A + +G+L+ + T ++I ++G + +
Sbjct: 1549 INEEQILINDRNTVKVNGTQVNVPFITGLATKIYSS-EGFLV-IDTSPDIQIYYNGFNVI 1606
Query: 482 EVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNE------FCN 535
++ + L+ K+CGLCGN+NG DD + G A+SW+ + CN
Sbjct: 1607 KISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCN 1666
Query: 536 RPQRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPV 593
Q +C K++ C KL + FQ C+ +D FY SC D C
Sbjct: 1667 ELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYS-- 1724
Query: 594 HKNC-YCESFLAYTRACQREGI-KVHWEPQQNCAATQCKHGAVYDTC-GPGC-IKTCD-- 647
HK C S AY AC+ GI W ++NC+ G V D C G C +TC+
Sbjct: 1725 HKKFQLCGSLAAYGEACRSFGILSTEWIEKENCS------GVVEDPCVGADCPNRTCELG 1778
Query: 648 NWNEIGPCNKP 658
N E+ C +P
Sbjct: 1779 NGRELCGCIEP 1789
Score = 113 bits (283), Expect = 5e-25
Identities = 104/448 (23%), Positives = 180/448 (40%), Gaps = 32/448 (7%)
Query: 253 YDNCTAC---TCRDSTVV--CKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKI 307
Y CT+ TC D T C C+ C+QG +C+ P C F
Sbjct: 603 YSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCV----PLHKCGCDFDGHY 658
Query: 308 FQDGEM-WSSINCTI-CACVKGR-TECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVC 364
+ GE W++ NCT+ C C +G C NK C C +GC P ++ VC
Sbjct: 659 YTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVED--GYQGCFP---KRETVC 713
Query: 365 TVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELV 424
+ + +TFDG ++ F Y L K C ++ + N + +W + + ++
Sbjct: 714 LLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDI-NKKKPDAGPAWLRGLRIL 772
Query: 425 LGESRVSLQQ--HLTVRWNGSRIALPCRAPHFHIDL--DGYLLKVTTKAGLEISWDGDSF 480
+ + V + V+ NG + LP P +++ + V +K + + +
Sbjct: 773 VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGL 832
Query: 481 VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRK 540
+ + + GLCG YN + D+ +G ++ F ESW E CN
Sbjct: 833 LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTT-FEEICNGECGD 891
Query: 541 PVPELCQGTVKVKL-RAHRECQKLK---SWEFQTCHSTVDYATFYRSCVTDMCECPVHKN 596
+ + +K R+ C + + F CH V+ +YR+C+ +C+ +++
Sbjct: 892 LLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNES 951
Query: 597 CYCESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP- 654
C+S Y AC+ ++V W C +C + ++ C C +TC+ +GP
Sbjct: 952 ELCDSVARYASACKNADVEVGPWRTYDFC-PLECPENSHFEEC-ITCTETCETLT-LGPI 1008
Query: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
C C GC C L +C+ C
Sbjct: 1009 CVDSCSEGCQCDEGYALLGSQCVTRSEC 1036
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 172 bits (436), Expect = 9e-43
Identities = 141/497 (28%), Positives = 208/497 (41%), Gaps = 65/497 (13%)
Query: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR 262
CP LSCP + + G CP SC NG++ NC+ C
Sbjct: 802 CP-LSCPANSRYELCGPACPT-------------SC--------NGAA-APSNCSGRPCV 838
Query: 263 DSTVVCKRKCSHPGGCDQGQE-GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI 321
+ V + G C GC + L P + E+W+ C
Sbjct: 839 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQ---------------EVWADELCQR 883
Query: 322 CACVKGRTE---CRNKQCIPISSCPQGKILNRK----GCCPICTEKPGVCTVFGDPHYNT 374
G T CR+KQ SCP G+ + + GC P ++ G C GDPHY +
Sbjct: 884 RCTCNGATHQVTCRDKQ-----SCPAGERCSVQNGLLGCYP---DRFGTCQGSGDPHYVS 935
Query: 375 FDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSL 432
FDGR F+F GTC Y+L C A+ F+VLV+N+ R +++ S+T++V + +V++
Sbjct: 936 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAV 995
Query: 433 QQHLT--VRWNGSRIALPCRAPHFHIDL--DGYLLKVTTKAGLEISWDGDSFVEVMAAPH 488
++ V + LP +A + + G V T GL +++D ++ V
Sbjct: 996 RREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSS 1055
Query: 489 LKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQG 548
LCGLCGN+NG DDL G + F SW+ E+ C + P+L
Sbjct: 1056 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKL-DS 1114
Query: 549 TVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYT 606
V +L++ EC L + F+ CHS +D R CV D C P C++ Y
Sbjct: 1115 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1174
Query: 607 RACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHC 665
ACQ G VH W ++ C + C + Y+ C GC +C + G C C GC C
Sbjct: 1175 AACQAAGATVHPWRSEELCPLS-CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVC 1233
Query: 666 PANLVLHKGRCIKPVLC 682
L C+ C
Sbjct: 1234 DEGFALSGESCLPLASC 1250
Score = 165 bits (418), Expect = 1e-40
Identities = 108/363 (29%), Positives = 155/363 (42%), Gaps = 18/363 (4%)
Query: 331 CRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVL 390
C QC C +++ K C E VC GDPHY TFDGR ++ GTC Y +
Sbjct: 505 CEGMQCAAGQRC---QVVGGKAGC--VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 559
Query: 391 TKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQ----HLTVRWNGSR 444
+ CS + F V KN+ R +R S+ V + VSL + + V SR
Sbjct: 560 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 619
Query: 445 IALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHK 504
+ + + G V GL +++D D + + + ++CGLCGNYNG
Sbjct: 620 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 679
Query: 505 RDDLIGGDGNFKFDVDDFAESWRVESNEF-CNRPQRKPVPELCQGTVKVKLRAHRECQKL 563
DD + DG D +FA SW+++ ++ C + P G + R C L
Sbjct: 680 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQ-HYEGDRLCGML 738
Query: 564 KSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEP 620
+ F CH T+D F CV D+C + C AY +AC GI V W
Sbjct: 739 TKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 798
Query: 621 QQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCN-KPCVAGCHCPANLVLHKGRCIKP 679
NC + C + Y+ CGP C +C+ C+ +PCV GC C V G C+
Sbjct: 799 PANCPLS-CPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 857
Query: 680 VLC 682
C
Sbjct: 858 SSC 860
Score = 74.3 bits (181), Expect = 3e-13
Identities = 72/252 (28%), Positives = 100/252 (39%), Gaps = 52/252 (20%)
Query: 201 EVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPF-GSCLFRSDVYDNGSSFLYDNCTAC 259
E+CP LSCP H + CP G DLP G C S+ ++ C
Sbjct: 1191 ELCP-LSCPPHSHYEACSYGCPLSCG-----DLPVPGGC--GSECHEG-----------C 1231
Query: 260 TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINC 319
C + + C C GC + P + F G S+
Sbjct: 1232 VCDEGFALSGESCLPLASC-----GCVHQGTYHPP----------GQTFYPGPGCDSL-- 1274
Query: 320 TICACVKGR-TECRNKQCIPISSC-PQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDG 377
C C +G C + C P +C P G L GC + + C GDPHY TFDG
Sbjct: 1275 --CHCQEGGLVSCESSSCGPHEACQPSGGSL---GCVAVGSS---TCQASGDPHYTTFDG 1326
Query: 378 RTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQH 435
R F+F GTC YVL + C + F VL +N A S T+ + + + + L+Q
Sbjct: 1327 RRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR 1386
Query: 436 ---LTVRWNGSR 444
+TVR +G +
Sbjct: 1387 QWKVTVRADGEQ 1398
Score = 34.7 bits (78), Expect = 0.30
Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 33/140 (23%)
Query: 100 ACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMC 159
AC C G N C R C EG V G + G C
Sbjct: 818 ACPTSCNGAAAPSN--------------CSGRPCVEGCVCLPGF---------VASGGAC 854
Query: 160 CPTCP-GCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPG 218
P GC F+G+Q G+E + +C+C G Q ++C S P G
Sbjct: 855 VPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQ--------VTCRDKQS-CPAG 905
Query: 219 QCCPKCLGQRKVFDLPFGSC 238
+ C G + FG+C
Sbjct: 906 ERCSVQNGLLGCYPDRFGTC 925
Score = 30.4 bits (67), Expect = 5.7
Identities = 21/73 (28%), Positives = 28/73 (38%), Gaps = 9/73 (12%)
Query: 132 QCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSC 191
+C EG V + G PL +C GCV +G + G+ F P + C C
Sbjct: 1226 ECHEGCVCDEGFALSGESCLPLA-------SC-GCVHQGTYHPPGQTFYPGPGCDSLCHC 1277
Query: 192 -TGGRTQCVREVC 203
GG C C
Sbjct: 1278 QEGGLVSCESSSC 1290
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 166 bits (419), Expect = 9e-41
Identities = 150/586 (25%), Positives = 226/586 (38%), Gaps = 110/586 (18%)
Query: 100 ACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMC 159
AC C+G + T + SF P + C C G L G C
Sbjct: 710 ACQPTCRGLSEADVTCSVSFV---PVDGCT---CPAGTF--------------LNDAGAC 749
Query: 160 CPT--CPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCV-REVCPILSCPQHLSHIP 216
P CP C G GE EG+ C SCTGG+ C+ + C + ++
Sbjct: 750 VPAQECP-CYAHGTVLAPGEVVHDEGAVC---SCTGGKLSCLGASLQKSTGCAAPMVYL- 804
Query: 217 PGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPG 276
C G P CL D G F + C C PG
Sbjct: 805 --DCSNSSAGT------PGAECLRSCHTLDVGC-FSTHCVSGCVCP------------PG 843
Query: 277 GCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQC 336
G GC E ED C ++ GE ++C C C R EC ++ C
Sbjct: 844 LVSDGSGGCIAE-------EDCP-CVHNEATYKPGET-IRVDCNTCTCRNRRWECSHRLC 894
Query: 337 IPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDC-- 394
+ G C +GD H+ TFDG ++F+G+C+Y+L +D
Sbjct: 895 L------------------------GTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCG 930
Query: 395 -SSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIAL---PCR 450
++ F+++ +N T + +K+++L + + LQ+ G+ A+ P
Sbjct: 931 DNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQE-------GTFKAVARGPGG 983
Query: 451 APHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIG 510
P + I G L + T G+ +SWD + V + KG++CGLCGN++ + +D
Sbjct: 984 DPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFAT 1042
Query: 511 GDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQT 570
+ D +F SW++ + C P + C K A ++C L F
Sbjct: 1043 RSRSVVGDALEFGNSWKLSPS--C--PDALAPKDPCTANPFRKSWAQKQCSILHGPTFAA 1098
Query: 571 CHSTVDYATFYRSCVTDMCECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC---A 625
C S VD +Y +CV D C C + C+C + AY +AC G+ V W C
Sbjct: 1099 CRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFC 1158
Query: 626 ATQCKHGAV---YDTCGPGCIKTCDNWNEIGPCNKPCVAGCH--CP 666
HG Y CG C+KTC N + + P + GC+ CP
Sbjct: 1159 DFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCP 1204
Score = 142 bits (359), Expect = 8e-34
Identities = 139/532 (26%), Positives = 222/532 (41%), Gaps = 67/532 (12%)
Query: 204 PILSCPQHLSHIPPGQCCPK-CLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR 262
P CP L +P G C + + R + F C D ++ D C TC
Sbjct: 240 PTEQCPDPLP-LPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP 298
Query: 263 DSTVV-CKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIF------QDGEMWS 315
+T V R+C+H GG Q + C E R P +++ + G+ Q ++
Sbjct: 299 CATFVEYSRQCAHAGG--QPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCE 356
Query: 316 SINCTICACVKGRT-----ECRNKQCIPISSCP---------QGKILNRKGCCPICTEK- 360
C C GR+ + + C+P+ CP G N C CT
Sbjct: 357 DHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTT--CSSCTCSG 414
Query: 361 ----------PGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVK-NDA 409
PG C+V G H +T+D + ++ G C YVL+K C+ S F VL +
Sbjct: 415 GLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCAD--SSFTVLAELRKC 472
Query: 410 RRTRSFSWTKSVELVL--GESRVSLQQHLTVRWNGSRIALPCRAPHFHIDL-DGYLLKVT 466
T + + K+V L L G++ + +Q V N LP A + + + + V
Sbjct: 473 GLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQ 532
Query: 467 TKAGLEISWDGDSFVEVMAA--PHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAE 524
T GL++ ++V P +G++CGLCGN+N ++ DD G + FA
Sbjct: 533 TGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFAN 592
Query: 525 SWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLK--SWEFQTCHSTVDYATFYR 582
+W+ ++ C R + C +V+ + A C +L + F CHS ++ F+
Sbjct: 593 TWKAQAA--CANA-RNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHS 649
Query: 583 SCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEP------QQNCAATQCKHGAVY 635
+C+ D C C ++C C + +Y AC +G+++ W QNC +Q ++ V
Sbjct: 650 NCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQ-RYAYVV 708
Query: 636 DTCGPGCIKTCDNWNEIG-PCNKPCVA--GCHCPANLVLH-KGRCIKPVLCP 683
D C P TC +E C+ V GC CPA L+ G C+ CP
Sbjct: 709 DACQP----TCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECP 756
Score = 125 bits (315), Expect = 1e-28
Identities = 93/337 (27%), Positives = 138/337 (40%), Gaps = 39/337 (11%)
Query: 363 VCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN---DARRTRSFSWTK 419
VC+ +GD HY TFDG F F G C YV ++ C + F V ++ +R + K
Sbjct: 76 VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRPVVTRVVIK 135
Query: 420 SVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDS 479
+ LVL S S V NG R LP ++ G +KV+ + L W+G+
Sbjct: 136 AQGLVLEASNGS------VLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGED 189
Query: 480 FVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQR 539
+ P + CGLCG++NG + + +A + R+ +F N +
Sbjct: 190 SALLELDPKYANQTCGLCGDFNGLPAFN------------EFYAHNARLTPLQFGNLQKL 237
Query: 540 KPVPELCQGTVKVKLRAHRE----CQK-LKSWEFQTCHSTVDYATFYRSCVTDMCECPVH 594
E C + + + C + L F CH+ VD + +C D+C CP
Sbjct: 238 DGPTEQCPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCP-- 295
Query: 595 KNCYCESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIG 653
C C +F+ Y+R C G + +W + C T C + CG C TC N
Sbjct: 296 -TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRT-CPLNMQHQECGSPCTDTCSNPQRAQ 353
Query: 654 PCNKPCVAGCHCPANL-------VLHKGRCIKPVLCP 683
C CV GC CP + H G C+ CP
Sbjct: 354 LCEDHCVDGCFCPPGRSCTVLDDITHSG-CLPLGQCP 389
Score = 111 bits (278), Expect = 2e-24
Identities = 101/425 (23%), Positives = 168/425 (39%), Gaps = 48/425 (11%)
Query: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVK------------GRTECRNKQCIPISSC 342
P C + Q E W+ NCT+ CV C NK +PI
Sbjct: 5004 PSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPVANVTCVNKH-LPI--- 5059
Query: 343 PQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQ 402
K+ + C E +C+++G HY+TFDG ++ F+G C YVL ++ +
Sbjct: 5060 ---KVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLS 5116
Query: 403 VLVKND----------ARRTRSFS-WTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRA 451
+ + N AR R+ S KS+++VL + V ++ + ++ ++
Sbjct: 5117 LYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSK 5176
Query: 452 PHFHIDLDG-YLLKVTTKA-GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLI 509
+ + G ++V A G+ ++++G F + G CG ++RDD +
Sbjct: 5177 NGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCL 5236
Query: 510 GGDGNFKFDVDDFAESWRVESN--EFC-----NRPQRKPVPELCQGTVKVKLRAHRECQK 562
DG D A++W V + + C P P + C
Sbjct: 5237 QRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDL 5296
Query: 563 LKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQ 622
+ S F CH+ V F+ +C++D C + C+S AY C+ G+ W
Sbjct: 5297 MLSQVFAECHNLVPPGPFFNACISDHCRGRL--EVPCQSLEAYAELCRARGVCSDWRGAT 5354
Query: 623 N--CAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVL---HKGRCI 677
C T C VY CGP TC++ N+ P + GC CP + +L H G C+
Sbjct: 5355 GGLCDLT-CPPTKVYKPCGPIQPATCNSRNQ-SPQLEGMAEGCFCPEDQILFNAHMGICV 5412
Query: 678 KPVLC 682
+ C
Sbjct: 5413 QACPC 5417
Score = 57.8 bits (138), Expect = 3e-08
Identities = 84/310 (27%), Positives = 107/310 (34%), Gaps = 82/310 (26%)
Query: 84 CPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGV 143
CP D L G C + C +G +W S + CV C EG V+
Sbjct: 5397 CP---EDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCV---CDEGSVS---- 5446
Query: 144 RCVVHCKN-PLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREV 202
V CK P + G P C F V E C + C V
Sbjct: 5447 ---VQCKPLPCDAQGQP-PPCNRPGFVTVTRPRAEN-----PCCPETVC----------V 5487
Query: 203 CPILSCPQHLSHIPPGQ----------CCP--KCLGQRKVFDLPFGSCLFRSDVYDNGSS 250
C +CPQ L PPGQ CCP +C Q C + Y G++
Sbjct: 5488 CNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQ---------LCSYNGTFYGVGAT 5538
Query: 251 FLYD-NCTACTC-----RDSTVVCKRKCSHPGGCDQGQE------GCCEECLLR--VPPE 296
F C CTC +D TV C+ + C QG E CC EC+ + P+
Sbjct: 5539 FPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPD 5598
Query: 297 DIKVCKFGNKIFQDGEMWSSI---NCTICAC-VKGRTECRNKQ---CIPISSCPQGKILN 349
V Q E W + NCT+ C +G Q C +SSC L
Sbjct: 5599 GQPV--------QLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGS--LR 5648
Query: 350 RKGCCPICTE 359
+ GCC C E
Sbjct: 5649 KTGCCYSCEE 5658
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 32/173 (18%)
Query: 62 ITDNPCIMCVCLNKEVTCKREKCPVL---SRDCALAIKQ--RGACCEQCKGCTYEGNTYN 116
+ D+ + C C C SR CA A Q C E C T
Sbjct: 277 LVDSTAYLAACAQDLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCP------RTCP 330
Query: 117 SSFKWQSPAEPCVLR------------QCQEGVVTESGVRCVVHCKNPLEHLGMCCPT-- 162
+ + Q PC C +G G C V + + H G C P
Sbjct: 331 LNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTV--LDDITHSG-CLPLGQ 387
Query: 163 CPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHI 215
CP C G Y G F + C+ C+C+GG QC CP Q +HI
Sbjct: 388 CP-CTHGGRTYSPGTSFN---TTCSSCTCSGGLWQCQDLPCPGTCSVQGGAHI 436
Score = 34.3 bits (77), Expect = 0.39
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 10/67 (14%)
Query: 626 ATQCKHGAVYDTC--------GPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLH-KGRC 676
+T C VY C G C+++C ++G + CV+GC CP LV G C
Sbjct: 794 STGCAAPMVYLDCSNSSAGTPGAECLRSCHTL-DVGCFSTHCVSGCVCPPGLVSDGSGGC 852
Query: 677 IKPVLCP 683
I CP
Sbjct: 853 IAEEDCP 859
Score = 32.7 bits (73), Expect = 1.1
Identities = 21/85 (24%), Positives = 27/85 (31%), Gaps = 24/85 (28%)
Query: 142 GVRCVVHCKNPLEH-------LGMCCPTCP-----------------GCVFEGVQYQEGE 177
G C+ C+NP H L C P CP GC + Y +
Sbjct: 1175 GAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVG 1234
Query: 178 EFQPEGSKCTKCSCTGGRTQCVREV 202
P C C+CT QC +
Sbjct: 1235 ARVPTAENCQSCNCTPSGIQCAHSL 1259
Score = 32.3 bits (72), Expect = 1.5
Identities = 40/166 (24%), Positives = 56/166 (33%), Gaps = 43/166 (25%)
Query: 126 EPCVLRQCQEGVVTESGVRCVVHCK------NPLEHLGMCCP-----TCP-GCVFEGVQY 173
E CV C +SG C C G+C TCP C F
Sbjct: 1110 EACVNDAC----ACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHG 1165
Query: 174 QEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQ--CCPKCLGQRKVF 231
+QP G+ C K +C C+ ++ PG C PKC + F
Sbjct: 1166 GCEWHYQPCGAPCLK-TCRNPSGHCLVDL--------------PGLEGCYPKCPPSQPFF 1210
Query: 232 DLPFGSCLFRSDVYDNGSSFLYD---------NCTACTCRDSTVVC 268
+ C+ + YD ++ YD NC +C C S + C
Sbjct: 1211 NEDQMKCVAQCGCYDKDGNY-YDVGARVPTAENCQSCNCTPSGIQC 1255
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 162 bits (410), Expect = 1e-39
Identities = 139/564 (24%), Positives = 215/564 (38%), Gaps = 99/564 (17%)
Query: 133 CQEGVVTESGVRCVVHCKNPLEHLGMCCPTCP-GCVFEGVQYQEGEEFQPEGSKCTKCSC 191
C EG G C H L+ G C P C G+ + G+ + +C C
Sbjct: 688 CLEGFAPVDGCGCPDHTF--LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCV---C 742
Query: 192 TGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSF 251
GR C + SC H+ + + SC + + +
Sbjct: 743 RDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRAL-----SCQTLA------AGY 791
Query: 252 LYDNCTA-CTCRDSTVVCKRKCSHPGGCDQGQEGCC--EECLLRVPPEDIKVCKFGNKIF 308
+ C + C C D G D G+ GC +EC C N ++
Sbjct: 792 YHTECVSGCVCPD------------GLMDDGRGGCVVEKEC----------PCVHNNDLY 829
Query: 309 QDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFG 368
G ++C C C +GR C C G C+++G
Sbjct: 830 SSGAK-IKVDCNTCTCKRGRWVCTQAVC------------------------HGTCSIYG 864
Query: 369 DPHYNTFDGRTFNFQGTCQYVLTKDC---SSPASPFQVLVKNDARRTRSFSWTKSVELVL 425
HY TFDG+ ++F G C YV +D +S F ++ +N T + +K++++ +
Sbjct: 865 SGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFM 924
Query: 426 GESRVSLQ-QHLTV--RWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVE 482
G + + L+ +H V R G +A R G L V + G+ + WD + V
Sbjct: 925 GRTELKLEDKHRVVIQRDEGHHVAYTTREV-------GQYLVVESSTGIIVIWDKRTTVF 977
Query: 483 VMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPV 542
+ AP KG +CGLCGN++ +D D DF SW+ E P
Sbjct: 978 IKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----EAPTCPDVSTN 1033
Query: 543 PELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKN--CYCE 600
PE C + A ++C LKS F CHS VD FY +CV D C C + C+C
Sbjct: 1034 PEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCS 1093
Query: 601 SFLAYTRACQREGIKVHWEPQQNC--------AATQCKHGAVYDTCGPGCIKTCDNWNEI 652
+ +Y + C +EG V W C +C+ Y+ CG +TC N I
Sbjct: 1094 AVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWH--YEPCGNRSFETCRTINGI 1151
Query: 653 -GPCNKPCVAGCH--CPANLVLHK 673
+ + GC+ CP + +++
Sbjct: 1152 HSNISVSYLEGCYPRCPKDRPIYE 1175
Score = 141 bits (355), Expect = 2e-33
Identities = 88/312 (28%), Positives = 137/312 (43%), Gaps = 15/312 (4%)
Query: 363 VCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVE 422
VC+ +G+ HY TFDG F F G C Y DC F V +K + + + +S+
Sbjct: 36 VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESIL 95
Query: 423 LVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVE 482
L + + + L +HL V NG+ ++ P +P I+ KV ++AGL + W+ + +
Sbjct: 96 LTIKDDTIYLTRHLAV-LNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALM 154
Query: 483 VMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV-ESNEFCNRPQRKP 541
+ + CGLCG+YNG + DG F +F ++ + + C P+ +
Sbjct: 155 LELDTKFRNHTCGLCGDYNGLQSYSEFLSDG-VLFSPLEFGNMQKINQPDVVCEDPEEEV 213
Query: 542 VPELCQGTVKVKLRAHR-ECQKLKSWE-FQTCHSTVDYATFYRSCVTDMCECPVHKNCYC 599
P C HR EC++L + E F C V + R+C D C CP C C
Sbjct: 214 APASCS--------EHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVC 265
Query: 600 ESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKP 658
+ ++R C G + +W C T C VY G C+ TC + C +
Sbjct: 266 STVAEFSRQCSHAGGRPGNWRTATLCPKT-CPGNLVYLESGSPCMDTCSHLEVSSLCEEH 324
Query: 659 CVAGCHCPANLV 670
+ GC CP V
Sbjct: 325 RMDGCFCPEGTV 336
Score = 122 bits (306), Expect = 1e-27
Identities = 126/517 (24%), Positives = 199/517 (38%), Gaps = 74/517 (14%)
Query: 188 KCSCTGGRTQCVREVCPILSCPQHLSHIP----PGQCCPKCLGQRKVFDLPFGSCLFRSD 243
+C C GG T V H P CPK V+ C+
Sbjct: 254 RCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCS 313
Query: 244 VYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKF 303
+ S C C + TV D G GC VP C+
Sbjct: 314 HLEVSSLCEEHRMDGCFCPEGTVYD----------DIGDSGC-------VPVSQCH-CRL 355
Query: 304 GNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGV 363
++ G+ ++ +C C C GR C++ C PG
Sbjct: 356 HGHLYTPGQEITN-DCEQCVCNAGRWVCKDLPC------------------------PGT 390
Query: 364 CTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVK-NDARRTRSFSWTKSVE 422
C + G H TFDG+T+ F G C YVL K + + + +L + T + K+V
Sbjct: 391 CALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDS--YALLGELAPCGSTDKQTCLKTVV 448
Query: 423 LVLGESR--VSLQQHLTVRWNGSRIALPCRAPHFHIDL-DGYLLKVTTKAGLEISWDGDS 479
L+ + + V + +V N ++ LP F + Y + V+ G+ +
Sbjct: 449 LLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAP 508
Query: 480 FVEVMAA--PHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
+++ +G++ GLCGN+NG + DD G + FA +W+ +S+ C+
Sbjct: 509 VMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS--CH-D 565
Query: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
+ + + C ++ A C LK E F CHS VD A +Y+ C D C C ++
Sbjct: 566 KLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNE 625
Query: 596 NCYCESFLAYTRACQREGIKVHW---EPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEI 652
+C C + +Y RAC +G+ + W E N C + V+ C +TC + +E
Sbjct: 626 DCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE- 683
Query: 653 GPCNKPC------VAGCHCPANLVL-HKGRCIKPVLC 682
+ C V GC CP + L KGRC+ C
Sbjct: 684 --ADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKC 718
Score = 115 bits (287), Expect = 2e-25
Identities = 100/383 (26%), Positives = 154/383 (40%), Gaps = 29/383 (7%)
Query: 309 QDGEMWSSINCTICACVKGRT-ECRNKQCIP--ISSCPQG----KILNRKGCCPICTEKP 361
Q+ E W +C + C T E +C P + +C G ++ + GCC E
Sbjct: 4420 QENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCC-WHWECD 4478
Query: 362 GVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-------DARRTRS 414
CT +GDPHY TFDG +++QG C YVL ++ S F V + N R+
Sbjct: 4479 CYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRT 4538
Query: 415 FSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDG--YLLKVTTKAGLE 472
+ VL ++ + + V+ N +ALP + + G Y++ + + G+
Sbjct: 4539 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI-PELGVL 4597
Query: 473 ISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNE 532
+S++G SF + G CG DD I G + + A+ W V
Sbjct: 4598 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPS 4657
Query: 533 FCNRPQRKPVPELCQGTVK--VKLRAHRE------CQKLKSWEFQTCHSTVDYATFYRSC 584
+ P + TV K H++ CQ +K F CH+ V +Y +C
Sbjct: 4658 KPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDAC 4717
Query: 585 VTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAA-TQCKHGAVYDTCGPGCI 643
V D C P + C S AY C ++ I + W + A +C Y CGP
Sbjct: 4718 VFDSCFMP-GSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEE 4776
Query: 644 KTCDNWNEIGPCNKPCVAGCHCP 666
TC + + N V GC CP
Sbjct: 4777 PTCKS-SSSQQNNTVLVEGCFCP 4798
Score = 40.8 bits (94), Expect = 0.004
Identities = 65/277 (23%), Positives = 92/277 (33%), Gaps = 56/277 (20%)
Query: 99 GACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQC---QEGVVTESGVRCVVHCKNPLEH 155
GAC +C + ++ PAE + Q V G C N
Sbjct: 4756 GACLVECPS--------HREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPG 4807
Query: 156 LGMCCPTCPGCVF-EGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSH 214
+C TC GCV + V + GE F+ + C C C G + +
Sbjct: 4808 FDVCVKTC-GCVGPDNVPREFGEHFEFD---CKNCVCLEGGSGII--------------- 4848
Query: 215 IPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSH 274
C PK Q+ V ++V + C C+ +T +CK K
Sbjct: 4849 -----CQPKRCSQKPVTHCVEDGTYLATEVNPADTC-----CNITVCKCNTSLCKEK--- 4895
Query: 275 PGGCDQGQEGCCEECLLRVPP----EDIKVCKFGNKIFQDGEMWSSINCTICAC---VKG 327
P C G E + R P E VC GN +Q G S C C C V
Sbjct: 4896 PSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDN 4955
Query: 328 RTECRNKQCIPI---SSCPQG-KILNRKG-CCPICTE 359
T C + +SC G +++ G CC C +
Sbjct: 4956 NTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQ 4992
Score = 34.3 bits (77), Expect = 0.39
Identities = 39/166 (23%), Positives = 60/166 (36%), Gaps = 41/166 (24%)
Query: 50 CENEGEVLQIPFITDNPCIMCVCLNKEVTCKR-----EKC--PVLSRDC----ALAI-KQ 97
C + G L+ + CVC + + C++ + C P + DC ALA K
Sbjct: 720 CYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKP 779
Query: 98 RGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLG 157
R C+ Y + CV C +G++ + CVV +
Sbjct: 780 RALSCQTLAAGYYHTECVSG----------CV---CPDGLMDDGRGGCVVEKE------- 819
Query: 158 MCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVC 203
CP CV Y G + + + C C+C GR C + VC
Sbjct: 820 -----CP-CVHNNDLYSSGAKIKVD---CNTCTCKRGRWVCTQAVC 856
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 162 bits (410), Expect = 1e-39
Identities = 139/564 (24%), Positives = 215/564 (38%), Gaps = 99/564 (17%)
Query: 133 CQEGVVTESGVRCVVHCKNPLEHLGMCCPTCP-GCVFEGVQYQEGEEFQPEGSKCTKCSC 191
C EG G C H L+ G C P C G+ + G+ + +C C
Sbjct: 589 CLEGFAPVDGCGCPDHTF--LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCV---C 643
Query: 192 TGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSF 251
GR C + SC H+ + + SC + + +
Sbjct: 644 RDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRAL-----SCQTLA------AGY 692
Query: 252 LYDNCTA-CTCRDSTVVCKRKCSHPGGCDQGQEGCC--EECLLRVPPEDIKVCKFGNKIF 308
+ C + C C D G D G+ GC +EC C N ++
Sbjct: 693 YHTECVSGCVCPD------------GLMDDGRGGCVVEKEC----------PCVHNNDLY 730
Query: 309 QDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFG 368
G ++C C C +GR C C G C+++G
Sbjct: 731 SSGAK-IKVDCNTCTCKRGRWVCTQAVC------------------------HGTCSIYG 765
Query: 369 DPHYNTFDGRTFNFQGTCQYVLTKDC---SSPASPFQVLVKNDARRTRSFSWTKSVELVL 425
HY TFDG+ ++F G C YV +D +S F ++ +N T + +K++++ +
Sbjct: 766 SGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFM 825
Query: 426 GESRVSLQ-QHLTV--RWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVE 482
G + + L+ +H V R G +A R G L V + G+ + WD + V
Sbjct: 826 GRTELKLEDKHRVVIQRDEGHHVAYTTREV-------GQYLVVESSTGIIVIWDKRTTVF 878
Query: 483 VMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPV 542
+ AP KG +CGLCGN++ +D D DF SW+ E P
Sbjct: 879 IKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----EAPTCPDVSTN 934
Query: 543 PELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKN--CYCE 600
PE C + A ++C LKS F CHS VD FY +CV D C C + C+C
Sbjct: 935 PEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCS 994
Query: 601 SFLAYTRACQREGIKVHWEPQQNC--------AATQCKHGAVYDTCGPGCIKTCDNWNEI 652
+ +Y + C +EG V W C +C+ Y+ CG +TC N I
Sbjct: 995 AVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWH--YEPCGNRSFETCRTINGI 1052
Query: 653 -GPCNKPCVAGCH--CPANLVLHK 673
+ + GC+ CP + +++
Sbjct: 1053 HSNISVSYLEGCYPRCPKDRPIYE 1076
Score = 137 bits (345), Expect = 3e-32
Identities = 86/312 (27%), Positives = 137/312 (43%), Gaps = 18/312 (5%)
Query: 363 VCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVE 422
VC+ +G+ HY TFDG F F G C Y DC F V +K + + + +S+
Sbjct: 36 VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESIL 95
Query: 423 LVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVE 482
L + + + L +HL V NG+ ++ P +P I+ KV ++AGL + W+ + +
Sbjct: 96 LTIKDDTIYLTRHLAV-LNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALM 154
Query: 483 VMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV-ESNEFCNRPQRKP 541
+ + CGLCG+YNG + DG F +F ++ + + C P+ +
Sbjct: 155 LELDTKFRNHTCGLCGDYNGLQSYSEFLSDG-VLFSPLEFGNMQKINQPDVVCEDPEEEV 213
Query: 542 VPELCQGTVKVKLRAHR-ECQKLKSWE-FQTCHSTVDYATFYRSCVTDMCECPVHKNCYC 599
P C HR EC++L + E F C V + R+C D C CP C C
Sbjct: 214 APASCS--------EHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVC 265
Query: 600 ESFLAYTRACQREGIKV-HWEPQQNC----AATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
+ ++R C G + +W + A+ C VY G C+ TC +
Sbjct: 266 STVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSL 325
Query: 655 CNKPCVAGCHCP 666
C + + GC CP
Sbjct: 326 CEEHRMDGCFCP 337
Score = 115 bits (287), Expect = 2e-25
Identities = 100/383 (26%), Positives = 154/383 (40%), Gaps = 29/383 (7%)
Query: 309 QDGEMWSSINCTICACVKGRT-ECRNKQCIP--ISSCPQG----KILNRKGCCPICTEKP 361
Q+ E W +C + C T E +C P + +C G ++ + GCC E
Sbjct: 1880 QENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCC-WHWECD 1938
Query: 362 GVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-------DARRTRS 414
CT +GDPHY TFDG +++QG C YVL ++ S F V + N R+
Sbjct: 1939 CYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRT 1998
Query: 415 FSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDG--YLLKVTTKAGLE 472
+ VL ++ + + V+ N +ALP + + G Y++ + + G+
Sbjct: 1999 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI-PELGVL 2057
Query: 473 ISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNE 532
+S++G SF + G CG DD I G + + A+ W V
Sbjct: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPS 2117
Query: 533 FCNRPQRKPVPELCQGTVK--VKLRAHRE------CQKLKSWEFQTCHSTVDYATFYRSC 584
+ P + TV K H++ CQ +K F CH+ V +Y +C
Sbjct: 2118 KPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDAC 2177
Query: 585 VTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAA-TQCKHGAVYDTCGPGCI 643
V D C P + C S AY C ++ I + W + A +C Y CGP
Sbjct: 2178 VFDSCFMP-GSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEE 2236
Query: 644 KTCDNWNEIGPCNKPCVAGCHCP 666
TC + + N V GC CP
Sbjct: 2237 PTCKS-SSSQQNNTVLVEGCFCP 2258
Score = 89.0 bits (219), Expect = 1e-17
Identities = 62/205 (30%), Positives = 96/205 (46%), Gaps = 19/205 (9%)
Query: 490 KGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGT 549
+G++ GLCGN+NG + DD G + FA +W+ +S+ C+ + + + C
Sbjct: 422 QGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS--CH-DKLDWLDDPCSLN 478
Query: 550 VKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTR 607
++ A C LK E F CHS VD A +Y+ C D C C +++C C + +Y R
Sbjct: 479 IESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYAR 538
Query: 608 ACQREGIKVHW---EPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPC----- 659
AC +G+ + W E N C + V+ C +TC + +E + C
Sbjct: 539 ACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFA 594
Query: 660 -VAGCHCPANLVL-HKGRCIKPVLC 682
V GC CP + L KGRC+ C
Sbjct: 595 PVDGCGCPDHTFLDEKGRCVPLAKC 619
Score = 40.8 bits (94), Expect = 0.004
Identities = 65/277 (23%), Positives = 92/277 (33%), Gaps = 56/277 (20%)
Query: 99 GACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQC---QEGVVTESGVRCVVHCKNPLEH 155
GAC +C + ++ PAE + Q V G C N
Sbjct: 2216 GACLVECPS--------HREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPG 2267
Query: 156 LGMCCPTCPGCVF-EGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSH 214
+C TC GCV + V + GE F+ + C C C G + +
Sbjct: 2268 FDVCVKTC-GCVGPDNVPREFGEHFEFD---CKNCVCLEGGSGII--------------- 2308
Query: 215 IPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSH 274
C PK Q+ V ++V + C C+ +T +CK K
Sbjct: 2309 -----CQPKRCSQKPVTHCVEDGTYLATEVNPADTC-----CNITVCKCNTSLCKEK--- 2355
Query: 275 PGGCDQGQEGCCEECLLRVPP----EDIKVCKFGNKIFQDGEMWSSINCTICAC---VKG 327
P C G E + R P E VC GN +Q G S C C C V
Sbjct: 2356 PSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDN 2415
Query: 328 RTECRNKQCIPI---SSCPQG-KILNRKG-CCPICTE 359
T C + +SC G +++ G CC C +
Sbjct: 2416 NTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQ 2452
Score = 34.3 bits (77), Expect = 0.39
Identities = 39/166 (23%), Positives = 60/166 (36%), Gaps = 41/166 (24%)
Query: 50 CENEGEVLQIPFITDNPCIMCVCLNKEVTCKR-----EKC--PVLSRDC----ALAI-KQ 97
C + G L+ + CVC + + C++ + C P + DC ALA K
Sbjct: 621 CYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKP 680
Query: 98 RGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLG 157
R C+ Y + CV C +G++ + CVV +
Sbjct: 681 RALSCQTLAAGYYHTECVSG----------CV---CPDGLMDDGRGGCVVEKE------- 720
Query: 158 MCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVC 203
CP CV Y G + + + C C+C GR C + VC
Sbjct: 721 -----CP-CVHNNDLYSSGAKIKVD---CNTCTCKRGRWVCTQAVC 757
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 159 bits (403), Expect = 6e-39
Identities = 98/330 (29%), Positives = 145/330 (43%), Gaps = 10/330 (3%)
Query: 360 KPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSWT 418
+ G+C +G H+ TFDG + F G C Y+ KDC + V V N + S +S
Sbjct: 60 RDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCY 119
Query: 419 KSVELVLG-ESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDG 477
+S+ L + + + H ++ NG + LP I+ + V T G ++WDG
Sbjct: 120 RSISLFFSNQEEIRIYGH-EIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDG 178
Query: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN-- 535
S + + + KGK CGLCGNYN + DD I ++ D+ FA SW V++ +
Sbjct: 179 ISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCV 238
Query: 536 -RPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVH 594
P P P C + +CQ L + F +CH +D + SCV D+C+
Sbjct: 239 LTPSDFPNP--CSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTD-D 295
Query: 595 KNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIG 653
YC + Y RAC G + W +C V+ C C TC +
Sbjct: 296 DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCL 355
Query: 654 PCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
N C+ GC+CP LV+ G CI CP
Sbjct: 356 GSNLHCLDGCYCPDGLVMDNGTCISLENCP 385
Score = 143 bits (361), Expect = 5e-34
Identities = 125/474 (26%), Positives = 192/474 (40%), Gaps = 52/474 (10%)
Query: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTA----CTCRDSTVVCKRKCSHPGGCDQGQE-- 283
+ PF SC D Y +S + D C CR +T R CSH G Q
Sbjct: 265 LLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYCRAATEYA-RACSHAGYPIQDWRDD 323
Query: 284 --GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI-CACVKGRTECRNKQCIPIS 340
C ++C D C F+ + S+++C C C G N CI +
Sbjct: 324 FPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLV-MDNGTCISLE 382
Query: 341 SCPQG----------KILNRKGCCPI------CTEK--PGVCTVFGDPHYNTFDGRTFNF 382
+CP G KI C CTE+ P C+V GD H+ TFDGR ++F
Sbjct: 383 NCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSF 442
Query: 383 QGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNG 442
G CQY+L K L K + +S+ L+L + + +T+ G
Sbjct: 443 IGMCQYILVKGTGKDKFTI-TLQKAPCEQNLGLVCLQSITLILEDD---FNKQVTLGRGG 498
Query: 443 SRIALPCRAPHFHID-------LDGYLLKVTTKAGLEISW--DGDSFVEVMAAPHLKGKL 493
+ P + F+++ L + + T GL+I + DG+ + + K +
Sbjct: 499 QILTSPNQG--FNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRT 555
Query: 494 CGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQ-GTVKV 552
GLCG +NG+ RDD + G + A +WRV S C P PV + C +
Sbjct: 556 LGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQNI 613
Query: 553 KLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQRE 612
AH C + F CH + +Y+ C D C+C +C C + Y C +
Sbjct: 614 GYAAH--CDVIHQELFAPCHIYISPGLYYQLCRHDACKCG--SSCLCNALAHYAYLCGQH 669
Query: 613 GIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCP 666
G+ + + Q + A C+ G +Y C C+ +C + + C+ C GC+CP
Sbjct: 670 GVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCP 723
Score = 125 bits (313), Expect = 2e-28
Identities = 102/406 (25%), Positives = 162/406 (39%), Gaps = 58/406 (14%)
Query: 238 CLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPED 297
C +R VY G + C C + TV C + P
Sbjct: 743 CHYRGSVYQPGE-LIPTPSGLCQCSNGTVKCDELAT---------------------PSA 780
Query: 298 IKVCKFGNKIFQ----DGEMWSS-INC-TICACVKGRTECRNKQCIPISSCPQGKILNRK 351
+ +C G + F D E+ + +NC T CA + N C P S C G +
Sbjct: 781 VHICPEGKEYFDCRFPDPELPAGGVNCETTCANL-----AMNFTCTPSSPCISGCV---- 831
Query: 352 GCCP-ICTEK---------PGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPF 401
C P +C P VCT++GD HY +FDG +++ CQ L K S+ S
Sbjct: 832 -CAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK--SADDSDI 888
Query: 402 QVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGY 461
V+ +N +KSV + +G++ + L + S L ++ + Y
Sbjct: 889 SVIAQNKKCFDNDIVCSKSVLISVGDTEIYLND-TPYKQKQSGFFLENKSTYQLWKAGYY 947
Query: 462 LLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD 521
++ + + I WD + + + P K KL GLCGN++ +D+ + +
Sbjct: 948 IVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARV 1007
Query: 522 FAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFY 581
F +SW + C P P C+ A +EC L S F +C + +D +F
Sbjct: 1008 FGDSWALGQ---CESPDETIKP--CEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFA 1062
Query: 582 RSCVTDMCECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNCA 625
++C D C C + + C C S AY C +EGI +HW C+
Sbjct: 1063 KNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108
Score = 62.4 bits (150), Expect = 1e-09
Identities = 84/359 (23%), Positives = 130/359 (36%), Gaps = 47/359 (13%)
Query: 348 LNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN 407
+N CCP E P C++ + TFDG Y+L + P +++V +
Sbjct: 1426 VNSDICCPEW-ECPCRCSMLSELSIITFDGNNAALYSMASYILVR------IPGEIIVAH 1478
Query: 408 DARRTRSFSWTKSVE-LVLGESRVSLQQHLTVRWNGSR--------IALPCRAPHFHIDL 458
+ + + + + + L + V+ H + +R + LP + I+
Sbjct: 1479 IEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIED 1538
Query: 459 DGYLLKVTTKAGLEISWD---GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNF 515
G + +TT AGL I W G + +L GLCG N DDL +G
Sbjct: 1539 SGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTI 1598
Query: 516 KFDVDD---FAESWRVESN--EFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQT 570
+++D F ESW +E + RP R C + + L F
Sbjct: 1599 ITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDL----------LNRRIFIP 1648
Query: 571 CHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCK 630
CH V F C N C++ AY C + I + W C+ + C
Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQWRTPDYCSLS-CP 1704
Query: 631 HGAVYDTCGPGC-IKTCDNWNEIGPCNKPCV---AGCHCPANLVLHK---GRCIKPVLC 682
G Y C C +TC N G + C+ C C VLH+ +CI C
Sbjct: 1705 EGKEYQPCVRPCEARTCLNQWFYG--HTSCLNLREDCVCKVGTVLHRPHSAQCIPEKEC 1761
Score = 43.9 bits (102), Expect = 5e-04
Identities = 87/392 (22%), Positives = 140/392 (35%), Gaps = 100/392 (25%)
Query: 22 TCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNKEVTCKR 81
TCC + C ++ S+ C N +++ + +P + C + C
Sbjct: 1825 TCCSKEVCGCD-------TTLCETSIPTCTNSQKLI----VGHSP--LSCCPQYKCECDP 1871
Query: 82 EKCPVLSR-DCA-----LAIKQRGACCEQ----CKGCT------YEGNTYN---SSFKWQ 122
KCP +S +C + ++Q CC C+ CT ++G +S +
Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931
Query: 123 SPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHL-GMCCPT------CPGCVFEGVQYQE 175
P CV C+ + + C E++ G CCPT C V +
Sbjct: 1932 CPQYYCV---CEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEV-- 1986
Query: 176 GEEFQPEGSKCTKCSCTGGRTQCVRE-VCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLP 234
GE + + + C C + C ++ VC Q +S + PGQ K L + + +
Sbjct: 1987 GEFTAIDHNFQSDCGCI--QYLCEKDDVCVF----QEVSVLNPGQSMIKYLEEDFCYTI- 2039
Query: 235 FGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294
CL + DN + F N T C V + P GCC C
Sbjct: 2040 --ECL---EEKDNHTGFHTLNFTLVNCSKKCDVHQVYTPSPS-----DYGCCGTC----- 2084
Query: 295 PEDIKVCKFGNK-----IFQDGEMWSSINCTICACVK-----------------GRTECR 332
+++ CKF + ++ G W NCT CVK TEC+
Sbjct: 2085 -KNVS-CKFHMENGTSVVYAVGSTWH-YNCTTYECVKTDEGAIILNYTMVCPPFNETECK 2141
Query: 333 NKQCIPISSCPQGKILNRKGCCPICTEKPGVC 364
+ I K+ N +GCC IC + +C
Sbjct: 2142 MSEGIV-------KLYN-EGCCKICKREERIC 2165
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 34/126 (26%)
Query: 82 EKCP--VLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVT 139
+KC + RDC +CC CT+E S+ + C C +G+V
Sbjct: 329 DKCDDSFVHRDCI-------SCCPPT--CTFEKQCLGSNLHC---LDGCY---CPDGLVM 373
Query: 140 ESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCV 199
++G C+ LE+ CP C F G+ Y G + + E CT+C C GG C
Sbjct: 374 DNGT-CI-----SLEN-------CP-CGFHGLAYSVGSKIEQE---CTECVCVGGVWNCT 416
Query: 200 REVCPI 205
+ CP+
Sbjct: 417 EQDCPV 422
Score = 33.5 bits (75), Expect = 0.67
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
Query: 635 YDTCGPGCIKTCDNWNEIGPCNKPCVAGC--HCPANLVLHKG--RCIKPVLC 682
Y+ C C KTC + + P V GC +CP N++L + +C+ P C
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Score = 30.4 bits (67), Expect = 5.7
Identities = 45/210 (21%), Positives = 69/210 (32%), Gaps = 64/210 (30%)
Query: 159 CCPTCPGCVFEGVQYQEGEEFQP-----EGSKCTK------CSCTGGRTQCVREVCPILS 207
C +CP EG+E+QP E C SC R CV +V +L
Sbjct: 1699 CSLSCP----------EGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLH 1748
Query: 208 CPQHLSHIPPGQC-CPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTV 266
P IP +C C Q + ++++ G D CT C ++
Sbjct: 1749 RPHSAQCIPEKECACTDSEDQPRT----------AGEIWNGG----IDECTLYKCLENGS 1794
Query: 267 VCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVK 326
+ + CD+ CE + + + W+ + +C C
Sbjct: 1795 IIPIE----PDCDEEPTPVCE--------------REAEVVMGIIDKWTCCSKEVCGCDT 1836
Query: 327 GRTE-----CRNKQCI-----PISSCPQGK 346
E C N Q + P+S CPQ K
Sbjct: 1837 TLCETSIPTCTNSQKLIVGHSPLSCCPQYK 1866
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 159 bits (403), Expect = 6e-39
Identities = 98/330 (29%), Positives = 145/330 (43%), Gaps = 10/330 (3%)
Query: 360 KPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSWT 418
+ G+C +G H+ TFDG + F G C Y+ KDC + V V N + S +S
Sbjct: 60 RDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCY 119
Query: 419 KSVELVLG-ESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDG 477
+S+ L + + + H ++ NG + LP I+ + V T G ++WDG
Sbjct: 120 RSISLFFSNQEEIRIYGH-EIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDG 178
Query: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN-- 535
S + + + KGK CGLCGNYN + DD I ++ D+ FA SW V++ +
Sbjct: 179 ISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCV 238
Query: 536 -RPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVH 594
P P P C + +CQ L + F +CH +D + SCV D+C+
Sbjct: 239 LTPSDFPNP--CSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTD-D 295
Query: 595 KNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIG 653
YC + Y RAC G + W +C V+ C C TC +
Sbjct: 296 DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCL 355
Query: 654 PCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
N C+ GC+CP LV+ G CI CP
Sbjct: 356 GSNLHCLDGCYCPDGLVMDNGTCISLENCP 385
Score = 143 bits (361), Expect = 5e-34
Identities = 125/474 (26%), Positives = 192/474 (40%), Gaps = 52/474 (10%)
Query: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTA----CTCRDSTVVCKRKCSHPGGCDQGQE-- 283
+ PF SC D Y +S + D C CR +T R CSH G Q
Sbjct: 265 LLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYCRAATEYA-RACSHAGYPIQDWRDD 323
Query: 284 --GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI-CACVKGRTECRNKQCIPIS 340
C ++C D C F+ + S+++C C C G N CI +
Sbjct: 324 FPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLV-MDNGTCISLE 382
Query: 341 SCPQG----------KILNRKGCCPI------CTEK--PGVCTVFGDPHYNTFDGRTFNF 382
+CP G KI C CTE+ P C+V GD H+ TFDGR ++F
Sbjct: 383 NCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSF 442
Query: 383 QGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNG 442
G CQY+L K L K + +S+ L+L + + +T+ G
Sbjct: 443 IGMCQYILVKGTGKDKFTI-TLQKAPCEQNLGLVCLQSITLILEDD---FNKQVTLGRGG 498
Query: 443 SRIALPCRAPHFHID-------LDGYLLKVTTKAGLEISW--DGDSFVEVMAAPHLKGKL 493
+ P + F+++ L + + T GL+I + DG+ + + K +
Sbjct: 499 QILTSPNQG--FNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRT 555
Query: 494 CGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQ-GTVKV 552
GLCG +NG+ RDD + G + A +WRV S C P PV + C +
Sbjct: 556 LGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQNI 613
Query: 553 KLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQRE 612
AH C + F CH + +Y+ C D C+C +C C + Y C +
Sbjct: 614 GYAAH--CDVIHQELFAPCHIYISPGLYYQLCRHDACKCG--SSCLCNALAHYAYLCGQH 669
Query: 613 GIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCP 666
G+ + + Q + A C+ G +Y C C+ +C + + C+ C GC+CP
Sbjct: 670 GVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCP 723
Score = 125 bits (313), Expect = 2e-28
Identities = 102/406 (25%), Positives = 162/406 (39%), Gaps = 58/406 (14%)
Query: 238 CLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPED 297
C +R VY G + C C + TV C + P
Sbjct: 743 CHYRGSVYQPGE-LIPTPSGLCQCSNGTVKCDELAT---------------------PSA 780
Query: 298 IKVCKFGNKIFQ----DGEMWSS-INC-TICACVKGRTECRNKQCIPISSCPQGKILNRK 351
+ +C G + F D E+ + +NC T CA + N C P S C G +
Sbjct: 781 VHICPEGKEYFDCRFPDPELPAGGVNCETTCANL-----AMNFTCTPSSPCISGCV---- 831
Query: 352 GCCP-ICTEK---------PGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPF 401
C P +C P VCT++GD HY +FDG +++ CQ L K S+ S
Sbjct: 832 -CAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK--SADDSDI 888
Query: 402 QVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGY 461
V+ +N +KSV + +G++ + L + S L ++ + Y
Sbjct: 889 SVIAQNKKCFDNDIVCSKSVLISVGDTEIYLND-TPYKQKQSGFFLENKSTYQLWKAGYY 947
Query: 462 LLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD 521
++ + + I WD + + + P K KL GLCGN++ +D+ + +
Sbjct: 948 IVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARV 1007
Query: 522 FAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFY 581
F +SW + C P P C+ A +EC L S F +C + +D +F
Sbjct: 1008 FGDSWALGQ---CESPDETIKP--CEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFA 1062
Query: 582 RSCVTDMCECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNCA 625
++C D C C + + C C S AY C +EGI +HW C+
Sbjct: 1063 KNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108
Score = 62.0 bits (149), Expect = 2e-09
Identities = 83/359 (23%), Positives = 130/359 (36%), Gaps = 47/359 (13%)
Query: 348 LNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN 407
+N CCP E P C++ + TFDG Y+L + P +++V +
Sbjct: 1426 VNSDICCPEW-ECPCRCSMLSELSIITFDGNNAALYSMASYILVR------IPGEIIVAH 1478
Query: 408 DARRTRSFSWTKSVE-LVLGESRVSLQQHLTVRWNGSR--------IALPCRAPHFHIDL 458
+ + + + + + L + V+ H + +R + LP + I+
Sbjct: 1479 IEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIED 1538
Query: 459 DGYLLKVTTKAGLEISWD---GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNF 515
G + +TT AGL I W G + +L GLCG N DDL +G
Sbjct: 1539 SGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTI 1598
Query: 516 KFDVDD---FAESWRVESN--EFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQT 570
+++D F ESW +E + RP R C + + L F
Sbjct: 1599 ITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDL----------LNRRIFIP 1648
Query: 571 CHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCK 630
CH V F C N C++ AY C + I + W C+ + C
Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQWRTPDYCSLS-CP 1704
Query: 631 HGAVYDTCGPGC-IKTCDNWNEIGPCNKPCV---AGCHCPANLVLHK---GRCIKPVLC 682
G Y C C +TC N G + C+ C C +LH+ +CI C
Sbjct: 1705 EGKEYQPCVRPCEARTCLNQWFYG--HTSCLNLREDCVCKVGTILHRPHSAQCIPEKEC 1761
Score = 43.9 bits (102), Expect = 5e-04
Identities = 87/392 (22%), Positives = 140/392 (35%), Gaps = 100/392 (25%)
Query: 22 TCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNKEVTCKR 81
TCC + C ++ S+ C N +++ + +P + C + C
Sbjct: 1825 TCCSKEVCGCD-------TTLCETSIPTCTNSQKLI----VGHSP--LSCCPQYKCECDP 1871
Query: 82 EKCPVLSR-DCA-----LAIKQRGACCEQ----CKGCT------YEGNTYN---SSFKWQ 122
KCP +S +C + ++Q CC C+ CT ++G +S +
Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931
Query: 123 SPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHL-GMCCPT------CPGCVFEGVQYQE 175
P CV C+ + + C E++ G CCPT C V +
Sbjct: 1932 CPQYYCV---CEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEV-- 1986
Query: 176 GEEFQPEGSKCTKCSCTGGRTQCVRE-VCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLP 234
GE + + + C C + C ++ VC Q +S + PGQ K L + + +
Sbjct: 1987 GEFTAIDHNFQSDCGCI--QYLCEKDDVCVF----QEVSVLNPGQSMIKYLEEDFCYTI- 2039
Query: 235 FGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294
CL + DN + F N T C V + P GCC C
Sbjct: 2040 --ECL---EEKDNHTGFHTLNFTLVNCSKKCDVHQVYTPSPS-----DYGCCGTC----- 2084
Query: 295 PEDIKVCKFGNK-----IFQDGEMWSSINCTICACVK-----------------GRTECR 332
+++ CKF + ++ G W NCT CVK TEC+
Sbjct: 2085 -KNVS-CKFHMENGTSVVYAVGSTWH-YNCTTYECVKTDEGAIILNYTMVCPPFNETECK 2141
Query: 333 NKQCIPISSCPQGKILNRKGCCPICTEKPGVC 364
+ I K+ N +GCC IC + +C
Sbjct: 2142 MNEGIV-------KLYN-EGCCKICKREERIC 2165
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 34/126 (26%)
Query: 82 EKCP--VLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVT 139
+KC + RDC +CC CT+E S+ + C C +G+V
Sbjct: 329 DKCDDSFVHRDCI-------SCCPPT--CTFEKQCLGSNLHC---LDGCY---CPDGLVM 373
Query: 140 ESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCV 199
++G C+ LE+ CP C F G+ Y G + + E CT+C C GG C
Sbjct: 374 DNGT-CI-----SLEN-------CP-CGFHGLAYSVGSKIEQE---CTECVCVGGVWNCT 416
Query: 200 REVCPI 205
+ CP+
Sbjct: 417 EQDCPV 422
Score = 33.5 bits (75), Expect = 0.67
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
Query: 635 YDTCGPGCIKTCDNWNEIGPCNKPCVAGC--HCPANLVLHKG--RCIKPVLC 682
Y+ C C KTC + + P V GC +CP N++L + +C+ P C
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Score = 30.8 bits (68), Expect = 4.3
Identities = 46/210 (21%), Positives = 69/210 (32%), Gaps = 64/210 (30%)
Query: 159 CCPTCPGCVFEGVQYQEGEEFQP-----EGSKCTK------CSCTGGRTQCVREVCPILS 207
C +CP EG+E+QP E C SC R CV +V IL
Sbjct: 1699 CSLSCP----------EGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILH 1748
Query: 208 CPQHLSHIPPGQC-CPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTV 266
P IP +C C Q + ++++ G D CT C ++
Sbjct: 1749 RPHSAQCIPEKECACTDSEDQPRT----------AGEIWNGG----IDECTLYKCLENGS 1794
Query: 267 VCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVK 326
+ + CD+ CE + + + W+ + +C C
Sbjct: 1795 IIPIE----PDCDEEPTPVCE--------------REAEVVMGIIDKWTCCSKEVCGCDT 1836
Query: 327 GRTE-----CRNKQCI-----PISSCPQGK 346
E C N Q + P+S CPQ K
Sbjct: 1837 TLCETSIPTCTNSQKLIVGHSPLSCCPQYK 1866
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo
sapiens]
Length = 2250
Score = 159 bits (403), Expect = 6e-39
Identities = 98/330 (29%), Positives = 145/330 (43%), Gaps = 10/330 (3%)
Query: 360 KPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSWT 418
+ G+C +G H+ TFDG + F G C Y+ KDC + V V N + S +S
Sbjct: 60 RDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCY 119
Query: 419 KSVELVLG-ESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDG 477
+S+ L + + + H ++ NG + LP I+ + V T G ++WDG
Sbjct: 120 RSISLFFSNQEEIRIYGH-EIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDG 178
Query: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN-- 535
S + + + KGK CGLCGNYN + DD I ++ D+ FA SW V++ +
Sbjct: 179 ISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCV 238
Query: 536 -RPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVH 594
P P P C + +CQ L + F +CH +D + SCV D+C+
Sbjct: 239 LTPSDFPNP--CSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTD-D 295
Query: 595 KNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIG 653
YC + Y RAC G + W +C V+ C C TC +
Sbjct: 296 DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCL 355
Query: 654 PCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
N C+ GC+CP LV+ G CI CP
Sbjct: 356 GSNLHCLDGCYCPDGLVMDNGTCISLENCP 385
Score = 143 bits (361), Expect = 5e-34
Identities = 125/474 (26%), Positives = 192/474 (40%), Gaps = 52/474 (10%)
Query: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTA----CTCRDSTVVCKRKCSHPGGCDQGQE-- 283
+ PF SC D Y +S + D C CR +T R CSH G Q
Sbjct: 265 LLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYCRAATEYA-RACSHAGYPIQDWRDD 323
Query: 284 --GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI-CACVKGRTECRNKQCIPIS 340
C ++C D C F+ + S+++C C C G N CI +
Sbjct: 324 FPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLV-MDNGTCISLE 382
Query: 341 SCPQG----------KILNRKGCCPI------CTEK--PGVCTVFGDPHYNTFDGRTFNF 382
+CP G KI C CTE+ P C+V GD H+ TFDGR ++F
Sbjct: 383 NCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSF 442
Query: 383 QGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNG 442
G CQY+L K L K + +S+ L+L + + +T+ G
Sbjct: 443 IGMCQYILVKGTGKDKFTI-TLQKAPCEQNLGLVCLQSITLILEDD---FNKQVTLGRGG 498
Query: 443 SRIALPCRAPHFHID-------LDGYLLKVTTKAGLEISW--DGDSFVEVMAAPHLKGKL 493
+ P + F+++ L + + T GL+I + DG+ + + K +
Sbjct: 499 QILTSPNQG--FNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRT 555
Query: 494 CGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQ-GTVKV 552
GLCG +NG+ RDD + G + A +WRV S C P PV + C +
Sbjct: 556 LGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQNI 613
Query: 553 KLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQRE 612
AH C + F CH + +Y+ C D C+C +C C + Y C +
Sbjct: 614 GYAAH--CDVIHQELFAPCHIYISPGLYYQLCRHDACKCG--SSCLCNALAHYAYLCGQH 669
Query: 613 GIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCP 666
G+ + + Q + A C+ G +Y C C+ +C + + C+ C GC+CP
Sbjct: 670 GVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCP 723
Score = 125 bits (313), Expect = 2e-28
Identities = 102/406 (25%), Positives = 162/406 (39%), Gaps = 58/406 (14%)
Query: 238 CLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPED 297
C +R VY G + C C + TV C + P
Sbjct: 743 CHYRGSVYQPGE-LIPTPSGLCQCSNGTVKCDELAT---------------------PSA 780
Query: 298 IKVCKFGNKIFQ----DGEMWSS-INC-TICACVKGRTECRNKQCIPISSCPQGKILNRK 351
+ +C G + F D E+ + +NC T CA + N C P S C G +
Sbjct: 781 VHICPEGKEYFDCRFPDPELPAGGVNCETTCANL-----AMNFTCTPSSPCISGCV---- 831
Query: 352 GCCP-ICTEK---------PGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPF 401
C P +C P VCT++GD HY +FDG +++ CQ L K S+ S
Sbjct: 832 -CAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK--SADDSDI 888
Query: 402 QVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGY 461
V+ +N +KSV + +G++ + L + S L ++ + Y
Sbjct: 889 SVIAQNKKCFDNDIVCSKSVLISVGDTEIYLND-TPYKQKQSGFFLENKSTYQLWKAGYY 947
Query: 462 LLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD 521
++ + + I WD + + + P K KL GLCGN++ +D+ + +
Sbjct: 948 IVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARV 1007
Query: 522 FAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFY 581
F +SW + C P P C+ A +EC L S F +C + +D +F
Sbjct: 1008 FGDSWALGQ---CESPDETIKP--CEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFA 1062
Query: 582 RSCVTDMCECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNCA 625
++C D C C + + C C S AY C +EGI +HW C+
Sbjct: 1063 KNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108
Score = 62.0 bits (149), Expect = 2e-09
Identities = 83/359 (23%), Positives = 130/359 (36%), Gaps = 47/359 (13%)
Query: 348 LNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN 407
+N CCP E P C++ + TFDG Y+L + P +++V +
Sbjct: 1426 VNSDICCPEW-ECPCRCSMLSELSIITFDGNNAALYSMASYILVR------IPGEIIVAH 1478
Query: 408 DARRTRSFSWTKSVE-LVLGESRVSLQQHLTVRWNGSR--------IALPCRAPHFHIDL 458
+ + + + + + L + V+ H + +R + LP + I+
Sbjct: 1479 IEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIED 1538
Query: 459 DGYLLKVTTKAGLEISWD---GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNF 515
G + +TT AGL I W G + +L GLCG N DDL +G
Sbjct: 1539 SGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTI 1598
Query: 516 KFDVDD---FAESWRVESN--EFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQT 570
+++D F ESW +E + RP R C + + L F
Sbjct: 1599 ITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDL----------LNRRIFIP 1648
Query: 571 CHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCK 630
CH V F C N C++ AY C + I + W C+ + C
Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQWRTPDYCSLS-CP 1704
Query: 631 HGAVYDTCGPGC-IKTCDNWNEIGPCNKPCV---AGCHCPANLVLHK---GRCIKPVLC 682
G Y C C +TC N G + C+ C C +LH+ +CI C
Sbjct: 1705 EGKEYQPCVRPCEARTCLNQWFYG--HTSCLNLREDCVCKVGTILHRPHSAQCIPEKEC 1761
Score = 43.1 bits (100), Expect = 8e-04
Identities = 86/392 (21%), Positives = 140/392 (35%), Gaps = 100/392 (25%)
Query: 22 TCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNKEVTCKR 81
TCC + C ++ S+ C N +++ + +P + C + C
Sbjct: 1825 TCCSKEVCGCD-------TTLCETSIPTCTNSQKLI----VGHSP--LSCCPQYKCECDP 1871
Query: 82 EKCPVLSR-DCA-----LAIKQRGACCEQ----CKGCT------YEGNTYN---SSFKWQ 122
KCP +S +C + ++Q CC C+ CT ++G +S +
Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931
Query: 123 SPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHL-GMCCPT------CPGCVFEGVQYQE 175
P CV C+ + + C E++ G CCPT C + +
Sbjct: 1932 CPQYYCV---CEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLIMPTCEV-- 1986
Query: 176 GEEFQPEGSKCTKCSCTGGRTQCVRE-VCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLP 234
GE + + + C C + C ++ VC Q +S + PGQ K L + + +
Sbjct: 1987 GEFTAIDHNFQSDCGCI--QYLCEKDDVCVF----QEVSVLNPGQSMIKYLEEDFCYAI- 2039
Query: 235 FGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294
CL + DN + F N T C V + P GCC C
Sbjct: 2040 --ECL---EEKDNHTGFHTLNFTLVNCSKKCDVHQVYTPSPS-----DYGCCGTC----- 2084
Query: 295 PEDIKVCKFGNK-----IFQDGEMWSSINCTICACVK-----------------GRTECR 332
+++ CKF + ++ G W NCT CVK TEC+
Sbjct: 2085 -KNVS-CKFHMENGTSVVYAVGSTWH-YNCTTYECVKTDEGAIILNYTMVCPPFNETECK 2141
Query: 333 NKQCIPISSCPQGKILNRKGCCPICTEKPGVC 364
+ I K+ N +GCC IC + +C
Sbjct: 2142 MNEGIV-------KLYN-EGCCKICKREERIC 2165
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 34/126 (26%)
Query: 82 EKCP--VLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVT 139
+KC + RDC +CC CT+E S+ + C C +G+V
Sbjct: 329 DKCDDSFVHRDCI-------SCCPPT--CTFEKQCLGSNLHC---LDGCY---CPDGLVM 373
Query: 140 ESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCV 199
++G C+ LE+ CP C F G+ Y G + + E CT+C C GG C
Sbjct: 374 DNGT-CI-----SLEN-------CP-CGFHGLAYSVGSKIEQE---CTECVCVGGVWNCT 416
Query: 200 REVCPI 205
+ CP+
Sbjct: 417 EQDCPV 422
Score = 33.5 bits (75), Expect = 0.67
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
Query: 635 YDTCGPGCIKTCDNWNEIGPCNKPCVAGC--HCPANLVLHKG--RCIKPVLC 682
Y+ C C KTC + + P V GC +CP N++L + +C+ P C
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Score = 30.8 bits (68), Expect = 4.3
Identities = 46/210 (21%), Positives = 69/210 (32%), Gaps = 64/210 (30%)
Query: 159 CCPTCPGCVFEGVQYQEGEEFQP-----EGSKCTK------CSCTGGRTQCVREVCPILS 207
C +CP EG+E+QP E C SC R CV +V IL
Sbjct: 1699 CSLSCP----------EGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILH 1748
Query: 208 CPQHLSHIPPGQC-CPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTV 266
P IP +C C Q + ++++ G D CT C ++
Sbjct: 1749 RPHSAQCIPEKECACTDSEDQPRT----------AGEIWNGG----IDECTLYKCLENGS 1794
Query: 267 VCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVK 326
+ + CD+ CE + + + W+ + +C C
Sbjct: 1795 IIPIE----PDCDEEPTPVCE--------------REAEVVMGIIDKWTCCSKEVCGCDT 1836
Query: 327 GRTE-----CRNKQCI-----PISSCPQGK 346
E C N Q + P+S CPQ K
Sbjct: 1837 TLCETSIPTCTNSQKLIVGHSPLSCCPQYK 1866
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 157 bits (397), Expect = 3e-38
Identities = 152/613 (24%), Positives = 229/613 (37%), Gaps = 130/613 (21%)
Query: 100 ACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMC 159
AC C+G + T + SF P + C C G L G C
Sbjct: 1366 ACQPTCRGLSEADVTCSVSFV---PVDGCT---CPAGTF--------------LNDAGAC 1405
Query: 160 CPT--CPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCV-REVCPILSCPQHLSHIP 216
P CP C G GE EG+ C SCTGG+ C+ + C + ++
Sbjct: 1406 VPAQECP-CYAHGTVLAPGEVVHDEGAVC---SCTGGKLSCLGASLQKSTGCAAPMVYL- 1460
Query: 217 PGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPG 276
C G P CL D G F + C C PG
Sbjct: 1461 --DCSNSSAGT------PGAECLRSCHTLDVGC-FSTHCVSGCVCP------------PG 1499
Query: 277 GCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQC 336
G GC E ED C ++ GE ++C C C R EC ++ C
Sbjct: 1500 LVSDGSGGCIAE-------EDCP-CVHNEATYKPGET-IRVDCNTCTCRNRRWECSHRLC 1550
Query: 337 IPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDC-- 394
+ G C +GD H+ TFDG ++F+G+C+Y+L +D
Sbjct: 1551 L------------------------GTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCG 1586
Query: 395 -SSPASPFQVLVKNDARRTRSFSWTKSVELVLG--------------------ESRVSLQ 433
++ F+++ +N T + +K+++L + E+ V +
Sbjct: 1587 DNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFR 1646
Query: 434 QHLT-------VRWNGSRIAL---PCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEV 483
Q L + G+ A+ P P + I G L + T G+ +SWD + V +
Sbjct: 1647 QRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFI 1705
Query: 484 MAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVP 543
KG++CGLCGN++ + +D + D +F SW++ + C P
Sbjct: 1706 RLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPS--C--PDALAPK 1761
Query: 544 ELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKN--CYCES 601
+ C K A ++C L F C S VD +Y +CV D C C + C+C +
Sbjct: 1762 DPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTA 1821
Query: 602 FLAYTRACQREGIKVHWEPQQNC---AATQCKHGAV---YDTCGPGCIKTCDNWNEIGPC 655
AY +AC G+ V W C HG Y CG C+KTC N +
Sbjct: 1822 VAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLV 1881
Query: 656 NKPCVAGCH--CP 666
+ P + GC+ CP
Sbjct: 1882 DLPGLEGCYPKCP 1894
Score = 142 bits (359), Expect = 8e-34
Identities = 139/532 (26%), Positives = 222/532 (41%), Gaps = 67/532 (12%)
Query: 204 PILSCPQHLSHIPPGQCCPK-CLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR 262
P CP L +P G C + + R + F C D ++ D C TC
Sbjct: 896 PTEQCPDPLP-LPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP 954
Query: 263 DSTVV-CKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIF------QDGEMWS 315
+T V R+C+H GG Q + C E R P +++ + G+ Q ++
Sbjct: 955 CATFVEYSRQCAHAGG--QPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCE 1012
Query: 316 SINCTICACVKGRT-----ECRNKQCIPISSCP---------QGKILNRKGCCPICTEK- 360
C C GR+ + + C+P+ CP G N C CT
Sbjct: 1013 DHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTT--CSSCTCSG 1070
Query: 361 ----------PGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVK-NDA 409
PG C+V G H +T+D + ++ G C YVL+K C+ S F VL +
Sbjct: 1071 GLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCAD--SSFTVLAELRKC 1128
Query: 410 RRTRSFSWTKSVELVL--GESRVSLQQHLTVRWNGSRIALPCRAPHFHIDL-DGYLLKVT 466
T + + K+V L L G++ + +Q V N LP A + + + + V
Sbjct: 1129 GLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQ 1188
Query: 467 TKAGLEISWDGDSFVEVMAA--PHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAE 524
T GL++ ++V P +G++CGLCGN+N ++ DD G + FA
Sbjct: 1189 TGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFAN 1248
Query: 525 SWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLK--SWEFQTCHSTVDYATFYR 582
+W+ ++ C R + C +V+ + A C +L + F CHS ++ F+
Sbjct: 1249 TWKAQAA--CANA-RNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHS 1305
Query: 583 SCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEP------QQNCAATQCKHGAVY 635
+C+ D C C ++C C + +Y AC +G+++ W QNC +Q ++ V
Sbjct: 1306 NCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQ-RYAYVV 1364
Query: 636 DTCGPGCIKTCDNWNEIG-PCNKPCVA--GCHCPANLVLH-KGRCIKPVLCP 683
D C P TC +E C+ V GC CPA L+ G C+ CP
Sbjct: 1365 DACQP----TCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECP 1412
Score = 125 bits (315), Expect = 1e-28
Identities = 93/337 (27%), Positives = 138/337 (40%), Gaps = 39/337 (11%)
Query: 363 VCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN---DARRTRSFSWTK 419
VC+ +GD HY TFDG F F G C YV ++ C + F V ++ +R + K
Sbjct: 732 VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRPVVTRVVIK 791
Query: 420 SVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDS 479
+ LVL S S V NG R LP ++ G +KV+ + L W+G+
Sbjct: 792 AQGLVLEASNGS------VLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGED 845
Query: 480 FVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQR 539
+ P + CGLCG++NG + + +A + R+ +F N +
Sbjct: 846 SALLELDPKYANQTCGLCGDFNGLPAFN------------EFYAHNARLTPLQFGNLQKL 893
Query: 540 KPVPELCQGTVKVKLRAHRE----CQK-LKSWEFQTCHSTVDYATFYRSCVTDMCECPVH 594
E C + + + C + L F CH+ VD + +C D+C CP
Sbjct: 894 DGPTEQCPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCP-- 951
Query: 595 KNCYCESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIG 653
C C +F+ Y+R C G + +W + C T C + CG C TC N
Sbjct: 952 -TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRT-CPLNMQHQECGSPCTDTCSNPQRAQ 1009
Query: 654 PCNKPCVAGCHCPANL-------VLHKGRCIKPVLCP 683
C CV GC CP + H G C+ CP
Sbjct: 1010 LCEDHCVDGCFCPPGRSCTVLDDITHSG-CLPLGQCP 1045
Score = 120 bits (301), Expect = 4e-27
Identities = 88/315 (27%), Positives = 130/315 (41%), Gaps = 20/315 (6%)
Query: 363 VCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVE 422
VC+ +G HY TFDG F F G C YV ++ C + F + ++ R S + T S
Sbjct: 80 VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLR---RSQESAAPTLSRV 136
Query: 423 LVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVE 482
L+ + V +V NG + LP I KV + GL + W+ D +
Sbjct: 137 LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLL 196
Query: 483 VMAAPHLKGKLCGLCGNYNGHK-RDDLIGGDGNFKFDVDDFAESWRVES-NEFCNRPQRK 540
+ K CGLCG++NG +L+ N K +F +++ E C P +
Sbjct: 197 LELDTKYANKTCGLCGDFNGMPVVSELL--SHNTKLTPMEFGNLQKMDDPTEQCQDPVPE 254
Query: 541 PVPELCQGTVKVKLRAHRECQKLKSWE-FQTCHSTVDYATFYRSCVTDMCECPVHK--NC 597
P P C + C++L + F C + VD ++ +C D+C C +C
Sbjct: 255 P-PRNCSTGFGI-------CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
Query: 598 YCESFLAYTRACQRE-GIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCN 656
C + Y+R C G+ W C +C + Y C C TC N C
Sbjct: 307 VCHTLAEYSRQCTHAGGLPQDWRGPDFC-PQKCPNNMQYHECRSPCADTCSNQEHSRACE 365
Query: 657 KPCVAGCHCPANLVL 671
CVAGC CP VL
Sbjct: 366 DHCVAGCFCPEGTVL 380
Score = 108 bits (271), Expect = 1e-23
Identities = 102/433 (23%), Positives = 169/433 (39%), Gaps = 49/433 (11%)
Query: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVK------------GRTECRNKQC-IPISS 341
P C + Q E W+ NCT+ CV C NK I +S
Sbjct: 5323 PSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSD 5382
Query: 342 CPQGKILNRKGCCPIC-----TEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSS 396
Q + + C T G+C+++G HY+TFDG ++ F+G C YVL ++ +
Sbjct: 5383 PSQPCDFHYECECECVGGRGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHA 5442
Query: 397 PASPFQVLVKND------------ARRTRSFS-WTKSVELVLGESRVSLQQHLTVRWNGS 443
+ + N AR R+ S KS+++VL + V ++ + ++
Sbjct: 5443 RFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQI 5502
Query: 444 RIALPCRAPHFHIDLDG-YLLKVTTKA-GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYN 501
++ + + G ++V A G+ ++++G F + G CG
Sbjct: 5503 PVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCT 5562
Query: 502 GHKRDDLIGGDGNFKFDVDDFAESWRVESN--EFC-----NRPQRKPVPELCQGTVKVKL 554
++RDD + DG D A++W V + + C P P +
Sbjct: 5563 NNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPC 5622
Query: 555 RAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGI 614
C + S F CH+ V F+ +C++D C + C+S AY C+ G+
Sbjct: 5623 PPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRGRL--EVPCQSLEAYAELCRARGV 5680
Query: 615 KVHWEPQQN--CAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVL- 671
W C T C VY CGP TC++ N+ P + GC CP + +L
Sbjct: 5681 CSDWRGATGGLCDLT-CPPTKVYKPCGPIQPATCNSRNQ-SPQLEGMAEGCFCPEDQILF 5738
Query: 672 --HKGRCIKPVLC 682
H G C++ C
Sbjct: 5739 NAHMGICVQACPC 5751
Score = 92.0 bits (227), Expect = 2e-18
Identities = 93/332 (28%), Positives = 131/332 (39%), Gaps = 79/332 (23%)
Query: 188 KCSCTGGRTQCVR--EVCPILSCPQHLS-HIPPGQCCPKCLGQRKVFDLPFGSCLFRSDV 244
+C+ GG Q R + CP CP ++ H C C Q
Sbjct: 317 QCTHAGGLPQDWRGPDFCP-QKCPNNMQYHECRSPCADTCSNQEH--------------- 360
Query: 245 YDNGSSFLYDNCTA-CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKF 303
S D+C A C C + TV+ D GQ GC P C +
Sbjct: 361 ----SRACEDHCVAGCFCPEGTVLD----------DIGQTGCV--------PVSKCACVY 398
Query: 304 GNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGV 363
+ G +S+ +CT C C GR C+ C PG
Sbjct: 399 NGAAYAPGATYST-DCTNCTCSGGRWSCQEVPC------------------------PGT 433
Query: 364 CTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARR---TRSFSWTKS 420
C+V G H++TFDG+ + G C YVLTK C S S F VL + RR T S + KS
Sbjct: 434 CSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDS--SAFTVLA--ELRRCGLTDSETCLKS 489
Query: 421 VELVL--GESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDG-YLLKVTTKAGLEISWDG 477
V L L ++ V ++ V N LP A + I + + T GL+++
Sbjct: 490 VTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQL 549
Query: 478 DSFVE--VMAAPHLKGKLCGLCGNYNGHKRDD 507
++ + AP L+G+ CGLCGN+N + DD
Sbjct: 550 VPTMQLFMQLAPKLRGQTCGLCGNFNSIQADD 581
Score = 57.8 bits (138), Expect = 3e-08
Identities = 84/310 (27%), Positives = 107/310 (34%), Gaps = 82/310 (26%)
Query: 84 CPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGV 143
CP D L G C + C +G +W S + CV C EG V+
Sbjct: 5731 CP---EDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCV---CDEGSVS---- 5780
Query: 144 RCVVHCKN-PLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREV 202
V CK P + G P C F V E C + C V
Sbjct: 5781 ---VQCKPLPCDAQGQP-PPCNRPGFVTVTRPRAEN-----PCCPETVC----------V 5821
Query: 203 CPILSCPQHLSHIPPGQ----------CCP--KCLGQRKVFDLPFGSCLFRSDVYDNGSS 250
C +CPQ L PPGQ CCP +C Q C + Y G++
Sbjct: 5822 CNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQ---------LCSYNGTFYGVGAT 5872
Query: 251 FLYD-NCTACTC-----RDSTVVCKRKCSHPGGCDQGQE------GCCEECLLR--VPPE 296
F C CTC +D TV C+ + C QG E CC EC+ + P+
Sbjct: 5873 FPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPD 5932
Query: 297 DIKVCKFGNKIFQDGEMWSSI---NCTICAC-VKGRTECRNKQ---CIPISSCPQGKILN 349
V Q E W + NCT+ C +G Q C +SSC L
Sbjct: 5933 GQPV--------QLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGS--LR 5982
Query: 350 RKGCCPICTE 359
+ GCC C E
Sbjct: 5983 KTGCCYSCEE 5992
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/144 (23%), Positives = 54/144 (37%), Gaps = 15/144 (10%)
Query: 69 MCVCLNKEV-TCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEP 127
+C C + ++ +C SR C A G + +G + ++ ++ P
Sbjct: 295 LCFCEDTDLLSCVCHTLAEYSRQCTHA----GGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 128 CVLRQCQEGVVTESGVRCVVHCKNP----LEHLGM--CCPTCP-GCVFEGVQYQEGEEFQ 180
C + CV C P L+ +G C P CV+ G Y G +
Sbjct: 351 CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYS 410
Query: 181 PEGSKCTKCSCTGGRTQCVREVCP 204
+ CT C+C+GGR C CP
Sbjct: 411 TD---CTNCTCSGGRWSCQEVPCP 431
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/173 (26%), Positives = 58/173 (33%), Gaps = 32/173 (18%)
Query: 62 ITDNPCIMCVCLNKEVTCKREKCPVL---SRDCALAIKQ--RGACCEQCKGCTYEGNTYN 116
+ D+ + C C C SR CA A Q C E C T
Sbjct: 933 LVDSTAYLAACAQDLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCP------RTCP 986
Query: 117 SSFKWQSPAEPCVLR------------QCQEGVVTESGVRCVVHCKNPLEHLGMCCPT-- 162
+ + Q PC C +G G C V + + H G C P
Sbjct: 987 LNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTV--LDDITHSG-CLPLGQ 1043
Query: 163 CPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHI 215
CP C G Y G F + C+ C+C+GG QC CP Q +HI
Sbjct: 1044 CP-CTHGGRTYSPGTSFN---TTCSSCTCSGGLWQCQDLPCPGTCSVQGGAHI 1092
Score = 34.3 bits (77), Expect = 0.39
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 10/67 (14%)
Query: 626 ATQCKHGAVYDTC--------GPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLH-KGRC 676
+T C VY C G C+++C ++G + CV+GC CP LV G C
Sbjct: 1450 STGCAAPMVYLDCSNSSAGTPGAECLRSCHTL-DVGCFSTHCVSGCVCPPGLVSDGSGGC 1508
Query: 677 IKPVLCP 683
I CP
Sbjct: 1509 IAEEDCP 1515
Score = 32.7 bits (73), Expect = 1.1
Identities = 21/85 (24%), Positives = 27/85 (31%), Gaps = 24/85 (28%)
Query: 142 GVRCVVHCKNPLEH-------LGMCCPTCP-----------------GCVFEGVQYQEGE 177
G C+ C+NP H L C P CP GC + Y +
Sbjct: 1865 GAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVG 1924
Query: 178 EFQPEGSKCTKCSCTGGRTQCVREV 202
P C C+CT QC +
Sbjct: 1925 ARVPTAENCQSCNCTPSGIQCAHSL 1949
Score = 32.3 bits (72), Expect = 1.5
Identities = 40/166 (24%), Positives = 56/166 (33%), Gaps = 43/166 (25%)
Query: 126 EPCVLRQCQEGVVTESGVRCVVHCK------NPLEHLGMCCP-----TCP-GCVFEGVQY 173
E CV C +SG C C G+C TCP C F
Sbjct: 1800 EACVNDAC----ACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHG 1855
Query: 174 QEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQ--CCPKCLGQRKVF 231
+QP G+ C K +C C+ ++ PG C PKC + F
Sbjct: 1856 GCEWHYQPCGAPCLK-TCRNPSGHCLVDL--------------PGLEGCYPKCPPSQPFF 1900
Query: 232 DLPFGSCLFRSDVYDNGSSFLYD---------NCTACTCRDSTVVC 268
+ C+ + YD ++ YD NC +C C S + C
Sbjct: 1901 NEDQMKCVAQCGCYDKDGNY-YDVGARVPTAENCQSCNCTPSGIQC 1945
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 157 bits (397), Expect = 3e-38
Identities = 165/633 (26%), Positives = 243/633 (38%), Gaps = 116/633 (18%)
Query: 72 CLNKEVTCKREK---CPVLS---RDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125
C+ C+R + C LS CA Q G + CT T S +
Sbjct: 657 CMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGV--CTKPMTTCPKSMTYHYHV 714
Query: 126 EPC--VLRQCQEGVVTES-GVRCVVHCKNP----LEHLGMC--CPTCPGCVFEGVQYQEG 176
C R EG +T S G V C P L+ G C CP C G G
Sbjct: 715 STCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCP-CYHRGSMIPNG 773
Query: 177 EEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFG 236
E G+ CT CT G+ C+ P P C FD
Sbjct: 774 ESVHDSGAICT---CTHGKLSCIGGQAP----------------APVCAAPMVFFD---- 810
Query: 237 SCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQG-QEGCCEECLLRVPP 295
CR++T PG G Q+ C + P
Sbjct: 811 ------------------------CRNAT---------PGDTGAGCQKSCHTLDMTCYSP 837
Query: 296 EDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPI--SSCPQGKILNRKGC 353
+ + C + + DGE I C CV R Q I + ++C + R
Sbjct: 838 QCVPGCVCPDGLVADGE-GGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWR--- 893
Query: 354 CPICTEKP--GVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKD-CS---SPASPFQVLVKN 407
CT+ P C V+GD HY TFDG++++F G C+Y L ++ C S F+V+ +N
Sbjct: 894 ---CTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTEN 950
Query: 408 DARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTT 467
T + +K++++ LG + L H V G+ + + + I G L V T
Sbjct: 951 VPCGTTGTTCSKAIKIFLGGFELKLS-HGKVEVIGTDES---QEVPYTIRQMGIYLVVDT 1006
Query: 468 KAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527
GL + WD + + + +P KG++CGLCGN++ +D + DV +F SW+
Sbjct: 1007 DIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK 1066
Query: 528 VESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTD 587
+ + C P + C K A ++C L F CH+ V+ A +Y +CV D
Sbjct: 1067 LSPS--C--PDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVND 1122
Query: 588 MCECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC--------AATQCKHGAVYDT 637
C C + C+C + AY +AC G+ V W C QC+ Y
Sbjct: 1123 ACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWH--YQP 1180
Query: 638 CGPGCIKTCDNWNEIGPCNKPC--VAGCH--CP 666
CG C++TC N G C + + GC+ CP
Sbjct: 1181 CGVPCLRTCR--NPRGDCLRDVWGLEGCYPKCP 1211
Score = 139 bits (350), Expect = 9e-33
Identities = 138/518 (26%), Positives = 205/518 (39%), Gaps = 94/518 (18%)
Query: 188 KCSCTGGRTQCVR--EVCPILSCPQHLS-HIPPGQCCPKCLGQRKVFDLPFGSCLFRSDV 244
+C+ GG Q R + CP CP ++ H C C Q
Sbjct: 317 QCTHAGGLPQDWRGPDFCP-QKCPNNMQYHECRSPCADTCSNQEH--------------- 360
Query: 245 YDNGSSFLYDNCTA-CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKF 303
S D+C A C C + TV+ D GQ GC P C +
Sbjct: 361 ----SRACEDHCVAGCFCPEGTVLD----------DIGQTGCV--------PVSKCACVY 398
Query: 304 GNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGV 363
+ G +S+ +CT C C GR C+ C PG
Sbjct: 399 NGAAYAPGATYST-DCTNCTCSGGRWSCQEVPC------------------------PGT 433
Query: 364 CTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARR---TRSFSWTKS 420
C+V G H++TFDG+ + G C YVLTK C S S F VL + RR T S + KS
Sbjct: 434 CSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDS--SAFTVLA--ELRRCGLTDSETCLKS 489
Query: 421 VELVLG--ESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDG-YLLKVTTKAGLEISWDG 477
V L L ++ V ++ V N LP A + I + + T GL+++
Sbjct: 490 VTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQL 549
Query: 478 DSFVE--VMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535
++ + AP L+G+ CGLCGN+N + DD G + F +++ ++ C
Sbjct: 550 VPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQA--ACP 607
Query: 536 RPQRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPV 593
R + C +V+ + A C +L + F CH+ V T+Y +C+ D C C
Sbjct: 608 N-IRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCER 666
Query: 594 HKNCYCESFLAYTRACQREGIK-------VHWEPQQNCAATQCKHGAVYDTCGPGCIKTC 646
++C C + +Y AC +G++ V +P C + H V TC P C
Sbjct: 667 SEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHV-STCQPTCRSLS 725
Query: 647 DNWNEIGPCNKPCVAGCHCPANLVL-HKGRCIKPVLCP 683
+ P V GC CP L G+C++ CP
Sbjct: 726 EGDITCSVGFIP-VDGCICPKGTFLDDTGKCVQASNCP 762
Score = 120 bits (301), Expect = 4e-27
Identities = 88/315 (27%), Positives = 130/315 (41%), Gaps = 20/315 (6%)
Query: 363 VCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVE 422
VC+ +G HY TFDG F F G C YV ++ C + F + ++ R S + T S
Sbjct: 80 VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLR---RSQESAAPTLSRV 136
Query: 423 LVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVE 482
L+ + V +V NG + LP I KV + GL + W+ D +
Sbjct: 137 LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLL 196
Query: 483 VMAAPHLKGKLCGLCGNYNGHK-RDDLIGGDGNFKFDVDDFAESWRVES-NEFCNRPQRK 540
+ K CGLCG++NG +L+ N K +F +++ E C P +
Sbjct: 197 LELDTKYANKTCGLCGDFNGMPVVSELL--SHNTKLTPMEFGNLQKMDDPTEQCQDPVPE 254
Query: 541 PVPELCQGTVKVKLRAHRECQKLKSWE-FQTCHSTVDYATFYRSCVTDMCECPVHK--NC 597
P P C + C++L + F C + VD ++ +C D+C C +C
Sbjct: 255 P-PRNCSTGFGI-------CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306
Query: 598 YCESFLAYTRACQRE-GIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCN 656
C + Y+R C G+ W C +C + Y C C TC N C
Sbjct: 307 VCHTLAEYSRQCTHAGGLPQDWRGPDFC-PQKCPNNMQYHECRSPCADTCSNQEHSRACE 365
Query: 657 KPCVAGCHCPANLVL 671
CVAGC CP VL
Sbjct: 366 DHCVAGCFCPEGTVL 380
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/144 (23%), Positives = 54/144 (37%), Gaps = 15/144 (10%)
Query: 69 MCVCLNKEV-TCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEP 127
+C C + ++ +C SR C A G + +G + ++ ++ P
Sbjct: 295 LCFCEDTDLLSCVCHTLAEYSRQCTHA----GGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 128 CVLRQCQEGVVTESGVRCVVHCKNP----LEHLGM--CCPTCP-GCVFEGVQYQEGEEFQ 180
C + CV C P L+ +G C P CV+ G Y G +
Sbjct: 351 CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYS 410
Query: 181 PEGSKCTKCSCTGGRTQCVREVCP 204
+ CT C+C+GGR C CP
Sbjct: 411 TD---CTNCTCSGGRWSCQEVPCP 431
Score = 36.6 bits (83), Expect = 0.079
Identities = 27/70 (38%), Positives = 32/70 (45%), Gaps = 9/70 (12%)
Query: 620 PQQNCAATQ----CKHGAVYDTCGPGCIKTCDNWNEIGPCNKP-CVAGCHCPANLVLH-K 673
P CAA C++ DT G GC K+C + C P CV GC CP LV +
Sbjct: 798 PAPVCAAPMVFFDCRNATPGDT-GAGCQKSCHTLDMT--CYSPQCVPGCVCPDGLVADGE 854
Query: 674 GRCIKPVLCP 683
G CI CP
Sbjct: 855 GGCITAEDCP 864
Score = 32.3 bits (72), Expect = 1.5
Identities = 53/225 (23%), Positives = 74/225 (32%), Gaps = 60/225 (26%)
Query: 87 LSRDCALAIKQRGACC----------EQCKGCTYEGNTYNSSFKWQSPA---EPCVLRQC 133
LS C A+ + C +QC G T+ + PA E CV C
Sbjct: 1067 LSPSCPDALAPKDPCTANPFRKSWAQKQCS--ILHGPTFAACHAHVEPARYYEACVNDAC 1124
Query: 134 QEGVVTESGVRCVVHCK------NPLEHLGMCCP-----TCP-GCVFEGVQYQEGEEFQP 181
+SG C C +G+C CP C + + Q +QP
Sbjct: 1125 ----ACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQP 1180
Query: 182 EGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFD--------- 232
G C + +C R C+R+V + C PKC + +FD
Sbjct: 1181 CGVPCLR-TCRNPRGDCLRDVWGLEGC------------YPKCPPEAPIFDEDKMQCVAT 1227
Query: 233 -----LPFGSCLFRSDVYDNGSSFLYD-NCTACTCRDSTVVCKRK 271
LP C Y G+ D NC +C C + V C K
Sbjct: 1228 CPTPPLP-PRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYK 1271
Score = 32.0 bits (71), Expect = 2.0
Identities = 34/120 (28%), Positives = 49/120 (40%), Gaps = 21/120 (17%)
Query: 266 VVCKRKCSHP-GGCDQ---GQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI 321
V C R C +P G C + G EGC +C PPE IF + +M C
Sbjct: 1183 VPCLRTCRNPRGDCLRDVWGLEGCYPKC----PPEA--------PIFDEDKMQCVATCPT 1230
Query: 322 CACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFN 381
+ R K P + P K N + C +CTE+ CT + T++G+ F+
Sbjct: 1231 PP-LPPRCHVHGKSYRPGAVVPSDK--NCQSC--LCTERGVECTYKAEACVCTYNGQRFH 1285
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 155 bits (392), Expect = 1e-37
Identities = 133/560 (23%), Positives = 222/560 (39%), Gaps = 77/560 (13%)
Query: 133 CQEGVVTESGVR-CVVHCKNPLEHLGMCCPT---CPGCVFEGVQYQEGEEFQPEGSKCTK 188
C G+V + V+ C C++ E C GC YQ E C
Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNE------GNCVL 1171
Query: 189 CSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPK--CLGQRKVFDLPFGSCLFRSDVYD 246
++QC + + P L HI +C + L + DL +C ++ D
Sbjct: 1172 ------KSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVD 1225
Query: 247 NGSSFLYDNCT-ACTCR-----DSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKV 300
C+ R D + CKR C P G + +G C V P D
Sbjct: 1226 CSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGIC------VFPNDCP- 1278
Query: 301 CKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEK 360
C FG + + +G + +S+ C C C+KG C +C I
Sbjct: 1279 CSFGGREYDEGSV-TSVGCNECTCIKGSWSCTQNECQTI--------------------- 1316
Query: 361 PGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKD-CSSPASPFQVLVKNDARRTRSFSWTK 419
C ++G+ H TFDG++++F G CQY +D C F++L ++ + ++
Sbjct: 1317 ---CHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCSR 1373
Query: 420 SVELVLGESRVSLQQ-HLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGD 478
+ + + + LQ +T + A + I G L + + G+ + WD +
Sbjct: 1374 KIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKN 1433
Query: 479 SFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQ 538
+ + V+ P+ GK+CGLCGN NG +DD + +F SW+ +++ C+
Sbjct: 1434 TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK--TSQECSDTV 1491
Query: 539 RKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNC- 597
+ P C K A R+C+ L+ F+ CH+ VD + ++ C+ + C C +
Sbjct: 1492 AQTFP--CDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYL 1549
Query: 598 -YCESFLAYTRACQREGIKVHWEPQQNC--------AATQCKHGAVYDTCGPGCIKTCDN 648
+C + Y AC G+ V W C A +C+ Y+ CG KTC +
Sbjct: 1550 GFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWH--YEPCGTVTAKTCKD 1607
Query: 649 WNEIGPCNKPCVAGCH--CP 666
+G + GC+ CP
Sbjct: 1608 -QLVGQKFSSLLEGCYAKCP 1626
Score = 73.9 bits (180), Expect = 4e-13
Identities = 100/461 (21%), Positives = 157/461 (34%), Gaps = 121/461 (26%)
Query: 268 CKRKCSHPGGC---DQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICAC 324
C C+ P G D G++G +C+L+ C+ ++Q GE+ + C C
Sbjct: 790 CVSGCTCPEGYLLDDIGEKG---KCVLKAECP----CESSGTVYQPGEVREGPCGSQCTC 842
Query: 325 VKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQG 384
+ C C PG C V G TFDG +NF G
Sbjct: 843 QDAKWSCTEALC------------------------PGRCKVEGSS-LTTFDGVKYNFPG 877
Query: 385 TCQYV-----------------------------LTKDCSSPASPF----QVLVKNDARR 411
C ++ L + S P + V ND R
Sbjct: 878 NCHFLAVHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIR 937
Query: 412 TRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGL 471
+ + ++ +++ S +L V +FH+ L +++ L
Sbjct: 938 NQGYYYSDKIQIFNASS-----SYLQVE------------TYFHVKLQ---IQIVPVMQL 977
Query: 472 EISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESN 531
+S + F + + GLCG+YN DD + + FA SW + S
Sbjct: 978 YVSMPPNQFTDTV----------GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS- 1026
Query: 532 EFCNRPQRKPVPELCQGTVKVKLRAHRECQKL--KSWEFQTCHSTVDYATFYRSCVTDMC 589
C K P C K K A R C L S +CH V+ ++ C C
Sbjct: 1027 --C----PKGNPSSCISIEKEKF-AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTC 1079
Query: 590 ECPVHKNCYCESFLAYTRAC-QREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDN 648
C ++C C Y +AC ++E V W + C G V+ C +C +
Sbjct: 1080 TCENSQDCLCTILGNYVKACAEKETYIVGW--RTGLCEHSCPSGLVFKYNVKACNSSCRS 1137
Query: 649 WNEIGPCNKPC------VAGCHCP-ANLVLHKGRCIKPVLC 682
+E ++ C V GC CP A ++G C+ C
Sbjct: 1138 LSE---RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQC 1175
Score = 57.4 bits (137), Expect = 4e-08
Identities = 35/136 (25%), Positives = 57/136 (41%), Gaps = 14/136 (10%)
Query: 558 RECQKLKSWEFQTCHSTVDYATFYRS-CVTDMCECPVHKNCYCESFLAYTRACQREGIKV 616
+ C K+ F+ C + Y+ C+ + C+ K C+++ +R C +G
Sbjct: 687 QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGT 745
Query: 617 H--WEPQQN--CAATQCKHGAVYDTCGPGCIKTCDNWNEIGPC-NKPCVAGCHCPANLVL 671
W + C +C +Y CGP TC N + P + CV+GC CP +L
Sbjct: 746 FESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSN---VAPFQDSECVSGCTCPEGYLL 802
Query: 672 ----HKGRCIKPVLCP 683
KG+C+ CP
Sbjct: 803 DDIGEKGKCVLKAECP 818
Score = 32.7 bits (73), Expect = 1.1
Identities = 12/40 (30%), Positives = 20/40 (50%)
Query: 372 YNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARR 411
Y +F+GR F F+ +C Y + C F + +K + R
Sbjct: 616 YKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNNDR 655
Score = 30.8 bits (68), Expect = 4.3
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 14/70 (20%)
Query: 145 CVVHCKNPLEHL-------GMCC--PTCPGCVFEGVQYQEGEEFQ-PEGSKCTKCSCTGG 194
CV C P +L G C CP C G YQ GE + P GS+CT C
Sbjct: 790 CVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPCGSQCT---CQDA 845
Query: 195 RTQCVREVCP 204
+ C +CP
Sbjct: 846 KWSCTEALCP 855
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 155 bits (392), Expect = 1e-37
Identities = 133/560 (23%), Positives = 222/560 (39%), Gaps = 77/560 (13%)
Query: 133 CQEGVVTESGVR-CVVHCKNPLEHLGMCCPT---CPGCVFEGVQYQEGEEFQPEGSKCTK 188
C G+V + V+ C C++ E C GC YQ E C
Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNE------GNCVL 1171
Query: 189 CSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPK--CLGQRKVFDLPFGSCLFRSDVYD 246
++QC + + P L HI +C + L + DL +C ++ D
Sbjct: 1172 ------KSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVD 1225
Query: 247 NGSSFLYDNCT-ACTCR-----DSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKV 300
C+ R D + CKR C P G + +G C V P D
Sbjct: 1226 CSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGIC------VFPNDCP- 1278
Query: 301 CKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEK 360
C FG + + +G + +S+ C C C+KG C +C I
Sbjct: 1279 CSFGGREYDEGSV-TSVGCNECTCIKGSWSCTQNECQTI--------------------- 1316
Query: 361 PGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKD-CSSPASPFQVLVKNDARRTRSFSWTK 419
C ++G+ H TFDG++++F G CQY +D C F++L ++ + ++
Sbjct: 1317 ---CHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCSR 1373
Query: 420 SVELVLGESRVSLQQ-HLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGD 478
+ + + + LQ +T + A + I G L + + G+ + WD +
Sbjct: 1374 KIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKN 1433
Query: 479 SFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQ 538
+ + V+ P+ GK+CGLCGN NG +DD + +F SW+ +++ C+
Sbjct: 1434 TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK--TSQECSDTV 1491
Query: 539 RKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNC- 597
+ P C K A R+C+ L+ F+ CH+ VD + ++ C+ + C C +
Sbjct: 1492 AQTFP--CDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYL 1549
Query: 598 -YCESFLAYTRACQREGIKVHWEPQQNC--------AATQCKHGAVYDTCGPGCIKTCDN 648
+C + Y AC G+ V W C A +C+ Y+ CG KTC +
Sbjct: 1550 GFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWH--YEPCGTVTAKTCKD 1607
Query: 649 WNEIGPCNKPCVAGCH--CP 666
+G + GC+ CP
Sbjct: 1608 -QLVGQKFSSLLEGCYAKCP 1626
Score = 73.9 bits (180), Expect = 4e-13
Identities = 100/461 (21%), Positives = 157/461 (34%), Gaps = 121/461 (26%)
Query: 268 CKRKCSHPGGC---DQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICAC 324
C C+ P G D G++G +C+L+ C+ ++Q GE+ + C C
Sbjct: 790 CVSGCTCPEGYLLDDIGEKG---KCVLKAECP----CESSGTVYQPGEVREGPCGSQCTC 842
Query: 325 VKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQG 384
+ C C PG C V G TFDG +NF G
Sbjct: 843 QDAKWSCTEALC------------------------PGRCKVEGSS-LTTFDGVKYNFPG 877
Query: 385 TCQYV-----------------------------LTKDCSSPASPF----QVLVKNDARR 411
C ++ L + S P + V ND R
Sbjct: 878 NCHFLAVHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIR 937
Query: 412 TRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGL 471
+ + ++ +++ S +L V +FH+ L +++ L
Sbjct: 938 NQGYYYSDKIQIFNASS-----SYLQVE------------TYFHVKLQ---IQIVPVMQL 977
Query: 472 EISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESN 531
+S + F + + GLCG+YN DD + + FA SW + S
Sbjct: 978 YVSMPPNQFTDTV----------GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS- 1026
Query: 532 EFCNRPQRKPVPELCQGTVKVKLRAHRECQKL--KSWEFQTCHSTVDYATFYRSCVTDMC 589
C K P C K K A R C L S +CH V+ ++ C C
Sbjct: 1027 --C----PKGNPSSCISIEKEKF-AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTC 1079
Query: 590 ECPVHKNCYCESFLAYTRAC-QREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDN 648
C ++C C Y +AC ++E V W + C G V+ C +C +
Sbjct: 1080 TCENSQDCLCTILGNYVKACAEKETYIVGW--RTGLCEHSCPSGLVFKYNVKACNSSCRS 1137
Query: 649 WNEIGPCNKPC------VAGCHCP-ANLVLHKGRCIKPVLC 682
+E ++ C V GC CP A ++G C+ C
Sbjct: 1138 LSE---RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQC 1175
Score = 57.8 bits (138), Expect = 3e-08
Identities = 35/136 (25%), Positives = 57/136 (41%), Gaps = 14/136 (10%)
Query: 558 RECQKLKSWEFQTCHSTVDYATFYRS-CVTDMCECPVHKNCYCESFLAYTRACQREGIKV 616
+ C K+ F+ C + Y+ C+ + C+ K C+++ +R C +G
Sbjct: 687 QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGT 745
Query: 617 H--WEPQQN--CAATQCKHGAVYDTCGPGCIKTCDNWNEIGPC-NKPCVAGCHCPANLVL 671
W + C +C +Y CGP TC N + P + CV+GC CP +L
Sbjct: 746 FESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSN---VAPFQDSECVSGCTCPEGYLL 802
Query: 672 ----HKGRCIKPVLCP 683
KG+C+ CP
Sbjct: 803 DDIGEKGKCVLKAECP 818
Score = 32.7 bits (73), Expect = 1.1
Identities = 12/40 (30%), Positives = 20/40 (50%)
Query: 372 YNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARR 411
Y +F+GR F F+ +C Y + C F + +K + R
Sbjct: 616 YKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNNDR 655
Score = 30.8 bits (68), Expect = 4.3
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 14/70 (20%)
Query: 145 CVVHCKNPLEHL-------GMCC--PTCPGCVFEGVQYQEGEEFQ-PEGSKCTKCSCTGG 194
CV C P +L G C CP C G YQ GE + P GS+CT C
Sbjct: 790 CVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPCGSQCT---CQDA 845
Query: 195 RTQCVREVCP 204
+ C +CP
Sbjct: 846 KWSCTEALCP 855
>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
Length = 814
Score = 154 bits (390), Expect = 2e-37
Identities = 122/405 (30%), Positives = 163/405 (40%), Gaps = 100/405 (24%)
Query: 16 RRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNK 75
R PG TCC + C G FL G + GE P + +PC C C N
Sbjct: 297 RPLPG-TCCPV----CDGC-------FLNG---REHRSGE----PVGSGDPCSHCRCANG 337
Query: 76 EVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNS--SFKWQSPAEPCVLRQC 133
V C+ CP + C K G CC C GC Y+G+ Y S +F+ Q CV C
Sbjct: 338 SVQCEPLPCPPVP--CRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGL-CVRCSC 394
Query: 134 QEGVVTESGVRC-VVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCT 192
Q G V+ C V C P +C P C +G ++ EG +++P+G CT C C
Sbjct: 395 QAGEVSCEEQECPVTPCALPASGRQLC----PACELDGEEFAEGVQWEPDGRPCTACVCQ 450
Query: 193 GGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFL 252
G +C +CP C QH + PPG CCP C SC + S VY NG +F
Sbjct: 451 DGVPKCGAVLCPPAPC-QHPTQ-PPGACCPSC-----------DSCTYHSQVYANGQNFT 497
Query: 253 YDN--CTACTCRDSTVVCKRKCSHPGGCDQGQEG---C---CEECLL------------- 291
+ C AC C+D TV C P C + Q G C C +C+L
Sbjct: 498 DADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSH 557
Query: 292 -----------------------RVP----------PEDIKVCKFGNKIFQDGEMW--SS 316
R P P D C FG K + G + S
Sbjct: 558 PRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPS 617
Query: 317 INCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKP 361
C +C C+ G +C ++C+P+ CP+ +L + CCP C P
Sbjct: 618 DPCRLCRCLSGNVQCLARRCVPL-PCPEPVLLPGE-CCPQCPAAP 660
Score = 152 bits (383), Expect = 1e-36
Identities = 95/318 (29%), Positives = 133/318 (41%), Gaps = 39/318 (12%)
Query: 50 CENEGEVLQ--IPFITD-NPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK 106
C+ EG++ + + F++ NPC+ C CL V C KCP C + + G CC C+
Sbjct: 192 CDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKCP--PSPCPEPVLRPGHCCPTCQ 249
Query: 107 GCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHL-GMCCPTCPG 165
GCT G+ + +W +P +PC + +C EG + C C P L G CCP C G
Sbjct: 250 GCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG 309
Query: 166 CVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCL 225
C G +++ GE G C+ C C G QC CP + C +H I PGQCCP C
Sbjct: 310 CFLNGREHRSGEPV-GSGDPCSHCRCANGSVQCEPLPCPPVPC-RHPGKI-PGQCCPVCD 366
Query: 226 GQRKVFDLPFGSCLFRSDVYDNGSSFLYDN---CTACTCRDSTVVCKRKCSHPGGCDQGQ 282
G C ++ Y + +F C C+C+ V C+ Q
Sbjct: 367 G-----------CEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEE-----------Q 404
Query: 283 EGCCEECLLRVPPEDI-KVCKFGNKIFQDGEMWSSIN--CTICACVKGRTECRNKQCIPI 339
E C L + C+ + F +G W CT C C G +C C P
Sbjct: 405 ECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLC-PP 463
Query: 340 SSCPQGKILNRKGCCPIC 357
+ C Q CCP C
Sbjct: 464 APC-QHPTQPPGACCPSC 480
Score = 150 bits (380), Expect = 3e-36
Identities = 96/300 (32%), Positives = 124/300 (41%), Gaps = 28/300 (9%)
Query: 64 DNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQS 123
D+PC C C + VTC CP + CA G CC +C C E + +
Sbjct: 500 DSPCHACHCQDGTVTCSLVDCPPTT--CARPQSGPGQCCPRCPDCILEEEVFVDGESFSH 557
Query: 124 PAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPT-CPGCVFEGVQYQEGEEFQP 181
P +PC +CQEG C C +PL G CCP C GC F G +Y G +F
Sbjct: 558 PRDPCQECRCQEGHAHCQPRPCPRAPCAHPLP--GTCCPNDCSGCAFGGKEYPSGADFPH 615
Query: 182 EGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPF-GSCLF 240
C C C G QC+ C L CP+ + + PG+CCP+C P G+
Sbjct: 616 PSDPCRLCRCLSGNVQCLARRCVPLPCPEPV--LLPGECCPQCPAAPAPAGCPRPGAAHA 673
Query: 241 RSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEG-CCEECLLRVPPEDIK 299
R Y + D C C C D +V C+R P C ++G CC C
Sbjct: 674 RHQEYFSPPG---DPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSC---------D 721
Query: 300 VCKFGNKIFQDGEMWSSIN--CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
C + K F GE + S C +C C +G C K C P + CP R CCP C
Sbjct: 722 GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP-ALCP---FPARGDCCPDC 777
Score = 137 bits (344), Expect = 4e-32
Identities = 92/318 (28%), Positives = 118/318 (37%), Gaps = 31/318 (9%)
Query: 50 CENEGEVLQ--IPFITDN-PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK 106
CE +GE + + D PC CVC + C CP C + GACC C
Sbjct: 424 CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCP--PAPCQHPTQPPGACCPSCD 481
Query: 107 GCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPTCPG 165
CTY Y + + PC CQ+G VT S V C C P G CCP CP
Sbjct: 482 SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPD 541
Query: 166 CVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPK-C 224
C+ E + +GE F C +C C G C CP C +H PG CCP C
Sbjct: 542 CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPC----AHPLPGTCCPNDC 597
Query: 225 LGQRKVFDLPFGSCLFRSDVYDNGSSFLY--DNCTACTCRDSTVVCKRKCSHPGGCDQG- 281
G C F Y +G+ F + D C C C V C + P C +
Sbjct: 598 SG-----------CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 646
Query: 282 --QEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPI 339
CC +C P + Q+ C C C+ G C+ C P
Sbjct: 647 LLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC-PP 705
Query: 340 SSCPQGKILNRKGCCPIC 357
+ C + + CCP C
Sbjct: 706 APCAHPR---QGPCCPSC 720
Score = 132 bits (333), Expect = 8e-31
Identities = 89/303 (29%), Positives = 122/303 (40%), Gaps = 46/303 (15%)
Query: 67 CIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK-GCTYEGNTYNSSFKWQSPA 125
C C CL +TC ++ CP C + GACC CK GC YEG Y + S +
Sbjct: 156 CTTCRCLEGTITCNQKPCP--RGPCP----EPGACCPHCKPGCDYEGQLYEEGVTFLSSS 209
Query: 126 EPCVLRQCQEGVVTESGVRCVVH-CKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGS 184
PC+ C V ++C C P+ G CCPTC GC G ++ G+E+ G
Sbjct: 210 NPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGD 269
Query: 185 KCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDV 244
C C C G QC + C L CP + PG CCP C G C
Sbjct: 270 PCRICRCLEGHIQCRQRECASL-CPYPARPL-PGTCCPVCDG-----------CFLNGRE 316
Query: 245 YDNGSSF-LYDNCTACTCRDSTVVCKR------KCSHPGGCDQGQEGCCEECLLRVPPED 297
+ +G D C+ C C + +V C+ C HPG GQ CC C
Sbjct: 317 HRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKI-PGQ--CCPVC-------- 365
Query: 298 IKVCKFGNKIFQDGEMWSSIN---CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354
C++ +Q E + C C+C G C ++C P++ C + + C
Sbjct: 366 -DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQEC-PVTPC--ALPASGRQLC 421
Query: 355 PIC 357
P C
Sbjct: 422 PAC 424
Score = 122 bits (306), Expect = 1e-27
Identities = 81/283 (28%), Positives = 118/283 (41%), Gaps = 47/283 (16%)
Query: 91 CALAIKQRGA--CCEQ-----CKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGV 143
C + Q GA C Q C+GC+ G TY + + A C +C EG +T +
Sbjct: 114 CTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDA--CTTCRCLEGTITCNQK 171
Query: 144 RCVVHCKNPLEHLGMCCPTC-PGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREV 202
C + P G CCP C PGC +EG Y+EG F + C +C+C R +C+
Sbjct: 172 PCP---RGPCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALK 228
Query: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLY--DNCTACT 260
CP CP+ + + PG CCP C G C +++G + D C C
Sbjct: 229 CPPSPCPEPV--LRPGHCCPTCQG-----------CTEGGSHWEHGQEWTTPGDPCRICR 275
Query: 261 CRDSTVVCKRK-----CSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGE-MW 314
C + + C+++ C +P G CC C C + + GE +
Sbjct: 276 CLEGHIQCRQRECASLCPYPARPLPGT--CCPVC---------DGCFLNGREHRSGEPVG 324
Query: 315 SSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
S C+ C C G +C C P+ GKI + CCP+C
Sbjct: 325 SGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQ--CCPVC 365
Score = 92.8 bits (229), Expect = 9e-19
Identities = 53/171 (30%), Positives = 76/171 (44%), Gaps = 16/171 (9%)
Query: 65 NPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK------GCTYEGNTYNSS 118
+PC +C CL+ V C +C L C + G CC QC GC G +
Sbjct: 618 DPCRLCRCLSGNVQCLARRCVPLP--CPEPVLLPGECCPQCPAAPAPAGCPRPGAAHARH 675
Query: 119 FKWQSP-AEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCCPTCPGCVFEGVQYQEG 176
++ SP +PC C +G V+ + C C +P + G CCP+C GC+++G ++ G
Sbjct: 676 QEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ--GPCCPSCDGCLYQGKEFASG 733
Query: 177 EEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQ 227
E F + C C C G C + C CP G CCP C G+
Sbjct: 734 ERFPSPTAACHLCLCWEGSVSCEPKACAPALCP----FPARGDCCPDCDGE 780
Score = 85.5 bits (210), Expect = 1e-16
Identities = 62/240 (25%), Positives = 92/240 (38%), Gaps = 51/240 (21%)
Query: 120 KWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEF 179
+W E V+ ++ ++ VR + C+ C P P C G + EG +
Sbjct: 58 EWLGRLEAAVMELREQNKDLQTRVRQLESCE--------CHPASPQCWGLGRAWPEGARW 109
Query: 180 QPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCL 239
+P+ CT C C G C + HL H C G C
Sbjct: 110 EPDA--CTACVCQDGAAHCGPQA--------HLPH---------CRG-----------CS 139
Query: 240 FRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIK 299
Y NG +F D CT C C + T+ C +K G C + CC C
Sbjct: 140 QNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCPE-PGACCPHCK--------P 190
Query: 300 VCKFGNKIFQDGEMW--SSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPIC 357
C + +++++G + SS C C C++ R C +C P S CP+ +L CCP C
Sbjct: 191 GCDYEGQLYEEGVTFLSSSNPCLQCTCLRSRVRCMALKC-PPSPCPE-PVLRPGHCCPTC 248
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 145 bits (367), Expect = 9e-35
Identities = 95/332 (28%), Positives = 142/332 (42%), Gaps = 10/332 (3%)
Query: 359 EKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSW 417
E+ +C +G H TFDG + G Y L F + V ND + S ++
Sbjct: 74 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133
Query: 418 TKSVELV-LGESRVSLQQHLTVRWNGSRIALPCRAPHFHID-LDGYLLKVTTKAGLEISW 475
+++V L +GE + L + +T G R+ LP + L GY++ V ++ ++W
Sbjct: 134 SRAVSLFFVGEQEIHLAKEVT--HGGMRVQLPHVMGSARLQQLAGYVI-VRHQSAFTLAW 190
Query: 476 DGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535
DG S V + +P L G GLCGN N +DDL+ G DV +F SW+ ++
Sbjct: 191 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPP 250
Query: 536 RPQRK--PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPV 593
P P P Q + +C+ L F CH+ V F SC +D+C+
Sbjct: 251 GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMG 310
Query: 594 HKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA-VYDTCGPGCIKTCDNWNE 651
+C + Y RAC + G + W Q CK A Y+ C C +C
Sbjct: 311 DVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRAS 370
Query: 652 IGPCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
CV GC+CP L+ G C+ P CP
Sbjct: 371 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 402
Score = 134 bits (338), Expect = 2e-31
Identities = 112/453 (24%), Positives = 174/453 (38%), Gaps = 64/453 (14%)
Query: 244 VYDNGSSFLYDNCTAC---------TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294
V+ +F Y+ C AC +C DS + C C P G GC V
Sbjct: 345 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC-------VA 397
Query: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354
P + C+F ++ G + +C C C G+ EC C
Sbjct: 398 PAECP-CEFHGTLYPPGSVVKE-DCNTCTCTSGKWECSTAVC------------------ 437
Query: 355 PICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTR 413
P C+V GD H+ TFDGR + F TCQY+L K SS F V ++N +
Sbjct: 438 ------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 489
Query: 414 SFSWTKSVELVLGES---RVSLQQHLTV-RWNGSRIALPCRAPHFHI-DLDGYLLKVTTK 468
+ +SV ++L + +V+L Q V ++ +I P F I L L+V T
Sbjct: 490 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549
Query: 469 AGLEISWDGDSF-VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527
G+ + +D + + + GLCG +NG+ +DD + G + F SW+
Sbjct: 550 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 609
Query: 528 VESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTD 587
S C+ + C ++ + + C L F C + + ++ C D
Sbjct: 610 TLS--ACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 667
Query: 588 MCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCD 647
C C + C C + Y C+R G+ V + + A C+ Y C C +TC
Sbjct: 668 ACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQ 725
Query: 648 NWNEIGPC---------NKPCVAGCHCPANLVL 671
+ C CV GC CP + L
Sbjct: 726 DLASPEACGVDGGDDLSRDECVEGCACPPDTYL 758
Score = 122 bits (305), Expect = 1e-27
Identities = 138/578 (23%), Positives = 205/578 (35%), Gaps = 104/578 (17%)
Query: 66 PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125
PC+ + C+R PV R + AC C+ +S ++
Sbjct: 674 PCLCATLAHYAHLCRRHGLPVDFR------ARLPACALSCE----------ASKEYSPCV 717
Query: 126 EPCVLRQCQEGVVTES-GV---------RCVVHCKNPLE-----HLGMCCPTCP-GCVFE 169
PC R CQ+ E+ GV CV C P + +C P C F+
Sbjct: 718 APCG-RTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 170 GVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRK 229
GV Y G+ P C C G C P +CP GQ C
Sbjct: 777 GVDYPPGDSDIPS---LGHCHCKDGVMSCDSRA-PAAACPA-------GQVFVNC----- 820
Query: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEEC 289
SD++ + C + +V + C C QG + C
Sbjct: 821 ------------SDLHTDLELSRERTCEQ-QLLNLSVSARGPCLSGCACPQGLLRHGDAC 867
Query: 290 LLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILN 349
L PE+ G + F ++ S C C C +G +C C
Sbjct: 868 FL---PEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPCA------------ 910
Query: 350 RKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDA 409
CT +GD HY TFDG F+F G C+ L K S + F V+V+N
Sbjct: 911 ------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS--FSVIVENVN 956
Query: 410 RRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVT-TK 468
+ K + + +G S + N S + H G+ V +
Sbjct: 957 CYSSGMICRKFISINVGNSLIVFDDD---SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
Query: 469 AGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV 528
+ + WD + V V A P +G+L GLCGN++ +++ + + +F SW
Sbjct: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
Query: 529 ESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDM 588
C P ++C + A +EC L S F+ CH VD FY +C+TD
Sbjct: 1074 VE---C--PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1128
Query: 589 CECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC 624
C C + C+C S AY C + G+ V W + C
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 1166
Score = 66.6 bits (161), Expect = 7e-11
Identities = 92/406 (22%), Positives = 154/406 (37%), Gaps = 71/406 (17%)
Query: 318 NCTICACVKGRTECRNKQCIPISSCPQGKILNRKG------------CCPICTEKPGVCT 365
+C C++G+ N+ CPQG R G CCP+ E C+
Sbjct: 1986 DCVRHICLEGQLIRVNQS----QHCPQGAAPPRCGILGLAVRVGGDRCCPLW-ECACRCS 2040
Query: 366 VFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTRSFSWTKSVELV 424
+F D + TFDG Y+L++ SP V V + + +W ++
Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQ---SPDEMLTVHVLDCKSANLGHLNWPPFCLVM 2097
Query: 425 LGESRVSLQQHLTVRWNGSRIAL-------PCRAPHFHIDLDGYLLKVTTKAGLEISW-D 476
L + ++ Q +T+ ++ + P F I+ G++ + T + ++I W
Sbjct: 2098 LNMTHLAHQ--VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLH 2155
Query: 477 GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD---FAESWRVESNEF 533
+ V A+ K + GLCG +G +DL DG+ +D F +SW+V S+
Sbjct: 2156 SSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSS-L 2214
Query: 534 CNRPQRKPVPELCQGTVKVKLRAHREC----QKLKSWEFQTCHSTVDYATFYRSCVTDMC 589
+ Q + P+ C T +C + + + F CH V +F C
Sbjct: 2215 TSVGQTRFRPDSCATT---------DCSPCLRMVSNRTFSACHRFVPPESF--------C 2257
Query: 590 ECPVHKNCY----CESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGC--I 643
E + Y C + Y C + + + W C C + Y C C
Sbjct: 2258 ELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL-CSSDSTYQACVTACEPP 2316
Query: 644 KTCDNWNEIGPCN-KPCVA---GCHCPANLVLHK---GRCIKPVLC 682
KTC + +GP + + C GC C +LH+ CI C
Sbjct: 2317 KTCQD-GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 12/154 (7%)
Query: 56 VLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTY 115
V +PF +C + T R +R CA A + Q + CT +
Sbjct: 292 VSPLPFTASCTSDLCQSMGDVATWCRALAEY-ARACAQAGRPLQGWRTQLRQCTV--HCK 348
Query: 116 NSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNP----LEHLGMCCPT-CPGCVFEG 170
+F + C +S + CV C P E G P CP C F G
Sbjct: 349 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP-CEFHG 407
Query: 171 VQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCP 204
Y G + + C C+CT G+ +C VCP
Sbjct: 408 TLYPPGSVVKED---CNTCTCTSGKWECSTAVCP 438
Score = 34.7 bits (78), Expect = 0.30
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 658 PCVAGCHCPANLVLHKGRCIKPVLCP 683
PC++GC CP L+ H C P CP
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECP 874
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 145 bits (367), Expect = 9e-35
Identities = 95/332 (28%), Positives = 142/332 (42%), Gaps = 10/332 (3%)
Query: 359 EKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSW 417
E+ +C +G H TFDG + G Y L F + V ND + S ++
Sbjct: 146 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 205
Query: 418 TKSVELV-LGESRVSLQQHLTVRWNGSRIALPCRAPHFHID-LDGYLLKVTTKAGLEISW 475
+++V L +GE + L + +T G R+ LP + L GY++ V ++ ++W
Sbjct: 206 SRAVSLFFVGEQEIHLAKEVT--HGGMRVQLPHVMGSARLQQLAGYVI-VRHQSAFTLAW 262
Query: 476 DGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535
DG S V + +P L G GLCGN N +DDL+ G DV +F SW+ ++
Sbjct: 263 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPP 322
Query: 536 RPQRK--PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPV 593
P P P Q + +C+ L F CH+ V F SC +D+C+
Sbjct: 323 GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMG 382
Query: 594 HKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA-VYDTCGPGCIKTCDNWNE 651
+C + Y RAC + G + W Q CK A Y+ C C +C
Sbjct: 383 DVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRAS 442
Query: 652 IGPCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
CV GC+CP L+ G C+ P CP
Sbjct: 443 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 474
Score = 134 bits (338), Expect = 2e-31
Identities = 112/453 (24%), Positives = 174/453 (38%), Gaps = 64/453 (14%)
Query: 244 VYDNGSSFLYDNCTAC---------TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294
V+ +F Y+ C AC +C DS + C C P G GC V
Sbjct: 417 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC-------VA 469
Query: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354
P + C+F ++ G + +C C C G+ EC C
Sbjct: 470 PAECP-CEFHGTLYPPGSVVKE-DCNTCTCTSGKWECSTAVC------------------ 509
Query: 355 PICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTR 413
P C+V GD H+ TFDGR + F TCQY+L K SS F V ++N +
Sbjct: 510 ------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 561
Query: 414 SFSWTKSVELVLGES---RVSLQQHLTV-RWNGSRIALPCRAPHFHI-DLDGYLLKVTTK 468
+ +SV ++L + +V+L Q V ++ +I P F I L L+V T
Sbjct: 562 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 621
Query: 469 AGLEISWDGDSF-VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527
G+ + +D + + + GLCG +NG+ +DD + G + F SW+
Sbjct: 622 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 681
Query: 528 VESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTD 587
S C+ + C ++ + + C L F C + + ++ C D
Sbjct: 682 TLS--ACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 739
Query: 588 MCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCD 647
C C + C C + Y C+R G+ V + + A C+ Y C C +TC
Sbjct: 740 ACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQ 797
Query: 648 NWNEIGPC---------NKPCVAGCHCPANLVL 671
+ C CV GC CP + L
Sbjct: 798 DLASPEACGVDGGDDLSRDECVEGCACPPDTYL 830
Score = 122 bits (305), Expect = 1e-27
Identities = 138/578 (23%), Positives = 205/578 (35%), Gaps = 104/578 (17%)
Query: 66 PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125
PC+ + C+R PV R + AC C+ +S ++
Sbjct: 746 PCLCATLAHYAHLCRRHGLPVDFR------ARLPACALSCE----------ASKEYSPCV 789
Query: 126 EPCVLRQCQEGVVTES-GV---------RCVVHCKNPLE-----HLGMCCPTCP-GCVFE 169
PC R CQ+ E+ GV CV C P + +C P C F+
Sbjct: 790 APCG-RTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 170 GVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRK 229
GV Y G+ P C C G C P +CP GQ C
Sbjct: 849 GVDYPPGDSDIPS---LGHCHCKDGVMSCDSRA-PAAACPA-------GQVFVNC----- 892
Query: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEEC 289
SD++ + C + +V + C C QG + C
Sbjct: 893 ------------SDLHTDLELSRERTCEQ-QLLNLSVSARGPCLSGCACPQGLLRHGDAC 939
Query: 290 LLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILN 349
L PE+ G + F ++ S C C C +G +C C
Sbjct: 940 FL---PEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPCA------------ 982
Query: 350 RKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDA 409
CT +GD HY TFDG F+F G C+ L K S + F V+V+N
Sbjct: 983 ------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS--FSVIVENVN 1028
Query: 410 RRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVT-TK 468
+ K + + +G S + N S + H G+ V +
Sbjct: 1029 CYSSGMICRKFISINVGNSLIVFDDD---SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085
Query: 469 AGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV 528
+ + WD + V V A P +G+L GLCGN++ +++ + + +F SW
Sbjct: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145
Query: 529 ESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDM 588
C P ++C + A +EC L S F+ CH VD FY +C+TD
Sbjct: 1146 VE---C--PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200
Query: 589 CECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC 624
C C + C+C S AY C + G+ V W + C
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 1238
Score = 66.6 bits (161), Expect = 7e-11
Identities = 92/406 (22%), Positives = 154/406 (37%), Gaps = 71/406 (17%)
Query: 318 NCTICACVKGRTECRNKQCIPISSCPQGKILNRKG------------CCPICTEKPGVCT 365
+C C++G+ N+ CPQG R G CCP+ E C+
Sbjct: 2058 DCVRHICLEGQLIRVNQS----QHCPQGAAPPRCGILGLAVRVGGDRCCPLW-ECACRCS 2112
Query: 366 VFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTRSFSWTKSVELV 424
+F D + TFDG Y+L++ SP V V + + +W ++
Sbjct: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQ---SPDEMLTVHVLDCKSANLGHLNWPPFCLVM 2169
Query: 425 LGESRVSLQQHLTVRWNGSRIAL-------PCRAPHFHIDLDGYLLKVTTKAGLEISW-D 476
L + ++ Q +T+ ++ + P F I+ G++ + T + ++I W
Sbjct: 2170 LNMTHLAHQ--VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLH 2227
Query: 477 GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD---FAESWRVESNEF 533
+ V A+ K + GLCG +G +DL DG+ +D F +SW+V S+
Sbjct: 2228 SSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSS-L 2286
Query: 534 CNRPQRKPVPELCQGTVKVKLRAHREC----QKLKSWEFQTCHSTVDYATFYRSCVTDMC 589
+ Q + P+ C T +C + + + F CH V +F C
Sbjct: 2287 TSVGQTRFRPDSCATT---------DCSPCLRMVSNRTFSACHRFVPPESF--------C 2329
Query: 590 ECPVHKNCY----CESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGC--I 643
E + Y C + Y C + + + W C C + Y C C
Sbjct: 2330 ELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL-CSSDSTYQACVTACEPP 2388
Query: 644 KTCDNWNEIGPCN-KPCVA---GCHCPANLVLHK---GRCIKPVLC 682
KTC + +GP + + C GC C +LH+ CI C
Sbjct: 2389 KTCQD-GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 12/154 (7%)
Query: 56 VLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTY 115
V +PF +C + T R +R CA A + Q + CT +
Sbjct: 364 VSPLPFTASCTSDLCQSMGDVATWCRALAEY-ARACAQAGRPLQGWRTQLRQCTV--HCK 420
Query: 116 NSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNP----LEHLGMCCPT-CPGCVFEG 170
+F + C +S + CV C P E G P CP C F G
Sbjct: 421 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP-CEFHG 479
Query: 171 VQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCP 204
Y G + + C C+CT G+ +C VCP
Sbjct: 480 TLYPPGSVVKED---CNTCTCTSGKWECSTAVCP 510
Score = 34.7 bits (78), Expect = 0.30
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 658 PCVAGCHCPANLVLHKGRCIKPVLCP 683
PC++GC CP L+ H C P CP
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECP 946
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 145 bits (367), Expect = 9e-35
Identities = 95/332 (28%), Positives = 142/332 (42%), Gaps = 10/332 (3%)
Query: 359 EKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSW 417
E+ +C +G H TFDG + G Y L F + V ND + S ++
Sbjct: 74 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133
Query: 418 TKSVELV-LGESRVSLQQHLTVRWNGSRIALPCRAPHFHID-LDGYLLKVTTKAGLEISW 475
+++V L +GE + L + +T G R+ LP + L GY++ V ++ ++W
Sbjct: 134 SRAVSLFFVGEQEIHLAKEVT--HGGMRVQLPHVMGSARLQQLAGYVI-VRHQSAFTLAW 190
Query: 476 DGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535
DG S V + +P L G GLCGN N +DDL+ G DV +F SW+ ++
Sbjct: 191 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPP 250
Query: 536 RPQRK--PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPV 593
P P P Q + +C+ L F CH+ V F SC +D+C+
Sbjct: 251 GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMG 310
Query: 594 HKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA-VYDTCGPGCIKTCDNWNE 651
+C + Y RAC + G + W Q CK A Y+ C C +C
Sbjct: 311 DVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRAS 370
Query: 652 IGPCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
CV GC+CP L+ G C+ P CP
Sbjct: 371 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 402
Score = 134 bits (338), Expect = 2e-31
Identities = 112/453 (24%), Positives = 174/453 (38%), Gaps = 64/453 (14%)
Query: 244 VYDNGSSFLYDNCTAC---------TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294
V+ +F Y+ C AC +C DS + C C P G GC V
Sbjct: 345 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC-------VA 397
Query: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354
P + C+F ++ G + +C C C G+ EC C
Sbjct: 398 PAECP-CEFHGTLYPPGSVVKE-DCNTCTCTSGKWECSTAVC------------------ 437
Query: 355 PICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTR 413
P C+V GD H+ TFDGR + F TCQY+L K SS F V ++N +
Sbjct: 438 ------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 489
Query: 414 SFSWTKSVELVLGES---RVSLQQHLTV-RWNGSRIALPCRAPHFHI-DLDGYLLKVTTK 468
+ +SV ++L + +V+L Q V ++ +I P F I L L+V T
Sbjct: 490 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549
Query: 469 AGLEISWDGDSF-VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527
G+ + +D + + + GLCG +NG+ +DD + G + F SW+
Sbjct: 550 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 609
Query: 528 VESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTD 587
S C+ + C ++ + + C L F C + + ++ C D
Sbjct: 610 TLS--ACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 667
Query: 588 MCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCD 647
C C + C C + Y C+R G+ V + + A C+ Y C C +TC
Sbjct: 668 ACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQ 725
Query: 648 NWNEIGPC---------NKPCVAGCHCPANLVL 671
+ C CV GC CP + L
Sbjct: 726 DLASPEACGVDGGDDLSRDECVEGCACPPDTYL 758
Score = 122 bits (305), Expect = 1e-27
Identities = 138/578 (23%), Positives = 205/578 (35%), Gaps = 104/578 (17%)
Query: 66 PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125
PC+ + C+R PV R + AC C+ +S ++
Sbjct: 674 PCLCATLAHYAHLCRRHGLPVDFR------ARLPACALSCE----------ASKEYSPCV 717
Query: 126 EPCVLRQCQEGVVTES-GV---------RCVVHCKNPLE-----HLGMCCPTCP-GCVFE 169
PC R CQ+ E+ GV CV C P + +C P C F+
Sbjct: 718 APCG-RTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 170 GVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRK 229
GV Y G+ P C C G C P +CP GQ C
Sbjct: 777 GVDYPPGDSDIPS---LGHCHCKDGVMSCDSRA-PAAACPA-------GQVFVNC----- 820
Query: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEEC 289
SD++ + C + +V + C C QG + C
Sbjct: 821 ------------SDLHTDLELSRERTCEQ-QLLNLSVSARGPCLSGCACPQGLLRHGDAC 867
Query: 290 LLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILN 349
L PE+ G + F ++ S C C C +G +C C
Sbjct: 868 FL---PEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPCA------------ 910
Query: 350 RKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDA 409
CT +GD HY TFDG F+F G C+ L K S + F V+V+N
Sbjct: 911 ------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS--FSVIVENVN 956
Query: 410 RRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVT-TK 468
+ K + + +G S + N S + H G+ V +
Sbjct: 957 CYSSGMICRKFISINVGNSLIVFDDD---SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
Query: 469 AGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV 528
+ + WD + V V A P +G+L GLCGN++ +++ + + +F SW
Sbjct: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
Query: 529 ESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDM 588
C P ++C + A +EC L S F+ CH VD FY +C+TD
Sbjct: 1074 VE---C--PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1128
Query: 589 CECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC 624
C C + C+C S AY C + G+ V W + C
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 1166
Score = 66.6 bits (161), Expect = 7e-11
Identities = 92/406 (22%), Positives = 154/406 (37%), Gaps = 71/406 (17%)
Query: 318 NCTICACVKGRTECRNKQCIPISSCPQGKILNRKG------------CCPICTEKPGVCT 365
+C C++G+ N+ CPQG R G CCP+ E C+
Sbjct: 1986 DCVRHICLEGQLIRVNQS----QHCPQGAAPPRCGILGLAVRVGGDRCCPLW-ECACRCS 2040
Query: 366 VFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTRSFSWTKSVELV 424
+F D + TFDG Y+L++ SP V V + + +W ++
Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQ---SPDEMLTVHVLDCKSANLGHLNWPPFCLVM 2097
Query: 425 LGESRVSLQQHLTVRWNGSRIAL-------PCRAPHFHIDLDGYLLKVTTKAGLEISW-D 476
L + ++ Q +T+ ++ + P F I+ G++ + T + ++I W
Sbjct: 2098 LNMTHLAHQ--VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLH 2155
Query: 477 GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD---FAESWRVESNEF 533
+ V A+ K + GLCG +G +DL DG+ +D F +SW+V S+
Sbjct: 2156 SSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSS-L 2214
Query: 534 CNRPQRKPVPELCQGTVKVKLRAHREC----QKLKSWEFQTCHSTVDYATFYRSCVTDMC 589
+ Q + P+ C T +C + + + F CH V +F C
Sbjct: 2215 TSVGQTRFRPDSCATT---------DCSPCLRMVSNRTFSACHRFVPPESF--------C 2257
Query: 590 ECPVHKNCY----CESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGC--I 643
E + Y C + Y C + + + W C C + Y C C
Sbjct: 2258 ELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL-CSSDSTYQACVTACEPP 2316
Query: 644 KTCDNWNEIGPCN-KPCVA---GCHCPANLVLHK---GRCIKPVLC 682
KTC + +GP + + C GC C +LH+ CI C
Sbjct: 2317 KTCQD-GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 12/154 (7%)
Query: 56 VLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTY 115
V +PF +C + T R +R CA A + Q + CT +
Sbjct: 292 VSPLPFTASCTSDLCQSMGDVATWCRALAEY-ARACAQAGRPLQGWRTQLRQCTV--HCK 348
Query: 116 NSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNP----LEHLGMCCPT-CPGCVFEG 170
+F + C +S + CV C P E G P CP C F G
Sbjct: 349 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP-CEFHG 407
Query: 171 VQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCP 204
Y G + + C C+CT G+ +C VCP
Sbjct: 408 TLYPPGSVVKED---CNTCTCTSGKWECSTAVCP 438
Score = 34.7 bits (78), Expect = 0.30
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 658 PCVAGCHCPANLVLHKGRCIKPVLCP 683
PC++GC CP L+ H C P CP
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECP 874
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 145 bits (367), Expect = 9e-35
Identities = 95/332 (28%), Positives = 142/332 (42%), Gaps = 10/332 (3%)
Query: 359 EKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSW 417
E+ +C +G H TFDG + G Y L F + V ND + S ++
Sbjct: 146 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 205
Query: 418 TKSVELV-LGESRVSLQQHLTVRWNGSRIALPCRAPHFHID-LDGYLLKVTTKAGLEISW 475
+++V L +GE + L + +T G R+ LP + L GY++ V ++ ++W
Sbjct: 206 SRAVSLFFVGEQEIHLAKEVT--HGGMRVQLPHVMGSARLQQLAGYVI-VRHQSAFTLAW 262
Query: 476 DGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535
DG S V + +P L G GLCGN N +DDL+ G DV +F SW+ ++
Sbjct: 263 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPP 322
Query: 536 RPQRK--PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPV 593
P P P Q + +C+ L F CH+ V F SC +D+C+
Sbjct: 323 GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMG 382
Query: 594 HKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA-VYDTCGPGCIKTCDNWNE 651
+C + Y RAC + G + W Q CK A Y+ C C +C
Sbjct: 383 DVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRAS 442
Query: 652 IGPCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
CV GC+CP L+ G C+ P CP
Sbjct: 443 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 474
Score = 134 bits (338), Expect = 2e-31
Identities = 112/453 (24%), Positives = 174/453 (38%), Gaps = 64/453 (14%)
Query: 244 VYDNGSSFLYDNCTAC---------TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294
V+ +F Y+ C AC +C DS + C C P G GC V
Sbjct: 417 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC-------VA 469
Query: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354
P + C+F ++ G + +C C C G+ EC C
Sbjct: 470 PAECP-CEFHGTLYPPGSVVKE-DCNTCTCTSGKWECSTAVC------------------ 509
Query: 355 PICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTR 413
P C+V GD H+ TFDGR + F TCQY+L K SS F V ++N +
Sbjct: 510 ------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 561
Query: 414 SFSWTKSVELVLGES---RVSLQQHLTV-RWNGSRIALPCRAPHFHI-DLDGYLLKVTTK 468
+ +SV ++L + +V+L Q V ++ +I P F I L L+V T
Sbjct: 562 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 621
Query: 469 AGLEISWDGDSF-VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527
G+ + +D + + + GLCG +NG+ +DD + G + F SW+
Sbjct: 622 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 681
Query: 528 VESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTD 587
S C+ + C ++ + + C L F C + + ++ C D
Sbjct: 682 TLS--ACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 739
Query: 588 MCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCD 647
C C + C C + Y C+R G+ V + + A C+ Y C C +TC
Sbjct: 740 ACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQ 797
Query: 648 NWNEIGPC---------NKPCVAGCHCPANLVL 671
+ C CV GC CP + L
Sbjct: 798 DLASPEACGVDGGDDLSRDECVEGCACPPDTYL 830
Score = 122 bits (305), Expect = 1e-27
Identities = 138/578 (23%), Positives = 205/578 (35%), Gaps = 104/578 (17%)
Query: 66 PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125
PC+ + C+R PV R + AC C+ +S ++
Sbjct: 746 PCLCATLAHYAHLCRRHGLPVDFR------ARLPACALSCE----------ASKEYSPCV 789
Query: 126 EPCVLRQCQEGVVTES-GV---------RCVVHCKNPLE-----HLGMCCPTCP-GCVFE 169
PC R CQ+ E+ GV CV C P + +C P C F+
Sbjct: 790 APCG-RTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 170 GVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRK 229
GV Y G+ P C C G C P +CP GQ C
Sbjct: 849 GVDYPPGDSDIPS---LGHCHCKDGVMSCDSRA-PAAACPA-------GQVFVNC----- 892
Query: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEEC 289
SD++ + C + +V + C C QG + C
Sbjct: 893 ------------SDLHTDLELSRERTCEQ-QLLNLSVSARGPCLSGCACPQGLLRHGDAC 939
Query: 290 LLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILN 349
L PE+ G + F ++ S C C C +G +C C
Sbjct: 940 FL---PEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPCA------------ 982
Query: 350 RKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDA 409
CT +GD HY TFDG F+F G C+ L K S + F V+V+N
Sbjct: 983 ------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS--FSVIVENVN 1028
Query: 410 RRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVT-TK 468
+ K + + +G S + N S + H G+ V +
Sbjct: 1029 CYSSGMICRKFISINVGNSLIVFDDD---SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085
Query: 469 AGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV 528
+ + WD + V V A P +G+L GLCGN++ +++ + + +F SW
Sbjct: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145
Query: 529 ESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDM 588
C P ++C + A +EC L S F+ CH VD FY +C+TD
Sbjct: 1146 VE---C--PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200
Query: 589 CECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC 624
C C + C+C S AY C + G+ V W + C
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 1238
Score = 66.6 bits (161), Expect = 7e-11
Identities = 92/406 (22%), Positives = 154/406 (37%), Gaps = 71/406 (17%)
Query: 318 NCTICACVKGRTECRNKQCIPISSCPQGKILNRKG------------CCPICTEKPGVCT 365
+C C++G+ N+ CPQG R G CCP+ E C+
Sbjct: 2058 DCVRHICLEGQLIRVNQS----QHCPQGAAPPRCGILGLAVRVGGDRCCPLW-ECACRCS 2112
Query: 366 VFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTRSFSWTKSVELV 424
+F D + TFDG Y+L++ SP V V + + +W ++
Sbjct: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQ---SPDEMLTVHVLDCKSANLGHLNWPPFCLVM 2169
Query: 425 LGESRVSLQQHLTVRWNGSRIAL-------PCRAPHFHIDLDGYLLKVTTKAGLEISW-D 476
L + ++ Q +T+ ++ + P F I+ G++ + T + ++I W
Sbjct: 2170 LNMTHLAHQ--VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLH 2227
Query: 477 GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD---FAESWRVESNEF 533
+ V A+ K + GLCG +G +DL DG+ +D F +SW+V S+
Sbjct: 2228 SSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSS-L 2286
Query: 534 CNRPQRKPVPELCQGTVKVKLRAHREC----QKLKSWEFQTCHSTVDYATFYRSCVTDMC 589
+ Q + P+ C T +C + + + F CH V +F C
Sbjct: 2287 TSVGQTRFRPDSCATT---------DCSPCLRMVSNRTFSACHRFVPPESF--------C 2329
Query: 590 ECPVHKNCY----CESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGC--I 643
E + Y C + Y C + + + W C C + Y C C
Sbjct: 2330 ELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL-CSSDSTYQACVTACEPP 2388
Query: 644 KTCDNWNEIGPCN-KPCVA---GCHCPANLVLHK---GRCIKPVLC 682
KTC + +GP + + C GC C +LH+ CI C
Sbjct: 2389 KTCQD-GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 12/154 (7%)
Query: 56 VLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTY 115
V +PF +C + T R +R CA A + Q + CT +
Sbjct: 364 VSPLPFTASCTSDLCQSMGDVATWCRALAEY-ARACAQAGRPLQGWRTQLRQCTV--HCK 420
Query: 116 NSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNP----LEHLGMCCPT-CPGCVFEG 170
+F + C +S + CV C P E G P CP C F G
Sbjct: 421 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP-CEFHG 479
Query: 171 VQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCP 204
Y G + + C C+CT G+ +C VCP
Sbjct: 480 TLYPPGSVVKED---CNTCTCTSGKWECSTAVCP 510
Score = 34.7 bits (78), Expect = 0.30
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 658 PCVAGCHCPANLVLHKGRCIKPVLCP 683
PC++GC CP L+ H C P CP
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECP 946
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 145 bits (367), Expect = 9e-35
Identities = 95/332 (28%), Positives = 142/332 (42%), Gaps = 10/332 (3%)
Query: 359 EKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSW 417
E+ +C +G H TFDG + G Y L F + V ND + S ++
Sbjct: 74 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133
Query: 418 TKSVELV-LGESRVSLQQHLTVRWNGSRIALPCRAPHFHID-LDGYLLKVTTKAGLEISW 475
+++V L +GE + L + +T G R+ LP + L GY++ V ++ ++W
Sbjct: 134 SRAVSLFFVGEQEIHLAKEVT--HGGMRVQLPHVMGSARLQQLAGYVI-VRHQSAFTLAW 190
Query: 476 DGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535
DG S V + +P L G GLCGN N +DDL+ G DV +F SW+ ++
Sbjct: 191 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPP 250
Query: 536 RPQRK--PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPV 593
P P P Q + +C+ L F CH+ V F SC +D+C+
Sbjct: 251 GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMG 310
Query: 594 HKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA-VYDTCGPGCIKTCDNWNE 651
+C + Y RAC + G + W Q CK A Y+ C C +C
Sbjct: 311 DVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRAS 370
Query: 652 IGPCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
CV GC+CP L+ G C+ P CP
Sbjct: 371 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 402
Score = 134 bits (338), Expect = 2e-31
Identities = 112/453 (24%), Positives = 174/453 (38%), Gaps = 64/453 (14%)
Query: 244 VYDNGSSFLYDNCTAC---------TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294
V+ +F Y+ C AC +C DS + C C P G GC V
Sbjct: 345 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC-------VA 397
Query: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354
P + C+F ++ G + +C C C G+ EC C
Sbjct: 398 PAECP-CEFHGTLYPPGSVVKE-DCNTCTCTSGKWECSTAVC------------------ 437
Query: 355 PICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTR 413
P C+V GD H+ TFDGR + F TCQY+L K SS F V ++N +
Sbjct: 438 ------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 489
Query: 414 SFSWTKSVELVLGES---RVSLQQHLTV-RWNGSRIALPCRAPHFHI-DLDGYLLKVTTK 468
+ +SV ++L + +V+L Q V ++ +I P F I L L+V T
Sbjct: 490 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549
Query: 469 AGLEISWDGDSF-VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527
G+ + +D + + + GLCG +NG+ +DD + G + F SW+
Sbjct: 550 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 609
Query: 528 VESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTD 587
S C+ + C ++ + + C L F C + + ++ C D
Sbjct: 610 TLS--ACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 667
Query: 588 MCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCD 647
C C + C C + Y C+R G+ V + + A C+ Y C C +TC
Sbjct: 668 ACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQ 725
Query: 648 NWNEIGPC---------NKPCVAGCHCPANLVL 671
+ C CV GC CP + L
Sbjct: 726 DLASPEACGVDGGDDLSRDECVEGCACPPDTYL 758
Score = 122 bits (305), Expect = 1e-27
Identities = 138/578 (23%), Positives = 205/578 (35%), Gaps = 104/578 (17%)
Query: 66 PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125
PC+ + C+R PV R + AC C+ +S ++
Sbjct: 674 PCLCATLAHYAHLCRRHGLPVDFR------ARLPACALSCE----------ASKEYSPCV 717
Query: 126 EPCVLRQCQEGVVTES-GV---------RCVVHCKNPLE-----HLGMCCPTCP-GCVFE 169
PC R CQ+ E+ GV CV C P + +C P C F+
Sbjct: 718 APCG-RTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 170 GVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRK 229
GV Y G+ P C C G C P +CP GQ C
Sbjct: 777 GVDYPPGDSDIPS---LGHCHCKDGVMSCDSRA-PAAACPA-------GQVFVNC----- 820
Query: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEEC 289
SD++ + C + +V + C C QG + C
Sbjct: 821 ------------SDLHTDLELSRERTCEQ-QLLNLSVSARGPCLSGCACPQGLLRHGDAC 867
Query: 290 LLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILN 349
L PE+ G + F ++ S C C C +G +C C
Sbjct: 868 FL---PEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPCA------------ 910
Query: 350 RKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDA 409
CT +GD HY TFDG F+F G C+ L K S + F V+V+N
Sbjct: 911 ------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS--FSVIVENVN 956
Query: 410 RRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVT-TK 468
+ K + + +G S + N S + H G+ V +
Sbjct: 957 CYSSGMICRKFISINVGNSLIVFDDD---SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
Query: 469 AGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV 528
+ + WD + V V A P +G+L GLCGN++ +++ + + +F SW
Sbjct: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
Query: 529 ESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDM 588
C P ++C + A +EC L S F+ CH VD FY +C+TD
Sbjct: 1074 VE---C--PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1128
Query: 589 CECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC 624
C C + C+C S AY C + G+ V W + C
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 1166
Score = 66.6 bits (161), Expect = 7e-11
Identities = 92/406 (22%), Positives = 154/406 (37%), Gaps = 71/406 (17%)
Query: 318 NCTICACVKGRTECRNKQCIPISSCPQGKILNRKG------------CCPICTEKPGVCT 365
+C C++G+ N+ CPQG R G CCP+ E C+
Sbjct: 1986 DCVRHICLEGQLIRVNQS----QHCPQGAAPPRCGILGLAVRVGGDRCCPLW-ECACRCS 2040
Query: 366 VFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTRSFSWTKSVELV 424
+F D + TFDG Y+L++ SP V V + + +W ++
Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQ---SPDEMLTVHVLDCKSANLGHLNWPPFCLVM 2097
Query: 425 LGESRVSLQQHLTVRWNGSRIAL-------PCRAPHFHIDLDGYLLKVTTKAGLEISW-D 476
L + ++ Q +T+ ++ + P F I+ G++ + T + ++I W
Sbjct: 2098 LNMTHLAHQ--VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLH 2155
Query: 477 GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD---FAESWRVESNEF 533
+ V A+ K + GLCG +G +DL DG+ +D F +SW+V S+
Sbjct: 2156 SSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSS-L 2214
Query: 534 CNRPQRKPVPELCQGTVKVKLRAHREC----QKLKSWEFQTCHSTVDYATFYRSCVTDMC 589
+ Q + P+ C T +C + + + F CH V +F C
Sbjct: 2215 TSVGQTRFRPDSCATT---------DCSPCLRMVSNRTFSACHRFVPPESF--------C 2257
Query: 590 ECPVHKNCY----CESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGC--I 643
E + Y C + Y C + + + W C C + Y C C
Sbjct: 2258 ELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL-CSSDSTYQACVTACEPP 2316
Query: 644 KTCDNWNEIGPCN-KPCVA---GCHCPANLVLHK---GRCIKPVLC 682
KTC + +GP + + C GC C +LH+ CI C
Sbjct: 2317 KTCQD-GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 12/154 (7%)
Query: 56 VLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTY 115
V +PF +C + T R +R CA A + Q + CT +
Sbjct: 292 VSPLPFTASCTSDLCQSMGDVATWCRALAEY-ARACAQAGRPLQGWRTQLRQCTV--HCK 348
Query: 116 NSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNP----LEHLGMCCPT-CPGCVFEG 170
+F + C +S + CV C P E G P CP C F G
Sbjct: 349 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP-CEFHG 407
Query: 171 VQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCP 204
Y G + + C C+CT G+ +C VCP
Sbjct: 408 TLYPPGSVVKED---CNTCTCTSGKWECSTAVCP 438
Score = 34.7 bits (78), Expect = 0.30
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 658 PCVAGCHCPANLVLHKGRCIKPVLCP 683
PC++GC CP L+ H C P CP
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECP 874
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 145 bits (367), Expect = 9e-35
Identities = 95/332 (28%), Positives = 142/332 (42%), Gaps = 10/332 (3%)
Query: 359 EKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSW 417
E+ +C +G H TFDG + G Y L F + V ND + S ++
Sbjct: 146 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 205
Query: 418 TKSVELV-LGESRVSLQQHLTVRWNGSRIALPCRAPHFHID-LDGYLLKVTTKAGLEISW 475
+++V L +GE + L + +T G R+ LP + L GY++ V ++ ++W
Sbjct: 206 SRAVSLFFVGEQEIHLAKEVT--HGGMRVQLPHVMGSARLQQLAGYVI-VRHQSAFTLAW 262
Query: 476 DGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535
DG S V + +P L G GLCGN N +DDL+ G DV +F SW+ ++
Sbjct: 263 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPP 322
Query: 536 RPQRK--PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPV 593
P P P Q + +C+ L F CH+ V F SC +D+C+
Sbjct: 323 GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMG 382
Query: 594 HKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA-VYDTCGPGCIKTCDNWNE 651
+C + Y RAC + G + W Q CK A Y+ C C +C
Sbjct: 383 DVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRAS 442
Query: 652 IGPCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
CV GC+CP L+ G C+ P CP
Sbjct: 443 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 474
Score = 134 bits (338), Expect = 2e-31
Identities = 112/453 (24%), Positives = 174/453 (38%), Gaps = 64/453 (14%)
Query: 244 VYDNGSSFLYDNCTAC---------TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294
V+ +F Y+ C AC +C DS + C C P G GC V
Sbjct: 417 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC-------VA 469
Query: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354
P + C+F ++ G + +C C C G+ EC C
Sbjct: 470 PAECP-CEFHGTLYPPGSVVKE-DCNTCTCTSGKWECSTAVC------------------ 509
Query: 355 PICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTR 413
P C+V GD H+ TFDGR + F TCQY+L K SS F V ++N +
Sbjct: 510 ------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 561
Query: 414 SFSWTKSVELVLGES---RVSLQQHLTV-RWNGSRIALPCRAPHFHI-DLDGYLLKVTTK 468
+ +SV ++L + +V+L Q V ++ +I P F I L L+V T
Sbjct: 562 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 621
Query: 469 AGLEISWDGDSF-VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527
G+ + +D + + + GLCG +NG+ +DD + G + F SW+
Sbjct: 622 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 681
Query: 528 VESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTD 587
S C+ + C ++ + + C L F C + + ++ C D
Sbjct: 682 TLS--ACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 739
Query: 588 MCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCD 647
C C + C C + Y C+R G+ V + + A C+ Y C C +TC
Sbjct: 740 ACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQ 797
Query: 648 NWNEIGPC---------NKPCVAGCHCPANLVL 671
+ C CV GC CP + L
Sbjct: 798 DLASPEACGVDGGDDLSRDECVEGCACPPDTYL 830
Score = 122 bits (305), Expect = 1e-27
Identities = 138/578 (23%), Positives = 205/578 (35%), Gaps = 104/578 (17%)
Query: 66 PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125
PC+ + C+R PV R + AC C+ +S ++
Sbjct: 746 PCLCATLAHYAHLCRRHGLPVDFR------ARLPACALSCE----------ASKEYSPCV 789
Query: 126 EPCVLRQCQEGVVTES-GV---------RCVVHCKNPLE-----HLGMCCPTCP-GCVFE 169
PC R CQ+ E+ GV CV C P + +C P C F+
Sbjct: 790 APCG-RTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 170 GVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRK 229
GV Y G+ P C C G C P +CP GQ C
Sbjct: 849 GVDYPPGDSDIPS---LGHCHCKDGVMSCDSRA-PAAACPA-------GQVFVNC----- 892
Query: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEEC 289
SD++ + C + +V + C C QG + C
Sbjct: 893 ------------SDLHTDLELSRERTCEQ-QLLNLSVSARGPCLSGCACPQGLLRHGDAC 939
Query: 290 LLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILN 349
L PE+ G + F ++ S C C C +G +C C
Sbjct: 940 FL---PEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPCA------------ 982
Query: 350 RKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDA 409
CT +GD HY TFDG F+F G C+ L K S + F V+V+N
Sbjct: 983 ------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS--FSVIVENVN 1028
Query: 410 RRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVT-TK 468
+ K + + +G S + N S + H G+ V +
Sbjct: 1029 CYSSGMICRKFISINVGNSLIVFDDD---SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085
Query: 469 AGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV 528
+ + WD + V V A P +G+L GLCGN++ +++ + + +F SW
Sbjct: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145
Query: 529 ESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDM 588
C P ++C + A +EC L S F+ CH VD FY +C+TD
Sbjct: 1146 VE---C--PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1200
Query: 589 CECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC 624
C C + C+C S AY C + G+ V W + C
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 1238
Score = 66.6 bits (161), Expect = 7e-11
Identities = 92/406 (22%), Positives = 154/406 (37%), Gaps = 71/406 (17%)
Query: 318 NCTICACVKGRTECRNKQCIPISSCPQGKILNRKG------------CCPICTEKPGVCT 365
+C C++G+ N+ CPQG R G CCP+ E C+
Sbjct: 2058 DCVRHICLEGQLIRVNQS----QHCPQGAAPPRCGILGLAVRVGGDRCCPLW-ECACRCS 2112
Query: 366 VFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTRSFSWTKSVELV 424
+F D + TFDG Y+L++ SP V V + + +W ++
Sbjct: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQ---SPDEMLTVHVLDCKSANLGHLNWPPFCLVM 2169
Query: 425 LGESRVSLQQHLTVRWNGSRIAL-------PCRAPHFHIDLDGYLLKVTTKAGLEISW-D 476
L + ++ Q +T+ ++ + P F I+ G++ + T + ++I W
Sbjct: 2170 LNMTHLAHQ--VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLH 2227
Query: 477 GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD---FAESWRVESNEF 533
+ V A+ K + GLCG +G +DL DG+ +D F +SW+V S+
Sbjct: 2228 SSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSS-L 2286
Query: 534 CNRPQRKPVPELCQGTVKVKLRAHREC----QKLKSWEFQTCHSTVDYATFYRSCVTDMC 589
+ Q + P+ C T +C + + + F CH V +F C
Sbjct: 2287 TSVGQTRFRPDSCATT---------DCSPCLRMVSNRTFSACHRFVPPESF--------C 2329
Query: 590 ECPVHKNCY----CESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGC--I 643
E + Y C + Y C + + + W C C + Y C C
Sbjct: 2330 ELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL-CSSDSTYQACVTACEPP 2388
Query: 644 KTCDNWNEIGPCN-KPCVA---GCHCPANLVLHK---GRCIKPVLC 682
KTC + +GP + + C GC C +LH+ CI C
Sbjct: 2389 KTCQD-GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2433
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 12/154 (7%)
Query: 56 VLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTY 115
V +PF +C + T R +R CA A + Q + CT +
Sbjct: 364 VSPLPFTASCTSDLCQSMGDVATWCRALAEY-ARACAQAGRPLQGWRTQLRQCTV--HCK 420
Query: 116 NSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNP----LEHLGMCCPT-CPGCVFEG 170
+F + C +S + CV C P E G P CP C F G
Sbjct: 421 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP-CEFHG 479
Query: 171 VQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCP 204
Y G + + C C+CT G+ +C VCP
Sbjct: 480 TLYPPGSVVKED---CNTCTCTSGKWECSTAVCP 510
Score = 34.7 bits (78), Expect = 0.30
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 658 PCVAGCHCPANLVLHKGRCIKPVLCP 683
PC++GC CP L+ H C P CP
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECP 946
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 138 bits (348), Expect = 1e-32
Identities = 92/324 (28%), Positives = 132/324 (40%), Gaps = 46/324 (14%)
Query: 67 CIMCVCLNKEVTCKREKCPVLSRDCALA---IKQRGA--CCEQCK-----GCTYEGNTYN 116
C C C V CK C + CA + Q A CC +C C +E +
Sbjct: 46 CQSCRCHGDIVICKPAVCR--NPQCAFEKGEVLQIAANQCCPECVLRTPGSCHHEKKIHE 103
Query: 117 SSFKWQSPAEPCVLRQCQEGVVTESGVRCVV----HCKNPLEHLGMCCPTCPG----CVF 168
+W S PC + C G V + C H + G CCP C G C +
Sbjct: 104 HGTEWAS--SPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCSY 161
Query: 169 EGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIP-PGQCCPKCLGQ 227
EG +Q+GE+++ S+C KC C G QC C L C Q + + PG+CCP+C +
Sbjct: 162 EGHVFQDGEDWRL--SRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQCSAR 219
Query: 228 RKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEG--- 284
SC VY++G + + CT C C V C ++ P C +GQ
Sbjct: 220 ---------SCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSRARR 270
Query: 285 ---CCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISS 341
CCEEC+ C + + EMW C C C G+ C+ +C +
Sbjct: 271 HGQCCEECV-----SPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVEC 325
Query: 342 CPQGKILNRKG-CCPICTEKPGVC 364
++++ G CCP C + G C
Sbjct: 326 ARDEELIHLDGKCCPECISRNGYC 349
Score = 125 bits (314), Expect = 1e-28
Identities = 96/323 (29%), Positives = 129/323 (39%), Gaps = 45/323 (13%)
Query: 65 NPCIMCVCLNKEVTCKREKCPVLSRDCA---LAIKQRGACCEQCKG----CTYEGNTYNS 117
+PC +C C + EV C + CP LS C LA G+CC C G C+YEG+ +
Sbjct: 111 SPCSVCSCNHGEVRCTPQPCPPLS--CGHQELAFIPEGSCCPVCVGLGKPCSYEGHVFQD 168
Query: 118 SFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHL----GMCCPTCP--GCVFEGV 171
W+ C C+ GV +C N E + G CCP C C G
Sbjct: 169 GEDWR--LSRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQCSARSCSAAGQ 226
Query: 172 QYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHI-PPGQCCPKCLGQRKV 230
Y+ GE++ + CT C C G +C ++ C L C + S GQCC +C+
Sbjct: 227 VYEHGEQWSE--NACTTCICDRGEVRCHKQACLPLRCGKGQSRARRHGQCCEECVS---- 280
Query: 231 FDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQE------G 284
P GSC + V + C C C V C+ C + +E
Sbjct: 281 ---PAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECARDEELIHLDGK 337
Query: 285 CCEECLLR---VPPEDIKVCKFGN----KIFQDGEMWSSINCTICACVKGRTECRNKQCI 337
CC EC+ R E+ N K +GE W C +C C + C C
Sbjct: 338 CCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYEPSCP 397
Query: 338 PISSCPQGKI-LNRKG-CCPICT 358
P CP G + L KG CCP CT
Sbjct: 398 P---CPVGTLALEVKGQCCPDCT 417
Score = 125 bits (313), Expect = 2e-28
Identities = 71/228 (31%), Positives = 99/228 (43%), Gaps = 31/228 (13%)
Query: 159 CCPTC----PG-CVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCP-QHL 212
CCP C PG C E ++ G E+ S C+ CSC G +C + CP LSC Q L
Sbjct: 83 CCPECVLRTPGSCHHEKKIHEHGTEWA--SSPCSVCSCNHGEVRCTPQPCPPLSCGHQEL 140
Query: 213 SHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKC 272
+ IP G CCP C+G K C + V+ +G + C C CR+ C
Sbjct: 141 AFIPEGSCCPVCVGLGK-------PCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQ 193
Query: 273 SHPGGCDQGQE------GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVK 326
P C+Q + CC +C R C ++++ GE WS CT C C +
Sbjct: 194 CQPLFCNQDETVVRVPGKCCPQCSARS-------CSAAGQVYEHGEQWSENACTTCICDR 246
Query: 327 GRTECRNKQCIPISSCPQGKILNRK--GCCPICTEKPGVCTVFGDPHY 372
G C + C+P+ C +G+ R+ CC C G C+ G Y
Sbjct: 247 GEVRCHKQACLPL-RCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRY 293
Score = 89.0 bits (219), Expect = 1e-17
Identities = 102/379 (26%), Positives = 139/379 (36%), Gaps = 79/379 (20%)
Query: 63 TDNPCIMCVCLNKEVTCKREKC-PVLSRDCALAIKQRGACCEQC----KGCTYEGNTYNS 117
++N C C+C EV C ++ C P+ ++ G CCE+C C+Y+G
Sbjct: 235 SENACTTCICDRGEVRCHKQACLPLRCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQ 294
Query: 118 SFKWQSPAEPCVLRQCQEGVVT-ESGVRCVVHCKNPLE--HL-GMCCPTCPG----CVFE 169
W+ A C C G VT ++G V C E HL G CCP C CV
Sbjct: 295 DEMWKGSA--CEFCMCDHGQVTCQTGECAKVECARDEELIHLDGKCCPECISRNGYCV-- 350
Query: 170 GVQYQEGEEFQ----------PEGSK-----CTKCSCTGGRTQCVREVCPILSCP-QHLS 213
Y+E EF PEG K C C C G + C CP CP L+
Sbjct: 351 ---YEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYEPSCP--PCPVGTLA 405
Query: 214 HIPPGQCCPKCLGQRKVFD-LPFGSCLFRSDVYDNGSSFLYDNCTACTC-------RDST 265
GQCCP C D L D+ + + L + +C
Sbjct: 406 LEVKGQCCPDCTSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSLC 465
Query: 266 VVCKRKCSHPGGCDQGQE-GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI--- 321
+ C+ +CS C G E C+ LL + + C G+ +QD +C +
Sbjct: 466 LACQPQCS---TCTSGLECSSCQPPLLMRHGQCVPTC--GDGFYQDRH-----SCAVCHE 515
Query: 322 -CACVKGRTECRNKQCIPI-------------SSCPQGKILNRKGCCPICTEKPGVCTVF 367
CA G TE K C+ SSC +G NR+G C C + C
Sbjct: 516 SCAGCWGPTE---KHCLACRDPLHVLRDGGCESSCGKG-FYNRQGTCSACDQSCDSCGP- 570
Query: 368 GDPHYNTFDGRTFNFQGTC 386
P T +T G C
Sbjct: 571 SSPRCLTCTEKTVLHDGKC 589
Score = 76.3 bits (186), Expect = 9e-14
Identities = 41/142 (28%), Positives = 67/142 (47%), Gaps = 13/142 (9%)
Query: 236 GSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCK-RKCSHPG-GCDQGQ------EGCCE 287
G+C+++ + + + + D+C +C C V+CK C +P ++G+ CC
Sbjct: 26 GACVYQDSLLADATIWKPDSCQSCRCHGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCP 85
Query: 288 ECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKI 347
EC+LR P C KI + G W+S C++C+C G C + C P+S Q
Sbjct: 86 ECVLRTPGS----CHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELA 141
Query: 348 LNRKG-CCPICTEKPGVCTVFG 368
+G CCP+C C+ G
Sbjct: 142 FIPEGSCCPVCVGLGKPCSYEG 163
Score = 53.9 bits (128), Expect = 5e-07
Identities = 81/343 (23%), Positives = 110/343 (32%), Gaps = 81/343 (23%)
Query: 52 NEGEVLQIPF---ITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGC 108
N EV +IP D PC +C C +VTC CP LA++ +G CC C
Sbjct: 361 NASEVKRIPEGEKWEDGPCKVCECRGAQVTCYEPSCPPCPVG-TLALEVKGQCCPDCTSV 419
Query: 109 TYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVF 168
+ S QSP + C L CQ+ CV C G C C
Sbjct: 420 HCHPDCLTCS---QSP-DHCDL--CQDPTKLLQNGWCVHSCGLGFYQAGSLCLAC----- 468
Query: 169 EGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQR 228
QP+ S +CT G C P + H GQC P C
Sbjct: 469 -----------QPQCS-----TCTSGLE------CSSCQPPLLMRH---GQCVPTC---- 499
Query: 229 KVFDLPFGSCLFRSDVYDNGSSFLYDNCTAC---------TCRDSTVV-----CKRKCSH 274
G ++ + + +++C C CRD V C+ C
Sbjct: 500 -------GDGFYQD---RHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGK 549
Query: 275 PGGCDQGQEGCCEECLLRVPPEDIKVCKFGNK-IFQDGEMWSSINCTICACVKGRTECRN 333
QG C++ P + K + DG+ S A GR + +
Sbjct: 550 GFYNRQGTCSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCH 609
Query: 334 KQCIPIS--------SCPQGKILNRKGCCPICTE----KPGVC 364
C S +C K L + C P C E GVC
Sbjct: 610 NSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSDHGVC 652
Score = 41.2 bits (95), Expect = 0.003
Identities = 81/352 (23%), Positives = 118/352 (33%), Gaps = 71/352 (20%)
Query: 45 GSVAKCENEGEVLQIPFITDNPCIMC---VCL---NKEVTCKREK----------CPVLS 88
GS +C P +D CI C + L N +C+ E+ C L
Sbjct: 756 GSCTECHPTCRQCHGPLESD--CISCYPHISLTNGNCRTSCREEQFLNLVGYCADCHHLC 813
Query: 89 RDCALAIKQRGACCEQCKGCTYE--GNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCV 146
+ CA + G+ C +C+ Y G+ AE ++C T G R
Sbjct: 814 QHCAADLHNTGSICLRCQNAHYLLLGDHCVPDCPSGYYAERGACKKCHSSCRTCQG-RGP 872
Query: 147 VHCKN-----PLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQC--- 198
C + L H G C TC F G + QP + C C T C
Sbjct: 873 FSCSSCDTNLVLSHTGTCSTTC----FPGHYLDDNHVCQPCNTHCGSCDSQASCTSCRDP 928
Query: 199 ----VREVCPILSC-PQHLSHIPPGQC------CPKCLGQRKVFDLPFGSCLFRSDVYDN 247
+ C SC PQ+ C C C G K CL D Y
Sbjct: 929 NKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSACSGPLKT------DCLQCMDGYVL 982
Query: 248 GSSFLYDNCTACTCRDSTVVCK-----RKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCK 302
+ C + +DS +CK +C P C + C+ L + + ++ C
Sbjct: 983 QDGACVEQCLSSFYQDSG-LCKCDSYCLQCQGPHECTR-----CKGPFLLLEAQCVQEC- 1035
Query: 303 FGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354
G F D + CT AC +G +C ++ + C G L + G C
Sbjct: 1036 -GKGYFAD---HAKHKCT--ACPQGCLQCSHRDRCHL--CDHGFFL-KSGLC 1078
Score = 35.0 bits (79), Expect = 0.23
Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 12/80 (15%)
Query: 293 VPPEDIKVCKFGNKIFQDGEMWSSINCTICAC-----VKGRTECRNKQCIPISSCPQGKI 347
+P C + + + D +W +C C C + CRN QC + +G++
Sbjct: 20 LPHHSEGACVYQDSLLADATIWKPDSCQSCRCHGDIVICKPAVCRNPQC----AFEKGEV 75
Query: 348 LN--RKGCCPICT-EKPGVC 364
L CCP C PG C
Sbjct: 76 LQIAANQCCPECVLRTPGSC 95
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 135 bits (340), Expect = 1e-31
Identities = 110/383 (28%), Positives = 157/383 (40%), Gaps = 73/383 (19%)
Query: 29 LNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNKEVT--CKREKCPV 86
LNC P + + +C + + P I D C + + NK C+ +KCP
Sbjct: 514 LNC---PFGFLTDAQNCEICECRPRPKKCR-PIICDKYCPLGLLKNKHGCDICRCKKCPE 569
Query: 87 LS--RDCALAIKQRGACCEQCKG----------------CTYEGNTYNSSFKWQSPAEPC 128
LS + C L +Q C CK T +G+ + + W C
Sbjct: 570 LSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESWHDGCREC 629
Query: 129 VLRQCQEGVVTESGVRCVVH-CKNPLEHLGMCCPTC--------PGCVFEGVQYQEGEEF 179
C G + + C V C NP H G CCP+C P + + G E+
Sbjct: 630 Y---CLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEY 686
Query: 180 QPEGS-----KCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLP 234
EG CT+C+C GR C EVCP L C Q+ S CCP+C Q P
Sbjct: 687 FVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLC-QNPSRTQDS-CCPQCTDQ------P 738
Query: 235 FGSCLFRS------------DVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQ-- 280
F L R+ D++ S+ D CT+C C DS + C + C++
Sbjct: 739 FRPSLSRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFSESCPSVSCERPV 798
Query: 281 ---GQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCI 337
GQ CC C+ P+ + VC F K + D E W +CT C C++G+T C C
Sbjct: 799 LRKGQ--CCPYCIEDTIPKKV-VCHFSGKAYADEERWDLDSCTHCYCLQGQTLCSTVSCP 855
Query: 338 PISSCPQGKILNRKG-CCPICTE 359
P+ P + +N +G CCP+C E
Sbjct: 856 PL---PCVEPINVEGSCCPMCPE 875
Score = 85.5 bits (210), Expect = 1e-16
Identities = 60/224 (26%), Positives = 94/224 (41%), Gaps = 28/224 (12%)
Query: 157 GMCCP-------TCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCP 209
G CC T P CVF V+Y +G+ F+ + C C C GG C C ++C
Sbjct: 320 GKCCDVFECVNDTKPACVFNNVEYYDGDMFRMD--NCRFCRCQGGVAICFTAQCGEINCE 377
Query: 210 QHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDS----- 264
++ ++P G+CCP C F+ P G C + +G + D+CT C C +
Sbjct: 378 RY--YVPEGECCPVCEDPVYPFNNPAG-CYANGLILAHGDRWREDDCTFCQCVNGERHCV 434
Query: 265 TVVCKRKCSH----PGGCDQGQEGCCEECLLRVPPE---DIKVCKFGNKIFQDGEMWSSI 317
VC + C++ PG C C E ++ V P ++ C K +G
Sbjct: 435 ATVCGQTCTNPVKVPGEC---CPVCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHN 491
Query: 318 NCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKP 361
C C C+ C ++ +CP G + + + C IC +P
Sbjct: 492 GCRTCQCINTEELCSERKQGCTLNCPFGFLTDAQN-CEICECRP 534
Score = 79.3 bits (194), Expect = 1e-14
Identities = 81/343 (23%), Positives = 112/343 (32%), Gaps = 67/343 (19%)
Query: 64 DNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCK----------------G 107
++ C C C+N E C C + C +K G CC C+
Sbjct: 418 EDDCTFCQCVNGERHCVATVC---GQTCTNPVKVPGECCPVCEEPTIITVDPPACGELSN 474
Query: 108 CTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCV 167
CT G + FK R CQ C+ + E C CP
Sbjct: 475 CTLTGKDCINGFKRDHNG----CRTCQ----------CINTEELCSERKQGCTLNCPFGF 520
Query: 168 FEGVQYQEGEEFQPEGSKCTKCSCTG-----------GRTQCVREVCPILSC----PQHL 212
Q E E +P KC C G C + CP LSC P
Sbjct: 521 LTDAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPELSCSKICPLGF 580
Query: 213 SHIPPGQCCPKCLGQRKVFDLPF--GSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCK- 269
G KC P G+CL + +D C C C + +C
Sbjct: 581 QQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESWHDGCRECYCLNGREMCAL 640
Query: 270 ---------RKCSHPGGCDQGQEGCCEECLLRVPPEDI-KVCKF-GNKIFQDGEMWSSIN 318
HPG C C ++ +++ P +C G + F +GE W+ +
Sbjct: 641 ITCPVPACGNPTIHPGQCCPS---CADDFVVQKPELSTPSICHAPGGEYFVEGETWNIDS 697
Query: 319 CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKP 361
CT C C GR C + C P+ Q + CCP CT++P
Sbjct: 698 CTQCTCHSGRVLCETEVCPPLLC--QNPSRTQDSCCPQCTDQP 738
Score = 78.6 bits (192), Expect = 2e-14
Identities = 66/231 (28%), Positives = 93/231 (40%), Gaps = 34/231 (14%)
Query: 187 TKCSCTGGRTQCVREVCPILSCPQHLSHIP--PGQCCP--KCLGQRKVFDLPFGSCLFRS 242
T+C C G C VC + S P+ +S PG+CC +C+ K +C+F +
Sbjct: 289 TRCECLSGL--CGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNDTKP------ACVFNN 340
Query: 243 DVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQ--EG-CCEECLLRVPPEDIK 299
Y +G F DNC C C+ +C C++ EG CC C V P +
Sbjct: 341 VEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCERYYVPEGECCPVCEDPVYPFNNP 400
Query: 300 V-CKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICT 358
C I G+ W +CT C CV G C C + P + CCP+C
Sbjct: 401 AGCYANGLILAHGDRWREDDCTFCQCVNGERHCVATVCGQTCTNP---VKVPGECCPVC- 456
Query: 359 EKPGV-------------CTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSS 396
E+P + CT+ G N F R N TCQ + T++ S
Sbjct: 457 EEPTIITVDPPACGELSNCTLTGKDCINGFK-RDHNGCRTCQCINTEELCS 506
Score = 52.4 bits (124), Expect = 1e-06
Identities = 57/214 (26%), Positives = 79/214 (36%), Gaps = 47/214 (21%)
Query: 177 EEFQPEGSKCTKCS-CTGGRTQCVREVCPILSCPQHLSHI------PPGQCCP--KC--- 224
E + P G C S C C+R+VC P +L+ + PG+CC +C
Sbjct: 195 EGYAPPGECCPLPSRCVCNPAGCLRKVCQ----PGNLNILVSKASGKPGECCDLYECKPV 250
Query: 225 --LGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNC----TACTCRDSTVVCKRKCSHPGGC 278
+ R V P D Y+ D C T C C +C G
Sbjct: 251 FGVDCRTVECPPVQQTACPPDSYETQVRLTADGCCTLPTRCECLSG--LCGFPVCEVGST 308
Query: 279 DQ------GQEG-CCE--ECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRT 329
+ G G CC+ EC+ P C F N + DG+M+ NC C C G
Sbjct: 309 PRIVSRGDGTPGKCCDVFECVNDTKP----ACVFNNVEYYDGDMFRMDNCRFCRCQGGVA 364
Query: 330 ECRNKQCIPISS----CPQGKILNRKGCCPICTE 359
C QC I+ P+G+ CCP+C +
Sbjct: 365 ICFTAQCGEINCERYYVPEGE------CCPVCED 392
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.486
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,110,132
Number of Sequences: 37866
Number of extensions: 1788953
Number of successful extensions: 6520
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 158
Number of HSP's that attempted gapping in prelim test: 4575
Number of HSP's gapped (non-prelim): 1117
length of query: 685
length of database: 18,247,518
effective HSP length: 109
effective length of query: 576
effective length of database: 14,120,124
effective search space: 8133191424
effective search space used: 8133191424
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.